IMP: Integrative Multi-species Prediction

Rattus norvegicus

12 known processes

Ugt1a3

UDP glycosyltransferase 1 family, polypeptide A3

(Aliases: UDPGT 1-3,Ugt1,Ugt1a4)

Entrez: 396551
RGD: 1549728
UniProtKB: Q6T5F1

Process Predictions
Disease Predictions

Ugt1a3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
biphenyl catabolic process	GO:0070980	2	0.719	Rat
4 chlorobiphenyl metabolic process	GO:0018880	1	0.596	Rat
estrogen catabolic process	GO:0006711	1	0.540	Rat
organic acid metabolic process	GO:0006082	292	0.420	Mouse
oxoacid metabolic process	GO:0043436	290	0.395	Mouse
coumarin catabolic process	GO:0046226	3	0.375	Rat
response to nutrient	GO:0007584	248	0.308	Rat
lipid metabolic process	GO:0006629	283	0.296	Rat
monocarboxylic acid metabolic process	GO:0032787	152	0.295	Mouse
halogenated hydrocarbon metabolic process	GO:0042197	4	0.254	Rat
phenylpropanoid catabolic process	GO:0046271	3	0.252	Rat
single organism biosynthetic process	GO:0044711	342	0.240
cellular response to endogenous stimulus	GO:0071495	377	0.230	Rat
cellular hormone metabolic process	GO:0034754	49	0.209	Rat
cellular response to testosterone stimulus	GO:0071394	5	0.203	Rat
cellular lipid metabolic process	GO:0044255	208	0.196
response to peptide	GO:1901652	292	0.192	Rat
hormone metabolic process	GO:0042445	69	0.184	Rat
benzene containing compound metabolic process	GO:0042537	22	0.180	Rat
cellular response to hormone stimulus	GO:0032870	247	0.164	Rat
steroid metabolic process	GO:0008202	73	0.139	Rat
carboxylic acid metabolic process	GO:0019752	289	0.132	Mouse
cellular response to lipid	GO:0071396	201	0.116	Rat
response to peptide hormone	GO:0043434	278	0.113	Rat
response to nutrient levels	GO:0031667	370	0.111	Rat
biphenyl metabolic process	GO:0018879	10	0.109	Rat
response to molecule of bacterial origin	GO:0002237	194	0.102	Rat
cellular response to peptide	GO:1901653	133	0.094	Rat
catabolic process	GO:0009056	351	0.093	Rat
organic acid biosynthetic process	GO:0016053	83	0.093
cellular amino acid metabolic process	GO:0006520	107	0.093
response to extracellular stimulus	GO:0009991	380	0.086	Rat
single organism reproductive process	GO:0044702	297	0.085
response to biotic stimulus	GO:0009607	226	0.080	Rat
steroid catabolic process	GO:0006706	5	0.080	Rat
cellular response to oxygen containing compound	GO:1901701	386	0.077	Rat
lipid biosynthetic process	GO:0008610	128	0.076
response to insulin	GO:0032868	133	0.074
xenobiotic catabolic process	GO:0042178	7	0.073	Rat
cellular response to ketone	GO:1901655	51	0.073	Rat
response to glucocorticoid	GO:0051384	223	0.072	Rat
cellular ketone metabolic process	GO:0042180	51	0.072
cellular catabolic process	GO:0044248	295	0.069	Rat
carbohydrate derivative metabolic process	GO:1901135	346	0.068
hormone catabolic process	GO:0042447	2	0.068	Rat
liver development	GO:0001889	90	0.063	Rat
cellular response to xenobiotic stimulus	GO:0071466	19	0.063	Rat
response to ketone	GO:1901654	182	0.060	Rat
response to inorganic substance	GO:0010035	377	0.058
cellular response to steroid hormone stimulus	GO:0071383	93	0.057	Rat
response to xenobiotic stimulus	GO:0009410	23	0.056	Rat
carbohydrate metabolic process	GO:0005975	130	0.056	Mouse
single organism catabolic process	GO:0044712	283	0.055	Rat
cellular response to organic cyclic compound	GO:0071407	202	0.054	Rat
behavior	GO:0007610	205	0.052	Fly
cellular response to peptide hormone stimulus	GO:0071375	120	0.051	Rat
