Rattus norvegicus

116 known processes

Pde1c

phosphodiesterase 1C

Pde1c biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular calcium ion homeostasisGO:00068741600.468
metal ion homeostasisGO:00550651860.441
positive regulation of cytosolic calcium ion concentrationGO:00072041220.418
ion transmembrane transportGO:00342203650.356
divalent inorganic cation homeostasisGO:00725071650.334
cytosolic calcium ion homeostasisGO:00514801400.310
cellular component movementGO:00069282480.289
divalent metal ion transportGO:00708381320.266
reproductionGO:00000032450.237
cation transmembrane transportGO:00986552630.197
cellular divalent inorganic cation homeostasisGO:00725031620.195
muscle system processGO:00030121150.185
transmembrane transportGO:00550854120.179
calcium ion homeostasisGO:00550741620.179
cellular response to hormone stimulusGO:00328702470.175
single organism carbohydrate metabolic processGO:00447231180.171
cation homeostasisGO:00550801950.163
regulation of metal ion transportGO:00109591180.156
purine containing compound metabolic processGO:00725212530.150
cellular ion homeostasisGO:00068731840.147
carbohydrate derivative metabolic processGO:19011353460.142
ion homeostasisGO:00508012120.131
positive regulation of response to stimulusGO:00485842850.130
cation transportGO:00068123820.127
inorganic ion transmembrane transportGO:00986602290.126
regulation of heart contractionGO:0008016480.124
regulation of hormone secretionGO:00468831060.115
regulation of secretionGO:00510462240.112
regulation of cellular localizationGO:00603412630.112
protein heterooligomerizationGO:0051291890.109
response to metal ionGO:00100382530.109
carbohydrate metabolic processGO:00059751300.107
positive regulation of signalingGO:00230562700.106
tissue developmentGO:00098882520.105
metal ion transportGO:00300012890.097
macromolecular complex subunit organizationGO:00439333390.097
regulation of molecular functionGO:00650093980.093
response to radiationGO:00093141370.088
monovalent inorganic cation transportGO:00156721720.088
muscle contractionGO:0006936880.083
synaptic transmissionGO:00072682350.077
reproductive processGO:00224143720.076
regulation of muscle contractionGO:0006937530.076
chemical homeostasisGO:00488782920.073
protein complex subunit organizationGO:00718223020.072
regulation of catalytic activityGO:00507903040.072
purine nucleotide metabolic processGO:00061632290.071
positive regulation of transportGO:00510502450.070
regulation of phosphate metabolic processGO:00192203490.069
regulation of multicellular organismal developmentGO:20000263760.069
calcium ion importGO:0070509220.068
intracellular signal transductionGO:00355563140.068
Rat
positive regulation of cell communicationGO:00106472710.067
regulation of nucleic acid templated transcriptionGO:19035063800.066
regulation of membrane potentialGO:00423911100.065
homeostatic processGO:00425923310.065
phasic smooth muscle contractionGO:001482130.064
cellular metal ion homeostasisGO:00068751720.062
cellular chemical homeostasisGO:00550822470.062
brain developmentGO:00074202470.062
positive regulation of transcription dna templatedGO:00458931970.061
cell cell signalingGO:00072673350.060
nucleic acid templated transcriptionGO:00976593790.060
response to glucocorticoidGO:00513842230.059
response to peptide hormoneGO:00434342780.059
oxoacid metabolic processGO:00434362900.058
single organism reproductive processGO:00447022970.057
rna biosynthetic processGO:00327743800.057
ribose phosphate metabolic processGO:00196932350.057
head developmentGO:00603222470.056
positive regulation of intracellular signal transductionGO:19025331380.056
heterocycle catabolic processGO:00467001670.056
nucleoside phosphate metabolic processGO:00067532830.056
action potentialGO:0001508540.055
positive regulation of biosynthetic processGO:00098913190.055
organophosphate biosynthetic processGO:00904071430.054
cellular homeostasisGO:00197252520.054
cell projection organizationGO:00300303020.054
potassium ion transmembrane transportGO:0071805710.053
neuron projection developmentGO:00311752730.053
