Rattus norvegicus

0 known processes

Impact

imprinted and ancient

Impact biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442552080.217
macromolecular complex subunit organizationGO:00439333390.178
intracellular signal transductionGO:00355563140.173
protein phosphorylationGO:00064683450.145
rna metabolic processGO:00160704060.141
cellular response to hormone stimulusGO:00328702470.140
regulation of molecular functionGO:00650093980.139
regulation of rna biosynthetic processGO:20011413810.131
regulation of phosphorus metabolic processGO:00511743490.123
reproductive processGO:00224143720.115
regulation of phosphorylationGO:00423252480.115
regulation of phosphate metabolic processGO:00192203490.108
regulation of rna metabolic processGO:00512523910.107
macromolecular complex assemblyGO:00650032730.105
cellular component assemblyGO:00226073600.103
negative regulation of metabolic processGO:00098923310.097
organic acid metabolic processGO:00060822920.095
programmed cell deathGO:00125013920.095
cellular protein localizationGO:00346131220.093
regulation of nucleic acid templated transcriptionGO:19035063800.091
developmental process involved in reproductionGO:00030061590.088
single organism reproductive processGO:00447022970.086
reproductive structure developmentGO:00486081280.084
cation transportGO:00068123820.084
multicellular organismal reproductive processGO:00486092330.083
regulation of system processGO:00440572080.083
mapk cascadeGO:00001651400.081
positive regulation of nitrogen compound metabolic processGO:00511733340.077
apoptotic processGO:00069153810.075
transmembrane transportGO:00550854120.075
cell projection organizationGO:00300303020.074
cellular response to oxygen containing compoundGO:19017013860.074
signal transduction by phosphorylationGO:00230141440.069
neuron developmentGO:00486662860.068
nucleic acid templated transcriptionGO:00976593790.068
positive regulation of phosphorylationGO:00423271770.067
cellular amino acid metabolic processGO:00065201070.065
regulation of protein metabolic processGO:00512462890.064
multicellular organism reproductionGO:00325042330.064
organophosphate metabolic processGO:00196373700.059
single organism biosynthetic processGO:00447113420.059
cellular component biogenesisGO:00440853680.058
response to estrogenGO:00436272320.057
positive regulation of nucleobase containing compound metabolic processGO:00459353190.056
regulation of protein modification processGO:00313991940.056
tube developmentGO:0035295890.055
macromolecule localizationGO:00330362520.055
positive regulation of phosphate metabolic processGO:00459372620.055
protein complex subunit organizationGO:00718223020.055
cellular response to endogenous stimulusGO:00714953770.055
protein complex assemblyGO:00064612630.054
regulation of neuron apoptotic processGO:0043523830.054
response to nutrient levelsGO:00316673700.054
growthGO:00400071650.053
regulation of transcription dna templatedGO:00063553740.053
regulation of cellular protein metabolic processGO:00322682670.053
anion transportGO:00068201780.052
reproductionGO:00000032450.051
negative regulation of neuron apoptotic processGO:0043524450.051
reproductive system developmentGO:00614581280.050
regulation of transferase activityGO:00513381230.050
neuron apoptotic processGO:0051402880.049
cellular component movementGO:00069282480.049
cellular response to organic cyclic compoundGO:00714072020.048
negative regulation of cellular metabolic processGO:00313242810.047
cellular macromolecule localizationGO:00707271220.047
lipid metabolic processGO:00066292830.046
negative regulation of macromolecule metabolic processGO:00106052600.046
regulation of cell developmentGO:00602842630.045
female gonad developmentGO:0008585530.045
positive regulation of protein modification processGO:00314011420.045
g protein coupled receptor signaling pathwayGO:00071862420.044
response to metal ionGO:00100382530.044
regulation of transcription from rna polymerase ii promoterGO:00063572340.044
establishment of protein localizationGO:00451841410.043
organelle organizationGO:00069962660.043
oxoacid metabolic processGO:00434362900.043
positive regulation of protein metabolic processGO:00512471780.043
response to inorganic substanceGO:00100353770.043
purine containing compound metabolic processGO:00725212530.042
nucleotide metabolic processGO:00091172790.042
regulation of signal transductionGO:00099663180.041
positive regulation of developmental processGO:00510942830.041
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.041
response to glucocorticoidGO:00513842230.041
