Rattus norvegicus

0 known processes

Top3a

topoisomerase (DNA) III alpha

Top3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna metabolic processGO:00512523910.058
regulation of nucleic acid templated transcriptionGO:19035063800.058
positive regulation of nitrogen compound metabolic processGO:00511733340.057
regulation of phosphorus metabolic processGO:00511743490.052
regulation of rna biosynthetic processGO:20011413810.051
single organism biosynthetic processGO:00447113420.051
regulation of phosphate metabolic processGO:00192203490.051
tube developmentGO:0035295890.049
regulation of phosphorylationGO:00423252480.044
positive regulation of developmental processGO:00510942830.044
cellular response to stressGO:00335542690.043
Fly
regulation of signal transductionGO:00099663180.043
rna biosynthetic processGO:00327743800.042
cellular response to endogenous stimulusGO:00714953770.041
cellular response to hormone stimulusGO:00328702470.041
rna metabolic processGO:00160704060.040
nucleic acid templated transcriptionGO:00976593790.040
cellular component movementGO:00069282480.039
regulation of molecular functionGO:00650093980.039
organic acid metabolic processGO:00060822920.038
negative regulation of biosynthetic processGO:00098901680.038
cell projection organizationGO:00300303020.037
positive regulation of biosynthetic processGO:00098913190.037
positive regulation of phosphate metabolic processGO:00459372620.037
cell migrationGO:00164771970.036
cellular component biogenesisGO:00440853680.036
protein phosphorylationGO:00064683450.036
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
negative regulation of metabolic processGO:00098923310.035
regulation of cellular amino acid metabolic processGO:000652120.035
programmed cell deathGO:00125013920.035
regulation of transcription dna templatedGO:00063553740.035
cellular amino acid metabolic processGO:00065201070.034
negative regulation of macromolecule metabolic processGO:00106052600.034
positive regulation of cellular biosynthetic processGO:00313282950.034
intracellular signal transductionGO:00355563140.034
positive regulation of macromolecule biosynthetic processGO:00105572470.033
regulation of cellular amine metabolic processGO:003323880.033
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.033
positive regulation of rna biosynthetic processGO:19026801970.032
positive regulation of nucleic acid templated transcriptionGO:19035081970.032
regulation of neurogenesisGO:00507672470.032
apoptotic processGO:00069153810.032
macromolecule localizationGO:00330362520.031
single organism reproductive processGO:00447022970.031
regulation of cellular ketone metabolic processGO:0010565270.031
cellular component assemblyGO:00226073600.031
positive regulation of gene expressionGO:00106282440.030
cellular ketone metabolic processGO:0042180510.030
positive regulation of rna metabolic processGO:00512542030.029
anatomical structure morphogenesisGO:00096532980.029
negative regulation of nitrogen compound metabolic processGO:00511721610.029
carboxylic acid metabolic processGO:00197522890.029
response to carbohydrateGO:00097431830.029
negative regulation of cellular metabolic processGO:00313242810.028
positive regulation of molecular functionGO:00440932300.028
response to hypoxiaGO:00016662310.027
response to inorganic substanceGO:00100353770.026
cofactor metabolic processGO:0051186950.026
organophosphate metabolic processGO:00196373700.026
oxoacid metabolic processGO:00434362900.026
multi organism reproductive processGO:00447032620.025
regulation of cell developmentGO:00602842630.025
response to estrogenGO:00436272320.025
negative regulation of signalingGO:00230571570.025
regulation of cell differentiationGO:00455953200.024
positive regulation of multicellular organismal processGO:00512403870.024
regulation of programmed cell deathGO:00430673410.024
regulation of cell proliferationGO:00421273590.024
negative regulation of gene expressionGO:00106291990.024
regulation of cellular component movementGO:00512701500.024
amine metabolic processGO:0009308380.024
carbohydrate derivative metabolic processGO:19011353460.023
positive regulation of cell developmentGO:00107201760.023
cellular amine metabolic processGO:0044106380.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
cell cell signalingGO:00072673350.023
negative regulation of response to stimulusGO:00485851550.023
regulation of catalytic activityGO:00507903040.022
anterior posterior pattern specificationGO:000995210.022
response to nutrient levelsGO:00316673700.022
regulation of purine nucleotide metabolic processGO:19005421150.022
positive regulation of nervous system developmentGO:00519621780.022
positive regulation of neurogenesisGO:00507691650.022
positive regulation of cellular amine metabolic processGO:003324030.022
cellular response to oxygen containing compoundGO:19017013860.021
transcription dna templatedGO:00063513770.021
multicellular organism reproductionGO:00325042330.021
negative regulation of multicellular organismal processGO:00512412030.021
response to oxygen levelsGO:00704822650.021
positive regulation of phosphorus metabolic processGO:00105622620.021
