Rattus norvegicus

113 known processes

Chek1

CHK1 checkpoint homolog (S. pombe)

Chek1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to stressGO:00335542690.084
cell cycleGO:00070491010.049
cell projection organizationGO:00300303020.048
double strand break repairGO:000630210.045
Human
macromolecular complex subunit organizationGO:00439333390.043
Human Mouse
regulation of protein metabolic processGO:00512462890.043
Mouse
tetrahydrofolate metabolic processGO:004665390.042
nucleic acid templated transcriptionGO:00976593790.042
Mouse
response to oxygen levelsGO:00704822650.041
cellular component biogenesisGO:00440853680.041
programmed cell deathGO:00125013920.039
Zebrafish
negative regulation of metabolic processGO:00098923310.039
macromolecule localizationGO:00330362520.038
cellular response to oxygen containing compoundGO:19017013860.036
single organism biosynthetic processGO:00447113420.036
apoptotic processGO:00069153810.036
Zebrafish
single organism reproductive processGO:00447022970.035
anatomical structure morphogenesisGO:00096532980.034
cellular component assemblyGO:00226073600.034
multicellular organismal reproductive processGO:00486092330.033
multi organism reproductive processGO:00447032620.033
rna metabolic processGO:00160704060.032
Mouse
cell cycle checkpointGO:000007520.032
Human Zebrafish Mouse
protein phosphorylationGO:00064683450.031
oxoacid metabolic processGO:00434362900.030
chromosome segregationGO:000705920.030
cell cycle processGO:0022402570.030
response to inorganic substanceGO:00100353770.030
negative regulation of macromolecule metabolic processGO:00106052600.030
neuron differentiationGO:00301823680.030
intracellular signal transductionGO:00355563140.030
Zebrafish
cellular amino acid metabolic processGO:00065201070.029
multicellular organism reproductionGO:00325042330.029
rna biosynthetic processGO:00327743800.029
Mouse
regulation of cellular component organizationGO:00511283680.029
Human Mouse
protein complex subunit organizationGO:00718223020.029
organelle organizationGO:00069962660.028
Human Mouse
response to decreased oxygen levelsGO:00362932370.028
response to metal ionGO:00100382530.028
rhythmic processGO:00485111560.028
regulation of transcription dna templatedGO:00063553740.027
Mouse
reproductive processGO:00224143720.027
regulation of programmed cell deathGO:00430673410.026
response to hypoxiaGO:00016662310.026
transcription from rna polymerase ii promoterGO:00063662520.026
Mouse
negative regulation of gene expressionGO:00106291990.025
reproductionGO:00000032450.025
regulation of rna metabolic processGO:00512523910.025
Mouse
response to estradiolGO:00323551640.025
head developmentGO:00603222470.025
regulation of cellular protein metabolic processGO:00322682670.024
Mouse
developmental process involved in reproductionGO:00030061590.024
negative regulation of cellular metabolic processGO:00313242810.024
macromolecular complex assemblyGO:00650032730.024
tissue developmentGO:00098882520.023
regulation of rna biosynthetic processGO:20011413810.023
Mouse
secretionGO:00469033070.023
central nervous system developmentGO:00074173110.023
locomotionGO:00400112370.023
regulation of cell cycleGO:0051726730.023
cellular amine metabolic processGO:0044106380.023
positive regulation of cell proliferationGO:00082842490.022
homeostatic processGO:00425923310.022
regulation of phosphorylationGO:00423252480.022
regulation of nucleic acid templated transcriptionGO:19035063800.022
Mouse
agingGO:00075682410.022
neuron developmentGO:00486662860.021
regulation of phosphorus metabolic processGO:00511743490.021
response to peptide hormoneGO:00434342780.021
positive regulation of nitrogen compound metabolic processGO:00511733340.021
Mouse
response to estrogenGO:00436272320.020
dna integrity checkpointGO:003157020.020
Human Zebrafish Mouse
peptidyl amino acid modificationGO:00181931260.020
Human Mouse
regulation of cellular amino acid metabolic processGO:000652120.020
regulation of cell proliferationGO:00421273590.020
Mouse
folic acid containing compound metabolic processGO:0006760100.020
amine metabolic processGO:0009308380.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
Mouse
