Rattus norvegicus

0 known processes

Top3b

topoisomerase (DNA) III beta

Top3b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.065
rna biosynthetic processGO:00327743800.056
catabolic processGO:00090563510.049
Fly
nucleic acid templated transcriptionGO:00976593790.041
negative regulation of cellular metabolic processGO:00313242810.040
regulation of transcription dna templatedGO:00063553740.040
regulation of rna biosynthetic processGO:20011413810.038
programmed cell deathGO:00125013920.038
organic cyclic compound catabolic processGO:19013611750.036
Fly
purine nucleotide metabolic processGO:00061632290.036
cellular component biogenesisGO:00440853680.036
Fly
macromolecular complex subunit organizationGO:00439333390.035
organophosphate metabolic processGO:00196373700.035
organelle organizationGO:00069962660.034
oxoacid metabolic processGO:00434362900.034
regulation of nucleic acid templated transcriptionGO:19035063800.034
negative regulation of macromolecule metabolic processGO:00106052600.034
regulation of rna metabolic processGO:00512523910.033
nucleotide metabolic processGO:00091172790.031
heterocycle catabolic processGO:00467001670.030
Fly
carboxylic acid metabolic processGO:00197522890.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
macromolecular complex assemblyGO:00650032730.030
secretionGO:00469033070.029
cellular catabolic processGO:00442482950.029
Fly
protein complex subunit organizationGO:00718223020.029
single organism catabolic processGO:00447122830.029
transcription dna templatedGO:00063513770.028
protein localizationGO:00081041910.028
regulation of protein metabolic processGO:00512462890.028
nucleobase containing small molecule metabolic processGO:00550863160.027
negative regulation of nucleobase containing compound metabolic processGO:00459341530.027
negative regulation of metabolic processGO:00098923310.027
protein complex biogenesisGO:00702712630.027
organic substance catabolic processGO:19015753160.027
Fly
regulation of molecular functionGO:00650093980.026
nucleoside phosphate metabolic processGO:00067532830.026
ribonucleotide metabolic processGO:00092592310.026
protein complex assemblyGO:00064612630.025
macromolecule localizationGO:00330362520.025
regulation of phosphate metabolic processGO:00192203490.024
secretion by cellGO:00329402480.024
organonitrogen compound catabolic processGO:19015651790.024
ribose phosphate metabolic processGO:00196932350.024
negative regulation of nitrogen compound metabolic processGO:00511721610.024
carbohydrate derivative metabolic processGO:19011353460.023
cellular amino acid metabolic processGO:00065201070.023
regulation of phosphorus metabolic processGO:00511743490.023
purine nucleoside metabolic processGO:00422781690.023
organic acid metabolic processGO:00060822920.023
nucleoside triphosphate catabolic processGO:00091431230.023
intracellular signal transductionGO:00355563140.023
reproductive processGO:00224143720.023
positive regulation of cellular biosynthetic processGO:00313282950.022
nucleoside catabolic processGO:00091641260.022
neuron differentiationGO:00301823680.022
purine ribonucleoside triphosphate metabolic processGO:00092051400.022
ion transmembrane transportGO:00342203650.022
anatomical structure morphogenesisGO:00096532980.022
ribonucleoside triphosphate metabolic processGO:00091991410.022
cation transportGO:00068123820.022
aromatic compound catabolic processGO:00194391680.022
Fly
single organism reproductive processGO:00447022970.022
nucleoside triphosphate metabolic processGO:00091411440.021
negative regulation of cell deathGO:00605482290.021
purine containing compound metabolic processGO:00725212530.021
regulation of programmed cell deathGO:00430673410.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
purine ribonucleotide metabolic processGO:00091502270.020
central nervous system developmentGO:00074173110.020
transcription from rna polymerase ii promoterGO:00063662520.020
carbohydrate derivative catabolic processGO:19011361470.020
purine ribonucleoside metabolic processGO:00461281680.020
positive regulation of cellular component organizationGO:00511302000.020
Fly
cellular response to stressGO:00335542690.020
positive regulation of biosynthetic processGO:00098913190.020
negative regulation of cellular biosynthetic processGO:00313271610.020
regulation of protein modification processGO:00313991940.019
protein oligomerizationGO:00512591910.019
positive regulation of developmental processGO:00510942830.019
Fly