cellular response to glucocorticoid stimulusGO:0071385680.041
carboxylic acid metabolic processGO:00197522890.041
nucleoside phosphate metabolic processGO:00067532830.041
transcription from rna polymerase ii promoterGO:00063662520.040
protein oligomerizationGO:00512591910.040
amine metabolic processGO:0009308380.040
regulation of programmed cell deathGO:00430673410.040
cellular amine metabolic processGO:0044106380.040
positive regulation of catalytic activityGO:00430851840.040
regulation of secretionGO:00510462240.039
rna biosynthetic processGO:00327743800.039
cellular ketone metabolic processGO:0042180510.039
muscle system processGO:00030121150.039
nucleobase containing small molecule metabolic processGO:00550863160.038
inflammatory responseGO:00069541500.038
rhythmic processGO:00485111560.037
purine nucleotide metabolic processGO:00061632290.037
dna metabolic processGO:0006259960.036
response to estradiolGO:00323551640.036
positive regulation of cellular protein metabolic processGO:00322701670.036
inorganic ion transmembrane transportGO:00986602290.036
negative regulation of nitrogen compound metabolic processGO:00511721610.036
regulation of catalytic activityGO:00507903040.036
muscle contractionGO:0006936880.035
cellular response to lipidGO:00713962010.035
positive regulation of cytosolic calcium ion concentrationGO:00072041220.035
cytoskeleton organizationGO:00070101110.035
negative regulation of cell deathGO:00605482290.034
response to dexamethasoneGO:0071548490.034
response to cytokineGO:00340972150.034
intracellular transportGO:00469071850.034
carbohydrate derivative metabolic processGO:19011353460.034
blood circulationGO:00080151830.033
gonad developmentGO:00084061040.033
homeostatic processGO:00425923310.032
multi organism reproductive processGO:00447032620.032
ribose phosphate metabolic processGO:00196932350.032
negative regulation of cellular protein metabolic processGO:00322691060.032
single organism intracellular transportGO:19025821660.032
response to ketoneGO:19016541820.032
chemical homeostasisGO:00488782920.032
cation homeostasisGO:00550801950.032
response to extracellular stimulusGO:00099913800.032
regulation of apoptotic processGO:00429813350.032
regulation of cellular component organizationGO:00511283680.032
regulation of cellular amino acid metabolic processGO:000652120.032
calcium ion transportGO:00068161310.032
cellular divalent inorganic cation homeostasisGO:00725031620.032
wnt signaling pathway planar cell polarity pathwayGO:006007120.032
regulation of body fluid levelsGO:0050878900.031
response to heatGO:0009408600.031
metal ion homeostasisGO:00550651860.031
regulation of cellular component biogenesisGO:0044087860.031
positive regulation of synaptic transmissionGO:0050806620.031
cellular response to stressGO:00335542690.031
divalent inorganic cation homeostasisGO:00725071650.031
wound healingGO:00420601220.031
development of primary sexual characteristicsGO:00451371070.031
cellular response to nitrogen compoundGO:19016992100.030
single organism organelle organizationGO:19025891800.030
second messenger mediated signalingGO:0019932510.030
sex differentiationGO:00075481130.030
metal ion transportGO:00300012890.030
transcription dna templatedGO:00063513770.029
cellular component morphogenesisGO:00329891550.029
positive regulation of transcription dna templatedGO:00458931970.029
cellular response to steroid hormone stimulusGO:0071383930.029
response to woundingGO:00096112540.028
regulation of nervous system developmentGO:00519602640.028
cellular cation homeostasisGO:00300031800.028
cellular response to growth factor stimulusGO:00713631620.028
neuron deathGO:00709971270.028
ras protein signal transductionGO:0007265290.028
development of primary female sexual characteristicsGO:0046545560.028
cellular ion homeostasisGO:00068731840.028
regulation of neuron deathGO:19012141150.028
phospholipid metabolic processGO:0006644610.027
positive regulation of biosynthetic processGO:00098913190.027
neuron differentiationGO:00301823680.027
positive regulation of cell developmentGO:00107201760.027
protein transportGO:00150311320.027
positive regulation of cellular component organizationGO:00511302000.026
inorganic cation transmembrane transportGO:00986622020.026
regulation of protein kinase activityGO:00458591050.026
regenerationGO:00310991630.026
neurological system processGO:00508772190.026
positive regulation of intracellular signal transductionGO:19025331380.026
negative regulation of apoptotic processGO:00430661810.026
