| organophosphate metabolic process | GO:0019637 | 370 | 0.210 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.080 | |
| cellular lipid metabolic process | GO:0044255 | 208 | 0.062 | |
| lipid metabolic process | GO:0006629 | 283 | 0.062 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 242 | 0.058 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.057 | |
| regulation of molecular function | GO:0065009 | 398 | 0.050 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.049 | |
| transmembrane transport | GO:0055085 | 412 | 0.049 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.042 | Fly |
| positive regulation of gene expression | GO:0010628 | 244 | 0.039 | Human Mouse Worm Fly |
| single organism biosynthetic process | GO:0044711 | 342 | 0.038 | |
| neuron differentiation | GO:0030182 | 368 | 0.038 | Human Mouse Worm Fly |
| negative regulation of transport | GO:0051051 | 136 | 0.038 | |
| regulation of catecholamine secretion | GO:0050433 | 32 | 0.038 | |
| catabolic process | GO:0009056 | 351 | 0.038 | |
| reproductive process | GO:0022414 | 372 | 0.037 | |
| head development | GO:0060322 | 247 | 0.037 | Zebrafish Mouse Fly |
| nucleotide metabolic process | GO:0009117 | 279 | 0.036 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.033 | Human Mouse Worm Fly |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.032 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.032 | |
| rhythmic process | GO:0048511 | 156 | 0.032 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.031 | |
| blood circulation | GO:0008015 | 183 | 0.030 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.029 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.029 | Human Mouse Worm Fly |
| single organism catabolic process | GO:0044712 | 283 | 0.028 | |
| regulation of hormone levels | GO:0010817 | 187 | 0.028 | |
| organophosphate biosynthetic process | GO:0090407 | 143 | 0.027 | |
| central nervous system development | GO:0007417 | 311 | 0.027 | Zebrafish Mouse Fly |
| cellular component biogenesis | GO:0044085 | 368 | 0.027 | Human |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.027 | Human Mouse Worm Fly |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.026 | Human Mouse Worm Fly |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.026 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.026 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.026 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.026 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.025 | Fly |
| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.025 | |
| regulation of sodium ion transmembrane transporter activity | GO:2000649 | 4 | 0.025 | |
| cellular ion homeostasis | GO:0006873 | 184 | 0.025 | |
| cellular calcium ion homeostasis | GO:0006874 | 160 | 0.025 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 153 | 0.025 | Fly |
| neuron development | GO:0048666 | 286 | 0.025 | Human Fly |
| organonitrogen compound biosynthetic process | GO:1901566 | 167 | 0.024 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.024 | |
| hormone transport | GO:0009914 | 121 | 0.024 | |
| cellular catabolic process | GO:0044248 | 295 | 0.024 | |
| single organism reproductive process | GO:0044702 | 297 | 0.023 | |
| tissue development | GO:0009888 | 252 | 0.023 | Zebrafish Mouse Fly |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.023 | |
| glycerolipid metabolic process | GO:0046486 | 67 | 0.023 | |
| apoptotic process | GO:0006915 | 381 | 0.023 | |
| amine metabolic process | GO:0009308 | 38 | 0.023 | |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.022 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.022 | Human Mouse Worm Fly |
| phototransduction visible light | GO:0007603 | 2 | 0.022 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.022 | Fly |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.022 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.022 | Human Mouse Worm Fly |
| regulation of ion transmembrane transport | GO:0034765 | 121 | 0.021 | |
| inorganic ion transmembrane transport | GO:0098660 | 229 | 0.021 | |
| growth | GO:0040007 | 165 | 0.021 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.021 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.021 | Fly |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.021 | Zebrafish |
| response to monosaccharide | GO:0034284 | 159 | 0.021 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.021 | |
| positive regulation of cell death | GO:0010942 | 184 | 0.021 | |
| organic hydroxy compound metabolic process | GO:1901615 | 115 | 0.021 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.021 | |
| brain development | GO:0007420 | 247 | 0.020 | Zebrafish Mouse Fly |
| inorganic cation transmembrane transport | GO:0098662 | 202 | 0.020 | |
| ribonucleotide biosynthetic process | GO:0009260 | 85 | 0.020 | |
| eye morphogenesis | GO:0048592 | 4 | 0.020 | Mouse Fly |
| circulatory system process | GO:0003013 | 183 | 0.020 | |
| cellular homeostasis | GO:0019725 | 252 | 0.020 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.020 | |
| regulation of nucleotide metabolic process | GO:0006140 | 117 | 0.019 | |
| hormone secretion | GO:0046879 | 115 | 0.019 | |
| organ morphogenesis | GO:0009887 | 75 | 0.019 | Mouse Fly |
| sex differentiation | GO:0007548 | 113 | 0.019 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 115 | 0.019 | |
| organophosphate catabolic process | GO:0046434 | 148 | 0.019 | |
| regulation of transporter activity | GO:0032409 | 50 | 0.019 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.019 | Human Mouse Worm Fly |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.019 | |
