Rattus norvegicus

29 known processes

Chek2

CHK2 checkpoint homolog (S. pombe)

(Aliases: Rad53,Chk2)

Chek2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled receptor signaling pathwayGO:00071862420.133
regulation of phosphorus metabolic processGO:00511743490.095
cellular amino acid metabolic processGO:00065201070.088
regulation of molecular functionGO:00650093980.075
single organism intracellular transportGO:19025821660.070
single organism catabolic processGO:00447122830.059
nucleoside phosphate metabolic processGO:00067532830.056
immune system processGO:00023762040.055
response to extracellular stimulusGO:00099913800.054
regulation of kinase activityGO:00435491170.051
reproductive processGO:00224143720.047
multi organism reproductive processGO:00447032620.046
apoptotic processGO:00069153810.046
positive regulation of cellular protein metabolic processGO:00322701670.045
programmed cell deathGO:00125013920.045
positive regulation of multicellular organismal processGO:00512403870.045
carboxylic acid metabolic processGO:00197522890.044
macromolecule localizationGO:00330362520.044
regulation of catalytic activityGO:00507903040.043
organelle organizationGO:00069962660.043
positive regulation of cell deathGO:00109421840.042
response to nutrient levelsGO:00316673700.042
establishment of protein localizationGO:00451841410.042
regulation of protein metabolic processGO:00512462890.041
response to molecule of bacterial originGO:00022371940.040
intracellular signal transductionGO:00355563140.039
positive regulation of phosphorus metabolic processGO:00105622620.039
positive regulation of catalytic activityGO:00430851840.038
regulation of programmed cell deathGO:00430673410.038
regulation of cellular amine metabolic processGO:003323880.038
catabolic processGO:00090563510.037
amine metabolic processGO:0009308380.036
positive regulation of phosphorylationGO:00423271770.036
positive regulation of phosphate metabolic processGO:00459372620.035
regulation of cellular amino acid metabolic processGO:000652120.034
negative regulation of neutrophil apoptotic processGO:003303030.034
response to other organismGO:00517072200.033
cellular catabolic processGO:00442482950.033
oxoacid metabolic processGO:00434362900.032
purine nucleoside metabolic processGO:00422781690.032
positive regulation of cell communicationGO:00106472710.032
regulation of cellular component organizationGO:00511283680.032
purine ribonucleoside metabolic processGO:00461281680.032
positive regulation of response to stimulusGO:00485842850.031
regulation of cellular protein metabolic processGO:00322682670.031
agingGO:00075682410.029
cellular ketone metabolic processGO:0042180510.029
organic substance catabolic processGO:19015753160.028
nucleobase containing small molecule metabolic processGO:00550863160.028
single organism biosynthetic processGO:00447113420.028
cellular amine metabolic processGO:0044106380.027
cellular modified amino acid metabolic processGO:0006575610.027
regulation of secretion by cellGO:19035302080.027
nucleoside metabolic processGO:00091161790.026
cellular homeostasisGO:00197252520.026
positive regulation of transportGO:00510502450.025
positive regulation of cellular biosynthetic processGO:00313282950.025
lipid metabolic processGO:00066292830.025
nucleotide metabolic processGO:00091172790.025
protein localizationGO:00081041910.025
regulation of protein phosphorylationGO:00019321830.024
positive regulation of cellular component organizationGO:00511302000.024
positive regulation of programmed cell deathGO:00430681570.024
regulation of cell proliferationGO:00421273590.023
organophosphate metabolic processGO:00196373700.023
negative regulation of metabolic processGO:00098923310.023
chemical homeostasisGO:00488782920.023
organic acid metabolic processGO:00060822920.023
response to external biotic stimulusGO:00432072210.023
response to oxygen levelsGO:00704822650.023
organophosphate catabolic processGO:00464341480.023
glycosyl compound metabolic processGO:19016571820.023
response to decreased oxygen levelsGO:00362932370.022
dephosphorylationGO:0016311980.022
response to lipopolysaccharideGO:00324961910.022
negative regulation of natural killer cell mediated immunityGO:000271640.021
negative regulation of cellular metabolic processGO:00313242810.021
ribonucleoside metabolic processGO:00091191740.021
purine ribonucleotide catabolic processGO:00091541360.021
ribose phosphate metabolic processGO:00196932350.021
inflammatory responseGO:00069541500.020
positive regulation of cell proliferationGO:00082842490.020
intracellular transportGO:00469071850.020
immune effector processGO:0002252530.020
nucleoside triphosphate catabolic processGO:00091431230.019
reactive oxygen species metabolic processGO:0072593370.019
