Rattus norvegicus

23 known processes

Slco1a1

solute carrier organic anion transporter family, member 1a1

(Aliases: OATP-1,Slc21a3,Oatp1,Slc21a1)

Slco1a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to corticosteroidGO:00319602350.574
response to nutrient levelsGO:00316673700.562
response to bacteriumGO:00096172000.488
hormone transportGO:00099141210.486
biphenyl catabolic processGO:007098020.479
oligopeptide transportGO:000685740.403
cellular response to hormone stimulusGO:00328702470.375
response to peptideGO:19016522920.359
cellular response to corticosteroid stimulusGO:0071384690.350
cellular response to organic cyclic compoundGO:00714072020.348
cellular response to lipidGO:00713962010.312
response to glucocorticoidGO:00513842230.271
response to peptide hormoneGO:00434342780.243
positive regulation of secretionGO:00510471400.230
lauric acid metabolic processGO:004825240.221
regulation of hormone levelsGO:00108171870.203
cellular response to steroid hormone stimulusGO:0071383930.201
lipid metabolic processGO:00066292830.197
cellular response to glucocorticoid stimulusGO:0071385680.183
regulation of secretionGO:00510462240.179
immune system processGO:00023762040.168
response to metal ionGO:00100382530.168
nitrogen compound transportGO:00717052290.164
organic acid metabolic processGO:00060822920.164
response to ethanolGO:00454711620.155
blood circulationGO:00080151830.154
multi organism reproductive processGO:00447032620.153
response to ddtGO:004668010.150
modified amino acid transportGO:0072337120.150
response to alkaloidGO:00432791320.146
androgen biosynthetic processGO:0006702100.146
response to toxic substanceGO:00096361330.142
small molecule biosynthetic processGO:00442831240.141
insecticide metabolic processGO:001714340.138
alkaloid metabolic processGO:000982030.137
response to other organismGO:00517072200.128
multi multicellular organism processGO:00447061380.125
calcitriol biosynthetic process from calciolGO:003637820.123
response to ketoneGO:19016541820.122
learning or memoryGO:0007611900.122
halogenated hydrocarbon metabolic processGO:004219740.121
behaviorGO:00076102050.117
response to acid chemicalGO:00011012220.115
chlorinated hydrocarbon metabolic processGO:004219640.113
steroid metabolic processGO:0008202730.108
response to inorganic substanceGO:00100353770.108
response to reactive oxygen speciesGO:00003021200.105
aromatic amino acid family catabolic processGO:000907470.105
organic hydroxy compound biosynthetic processGO:1901617510.105
response to oxidative stressGO:00069791860.103
regulation of programmed cell deathGO:00430673410.102
linoleic acid metabolic processGO:004365140.101
response to extracellular stimulusGO:00099913800.100
exogenous drug catabolic processGO:004273810.099
response to external biotic stimulusGO:00432072210.091
isoprenoid metabolic processGO:0006720450.091
organic hydroxy compound metabolic processGO:19016151150.090
steroid biosynthetic processGO:0006694480.089
benzene containing compound metabolic processGO:0042537220.086
positive regulation of multicellular organismal processGO:00512403870.085
oxoacid metabolic processGO:00434362900.084
response to growth factorGO:00708481890.083
immune responseGO:00069551040.083
intracellular signal transductionGO:00355563140.082
regulation of phosphorus metabolic processGO:00511743490.082
carboxylic acid metabolic processGO:00197522890.081
response to nutrientGO:00075842480.080
drug transmembrane transportGO:0006855130.079
gland developmentGO:00487321550.079
cellular response to oxygen containing compoundGO:19017013860.078
circulatory system processGO:00030131830.077
amine transportGO:0015837570.077
indolalkylamine metabolic processGO:000658650.077
response to xenobiotic stimulusGO:0009410230.076
phenol containing compound metabolic processGO:0018958300.076
cellular response to endogenous stimulusGO:00714953770.076
amide transportGO:00428861050.075
toxin catabolic processGO:000940710.075
organic anion transportGO:00157111320.073
terpenoid metabolic processGO:0006721370.073
icosanoid metabolic processGO:0006690380.072
