Rattus norvegicus

183 known processes

Alox12

arachidonate 12-lipoxygenase

(Aliases: MGC187960)

Alox12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to extracellular stimulusGO:00099913800.130
Rat
organic acid metabolic processGO:00060822920.113
carboxylic acid metabolic processGO:00197522890.105
regulation of protein metabolic processGO:00512462890.099
protein phosphorylationGO:00064683450.094
response to oxygen levelsGO:00704822650.093
Rat
intracellular signal transductionGO:00355563140.091
regulation of multicellular organismal developmentGO:20000263760.089
cellular amino acid metabolic processGO:00065201070.082
apoptotic processGO:00069153810.081
regulation of apoptotic processGO:00429813350.078
regulation of rna metabolic processGO:00512523910.078
cellular component assemblyGO:00226073600.075
regulation of catalytic activityGO:00507903040.074
homeostatic processGO:00425923310.072
positive regulation of response to stimulusGO:00485842850.072
response to woundingGO:00096112540.071
amine metabolic processGO:0009308380.071
response to inorganic substanceGO:00100353770.071
negative regulation of apoptotic processGO:00430661810.069
anatomical structure morphogenesisGO:00096532980.068
Human
regulation of programmed cell deathGO:00430673410.065
regulation of phosphate metabolic processGO:00192203490.064
cellular response to oxygen containing compoundGO:19017013860.064
response to decreased oxygen levelsGO:00362932370.063
localization of cellGO:00516742020.063
regulation of signal transductionGO:00099663180.062
metal ion transportGO:00300012890.062
response to nutrient levelsGO:00316673700.061
Rat
cellular amine metabolic processGO:0044106380.057
regulation of cell proliferationGO:00421273590.057
monovalent inorganic cation transportGO:00156721720.057
positive regulation of signalingGO:00230562700.057
transmembrane transportGO:00550854120.057
regulation of cellular amine metabolic processGO:003323880.055
cellular homeostasisGO:00197252520.052
single organism reproductive processGO:00447022970.052
tissue developmentGO:00098882520.050
regulation of cellular component organizationGO:00511283680.049
Human
rna metabolic processGO:00160704060.048
regulation of cell differentiationGO:00455953200.048
gland developmentGO:00487321550.048
negative regulation of multicellular organismal processGO:00512412030.048
protein complex subunit organizationGO:00718223020.047
inorganic ion transmembrane transportGO:00986602290.047
cellular component biogenesisGO:00440853680.047
positive regulation of cell proliferationGO:00082842490.046
macromolecule localizationGO:00330362520.045
regulation of cellular amino acid metabolic processGO:000652120.045
negative regulation of metabolic processGO:00098923310.045
macromolecular complex subunit organizationGO:00439333390.045
response to hypoxiaGO:00016662310.044
cellular response to growth factor stimulusGO:00713631620.044
oxoacid metabolic processGO:00434362900.044
regulation of cellular ketone metabolic processGO:0010565270.044
regulation of cell migrationGO:00303341280.044
positive regulation of cell communicationGO:00106472710.043
nucleic acid templated transcriptionGO:00976593790.043
regulation of cellular protein metabolic processGO:00322682670.043
regulation of cellular component movementGO:00512701500.043
positive regulation of nitrogen compound metabolic processGO:00511733340.043
programmed cell deathGO:00125013920.043
behaviorGO:00076102050.042
regulation of hydrolase activityGO:00513361430.042
organic substance catabolic processGO:19015753160.041
response to carbohydrateGO:00097431830.041
cellular ketone metabolic processGO:0042180510.041
single organism behaviorGO:00447081300.041
cation transportGO:00068123820.040
positive regulation of cellular protein metabolic processGO:00322701670.040
rhythmic processGO:00485111560.040
regulation of nucleic acid templated transcriptionGO:19035063800.039
positive regulation of cellular amino acid metabolic processGO:004576410.039
growthGO:00400071650.039
Human
cell cell signalingGO:00072673350.038
cellular catabolic processGO:00442482950.038
negative regulation of programmed cell deathGO:00430691830.038
purine containing compound catabolic processGO:00725231380.037
wound healingGO:00420601220.037
nucleobase containing small molecule metabolic processGO:00550863160.037
positive regulation of developmental processGO:00510942830.037
response to growth factorGO:00708481890.036
peptidyl amino acid modificationGO:00181931260.036
positive regulation of cellular component organizationGO:00511302000.036