positive regulation of nucleotide metabolic processGO:0045981910.026
response to other organismGO:00517072200.026
regulation of cellular ketone metabolic processGO:0010565270.026
regulation of cell differentiationGO:00455953200.026
ribonucleotide metabolic processGO:00092592310.025
cell cell signalingGO:00072673350.025
protein localizationGO:00081041910.025
cellular macromolecular complex assemblyGO:0034622580.025
female sex differentiationGO:0046660590.025
protein complex biogenesisGO:00702712630.025
positive regulation of protein phosphorylationGO:00019341350.025
positive regulation of gene expressionGO:00106282440.025
cell type specific apoptotic processGO:00972851340.024
purine ribonucleoside metabolic processGO:00461281680.024
regulation of membrane potentialGO:00423911100.024
regulation of cell projection organizationGO:00313441750.024
cell motilityGO:00488702020.024
positive regulation of molecular functionGO:00440932300.024
circulatory system developmentGO:00723591340.024
organic acid transportGO:00158491160.024
sexual reproductionGO:00199531480.024
synaptic growth at neuromuscular junctionGO:005112410.024
purine containing compound biosynthetic processGO:0072522850.023
negative regulation of protein metabolic processGO:00512481140.023
cellular response to organonitrogen compoundGO:00714171970.023
positive regulation of response to stimulusGO:00485842850.023
regulation of cellular amine metabolic processGO:003323880.023
calcium ion homeostasisGO:00550741620.023
neuron projection developmentGO:00311752730.023
axis specificationGO:000979840.022
negative regulation of neuron deathGO:1901215690.022
localization of cellGO:00516742020.022
response to oxidative stressGO:00069791860.022
regulation of homeostatic processGO:00328441010.022
secretionGO:00469033070.022
regulation of smooth muscle cell proliferationGO:0048660750.022
ion homeostasisGO:00508012120.022
catabolic processGO:00090563510.022
negative regulation of multicellular organismal processGO:00512412030.022
cell cycleGO:00070491010.021
negative regulation of transportGO:00510511360.021
peptidyl amino acid modificationGO:00181931260.021
leukocyte cell cell adhesionGO:000715940.021
regulation of ion transportGO:00432692450.021
positive regulation of cell differentiationGO:00455972170.021
positive regulation of cell projection organizationGO:00313461110.021
cellular metal ion homeostasisGO:00068751720.021
response to external biotic stimulusGO:00432072210.021
cell migrationGO:00164771970.020
cellular nitrogen compound catabolic processGO:00442701630.020
cytoplasmic transportGO:00164821150.020
response to lipopolysaccharideGO:00324961910.020
ion transmembrane transportGO:00342203650.020
small gtpase mediated signal transductionGO:0007264360.020
response to radiationGO:00093141370.020
cell part morphogenesisGO:00329901230.020
cellular chemical homeostasisGO:00550822470.020
response to corticosteroidGO:00319602350.020
divalent inorganic cation transportGO:00725111340.020
single organism catabolic processGO:00447122830.020
response to peptideGO:19016522920.020
cellular calcium ion homeostasisGO:00068741600.019
neuron projection morphogenesisGO:00488121220.019
organonitrogen compound biosynthetic processGO:19015661670.019
cellular response to external stimulusGO:00714961180.019
muscle cell proliferationGO:0033002840.019
regulation of intracellular signal transductionGO:19025312180.019
response to hypoxiaGO:00016662310.019
positive regulation of cellular biosynthetic processGO:00313282950.019
regulation of protein phosphorylationGO:00019321830.019
positive regulation of secretion by cellGO:19035321280.019
protein homooligomerizationGO:0051260910.019
response to insulinGO:00328681330.019
carboxylic acid transportGO:00469421150.018
positive regulation of purine nucleotide metabolic processGO:1900544910.018
response to molecule of bacterial originGO:00022371940.018
membrane organizationGO:0061024940.018
single organism behaviorGO:00447081300.018
hormone secretionGO:00468791150.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
negative regulation of signalingGO:00230571570.018
positive regulation of rna metabolic processGO:00512542030.018
regulation of mapk cascadeGO:00434081160.018
regulation of metal ion transportGO:00109591180.018
positive regulation of secretionGO:00510471400.018
positive regulation of organelle organizationGO:0010638480.018
secretion by cellGO:00329402480.018
organ regenerationGO:00311001010.018
positive regulation of rna biosynthetic processGO:19026801970.018
organic substance catabolic processGO:19015753160.018
