Rattus norvegicus

25 known processes

Scnn1a

sodium channel, nonvoltage-gated 1 alpha

Scnn1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
localization of cellGO:00516742020.330
Rat
cation transportGO:00068123820.323
monovalent inorganic cation transportGO:00156721720.290
circulatory system processGO:00030131830.262
neurological system processGO:00508772190.204
Fly
response to monosaccharideGO:00342841590.204
response to carbohydrateGO:00097431830.195
regulation of system processGO:00440572080.180
cellular chemical homeostasisGO:00550822470.173
blood circulationGO:00080151830.166
response to estradiolGO:00323551640.155
response to hexoseGO:00097461440.149
macromolecular complex subunit organizationGO:00439333390.149
heart contractionGO:0060047570.142
positive regulation of multicellular organismal processGO:00512403870.142
regulation of anatomical structure morphogenesisGO:00226031410.141
metal ion transportGO:00300012890.138
cellular homeostasisGO:00197252520.136
heart processGO:0003015570.136
anatomical structure morphogenesisGO:00096532980.135
Rat Worm
protein complex biogenesisGO:00702712630.134
cell cell signalingGO:00072673350.130
Fly
wound healingGO:00420601220.128
Rat
response to mechanical stimulusGO:00096121340.125
Worm Fly
cation transmembrane transportGO:00986552630.122
agingGO:00075682410.122
response to nutrient levelsGO:00316673700.119
response to metal ionGO:00100382530.119
regulation of multicellular organismal developmentGO:20000263760.117
response to decreased oxygen levelsGO:00362932370.112
Rat
growthGO:00400071650.110
Worm
protein complex subunit organizationGO:00718223020.110
response to extracellular stimulusGO:00099913800.109
regulation of blood vessel sizeGO:0050880890.108
homeostatic processGO:00425923310.108
Human
response to nutrientGO:00075842480.107
defense responseGO:00069521940.105
ion homeostasisGO:00508012120.101
Human
inorganic ion transmembrane transportGO:00986602290.100
response to ketoneGO:19016541820.099
rna biosynthetic processGO:00327743800.099
regulation of neurogenesisGO:00507672470.088
single organism behaviorGO:00447081300.088
Worm Fly
vascular process in circulatory systemGO:0003018960.081
positive regulation of developmental processGO:00510942830.081
regulation of blood circulationGO:19035221100.080
response to oxygen levelsGO:00704822650.078
Rat
nucleic acid templated transcriptionGO:00976593790.078
protein complex assemblyGO:00064612630.078
sodium ion transportGO:0006814820.077
regulation of rna biosynthetic processGO:20011413810.076
nitrogen compound transportGO:00717052290.076
circulatory system developmentGO:00723591340.075
circadian rhythmGO:0007623880.074
regulation of cellular localizationGO:00603412630.072
carbohydrate homeostasisGO:0033500750.072
regulation of signal transductionGO:00099663180.071
response to inorganic substanceGO:00100353770.071
Fly
gland developmentGO:00487321550.070
immune system processGO:00023762040.069
cation homeostasisGO:00550801950.069
Human
inorganic cation transmembrane transportGO:00986622020.069
transcription from rna polymerase ii promoterGO:00063662520.067
regulation of molecular functionGO:00650093980.067
multicellular organismal signalingGO:0035637440.067
positive regulation of blood circulationGO:1903524650.067
chemical homeostasisGO:00488782920.064
Human
response to temperature stimulusGO:0009266940.064
Fly
regulation of transcription dna templatedGO:00063553740.064
multi organism reproductive processGO:00447032620.063
Worm Fly
positive regulation of nervous system developmentGO:00519621780.063
regulation of tube sizeGO:0035150890.062
negative regulation of macromolecule metabolic processGO:00106052600.062
organ morphogenesisGO:0009887750.062
positive regulation of cell developmentGO:00107201760.062
response to hypoxiaGO:00016662310.061
Rat
transcription dna templatedGO:00063513770.061
biological adhesionGO:00226101100.060
protein oligomerizationGO:00512591910.060
cellular response to stressGO:00335542690.060
cellular component movementGO:00069282480.059
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.059
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.058
regulation of blood pressureGO:0008217830.058
regulation of cell differentiationGO:00455953200.058
regulation of cellular component movementGO:00512701500.058
positive regulation of response to stimulusGO:00485842850.057
cellular component assemblyGO:00226073600.057
rna metabolic processGO:00160704060.056
reproductive processGO:00224143720.054
Worm Fly
regulation of anatomical structure sizeGO:00900661350.054