anion transmembrane transportGO:0098656770.036
ion transmembrane transportGO:00342203650.036
cellular response to endogenous stimulusGO:00714953770.036
regulation of body fluid levelsGO:0050878900.036
single organism organelle organizationGO:19025891800.036
renal system developmentGO:0072001670.035
multi organism reproductive processGO:00447032620.035
transcription dna templatedGO:00063513770.034
response to peptide hormoneGO:00434342780.034
regulation of molecular functionGO:00650093980.034
negative regulation of developmental processGO:00510931250.034
single organism biosynthetic processGO:00447113420.033
response to oxidative stressGO:00069791860.033
secretion by cellGO:00329402480.033
protein oligomerizationGO:00512591910.032
chemical homeostasisGO:00488782920.032
macromolecular complex assemblyGO:00650032730.032
response to metal ionGO:00100382530.032
regulation of protein modification processGO:00313991940.032
regulation of cell projection organizationGO:00313441750.032
carboxylic acid biosynthetic processGO:0046394830.031
negative regulation of macromolecule metabolic processGO:00106052600.031
positive regulation of multicellular organismal processGO:00512403870.031
single organism catabolic processGO:00447122830.031
positive regulation of biosynthetic processGO:00098913190.031
negative regulation of cell deathGO:00605482290.031
protein localizationGO:00081041910.031
kidney developmentGO:0001822670.030
reproductive processGO:00224143720.030
protein complex assemblyGO:00064612630.030
positive regulation of protein metabolic processGO:00512471780.030
response to monosaccharideGO:00342841590.030
neuron differentiationGO:00301823680.030
response to peptideGO:19016522920.029
ribonucleoside metabolic processGO:00091191740.029
response to lipopolysaccharideGO:00324961910.029
brain developmentGO:00074202470.029
cellular component movementGO:00069282480.029
response to bacteriumGO:00096172000.029
response to acid chemicalGO:00011012220.029
positive regulation of programmed cell deathGO:00430681570.029
regulation of transcription dna templatedGO:00063553740.029
rna biosynthetic processGO:00327743800.028
positive regulation of cell differentiationGO:00455972170.028
cellular chemical homeostasisGO:00550822470.028
cellular response to stressGO:00335542690.028
female pregnancyGO:00075651220.028
organophosphate metabolic processGO:00196373700.028
response to cytokineGO:00340972150.028
response to organophosphorusGO:00466831020.028
ras protein signal transductionGO:0007265290.027
carbohydrate derivative catabolic processGO:19011361470.027
urogenital system developmentGO:0001655780.027
regulation of nervous system developmentGO:00519602640.027
cell migrationGO:00164771970.027
positive regulation of protein phosphorylationGO:00019341350.027
neuron projection developmentGO:00311752730.027
positive regulation of cellular amine metabolic processGO:003324030.027
protein complex biogenesisGO:00702712630.026
glycosyl compound metabolic processGO:19016571820.026
positive regulation of cellular component movementGO:00512721020.026
positive regulation of cellular biosynthetic processGO:00313282950.026
regulation of phosphorus metabolic processGO:00511743490.026
ribonucleotide catabolic processGO:00092611360.026
positive regulation of phosphorus metabolic processGO:00105622620.026
response to hexoseGO:00097461440.026
response to molecule of bacterial originGO:00022371940.026
cellular nitrogen compound catabolic processGO:00442701630.026
actin filament based processGO:0030029860.026
nucleoside phosphate catabolic processGO:19012921400.025
nucleotide metabolic processGO:00091172790.025
purine nucleotide catabolic processGO:00061951360.025
hormone secretionGO:00468791150.025
positive regulation of molecular functionGO:00440932300.025
response to purine containing compoundGO:00140741260.025
ossificationGO:0001503700.024
nucleoside metabolic processGO:00091161790.024
organonitrogen compound catabolic processGO:19015651790.024
positive regulation of cell developmentGO:00107201760.024
positive regulation of catalytic activityGO:00430851840.024
negative regulation of cell proliferationGO:00082851190.024
ion homeostasisGO:00508012120.024
transcription from rna polymerase ii promoterGO:00063662520.024
nitrogen compound transportGO:00717052290.024
positive regulation of rna metabolic processGO:00512542030.024
response to estrogenGO:00436272320.024
cellular ion homeostasisGO:00068731840.024
regulation of cell developmentGO:00602842630.023
nucleoside phosphate metabolic processGO:00067532830.023