regulation of hydrolase activityGO:00513361430.019
regulation of apoptotic processGO:00429813350.019
ribonucleotide metabolic processGO:00092592310.019
response to growth factorGO:00708481890.019
immune responseGO:00069551040.019
positive regulation of cellular amine metabolic processGO:003324030.019
cellular response to growth factor stimulusGO:00713631620.018
regulation of protein modification processGO:00313991940.018
regulation of mesenchymal cell proliferationGO:001046440.018
positive regulation of protein metabolic processGO:00512471780.018
negative regulation of cell differentiationGO:0045596990.018
metal ion homeostasisGO:00550651860.018
regulation of protein kinase activityGO:00458591050.018
regulation of cell migrationGO:00303341280.018
glycerolipid metabolic processGO:0046486670.018
cation transportGO:00068123820.018
negative regulation of nervous system developmentGO:0051961790.018
positive regulation of signal transductionGO:00099671750.018
sexual reproductionGO:00199531480.018
cellular response to endogenous stimulusGO:00714953770.018
protein phosphorylationGO:00064683450.018
nucleobase containing compound catabolic processGO:00346551520.018
purine containing compound metabolic processGO:00725212530.017
regulation of transferase activityGO:00513381230.017
negative regulation of protein metabolic processGO:00512481140.017
organophosphate biosynthetic processGO:00904071430.017
positive regulation of the force of heart contraction by norepinephrineGO:000306110.017
positive regulation of nitrogen compound metabolic processGO:00511733340.017
heterocycle catabolic processGO:00467001670.017
macromolecular complex assemblyGO:00650032730.017
organic cyclic compound catabolic processGO:19013611750.017
regulation of reactive oxygen species metabolic processGO:2000377260.017
response to peptide hormoneGO:00434342780.017
response to bacteriumGO:00096172000.017
glycosyl compound catabolic processGO:19016581260.017
regulation of cellular ketone metabolic processGO:0010565270.017
cellular chemical homeostasisGO:00550822470.016
positive regulation of immune system processGO:0002684900.016
response to nutrientGO:00075842480.016
small gtpase mediated signal transductionGO:0007264360.016
cell adhesionGO:00071551100.016
regulation of multicellular organismal developmentGO:20000263760.016
negative regulation of molecular functionGO:00440921330.016
positive regulation of organelle organizationGO:0010638480.016
guanosine containing compound metabolic processGO:1901068740.016
regulation of phosphorylationGO:00423252480.016
angiogenesisGO:0001525530.016
positive regulation of biosynthetic processGO:00098913190.016
single organism organelle organizationGO:19025891800.016
negative regulation of programmed cell deathGO:00430691830.016
regulation of cytokine productionGO:0001817560.016
t cell tolerance inductionGO:000251730.016
negative regulation of cellular protein metabolic processGO:00322691060.016
small molecule catabolic processGO:0044282590.015
biological adhesionGO:00226101100.015
nucleoside phosphate catabolic processGO:19012921400.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
regulation of intracellular signal transductionGO:19025312180.015
proteolysisGO:00065081750.015
response to biotic stimulusGO:00096072260.015
regulation of vesicle mediated transportGO:0060627810.015
vesicle mediated transportGO:00161921810.015
multicellular organism reproductionGO:00325042330.015
synaptic transmissionGO:00072682350.015
regulation of cellular localizationGO:00603412630.015
response to hypoxiaGO:00016662310.015
macromolecular complex subunit organizationGO:00439333390.015
regulation of cell differentiationGO:00455953200.015
regulation of immune system processGO:00026821230.015
negative regulation of macromolecule metabolic processGO:00106052600.015
cell migrationGO:00164771970.014
regulation of response to stressGO:00801341260.014
regulation of cellular catabolic processGO:00313291010.014
cytokine productionGO:0001816610.014
negative regulation of cell developmentGO:0010721820.014
regulation of phosphate metabolic processGO:00192203490.014
positive regulation of cellular component biogenesisGO:0044089550.014
multicellular organism growthGO:003526410.014
negative regulation of multicellular organismal processGO:00512412030.014
female pregnancyGO:00075651220.014
positive regulation of tolerance inductionGO:000264510.014
peptidyl amino acid modificationGO:00181931260.014
gtp catabolic processGO:0006184710.014
positive regulation of protein phosphorylationGO:00019341350.014
single organism reproductive processGO:00447022970.014
phospholipid metabolic processGO:0006644610.014
cardiovascular system developmentGO:00723581340.014