positive regulation of programmed cell deathGO:00430681570.071
positive regulation of secretion by cellGO:19035321280.069
cellular amino acid metabolic processGO:00065201070.069
aromatic amino acid family metabolic processGO:000907290.068
fatty acid metabolic processGO:0006631990.067
monocarboxylic acid metabolic processGO:00327871520.067
secretion by cellGO:00329402480.067
positive regulation of signalingGO:00230562700.066
homeostatic processGO:00425923310.066
cellular homeostasisGO:00197252520.066
response to molecule of fungal originGO:000223830.065
amino acid transportGO:0006865700.065
cellular response to organonitrogen compoundGO:00714171970.065
regulation of amine transportGO:0051952540.064
4 chlorobiphenyl metabolic processGO:001888010.063
chemical homeostasisGO:00488782920.063
nucleobase containing small molecule metabolic processGO:00550863160.062
ion homeostasisGO:00508012120.061
choline transportGO:001587140.060
reproductive processGO:00224143720.059
metal ion transportGO:00300012890.058
stress activated protein kinase signaling cascadeGO:0031098370.058
glutathione transportGO:003463520.058
regulation of secretion by cellGO:19035302080.056
renal sodium excretionGO:0035812200.056
cellular divalent inorganic cation homeostasisGO:00725031620.053
norepinephrine transportGO:0015874180.053
quaternary ammonium group transportGO:001569760.052
neurological system processGO:00508772190.052
ovulation cycleGO:0042698670.052
response to calcium ionGO:0051592590.052
toxin transportGO:190199830.050
lipid biosynthetic processGO:00086101280.050
organic hydroxy compound transportGO:0015850770.050
regulation of apoptotic processGO:00429813350.049
response to estradiolGO:00323551640.048
transmembrane transportGO:00550854120.048
cellular lipid metabolic processGO:00442552080.048
monocarboxylic acid transportGO:0015718520.047
response to insulinGO:00328681330.047
cellular response to alcoholGO:0097306870.047
positive regulation of nitrogen compound metabolic processGO:00511733340.047
cell migrationGO:00164771970.046
sodium independent organic anion transportGO:004325220.046
secretionGO:00469033070.046
response to mercury ionGO:0046689150.046
response to biotic stimulusGO:00096072260.045
signal transduction by phosphorylationGO:00230141440.045
steroid catabolic processGO:000670650.044
drug metabolic processGO:0017144110.044
cellular catabolic processGO:00442482950.044
single organism biosynthetic processGO:00447113420.043
anion transportGO:00068201780.043
cellular chemical homeostasisGO:00550822470.042
organic substance catabolic processGO:19015753160.042
regulation of cellular localizationGO:00603412630.042
positive regulation of transportGO:00510502450.042
antibiotic transportGO:004289120.041
response to organophosphorusGO:00466831020.041
positive regulation of biosynthetic processGO:00098913190.041
organic cyclic compound catabolic processGO:19013611750.041
multicellular organismal reproductive processGO:00486092330.040
positive regulation of response to stimulusGO:00485842850.040
single organism reproductive processGO:00447022970.039
oxidative demethylationGO:007098920.039
smooth muscle cell proliferationGO:0048659770.039
cellular ion homeostasisGO:00068731840.039
negative regulation of cell deathGO:00605482290.039
regulation of hormone secretionGO:00468831060.039
ion transmembrane transportGO:00342203650.039
cellular component assemblyGO:00226073600.038
rhythmic processGO:00485111560.038
single organism catabolic processGO:00447122830.038
hormone metabolic processGO:0042445690.037
unsaturated fatty acid metabolic processGO:0033559390.037
secondary metabolic processGO:0019748150.037
apoptotic processGO:00069153810.036
cellular response to growth factor stimulusGO:00713631620.036
long chain fatty acid metabolic processGO:0001676320.036
regulation of cell proliferationGO:00421273590.036
response to insecticideGO:0017085210.036
negative regulation of transportGO:00510511360.036
regulation of cellular amine metabolic processGO:003323880.036
cellular ketone metabolic processGO:0042180510.036
female pregnancyGO:00075651220.035