positive regulation of cell deathGO:00109421840.023
organ regenerationGO:00311001010.023
protein homooligomerizationGO:0051260910.023
b cell mediated immunityGO:001972440.023
cellular metal ion homeostasisGO:00068751720.023
purine nucleoside metabolic processGO:00422781690.023
defense responseGO:00069521940.023
Rat
sensory organ developmentGO:0007423740.023
positive regulation of protein modification processGO:00314011420.023
negative regulation of cell communicationGO:00106481580.023
regulation of neurogenesisGO:00507672470.023
regulation of cell motilityGO:20001451310.023
g protein coupled receptor signaling pathwayGO:00071862420.023
response to mechanical stimulusGO:00096121340.022
regulation of anatomical structure morphogenesisGO:00226031410.022
Human
cellular component morphogenesisGO:00329891550.022
nucleobase containing compound catabolic processGO:00346551520.022
peptidyl tyrosine modificationGO:0018212720.022
membrane organizationGO:0061024940.022
cellular response to organonitrogen compoundGO:00714171970.022
purine ribonucleotide catabolic processGO:00091541360.022
cell adhesionGO:00071551100.021
Human Rat
organophosphate catabolic processGO:00464341480.021
regulation of catabolic processGO:00098941130.021
regulation of cell morphogenesis involved in differentiationGO:0010769720.021
small gtpase mediated signal transductionGO:0007264360.021
circadian rhythmGO:0007623880.021
regulation of neuron differentiationGO:00456642080.021
organelle organizationGO:00069962660.021
regulation of intracellular signal transductionGO:19025312180.020
multicellular organism reproductionGO:00325042330.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
aromatic compound catabolic processGO:00194391680.020
regulation of cell morphogenesisGO:0022604770.020
multicellular organismal reproductive processGO:00486092330.020
cellular macromolecule localizationGO:00707271220.020
regulation of locomotionGO:00400121480.020
developmental growthGO:00485891000.020
nucleoside triphosphate metabolic processGO:00091411440.020
cytoskeleton organizationGO:00070101110.020
response to transition metal nanoparticleGO:19902671220.020
regulation of response to woundingGO:1903034690.020
regulation of system processGO:00440572080.020
regulation of secretionGO:00510462240.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
positive regulation of phosphate metabolic processGO:00459372620.019
positive regulation of cell motilityGO:2000147970.019
purine nucleoside triphosphate metabolic processGO:00091441410.019
purine ribonucleoside metabolic processGO:00461281680.019
anion transportGO:00068201780.019
cell morphogenesisGO:00009021420.019
purine nucleotide metabolic processGO:00061632290.019
agingGO:00075682410.019
secretionGO:00469033070.019
response to campGO:0051591910.019
response to external biotic stimulusGO:00432072210.019
proteolysisGO:00065081750.019
regulation of neuron projection developmentGO:00109751610.019
positive regulation of apoptotic processGO:00430651540.019
peptidyl tyrosine phosphorylationGO:0018108720.018
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
regulation of rna biosynthetic processGO:20011413810.018
inorganic cation transmembrane transportGO:00986622020.018
catabolic processGO:00090563510.018
cellular response to hormone stimulusGO:00328702470.018
regulation of immune system processGO:00026821230.018
regulation of cell adhesionGO:0030155520.018
Human Rat
neurological system processGO:00508772190.018
Rat
negative regulation of cellular metabolic processGO:00313242810.018
cellular calcium ion homeostasisGO:00068741600.018
organic acid biosynthetic processGO:0016053830.018
small molecule biosynthetic processGO:00442831240.018
negative regulation of nervous system developmentGO:0051961790.018
monocarboxylic acid metabolic processGO:00327871520.018
positive regulation of nucleoside metabolic processGO:0045979550.018
central nervous system developmentGO:00074173110.018
nucleotide catabolic processGO:00091661390.018
regulation of response to stressGO:00801341260.018
response to reactive oxygen speciesGO:00003021200.018
smooth muscle cell proliferationGO:0048659770.017
response to biotic stimulusGO:00096072260.017
carbohydrate derivative metabolic processGO:19011353460.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
organic cyclic compound catabolic processGO:19013611750.017
purine ribonucleotide metabolic processGO:00091502270.017
organ formationGO:004864530.017
divalent inorganic cation transportGO:00725111340.017
cation transmembrane transportGO:00986552630.017
