Rattus norvegicus

34 known processes

Prnp

prion protein

(Aliases: Prn,PrP)

Prnp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of multicellular organismal processGO:00512412030.198
histamine secretion involved in inflammatory responseGO:000244130.188
nitrogen compound transportGO:00717052290.176
secretionGO:00469033070.157
regulation of cellular component organizationGO:00511283680.128
cation transportGO:00068123820.125
response to metal ionGO:00100382530.120
positive regulation of signalingGO:00230562700.119
catabolic processGO:00090563510.116
response to peptideGO:19016522920.106
secretion by cellGO:00329402480.105
regulation of transcription dna templatedGO:00063553740.105
regulation of hormone levelsGO:00108171870.097
single organism cellular localizationGO:19025801020.097
regulation of phosphorus metabolic processGO:00511743490.092
vesicle mediated transportGO:00161921810.090
ion transmembrane transportGO:00342203650.090
cellular macromolecule localizationGO:00707271220.088
metal ion transportGO:00300012890.081
response to inorganic substanceGO:00100353770.081
carbohydrate derivative metabolic processGO:19011353460.081
protein complex assemblyGO:00064612630.079
regulation of cellular localizationGO:00603412630.077
nucleic acid templated transcriptionGO:00976593790.075
ras protein signal transductionGO:0007265290.072
single organism intracellular transportGO:19025821660.070
macromolecule localizationGO:00330362520.066
negative regulation of gene expressionGO:00106291990.063
positive regulation of nitrogen compound metabolic processGO:00511733340.062
positive regulation of signal transductionGO:00099671750.061
negative regulation of nervous system developmentGO:0051961790.061
inorganic ion transmembrane transportGO:00986602290.061
protein phosphorylationGO:00064683450.060
cell projection organizationGO:00300303020.060
cellular component biogenesisGO:00440853680.059
intracellular transportGO:00469071850.058
regulation of programmed cell deathGO:00430673410.058
positive regulation of catalytic activityGO:00430851840.056
regulation of molecular functionGO:00650093980.056
regulation of ion transportGO:00432692450.056
positive regulation of phosphate metabolic processGO:00459372620.056
negative regulation of developmental processGO:00510931250.056
response to campGO:0051591910.055
reproductive processGO:00224143720.054
peptide metabolic processGO:0006518320.053
establishment of protein localizationGO:00451841410.053
inorganic cation transmembrane transportGO:00986622020.052
negative regulation of neurogenesisGO:0050768780.052
protein complex subunit organizationGO:00718223020.052
positive regulation of protein phosphorylationGO:00019341350.050
negative regulation of cell developmentGO:0010721820.049
neuron differentiationGO:00301823680.048
regulation of nucleic acid templated transcriptionGO:19035063800.048
positive regulation of phosphorus metabolic processGO:00105622620.047
positive regulation of cell communicationGO:00106472710.047
anion transportGO:00068201780.046
carbohydrate metabolic processGO:00059751300.046
cellular response to hormone stimulusGO:00328702470.045
anatomical structure morphogenesisGO:00096532980.045
cellular response to insulin stimulusGO:0032869810.045
carboxylic acid metabolic processGO:00197522890.045
regulation of nervous system developmentGO:00519602640.044
positive regulation of response to stimulusGO:00485842850.044
cellular protein localizationGO:00346131220.043
cardiac chamber developmentGO:000320510.043
regulation of rna biosynthetic processGO:20011413810.042
response to calcium ionGO:0051592590.042
head developmentGO:00603222470.042
cellular amide metabolic processGO:0043603440.042
regulation of signal transductionGO:00099663180.041
positive regulation of biosynthetic processGO:00098913190.041
regulation of multicellular organismal developmentGO:20000263760.041
response to insulinGO:00328681330.041
cellular response to nitrogen compoundGO:19016992100.040
response to amineGO:0014075460.040
positive regulation of phosphorylationGO:00423271770.040
regulation of catalytic activityGO:00507903040.040
macromolecular complex assemblyGO:00650032730.040
neuron projection developmentGO:00311752730.040
negative regulation of cell proliferationGO:00082851190.040
