Rattus norvegicus

0 known processes

Adam4

a disintegrin and metalloprotease domain 4

(Aliases: MGC125044,tMDCV)

Adam4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.068
programmed cell deathGO:00125013920.064
Rat
organic acid metabolic processGO:00060822920.064
rna biosynthetic processGO:00327743800.057
carboxylic acid metabolic processGO:00197522890.057
cell cell signalingGO:00072673350.050
negative regulation of macromolecule metabolic processGO:00106052600.048
negative regulation of metabolic processGO:00098923310.048
cellular response to endogenous stimulusGO:00714953770.046
response to other organismGO:00517072200.045
nucleobase containing small molecule metabolic processGO:00550863160.044
regulation of cell differentiationGO:00455953200.044
regulation of rna metabolic processGO:00512523910.042
macromolecular complex assemblyGO:00650032730.039
transcription dna templatedGO:00063513770.039
intracellular signal transductionGO:00355563140.038
regulation of nucleic acid templated transcriptionGO:19035063800.037
regulation of rna biosynthetic processGO:20011413810.037
response to external biotic stimulusGO:00432072210.036
positive regulation of cellular biosynthetic processGO:00313282950.036
cellular component assemblyGO:00226073600.036
cellular component biogenesisGO:00440853680.036
macromolecular complex subunit organizationGO:00439333390.035
response to nutrient levelsGO:00316673700.035
regulation of cellular component organizationGO:00511283680.035
regulation of apoptotic processGO:00429813350.035
Rat
cellular response to oxygen containing compoundGO:19017013860.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
response to glucocorticoidGO:00513842230.035
purine containing compound metabolic processGO:00725212530.034
cellular amino acid metabolic processGO:00065201070.034
neuron differentiationGO:00301823680.033
regulation of hormone levelsGO:00108171870.033
nucleic acid templated transcriptionGO:00976593790.032
transmembrane transportGO:00550854120.032
regulation of transcription dna templatedGO:00063553740.032
cell projection organizationGO:00300303020.031
negative regulation of cellular metabolic processGO:00313242810.031
negative regulation of macromolecule biosynthetic processGO:00105581480.031
regulation of molecular functionGO:00650093980.031
protein complex subunit organizationGO:00718223020.031
catabolic processGO:00090563510.031
response to biotic stimulusGO:00096072260.030
organophosphate metabolic processGO:00196373700.030
nucleoside phosphate metabolic processGO:00067532830.030
oxoacid metabolic processGO:00434362900.029
anatomical structure morphogenesisGO:00096532980.029
positive regulation of biosynthetic processGO:00098913190.029
negative regulation of biosynthetic processGO:00098901680.029
negative regulation of gene expressionGO:00106291990.028
neuron developmentGO:00486662860.027
neuron projection developmentGO:00311752730.027
cation transportGO:00068123820.027
response to nutrientGO:00075842480.026
cellular response to nitrogen compoundGO:19016992100.026
positive regulation of nitrogen compound metabolic processGO:00511733340.025
response to lipopolysaccharideGO:00324961910.025
homeostatic processGO:00425923310.025
negative regulation of cell deathGO:00605482290.025
Rat
protein complex assemblyGO:00064612630.024
organic substance catabolic processGO:19015753160.024
regulation of programmed cell deathGO:00430673410.024
Rat
cell morphogenesisGO:00009021420.024
macromolecule localizationGO:00330362520.024
cellular amine metabolic processGO:0044106380.024
regulation of multicellular organismal developmentGO:20000263760.024
cellular response to stressGO:00335542690.023
response to estrogenGO:00436272320.023
purine ribonucleotide metabolic processGO:00091502270.023
cellular catabolic processGO:00442482950.023
purine nucleotide metabolic processGO:00061632290.023
negative regulation of programmed cell deathGO:00430691830.023
Rat
ribose phosphate metabolic processGO:00196932350.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
metal ion transportGO:00300012890.023
ribonucleotide metabolic processGO:00092592310.023
regulation of cell developmentGO:00602842630.023
negative regulation of nitrogen compound metabolic processGO:00511721610.022
carbohydrate derivative metabolic processGO:19011353460.022
secretion by cellGO:00329402480.022
nucleotide metabolic processGO:00091172790.022
regulation of cellular amino acid metabolic processGO:000652120.022
response to extracellular stimulusGO:00099913800.021
purine ribonucleoside metabolic processGO:00461281680.021
positive regulation of cell differentiationGO:00455972170.021
cellular response to corticosteroid stimulusGO:0071384690.021
cellular ketone metabolic processGO:0042180510.021
cellular response to hormone stimulusGO:00328702470.020
regulation of cellular ketone metabolic processGO:0010565270.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
regulation of catalytic activityGO:00507903040.020
negative regulation of transcription dna templatedGO:00458921160.020
response to corticosteroidGO:00319602350.020
axis specificationGO:000979840.020
positive regulation of cellular amine metabolic processGO:003324030.020