cell motilityGO:00488702020.017
hepaticobiliary system developmentGO:0061008900.017
regulation of map kinase activityGO:0043405530.017
regulation of protein phosphorylationGO:00019321830.017
purine ribonucleoside catabolic processGO:00461301240.017
regulation of phosphorylationGO:00423252480.017
fatty acid metabolic processGO:0006631990.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
cognitionGO:0050890920.016
head developmentGO:00603222470.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
calcium ion homeostasisGO:00550741620.016
positive regulation of intracellular signal transductionGO:19025331380.016
positive regulation of gene expressionGO:00106282440.016
blood circulationGO:00080151830.016
mesoderm developmentGO:000749820.016
response to glucoseGO:00097491360.016
negative regulation of cellular component organizationGO:0051129830.016
negative regulation of rna metabolic processGO:00512531230.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
tissue regenerationGO:0042246360.016
ribose phosphate metabolic processGO:00196932350.016
cellular response to external stimulusGO:00714961180.015
locomotionGO:00400112370.015
negative regulation of response to stimulusGO:00485851550.015
cell growthGO:00160491040.015
Human
heterocycle catabolic processGO:00467001670.015
cell morphogenesis involved in differentiationGO:00009041190.015
single organism cellular localizationGO:19025801020.015
response to temperature stimulusGO:0009266940.015
negative regulation of gene expressionGO:00106291990.015
hormone transportGO:00099141210.015
glycosyl compound catabolic processGO:19016581260.015
regulation of secretion by cellGO:19035302080.015
biological adhesionGO:00226101100.015
Human Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
neuron projection morphogenesisGO:00488121220.015
response to hydrogen peroxideGO:0042542890.015
negative regulation of signalingGO:00230571570.015
regulation of neuron deathGO:19012141150.015
response to ethanolGO:00454711620.015
learning or memoryGO:0007611900.015
regulation of blood circulationGO:19035221100.015
regulation of hormone levelsGO:00108171870.015
response to toxic substanceGO:00096361330.015
sodium ion transportGO:0006814820.015
positive regulation of rna biosynthetic processGO:19026801970.014
cellular response to organic cyclic compoundGO:00714072020.014
camera type eye developmentGO:0043010480.014
response to nutrientGO:00075842480.014
Rat
angiogenesisGO:0001525530.014
Human
epithelial cell proliferationGO:0050673540.014
regulation of blood vessel sizeGO:0050880890.014
cellular response to nitrogen compoundGO:19016992100.014
cell projection organizationGO:00300303020.014
regulation of response to external stimulusGO:00321011060.014
negative regulation of neurogenesisGO:0050768780.014
reactive nitrogen species metabolic processGO:200105710.014
response to other organismGO:00517072200.014
regulation of angiogenesisGO:0045765390.014
Human
response to ketoneGO:19016541820.014
positive regulation of catabolic processGO:0009896780.014
cellular cation homeostasisGO:00300031800.014
immunoglobulin mediated immune responseGO:001606440.014
cell substrate adhesionGO:0031589290.014
anterior posterior pattern specificationGO:000995210.014
regulation of cellular catabolic processGO:00313291010.014
protein autophosphorylationGO:0046777660.014
axis specificationGO:000979840.014
negative regulation of cell differentiationGO:0045596990.014
cardiovascular system developmentGO:00723581340.013
Human
peptide hormone secretionGO:0030072840.013
positive regulation of nervous system developmentGO:00519621780.013
positive regulation of phosphorylationGO:00423271770.013
neuron developmentGO:00486662860.013
response to alkaloidGO:00432791320.013
regulation of cellular component biogenesisGO:0044087860.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
divalent inorganic cation homeostasisGO:00725071650.013
action potentialGO:0001508540.013
eye developmentGO:0001654500.013
negative regulation of molecular functionGO:00440921330.013
cell part morphogenesisGO:00329901230.013
positive regulation of neurogenesisGO:00507691650.013
regulation of purine nucleotide catabolic processGO:0033121650.013
purine nucleoside catabolic processGO:00061521240.013
positive regulation of cell migrationGO:0030335960.013
negative regulation of catalytic activityGO:00430861030.013
regulation of homotypic cell cell adhesionGO:003411040.013
positive regulation of nucleotide catabolic processGO:0030813530.013
cellular response to reactive oxygen speciesGO:0034614550.013