g protein coupled receptor signaling pathwayGO:00071862420.035
cellular response to xenobiotic stimulusGO:0071466190.035
regenerationGO:00310991630.035
response to estrogenGO:00436272320.035
immune effector processGO:0002252530.034
negative regulation of calcium ion importGO:009028120.034
sexual reproductionGO:00199531480.034
negative regulation of developmental processGO:00510931250.034
reproductionGO:00000032450.034
organ regenerationGO:00311001010.033
carboxylic acid transportGO:00469421150.033
regulation of phosphate metabolic processGO:00192203490.033
cellular response to ketoneGO:1901655510.033
cellular component movementGO:00069282480.033
lipid catabolic processGO:0016042460.033
cell cell signalingGO:00072673350.032
transcription dna templatedGO:00063513770.032
cation transportGO:00068123820.032
toxin metabolic processGO:000940490.032
amine metabolic processGO:0009308380.032
drug transportGO:0015893180.032
peptidyl tyrosine modificationGO:0018212720.032
naphthalene metabolic processGO:001893120.031
transcription from rna polymerase ii promoterGO:00063662520.031
growthGO:00400071650.031
intestinal absorptionGO:005089230.031
cognitionGO:0050890920.030
regulation of ion transportGO:00432692450.030
organic acid transportGO:00158491160.030
response to ammonium ionGO:0060359710.030
cation homeostasisGO:00550801950.030
inflammatory responseGO:00069541500.030
positive regulation of phosphorylationGO:00423271770.030
naphthalene containing compound metabolic processGO:009042020.030
positive regulation of cell communicationGO:00106472710.030
regulation of organic acid transportGO:0032890350.030
calcium ion importGO:0070509220.030
developmental growthGO:00485891000.029
regulation of rna biosynthetic processGO:20011413810.029
protein complex subunit organizationGO:00718223020.029
lipid transportGO:0006869610.029
protein homooligomerizationGO:0051260910.029
regulation of epithelial cell proliferationGO:0050678490.028
regulation of peptide transportGO:0090087870.028
cell motilityGO:00488702020.028
positive regulation of molecular functionGO:00440932300.028
regulation of immunoglobulin productionGO:000263740.027
epinephrine transportGO:004824170.027
positive regulation of protein phosphorylationGO:00019341350.027
circulatory system developmentGO:00723591340.026
muscle cell proliferationGO:0033002840.026
epithelial cell proliferationGO:0050673540.026
peptide transportGO:0015833970.026
tripeptide transportGO:004293920.026
sterol catabolic processGO:001612710.026
norepinephrine metabolic processGO:004241530.026
catecholamine transportGO:0051937370.026
activation of protein kinase activityGO:0032147470.025
negative regulation of multicellular organismal processGO:00512412030.025
head developmentGO:00603222470.025
regulation of neurogenesisGO:00507672470.025
single organism behaviorGO:00447081300.025
positive regulation of immune system processGO:0002684900.025
regulation of signal transductionGO:00099663180.025
coumarin catabolic processGO:004622630.025
carbohydrate derivative metabolic processGO:19011353460.025
positive regulation of signal transductionGO:00099671750.025
liver developmentGO:0001889900.025
regulation of blood circulationGO:19035221100.025
positive regulation of phosphorus metabolic processGO:00105622620.025
regulation of molecular functionGO:00650093980.024
cellular response to metal ionGO:0071248550.024
hepaticobiliary system developmentGO:0061008900.024
ribonucleotide metabolic processGO:00092592310.024
response to molecule of bacterial originGO:00022371940.024
cellular metal ion homeostasisGO:00068751720.024
regulation of reactive oxygen species biosynthetic processGO:190342650.024
programmed cell deathGO:00125013920.023
response to activityGO:0014823730.023
response to vitaminGO:00332731310.023
brain renin angiotensin systemGO:000203530.023
regulation of cell migrationGO:00303341280.023
central nervous system developmentGO:00074173110.023
regulation of cellular protein metabolic processGO:00322682670.023
positive regulation of cell deathGO:00109421840.022
digestive system processGO:0022600240.022
