Rattus norvegicus

0 known processes

Zap70

zeta-chain (TCR) associated protein kinase

(Aliases: Srk,MGC108902)

Zap70 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of metabolic processGO:00098923310.100
response to tumor cellGO:000234740.097
cell activationGO:0001775970.095
Human Rat
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.083
negative regulation of immune response to tumor cellGO:000283820.078
leukocyte cell cell adhesionGO:000715940.074
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.072
positive regulation of nitrogen compound metabolic processGO:00511733340.072
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.070
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.069
natural killer cell mediated immune response to tumor cellGO:000242310.069
regulation of molecular functionGO:00650093980.068
negative regulation of response to tumor cellGO:000283520.063
lymphocyte activationGO:0046649430.062
Human
programmed cell deathGO:00125013920.054
negative regulation of cellular metabolic processGO:00313242810.053
leukocyte activationGO:0045321760.051
Human Rat
response to biotic stimulusGO:00096072260.050
neuron differentiationGO:00301823680.050
immune response to tumor cellGO:000241830.049
positive regulation of cellular biosynthetic processGO:00313282950.049
response to external biotic stimulusGO:00432072210.048
regulation of cell proliferationGO:00421273590.045
regulation of rna metabolic processGO:00512523910.045
positive regulation of nucleobase containing compound metabolic processGO:00459353190.044
rna metabolic processGO:00160704060.043
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.043
negative regulation of natural killer cell mediated immunityGO:000271640.043
positive regulation of transcription dna templatedGO:00458931970.042
response to oxidative stressGO:00069791860.042
cellular response to stressGO:00335542690.042
immune responseGO:00069551040.042
Human Rat
regulation of signal transductionGO:00099663180.041
regulation of immune response to tumor cellGO:000283730.041
intracellular signal transductionGO:00355563140.040
defense responseGO:00069521940.039
response to extracellular stimulusGO:00099913800.039
transcription dna templatedGO:00063513770.038
regulation of catalytic activityGO:00507903040.037
rna biosynthetic processGO:00327743800.035
regulation of nucleic acid templated transcriptionGO:19035063800.035
nucleobase containing small molecule metabolic processGO:00550863160.033
positive regulation of biosynthetic processGO:00098913190.033
metal ion transportGO:00300012890.033
negative regulation of macromolecule metabolic processGO:00106052600.032
response to radiationGO:00093141370.031
positive regulation of macromolecule biosynthetic processGO:00105572470.031
behaviorGO:00076102050.030
negative regulation of nitrogen compound metabolic processGO:00511721610.030
response to other organismGO:00517072200.030
regulation of transcription dna templatedGO:00063553740.030
immune system processGO:00023762040.029
Human Rat
response to growth factorGO:00708481890.029
positive regulation of rna biosynthetic processGO:19026801970.029
positive regulation of molecular functionGO:00440932300.028
response to estrogenGO:00436272320.028
homeostatic processGO:00425923310.028
leukocyte mediated immunityGO:0002443280.028
Rat
ion homeostasisGO:00508012120.028
transcription from rna polymerase ii promoterGO:00063662520.028
regulation of programmed cell deathGO:00430673410.027
regulation of rna biosynthetic processGO:20011413810.027
positive regulation of response to stimulusGO:00485842850.026
Rat
response to reactive oxygen speciesGO:00003021200.026
epithelium developmentGO:0060429960.026
positive regulation of cell proliferationGO:00082842490.026
organic acid metabolic processGO:00060822920.026
negative regulation of biosynthetic processGO:00098901680.026
regulation of cellular protein metabolic processGO:00322682670.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
response to toxic substanceGO:00096361330.025
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.025
negative regulation of macromolecule biosynthetic processGO:00105581480.024
t cell activationGO:0042110290.024
Human
apoptotic processGO:00069153810.024
positive regulation of developmental processGO:00510942830.024
Human Zebrafish
positive regulation of rna metabolic processGO:00512542030.024
regulation of phosphorus metabolic processGO:00511743490.024
single organism biosynthetic processGO:00447113420.023
cation transportGO:00068123820.023
negative regulation of cell deathGO:00605482290.023
negative regulation of innate immune responseGO:004582440.023
response to nutrientGO:00075842480.023
protein phosphorylationGO:00064683450.023
Human Rat
negative regulation of molecular functionGO:00440921330.023
inflammatory responseGO:00069541500.022
regulation of neurogenesisGO:00507672470.022
cation homeostasisGO:00550801950.022
cellular amine metabolic processGO:0044106380.022
reactive oxygen species biosynthetic processGO:190340980.022
protein complex biogenesisGO:00702712630.021
regulation of transcription from rna polymerase ii promoterGO:00063572340.021
single organism reproductive processGO:00447022970.021