positive regulation of cellular biosynthetic processGO:00313282950.020
Mouse
protein complex biogenesisGO:00702712630.019
response to transition metal nanoparticleGO:19902671220.019
carboxylic acid metabolic processGO:00197522890.019
regulation of molecular functionGO:00650093980.019
regulation of mrna splicing via spliceosomeGO:004802430.019
positive regulation of response to stimulusGO:00485842850.019
regulation of cell differentiationGO:00455953200.019
positive regulation of protein metabolic processGO:00512471780.018
response to corticosteroidGO:00319602350.018
proteolysisGO:00065081750.018
regulation of apoptotic processGO:00429813350.018
cellular catabolic processGO:00442482950.018
centrosome organizationGO:005129710.018
Human
cellular response to organonitrogen compoundGO:00714171970.018
regulation of cellular amine metabolic processGO:003323880.018
negative regulation of protein metabolic processGO:00512481140.018
brain developmentGO:00074202470.017
reproductive system developmentGO:00614581280.017
transcription dna templatedGO:00063513770.017
Mouse
negative regulation of apoptotic processGO:00430661810.017
positive regulation of gene expressionGO:00106282440.017
Mouse
organic substance catabolic processGO:19015753160.017
negative regulation of mitotic cell cycle phase transitionGO:190199130.017
single organism organelle organizationGO:19025891800.017
Human Mouse
regulation of cellular ketone metabolic processGO:0010565270.017
cellular component movementGO:00069282480.016
cellular response to endogenous stimulusGO:00714953770.016
chemical homeostasisGO:00488782920.016
response to nutrient levelsGO:00316673700.016
positive regulation of multicellular organismal processGO:00512403870.016
response to carbohydrateGO:00097431830.016
metaphase anaphase transition of cell cycleGO:004478410.016
negative regulation of programmed cell deathGO:00430691830.016
response to growth factorGO:00708481890.016
regulation of multicellular organismal developmentGO:20000263760.016
response to ketoneGO:19016541820.016
centrosome cycleGO:000709810.016
Human
negative regulation of nitrogen compound metabolic processGO:00511721610.015
protein complex assemblyGO:00064612630.015
negative regulation of cell deathGO:00605482290.015
positive regulation of rna metabolic processGO:00512542030.015
Mouse
regulation of phosphate metabolic processGO:00192203490.015
cell cell signalingGO:00072673350.015
response to radiationGO:00093141370.015
Mouse
response to acid chemicalGO:00011012220.015
pteridine containing compound metabolic processGO:0042558140.015
organic acid metabolic processGO:00060822920.015
negative regulation of cellular protein metabolic processGO:00322691060.015
regulation of nervous system developmentGO:00519602640.015
development of primary sexual characteristicsGO:00451371070.015
cellular ketone metabolic processGO:0042180510.015
alpha amino acid biosynthetic processGO:1901607230.015
dna metabolic processGO:0006259960.015
catabolic processGO:00090563510.015
positive regulation of phosphate metabolic processGO:00459372620.015
response to peptideGO:19016522920.015
reproductive structure developmentGO:00486081280.015
alpha amino acid metabolic processGO:1901605710.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
Mouse
regulation of catalytic activityGO:00507903040.014
regulation of neurogenesisGO:00507672470.014
nucleobase containing small molecule metabolic processGO:00550863160.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
regulation of protein phosphorylationGO:00019321830.014
neuron projection developmentGO:00311752730.014
sex differentiationGO:00075481130.014
regulation of cell developmentGO:00602842630.014
rna localizationGO:000640340.014
protein localizationGO:00081041910.014
mitotic sister chromatid separationGO:005130610.014
nucleoside phosphate metabolic processGO:00067532830.014
response to extracellular stimulusGO:00099913800.014
regulation of proteasomal protein catabolic processGO:006113640.014
regulation of anatomical structure morphogenesisGO:00226031410.014
cellular response to organic cyclic compoundGO:00714072020.014
response to alkaloidGO:00432791320.014
axis specificationGO:000979840.013