glucose homeostasisGO:0042593750.053
response to glucoseGO:00097491360.052
regulation of metal ion transportGO:00109591180.050
Rat
regulation of nervous system developmentGO:00519602640.050
protein homooligomerizationGO:0051260910.049
metal ion homeostasisGO:00550651860.049
Human
cell communication involved in cardiac conductionGO:008606520.049
regulation of response to stressGO:00801341260.048
regulation of cell migrationGO:00303341280.048
response to woundingGO:00096112540.048
Rat
head developmentGO:00603222470.048
positive regulation of transportGO:00510502450.048
endocytosisGO:0006897840.048
positive regulation of cell differentiationGO:00455972170.047
cellular cation homeostasisGO:00300031800.047
rhythmic processGO:00485111560.047
macromolecular complex assemblyGO:00650032730.047
response to biotic stimulusGO:00096072260.046
regulation of immune system processGO:00026821230.046
ion transmembrane transportGO:00342203650.045
action potentialGO:0001508540.045
epiboly involved in wound healingGO:009050520.045
Rat
regulation of cellular component organizationGO:00511283680.045
single organism reproductive processGO:00447022970.045
Worm
feeding behaviorGO:0007631530.044
Fly
camp metabolic processGO:0046058630.044
positive regulation of nitrogen compound metabolic processGO:00511733340.043
positive regulation of epidermis developmentGO:004568410.043
urogenital system developmentGO:0001655780.042
negative regulation of response to stimulusGO:00485851550.042
Worm Fly
regulation of vasculature developmentGO:1901342440.042
cardiovascular system developmentGO:00723581340.042
response to corticosteroidGO:00319602350.041
response to lipopolysaccharideGO:00324961910.041
negative regulation of cell developmentGO:0010721820.041
response to acid chemicalGO:00011012220.041
Worm Fly
cellular ion homeostasisGO:00068731840.040
central nervous system developmentGO:00074173110.040
muscle system processGO:00030121150.040
tissue developmentGO:00098882520.040
Rat
neuron differentiationGO:00301823680.039
catabolic processGO:00090563510.039
programmed cell deathGO:00125013920.039
regulation of rna metabolic processGO:00512523910.039
regulation of cell proliferationGO:00421273590.039
positive regulation of heart contractionGO:0045823150.039
response to external biotic stimulusGO:00432072210.038
vesicle mediated transportGO:00161921810.038
regulation of locomotionGO:00400121480.037
regulation of heart contractionGO:0008016480.037
positive regulation of gene expressionGO:00106282440.037
positive regulation of cell motilityGO:2000147970.037
negative regulation of cell communicationGO:00106481580.037
cellular response to abiotic stimulusGO:0071214850.037
Fly
regulation of cell motilityGO:20001451310.036
positive regulation of biosynthetic processGO:00098913190.036
striated muscle contractionGO:0006941440.036
regulation of neuron differentiationGO:00456642080.035
regulation of cell growthGO:0001558850.035
transmembrane transportGO:00550854120.034
secretionGO:00469033070.034
sexual reproductionGO:00199531480.034
Worm Fly
regulation of nucleic acid templated transcriptionGO:19035063800.034
isoprenoid metabolic processGO:0006720450.034
response to bacteriumGO:00096172000.033
behaviorGO:00076102050.033
Worm Fly
regulation of cell morphogenesis involved in differentiationGO:0010769720.033
regulation of secretionGO:00510462240.033
regulation of response to woundingGO:1903034690.033
negative regulation of metabolic processGO:00098923310.032
response to increased oxygen levelsGO:0036296450.032
regulation of cell developmentGO:00602842630.032
cell migrationGO:00164771970.032
Rat
neuron developmentGO:00486662860.032
heart morphogenesisGO:000300730.031
liver developmentGO:0001889900.031
negative regulation of developmental processGO:00510931250.031
intracellular signal transductionGO:00355563140.030
regulation of stem cell differentiationGO:200073620.029
transmission of nerve impulseGO:0019226420.029
carbohydrate metabolic processGO:00059751300.029
divalent metal ion transportGO:00708381320.029
Worm
positive regulation of rna metabolic processGO:00512542030.029
cellular component biogenesisGO:00440853680.029
response to mineralocorticoidGO:0051385490.029
synaptic transmissionGO:00072682350.029
Fly
cellular response to hexose stimulusGO:0071331650.029
positive regulation of cytosolic calcium ion concentrationGO:00072041220.029
positive regulation of rna biosynthetic processGO:19026801970.028
locomotionGO:00400112370.028
Rat Worm
kidney developmentGO:0001822670.028
enzyme linked receptor protein signaling pathwayGO:00071671160.028
