Rattus norvegicus

17 known processes

Eef2k

eukaryotic elongation factor-2 kinase

(Aliases: SMEF2K)

Eef2k biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
programmed cell deathGO:00125013920.131
rna metabolic processGO:00160704060.116
regulation of phosphorus metabolic processGO:00511743490.106
regulation of cellular component organizationGO:00511283680.104
apoptotic processGO:00069153810.100
cellular response to oxygen containing compoundGO:19017013860.095
positive regulation of phosphate metabolic processGO:00459372620.094
regulation of protein metabolic processGO:00512462890.089
carboxylic acid metabolic processGO:00197522890.089
positive regulation of nucleobase containing compound metabolic processGO:00459353190.089
nucleic acid templated transcriptionGO:00976593790.087
regulation of cellular component movementGO:00512701500.086
positive regulation of nitrogen compound metabolic processGO:00511733340.085
regulation of cellular protein metabolic processGO:00322682670.082
positive regulation of cellular protein metabolic processGO:00322701670.080
vesicle mediated transportGO:00161921810.076
regulation of molecular functionGO:00650093980.074
regulation of transcription from rna polymerase ii promoterGO:00063572340.074
negative regulation of biosynthetic processGO:00098901680.072
rna biosynthetic processGO:00327743800.072
intracellular signal transductionGO:00355563140.071
cellular amino acid metabolic processGO:00065201070.069
transcription dna templatedGO:00063513770.069
cell migrationGO:00164771970.068
oxoacid metabolic processGO:00434362900.067
transcription from rna polymerase ii promoterGO:00063662520.066
regulation of nucleic acid templated transcriptionGO:19035063800.066
positive regulation of response to stimulusGO:00485842850.062
circulatory system developmentGO:00723591340.062
regulation of transferase activityGO:00513381230.061
regulation of cell developmentGO:00602842630.061
regulation of anatomical structure morphogenesisGO:00226031410.061
regulation of intracellular signal transductionGO:19025312180.060
cellular component movementGO:00069282480.060
organophosphate metabolic processGO:00196373700.059
macromolecular complex subunit organizationGO:00439333390.059
regulation of transcription dna templatedGO:00063553740.058
anatomical structure morphogenesisGO:00096532980.058
negative regulation of metabolic processGO:00098923310.058
protein complex subunit organizationGO:00718223020.057
establishment of protein localizationGO:00451841410.057
cellular response to endogenous stimulusGO:00714953770.056
single organism reproductive processGO:00447022970.056
protein phosphorylationGO:00064683450.055
catabolic processGO:00090563510.055
regulation of rna metabolic processGO:00512523910.055
protein complex biogenesisGO:00702712630.055
response to inorganic substanceGO:00100353770.054
regulation of cell differentiationGO:00455953200.054
organic acid metabolic processGO:00060822920.053
negative regulation of macromolecule metabolic processGO:00106052600.053
positive regulation of phosphorus metabolic processGO:00105622620.052
regulation of signal transductionGO:00099663180.052
regulation of rna biosynthetic processGO:20011413810.052
cellular ketone metabolic processGO:0042180510.051
reproductive processGO:00224143720.051
response to carbohydrateGO:00097431830.051
regulation of cell migrationGO:00303341280.051
regulation of multicellular organismal developmentGO:20000263760.050
secretionGO:00469033070.050
protein complex assemblyGO:00064612630.050
regulation of cellular ketone metabolic processGO:0010565270.048
regulation of phosphorylationGO:00423252480.048
regulation of cell proliferationGO:00421273590.048
negative regulation of transcription dna templatedGO:00458921160.048
response to acid chemicalGO:00011012220.047
single organism intracellular transportGO:19025821660.046
regulation of catalytic activityGO:00507903040.046
response to monosaccharideGO:00342841590.046
positive regulation of rna biosynthetic processGO:19026801970.045
single organism biosynthetic processGO:00447113420.045
regulation of kinase activityGO:00435491170.045
regulation of cellular amino acid metabolic processGO:000652120.045
negative regulation of gene expressionGO:00106291990.044
positive regulation of cellular biosynthetic processGO:00313282950.044
regulation of phosphate metabolic processGO:00192203490.043
carbohydrate metabolic processGO:00059751300.043
positive regulation of macromolecule biosynthetic processGO:00105572470.043
positive regulation of biosynthetic processGO:00098913190.043
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.043
cell motilityGO:00488702020.042
regulation of cellular amine metabolic processGO:003323880.042
macromolecular complex assemblyGO:00650032730.041
cellular amine metabolic processGO:0044106380.041
