Rattus norvegicus

14 known processes

Mme

membrane metallo-endopeptidase

(Aliases: SFE,Nep,CD10,MGC93576)

Mme biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to hypoxiaGO:00016662310.105
Rat
organic acid metabolic processGO:00060822920.105
carboxylic acid metabolic processGO:00197522890.090
oxoacid metabolic processGO:00434362900.087
intracellular signal transductionGO:00355563140.065
Rat
response to metal ionGO:00100382530.064
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.053
Rat
catabolic processGO:00090563510.053
regulation of hormone levelsGO:00108171870.052
anatomical structure morphogenesisGO:00096532980.051
carbohydrate derivative metabolic processGO:19011353460.048
Rat
chemical homeostasisGO:00488782920.047
cellular component movementGO:00069282480.047
rna metabolic processGO:00160704060.047
gland developmentGO:00487321550.047
organelle organizationGO:00069962660.046
positive regulation of signal transductionGO:00099671750.046
Rat
cellular homeostasisGO:00197252520.045
cellular component biogenesisGO:00440853680.045
locomotionGO:00400112370.045
cellular response to endogenous stimulusGO:00714953770.044
cell cell signalingGO:00072673350.042
positive regulation of transportGO:00510502450.042
central nervous system developmentGO:00074173110.041
positive regulation of macromolecule biosynthetic processGO:00105572470.040
response to decreased oxygen levelsGO:00362932370.040
Rat
single organism biosynthetic processGO:00447113420.040
Rat
single organism catabolic processGO:00447122830.040
response to growth factorGO:00708481890.039
cellular catabolic processGO:00442482950.039
nucleic acid templated transcriptionGO:00976593790.039
transcription dna templatedGO:00063513770.039
positive regulation of nucleobase containing compound metabolic processGO:00459353190.038
Rat
regulation of locomotionGO:00400121480.038
cellular amino acid metabolic processGO:00065201070.038
homeostatic processGO:00425923310.038
cellular component assemblyGO:00226073600.037
rna biosynthetic processGO:00327743800.036
regulation of nucleic acid templated transcriptionGO:19035063800.036
nucleobase containing small molecule metabolic processGO:00550863160.036
Rat
positive regulation of nucleic acid templated transcriptionGO:19035081970.036
cellular ion homeostasisGO:00068731840.035
response to inorganic substanceGO:00100353770.035
Rat
response to monosaccharideGO:00342841590.034
positive regulation of biosynthetic processGO:00098913190.034
Rat
regulation of rna metabolic processGO:00512523910.034
ion homeostasisGO:00508012120.034
organic substance catabolic processGO:19015753160.034
cation homeostasisGO:00550801950.034
cellular ketone metabolic processGO:0042180510.033
regulation of cellular component organizationGO:00511283680.033
divalent inorganic cation homeostasisGO:00725071650.033
head developmentGO:00603222470.033
epithelium developmentGO:0060429960.032
response to nutrient levelsGO:00316673700.032
regulation of transcription from rna polymerase ii promoterGO:00063572340.031
ion transmembrane transportGO:00342203650.031
secretionGO:00469033070.030
negative regulation of metabolic processGO:00098923310.029
macromolecular complex subunit organizationGO:00439333390.029
amine metabolic processGO:0009308380.029
cellular cation homeostasisGO:00300031800.029
transmembrane transportGO:00550854120.028
regulation of transcription dna templatedGO:00063553740.028
positive regulation of rna biosynthetic processGO:19026801970.028
regulation of rna biosynthetic processGO:20011413810.028
ribonucleotide metabolic processGO:00092592310.028
Rat
circulatory system processGO:00030131830.027
Rat
cardiovascular system developmentGO:00723581340.027
purine nucleotide metabolic processGO:00061632290.027
Rat
cation transportGO:00068123820.027
response to extracellular stimulusGO:00099913800.027
regulation of cellular amino acid metabolic processGO:000652120.027
localization of cellGO:00516742020.026
cellular amine metabolic processGO:0044106380.026
nucleotide metabolic processGO:00091172790.026
Rat
transcription from rna polymerase ii promoterGO:00063662520.026
rhythmic processGO:00485111560.026
heart morphogenesisGO:000300730.026
blood circulationGO:00080151830.026
Rat
cellular divalent inorganic cation homeostasisGO:00725031620.026
organonitrogen compound catabolic processGO:19015651790.025
small molecule catabolic processGO:0044282590.025
immune system processGO:00023762040.025
positive regulation of rna metabolic processGO:00512542030.025
cellular lipid metabolic processGO:00442552080.025
regulation of cellular protein metabolic processGO:00322682670.024
ribose phosphate metabolic processGO:00196932350.024
Rat
cellular chemical homeostasisGO:00550822470.024
macromolecular complex assemblyGO:00650032730.024
regulation of apoptotic processGO:00429813350.024