pancreatic a cell differentiationGO:000331010.052
organophosphate catabolic processGO:00464341480.052
response to inorganic substanceGO:00100353770.052
regulation of cell developmentGO:00602842630.051
organophosphate metabolic processGO:00196373700.051
regulation of ion transportGO:00432692450.051
signal releaseGO:00230611450.051
blood circulationGO:00080151830.050
single organism catabolic processGO:00447122830.050
multicellular organismal reproductive processGO:00486092330.050
cellular potassium ion transportGO:0071804720.049
multi organism reproductive processGO:00447032620.049
forebrain developmentGO:0030900980.048
transcription from rna polymerase ii promoterGO:00063662520.048
heart processGO:0003015570.047
calcium ion transport into cytosolGO:0060402380.047
positive regulation of molecular functionGO:00440932300.046
development of primary sexual characteristicsGO:00451371070.046
regulation of hormone levelsGO:00108171870.046
peptide hormone secretionGO:0030072840.046
catabolic processGO:00090563510.046
cytoskeleton organizationGO:00070101110.045
response to decreased oxygen levelsGO:00362932370.045
response to histamineGO:003477630.045
positive regulation of neurogenesisGO:00507691650.045
regulation of rna metabolic processGO:00512523910.044
organonitrogen compound biosynthetic processGO:19015661670.044
positive regulation of developmental processGO:00510942830.044
cellular response to organonitrogen compoundGO:00714171970.044
response to cytokineGO:00340972150.044
positive regulation of cell developmentGO:00107201760.043
positive regulation of phosphate metabolic processGO:00459372620.043
growthGO:00400071650.043
regulation of phosphorus metabolic processGO:00511743490.043
camp metabolic processGO:0046058630.042
inorganic cation transmembrane transportGO:00986622020.042
regulation of cellular component movementGO:00512701500.042
adult locomotory behaviorGO:000834440.042
regulation of signal transductionGO:00099663180.042
regulation of transcription dna templatedGO:00063553740.042
regulation of ion transmembrane transportGO:00347651210.042
nucleobase containing small molecule metabolic processGO:00550863160.041
rna metabolic processGO:00160704060.041
response to corticosteroidGO:00319602350.041
nucleoside phosphate biosynthetic processGO:19012931020.041
single organism organelle organizationGO:19025891800.040
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.040
immune system processGO:00023762040.040
nucleotide metabolic processGO:00091172790.040
response to lipopolysaccharideGO:00324961910.039
nitrogen compound transportGO:00717052290.039
central nervous system developmentGO:00074173110.039
heart contractionGO:0060047570.039
protein complex assemblyGO:00064612630.039
response to woundingGO:00096112540.038
cell migrationGO:00164771970.038
cellular response to oxygen containing compoundGO:19017013860.038
regulation of cellular component organizationGO:00511283680.038
sensory perception of painGO:0019233730.038
oxidation reduction processGO:00551143040.038
protein oligomerizationGO:00512591910.038
phototransduction visible lightGO:000760320.038
cyclic purine nucleotide metabolic processGO:0052652620.038
sexual reproductionGO:00199531480.037
response to nicotineGO:0035094510.037
actin filament based processGO:0030029860.037
secretionGO:00469033070.036
cellular cation homeostasisGO:00300031800.036
regulation of nervous system developmentGO:00519602640.036
neuron developmentGO:00486662860.036
defecationGO:003042110.036
inflammatory responseGO:00069541500.036
positive regulation of nucleic acid templated transcriptionGO:19035081970.036
single organism biosynthetic processGO:00447113420.035
positive regulation of multicellular organismal processGO:00512403870.035
nucleotide biosynthetic processGO:0009165980.035
cardiac muscle cell contractionGO:0086003100.035
regulation of rna biosynthetic processGO:20011413810.034
cell activationGO:0001775970.034
ribonucleoside metabolic processGO:00091191740.034
positive regulation of phosphorus metabolic processGO:00105622620.034