purine nucleoside catabolic processGO:00061521240.019
cellular response to oxygen containing compoundGO:19017013860.019
amine metabolic processGO:0009308380.019
ribonucleoside catabolic processGO:00424541260.019
regulation of apoptotic processGO:00429813350.019
neuron developmentGO:00486662860.019
protein phosphorylationGO:00064683450.018
nucleotide catabolic processGO:00091661390.018
cellular nitrogen compound catabolic processGO:00442701630.018
Fly
regulation of multicellular organismal developmentGO:20000263760.018
Fly
regulation of signal transductionGO:00099663180.018
single organism organelle organizationGO:19025891800.018
ribonucleotide catabolic processGO:00092611360.018
cellular amine metabolic processGO:0044106380.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
response to oxygen levelsGO:00704822650.018
peptidyl amino acid modificationGO:00181931260.018
regulation of cellular amino acid metabolic processGO:000652120.017
regulation of cellular component organizationGO:00511283680.017
Fly
ribonucleoside metabolic processGO:00091191740.017
nucleoside metabolic processGO:00091161790.017
ras protein signal transductionGO:0007265290.017
positive regulation of multicellular organismal processGO:00512403870.017
Fly
positive regulation of gene expressionGO:00106282440.017
cellular component assemblyGO:00226073600.017
Fly
cell projection organizationGO:00300303020.017
positive regulation of phosphorus metabolic processGO:00105622620.017
neuron projection developmentGO:00311752730.017
glycosyl compound catabolic processGO:19016581260.017
transmembrane transportGO:00550854120.017
regulation of phosphorylationGO:00423252480.017
ribonucleoside triphosphate catabolic processGO:00092031220.017
oxidation reduction processGO:00551143040.017
cellular component movementGO:00069282480.016
response to extracellular stimulusGO:00099913800.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
glycosyl compound metabolic processGO:19016571820.016
positive regulation of protein metabolic processGO:00512471780.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
regulation of catalytic activityGO:00507903040.016
positive regulation of cell differentiationGO:00455972170.016
intracellular transportGO:00469071850.016
purine ribonucleotide catabolic processGO:00091541360.016
apoptotic processGO:00069153810.016
homeostatic processGO:00425923310.016
cellular homeostasisGO:00197252520.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
cellular chemical homeostasisGO:00550822470.015
positive regulation of cellular amine metabolic processGO:003324030.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
regulation of cell differentiationGO:00455953200.015
positive regulation of phosphate metabolic processGO:00459372620.015
regulation of cellular amine metabolic processGO:003323880.015
nucleoside phosphate catabolic processGO:19012921400.015
purine ribonucleoside catabolic processGO:00461301240.015
nucleobase containing compound catabolic processGO:00346551520.015
Fly
amino acid transportGO:0006865700.015
positive regulation of molecular functionGO:00440932300.015
response to inorganic substanceGO:00100353770.015
small gtpase mediated signal transductionGO:0007264360.015
regulation of cellular protein metabolic processGO:00322682670.015
cellular macromolecule localizationGO:00707271220.015
negative regulation of rna metabolic processGO:00512531230.015
purine containing compound catabolic processGO:00725231380.015
cellular ketone metabolic processGO:0042180510.015
purine nucleotide catabolic processGO:00061951360.014
negative regulation of signalingGO:00230571570.014
carboxylic acid transportGO:00469421150.014
cellular protein localizationGO:00346131220.014
growthGO:00400071650.014
positive regulation of cellular protein metabolic processGO:00322701670.014
response to peptide hormoneGO:00434342780.014
regulation of hydrolase activityGO:00513361430.014
response to radiationGO:00093141370.014
multicellular organism reproductionGO:00325042330.014
multi organism reproductive processGO:00447032620.014
multicellular organismal reproductive processGO:00486092330.014
agingGO:00075682410.014
regulation of nucleotide metabolic processGO:00061401170.014
negative regulation of biosynthetic processGO:00098901680.014
regulation of cellular localizationGO:00603412630.014
negative regulation of rna biosynthetic processGO:19026791180.014
positive regulation of phosphorylationGO:00423271770.014
positive regulation of nervous system developmentGO:00519621780.014