oxoacid metabolic processGO:00434362900.039
protein localizationGO:00081041910.039
multi organism reproductive processGO:00447032620.039
neurological system processGO:00508772190.038
macromolecular complex subunit organizationGO:00439333390.038
divalent inorganic cation transportGO:00725111340.038
positive regulation of multicellular organismal processGO:00512403870.037
response to glucocorticoidGO:00513842230.037
response to peptide hormoneGO:00434342780.037
regulation of hydrolase activityGO:00513361430.036
defense responseGO:00069521940.036
response to carbohydrateGO:00097431830.036
negative regulation of nucleobase containing compound metabolic processGO:00459341530.036
divalent metal ion transportGO:00708381320.035
localization of cellGO:00516742020.035
transcription dna templatedGO:00063513770.034
regulation of cell differentiationGO:00455953200.034
protein oligomerizationGO:00512591910.034
regulation of neurogenesisGO:00507672470.033
cellular amine metabolic processGO:0044106380.033
response to nutrient levelsGO:00316673700.033
intracellular signal transductionGO:00355563140.032
cellular response to peptide hormone stimulusGO:00713751200.032
rna biosynthetic processGO:00327743800.032
regulation of phosphate metabolic processGO:00192203490.031
homeostatic processGO:00425923310.031
cellular response to peptideGO:19016531330.031
cellular response to stressGO:00335542690.031
positive regulation of programmed cell deathGO:00430681570.031
carbohydrate derivative catabolic processGO:19011361470.031
organic substance catabolic processGO:19015753160.031
response to molecule of bacterial originGO:00022371940.031
regulation of cell proliferationGO:00421273590.031
protein complex biogenesisGO:00702712630.030
transmembrane transportGO:00550854120.030
cellular component assemblyGO:00226073600.030
regulation of protein modification processGO:00313991940.030
transcription from rna polymerase ii promoterGO:00063662520.030
positive regulation of cellular biosynthetic processGO:00313282950.030
positive regulation of gene expressionGO:00106282440.029
positive regulation of transcription dna templatedGO:00458931970.029
protein heterooligomerizationGO:0051291890.029
protein transportGO:00150311320.029
negative regulation of cellular metabolic processGO:00313242810.029
intracellular protein transportGO:0006886790.029
cellular response to oxygen containing compoundGO:19017013860.029
positive regulation of transportGO:00510502450.028
multicellular organismal reproductive processGO:00486092330.028
protein processingGO:0016485680.028
cellular component movementGO:00069282480.028
positive regulation of macromolecule biosynthetic processGO:00105572470.028
cellular response to organonitrogen compoundGO:00714171970.028
regulation of neuron differentiationGO:00456642080.028
chemical homeostasisGO:00488782920.027
positive regulation of secretionGO:00510471400.027
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
establishment of protein localization to organelleGO:0072594440.027
monocarboxylic acid transportGO:0015718520.027
regulation of high voltage gated calcium channel activityGO:190184130.027
organophosphate catabolic processGO:00464341480.027
positive regulation of developmental processGO:00510942830.027
negative regulation of transportGO:00510511360.027
regulation of calcium ion transmembrane transporter activityGO:1901019170.026
protein targetingGO:0006605610.026
positive regulation of neurogenesisGO:00507691650.026
regulation of cell developmentGO:00602842630.026
cellular chemical homeostasisGO:00550822470.026
organonitrogen compound catabolic processGO:19015651790.026
anion transmembrane transportGO:0098656770.026
cellular catabolic processGO:00442482950.026
positive regulation of protein metabolic processGO:00512471780.025
regulation of cellular protein metabolic processGO:00322682670.025
signal releaseGO:00230611450.025
cell motilityGO:00488702020.025
response to corticosteroidGO:00319602350.025
multicellular organism reproductionGO:00325042330.025
positive regulation of cell differentiationGO:00455972170.025
positive regulation of cell developmentGO:00107201760.024
neuron developmentGO:00486662860.024
regulation of ion transmembrane transportGO:00347651210.024