regulation of ion homeostasisGO:2000021630.033
behaviorGO:00076102050.033
organic acid metabolic processGO:00060822920.033
regulation of protein phosphorylationGO:00019321830.033
purine nucleotide biosynthetic processGO:0006164830.032
cellular response to nitrogen compoundGO:19016992100.032
regulation of programmed cell deathGO:00430673410.032
sensory perceptionGO:00076001010.032
response to molecule of bacterial originGO:00022371940.031
negative regulation of macromolecule metabolic processGO:00106052600.031
g protein coupled receptor signaling pathwayGO:00071862420.031
response to light stimulusGO:0009416520.031
carbohydrate derivative biosynthetic processGO:19011371240.031
negative regulation of signalingGO:00230571570.031
sequestering of metal ionGO:005123890.031
positive regulation of rna metabolic processGO:00512542030.030
positive regulation of secretion by cellGO:19035321280.030
response to other organismGO:00517072200.030
ribonucleotide catabolic processGO:00092611360.030
organonitrogen compound catabolic processGO:19015651790.030
single organism behaviorGO:00447081300.030
response to bacteriumGO:00096172000.030
response to ketoneGO:19016541820.030
peptide secretionGO:0002790860.030
intracellular transportGO:00469071850.029
macromolecular complex assemblyGO:00650032730.029
anterior posterior pattern specificationGO:000995210.029
response to ammonium ionGO:0060359710.029
regulation of fat cell differentiationGO:004559830.029
cyclic nucleotide metabolic processGO:0009187800.029
protein complex biogenesisGO:00702712630.029
regulation of protein modification processGO:00313991940.029
positive regulation of nitrogen compound metabolic processGO:00511733340.028
cellular catabolic processGO:00442482950.028
calcium ion transportGO:00068161310.028
regulation of homeostatic processGO:00328441010.028
localization of cellGO:00516742020.028
sequestering of calcium ionGO:005120880.028
cell communication involved in cardiac conductionGO:008606520.028
regulation of protein metabolic processGO:00512462890.027
regulation of cellular protein metabolic processGO:00322682670.027
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
apoptotic processGO:00069153810.027
protein phosphorylationGO:00064683450.027
negative regulation of transportGO:00510511360.027
cellular nitrogen compound catabolic processGO:00442701630.027
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.027
cellular component assemblyGO:00226073600.027
release of sequestered calcium ion into cytosolGO:0051209250.027
neuron differentiationGO:00301823680.027
programmed cell deathGO:00125013920.027
regulation of calcium ion transport into cytosolGO:0010522250.026
regulation of calcium ion transportGO:0051924770.026
negative regulation of cell deathGO:00605482290.026
regulation of system processGO:00440572080.026
response to ethanolGO:00454711620.026
potassium ion transportGO:0006813970.026
cellular response to organic cyclic compoundGO:00714072020.026
regulation of peptide secretionGO:0002791820.026
glycosyl compound metabolic processGO:19016571820.025
regulation of peptide transportGO:0090087870.025
neurological system processGO:00508772190.025
response to calcium ionGO:0051592590.025
positive regulation of nervous system developmentGO:00519621780.025
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314720.025
regulation of nucleotide metabolic processGO:00061401170.025
positive regulation of signal transductionGO:00099671750.025
response to alkaloidGO:00432791320.024
carboxylic acid metabolic processGO:00197522890.024
positive regulation of cell differentiationGO:00455972170.024
regulation of muscle system processGO:0090257790.024
regulation of cellular amine metabolic processGO:003323880.024
regulation of organelle organizationGO:0033043800.024
locomotory exploration behaviorGO:003564110.024
response to oxygen levelsGO:00704822650.024
regulation of secretion by cellGO:19035302080.024
protein homooligomerizationGO:0051260910.024
regulation of peptide hormone secretionGO:0090276800.024
nucleoside metabolic processGO:00091161790.023