negative regulation of multicellular organismal processGO:00512412030.041
negative regulation of rna metabolic processGO:00512531230.041
response to hexoseGO:00097461440.040
negative regulation of nucleobase containing compound metabolic processGO:00459341530.040
regulation of cell motilityGO:20001451310.040
localization of cellGO:00516742020.040
cellular component biogenesisGO:00440853680.040
organelle organizationGO:00069962660.039
response to reactive oxygen speciesGO:00003021200.039
protein localizationGO:00081041910.039
positive regulation of molecular functionGO:00440932300.038
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.038
carbohydrate derivative metabolic processGO:19011353460.038
regulation of programmed cell deathGO:00430673410.038
central nervous system developmentGO:00074173110.037
regulation of apoptotic processGO:00429813350.037
single organism carbohydrate metabolic processGO:00447231180.037
locomotionGO:00400112370.037
cellular response to lipidGO:00713962010.037
positive regulation of signalingGO:00230562700.036
negative regulation of macromolecule biosynthetic processGO:00105581480.036
cellular lipid metabolic processGO:00442552080.036
amine metabolic processGO:0009308380.036
gland developmentGO:00487321550.035
cellular component assemblyGO:00226073600.035
response to estrogenGO:00436272320.035
positive regulation of transportGO:00510502450.035
tube developmentGO:0035295890.035
protein transportGO:00150311320.035
brain developmentGO:00074202470.034
response to woundingGO:00096112540.034
anterior posterior pattern specificationGO:000995210.033
negative regulation of nucleic acid templated transcriptionGO:19035071170.033
intracellular transportGO:00469071850.033
positive regulation of cell communicationGO:00106472710.033
regulation of neuron differentiationGO:00456642080.033
positive regulation of cell deathGO:00109421840.033
positive regulation of multicellular organismal processGO:00512403870.033
negative regulation of nitrogen compound metabolic processGO:00511721610.033
neuron differentiationGO:00301823680.032
regulation of protein modification processGO:00313991940.032
positive regulation of rna metabolic processGO:00512542030.032
cellular response to hormone stimulusGO:00328702470.032
cell cell signalingGO:00072673350.031
positive regulation of protein metabolic processGO:00512471780.031
positive regulation of protein modification processGO:00314011420.031
regulation of locomotionGO:00400121480.031
positive regulation of intracellular signal transductionGO:19025331380.030
response to mechanical stimulusGO:00096121340.030
regulation of cell morphogenesisGO:0022604770.030
response to hydrogen peroxideGO:0042542890.030
negative regulation of response to stimulusGO:00485851550.030
head developmentGO:00603222470.030
peptidyl tyrosine phosphorylationGO:0018108720.030
glycosyl compound metabolic processGO:19016571820.029
organic substance catabolic processGO:19015753160.029
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.029
negative regulation of cell proliferationGO:00082851190.029
nucleotide metabolic processGO:00091172790.029
positive regulation of transcription dna templatedGO:00458931970.029
inflammatory responseGO:00069541500.029
regulation of neuron projection developmentGO:00109751610.029
proteolysisGO:00065081750.029
positive regulation of cellular amino acid metabolic processGO:004576410.029
positive regulation of nucleic acid templated transcriptionGO:19035081970.028
small molecule biosynthetic processGO:00442831240.028
regulation of protein phosphorylationGO:00019321830.028
regulation of cell projection organizationGO:00313441750.028
negative regulation of developmental processGO:00510931250.028
positive regulation of phosphorylationGO:00423271770.028
positive regulation of signal transductionGO:00099671750.028
positive regulation of cell differentiationGO:00455972170.028
synaptic transmissionGO:00072682350.028
response to nutrient levelsGO:00316673700.028
cellular response to stressGO:00335542690.028
small gtpase mediated signal transductionGO:0007264360.028
response to oxygen levelsGO:00704822650.028
neuron projection developmentGO:00311752730.028
single organism catabolic processGO:00447122830.027
cardiovascular system developmentGO:00723581340.027
ras protein signal transductionGO:0007265290.027
cellular response to organic cyclic compoundGO:00714072020.027
cation transmembrane transportGO:00986552630.027
response to glucoseGO:00097491360.027
regulation of cellular localizationGO:00603412630.027
hepaticobiliary system developmentGO:0061008900.027
nucleoside phosphate metabolic processGO:00067532830.027
ion transmembrane transportGO:00342203650.027
g protein coupled receptor signaling pathwayGO:00071862420.027
metal ion transportGO:00300012890.027