macromolecular complex assemblyGO:00650032730.021
regulation of nervous system developmentGO:00519602640.021
regulation of intracellular signal transductionGO:19025312180.021
positive regulation of transcription dna templatedGO:00458931970.021
cell motilityGO:00488702020.020
response to insulinGO:00328681330.020
embryonic pattern specificationGO:000988010.020
central nervous system developmentGO:00074173110.020
reproductive processGO:00224143720.020
response to extracellular stimulusGO:00099913800.020
negative regulation of cell communicationGO:00106481580.020
response to decreased oxygen levelsGO:00362932370.019
neuron projection developmentGO:00311752730.019
multicellular organism growthGO:003526410.019
cell morphogenesis involved in differentiationGO:00009041190.019
ribose phosphate metabolic processGO:00196932350.019
cellular response to organonitrogen compoundGO:00714171970.019
nucleobase containing small molecule metabolic processGO:00550863160.019
nucleotide metabolic processGO:00091172790.019
localization of cellGO:00516742020.019
small gtpase mediated signal transductionGO:0007264360.019
developmental process involved in reproductionGO:00030061590.019
purine nucleotide metabolic processGO:00061632290.019
protein complex biogenesisGO:00702712630.019
neuron developmentGO:00486662860.018
negative regulation of rna metabolic processGO:00512531230.018
neuron differentiationGO:00301823680.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
positive regulation of cell proliferationGO:00082842490.018
nucleoside phosphate metabolic processGO:00067532830.018
positive regulation of phosphorylationGO:00423271770.018
axis specificationGO:000979840.018
regulation of protein modification processGO:00313991940.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
positive regulation of cell projection organizationGO:00313461110.018
negative regulation of molecular functionGO:00440921330.017
response to ethanolGO:00454711620.017
regulation of cell migrationGO:00303341280.017
regulation of peptide transportGO:0090087870.017
hepaticobiliary system developmentGO:0061008900.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
multicellular organismal reproductive processGO:00486092330.017
macromolecular complex subunit organizationGO:00439333390.017
transcription from rna polymerase ii promoterGO:00063662520.017
positive regulation of protein phosphorylationGO:00019341350.017
regulation of anatomical structure morphogenesisGO:00226031410.016
positive regulation of cellular component organizationGO:00511302000.016
response to glucocorticoidGO:00513842230.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
response to monosaccharideGO:00342841590.016
female pregnancyGO:00075651220.016
head developmentGO:00603222470.016
positive regulation of cell differentiationGO:00455972170.016
nucleoside metabolic processGO:00091161790.016
positive regulation of protein modification processGO:00314011420.016
locomotionGO:00400112370.016
positive regulation of cell deathGO:00109421840.016
glycosyl compound metabolic processGO:19016571820.016
response to estradiolGO:00323551640.016
cellular response to nitrogen compoundGO:19016992100.016
gastrulationGO:000736920.015
lipid metabolic processGO:00066292830.015
cellular response to reactive oxygen speciesGO:0034614550.015
response to metal ionGO:00100382530.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
ras protein signal transductionGO:0007265290.015
gland developmentGO:00487321550.015
regulation of cellular localizationGO:00603412630.015
homeostatic processGO:00425923310.015
response to hexoseGO:00097461440.015
sexual reproductionGO:00199531480.015
organonitrogen compound biosynthetic processGO:19015661670.015
negative regulation of protein metabolic processGO:00512481140.015
cation transportGO:00068123820.015
positive regulation of neuron projection developmentGO:0010976990.014
coenzyme metabolic processGO:0006732860.014
cellular lipid metabolic processGO:00442552080.014
regulation of protein phosphorylationGO:00019321830.014
reproductionGO:00000032450.014
peptidyl amino acid modificationGO:00181931260.014
positive regulation of apoptotic processGO:00430651540.014
response to glucoseGO:00097491360.014
brain developmentGO:00074202470.014
purine ribonucleotide catabolic processGO:00091541360.014
regulation of cellular protein metabolic processGO:00322682670.014
carbohydrate derivative biosynthetic processGO:19011371240.014
positive regulation of catalytic activityGO:00430851840.014
negative regulation of cellular protein metabolic processGO:00322691060.014
single organism intracellular transportGO:19025821660.014
purine ribonucleotide metabolic processGO:00091502270.014
reproductive structure developmentGO:00486081280.014
negative regulation of transcription dna templatedGO:00458921160.014
carbohydrate homeostasisGO:0033500750.014
regulation of locomotionGO:00400121480.014
response to peptideGO:19016522920.014
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
regulation of cell projection organizationGO:00313441750.014
response to woundingGO:00096112540.014
Fly