response to cadmium ionGO:0046686350.022
cellular response to peptideGO:19016531330.022
regulation of blood vessel sizeGO:0050880890.022
positive regulation of cellular amine metabolic processGO:003324030.022
alcohol metabolic processGO:0006066770.022
positive regulation of hormone secretionGO:0046887650.022
cellular hormone metabolic processGO:0034754490.022
positive regulation of cellular amino acid metabolic processGO:004576410.022
cellular nitrogen compound catabolic processGO:00442701630.022
brain developmentGO:00074202470.022
cellular amine metabolic processGO:0044106380.021
purine nucleotide metabolic processGO:00061632290.021
acid secretionGO:0046717480.021
phenylpropanoid catabolic processGO:004627130.021
digestionGO:0007586260.021
regulation of locomotionGO:00400121480.021
acetyl coa metabolic processGO:0006084170.021
peptidyl tyrosine phosphorylationGO:0018108720.021
metal ion homeostasisGO:00550651860.021
reactive nitrogen species metabolic processGO:200105710.020
fatty acid derivative metabolic processGO:1901568380.020
catabolic processGO:00090563510.020
localization of cellGO:00516742020.020
response to cocaineGO:0042220390.020
defense responseGO:00069521940.020
cellular response to nitrogen compoundGO:19016992100.020
negative regulation of secretionGO:0051048820.020
rna biosynthetic processGO:00327743800.020
negative regulation of apoptotic processGO:00430661810.020
calcium ion homeostasisGO:00550741620.020
regulation of neuron apoptotic processGO:0043523830.020
regulation of immune system processGO:00026821230.020
response to nicotineGO:0035094510.020
regulation of smooth muscle cell proliferationGO:0048660750.020
negative regulation of signalingGO:00230571570.020
regulation of cell differentiationGO:00455953200.020
regulation of peptide secretionGO:0002791820.020
response to transition metal nanoparticleGO:19902671220.019
positive regulation of catalytic activityGO:00430851840.019
regulation of catalytic activityGO:00507903040.019
regulation of cellular ketone metabolic processGO:0010565270.019
neural crest cell migrationGO:000175510.019
hormone catabolic processGO:004244720.019
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.019
regulation of transferase activityGO:00513381230.019
response to oxygen levelsGO:00704822650.019
hormone secretionGO:00468791150.019
negative regulation of neuron deathGO:1901215690.019
regulation of membrane potentialGO:00423911100.019
lipid localizationGO:0010876620.019
peptide secretionGO:0002790860.019
macromolecular complex subunit organizationGO:00439333390.019
nucleoside phosphate metabolic processGO:00067532830.019
anterior posterior pattern specificationGO:000995210.019
regulation of phosphorylationGO:00423252480.019
regulation of protein metabolic processGO:00512462890.019
regulation of system processGO:00440572080.018
organonitrogen compound catabolic processGO:19015651790.018
aromatic compound catabolic processGO:00194391680.018
regulation of ossificationGO:0030278320.018
tryptophan metabolic processGO:000656850.018
protein phosphorylationGO:00064683450.018
single organism intracellular transportGO:19025821660.018
positive regulation of cellular biosynthetic processGO:00313282950.018
regulation of tube sizeGO:0035150890.018
vesicle mediated transportGO:00161921810.018
response to temperature stimulusGO:0009266940.018
leukocyte activationGO:0045321760.018
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.018
positive regulation of leukocyte degranulationGO:004330240.018
epoxygenase p450 pathwayGO:001937310.018
regulation of neuron deathGO:19012141150.017
regulation of neuron differentiationGO:00456642080.017
regulation of synaptic transmissionGO:00508041410.017
regulation of blood pressureGO:0008217830.017
positive regulation of transcription dna templatedGO:00458931970.017
intracellular transportGO:00469071850.017
reactive oxygen species biosynthetic processGO:190340980.017
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
regulation of cellular component movementGO:00512701500.017
coenzyme metabolic processGO:0006732860.017