cell motilityGO:00488702020.024
regulation of cellular ketone metabolic processGO:0010565270.023
mesoderm developmentGO:000749820.023
cell adhesionGO:00071551100.023
nitrogen compound transportGO:00717052290.023
agingGO:00075682410.023
Human
circulatory system developmentGO:00723591340.023
regulation of cell proliferationGO:00421273590.023
cation transmembrane transportGO:00986552630.023
protein complex assemblyGO:00064612630.022
cell morphogenesisGO:00009021420.022
positive regulation of developmental processGO:00510942830.022
brain developmentGO:00074202470.022
monocarboxylic acid metabolic processGO:00327871520.022
heterocycle catabolic processGO:00467001670.022
lipid metabolic processGO:00066292830.022
nucleoside phosphate metabolic processGO:00067532830.021
Rat
protein phosphorylationGO:00064683450.021
response to carbohydrateGO:00097431830.021
organic cyclic compound catabolic processGO:19013611750.021
positive regulation of cell communicationGO:00106472710.021
Rat
response to glucoseGO:00097491360.021
behaviorGO:00076102050.021
protein complex subunit organizationGO:00718223020.021
positive regulation of phosphorus metabolic processGO:00105622620.020
Rat
regulation of cell differentiationGO:00455953200.020
cell migrationGO:00164771970.020
positive regulation of multicellular organismal processGO:00512403870.020
Rat
response to peptide hormoneGO:00434342780.020
response to hexoseGO:00097461440.020
regulation of secretion by cellGO:19035302080.020
response to glucocorticoidGO:00513842230.020
kidney developmentGO:0001822670.020
Human
purine containing compound metabolic processGO:00725212530.020
Rat
positive regulation of gene expressionGO:00106282440.020
embryonic skeletal system morphogenesisGO:004870430.020
g protein coupled receptor signaling pathwayGO:00071862420.020
Rat
regulation of ion transportGO:00432692450.020
hormone secretionGO:00468791150.020
positive regulation of signalingGO:00230562700.020
Rat
tissue developmentGO:00098882520.020
regulation of cellular localizationGO:00603412630.019
response to alkaloidGO:00432791320.019
cell projection organizationGO:00300303020.019
multi organism reproductive processGO:00447032620.019
positive regulation of cell migrationGO:0030335960.019
response to transition metal nanoparticleGO:19902671220.019
protein complex biogenesisGO:00702712630.019
eye developmentGO:0001654500.019
regulation of cellular amine metabolic processGO:003323880.019
response to ethanolGO:00454711620.019
organophosphate metabolic processGO:00196373700.019
Rat
positive regulation of cellular biosynthetic processGO:00313282950.018
Rat
regulation of signal transductionGO:00099663180.018
Rat
regulation of nervous system developmentGO:00519602640.018
cellular component morphogenesisGO:00329891550.018
regulation of catalytic activityGO:00507903040.018
calcium ion homeostasisGO:00550741620.018
single organism reproductive processGO:00447022970.018
inorganic ion transmembrane transportGO:00986602290.018
positive regulation of cell proliferationGO:00082842490.018
purine ribonucleoside metabolic processGO:00461281680.018
reproductive processGO:00224143720.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.018
negative regulation of gene expressionGO:00106291990.018
regulation of cell migrationGO:00303341280.018
apoptotic processGO:00069153810.017
Rat
negative regulation of cellular biosynthetic processGO:00313271610.017
positive regulation of cellular amine metabolic processGO:003324030.017
dephosphorylationGO:0016311980.017
protein oligomerizationGO:00512591910.017
aromatic compound catabolic processGO:00194391680.017
positive regulation of secretionGO:00510471400.017
positive regulation of molecular functionGO:00440932300.017
hormone transportGO:00099141210.017
positive regulation of phosphate metabolic processGO:00459372620.017
Rat
secretion by cellGO:00329402480.017
sulfur amino acid metabolic processGO:000009690.017
taxisGO:0042330670.017
small gtpase mediated signal transductionGO:0007264360.017
single organism organelle organizationGO:19025891800.017
cardiac chamber developmentGO:000320510.017
regulation of phosphorus metabolic processGO:00511743490.016
Rat
positive regulation of transcription dna templatedGO:00458931970.016
connective tissue developmentGO:0061448330.016
nucleoside metabolic processGO:00091161790.016
renal system developmentGO:0072001670.016
Human
cellular metal ion homeostasisGO:00068751720.016
regulation of cell motilityGO:20001451310.016
regulation of nucleotide metabolic processGO:00061401170.016
Rat
response to estrogenGO:00436272320.016
regulation of multicellular organismal developmentGO:20000263760.016
purine nucleoside metabolic processGO:00422781690.016
embryonic skeletal system developmentGO:004870630.016
neuron developmentGO:00486662860.016