cell type specific apoptotic processGO:00972851340.023
axis specificationGO:000979840.023
hormone mediated signaling pathwayGO:0009755230.023
positive regulation of cellular biosynthetic processGO:00313282950.023
purine containing compound biosynthetic processGO:0072522850.023
negative regulation of gene expressionGO:00106291990.023
second messenger mediated signalingGO:0019932510.023
Rat
metanephric comma shaped body morphogenesisGO:007227820.023
cellular response to peptide hormone stimulusGO:00713751200.023
hormone transportGO:00099141210.023
regulation of intracellular signal transductionGO:19025312180.022
multicellular organism reproductionGO:00325042330.022
monosaccharide metabolic processGO:0005996610.022
positive regulation of phosphorylationGO:00423271770.022
locomotionGO:00400112370.022
glucose metabolic processGO:0006006520.022
cardiac conductionGO:006133720.021
regulation of cellular amino acid metabolic processGO:000652120.021
positive regulation of nucleotide metabolic processGO:0045981910.021
learning or memoryGO:0007611900.021
transcription dna templatedGO:00063513770.021
maintenance of locationGO:0051235170.021
positive regulation of cell proliferationGO:00082842490.021
positive regulation of ion transportGO:0043270940.021
cyclic nucleotide biosynthetic processGO:0009190630.021
negative regulation of apoptotic processGO:00430661810.021
cellular component biogenesisGO:00440853680.021
positive regulation of transferase activityGO:0051347810.020
amine metabolic processGO:0009308380.020
reproductive structure developmentGO:00486081280.020
cellular response to endogenous stimulusGO:00714953770.020
regulation of cell proliferationGO:00421273590.020
cellular response to peptideGO:19016531330.020
leukocyte activationGO:0045321760.020
purine ribonucleotide metabolic processGO:00091502270.019
regulation of phosphorylationGO:00423252480.019
cellular response to cytokine stimulusGO:00713451270.019
ribonucleotide biosynthetic processGO:0009260850.019
sensory perception of light stimulusGO:005095330.019
actin mediated cell contractionGO:0070252120.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
regulation of growthGO:00400081050.019
glandular epithelial cell differentiationGO:000206740.019
cellular response to lipidGO:00713962010.019
cellular response to histamineGO:007142030.019
negative regulation of biosynthetic processGO:00098901680.019
cellular amine metabolic processGO:0044106380.019
eye morphogenesisGO:004859240.019
regulation of kinase activityGO:00435491170.018
cellular carbohydrate metabolic processGO:0044262720.018
purine ribonucleotide biosynthetic processGO:0009152810.018
regulation of blood circulationGO:19035221100.018
positive regulation of hormone secretionGO:0046887650.018
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.018
regulation of heart rateGO:0002027160.018
cell motilityGO:00488702020.018
positive regulation of peptide hormone secretionGO:0090277500.018
positive regulation of catalytic activityGO:00430851840.017
cellular response to growth factor stimulusGO:00713631620.017
secretion by cellGO:00329402480.017
positive regulation of secretionGO:00510471400.017
anatomical structure morphogenesisGO:00096532980.017
ribose phosphate biosynthetic processGO:0046390870.017
detection of visible lightGO:000958430.017
positive regulation of calcium ion transportGO:0051928360.017
cellular response to stressGO:00335542690.017
regulation of cellular ketone metabolic processGO:0010565270.017
positive regulation of heart contractionGO:0045823150.017
negative regulation of cell communicationGO:00106481580.017
response to hypoxiaGO:00016662310.017
positive regulation of gene expressionGO:00106282440.017
nucleoside triphosphate catabolic processGO:00091431230.017
regulation of cellular carbohydrate metabolic processGO:0010675390.017
neuron deathGO:00709971270.017
positive regulation of protein phosphorylationGO:00019341350.017
striated muscle contractionGO:0006941440.016
regulation of purine nucleotide metabolic processGO:19005421150.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