positive regulation of phosphorus metabolic processGO:00105622620.021
positive regulation of leukocyte differentiationGO:1902107130.021
Human
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
response to cytokineGO:00340972150.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
regulation of cellular amino acid metabolic processGO:000652120.020
negative regulation of apoptotic processGO:00430661810.020
localization of cellGO:00516742020.020
Zebrafish
lipid biosynthetic processGO:00086101280.020
cellular component assemblyGO:00226073600.020
regulation of response to tumor cellGO:000283430.020
regulation of intracellular signal transductionGO:19025312180.020
response to inorganic substanceGO:00100353770.020
cellular component biogenesisGO:00440853680.020
regulation of necroptotic processGO:006054420.019
ribonucleotide metabolic processGO:00092592310.019
multi multicellular organism processGO:00447061380.019
negative regulation of rna biosynthetic processGO:19026791180.019
regulation of cell killingGO:0031341120.019
response to estradiolGO:00323551640.019
neuron projection developmentGO:00311752730.019
necroptotic processGO:007026620.018
positive regulation of cellular amine metabolic processGO:003324030.018
cell morphogenesis involved in differentiationGO:00009041190.018
positive regulation of gene expressionGO:00106282440.018
regulation of phosphorylationGO:00423252480.018
ras protein signal transductionGO:0007265290.018
cell projection organizationGO:00300303020.018
reactive nitrogen species metabolic processGO:200105710.018
oxoacid metabolic processGO:00434362900.017
amine metabolic processGO:0009308380.017
response to nutrient levelsGO:00316673700.017
negative regulation of gene expressionGO:00106291990.017
immune system developmentGO:0002520410.017
Human
t cell receptor signaling pathwayGO:005085210.017
metal ion homeostasisGO:00550651860.017
axis specificationGO:000979840.017
regulation of reactive oxygen species biosynthetic processGO:190342650.017
t cell differentiationGO:003021790.017
Human
protein complex subunit organizationGO:00718223020.017
carboxylic acid metabolic processGO:00197522890.017
regulation of cellular ketone metabolic processGO:0010565270.017
organophosphate metabolic processGO:00196373700.017
locomotionGO:00400112370.016
Zebrafish
regulation of cell developmentGO:00602842630.016
purine containing compound metabolic processGO:00725212530.016
cellular response to oxidative stressGO:0034599760.016
cellular response to external stimulusGO:00714961180.016
intracellular transportGO:00469071850.016
Rat
cellular ion homeostasisGO:00068731840.016
nucleic acid templated transcriptionGO:00976593790.016
regulation of cellular amine metabolic processGO:003323880.016
positive regulation of neurogenesisGO:00507691650.016
cell morphogenesisGO:00009021420.016
inflammatory response to antigenic stimulusGO:0002437180.016
cellular response to organic cyclic compoundGO:00714072020.016
proteolysisGO:00065081750.016
regulation of response to stressGO:00801341260.015
cellular ketone metabolic processGO:0042180510.015
response to purine containing compoundGO:00140741260.015
regulation of cell differentiationGO:00455953200.015
Human
lymphoid progenitor cell differentiationGO:000232020.015
negative regulation of rna metabolic processGO:00512531230.015
cell type specific apoptotic processGO:00972851340.015
positive regulation of phosphate metabolic processGO:00459372620.015
single organism cell adhesionGO:0098602460.015
transmembrane transportGO:00550854120.015
positive regulation of natural killer cell mediated cytotoxicityGO:004595420.015
regulation of protein metabolic processGO:00512462890.015
cellular response to endogenous stimulusGO:00714953770.015
divalent inorganic cation transportGO:00725111340.015
cell migrationGO:00164771970.015
Zebrafish
protein complex assemblyGO:00064612630.015
small gtpase mediated signal transductionGO:0007264360.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
cellular response to hormone stimulusGO:00328702470.014
negative regulation of response to stimulusGO:00485851550.014
tissue remodelingGO:0048771400.014
multi organism reproductive processGO:00447032620.014
nucleoside phosphate metabolic processGO:00067532830.014
chemical homeostasisGO:00488782920.014
regulation of t cell activationGO:0050863230.014
Human
regulation of metal ion transportGO:00109591180.014
regulation of protein phosphorylationGO:00019321830.014
agingGO:00075682410.014
single organism catabolic processGO:00447122830.014
cellular amino acid metabolic processGO:00065201070.014
multicellular organismal reproductive processGO:00486092330.014
positive regulation of catalytic activityGO:00430851840.014
cellular catabolic processGO:00442482950.014
heterocycle catabolic processGO:00467001670.014
cellular response to cytokine stimulusGO:00713451270.014
regulation of hydrolase activityGO:00513361430.013
calcium ion transportGO:00068161310.013
macromolecular complex assemblyGO:00650032730.013
cellular nitrogen compound catabolic processGO:00442701630.013
positive regulation of programmed cell deathGO:00430681570.013
cell motilityGO:00488702020.013
Zebrafish
ribose phosphate metabolic processGO:00196932350.013
neuron developmentGO:00486662860.013
