IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Ppcs

phosphopantothenoylcysteine synthetase

(Aliases: RGD1311399,MGC116383)

Ensembl: ENSRNOG00000008572
Entrez: 298490
RGD: 1311399
UniProtKB: D4A6X7

Process Predictions
Disease Predictions

Ppcs biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
cofactor metabolic process	GO:0051186	95	0.032
single organism catabolic process	GO:0044712	283	0.031
protein complex biogenesis	GO:0070271	263	0.030
oxoacid metabolic process	GO:0043436	290	0.030
carboxylic acid metabolic process	GO:0019752	289	0.027
catabolic process	GO:0009056	351	0.026
cellular ketone metabolic process	GO:0042180	51	0.025
protein complex assembly	GO:0006461	263	0.025
cellular component biogenesis	GO:0044085	368	0.023
organic acid metabolic process	GO:0006082	292	0.022
lipid metabolic process	GO:0006629	283	0.022
cellular catabolic process	GO:0044248	295	0.022
organophosphate metabolic process	GO:0019637	370	0.021
coenzyme metabolic process	GO:0006732	86	0.021
acyl coa metabolic process	GO:0006637	28	0.020
protein oligomerization	GO:0051259	191	0.020
nucleoside phosphate metabolic process	GO:0006753	283	0.020
response to oxygen levels	GO:0070482	265	0.020
regulation of molecular function	GO:0065009	398	0.019
positive regulation of multicellular organismal process	GO:0051240	387	0.019
single organism biosynthetic process	GO:0044711	342	0.019
monocarboxylic acid metabolic process	GO:0032787	152	0.019
response to hypoxia	GO:0001666	231	0.019
regulation of cellular ketone metabolic process	GO:0010565	27	0.018
cellular component assembly	GO:0022607	360	0.018
regulation of nervous system development	GO:0051960	264	0.018
cell projection organization	GO:0030030	302	0.018
cation transport	GO:0006812	382	0.018
cellular lipid metabolic process	GO:0044255	208	0.017
response to nutrient levels	GO:0031667	370	0.017
protein complex subunit organization	GO:0071822	302	0.017
organic substance catabolic process	GO:1901575	316	0.017
macromolecular complex assembly	GO:0065003	273	0.017
negative regulation of metabolic process	GO:0009892	331	0.017
response to inorganic substance	GO:0010035	377	0.017
carbohydrate derivative metabolic process	GO:1901135	346	0.017
cellular amine metabolic process	GO:0044106	38	0.017
organelle organization	GO:0006996	266	0.017
ion transmembrane transport	GO:0034220	365	0.016
response to extracellular stimulus	GO:0009991	380	0.016
response to decreased oxygen levels	GO:0036293	237	0.016
regulation of cellular amino acid metabolic process	GO:0006521	2	0.016
amine metabolic process	GO:0009308	38	0.016
oxidation reduction process	GO:0055114	304	0.015
neuron differentiation	GO:0030182	368	0.015
regulation of catalytic activity	GO:0050790	304	0.015
lipid biosynthetic process	GO:0008610	128	0.015
cofactor biosynthetic process	GO:0051188	28	0.015
homeostatic process	GO:0042592	331	0.015
central nervous system development	GO:0007417	311	0.015
programmed cell death	GO:0012501	392	0.015
positive regulation of cell proliferation	GO:0008284	249	0.015
reproductive process	GO:0022414	372	0.014
macromolecular complex subunit organization	GO:0043933	339	0.014
nucleoside metabolic process	GO:0009116	179	0.014
nucleobase containing small molecule metabolic process	GO:0055086	316	0.014
multicellular organismal reproductive process	GO:0048609	233	0.014
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
regulation of neurogenesis	GO:0050767	247	0.014
neuron development	GO:0048666	286	0.014
neuron projection development	GO:0031175	273	0.014
regulation of multicellular organismal development	GO:2000026	376	0.013
nucleotide metabolic process	GO:0009117	279	0.013
cellular response to oxygen containing compound	GO:1901701	386	0.013
brain development	GO:0007420	247	0.013
apoptotic process	GO:0006915	381	0.013
chemical homeostasis	GO:0048878	292	0.013
heart morphogenesis	GO:0003007	3	0.013
positive regulation of developmental process	GO:0051094	283	0.013
regulation of cellular component organization	GO:0051128	368	0.013
regulation of cell development	GO:0060284	263	0.013
action potential	GO:0001508	54	0.013
response to acid chemical	GO:0001101	222	0.013
purine containing compound metabolic process	GO:0072521	253	0.013
transmembrane transport	GO:0055085	412	0.013
positive regulation of molecular function	GO:0044093	230	0.013
single organism reproductive process	GO:0044702	297	0.012
cellular homeostasis	GO:0019725	252	0.012
multicellular organism reproduction	GO:0032504	233	0.012
regulation of cellular amine metabolic process	GO:0033238	8	0.012
reproduction	GO:0000003	245	0.012
cellular amino acid metabolic process	GO:0006520	107	0.012
response to nutrient	GO:0007584	248	0.012
single organism intracellular transport	GO:1902582	166	0.012
glycosyl compound metabolic process	GO:1901657	182	0.012
response to monosaccharide	GO:0034284	159	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.011
regulation of programmed cell death	GO:0043067	341	0.011
regulation of phosphorus metabolic process	GO:0051174	349	0.011
purine ribonucleotide metabolic process	GO:0009150	227	0.011
ribose phosphate metabolic process	GO:0019693	235	0.011
small molecule catabolic process	GO:0044282	59	0.011
response to carbohydrate	GO:0009743	183	0.011
secretion	GO:0046903	307	0.011
gastrulation	GO:0007369	2	0.011
metal ion transport	GO:0030001	289	0.011
sex differentiation	GO:0007548	113	0.011
regulation of cell projection organization	GO:0031344	175	0.011
embryonic pattern specification	GO:0009880	1	0.011
positive regulation of cell differentiation	GO:0045597	217	0.011
response to growth factor	GO:0070848	189	0.010
cellular response to stress	GO:0033554	269	0.010
regulation of cell differentiation	GO:0045595	320	0.010
negative regulation of cell communication	GO:0010648	158	0.010
multi organism reproductive process	GO:0044703	262	0.010
fatty acid metabolic process	GO:0006631	99	0.010
protein phosphorylation	GO:0006468	345	0.010
purine nucleotide metabolic process	GO:0006163	229	0.010
cellular chemical homeostasis	GO:0055082	247	0.010
response to molecule of bacterial origin	GO:0002237	194	0.010
carbohydrate derivative biosynthetic process	GO:1901137	124	0.010
positive regulation of cell development	GO:0010720	176	0.010
response to glucose	GO:0009749	136	0.010
sulfur compound metabolic process	GO:0006790	70	0.010
proteolysis	GO:0006508	175	0.010
positive regulation of nervous system development	GO:0051962	178	0.010
carbohydrate derivative catabolic process	GO:1901136	147	0.010
regulation of neuron projection development	GO:0010975	161	0.010

Ppcs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.017
disease of anatomical entity	DOID:7	0.017
disease of metabolism	DOID:0014667	0.014
sensory system disease	DOID:0050155	0.011
inherited metabolic disorder	DOID:655	0.011
musculoskeletal system disease	DOID:17	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network