cellular homeostasisGO:00197252520.024
positive regulation of nervous system developmentGO:00519621780.024
cellular ketone metabolic processGO:0042180510.024
response to ethanolGO:00454711620.024
positive regulation of neuron differentiationGO:00456661260.024
regulation of protein metabolic processGO:00512462890.023
organelle organizationGO:00069962660.023
regulation of metal ion transportGO:00109591180.023
calcium ion transportGO:00068161310.023
cell cell signalingGO:00072673350.023
small gtpase mediated signal transductionGO:0007264360.023
cardiac ventricle developmentGO:000323110.023
central nervous system developmentGO:00074173110.023
negative regulation of protein metabolic processGO:00512481140.023
cellular amino acid metabolic processGO:00065201070.023
mitochondrion organizationGO:0007005350.023
organic anion transportGO:00157111320.023
regulation of secretionGO:00510462240.023
carbohydrate derivative biosynthetic processGO:19011371240.022
regulation of rna metabolic processGO:00512523910.022
positive regulation of cellular protein metabolic processGO:00322701670.022
negative regulation of cell differentiationGO:0045596990.022
response to growth factorGO:00708481890.022
organic acid metabolic processGO:00060822920.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
hormone transportGO:00099141210.022
apoptotic processGO:00069153810.022
ion homeostasisGO:00508012120.022
regulation of apoptotic processGO:00429813350.022
single organism catabolic processGO:00447122830.022
rna metabolic processGO:00160704060.021
calcium ion transmembrane transportGO:0070588700.021
regulation of calcium ion transportGO:0051924770.021
response to extracellular stimulusGO:00099913800.021
cellular response to endogenous stimulusGO:00714953770.021
protein localization to organelleGO:0033365570.021
positive regulation of apoptotic processGO:00430651540.021
response to woundingGO:00096112540.021
negative regulation of protein transportGO:0051224170.021
regulation of cellular amine metabolic processGO:003323880.021
regenerationGO:00310991630.021
negative regulation of metabolic processGO:00098923310.020
positive regulation of molecular functionGO:00440932300.020
carboxylic acid transportGO:00469421150.020
negative regulation of macromolecule metabolic processGO:00106052600.020
positive regulation of cell projection organizationGO:00313461110.020
cation transmembrane transportGO:00986552630.020
positive regulation of rna metabolic processGO:00512542030.020
inflammatory responseGO:00069541500.020
regulation of calcium ion transmembrane transportGO:1903169180.019
organic hydroxy compound transportGO:0015850770.019
response to hypoxiaGO:00016662310.019
reproductionGO:00000032450.019
organophosphate metabolic processGO:00196373700.019
regulation of synaptic plasticityGO:0048167700.019
cellular response to organic cyclic compoundGO:00714072020.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
purine ribonucleotide catabolic processGO:00091541360.019
single organism biosynthetic processGO:00447113420.019
regulation of cell migrationGO:00303341280.018
protein maturationGO:0051604680.018
centrosome organizationGO:005129710.018
regulation of ryanodine sensitive calcium release channel activityGO:006031450.018
hormone metabolic processGO:0042445690.018
response to cytokineGO:00340972150.018
cation homeostasisGO:00550801950.018
purine containing compound metabolic processGO:00725212530.018
lipid metabolic processGO:00066292830.018
female pregnancyGO:00075651220.018
positive regulation of cellular component organizationGO:00511302000.018
negative regulation of transcription dna templatedGO:00458921160.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
mast cell activationGO:0045576150.018
regulation of cell projection organizationGO:00313441750.018
cell adhesionGO:00071551100.018
hormone secretionGO:00468791150.017
regulation of purine nucleotide metabolic processGO:19005421150.017
response to organophosphorusGO:00466831020.017
single organism reproductive processGO:00447022970.017
regulation of neuron projection developmentGO:00109751610.017
positive regulation of protein modification processGO:00314011420.017
reproductive system developmentGO:00614581280.017
regulation of ion transmembrane transporter activityGO:0032412480.017