oxidation reduction processGO:00551143040.018
locomotionGO:00400112370.018
regulation of nucleotide metabolic processGO:00061401170.017
non canonical wnt signaling pathwayGO:003556730.017
cell projection morphogenesisGO:00488581230.017
response to fibroblast growth factorGO:0071774290.017
positive regulation of signalingGO:00230562700.017
synaptic transmissionGO:00072682350.017
actin filament based processGO:0030029860.017
spindle organizationGO:000705120.017
negative regulation of gene expressionGO:00106291990.017
sequestering of metal ionGO:005123890.017
regulation of synaptic transmissionGO:00508041410.017
regulation of multicellular organismal developmentGO:20000263760.017
regulation of cellular catabolic processGO:00313291010.017
response to temperature stimulusGO:0009266940.017
male sex differentiationGO:0046661640.016
regulation of lipid metabolic processGO:0019216680.016
regulation of ion transmembrane transportGO:00347651210.016
calcium ion transmembrane transportGO:0070588700.016
regulation of anatomical structure sizeGO:00900661350.016
positive regulation of blood circulationGO:1903524650.016
regulation of respiratory gaseous exchangeGO:004357620.016
retinal metabolic processGO:004257430.016
cardiovascular system developmentGO:00723581340.016
agingGO:00075682410.016
rho protein signal transductionGO:0007266110.016
gastrulationGO:000736920.016
reactive nitrogen species metabolic processGO:200105710.016
neurotransmitter gated ion channel clusteringGO:007257830.016
positive regulation of multicellular organismal processGO:00512403870.016
purine ribonucleotide metabolic processGO:00091502270.016
anatomical structure morphogenesisGO:00096532980.015
sequestering of calcium ionGO:005120880.015
circadian rhythmGO:0007623880.015
positive regulation of cellular component movementGO:00512721020.015
organonitrogen compound catabolic processGO:19015651790.015
regulation of calcium ion transportGO:0051924770.015
response to biotic stimulusGO:00096072260.015
cellular homeostasisGO:00197252520.015
response to luteinizing hormoneGO:003469950.015
digestive tract developmentGO:0048565390.015
response to reactive oxygen speciesGO:00003021200.015
defense responseGO:00069521940.015
organophosphate catabolic processGO:00464341480.015
lipid biosynthetic processGO:00086101280.015
generation of precursor metabolites and energyGO:0006091620.015
regulation of sodium ion transmembrane transporter activityGO:200064940.015
positive regulation of cell communicationGO:00106472710.015
organophosphate biosynthetic processGO:00904071430.015
regulation of catabolic processGO:00098941130.015
negative regulation of programmed cell deathGO:00430691830.015
neuron neuron synaptic transmissionGO:0007270600.015
taxisGO:0042330670.014
chromosome organizationGO:0051276360.014
jnk cascadeGO:0007254280.014
regulation of map kinase activityGO:0043405530.014
regulation of cell cycleGO:0051726730.014
regulation of response to stressGO:00801341260.014
regulation of cell motilityGO:20001451310.014
ribose phosphate biosynthetic processGO:0046390870.014
positive regulation of neuron projection developmentGO:0010976990.014
regulation of purine nucleotide metabolic processGO:19005421150.014
cellular protein complex assemblyGO:0043623440.014
regulation of hydrolase activityGO:00513361430.014
positive regulation of cellular amine metabolic processGO:003324030.014
cell morphogenesisGO:00009021420.014
circadian sleep wake cycleGO:0042745230.014
response to vitaminGO:00332731310.014
protein tetramerizationGO:0051262380.014
reactive oxygen species metabolic processGO:0072593370.014
cell growthGO:00160491040.014
multi multicellular organism processGO:00447061380.013
signal releaseGO:00230611450.013
gamete generationGO:00072761240.013
cellular response to alcoholGO:0097306870.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
reactive oxygen species biosynthetic processGO:190340980.013
chromatin organizationGO:0006325340.013
regulation of neuron differentiationGO:00456642080.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
regulation of transmembrane transportGO:00347621220.013
cytosolic calcium ion homeostasisGO:00514801400.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
protein autophosphorylationGO:0046777660.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
nitrogen compound transportGO:00717052290.013
cellular response to nutrient levelsGO:0031669600.013
striated muscle contractionGO:0006941440.013
circulatory system processGO:00030131830.013
regulation of ion transmembrane transporter activityGO:0032412480.013