Fly
nitrogen compound transportGO:00717052290.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
regulation of cellular ketone metabolic processGO:0010565270.013
response to ethanolGO:00454711620.013
organophosphate catabolic processGO:00464341480.013
negative regulation of apoptotic processGO:00430661810.013
negative regulation of cell communicationGO:00106481580.013
positive regulation of rna metabolic processGO:00512542030.013
single organism biosynthetic processGO:00447113420.013
organic anion transportGO:00157111320.013
proteolysisGO:00065081750.013
cation transmembrane transportGO:00986552630.013
dna metabolic processGO:0006259960.012
Fly
positive regulation of transcription dna templatedGO:00458931970.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
regulation of catabolic processGO:00098941130.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
organic acid transportGO:00158491160.012
negative regulation of response to stimulusGO:00485851550.012
anion transportGO:00068201780.012
regulation of system processGO:00440572080.012
cellular component morphogenesisGO:00329891550.012
negative regulation of molecular functionGO:00440921330.012
positive regulation of neurogenesisGO:00507691650.012
reproductionGO:00000032450.012
regulation of protein kinase activityGO:00458591050.012
cellular response to hormone stimulusGO:00328702470.012
regulation of secretionGO:00510462240.012
cellular response to endogenous stimulusGO:00714953770.012
negative regulation of gene expressionGO:00106291990.012
regulation of neuron differentiationGO:00456642080.012
actin filament based processGO:0030029860.012
positive regulation of rna biosynthetic processGO:19026801970.012
regulation of nervous system developmentGO:00519602640.012
Fly
positive regulation of catalytic activityGO:00430851840.012
cellular response to cytokine stimulusGO:00713451270.012
response to estradiolGO:00323551640.012
regulation of protein phosphorylationGO:00019321830.012
cytoplasmic transportGO:00164821150.012
response to external biotic stimulusGO:00432072210.012
regulation of nucleotide catabolic processGO:0030811650.011
regulation of gtpase activityGO:0043087570.011
synaptic growth at neuromuscular junctionGO:005112410.011
positive regulation of protein modification processGO:00314011420.011
response to decreased oxygen levelsGO:00362932370.011
mapk cascadeGO:00001651400.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
regulation of purine nucleotide metabolic processGO:19005421150.011
response to hexoseGO:00097461440.011
regulation of intracellular signal transductionGO:19025312180.011
regulation of cell proliferationGO:00421273590.011
response to glucocorticoidGO:00513842230.011
locomotionGO:00400112370.011
regulation of membrane potentialGO:00423911100.011
regulation of neuron projection developmentGO:00109751610.011
guanosine containing compound metabolic processGO:1901068740.011
regulation of secretion by cellGO:19035302080.011
response to peptideGO:19016522920.011
multicellular organism growthGO:003526410.011
oligopeptide transportGO:000685740.011
gamete generationGO:00072761240.011
response to oxidative stressGO:00069791860.011
regulation of transferase activityGO:00513381230.011
negative regulation of programmed cell deathGO:00430691830.011
signal releaseGO:00230611450.010
response to acid chemicalGO:00011012220.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
gtp metabolic processGO:0046039720.010
signal transduction by phosphorylationGO:00230141440.010
cellular response to nitrogen compoundGO:19016992100.010
cellular macromolecular complex assemblyGO:0034622580.010
regulation of cell projection organizationGO:00313441750.010
cell growthGO:00160491040.010
chemical homeostasisGO:00488782920.010
cell cell signalingGO:00072673350.010
Fly
regulation of cell developmentGO:00602842630.010
inorganic cation transmembrane transportGO:00986622020.010
negative regulation of catalytic activityGO:00430861030.010
regulation of growthGO:00400081050.010
negative regulation of protein metabolic processGO:00512481140.010

Top3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.033
disease of anatomical entityDOID:700.033
sensory system diseaseDOID:005015500.023
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.016
retinitis pigmentosaDOID:1058400.013
retinal degenerationDOID:846600.013
retinal diseaseDOID:567900.013
central nervous system diseaseDOID:33100.011
musculoskeletal system diseaseDOID:1700.011