regulation of nervous system developmentGO:00519602640.013
cell chemotaxisGO:0060326310.013
cell killingGO:0001906130.013
cellular component movementGO:00069282480.013
Zebrafish
positive regulation of multicellular organismal processGO:00512403870.013
Human Zebrafish
response to hydrogen peroxideGO:0042542890.013
spindle organizationGO:000705120.013
regulation of apoptotic processGO:00429813350.013
establishment of protein localizationGO:00451841410.013
cellular component morphogenesisGO:00329891550.013
response to peptide hormoneGO:00434342780.013
chemosensory behaviorGO:000763520.013
response to transition metal nanoparticleGO:19902671220.013
cytoplasmic transportGO:00164821150.013
negative regulation of programmed cell deathGO:00430691830.013
reproductive structure developmentGO:00486081280.013
macromolecule localizationGO:00330362520.013
reproductive processGO:00224143720.013
olfactory behaviorGO:004204820.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
tube formationGO:003514830.013
response to woundingGO:00096112540.012
catabolic processGO:00090563510.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
chemotaxisGO:0006935660.012
nucleotide metabolic processGO:00091172790.012
organophosphate biosynthetic processGO:00904071430.012
regulation of homeostatic processGO:00328441010.012
olfactory learningGO:000835510.012
organonitrogen compound catabolic processGO:19015651790.012
cell cycleGO:00070491010.012
cell projection morphogenesisGO:00488581230.012
carbohydrate derivative metabolic processGO:19011353460.012
purine nucleoside metabolic processGO:00422781690.012
lymphocyte migrationGO:007267630.012
g protein coupled receptor signaling pathwayGO:00071862420.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
regulation of phosphate metabolic processGO:00192203490.012
nucleoside metabolic processGO:00091161790.012
negative regulation of leukocyte apoptotic processGO:200010740.012
negative regulation of catalytic activityGO:00430861030.012
regulation of neuron deathGO:19012141150.012
cellular response to molecule of fungal originGO:007122610.012
lipid metabolic processGO:00066292830.012
positive regulation of necroptotic processGO:006054520.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
cellular response to growth factor stimulusGO:00713631620.012
growthGO:00400071650.012
taxisGO:0042330670.012
sequestering of metal ionGO:005123890.012
nucleobase containing compound catabolic processGO:00346551520.011
cellular response to oxygen containing compoundGO:19017013860.011
negative regulation of cellular biosynthetic processGO:00313271610.011
mapk cascadeGO:00001651400.011
regulation of cellular component movementGO:00512701500.011
Zebrafish
positive regulation of protein metabolic processGO:00512471780.011
dna metabolic processGO:0006259960.011
antigen receptor mediated signaling pathwayGO:005085110.011
negative regulation of neuron deathGO:1901215690.011
positive regulation of neuron differentiationGO:00456661260.011
chromosome segregationGO:000705920.011
rho protein signal transductionGO:0007266110.011
biological adhesionGO:00226101100.011
positive regulation of cell differentiationGO:00455972170.011
Human
negative regulation of transcription dna templatedGO:00458921160.011
anatomical structure morphogenesisGO:00096532980.011
Zebrafish
cellular response to extracellular stimulusGO:0031668730.011
reactive oxygen species metabolic processGO:0072593370.011
reproductionGO:00000032450.011
regulation of interferon gamma productionGO:003264930.011
organonitrogen compound biosynthetic processGO:19015661670.011
purine ribonucleotide metabolic processGO:00091502270.011
negative regulation of protein metabolic processGO:00512481140.011
nitrogen compound transportGO:00717052290.011
positive regulation of natural killer cell mediated immunityGO:000271720.011
purine nucleotide metabolic processGO:00061632290.011
response to lipopolysaccharideGO:00324961910.011
salivary gland developmentGO:000743130.011
positive regulation of protein modification processGO:00314011420.011
protein oligomerizationGO:00512591910.011
regenerationGO:00310991630.011
gastrulationGO:000736920.011
mast cell migrationGO:009753140.011
gland developmentGO:00487321550.011
cardiovascular system developmentGO:00723581340.011
Zebrafish
regulation of cellular component organizationGO:00511283680.010
epithelial cell differentiationGO:0030855710.010
lipid storageGO:001991510.010
negative regulation of cellular protein metabolic processGO:00322691060.010
head developmentGO:00603222470.010
tube developmentGO:0035295890.010
positive regulation of cell deathGO:00109421840.010
alpha beta t cell differentiationGO:004663220.010
organic cyclic compound catabolic processGO:19013611750.010
cell adhesionGO:00071551100.010
cellular lipid metabolic processGO:00442552080.010
leukocyte migrationGO:0050900380.010
regulation of stem cell differentiationGO:200073620.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
positive regulation of signalingGO:00230562700.010

Zap70 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
musculoskeletal system diseaseDOID:1700.019
connective tissue diseaseDOID:6500.019
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011