oxoacid metabolic processGO:00434362900.027
hormone metabolic processGO:0042445690.027
positive regulation of cellular biosynthetic processGO:00313282950.027
sensory perceptionGO:00076001010.027
Fly
multicellular organism reproductionGO:00325042330.027
Worm Fly
response to activityGO:0014823730.027
cellular amino acid metabolic processGO:00065201070.027
cell projection organizationGO:00300303020.027
inflammatory responseGO:00069541500.026
cellular response to glucose stimulusGO:0071333650.026
neuronal action potentialGO:0019228350.026
cognitionGO:0050890920.026
positive regulation of cellular component movementGO:00512721020.026
gliogenesisGO:0042063930.026
regulation of body fluid levelsGO:0050878900.026
small gtpase mediated signal transductionGO:0007264360.025
cellular response to oxygen containing compoundGO:19017013860.025
Fly
negative regulation of feeding behaviorGO:200025280.025
Fly
positive regulation of programmed cell deathGO:00430681570.025
regulation of intracellular transportGO:0032386650.025
organic acid metabolic processGO:00060822920.025
positive regulation of secretionGO:00510471400.025
regulation of catalytic activityGO:00507903040.025
secretion by cellGO:00329402480.025
positive regulation of transcription dna templatedGO:00458931970.025
response to testosteroneGO:0033574550.025
negative regulation of cell differentiationGO:0045596990.025
regulation of neurological system processGO:0031644430.025
regulation of defense responseGO:0031347680.024
cellular response to hormone stimulusGO:00328702470.024
calcium ion homeostasisGO:00550741620.024
cardiac conductionGO:006133720.024
proteolysisGO:00065081750.024
multi multicellular organism processGO:00447061380.024
Worm Fly
ensheathment of neuronsGO:0007272400.023
thyroid gland developmentGO:003087810.023
single organism catabolic processGO:00447122830.023
oxidation reduction processGO:00551143040.023
circadian regulation of gene expressionGO:003292230.023
regulation of vasodilationGO:0042312360.022
maintenance of locationGO:0051235170.022
cell motilityGO:00488702020.022
Rat
anatomical structure formation involved in morphogenesisGO:0048646830.022
negative regulation of multicellular organismal metabolic processGO:004425240.022
wound healing spreading of cellsGO:004431920.021
Rat
regulation of cellular amino acid metabolic processGO:000652120.021
jak stat cascadeGO:0007259260.021
positive regulation of cellular component organizationGO:00511302000.021
cell growthGO:00160491040.021
chemotaxisGO:0006935660.021
sequestering of calcium ionGO:005120880.021
response to peptide hormoneGO:00434342780.021
negative regulation of cell proliferationGO:00082851190.021
regulation of immune response to tumor cellGO:000283730.021
sodium ion homeostasisGO:0055078230.021
Human
regulation of response to external stimulusGO:00321011060.020
regulation of cellular response to stressGO:0080135490.020
brain developmentGO:00074202470.020
ras protein signal transductionGO:0007265290.020
apoptotic processGO:00069153810.020
negative regulation of cellular metabolic processGO:00313242810.020
g protein coupled receptor signaling pathwayGO:00071862420.020
positive regulation of neuron differentiationGO:00456661260.020
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.020
negative regulation of multicellular organismal processGO:00512412030.020
Worm
divalent inorganic cation homeostasisGO:00725071650.020
response to radiationGO:00093141370.020
positive regulation of cell growthGO:0030307440.020
organonitrogen compound biosynthetic processGO:19015661670.020
positive regulation of locomotionGO:00400171020.019
positive regulation of ion transportGO:0043270940.019
renal system developmentGO:0072001670.019
positive regulation of cell deathGO:00109421840.019
carbohydrate derivative metabolic processGO:19011353460.019
vasculature developmentGO:0001944700.019
regulation of apoptotic processGO:00429813350.019
neuron projection developmentGO:00311752730.019
negative regulation of transportGO:00510511360.019
cellular calcium ion homeostasisGO:00068741600.019
sequestering of metal ionGO:005123890.019
organelle organizationGO:00069962660.018
cell chemotaxisGO:0060326310.018
tube developmentGO:0035295890.018
intracellular transportGO:00469071850.018
positive regulation of signalingGO:00230562700.018
cellular catabolic processGO:00442482950.018
negative regulation of apoptotic processGO:00430661810.018
single organism cellular localizationGO:19025801020.018
response to glucocorticoidGO:00513842230.017
response to electrical stimulusGO:0051602560.017