single organism nuclear importGO:1902593350.017
negative regulation of rna biosynthetic processGO:19026791180.017
proteolysisGO:00065081750.017
single organism carbohydrate metabolic processGO:00447231180.017
regulation of locomotionGO:00400121480.017
ribose phosphate metabolic processGO:00196932350.017
cellular response to growth factor stimulusGO:00713631620.017
amine metabolic processGO:0009308380.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
gland developmentGO:00487321550.016
regulation of protein transportGO:0051223680.016
negative regulation of biosynthetic processGO:00098901680.016
response to glucoseGO:00097491360.016
somatic stem cell divisionGO:004810320.016
positive regulation of secretion by cellGO:19035321280.016
regulation of transmembrane transportGO:00347621220.016
negative regulation of neuron differentiationGO:0045665620.016
response to hexoseGO:00097461440.016
regulation of cellular amino acid metabolic processGO:000652120.016
positive regulation of cell deathGO:00109421840.016
regulation of intracellular signal transductionGO:19025312180.016
negative regulation of molecular functionGO:00440921330.016
cell activationGO:0001775970.016
response to ketoneGO:19016541820.016
regulation of transporter activityGO:0032409500.015
nuclear transportGO:0051169490.015
positive regulation of cellular amine metabolic processGO:003324030.015
synaptic transmissionGO:00072682350.015
negative regulation of cellular protein metabolic processGO:00322691060.015
response to bacteriumGO:00096172000.015
immune responseGO:00069551040.015
developmental process involved in reproductionGO:00030061590.015
exocytosisGO:0006887600.015
response to purine containing compoundGO:00140741260.015
gliogenesisGO:0042063930.015
locomotionGO:00400112370.015
regulation of nitric oxide synthase activityGO:005099980.015
nucleoside phosphate metabolic processGO:00067532830.015
regulation of smoothened signaling pathwayGO:000858920.014
multicellular organism growthGO:003526410.014
histamine secretion by mast cellGO:000255330.014
nucleocytoplasmic transportGO:0006913480.014
reproductive structure developmentGO:00486081280.014
protein targeting to nucleusGO:0044744350.014
brain developmentGO:00074202470.014
positive regulation of rna biosynthetic processGO:19026801970.014
positive regulation of hydrolase activityGO:0051345860.014
ribonucleoside catabolic processGO:00424541260.014
regulation of establishment of protein localizationGO:0070201690.014
tissue developmentGO:00098882520.014
protein localization to nucleusGO:0034504390.014
glial cell differentiationGO:0010001650.014
camp biosynthetic processGO:0006171470.014
multi multicellular organism processGO:00447061380.014
regulation of system processGO:00440572080.014
regulation of cell motilityGO:20001451310.014
histamine production involved in inflammatory responseGO:000234930.014
aromatic compound catabolic processGO:00194391680.014
purine containing compound catabolic processGO:00725231380.013
protein import into nucleusGO:0006606350.013
regulation of cyclic nucleotide metabolic processGO:0030799510.013
organic hydroxy compound metabolic processGO:19016151150.013
regulation of anatomical structure sizeGO:00900661350.013
chemosensory behaviorGO:000763520.013
cellular cation homeostasisGO:00300031800.013
multicellular organismal signalingGO:0035637440.013
response to acid chemicalGO:00011012220.013
action potentialGO:0001508540.013
divalent inorganic cation homeostasisGO:00725071650.013
mesoderm developmentGO:000749820.013
purine nucleotide metabolic processGO:00061632290.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
cardiovascular system developmentGO:00723581340.013
microtubule organizing center organizationGO:003102310.013
axis specificationGO:000979840.013
leukocyte activationGO:0045321760.013
regulation of voltage gated calcium channel activityGO:190138560.013
protein homooligomerizationGO:0051260910.013
purine nucleoside catabolic processGO:00061521240.013
behaviorGO:00076102050.013
response to oxygen levelsGO:00704822650.013
response to biotic stimulusGO:00096072260.013
response to amphetamineGO:0001975250.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
nucleobase containing small molecule metabolic processGO:00550863160.013