nucleoside metabolic processGO:00091161790.020
regulation of vesicle mediated transportGO:0060627810.020
positive regulation of gene expressionGO:00106282440.019
protein oligomerizationGO:00512591910.019
regulation of phosphorus metabolic processGO:00511743490.019
organonitrogen compound biosynthetic processGO:19015661670.019
ion transmembrane transportGO:00342203650.019
negative regulation of multicellular organismal processGO:00512412030.019
purine nucleoside metabolic processGO:00422781690.019
protein localizationGO:00081041910.019
response to oxygen levelsGO:00704822650.019
regulation of nervous system developmentGO:00519602640.019
positive regulation of transcription dna templatedGO:00458931970.018
amine metabolic processGO:0009308380.018
response to molecule of bacterial originGO:00022371940.018
multicellular organismal reproductive processGO:00486092330.018
response to bacteriumGO:00096172000.018
ras protein signal transductionGO:0007265290.018
cellular response to organic cyclic compoundGO:00714072020.018
reproductionGO:00000032450.018
protein complex biogenesisGO:00702712630.018
transcription from rna polymerase ii promoterGO:00063662520.018
positive regulation of molecular functionGO:00440932300.018
organelle organizationGO:00069962660.017
positive regulation of rna metabolic processGO:00512542030.017
defense responseGO:00069521940.017
cellular component movementGO:00069282480.017
regulation of system processGO:00440572080.017
protein phosphorylationGO:00064683450.017
regulation of transcription from rna polymerase ii promoterGO:00063572340.017
response to hypoxiaGO:00016662310.017
hormone secretionGO:00468791150.017
single organism catabolic processGO:00447122830.017
cellular response to alcoholGO:0097306870.017
regulation of cellular amine metabolic processGO:003323880.017
regenerationGO:00310991630.017
regulation of phosphate metabolic processGO:00192203490.017
response to peptideGO:19016522920.017
positive regulation of cellular component organizationGO:00511302000.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
positive regulation of cell communicationGO:00106472710.017
divalent inorganic cation transportGO:00725111340.017
single organism organelle organizationGO:19025891800.017
multicellular organism reproductionGO:00325042330.017
inorganic cation transmembrane transportGO:00986622020.016
response to acid chemicalGO:00011012220.016
response to metal ionGO:00100382530.016
glycosyl compound metabolic processGO:19016571820.016
eye morphogenesisGO:004859240.016
multi organism reproductive processGO:00447032620.016
sex differentiationGO:00075481130.016
positive regulation of cell developmentGO:00107201760.016
negative regulation of apoptotic processGO:00430661810.016
Rat
secretionGO:00469033070.016
neurological system processGO:00508772190.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
regulation of membrane potentialGO:00423911100.016
hormone metabolic processGO:0042445690.016
establishment of protein localizationGO:00451841410.016
g protein coupled receptor signaling pathwayGO:00071862420.016
positive regulation of multicellular organismal processGO:00512403870.016
chemical homeostasisGO:00488782920.016
ribonucleoside metabolic processGO:00091191740.015
negative regulation of cellular biosynthetic processGO:00313271610.015
brain developmentGO:00074202470.015
regulation of neurogenesisGO:00507672470.015
regulation of neuron differentiationGO:00456642080.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
regulation of secretion by cellGO:19035302080.015
reproductive processGO:00224143720.015
regulation of cell proliferationGO:00421273590.015
regulation of signal transductionGO:00099663180.015
response to vitaminGO:00332731310.015
single organism reproductive processGO:00447022970.015
regulation of catabolic processGO:00098941130.015
intracellular transportGO:00469071850.015
positive regulation of signalingGO:00230562700.015
response to hexoseGO:00097461440.015
positive regulation of rna biosynthetic processGO:19026801970.015
anion transportGO:00068201780.015
response to inorganic substanceGO:00100353770.015
cellular response to growth factor stimulusGO:00713631620.015
amide transportGO:00428861050.014
negative regulation of response to stimulusGO:00485851550.014
organic cyclic compound catabolic processGO:19013611750.014
regulation of cellular protein metabolic processGO:00322682670.014
positive regulation of developmental processGO:00510942830.014
response to glucoseGO:00097491360.014
positive regulation of catalytic activityGO:00430851840.014
cellular response to glucocorticoid stimulusGO:0071385680.014
gastrulationGO:000736920.014
maintenance of locationGO:0051235170.014
inorganic ion transmembrane transportGO:00986602290.014
synaptic transmissionGO:00072682350.014
cellular homeostasisGO:00197252520.014
inflammatory responseGO:00069541500.014
response to decreased oxygen levelsGO:00362932370.014
negative regulation of rna metabolic processGO:00512531230.014
regulation of neuron projection developmentGO:00109751610.014
positive regulation of transportGO:00510502450.013
vesicle mediated transportGO:00161921810.013
response to carbohydrateGO:00097431830.013
response to purine containing compoundGO:00140741260.013
