Rattus norvegicus

0 known processes

Mdc1

mediator of DNA damage checkpoint 1

(Aliases: KIAA0170)

Mdc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna biosynthetic processGO:00327743800.080
rna metabolic processGO:00160704060.076
regulation of rna biosynthetic processGO:20011413810.076
nucleic acid templated transcriptionGO:00976593790.075
negative regulation of gene expressionGO:00106291990.074
transcription from rna polymerase ii promoterGO:00063662520.067
oxoacid metabolic processGO:00434362900.065
regulation of nucleic acid templated transcriptionGO:19035063800.064
carboxylic acid metabolic processGO:00197522890.059
regulation of rna metabolic processGO:00512523910.057
regulation of transcription dna templatedGO:00063553740.054
transcription dna templatedGO:00063513770.053
negative regulation of macromolecule biosynthetic processGO:00105581480.049
negative regulation of cellular biosynthetic processGO:00313271610.045
negative regulation of biosynthetic processGO:00098901680.045
organic substance catabolic processGO:19015753160.045
negative regulation of metabolic processGO:00098923310.042
organic acid metabolic processGO:00060822920.041
regulation of cellular component organizationGO:00511283680.041
positive regulation of gene expressionGO:00106282440.041
negative regulation of rna metabolic processGO:00512531230.041
positive regulation of biosynthetic processGO:00098913190.041
organelle organizationGO:00069962660.040
negative regulation of cellular metabolic processGO:00313242810.040
regulation of transcription from rna polymerase ii promoterGO:00063572340.038
head developmentGO:00603222470.037
carbohydrate derivative metabolic processGO:19011353460.036
central nervous system developmentGO:00074173110.036
positive regulation of nitrogen compound metabolic processGO:00511733340.035
organophosphate metabolic processGO:00196373700.035
cellular amino acid metabolic processGO:00065201070.034
nucleobase containing small molecule metabolic processGO:00550863160.034
negative regulation of nitrogen compound metabolic processGO:00511721610.034
regulation of cell developmentGO:00602842630.033
macromolecular complex subunit organizationGO:00439333390.033
negative regulation of macromolecule metabolic processGO:00106052600.032
regulation of nervous system developmentGO:00519602640.031
response to acid chemicalGO:00011012220.031
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
positive regulation of developmental processGO:00510942830.030
intracellular signal transductionGO:00355563140.030
nucleotide metabolic processGO:00091172790.030
dna metabolic processGO:0006259960.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.029
cellular response to oxygen containing compoundGO:19017013860.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.029
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.029
reproductionGO:00000032450.029
neuron differentiationGO:00301823680.028
cell projection organizationGO:00300303020.028
positive regulation of rna metabolic processGO:00512542030.028
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.028
regulation of cellular amine metabolic processGO:003323880.027
nucleoside phosphate metabolic processGO:00067532830.027
mechanoreceptor differentiationGO:004249020.027
single organism catabolic processGO:00447122830.027
macromolecular complex assemblyGO:00650032730.026
cellular response to stressGO:00335542690.026
regulation of cell differentiationGO:00455953200.025
negative regulation of nucleobase containing compound metabolic processGO:00459341530.025
positive regulation of transcription dna templatedGO:00458931970.025
positive regulation of nervous system developmentGO:00519621780.025
positive regulation of cellular biosynthetic processGO:00313282950.025
positive regulation of cell differentiationGO:00455972170.025
protein complex biogenesisGO:00702712630.025
regulation of cellular ketone metabolic processGO:0010565270.024
negative regulation of rna biosynthetic processGO:19026791180.024
regulation of molecular functionGO:00650093980.024
positive regulation of rna biosynthetic processGO:19026801970.024
chromosome segregationGO:000705920.024
response to estrogenGO:00436272320.024
catabolic processGO:00090563510.023
cellular catabolic processGO:00442482950.023
brain developmentGO:00074202470.023
positive regulation of multicellular organismal processGO:00512403870.023
cofactor metabolic processGO:0051186950.023
single organism intracellular transportGO:19025821660.023
regulation of proteasomal protein catabolic processGO:006113640.022
response to molecule of bacterial originGO:00022371940.022
purine containing compound metabolic processGO:00725212530.022
nucleoside metabolic processGO:00091161790.022
anatomical structure morphogenesisGO:00096532980.022