negative regulation of cellular metabolic processGO:00313242810.026
liver developmentGO:0001889900.026
peptidyl tyrosine modificationGO:0018212720.026
lipid metabolic processGO:00066292830.026
positive regulation of apoptotic processGO:00430651540.026
tissue developmentGO:00098882520.026
nucleobase containing small molecule metabolic processGO:00550863160.026
regulation of nervous system developmentGO:00519602640.026
positive regulation of secretion by cellGO:19035321280.025
regulation of protein kinase activityGO:00458591050.025
cellular response to nitrogen compoundGO:19016992100.025
multi organism reproductive processGO:00447032620.025
response to hypoxiaGO:00016662310.025
intracellular protein transportGO:0006886790.025
mapk cascadeGO:00001651400.025
endocytosisGO:0006897840.024
purine ribonucleotide metabolic processGO:00091502270.024
regulation of neurogenesisGO:00507672470.024
positive regulation of cellular component organizationGO:00511302000.024
female pregnancyGO:00075651220.024
positive regulation of transferase activityGO:0051347810.024
cellular carbohydrate metabolic processGO:0044262720.024
positive regulation of protein phosphorylationGO:00019341350.024
epithelium developmentGO:0060429960.023
negative regulation of cellular biosynthetic processGO:00313271610.023
response to oxidative stressGO:00069791860.023
reproductionGO:00000032450.023
cellular catabolic processGO:00442482950.023
positive regulation of kinase activityGO:0033674770.023
transmembrane transportGO:00550854120.023
multicellular organism reproductionGO:00325042330.023
response to peptide hormoneGO:00434342780.022
protein oligomerizationGO:00512591910.022
positive regulation of cell proliferationGO:00082842490.022
cell cycleGO:00070491010.022
positive regulation of protein kinase activityGO:0045860730.022
positive regulation of programmed cell deathGO:00430681570.022
sulfur compound metabolic processGO:0006790700.022
oxidation reduction processGO:00551143040.022
cellular response to organonitrogen compoundGO:00714171970.022
multicellular organismal reproductive processGO:00486092330.022
positive regulation of locomotionGO:00400171020.022
positive regulation of gene expressionGO:00106282440.022
reproductive structure developmentGO:00486081280.022
cell type specific apoptotic processGO:00972851340.021
response to extracellular stimulusGO:00099913800.021
positive regulation of catalytic activityGO:00430851840.021
single organism cellular localizationGO:19025801020.021
positive regulation of cell motilityGO:2000147970.021
regulation of secretion by cellGO:19035302080.021
positive regulation of cellular amine metabolic processGO:003324030.021
response to vitaminGO:00332731310.021
secretion by cellGO:00329402480.021
single organism nuclear importGO:1902593350.020
response to ketoneGO:19016541820.020
ribonucleoside metabolic processGO:00091191740.020
anatomical structure formation involved in morphogenesisGO:0048646830.020
peptidyl amino acid modificationGO:00181931260.020
kidney developmentGO:0001822670.020
cellular macromolecule localizationGO:00707271220.020
response to cytokineGO:00340972150.020
cell adhesionGO:00071551100.020
purine nucleoside metabolic processGO:00422781690.020
protein targetingGO:0006605610.020
inorganic ion transmembrane transportGO:00986602290.019
inorganic cation transmembrane transportGO:00986622020.019
regulation of secretionGO:00510462240.019
regulation of hydrolase activityGO:00513361430.019
urogenital system developmentGO:0001655780.019
carbohydrate derivative biosynthetic processGO:19011371240.019
response to lipopolysaccharideGO:00324961910.019
response to purine containing compoundGO:00140741260.019
positive regulation of developmental processGO:00510942830.019
macromolecule localizationGO:00330362520.019
wound healingGO:00420601220.019
response to decreased oxygen levelsGO:00362932370.018
cell projection organizationGO:00300303020.018
neuron developmentGO:00486662860.018
organonitrogen compound catabolic processGO:19015651790.018
negative regulation of cellular component organizationGO:0051129830.018
rhythmic processGO:00485111560.018
positive regulation of cellular component movementGO:00512721020.017
nucleocytoplasmic transportGO:0006913480.017
circulatory system processGO:00030131830.017
maintenance of locationGO:0051235170.017
ribonucleotide metabolic processGO:00092592310.017
regulation of body fluid levelsGO:0050878900.017
ion homeostasisGO:00508012120.017
defense responseGO:00069521940.017
nuclear transportGO:0051169490.017
regulation of mapk cascadeGO:00434081160.017
negative regulation of cell differentiationGO:0045596990.017
growthGO:00400071650.017
response to organophosphorusGO:00466831020.017
blood vessel developmentGO:0001568690.017
positive regulation of cell developmentGO:00107201760.017
organophosphate biosynthetic processGO:00904071430.017