cellular response to organonitrogen compound	GO:0071417	197	0.051	Rat
reproduction	GO:0000003	245	0.050
response to ethanol	GO:0045471	162	0.048	Rat
organic substance catabolic process	GO:1901575	316	0.048	Rat
chlorinated hydrocarbon metabolic process	GO:0042196	4	0.047	Rat
carboxylic acid biosynthetic process	GO:0046394	83	0.047
regulation of hormone levels	GO:0010817	187	0.046	Rat
cellular response to nitrogen compound	GO:1901699	210	0.046	Rat
reproductive process	GO:0022414	372	0.045
multicellular organism reproduction	GO:0032504	233	0.045
response to corticosteroid	GO:0031960	235	0.044	Rat
phenylpropanoid metabolic process	GO:0009698	5	0.042	Rat
estrogen metabolic process	GO:0008210	11	0.042	Rat
single organism carbohydrate metabolic process	GO:0044723	118	0.041	Mouse
inflammatory response	GO:0006954	150	0.040	Rat
organophosphate metabolic process	GO:0019637	370	0.040
organonitrogen compound biosynthetic process	GO:1901566	167	0.040
response to other organism	GO:0051707	220	0.038	Rat
regulation of cellular ketone metabolic process	GO:0010565	27	0.038
multi organism reproductive process	GO:0044703	262	0.037
response to bacterium	GO:0009617	200	0.037	Rat
cellular response to corticosteroid stimulus	GO:0071384	69	0.036	Rat
regulation of cell differentiation	GO:0045595	320	0.034
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.034
cellular response to ethanol	GO:0071361	13	0.034	Rat
oxidation reduction process	GO:0055114	304	0.033
cellular response to insulin stimulus	GO:0032869	81	0.033
response to vitamin	GO:0033273	131	0.033
localization of cell	GO:0051674	202	0.033
steroid biosynthetic process	GO:0006694	48	0.033
ribonucleotide metabolic process	GO:0009259	231	0.032
organic cyclic compound catabolic process	GO:1901361	175	0.032	Rat
aromatic compound catabolic process	GO:0019439	168	0.032	Rat
regulation of cellular amino acid metabolic process	GO:0006521	2	0.032
negative regulation of cellular metabolic process	GO:0031324	281	0.032
rhythmic process	GO:0048511	156	0.032
nucleobase containing small molecule metabolic process	GO:0055086	316	0.032
positive regulation of phosphorus metabolic process	GO:0010562	262	0.031
gland development	GO:0048732	155	0.031	Rat
cellular response to alcohol	GO:0097306	87	0.030	Rat
cellular response to glucocorticoid stimulus	GO:0071385	68	0.030	Rat
cell migration	GO:0016477	197	0.030
nucleotide metabolic process	GO:0009117	279	0.030
fatty acid metabolic process	GO:0006631	99	0.029
central nervous system development	GO:0007417	311	0.029
regulation of lipid biosynthetic process	GO:0046890	38	0.028
regulation of phosphorus metabolic process	GO:0051174	349	0.028
small molecule biosynthetic process	GO:0044283	124	0.028
multicellular organismal reproductive process	GO:0048609	233	0.028
monosaccharide metabolic process	GO:0005996	61	0.028	Mouse
response to metal ion	GO:0010038	253	0.028
regeneration	GO:0031099	163	0.027
xenobiotic metabolic process	GO:0006805	19	0.027	Rat
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.027
response to herbicide	GO:0009635	16	0.027
response to testosterone	GO:0033574	55	0.026	Rat
response to acid chemical	GO:0001101	222	0.026
coenzyme metabolic process	GO:0006732	86	0.026
regulation of phosphorylation	GO:0042325	248	0.026
hepaticobiliary system development	GO:0061008	90	0.026	Rat
positive regulation of catalytic activity	GO:0043085	184	0.026