| single organism carbohydrate metabolic process | GO:0044723 | 118 | 0.019 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.019 | Fly |
| sodium ion transmembrane transport | GO:0035725 | 67 | 0.018 | |
| gland development | GO:0048732 | 155 | 0.018 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.018 | |
| purine nucleotide catabolic process | GO:0006195 | 136 | 0.018 | |
| behavior | GO:0007610 | 205 | 0.018 | Worm |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.018 | |
| nucleobase containing compound catabolic process | GO:0034655 | 152 | 0.018 | |
| alcohol metabolic process | GO:0006066 | 77 | 0.018 | |
| camp metabolic process | GO:0046058 | 63 | 0.018 | |
| rna metabolic process | GO:0016070 | 406 | 0.018 | Human Mouse Worm Fly |
| response to nutrient levels | GO:0031667 | 370 | 0.017 | |
| response to peptide | GO:1901652 | 292 | 0.017 | |
| axis specification | GO:0009798 | 4 | 0.017 | Mouse |
| heterocycle catabolic process | GO:0046700 | 167 | 0.017 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.017 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.017 | Fly |
| negative regulation of gene expression | GO:0010629 | 199 | 0.017 | Fly |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.017 | |
| male sex differentiation | GO:0046661 | 64 | 0.016 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.016 | Fly |
| regulation of signal transduction | GO:0009966 | 318 | 0.016 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.016 | |
| cellular metal ion homeostasis | GO:0006875 | 172 | 0.016 | |
| response to metal ion | GO:0010038 | 253 | 0.016 | |
| organ formation | GO:0048645 | 3 | 0.016 | |
| response to ethanol | GO:0045471 | 162 | 0.016 | |
| development of primary sexual characteristics | GO:0045137 | 107 | 0.016 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 81 | 0.016 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.016 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 124 | 0.016 | |
| reproductive system development | GO:0061458 | 128 | 0.016 | |
| response to radiation | GO:0009314 | 137 | 0.016 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.016 | Human Mouse Worm Fly |
| organelle organization | GO:0006996 | 266 | 0.016 | Fly |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.016 | Human Mouse Worm Fly |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 141 | 0.016 | |
| regulation of cyclic nucleotide biosynthetic process | GO:0030802 | 45 | 0.016 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.016 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.016 | Fly |
| cellular response to peptide hormone stimulus | GO:0071375 | 120 | 0.016 | |
| purine ribonucleotide catabolic process | GO:0009154 | 136 | 0.016 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.015 | Human Mouse Worm Fly |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.015 | |
| secretion by cell | GO:0032940 | 248 | 0.015 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.015 | |
| reproductive structure development | GO:0048608 | 128 | 0.015 | |
| gonad development | GO:0008406 | 104 | 0.015 | |
| phospholipid metabolic process | GO:0006644 | 61 | 0.015 | |
| response to ketone | GO:1901654 | 182 | 0.015 | |
| metal ion transport | GO:0030001 | 289 | 0.015 | |
| oxidation reduction process | GO:0055114 | 304 | 0.015 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.015 | Human |
| purine containing compound biosynthetic process | GO:0072522 | 85 | 0.015 | |
| regulation of peptide transport | GO:0090087 | 87 | 0.015 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 51 | 0.015 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 41 | 0.015 | |
| calcium ion transmembrane transport | GO:0070588 | 70 | 0.015 | |
| forebrain development | GO:0030900 | 98 | 0.015 | Mouse |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.015 | |
| chemical homeostasis | GO:0048878 | 292 | 0.014 | |
| response to camp | GO:0051591 | 91 | 0.014 | |
| nucleoside phosphate catabolic process | GO:1901292 | 140 | 0.014 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.014 | Fly |
| regulation of secretion | GO:0051046 | 224 | 0.014 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.014 | |
| single organism behavior | GO:0044708 | 130 | 0.014 | Worm |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.014 | |
| cellular carbohydrate metabolic process | GO:0044262 | 72 | 0.014 | |
| heart morphogenesis | GO:0003007 | 3 | 0.014 | |
| regulation of metal ion transport | GO:0010959 | 118 | 0.014 | |
| retina morphogenesis in camera type eye | GO:0060042 | 1 | 0.014 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.014 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 102 | 0.014 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.014 | |
| ribonucleoside metabolic process | GO:0009119 | 174 | 0.014 | |
| negative regulation of molecular function | GO:0044092 | 133 | 0.014 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.014 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.014 | Human Mouse Worm Fly |
| cytosolic calcium ion homeostasis | GO:0051480 | 140 | 0.014 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.014 | Human |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.014 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.013 | Human Mouse Worm Fly |
| ovulation cycle process | GO:0022602 | 50 | 0.013 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 117 | 0.013 | Fly |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.013 | |