positive regulation of angiogenesisGO:0045766280.017
negative regulation of gene expressionGO:00106291990.017
negative regulation of cell deathGO:00605482290.017
regulation of growthGO:00400081050.017
response to estrogenGO:00436272320.017
cellular response to carbohydrate stimulusGO:0071322720.017
actin filament based movementGO:0030048160.017
positive regulation of cell proliferationGO:00082842490.017
positive regulation of nucleotide biosynthetic processGO:0030810360.017
regulation of cellular ketone metabolic processGO:0010565270.017
cellular response to extracellular stimulusGO:0031668730.017
regulation of synaptic transmissionGO:00508041410.017
Fly
negative regulation of neuron differentiationGO:0045665620.017
reproductive structure developmentGO:00486081280.017
Worm
reproductionGO:00000032450.017
Worm Fly
multicellular organismal water homeostasisGO:005089140.017
Human
vasodilationGO:0042311440.017
regulation of ion transportGO:00432692450.016
Rat
response to molecule of bacterial originGO:00022371940.016
female pregnancyGO:00075651220.016
negative regulation of collagen biosynthetic processGO:003296640.016
regulation of muscle contractionGO:0006937530.016
regulation of cellular amine metabolic processGO:003323880.016
regulation of cyclic nucleotide biosynthetic processGO:0030802450.016
cellular response to insulin stimulusGO:0032869810.016
response to ethanolGO:00454711620.016
positive regulation of phosphorus metabolic processGO:00105622620.016
oligopeptide transportGO:000685740.016
receptor mediated endocytosisGO:0006898420.016
protein phosphorylationGO:00064683450.016
anion transmembrane transportGO:0098656770.016
regulation of sodium ion transportGO:0002028210.016
Rat
cell part morphogenesisGO:00329901230.016
epidermis developmentGO:0008544110.015
cytosolic calcium ion homeostasisGO:00514801400.015
regulation of striated muscle contractionGO:0006942210.015
cardiac muscle contractionGO:0060048270.015
single organism biosynthetic processGO:00447113420.015
cellular ketone metabolic processGO:0042180510.015
nucleoside phosphate biosynthetic processGO:19012931020.015
signal releaseGO:00230611450.015
negative regulation of signalingGO:00230571570.015
gonad developmentGO:00084061040.015
Worm
anterior posterior pattern specificationGO:000995210.015
regulation of epithelial cell proliferationGO:0050678490.015
response to vitaminGO:00332731310.015
positive regulation of secretion by cellGO:19035321280.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
positive regulation of protein metabolic processGO:00512471780.015
rho protein signal transductionGO:0007266110.015
metanephric tubule morphogenesisGO:007217320.015
cellular response to nitrogen compoundGO:19016992100.015
protein heterooligomerizationGO:0051291890.015
neuron deathGO:00709971270.015
regulation of calcium ion transportGO:0051924770.014
regulation of protein modification processGO:00313991940.014
female sex differentiationGO:0046660590.014
cellular amine metabolic processGO:0044106380.014
olfactory behaviorGO:004204820.014
gamete generationGO:00072761240.014
response to growth factorGO:00708481890.014
cellular modified amino acid metabolic processGO:0006575610.014
regulation of neuron projection developmentGO:00109751610.014
regulation of carbohydrate metabolic processGO:0006109410.014
gland morphogenesisGO:0022612120.014
cellular response to peptide hormone stimulusGO:00713751200.014
ossificationGO:0001503700.014
renal filtrationGO:0097205100.014
regulation of phosphorylationGO:00423252480.014
positive regulation of nucleotide metabolic processGO:0045981910.014
purine ribonucleotide biosynthetic processGO:0009152810.014
cell morphogenesisGO:00009021420.014
tissue regenerationGO:0042246360.014
cyclic nucleotide biosynthetic processGO:0009190630.013
multicellular organismal reproductive processGO:00486092330.013
Worm Fly
positive regulation of apoptotic processGO:00430651540.013
hepaticobiliary system developmentGO:0061008900.013
cell morphogenesis involved in differentiationGO:00009041190.013
regulation of behaviorGO:0050795610.013
Worm Fly
axis specificationGO:000979840.013
response to vitamin dGO:0033280340.013
olfactory learningGO:000835510.013
regulation of muscle system processGO:0090257790.013
taxisGO:0042330670.013
keratinocyte differentiationGO:003021620.013
positive regulation of potassium ion transportGO:0043268130.013
blood vessel developmentGO:0001568690.013
n methyl d aspartate receptor clusteringGO:009711420.012
developmental process involved in reproductionGO:00030061590.012
Worm
rhythmic behaviorGO:0007622240.012