sensory perception	GO:0007600	101	0.026	Rat Fly
positive regulation of cellular amine metabolic process	GO:0033240	3	0.025
response to retinoic acid	GO:0032526	63	0.025
negative regulation of cell death	GO:0060548	229	0.025
positive regulation of multicellular organismal process	GO:0051240	387	0.025
purine ribonucleotide metabolic process	GO:0009150	227	0.025
neuron differentiation	GO:0030182	368	0.025
amine metabolic process	GO:0009308	38	0.025
regulation of cellular amine metabolic process	GO:0033238	8	0.025
anatomical structure morphogenesis	GO:0009653	298	0.025
purine nucleotide metabolic process	GO:0006163	229	0.025
cellular amine metabolic process	GO:0044106	38	0.025
secondary metabolic process	GO:0019748	15	0.024	Rat
positive regulation of signaling	GO:0023056	270	0.024
regulation of lipid metabolic process	GO:0019216	68	0.024
vesicle mediated transport	GO:0016192	181	0.024
peptidyl amino acid modification	GO:0018193	126	0.022
organic hydroxy compound metabolic process	GO:1901615	115	0.022
axis specification	GO:0009798	4	0.022
negative regulation of apoptotic process	GO:0043066	181	0.022
cation transport	GO:0006812	382	0.022
regulation of protein localization	GO:0032880	81	0.022
response to amino acid	GO:0043200	75	0.021
neurological system process	GO:0050877	219	0.021	Rat Fly
regulation of cell proliferation	GO:0042127	359	0.021
negative regulation of macromolecule metabolic process	GO:0010605	260	0.021
cellular component assembly	GO:0022607	360	0.021
response to oxygen levels	GO:0070482	265	0.021
response to external biotic stimulus	GO:0043207	221	0.021	Rat
spermatogenesis	GO:0007283	99	0.021
defense response	GO:0006952	194	0.021	Rat
blood circulation	GO:0008015	183	0.021
regulation of transferase activity	GO:0051338	123	0.020
organ regeneration	GO:0031100	101	0.020
g protein coupled receptor signaling pathway	GO:0007186	242	0.020
gamete generation	GO:0007276	124	0.020
response to toxic substance	GO:0009636	133	0.020
protein phosphorylation	GO:0006468	345	0.020
aging	GO:0007568	241	0.020
response to growth factor	GO:0070848	189	0.020
cellular calcium ion homeostasis	GO:0006874	160	0.020
response to starvation	GO:0042594	59	0.020	Rat
intracellular transport	GO:0046907	185	0.019
positive regulation of biosynthetic process	GO:0009891	319	0.019
chemical homeostasis	GO:0048878	292	0.019
terpenoid metabolic process	GO:0006721	37	0.019
positive regulation of cellular biosynthetic process	GO:0031328	295	0.019
synaptic transmission	GO:0007268	235	0.019
cellular component movement	GO:0006928	248	0.019
negative regulation of innate immune response	GO:0045824	4	0.019
rna biosynthetic process	GO:0032774	380	0.019
response to oxidative stress	GO:0006979	186	0.019
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.019
isoprenoid metabolic process	GO:0006720	45	0.018
positive regulation of developmental process	GO:0051094	283	0.018
intracellular signal transduction	GO:0035556	314	0.018
reproductive structure development	GO:0048608	128	0.018
positive regulation of protein modification process	GO:0031401	142	0.018
acute inflammatory response	GO:0002526	58	0.018	Rat
sexual reproduction	GO:0019953	148	0.018
acute phase response	GO:0006953	20	0.018	Rat
regulation of phosphate metabolic process	GO:0019220	349	0.018
response to purine containing compound	GO:0014074	126	0.018
regulation of molecular function	GO:0065009	398	0.018
response to organophosphorus	GO:0046683	102	0.018