regulation of programmed cell deathGO:00430673410.016
positive regulation of cell differentiationGO:00455972170.016
response to nutrientGO:00075842480.016
sensory organ developmentGO:0007423740.016
ras protein signal transductionGO:0007265290.016
carbohydrate derivative catabolic processGO:19011361470.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
carboxylic acid catabolic processGO:0046395490.016
regulation of cell developmentGO:00602842630.016
regulation of cell morphogenesisGO:0022604770.015
proteolysisGO:00065081750.015
cellular carbohydrate metabolic processGO:0044262720.015
response to oxygen levelsGO:00704822650.015
Rat
regulation of molecular functionGO:00650093980.015
response to hydrogen peroxideGO:0042542890.015
organ morphogenesisGO:0009887750.015
organic anion transportGO:00157111320.015
limb morphogenesisGO:003510840.015
synaptic transmissionGO:00072682350.015
response to acid chemicalGO:00011012220.015
action potentialGO:0001508540.015
regulation of neuron differentiationGO:00456642080.015
cellular response to growth factor stimulusGO:00713631620.015
oxidation reduction processGO:00551143040.015
metal ion transportGO:00300012890.015
cellular response to hormone stimulusGO:00328702470.015
biological adhesionGO:00226101100.015
embryonic appendage morphogenesisGO:003511340.015
response to oxidative stressGO:00069791860.015
protein localizationGO:00081041910.015
purine containing compound catabolic processGO:00725231380.015
mesenchymal cell proliferationGO:001046340.015
cell part morphogenesisGO:00329901230.014
bmp signaling pathwayGO:003050940.014
nucleobase containing compound catabolic processGO:00346551520.014
regulation of purine nucleotide metabolic processGO:19005421150.014
Rat
regulation of cell projection organizationGO:00313441750.014
negative regulation of programmed cell deathGO:00430691830.014
cofactor metabolic processGO:0051186950.014
amide transportGO:00428861050.014
cellular calcium ion homeostasisGO:00068741600.014
cellular response to organic cyclic compoundGO:00714072020.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
cellular response to nitrogen compoundGO:19016992100.014
negative regulation of cell communicationGO:00106481580.014
negative regulation of rna metabolic processGO:00512531230.014
eye morphogenesisGO:004859240.014
positive regulation of cell motilityGO:2000147970.014
positive regulation of response to stimulusGO:00485842850.014
Rat
camera type eye developmentGO:0043010480.014
salivary gland developmentGO:000743130.014
multicellular organism reproductionGO:00325042330.014
axis specificationGO:000979840.014
response to ketoneGO:19016541820.014
ribonucleoside metabolic processGO:00091191740.014
macromolecule localizationGO:00330362520.014
neuron differentiationGO:00301823680.014
peptide secretionGO:0002790860.014
regulation of intracellular signal transductionGO:19025312180.014
Rat
gastrulationGO:000736920.014
neuron projection developmentGO:00311752730.014
organophosphate catabolic processGO:00464341480.014
neurological system processGO:00508772190.013
Mouse
alpha amino acid metabolic processGO:1901605710.013
regulation of membrane potentialGO:00423911100.013
positive regulation of nucleotide metabolic processGO:0045981910.013
Rat
nucleotide catabolic processGO:00091661390.013
response to reactive oxygen speciesGO:00003021200.013
reproductionGO:00000032450.013
anterior posterior pattern specificationGO:000995210.013
multi multicellular organism processGO:00447061380.013
glycosyl compound metabolic processGO:19016571820.013
vesicle mediated transportGO:00161921810.013
chromosome segregationGO:000705920.013
regulation of mapk cascadeGO:00434081160.013
Rat
programmed cell deathGO:00125013920.013
Rat
multicellular organismal reproductive processGO:00486092330.013
regulation of neurogenesisGO:00507672470.013
metal ion homeostasisGO:00550651860.012
purine nucleotide catabolic processGO:00061951360.012
positive regulation of phosphorylationGO:00423271770.012
chemotaxisGO:0006935660.012
appendage morphogenesisGO:003510740.012
regulation of cellular component movementGO:00512701500.012
negative regulation of macromolecule metabolic processGO:00106052600.012
regulation of phosphorylationGO:00423252480.012
Rat
sexual reproductionGO:00199531480.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
positive regulation of mapk cascadeGO:0043410920.012
hepaticobiliary system developmentGO:0061008900.012
carbohydrate derivative biosynthetic processGO:19011371240.012
Rat
regulation of cellular catabolic processGO:00313291010.012
skeletal system developmentGO:0001501410.012
neuromuscular synaptic transmissionGO:000727420.012
ribonucleotide catabolic processGO:00092611360.012
positive regulation of cellular component movementGO:00512721020.012
carbohydrate metabolic processGO:00059751300.012