heterocycle catabolic processGO:00467001670.013
regulation of protein modification processGO:00313991940.013
response to radiationGO:00093141370.013
positive regulation of phosphate metabolic processGO:00459372620.013
regulation of peptide transportGO:0090087870.013
cellular macromolecule localizationGO:00707271220.013
positive regulation of cell proliferationGO:00082842490.013
apoptotic processGO:00069153810.013
Rat
cellular response to steroid hormone stimulusGO:0071383930.013
growthGO:00400071650.013
organonitrogen compound catabolic processGO:19015651790.013
tube developmentGO:0035295890.013
lipid metabolic processGO:00066292830.013
head developmentGO:00603222470.013
locomotionGO:00400112370.013
hormone transportGO:00099141210.013
agingGO:00075682410.013
regulation of nucleotide metabolic processGO:00061401170.013
cell migrationGO:00164771970.013
positive regulation of secretion by cellGO:19035321280.013
regulation of hydrolase activityGO:00513361430.013
positive regulation of cell deathGO:00109421840.013
sexual reproductionGO:00199531480.013
gamete generationGO:00072761240.013
response to growth factorGO:00708481890.013
single organism intracellular transportGO:19025821660.013
proteolysisGO:00065081750.013
Rat
actin filament based processGO:0030029860.013
purine nucleotide biosynthetic processGO:0006164830.013
circulatory system processGO:00030131830.013
cell morphogenesis involved in differentiationGO:00009041190.012
response to cytokineGO:00340972150.012
nitrogen compound transportGO:00717052290.012
positive regulation of response to stimulusGO:00485842850.012
cellular calcium ion homeostasisGO:00068741600.012
cellular response to peptideGO:19016531330.012
central nervous system developmentGO:00074173110.012
regulation of locomotionGO:00400121480.012
cell cycle checkpointGO:000007520.012
positive regulation of phosphorus metabolic processGO:00105622620.012
oxidation reduction processGO:00551143040.012
mapk cascadeGO:00001651400.012
cell activationGO:0001775970.012
negative regulation of rna biosynthetic processGO:19026791180.012
carbohydrate metabolic processGO:00059751300.012
regulation of hormone secretionGO:00468831060.012
response to peptide hormoneGO:00434342780.012
regulation of secretionGO:00510462240.012
regulation of anatomical structure morphogenesisGO:00226031410.012
cytoplasmic transportGO:00164821150.011
peptide transportGO:0015833970.011
protein transportGO:00150311320.011
aromatic compound catabolic processGO:00194391680.011
sensory perceptionGO:00076001010.011
embryonic pattern specificationGO:000988010.011
blood circulationGO:00080151830.011
cellular response to lipidGO:00713962010.011
purine ribonucleoside catabolic processGO:00461301240.011
organic anion transportGO:00157111320.011
signal releaseGO:00230611450.011
monosaccharide metabolic processGO:0005996610.011
cytoskeleton organizationGO:00070101110.011
positive regulation of protein metabolic processGO:00512471780.011
response to activityGO:0014823730.011
regulation of ion transportGO:00432692450.011
response to insulinGO:00328681330.011
multicellular organism growthGO:003526410.011
lipid storageGO:001991510.011
cellular response to organonitrogen compoundGO:00714171970.011
actin cytoskeleton organizationGO:0030036730.011
single organism biosynthetic processGO:00447113420.011
negative regulation of molecular functionGO:00440921330.011
regulation of cell projection organizationGO:00313441750.011
male gamete generationGO:0048232990.011
behaviorGO:00076102050.011
organophosphate biosynthetic processGO:00904071430.011
spermatogenesisGO:0007283990.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
response to oxidative stressGO:00069791860.011
peptide hormone secretionGO:0030072840.011
action potentialGO:0001508540.011
cellular response to ketoneGO:1901655510.011
monocarboxylic acid metabolic processGO:00327871520.011
response to toxic substanceGO:00096361330.010
immune responseGO:00069551040.010
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
small gtpase mediated signal transductionGO:0007264360.010
neuron deathGO:00709971270.010
regulation of neuron deathGO:19012141150.010
cell part morphogenesisGO:00329901230.010
nucleobase containing compound catabolic processGO:00346551520.010
regulation of anatomical structure sizeGO:00900661350.010
cellular nitrogen compound catabolic processGO:00442701630.010
insulin secretionGO:0030073690.010
negative regulation of catalytic activityGO:00430861030.010
negative regulation of cellular protein metabolic processGO:00322691060.010
gonad developmentGO:00084061040.010
multicellular organismal signalingGO:0035637440.010
cation homeostasisGO:00550801950.010
circadian rhythmGO:0007623880.010
cellular component morphogenesisGO:00329891550.010
positive regulation of programmed cell deathGO:00430681570.010
activation of cysteine type endopeptidase activityGO:009720240.010
spindle organizationGO:000705120.010
cellular protein localizationGO:00346131220.010

Adam4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
nervous system diseaseDOID:86300.042
central nervous system diseaseDOID:33100.017
disease of metabolismDOID:001466700.013
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012