macromolecule localizationGO:00330362520.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.021
negative regulation of transcription dna templatedGO:00458921160.021
purine nucleotide metabolic processGO:00061632290.021
single organism organelle organizationGO:19025891800.021
regulation of multicellular organismal developmentGO:20000263760.021
positive regulation of cellular component organizationGO:00511302000.021
response to peptide hormoneGO:00434342780.021
reproductive processGO:00224143720.020
cellular component biogenesisGO:00440853680.020
response to extracellular stimulusGO:00099913800.020
regulation of cellular amino acid metabolic processGO:000652120.020
cellular response to endogenous stimulusGO:00714953770.020
multicellular organism reproductionGO:00325042330.020
cellular modified amino acid metabolic processGO:0006575610.020
cellular response to hormone stimulusGO:00328702470.020
intracellular transportGO:00469071850.020
neuron projection developmentGO:00311752730.020
purine nucleoside metabolic processGO:00422781690.020
cellular amine metabolic processGO:0044106380.020
ribose phosphate metabolic processGO:00196932350.019
response to nutrient levelsGO:00316673700.019
ribonucleotide metabolic processGO:00092592310.019
purine ribonucleotide metabolic processGO:00091502270.019
double strand break repairGO:000630210.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
agingGO:00075682410.019
neuron developmentGO:00486662860.019
response to biotic stimulusGO:00096072260.019
cellular ketone metabolic processGO:0042180510.019
regulation of apoptotic processGO:00429813350.019
positive regulation of cell developmentGO:00107201760.019
cellular nitrogen compound catabolic processGO:00442701630.019
regulation of protein metabolic processGO:00512462890.019
regulation of phosphorus metabolic processGO:00511743490.018
locomotionGO:00400112370.018
protein complex assemblyGO:00064612630.018
amine metabolic processGO:0009308380.018
single organism reproductive processGO:00447022970.018
response to nutrientGO:00075842480.018
regulation of neurogenesisGO:00507672470.018
chemical homeostasisGO:00488782920.018
small gtpase mediated signal transductionGO:0007264360.018
cellular component movementGO:00069282480.018
protein complex subunit organizationGO:00718223020.018
regulation of programmed cell deathGO:00430673410.017
spindle organizationGO:000705120.017
programmed cell deathGO:00125013920.017
response to other organismGO:00517072200.017
organic cyclic compound catabolic processGO:19013611750.017
regulation of neuron differentiationGO:00456642080.017
regulation of catalytic activityGO:00507903040.017
taxisGO:0042330670.017
coenzyme metabolic processGO:0006732860.017
cellular macromolecule localizationGO:00707271220.017
nucleobase containing compound catabolic processGO:00346551520.017
multicellular organismal reproductive processGO:00486092330.017
anterior posterior pattern specificationGO:000995210.016
regulation of signal transductionGO:00099663180.016
cellular component assemblyGO:00226073600.016
chromosome organizationGO:0051276360.016
response to lipopolysaccharideGO:00324961910.016
apoptotic processGO:00069153810.016
alpha amino acid metabolic processGO:1901605710.016
ribonucleoside metabolic processGO:00091191740.016
response to bacteriumGO:00096172000.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
response to inorganic substanceGO:00100353770.016
positive regulation of neurogenesisGO:00507691650.016
response to vitaminGO:00332731310.016
heterocycle catabolic processGO:00467001670.016
gastrulationGO:000736920.016
inner ear receptor cell differentiationGO:006011320.015
positive regulation of molecular functionGO:00440932300.015
glycosyl compound metabolic processGO:19016571820.015
organonitrogen compound catabolic processGO:19015651790.015
tissue developmentGO:00098882520.015
multi organism reproductive processGO:00447032620.015
cell motilityGO:00488702020.015
nucleoside triphosphate catabolic processGO:00091431230.015
nitrogen compound transportGO:00717052290.015
protein localizationGO:00081041910.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
positive regulation of cell proliferationGO:00082842490.015
response to external biotic stimulusGO:00432072210.014
regulation of cell projection organizationGO:00313441750.014
microtubule organizing center organizationGO:003102310.014
secretionGO:00469033070.014
carbohydrate derivative catabolic processGO:19011361470.014
cell cell signalingGO:00072673350.014
tube developmentGO:0035295890.014
response to metal ionGO:00100382530.014
positive regulation of cellular amine metabolic processGO:003324030.014
sulfur compound metabolic processGO:0006790700.014
protein oligomerizationGO:00512591910.014
regulation of neuron projection developmentGO:00109751610.014
response to ketoneGO:19016541820.014