secondary alcohol metabolic processGO:190265220.017
regulation of neurological system processGO:0031644430.017
heterocycle catabolic processGO:00467001670.017
organophosphate catabolic processGO:00464341480.017
action potentialGO:0001508540.017
lymphocyte activationGO:0046649430.017
hepatocyte proliferationGO:007257430.017
regulation of response to woundingGO:1903034690.017
regulation of reactive oxygen species metabolic processGO:2000377260.016
acute inflammatory responseGO:0002526580.016
carnitine transportGO:001587910.016
tryptophan catabolic processGO:000656950.016
regulation of homeostatic processGO:00328441010.016
positive regulation of reactive oxygen species metabolic processGO:2000379160.016
angiotensin mediated drinking behaviorGO:000305120.016
purine ribonucleotide metabolic processGO:00091502270.016
response to woundingGO:00096112540.016
regulation of intracellular signal transductionGO:19025312180.016
purine containing compound metabolic processGO:00725212530.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
positive regulation of epithelial cell proliferationGO:0050679320.016
amine catabolic processGO:000931090.016
regulation of leukocyte activationGO:0002694450.016
divalent inorganic cation homeostasisGO:00725071650.016
cation transmembrane transportGO:00986552630.016
regulation of transcription dna templatedGO:00063553740.016
positive regulation of intracellular signal transductionGO:19025331380.016
catechol containing compound biosynthetic processGO:000971390.016
synaptic transmissionGO:00072682350.016
positive regulation of rna metabolic processGO:00512542030.016
estrogen metabolic processGO:0008210110.016
regulation of cellular amino acid metabolic processGO:000652120.016
nucleic acid templated transcriptionGO:00976593790.016
regulation of nucleotide metabolic processGO:00061401170.015
macromolecule localizationGO:00330362520.015
regulation of amino acid transportGO:0051955250.015
glycerolipid metabolic processGO:0046486670.015
regulation of body fluid levelsGO:0050878900.015
cytosolic calcium ion homeostasisGO:00514801400.015
cellular response to stressGO:00335542690.015
signal releaseGO:00230611450.015
ribose phosphate metabolic processGO:00196932350.015
response to dexamethasoneGO:0071548490.015
negative regulation of molecular functionGO:00440921330.015
limbic system developmentGO:0021761380.015
endocardial cushion developmentGO:000319710.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
regulation of nervous system developmentGO:00519602640.015
vitamin biosynthetic processGO:000911030.015
positive regulation of phosphate metabolic processGO:00459372620.015
response to purine containing compoundGO:00140741260.015
alcohol biosynthetic processGO:0046165380.015
4 nitrophenol metabolic processGO:001896010.015
sorbitol metabolic processGO:000606010.015
reactive oxygen species metabolic processGO:0072593370.015
regulation of norepinephrine secretionGO:0014061150.015
androgen metabolic processGO:0008209140.014
catecholamine metabolic processGO:0006584190.014
cellular biogenic amine catabolic processGO:004240290.014
positive regulation of immunoglobulin productionGO:000263940.014
vasoconstrictionGO:0042310540.014
forebrain developmentGO:0030900980.014
protein complex biogenesisGO:00702712630.014
defense response to gram negative bacteriumGO:005082930.014
positive regulation of protein kinase activityGO:0045860730.014
cellular response to reactive oxygen speciesGO:0034614550.014
positive regulation of cell proliferationGO:00082842490.014
regulation of growthGO:00400081050.014
spermatogenesisGO:0007283990.014
cell activationGO:0001775970.014
regulation of response to external stimulusGO:00321011060.014
response to lipopolysaccharideGO:00324961910.014
cellular response to campGO:0071320260.013
cellular response to inorganic substanceGO:0071241650.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
multicellular organismal response to stressGO:0033555250.013
bile acid and bile salt transportGO:0015721120.013
regulation of defense responseGO:0031347680.013
regulation of rna metabolic processGO:00512523910.013