rhombomere developmentGO:002154610.016
sodium ion transmembrane transportGO:0035725670.016
response to peptideGO:19016522920.016
positive regulation of epithelial cell proliferationGO:0050679320.016
organic cyclic compound catabolic processGO:19013611750.016
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.016
organelle organizationGO:00069962660.016
hexose metabolic processGO:0019318580.016
negative regulation of neuron differentiationGO:0045665620.016
negative regulation of defecationGO:200029310.016
synaptic transmission glycinergicGO:006001220.016
regulation of purine nucleotide biosynthetic processGO:1900371460.015
regulation of nucleotide catabolic processGO:0030811650.015
l glutamate importGO:005193820.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
regulation of sequestering of calcium ionGO:0051282260.015
single organism membrane organizationGO:0044802740.015
hormone secretionGO:00468791150.015
positive regulation of cellular protein metabolic processGO:00322701670.015
regulation of carbohydrate metabolic processGO:0006109410.015
regulation of purine nucleotide catabolic processGO:0033121650.015
cellular protein localizationGO:00346131220.015
nucleobase containing compound catabolic processGO:00346551520.015
regulation of immune responseGO:0050776550.015
exploration behaviorGO:003564010.015
gonad developmentGO:00084061040.015
negative regulation of luteinizing hormone secretionGO:003368540.015
multicellular organism growthGO:003526410.015
regulation of cardiac muscle cell contractionGO:0086004110.014
insulin secretionGO:0030073690.014
single organism intracellular transportGO:19025821660.014
positive regulation of cellular amine metabolic processGO:003324030.014
regulation of cellular catabolic processGO:00313291010.014
cellular amino acid metabolic processGO:00065201070.014
camera type eye morphogenesisGO:004859320.014
negative regulation of metabolic processGO:00098923310.014
cytosolic calcium ion transportGO:0060401390.014
purine ribonucleoside catabolic processGO:00461301240.014
regulation of sensory perception of painGO:0051930290.014
regulation of response to woundingGO:1903034690.014
eating behaviorGO:0042755210.014
kidney developmentGO:0001822670.014
mapk cascadeGO:00001651400.014
cellular ketone metabolic processGO:0042180510.014
ras protein signal transductionGO:0007265290.014
regulation of synaptic transmissionGO:00508041410.014
gastric motilityGO:003548230.014
motor neuron axon guidanceGO:000804510.014
purine nucleoside metabolic processGO:00422781690.014
positive regulation of purine nucleotide biosynthetic processGO:1900373360.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
salivary gland developmentGO:000743130.014
response to monosaccharideGO:00342841590.013
cell part morphogenesisGO:00329901230.013
cytokine mediated signaling pathwayGO:0019221430.013
cardiovascular system developmentGO:00723581340.013
small gtpase mediated signal transductionGO:0007264360.013
negative regulation of cell differentiationGO:0045596990.013
ribonucleotide metabolic processGO:00092592310.013
regulation of sensory perceptionGO:0051931290.013
purine ribonucleoside metabolic processGO:00461281680.013
cell growthGO:00160491040.013
purine nucleotide catabolic processGO:00061951360.013
negative regulation of cellular metabolic processGO:00313242810.013
regulation of interleukin 6 productionGO:0032675120.013
grooming behaviorGO:000762540.013
camp biosynthetic processGO:0006171470.013
nucleoside phosphate catabolic processGO:19012921400.013
sex differentiationGO:00075481130.013
positive regulation of serotonin secretionGO:001406410.013
fatty acid metabolic processGO:0006631990.013
regulation of lipid biosynthetic processGO:0046890380.013
regulation of saliva secretionGO:004687730.012
carbohydrate biosynthetic processGO:0016051420.012
cellular response to glucocorticoid stimulusGO:0071385680.012
negative regulation of molecular functionGO:00440921330.012
regulation of catabolic processGO:00098941130.012
positive regulation of homeostatic processGO:0032846490.012