cation transportGO:00068123820.017
homeostatic processGO:00425923310.017
axis specificationGO:000979840.017
regulation of growthGO:00400081050.016
regulation of canonical wnt signaling pathwayGO:006082840.016
agingGO:00075682410.016
positive regulation of nervous system developmentGO:00519621780.016
renal system developmentGO:0072001670.016
acid secretionGO:0046717480.016
ribonucleotide catabolic processGO:00092611360.016
regulation of synaptic transmissionGO:00508041410.016
ribose phosphate metabolic processGO:00196932350.016
response to metal ionGO:00100382530.016
nitrogen compound transportGO:00717052290.016
cell morphogenesis involved in differentiationGO:00009041190.016
heart morphogenesisGO:000300730.016
protein import into nucleusGO:0006606350.016
single organism organelle organizationGO:19025891800.016
response to peptideGO:19016522920.016
response to insulinGO:00328681330.016
forebrain developmentGO:0030900980.016
cell morphogenesisGO:00009021420.016
divalent metal ion transportGO:00708381320.016
negative regulation of protein metabolic processGO:00512481140.016
blood circulationGO:00080151830.016
positive regulation of neurogenesisGO:00507691650.016
regulation of purine nucleotide catabolic processGO:0033121650.016
organic hydroxy compound metabolic processGO:19016151150.016
negative regulation of cell developmentGO:0010721820.015
cellular protein localizationGO:00346131220.015
cellular response to peptideGO:19016531330.015
cellular component morphogenesisGO:00329891550.015
cell growthGO:00160491040.015
positive regulation of secretionGO:00510471400.015
cellular calcium ion homeostasisGO:00068741600.015
regulation of gluconeogenesisGO:000611140.015
response to ethanolGO:00454711620.015
protein homooligomerizationGO:0051260910.015
cytoplasmic transportGO:00164821150.015
purine containing compound metabolic processGO:00725212530.015
jak stat cascadeGO:0007259260.015
protein localization to organelleGO:0033365570.015
regulation of cellular catabolic processGO:00313291010.015
cellular nitrogen compound catabolic processGO:00442701630.015
negative regulation of cell deathGO:00605482290.015
protein heterooligomerizationGO:0051291890.015
positive regulation of cell projection organizationGO:00313461110.015
nucleoside catabolic processGO:00091641260.015
protein processingGO:0016485680.014
digestive system developmentGO:0055123410.014
regulation of system processGO:00440572080.014
ribonucleoside catabolic processGO:00424541260.014
muscle system processGO:00030121150.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
biological adhesionGO:00226101100.014
regulation of vesicle mediated transportGO:0060627810.014
chemical homeostasisGO:00488782920.014
eye morphogenesisGO:004859240.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
regulation of catabolic processGO:00098941130.014
regulation of translationGO:0006417270.014
regulation of stem cell differentiationGO:200073620.014
cell activationGO:0001775970.014
nucleoside metabolic processGO:00091161790.014
response to nutrientGO:00075842480.014
cellular chemical homeostasisGO:00550822470.014
regulation of cell cycleGO:0051726730.014
gastrulationGO:000736920.014
regenerationGO:00310991630.014
positive regulation of cellular catabolic processGO:0031331710.014
negative regulation of osteoblast differentiationGO:004566820.014
positive regulation of cell migrationGO:0030335960.014
purine nucleotide metabolic processGO:00061632290.013
embryonic pattern specificationGO:000988010.013
positive regulation of mapk cascadeGO:0043410920.013
regulation of establishment of protein localizationGO:0070201690.013
nuclear importGO:0051170350.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
lipid storageGO:001991510.013
bmp signaling pathwayGO:003050940.013
negative regulation of transportGO:00510511360.013
purine nucleoside catabolic processGO:00061521240.013
behaviorGO:00076102050.013
cardiac ventricle developmentGO:000323110.013
negative regulation of cellular protein metabolic processGO:00322691060.013
neuron fate commitmentGO:004866340.013
cell fate determinationGO:000170920.013
cytokine biosynthetic processGO:004208930.013
regulation of cellular component biogenesisGO:0044087860.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
response to other organismGO:00517072200.013
fertilizationGO:000956630.013
purine ribonucleoside metabolic processGO:00461281680.013
nucleoside triphosphate catabolic processGO:00091431230.013
activation of protein kinase activityGO:0032147470.013
nucleoside phosphate biosynthetic processGO:19012931020.013
gtp catabolic processGO:0006184710.013
negative regulation of rna biosynthetic processGO:19026791180.013
regulation of ras protein signal transductionGO:0046578450.012
calcium ion transportGO:00068161310.012
muscle cell proliferationGO:0033002840.012