positive regulation of blood circulationGO:1903524650.013
regulation of excretionGO:0044062210.013
positive regulation of nervous system developmentGO:00519621780.013
thyroid hormone metabolic processGO:004240340.013
blood vessel morphogenesisGO:0048514580.013
positive regulation of renal sodium excretionGO:0035815100.013
regulation of insulin secretionGO:0050796650.013
male gamete generationGO:0048232990.013
diterpenoid metabolic processGO:0016101330.013
negative regulation of cell differentiationGO:0045596990.013
positive regulation of protein metabolic processGO:00512471780.013
catecholamine secretionGO:0050432330.013
response to cytokineGO:00340972150.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
erk1 and erk2 cascadeGO:0070371480.013
positive regulation of developmental processGO:00510942830.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
response to amphetamineGO:0001975250.013
memoryGO:0007613540.013
purine ribonucleoside catabolic processGO:00461301240.013
catechol containing compound metabolic processGO:0009712190.012
insulin secretionGO:0030073690.012
polyol biosynthetic processGO:0046173130.012
regulation of acute inflammatory responseGO:0002673230.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.012
response to heatGO:0009408600.012
response to hypoxiaGO:00016662310.012
acute phase responseGO:0006953200.012
regulation of metal ion transportGO:00109591180.012
fatty acid derivative transportGO:1901571150.012
hormone biosynthetic processGO:0042446250.012
feeding behaviorGO:0007631530.012
negative regulation of programmed cell deathGO:00430691830.012
vasculature developmentGO:0001944700.012
cofactor metabolic processGO:0051186950.012
small gtpase mediated signal transductionGO:0007264360.012
arachidonic acid metabolic processGO:0019369200.012
negative regulation of nervous system developmentGO:0051961790.012
response to radiationGO:00093141370.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
response to amineGO:0014075460.012
positive regulation of transferase activityGO:0051347810.012
regulation of multicellular organismal developmentGO:20000263760.012
muscle contractionGO:0006936880.012
jak stat cascadeGO:0007259260.011
xenobiotic metabolic processGO:0006805190.011
multicellular organism reproductionGO:00325042330.011
regulation of muscle system processGO:0090257790.011
cellular component biogenesisGO:00440853680.011
nucleotide metabolic processGO:00091172790.011
exocytosisGO:0006887600.011
regulation of serine type peptidase activityGO:190257110.011
regulation of anion transportGO:0044070430.011
lipid storageGO:001991510.011
regulation of defecationGO:200029210.011
fat soluble vitamin biosynthetic processGO:004236220.011
regulation of renal sodium excretionGO:0035813200.011
response to decreased oxygen levelsGO:00362932370.011
single organism carbohydrate metabolic processGO:00447231180.011
protein oligomerizationGO:00512591910.011
agingGO:00075682410.011
mapk cascadeGO:00001651400.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
response to corticosteroneGO:0051412400.011
protein transportGO:00150311320.011
regulation of anatomical structure morphogenesisGO:00226031410.011
negative regulation of proteolysisGO:0045861410.011
vitamin d3 metabolic processGO:007064020.011
cellular modified amino acid metabolic processGO:0006575610.011
polyol metabolic processGO:0019751200.011
testosterone biosynthetic processGO:006137050.011
regulation of organ formationGO:000315620.011
response to hydrogen peroxideGO:0042542890.010
multicellular organism growthGO:003526410.010
organophosphate metabolic processGO:00196373700.010

Slco1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.035
disease of metabolismDOID:001466700.035
cardiovascular system diseaseDOID:128700.030
hypertensionDOID:1076300.030
essential hypertensionDOID:1082500.030
disease of anatomical entityDOID:700.030
artery diseaseDOID:005082800.030
vascular diseaseDOID:17800.030
steroid inherited metabolic disorderDOID:170100.010
lipid metabolism disorderDOID:314600.010
congenital adrenal hyperplasiaDOID:005081100.010