steroid metabolic processGO:0008202730.012
hormone metabolic processGO:0042445690.012
regulation of cell differentiationGO:00455953200.012
regulation of release of sequestered calcium ion into cytosolGO:0051279180.012
organic substance catabolic processGO:19015753160.012
regulation of apoptotic processGO:00429813350.012
ribonucleoside catabolic processGO:00424541260.012
negative regulation of programmed cell deathGO:00430691830.012
negative regulation of signal transductionGO:0009968830.012
s shaped body morphogenesisGO:007205020.012
cell adhesionGO:00071551100.012
positive regulation of neuron differentiationGO:00456661260.012
erk1 and erk2 cascadeGO:0070371480.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
visual perceptionGO:000760130.012
vesicle mediated transportGO:00161921810.012
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.012
developmental growth involved in morphogenesisGO:0060560330.012
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.012
biological adhesionGO:00226101100.012
cytoplasmic transportGO:00164821150.012
regulation of cell motilityGO:20001451310.012
regulation of neurogenesisGO:00507672470.011
regulation of ossificationGO:0030278320.011
myeloid leukocyte mediated immunityGO:0002444120.011
tube developmentGO:0035295890.011
protein homotetramerizationGO:0051289250.011
actin cytoskeleton organizationGO:0030036730.011
regulation of immune system processGO:00026821230.011
multicellular organismal water homeostasisGO:005089140.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
cell cycleGO:00070491010.011
metanephric part of ureteric bud developmentGO:003550210.011
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.011
telencephalon developmentGO:0021537620.011
regulation of neuron deathGO:19012141150.011
positive regulation of saliva secretionGO:004687830.011
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.011
proteolysisGO:00065081750.011
cellular response to steroid hormone stimulusGO:0071383930.011
carbohydrate catabolic processGO:0016052400.011
organelle localizationGO:0051640550.011
purine ribonucleotide catabolic processGO:00091541360.011
positive regulation of rna biosynthetic processGO:19026801970.011
cardiac muscle contractionGO:0060048270.011
actin filament based movementGO:0030048160.011
response to blue lightGO:000963710.011
defense responseGO:00069521940.011
positive regulation of cytokine productionGO:0001819420.011
response to testosteroneGO:0033574550.011
metanephric s shaped body morphogenesisGO:007228420.011
regulation of response to stressGO:00801341260.011
regulation of insulin secretionGO:0050796650.011
positive regulation of mapk cascadeGO:0043410920.010
negative regulation of cell developmentGO:0010721820.010
enzyme linked receptor protein signaling pathwayGO:00071671160.010
carbohydrate derivative catabolic processGO:19011361470.010
positive regulation of insulin secretionGO:0032024360.010
regulation of defecationGO:200029210.010
lipid metabolic processGO:00066292830.010
negative regulation of response to stimulusGO:00485851550.010
positive regulation of synaptic vesicle exocytosisGO:200030230.010
leukocyte proliferationGO:0070661290.010
developmental process involved in reproductionGO:00030061590.010
cellular response to corticosteroid stimulusGO:0071384690.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
purine containing compound catabolic processGO:00725231380.010
response to insulinGO:00328681330.010
positive regulation of protein kinase activityGO:0045860730.010
response to cgmpGO:007030530.010
purine ribonucleoside triphosphate metabolic processGO:00092051400.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
glycosyl compound catabolic processGO:19016581260.010
rho protein signal transductionGO:0007266110.010

Pde1c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.037
nervous system diseaseDOID:86300.018
eye and adnexa diseaseDOID:149200.018
retinal diseaseDOID:567900.018
disease of anatomical entityDOID:700.018
sensory system diseaseDOID:005015500.018
eye diseaseDOID:561400.018
inherited metabolic disorderDOID:65500.011