cell morphogenesis involved in differentiationGO:00009041190.013
response to nutrientGO:00075842480.013
negative regulation of rna metabolic processGO:00512531230.012
cell cycle checkpointGO:000007520.012
maintenance of locationGO:0051235170.012
regulation of neurogenesisGO:00507672470.012
positive regulation of phosphorus metabolic processGO:00105622620.012
negative regulation of cell communicationGO:00106481580.012
single organism membrane organizationGO:0044802740.012
regulation of nucleotide catabolic processGO:0030811650.012
epithelium developmentGO:0060429960.012
response to light stimulusGO:0009416520.012
nucleoside phosphate biosynthetic processGO:19012931020.012
response to hexoseGO:00097461440.012
response to decreased oxygen levelsGO:00362932370.012
regulation of cell proliferationGO:00421273590.012
positive regulation of protein serine threonine kinase activityGO:0071902520.012
negative regulation of biosynthetic processGO:00098901680.012
dna replicationGO:0006260370.012
cell adhesionGO:00071551100.012
carbohydrate derivative biosynthetic processGO:19011371240.012
nucleoside phosphate catabolic processGO:19012921400.012
regulation of blood vessel sizeGO:0050880890.012
regulation of actin filament based processGO:0032970420.012
negative regulation of molecular functionGO:00440921330.012
multicellular organismal homeostasisGO:0048871490.012
nucleotide catabolic processGO:00091661390.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
male gamete generationGO:0048232990.012
regulation of erk1 and erk2 cascadeGO:0070372410.012
negative regulation of macromolecule biosynthetic processGO:00105581480.011
ribonucleotide biosynthetic processGO:0009260850.011
development of primary male sexual characteristicsGO:0046546590.011
female pregnancyGO:00075651220.011
regulation of neuron projection developmentGO:00109751610.011
lipid localizationGO:0010876620.011
positive regulation of neurogenesisGO:00507691650.011
cellular response to peptideGO:19016531330.011
lipid transportGO:0006869610.011
negative regulation of rna biosynthetic processGO:19026791180.011
regulation of organelle organizationGO:0033043800.011
response to oxygen levelsGO:00704822650.011
behaviorGO:00076102050.011
negative regulation of cellular biosynthetic processGO:00313271610.011
positive regulation of cell proliferationGO:00082842490.011
regulation of synaptic transmission glutamatergicGO:0051966260.011
divalent metal ion transportGO:00708381320.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
single organism cell adhesionGO:0098602460.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
purine nucleotide biosynthetic processGO:0006164830.011
ribonucleotide catabolic processGO:00092611360.011
monocarboxylic acid metabolic processGO:00327871520.011
protein targetingGO:0006605610.011
organic hydroxy compound metabolic processGO:19016151150.011
positive regulation of cellular catabolic processGO:0031331710.011
response to toxic substanceGO:00096361330.011
cellular response to carbohydrate stimulusGO:0071322720.010
small molecule biosynthetic processGO:00442831240.010
response to amino acidGO:0043200750.010
intracellular protein transportGO:0006886790.010
feeding behaviorGO:0007631530.010
respiratory gaseous exchangeGO:000758540.010
positive regulation of dna metabolic processGO:0051054390.010
regulation of intracellular transportGO:0032386650.010
purine containing compound catabolic processGO:00725231380.010
exploration behaviorGO:003564010.010
positive regulation of reactive oxygen species metabolic processGO:2000379160.010
nucleobase containing compound catabolic processGO:00346551520.010
lipid storageGO:001991510.010
regulation of canonical wnt signaling pathwayGO:006082840.010
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.010
cellular respirationGO:0045333210.010
positive regulation of macromolecule biosynthetic processGO:00105572470.010
nucleoside triphosphate catabolic processGO:00091431230.010
dna integrity checkpointGO:003157020.010
developmental maturationGO:0021700250.010
response to ethanolGO:00454711620.010
potassium ion transportGO:0006813970.010
positive regulation of cytoskeleton organizationGO:0051495260.010
regulation of mrna splicing via spliceosomeGO:004802430.010

Impact disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
nervous system diseaseDOID:86300.032
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
central nervous system diseaseDOID:33100.017
musculoskeletal system diseaseDOID:1700.016
organ system cancerDOID:005068600.013
sensory system diseaseDOID:005015500.013