| guanosine containing compound metabolic process | GO:1901068 | 74 | 0.013 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.013 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 75 | 0.013 | Fly |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.013 | Human Mouse Worm Fly |
| purine containing compound catabolic process | GO:0072523 | 138 | 0.013 | |
| sodium ion transport | GO:0006814 | 82 | 0.013 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.013 | Fly |
| embryonic appendage morphogenesis | GO:0035113 | 4 | 0.013 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.013 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.013 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.013 | Mouse Fly |
| monovalent inorganic cation transport | GO:0015672 | 172 | 0.013 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.012 | |
| embryonic limb morphogenesis | GO:0030326 | 4 | 0.012 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.012 | |
| calcium ion homeostasis | GO:0055074 | 162 | 0.012 | |
| regulation of secretion by cell | GO:1903530 | 208 | 0.012 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 91 | 0.012 | |
| sensory organ development | GO:0007423 | 74 | 0.012 | Zebrafish Mouse Fly |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 2 | 0.012 | |
| cyclic nucleotide metabolic process | GO:0009187 | 80 | 0.012 | |
| cellular response to lipid | GO:0071396 | 201 | 0.012 | |
| aromatic compound catabolic process | GO:0019439 | 168 | 0.012 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.012 | |
| sensory perception | GO:0007600 | 101 | 0.012 | Worm |
| cation transport | GO:0006812 | 382 | 0.012 | |
| camp biosynthetic process | GO:0006171 | 47 | 0.012 | |
| regeneration | GO:0031099 | 163 | 0.012 | |
| positive regulation of apoptotic process | GO:0043065 | 154 | 0.012 | |
| response to wounding | GO:0009611 | 254 | 0.012 | |
| adult locomotory behavior | GO:0008344 | 4 | 0.012 | |
| developmental growth | GO:0048589 | 100 | 0.012 | |
| cyclic nucleotide biosynthetic process | GO:0009190 | 63 | 0.012 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.012 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.012 | |
| sequestering of metal ion | GO:0051238 | 9 | 0.012 | |
| peptide transport | GO:0015833 | 97 | 0.011 | |
| camera type eye morphogenesis | GO:0048593 | 2 | 0.011 | |
| regulation of vesicle mediated transport | GO:0060627 | 81 | 0.011 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.011 | |
| regulation of peptide secretion | GO:0002791 | 82 | 0.011 | |
| limb morphogenesis | GO:0035108 | 4 | 0.011 | |
| nucleotide catabolic process | GO:0009166 | 139 | 0.011 | |
| regulation of neuron death | GO:1901214 | 115 | 0.011 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.011 | Human Mouse Worm Fly |
| cell cell signaling | GO:0007267 | 335 | 0.011 | |
| response to reactive oxygen species | GO:0000302 | 120 | 0.011 | |
| hormone metabolic process | GO:0042445 | 69 | 0.011 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.011 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.011 | |
| response to organophosphorus | GO:0046683 | 102 | 0.011 | |
| phospholipase c activating g protein coupled receptor signaling pathway | GO:0007200 | 27 | 0.011 | |
| peptide hormone secretion | GO:0030072 | 84 | 0.011 | |
| gliogenesis | GO:0042063 | 93 | 0.011 | |
| endocrine system development | GO:0035270 | 30 | 0.011 | |
| reproduction | GO:0000003 | 245 | 0.011 | |
| embryonic axis specification | GO:0000578 | 1 | 0.011 | Mouse |
| intracellular transport | GO:0046907 | 185 | 0.011 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.011 | |
| cellular component movement | GO:0006928 | 248 | 0.011 | Human |
| purine nucleoside metabolic process | GO:0042278 | 169 | 0.011 | |
| amide transport | GO:0042886 | 105 | 0.011 | |
| ribonucleoside catabolic process | GO:0042454 | 126 | 0.011 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.011 | Human Mouse Worm Fly |
| cell migration | GO:0016477 | 197 | 0.011 | |
| response to purine containing compound | GO:0014074 | 126 | 0.011 | |
| neuromuscular process | GO:0050905 | 2 | 0.011 | |
| regulation of insulin secretion | GO:0050796 | 65 | 0.011 | |
| negative regulation of secretion | GO:0051048 | 82 | 0.011 | |
| programmed cell death | GO:0012501 | 392 | 0.011 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.010 | Fly |
| response to peptide hormone | GO:0043434 | 278 | 0.010 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.010 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.010 | Fly |
| response to light stimulus | GO:0009416 | 52 | 0.010 | |
| neural crest cell development | GO:0014032 | 2 | 0.010 | |
| gastrulation | GO:0007369 | 2 | 0.010 | Mouse |
| heart development | GO:0007507 | 72 | 0.010 | |
| gtp metabolic process | GO:0046039 | 72 | 0.010 | |
| sequestering of calcium ion | GO:0051208 | 8 | 0.010 | |
| carbohydrate metabolic process | GO:0005975 | 130 | 0.010 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.010 | |
| cell fate determination | GO:0001709 | 2 | 0.010 | Mouse |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.010 | |
| nucleotide biosynthetic process | GO:0009165 | 98 | 0.010 | |
| development of primary female sexual characteristics | GO:0046545 | 56 | 0.010 | |
| regulation of gtp catabolic process | GO:0033124 | 58 | 0.010 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.010 | |
| gtp catabolic process | GO:0006184 | 71 | 0.010 | |
| regulation of cell development | GO:0060284 | 263 | 0.010 | Fly |