nitrogen compound transportGO:00717052290.013
eye morphogenesisGO:004859240.013
regulation of cellular localizationGO:00603412630.013
response to glucocorticoidGO:00513842230.013
positive regulation of apoptotic processGO:00430651540.013
cellular response to growth factor stimulusGO:00713631620.013
cellular response to lipidGO:00713962010.013
secretion by cellGO:00329402480.013
positive regulation of developmental processGO:00510942830.013
negative regulation of phosphorus metabolic processGO:0010563800.013
response to nutrientGO:00075842480.013
positive regulation of programmed cell deathGO:00430681570.013
positive regulation of cellular protein metabolic processGO:00322701670.013
regulation of signal transductionGO:00099663180.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
gonad developmentGO:00084061040.013
defense responseGO:00069521940.013
protein oligomerizationGO:00512591910.012
cellular chemical homeostasisGO:00550822470.012
negative regulation of biosynthetic processGO:00098901680.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
negative regulation of cell communicationGO:00106481580.012
cellular modified amino acid biosynthetic processGO:0042398180.012
response to purine containing compoundGO:00140741260.012
positive regulation of rna biosynthetic processGO:19026801970.012
Mouse
regulation of sister chromatid segregationGO:003304510.012
sexual reproductionGO:00199531480.012
cytoplasmic transportGO:00164821150.012
positive regulation of molecular functionGO:00440932300.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
gamete generationGO:00072761240.012
maintenance of locationGO:0051235170.012
microtubule organizing center organizationGO:003102310.012
Human
positive regulation of cellular amine metabolic processGO:003324030.012
regulation of response to stressGO:00801341260.012
Human
response to lipopolysaccharideGO:00324961910.012
positive regulation of phosphorus metabolic processGO:00105622620.012
spermatogenesisGO:0007283990.012
metaphase anaphase transition of mitotic cell cycleGO:000709110.012
cellular cation homeostasisGO:00300031800.012
purine containing compound metabolic processGO:00725212530.012
response to oxidative stressGO:00069791860.012
response to molecule of bacterial originGO:00022371940.011
intracellular transportGO:00469071850.011
response to toxic substanceGO:00096361330.011
nucleotide metabolic processGO:00091172790.011
cellular homeostasisGO:00197252520.011
cellular nitrogen compound catabolic processGO:00442701630.011
ovulation cycleGO:0042698670.011
transmembrane transportGO:00550854120.011
response to ethanolGO:00454711620.011
regulation of organelle organizationGO:0033043800.011
Human Mouse
regulation of cell projection organizationGO:00313441750.011
dna recombinationGO:000631030.011
Human
purine ribonucleotide metabolic processGO:00091502270.011
embryo developmentGO:0009790490.011
positive regulation of phosphorylationGO:00423271770.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
Mouse
mitotic cell cycle checkpointGO:000709310.011
Zebrafish
positive regulation of cellular component organizationGO:00511302000.011
chromatin modificationGO:0016568330.011
Human Mouse
positive regulation of cell differentiationGO:00455972170.011
mitotic cell cycle phase transitionGO:0044772200.011
negative regulation of signalingGO:00230571570.011
negative regulation of cellular component organizationGO:0051129830.011
Human
positive regulation of transcription dna templatedGO:00458931970.011
Mouse
cofactor metabolic processGO:0051186950.010
sister chromatid segregationGO:000081910.010
positive regulation of nucleobase containing compound metabolic processGO:00459353190.010
Mouse
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
tube developmentGO:0035295890.010
behaviorGO:00076102050.010
positive regulation of biosynthetic processGO:00098913190.010
Mouse
synaptic transmissionGO:00072682350.010
regulation of protein modification processGO:00313991940.010
Mouse
male gamete generationGO:0048232990.010
ion homeostasisGO:00508012120.010
anterior posterior pattern specificationGO:000995210.010

Chek1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012
organ system cancerDOID:005068600.011