nucleoside triphosphate catabolic processGO:00091431230.012
regulation of secretionGO:00510462240.012
organic acid catabolic processGO:0016054490.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
regulation of transmembrane transportGO:00347621220.012
purine ribonucleotide metabolic processGO:00091502270.012
Rat
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
organophosphate biosynthetic processGO:00904071430.012
Rat
carbohydrate homeostasisGO:0033500750.012
cellular response to organonitrogen compoundGO:00714171970.012
negative regulation of signalingGO:00230571570.012
cellular response to steroid hormone stimulusGO:0071383930.012
positive regulation of ion transportGO:0043270940.012
positive regulation of cell developmentGO:00107201760.012
organ formationGO:004864530.012
cellular response to oxygen containing compoundGO:19017013860.012
negative regulation of rna biosynthetic processGO:19026791180.012
regulation of protein metabolic processGO:00512462890.012
cell projection morphogenesisGO:00488581230.012
regulation of canonical wnt signaling pathwayGO:006082840.012
cellular nitrogen compound catabolic processGO:00442701630.011
regulation of mesenchymal cell proliferationGO:001046440.011
coenzyme metabolic processGO:0006732860.011
cell morphogenesis involved in differentiationGO:00009041190.011
nucleoside phosphate catabolic processGO:19012921400.011
nucleoside triphosphate metabolic processGO:00091411440.011
gamete generationGO:00072761240.011
single organism carbohydrate metabolic processGO:00447231180.011
blood vessel developmentGO:0001568690.011
actin filament based processGO:0030029860.011
regulation of smooth muscle cell proliferationGO:0048660750.011
multicellular organismal homeostasisGO:0048871490.011
dna metabolic processGO:0006259960.011
formation of primary germ layerGO:000170410.011
glucose homeostasisGO:0042593750.011
lipid biosynthetic processGO:00086101280.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.011
regulation of catabolic processGO:00098941130.011
peptide transportGO:0015833970.011
regulation of response to external stimulusGO:00321011060.011
cellular modified amino acid metabolic processGO:0006575610.011
positive regulation of protein metabolic processGO:00512471780.011
purine ribonucleotide catabolic processGO:00091541360.011
negative regulation of cellular metabolic processGO:00313242810.011
positive regulation of nervous system developmentGO:00519621780.011
carboxylic acid transportGO:00469421150.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
inorganic cation transmembrane transportGO:00986622020.011
response to corticosteroidGO:00319602350.011
liver developmentGO:0001889900.011
positive regulation of secretion by cellGO:19035321280.011
regulation of stem cell differentiationGO:200073620.011
fatty acid metabolic processGO:0006631990.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
positive regulation of cellular protein metabolic processGO:00322701670.011
insecticide metabolic processGO:001714340.011
regulation of system processGO:00440572080.011
Rat
response to peptideGO:19016522920.011
regulation of transferase activityGO:00513381230.010
positive regulation of nucleoside metabolic processGO:0045979550.010
alcohol metabolic processGO:0006066770.010
regulation of protein phosphorylationGO:00019321830.010
cellular response to stressGO:00335542690.010
positive regulation of locomotionGO:00400171020.010
regulation of anatomical structure morphogenesisGO:00226031410.010
organic acid transportGO:00158491160.010
signal releaseGO:00230611450.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
small molecule biosynthetic processGO:00442831240.010
positive regulation of catabolic processGO:0009896780.010
cytoskeleton organizationGO:00070101110.010
morphogenesis of embryonic epitheliumGO:001633130.010
regulation of metal ion transportGO:00109591180.010
tube developmentGO:0035295890.010
anion transportGO:00068201780.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
cardiac ventricle developmentGO:000323110.010
transmission of nerve impulseGO:0019226420.010
cellular hormone metabolic processGO:0034754490.010
spermatogenesisGO:0007283990.010
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.010
cyclic purine nucleotide metabolic processGO:0052652620.010
Rat
positive regulation of catalytic activityGO:00430851840.010
negative regulation of canonical wnt signaling pathwayGO:009009040.010
negative regulation of catalytic activityGO:00430861030.010

Mme disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.025
cancerDOID:16200.025
disease of cellular proliferationDOID:1456600.025
nervous system diseaseDOID:86300.024
disease of anatomical entityDOID:700.024
musculoskeletal system diseaseDOID:1700.019
disease of metabolismDOID:001466700.013
central nervous system diseaseDOID:33100.010