regulation of multicellular organismal development	GO:2000026	376	0.018
response to decreased oxygen levels	GO:0036293	237	0.017
acrosome assembly	GO:0001675	3	0.017
peptidyl tyrosine modification	GO:0018212	72	0.017
carbohydrate derivative biosynthetic process	GO:1901137	124	0.017
regulation of apoptotic process	GO:0042981	335	0.017
lipid catabolic process	GO:0016042	46	0.017	Rat
cellular response to growth factor stimulus	GO:0071363	162	0.017
organophosphate biosynthetic process	GO:0090407	143	0.017
negative regulation of protein metabolic process	GO:0051248	114	0.017
neuron development	GO:0048666	286	0.017
b cell differentiation	GO:0030183	2	0.017
regulation of cell migration	GO:0030334	128	0.017
positive regulation of phosphate metabolic process	GO:0045937	262	0.017
dicarboxylic acid metabolic process	GO:0043648	42	0.017
single organism intracellular transport	GO:1902582	166	0.017
ribose phosphate metabolic process	GO:0019693	235	0.017
alpha amino acid metabolic process	GO:1901605	71	0.017
positive regulation of response to stimulus	GO:0048584	285	0.017
alkaloid metabolic process	GO:0009820	3	0.016
response to cytokine	GO:0034097	215	0.016
developmental process involved in reproduction	GO:0003006	159	0.016
positive regulation of cell communication	GO:0010647	271	0.016
nucleoside phosphate metabolic process	GO:0006753	283	0.016
glycosyl compound metabolic process	GO:1901657	182	0.016
positive regulation of cell development	GO:0010720	176	0.015
monocarboxylic acid biosynthetic process	GO:0072330	48	0.015
cellular response to growth hormone stimulus	GO:0071378	6	0.015	Rat
metal ion homeostasis	GO:0055065	186	0.015
negative regulation of natural killer cell mediated cytotoxicity	GO:0045953	4	0.015
negative regulation of metabolic process	GO:0009892	331	0.015
regulation of programmed cell death	GO:0043067	341	0.015
negative regulation of cellular protein metabolic process	GO:0032269	106	0.015
anion transport	GO:0006820	178	0.015
male gamete generation	GO:0048232	99	0.015
purine ribonucleoside metabolic process	GO:0046128	168	0.015
homeostatic process	GO:0042592	331	0.015
embryonic skeletal system development	GO:0048706	3	0.015
response to increased oxygen levels	GO:0036296	45	0.015
response to hydrogen peroxide	GO:0042542	89	0.015
mitotic cell cycle process	GO:1903047	35	0.015
programmed cell death	GO:0012501	392	0.015
proteolysis	GO:0006508	175	0.015
positive regulation of molecular function	GO:0044093	230	0.014
cell cycle	GO:0007049	101	0.014
cell projection organization	GO:0030030	302	0.014
protein transport	GO:0015031	132	0.014
heterocycle catabolic process	GO:0046700	167	0.014	Rat
regulation of nervous system development	GO:0051960	264	0.014
fertilization	GO:0009566	3	0.014
response to estrogen	GO:0043627	232	0.014
positive regulation of phosphorylation	GO:0042327	177	0.014
negative regulation of programmed cell death	GO:0043069	183	0.014
regulation of protein kinase activity	GO:0045859	105	0.014
chemosensory behavior	GO:0007635	2	0.014
immune system process	GO:0002376	204	0.014
positive regulation of nervous system development	GO:0051962	178	0.014
response to dexamethasone	GO:0071548	49	0.014
leukocyte cell cell adhesion	GO:0007159	4	0.014
response to camp	GO:0051591	91	0.014
cellular component biogenesis	GO:0044085	368	0.014
apoptotic process	GO:0006915	381	0.014
nucleotide biosynthetic process	GO:0009165	98	0.013