ribonucleoside catabolic processGO:00424541260.013
cellular protein localizationGO:00346131220.013
peptide transportGO:0015833970.013
calcium ion transportGO:00068161310.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
Human
purine containing compound metabolic processGO:00725212530.012
sexual reproductionGO:00199531480.012
positive regulation of cell projection organizationGO:00313461110.012
single organism membrane organizationGO:0044802740.012
response to vitaminGO:00332731310.012
regulation of synaptic transmissionGO:00508041410.012
synaptic transmissionGO:00072682350.012
cellular response to oxidative stressGO:0034599760.012
ribonucleoside triphosphate catabolic processGO:00092031220.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
reproductionGO:00000032450.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
nucleoside triphosphate catabolic processGO:00091431230.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
response to activityGO:0014823730.012
actin cytoskeleton organizationGO:0030036730.012
cardiac conductionGO:006133720.012
lipid biosynthetic processGO:00086101280.012
cellular response to inorganic substanceGO:0071241650.012
myelinationGO:0042552390.012
response to insulinGO:00328681330.012
regulation of growthGO:00400081050.012
Human
peptide secretionGO:0002790860.012
regulation of anatomical structure sizeGO:00900661350.012
ribonucleotide metabolic processGO:00092592310.012
formation of primary germ layerGO:000170410.011
cellular response to steroid hormone stimulusGO:0071383930.011
nucleoside catabolic processGO:00091641260.011
muscle organ developmentGO:0007517500.011
positive regulation of transportGO:00510502450.011
memoryGO:0007613540.011
regenerationGO:00310991630.011
multi multicellular organism processGO:00447061380.011
regulation of epithelial cell proliferationGO:0050678490.011
spermatogenesisGO:0007283990.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
gastrulationGO:000736920.011
regulation of canonical wnt signaling pathwayGO:006082840.011
rho protein signal transductionGO:0007266110.011
cytosolic calcium ion homeostasisGO:00514801400.011
negative regulation of cell developmentGO:0010721820.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
regulation of nucleoside metabolic processGO:0009118660.011
transmission of nerve impulseGO:0019226420.011
blood vessel developmentGO:0001568690.011
Human
negative regulation of transportGO:00510511360.011
synaptic growth at neuromuscular junctionGO:005112410.011
regulation of purine nucleotide metabolic processGO:19005421150.011
positive regulation of transcription dna templatedGO:00458931970.011
regulation of nucleotide catabolic processGO:0030811650.011
positive regulation of signal transductionGO:00099671750.011
reactive oxygen species biosynthetic processGO:190340980.011
organ morphogenesisGO:0009887750.011
eye morphogenesisGO:004859240.011
response to electrical stimulusGO:0051602560.011
cellular response to lipidGO:00713962010.011
platelet aggregationGO:007052740.011
lymphocyte activation involved in immune responseGO:000228530.011
positive regulation of hydrolase activityGO:0051345860.011
establishment of protein localizationGO:00451841410.010
male gamete generationGO:0048232990.010
regulation of defense responseGO:0031347680.010
cellular lipid metabolic processGO:00442552080.010
carbohydrate metabolic processGO:00059751300.010
developmental process involved in reproductionGO:00030061590.010
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
extracellular matrix constituent secretionGO:007027840.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
regulation of transferase activityGO:00513381230.010
neuron fate commitmentGO:004866340.010
immune responseGO:00069551040.010
ameboidal type cell migrationGO:0001667260.010
negative regulation of response to external stimulusGO:0032102370.010
cellular response to metal ionGO:0071248550.010
regulation of smooth muscle cell proliferationGO:0048660750.010
guanosine containing compound catabolic processGO:1901069710.010
gliogenesisGO:0042063930.010
negative regulation of neuron deathGO:1901215690.010
response to corticosteroidGO:00319602350.010
positive regulation of neuron differentiationGO:00456661260.010
appendage morphogenesisGO:003510740.010
positive regulation of immune system processGO:0002684900.010

Alox12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
urinary system diseaseDOID:1800.037
kidney diseaseDOID:55700.026
nervous system diseaseDOID:86300.016
central nervous system diseaseDOID:33100.013
musculoskeletal system diseaseDOID:1700.011