negative regulation of catalytic activityGO:00430861030.013
regulation of immune responseGO:0050776550.013
reproductionGO:00000032450.013
positive regulation of secretionGO:00510471400.013
cellular lipid metabolic processGO:00442552080.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
cellular component assemblyGO:00226073600.013
response to ethanolGO:00454711620.013
positive regulation of molecular functionGO:00440932300.013
positive regulation of developmental processGO:00510942830.013
carbohydrate derivative metabolic processGO:19011353460.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
organ regenerationGO:00311001010.013
regenerationGO:00310991630.013
purine containing compound catabolic processGO:00725231380.013
gamete generationGO:00072761240.013
positive regulation of mapk cascadeGO:0043410920.013
calcium ion homeostasisGO:00550741620.012
cellular response to oxygen containing compoundGO:19017013860.012
cellular macromolecule localizationGO:00707271220.012
purine ribonucleotide metabolic processGO:00091502270.012
guanosine containing compound catabolic processGO:1901069710.012
response to cytokineGO:00340972150.012
cellular nitrogen compound catabolic processGO:00442701630.012
negative regulation of cellular component organizationGO:0051129830.012
cytoplasmic transportGO:00164821150.012
jak stat cascadeGO:0007259260.012
regulation of synaptic transmissionGO:00508041410.012
cation homeostasisGO:00550801950.012
positive regulation of protein modification processGO:00314011420.012
homeostatic processGO:00425923310.012
reactive oxygen species biosynthetic processGO:190340980.012
organic acid catabolic processGO:0016054490.012
cell cycle processGO:0022402570.012
cellular component biogenesisGO:00440853680.012
calcium ion transportGO:00068161310.012
regulation of catabolic processGO:00098941130.012
positive regulation of apoptotic processGO:00430651540.012
rhythmic processGO:00485111560.012
cell cycleGO:00070491010.012
multicellular organismal reproductive processGO:00486092330.011
negative regulation of developmental processGO:00510931250.011
positive regulation of protein kinase activityGO:0045860730.011
regulation of homeostatic processGO:00328441010.011
organ formationGO:004864530.011
cellular response to external stimulusGO:00714961180.011
protein complex assemblyGO:00064612630.011
nucleotide biosynthetic processGO:0009165980.011
regulation of intracellular transportGO:0032386650.011
sex differentiationGO:00075481130.011
calcium mediated signalingGO:0019722230.011
response to peptideGO:19016522920.011
acute inflammatory responseGO:0002526580.011
hepaticobiliary system developmentGO:0061008900.011
negative regulation of homeostatic processGO:0032845470.011
divalent inorganic cation transportGO:00725111340.011
protein transportGO:00150311320.011
aromatic compound catabolic processGO:00194391680.011
regulation of signal transductionGO:00099663180.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
multi multicellular organism processGO:00447061380.011
response to estrogenGO:00436272320.011
mapk cascadeGO:00001651400.011
ion transmembrane transportGO:00342203650.011
carboxylic acid catabolic processGO:0046395490.011
embryonic skeletal system developmentGO:004870630.011
nucleoside catabolic processGO:00091641260.011
dna metabolic processGO:0006259960.011
positive regulation of immune responseGO:0050778420.011
embryonic pattern specificationGO:000988010.011
angioblast cell migrationGO:003547610.011
positive regulation of cell developmentGO:00107201760.010
adaptive immune responseGO:0002250140.010
secretionGO:00469033070.010
response to woundingGO:00096112540.010
reactive nitrogen species metabolic processGO:200105710.010
metanephric tubule developmentGO:007217040.010
defense responseGO:00069521940.010
purine nucleotide metabolic processGO:00061632290.010
regulation of defense responseGO:0031347680.010
positive regulation of cell projection organizationGO:00313461110.010
response to transforming growth factor betaGO:0071559460.010
negative regulation of apoptotic processGO:00430661810.010
positive regulation of nucleobase containing compound metabolic processGO:00459353190.010
purine ribonucleoside catabolic processGO:00461301240.010
nucleotide catabolic processGO:00091661390.010
negative regulation of neurogenesisGO:0050768780.010
negative regulation of cell proliferationGO:00082851190.010
cellular protein localizationGO:00346131220.010

Chek2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.017
central nervous system diseaseDOID:33100.017
disease of anatomical entityDOID:700.017
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.010
organ system cancerDOID:005068600.010
cardiovascular system diseaseDOID:128700.010
disease of metabolismDOID:001466700.010