ribonucleotide catabolic processGO:00092611360.013
circulatory system developmentGO:00723591340.013
sexual reproductionGO:00199531480.013
cell cycleGO:00070491010.013
negative regulation of macromolecule biosynthetic processGO:00105581480.012
positive regulation of hormone secretionGO:0046887650.012
response to decreased oxygen levelsGO:00362932370.012
ribonucleoside metabolic processGO:00091191740.012
purine ribonucleoside catabolic processGO:00461301240.012
regulation of cellular component movementGO:00512701500.012
nucleotide metabolic processGO:00091172790.012
response to reactive oxygen speciesGO:00003021200.012
glucose homeostasisGO:0042593750.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
centrosome cycleGO:000709810.012
protein localization to membraneGO:0072657360.012
response to monosaccharideGO:00342841590.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
protein importGO:0017038370.012
regulation of catabolic processGO:00098941130.012
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.012
cytoplasmic transportGO:00164821150.012
cell activation involved in immune responseGO:0002263160.012
salivary gland developmentGO:000743130.012
negative regulation of neuron projection developmentGO:0010977460.012
neuron projection regenerationGO:0031102350.012
gamete generationGO:00072761240.011
embryonic pattern specificationGO:000988010.011
protein targeting to plasma membraneGO:007266140.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
organic acid transportGO:00158491160.011
regulation of secretion by cellGO:19035302080.011
positive regulation of protein kinase activityGO:0045860730.011
spindle organizationGO:000705120.011
regulation of cellular ketone metabolic processGO:0010565270.011
negative regulation of rna metabolic processGO:00512531230.011
monosaccharide metabolic processGO:0005996610.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
cell morphogenesisGO:00009021420.011
response to nutrientGO:00075842480.011
regulation of proteolysisGO:0030162660.011
odontogenesisGO:0042476320.011
positive regulation of cell proliferationGO:00082842490.011
response to axon injuryGO:0048678590.011
camp metabolic processGO:0046058630.011
regulation of anatomical structure morphogenesisGO:00226031410.011
regulation of nucleocytoplasmic transportGO:0046822280.011
regulation of long term neuronal synaptic plasticityGO:0048169150.011
regulation of ras protein signal transductionGO:0046578450.011
cellular response to carbohydrate stimulusGO:0071322720.011
circulatory system processGO:00030131830.011
response to other organismGO:00517072200.011
response to radiationGO:00093141370.011
regulation of protein phosphorylationGO:00019321830.011
negative regulation of secretionGO:0051048820.011
peptide hormone secretionGO:0030072840.011
embryo implantationGO:0007566150.011
cellular component morphogenesisGO:00329891550.011
regulation of monooxygenase activityGO:003276880.011
gtp metabolic processGO:0046039720.011
cellular response to glucose stimulusGO:0071333650.011
insulin secretionGO:0030073690.011
heterocycle catabolic processGO:00467001670.011
purine nucleotide catabolic processGO:00061951360.010
regulation of kinase activityGO:00435491170.010
regulation of transferase activityGO:00513381230.010
rho protein signal transductionGO:0007266110.010
guanosine containing compound metabolic processGO:1901068740.010
regulation of growthGO:00400081050.010
cellular response to cytokine stimulusGO:00713451270.010
cellular nitrogen compound catabolic processGO:00442701630.010
response to alkaloidGO:00432791320.010
peptide catabolic processGO:004317150.010
regulation of hormone secretionGO:00468831060.010
regulation of response to woundingGO:1903034690.010
regulation of phosphorylationGO:00423252480.010
signal transduction by phosphorylationGO:00230141440.010

Prnp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.026
disease of anatomical entityDOID:700.026
eye and adnexa diseaseDOID:149200.022
sensory system diseaseDOID:005015500.022
eye diseaseDOID:561400.022
disease of metabolismDOID:001466700.014
acquired metabolic diseaseDOID:006015800.010
blood protein diseaseDOID:62000.010
immune system diseaseDOID:291400.010
hematopoietic system diseaseDOID:7400.010