positive regulation of behaviorGO:0048520380.012
cellular glucose homeostasisGO:0001678660.012
single organism organelle organizationGO:19025891800.012
ribose phosphate metabolic processGO:00196932350.012
negative regulation of programmed cell deathGO:00430691830.012
negative regulation of immune system processGO:0002683390.012
purine nucleotide biosynthetic processGO:0006164830.012
cellular response to endogenous stimulusGO:00714953770.012
sensory perception of painGO:0019233730.012
Fly
calcium ion transport into cytosolGO:0060402380.012
potassium ion transportGO:0006813970.012
respiratory system processGO:000301630.012
tissue morphogenesisGO:0048729220.012
Rat
neuromuscular synaptic transmissionGO:000727420.012
regulation of cell projection organizationGO:00313441750.012
regulation of neural precursor cell proliferationGO:2000177160.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
positive regulation of cytokine secretionGO:005071590.012
epithelial cell differentiation involved in kidney developmentGO:003585030.012
male mating behaviorGO:006017930.012
Worm Fly
positive regulation of signal transductionGO:00099671750.012
nucleoside monophosphate metabolic processGO:0009123930.012
spindle organizationGO:000705120.012
divalent inorganic cation transportGO:00725111340.012
Worm
positive regulation of cellular amine metabolic processGO:003324030.012
positive regulation of cellular catabolic processGO:0031331710.012
organophosphate metabolic processGO:00196373700.012
cell adhesionGO:00071551100.012
positive regulation of neurogenesisGO:00507691650.012
reproductive system developmentGO:00614581280.012
Worm
regulation of hormone levelsGO:00108171870.012
positive regulation of immune system processGO:0002684900.012
positive regulation of cyclic nucleotide metabolic processGO:0030801370.011
metanephric tubule developmentGO:007217040.011
carbohydrate derivative biosynthetic processGO:19011371240.011
nucleotide biosynthetic processGO:0009165980.011
negative regulation of growthGO:0045926370.011
single organism intracellular transportGO:19025821660.011
intracellular receptor signaling pathwayGO:0030522350.011
cellular response to external stimulusGO:00714961180.011
urinary tract smooth muscle contractionGO:001484840.011
regulation of amine transportGO:0051952540.011
developmental growthGO:00485891000.011
response to other organismGO:00517072200.011
regulation of sensory perception of painGO:0051930290.011
negative regulation of transcription regulatory region dna bindingGO:200067820.011
amine transportGO:0015837570.011
nucleobase containing small molecule metabolic processGO:00550863160.011
cellular nitrogen compound catabolic processGO:00442701630.011
response to cytokineGO:00340972150.011
regulation of protein localizationGO:0032880810.011
digestive tract developmentGO:0048565390.011
negative regulation of rna metabolic processGO:00512531230.011
regulation of phosphorus metabolic processGO:00511743490.011
response to fatty acidGO:0070542650.011
metanephric s shaped body morphogenesisGO:007228420.011
cellular protein localizationGO:00346131220.011
negative regulation of signal transductionGO:0009968830.011
negative regulation of cellular protein metabolic processGO:00322691060.011
embryonic morphogenesisGO:0048598140.011
response to transition metal nanoparticleGO:19902671220.011
response to tumor cellGO:000234740.011
response to alkaloidGO:00432791320.010
regulation of transmembrane transportGO:00347621220.010
gastrulationGO:000736920.010
carboxylic acid metabolic processGO:00197522890.010
prostate gland epithelium morphogenesisGO:006074020.010
regulation of synaptic plasticityGO:0048167700.010
mapk cascadeGO:00001651400.010
sleepGO:0030431300.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
organic substance catabolic processGO:19015753160.010
odontogenesisGO:0042476320.010
positive regulation of vasodilationGO:0045909290.010
locomotory exploration behaviorGO:003564110.010
response to anoxiaGO:003405940.010
cellular response to alcoholGO:0097306870.010
hormone secretionGO:00468791150.010
cell cycleGO:00070491010.010

Scnn1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.396
disease of anatomical entityDOID:700.396
Human
kidney diseaseDOID:55700.396
respiratory system diseaseDOID:157900.058
Human
lower respiratory tract diseaseDOID:005016100.058
Human
renal tubular transport diseaseDOID:44700.041
musculoskeletal system diseaseDOID:1700.018
connective tissue diseaseDOID:6500.018
bone diseaseDOID:008000100.015
bone development diseaseDOID:008000600.015
nervous system diseaseDOID:86300.010