purine ribonucleotide biosynthetic processGO:0009152810.012
lipid localizationGO:0010876620.012
negative regulation of protein import into nucleus translocationGO:003315910.012
signal transduction by phosphorylationGO:00230141440.012
positive regulation of nucleotide metabolic processGO:0045981910.012
organophosphate catabolic processGO:00464341480.012
lipid biosynthetic processGO:00086101280.012
negative regulation of neurogenesisGO:0050768780.012
nucleotide biosynthetic processGO:0009165980.012
skeletal system developmentGO:0001501410.012
cellular homeostasisGO:00197252520.012
positive regulation of neuron differentiationGO:00456661260.012
negative regulation of cell communicationGO:00106481580.012
cellular response to drugGO:0035690300.012
cellular response to acid chemicalGO:0071229750.012
action potentialGO:0001508540.012
negative regulation of signalingGO:00230571570.012
protein targeting to nucleusGO:0044744350.012
protein maturationGO:0051604680.012
inner medullary collecting duct developmentGO:007206110.012
hormone secretionGO:00468791150.012
digestive tract developmentGO:0048565390.012
cellular response to reactive oxygen speciesGO:0034614550.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
monocarboxylic acid metabolic processGO:00327871520.011
circadian rhythmGO:0007623880.011
organic cyclic compound catabolic processGO:19013611750.011
regulation of response to woundingGO:1903034690.011
telencephalon developmentGO:0021537620.011
protein importGO:0017038370.011
chromosome organizationGO:0051276360.011
purine ribonucleoside catabolic processGO:00461301240.011
cytokine productionGO:0001816610.011
nucleotide catabolic processGO:00091661390.011
guanosine containing compound catabolic processGO:1901069710.011
regulation of vasculature developmentGO:1901342440.011
respiratory system developmentGO:0060541450.011
calcium ion homeostasisGO:00550741620.011
negative regulation of molecular functionGO:00440921330.011
activation of cysteine type endopeptidase activityGO:009720240.011
chromosome segregationGO:000705920.011
regulation of hormone levelsGO:00108171870.011
positive regulation of nucleoside metabolic processGO:0045979550.011
organic acid biosynthetic processGO:0016053830.011
neuronal action potentialGO:0019228350.011
artery developmentGO:006084030.011
regulation of protein import into nucleusGO:0042306240.011
positive regulation of hormone secretionGO:0046887650.011
antigen receptor mediated signaling pathwayGO:005085110.011
organonitrogen compound biosynthetic processGO:19015661670.011
rho protein signal transductionGO:0007266110.011
negative regulation of apoptotic processGO:00430661810.011
response to molecule of bacterial originGO:00022371940.011
nucleoside triphosphate metabolic processGO:00091411440.011
purine nucleotide catabolic processGO:00061951360.011
organ regenerationGO:00311001010.011
divalent inorganic cation transportGO:00725111340.011
purine nucleotide biosynthetic processGO:0006164830.011
regulation of protein transportGO:0051223680.010
signal releaseGO:00230611450.010
regulation of nucleocytoplasmic transportGO:0046822280.010
response to temperature stimulusGO:0009266940.010
positive regulation of endothelial cell migrationGO:001059540.010
mechanoreceptor differentiationGO:004249020.010
negative regulation of programmed cell deathGO:00430691830.010
cellular response to external stimulusGO:00714961180.010
regulation of intracellular transportGO:0032386650.010
multicellular organism growthGO:003526410.010
regulation of membrane potentialGO:00423911100.010
gliogenesisGO:0042063930.010
translationGO:0006412350.010
regulation of neuron deathGO:19012141150.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
metal ion homeostasisGO:00550651860.010
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.010
regulation of immunoglobulin productionGO:000263740.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
regulation of carbohydrate metabolic processGO:0006109410.010
regulation of blood vessel endothelial cell migrationGO:004353540.010
cation homeostasisGO:00550801950.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
regulation of cytokine biosynthetic processGO:004203530.010
regulation of activation of janus kinase activityGO:001053310.010
lung developmentGO:0030324430.010
negative regulation of cell cycle phase transitionGO:190198840.010
response to campGO:0051591910.010
establishment of protein localization to organelleGO:0072594440.010
glucose metabolic processGO:0006006520.010
regulation of protein localizationGO:0032880810.010

Eef2k disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
cardiovascular system diseaseDOID:128700.012
central nervous system diseaseDOID:33100.012
disease of cellular proliferationDOID:1456600.011
musculoskeletal system diseaseDOID:1700.011