positive regulation of protein metabolic processGO:00512471780.014
positive regulation of neuron differentiationGO:00456661260.014
protein phosphorylationGO:00064683450.014
glycosyl compound catabolic processGO:19016581260.014
peptidyl amino acid modificationGO:00181931260.014
epithelium developmentGO:0060429960.013
regulation of anatomical structure morphogenesisGO:00226031410.013
establishment of protein localizationGO:00451841410.013
cellular homeostasisGO:00197252520.013
single organism biosynthetic processGO:00447113420.013
axis specificationGO:000979840.013
purine ribonucleoside catabolic processGO:00461301240.013
negative regulation of multicellular organismal processGO:00512412030.013
ras protein signal transductionGO:0007265290.013
proteolysisGO:00065081750.013
single organism cellular localizationGO:19025801020.013
positive regulation of response to stimulusGO:00485842850.013
carbohydrate derivative biosynthetic processGO:19011371240.013
tube formationGO:003514830.013
gland developmentGO:00487321550.013
regulation of cellular protein metabolic processGO:00322682670.013
nucleoside triphosphate metabolic processGO:00091411440.013
positive regulation of protein modification processGO:00314011420.013
response to corticosteroidGO:00319602350.013
negative regulation of cell communicationGO:00106481580.013
cellular response to nitrogen compoundGO:19016992100.013
positive regulation of signalingGO:00230562700.013
regulation of phosphate metabolic processGO:00192203490.013
vesicle mediated transportGO:00161921810.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
reactive oxygen species metabolic processGO:0072593370.013
ribonucleoside catabolic processGO:00424541260.013
cytoplasmic transportGO:00164821150.012
nuclear transportGO:0051169490.012
cell cycleGO:00070491010.012
meiotic cell cycle processGO:190304630.012
negative regulation of cellular component organizationGO:0051129830.012
regulation of cellular localizationGO:00603412630.012
mitotic spindle organizationGO:000705220.012
positive regulation of neuron projection developmentGO:0010976990.012
regulation of cell cycleGO:0051726730.012
negative regulation of transportGO:00510511360.012
protein transportGO:00150311320.012
aromatic compound catabolic processGO:00194391680.012
urogenital system developmentGO:0001655780.012
gamete generationGO:00072761240.012
oligopeptide transportGO:000685740.012
negative regulation of programmed cell deathGO:00430691830.012
regulation of phosphorylationGO:00423252480.012
positive regulation of catalytic activityGO:00430851840.012
morphogenesis of embryonic epitheliumGO:001633130.012
cell morphogenesis involved in differentiationGO:00009041190.012
ribonucleoside triphosphate catabolic processGO:00092031220.011
nucleoside monophosphate metabolic processGO:0009123930.011
negative regulation of developmental processGO:00510931250.011
small molecule biosynthetic processGO:00442831240.011
response to peptideGO:19016522920.011
embryonic pattern specificationGO:000988010.011
regulation of cell proliferationGO:00421273590.011
cell cycle checkpointGO:000007520.011
eye morphogenesisGO:004859240.011
heart morphogenesisGO:000300730.011
negative regulation of signalingGO:00230571570.011
endocytosisGO:0006897840.011
sexual reproductionGO:00199531480.011
organophosphate catabolic processGO:00464341480.011
nucleoside catabolic processGO:00091641260.011
limb morphogenesisGO:003510840.011
homeostatic processGO:00425923310.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
purine ribonucleoside metabolic processGO:00461281680.011
metal ion transportGO:00300012890.011
purine nucleoside catabolic processGO:00061521240.011
positive regulation of cellular protein metabolic processGO:00322701670.011
response to ethanolGO:00454711620.011
regulation of intracellular signal transductionGO:19025312180.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
circulatory system developmentGO:00723591340.011
developmental process involved in reproductionGO:00030061590.010
response to cytokineGO:00340972150.010
purine nucleotide catabolic processGO:00061951360.010
histone h3 k9 methylationGO:005156710.010
cation transportGO:00068123820.010
carboxylic acid transportGO:00469421150.010
response to oxidative stressGO:00069791860.010
cellular chemical homeostasisGO:00550822470.010
chromatin assembly or disassemblyGO:000633310.010
inner ear morphogenesisGO:004247210.010
organic acid transportGO:00158491160.010
positive regulation of phosphate metabolic processGO:00459372620.010
multicellular organism growthGO:003526410.010

Mdc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
organ system cancerDOID:005068600.015
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014
gastrointestinal system cancerDOID:311900.014
intestinal cancerDOID:1015500.014
sensory system diseaseDOID:005015500.011