response to acid chemicalGO:00011012220.014
olfactory learningGO:000835510.013
response to growth factorGO:00708481890.013
negative regulation of catalytic activityGO:00430861030.013
intracellular transportGO:00469071850.013
response to lipopolysaccharideGO:00324961910.013
cellular response to insulin stimulusGO:0032869810.013
regulation of protein metabolic processGO:00512462890.013
regulation of kinase activityGO:00435491170.013
reactive oxygen species metabolic processGO:0072593370.013
positive regulation of response to stimulusGO:00485842850.013
purine ribonucleoside metabolic processGO:00461281680.013
regulation of nucleotide metabolic processGO:00061401170.013
multi multicellular organism processGO:00447061380.013
response to other organismGO:00517072200.013
response to mechanical stimulusGO:00096121340.013
response to corticosteroidGO:00319602350.013
regulation of cell motilityGO:20001451310.013
negative regulation of signal transductionGO:0009968830.013
cellular component morphogenesisGO:00329891550.012
cellular response to oxidative stressGO:0034599760.012
negative regulation of developmental processGO:00510931250.012
response to peptide hormoneGO:00434342780.012
lipid storageGO:001991510.012
neurological system processGO:00508772190.012
positive regulation of signalingGO:00230562700.012
purine containing compound metabolic processGO:00725212530.012
cell cycleGO:00070491010.012
response to oxidative stressGO:00069791860.012
regulation of cellular component organizationGO:00511283680.012
neuron projection morphogenesisGO:00488121220.012
positive regulation of neuron differentiationGO:00456661260.012
epithelium developmentGO:0060429960.012
organ regenerationGO:00311001010.012
circadian rhythmGO:0007623880.012
amide transportGO:00428861050.012
regulation of peptide secretionGO:0002791820.012
positive regulation of protein metabolic processGO:00512471780.012
negative regulation of cellular biosynthetic processGO:00313271610.012
gamete generationGO:00072761240.012
neuron deathGO:00709971270.012
nucleoside triphosphate metabolic processGO:00091411440.012
embryonic axis specificationGO:000057810.012
heterocycle catabolic processGO:00467001670.012
ribonucleotide metabolic processGO:00092592310.012
negative regulation of rna biosynthetic processGO:19026791180.012
ribonucleoside metabolic processGO:00091191740.012
aromatic compound catabolic processGO:00194391680.012
response to hydrogen peroxideGO:0042542890.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
regulation of cellular component biogenesisGO:0044087860.012
regulation of anatomical structure sizeGO:00900661350.012
organic substance catabolic processGO:19015753160.012
positive regulation of signal transductionGO:00099671750.011
growthGO:00400071650.011
Fly
regulation of nucleoside metabolic processGO:0009118660.011
positive regulation of intracellular signal transductionGO:19025331380.011
steroid metabolic processGO:0008202730.011
organic cyclic compound catabolic processGO:19013611750.011
regulation of cellular catabolic processGO:00313291010.011
single organism cellular localizationGO:19025801020.011
negative regulation of cell differentiationGO:0045596990.011
protein complex assemblyGO:00064612630.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
urogenital system developmentGO:0001655780.011
protein oligomerizationGO:00512591910.011
peptide transportGO:0015833970.011
regulation of hydrolase activityGO:00513361430.011
organ morphogenesisGO:0009887750.011
protein complex subunit organizationGO:00718223020.011
telencephalon developmentGO:0021537620.011
rhythmic processGO:00485111560.011
cellular response to lipidGO:00713962010.011
reactive oxygen species biosynthetic processGO:190340980.011
response to ketoneGO:19016541820.011
norepinephrine metabolic processGO:004241530.011
positive regulation of programmed cell deathGO:00430681570.011
cellular nitrogen compound catabolic processGO:00442701630.011
positive regulation of kinase activityGO:0033674770.011
negative regulation of cell deathGO:00605482290.011
ribose phosphate biosynthetic processGO:0046390870.011
cellular response to growth factor stimulusGO:00713631620.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
regulation of neuron projection developmentGO:00109751610.011
peptidyl tyrosine modificationGO:0018212720.010
protein localizationGO:00081041910.010
defense responseGO:00069521940.010
response to reactive oxygen speciesGO:00003021200.010
forebrain developmentGO:0030900980.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
protein homooligomerizationGO:0051260910.010
nucleobase containing compound catabolic processGO:00346551520.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
dna metabolic processGO:0006259960.010
Human Fly
response to nutrientGO:00075842480.010
regulation of catabolic processGO:00098941130.010
heart morphogenesisGO:000300730.010
male gamete generationGO:0048232990.010
cardiovascular system developmentGO:00723581340.010
spermatogenesisGO:0007283990.010

Top3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
central nervous system diseaseDOID:33100.012
disease of metabolismDOID:001466700.011