circulatory system process	GO:0003013	183	0.013
regulation of cellular protein metabolic process	GO:0032268	267	0.013
regulation of kinase activity	GO:0043549	117	0.013
regulation of neuron differentiation	GO:0045664	208	0.013
cell motility	GO:0048870	202	0.013
response to reactive oxygen species	GO:0000302	120	0.013
divalent inorganic cation transport	GO:0072511	134	0.013
response to lipopolysaccharide	GO:0032496	191	0.013	Rat
regulation of anatomical structure morphogenesis	GO:0022603	141	0.013
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.013
regulation of neurogenesis	GO:0050767	247	0.013
heart morphogenesis	GO:0003007	3	0.013
female pregnancy	GO:0007565	122	0.013
peptide transport	GO:0015833	97	0.013
positive regulation of protein metabolic process	GO:0051247	178	0.013
cyclic nucleotide biosynthetic process	GO:0009190	63	0.013
regulation of nucleotide metabolic process	GO:0006140	117	0.013
cofactor metabolic process	GO:0051186	95	0.013
regulation of cellular localization	GO:0060341	263	0.013
regulation of cell motility	GO:2000145	131	0.012
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.012
response to hypoxia	GO:0001666	231	0.012
cellular component morphogenesis	GO:0032989	155	0.012
peptidyl tyrosine phosphorylation	GO:0018108	72	0.012
protein localization	GO:0008104	191	0.012
response to carbohydrate	GO:0009743	183	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012
macromolecular complex assembly	GO:0065003	273	0.012
nucleoside metabolic process	GO:0009116	179	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
negative regulation of rna metabolic process	GO:0051253	123	0.012
positive regulation of cell differentiation	GO:0045597	217	0.012
embryonic pattern specification	GO:0009880	1	0.012
cell cell signaling	GO:0007267	335	0.012
response to mechanical stimulus	GO:0009612	134	0.012
locomotion	GO:0040011	237	0.012
c21 steroid hormone metabolic process	GO:0008207	14	0.012
eye morphogenesis	GO:0048592	4	0.012
hormone biosynthetic process	GO:0042446	25	0.012
regulation of catalytic activity	GO:0050790	304	0.012
fatty acid oxidation	GO:0019395	29	0.012
transcription dna templated	GO:0006351	377	0.012
macromolecule localization	GO:0033036	252	0.012
negative regulation of molecular function	GO:0044092	133	0.011
response to cadmium ion	GO:0046686	35	0.011
drug catabolic process	GO:0042737	1	0.011
negative regulation of transcription dna templated	GO:0045892	116	0.011
ovulation cycle	GO:0042698	67	0.011
olfactory behavior	GO:0042048	2	0.011
regulation of natural killer cell mediated immune response to tumor cell	GO:0002855	1	0.011
cellular homeostasis	GO:0019725	252	0.011
cellular ion homeostasis	GO:0006873	184	0.011
response to vitamin d	GO:0033280	34	0.011
regulation of protein metabolic process	GO:0051246	289	0.011
mitotic spindle organization	GO:0007052	2	0.011
glycosaminoglycan biosynthetic process	GO:0006024	4	0.011
nucleoside phosphate biosynthetic process	GO:1901293	102	0.011
carboxylic acid transport	GO:0046942	115	0.011
neuron projection development	GO:0031175	273	0.011
ribonucleotide biosynthetic process	GO:0009260	85	0.011
regulation of metal ion transport	GO:0010959	118	0.011
calcium ion homeostasis	GO:0055074	162	0.011
cellular response to external stimulus	GO:0071496	118	0.011
positive regulation of nucleotide biosynthetic process	GO:0030810	36	0.011
nucleic acid templated transcription	GO:0097659	379	0.011
regulation of cell growth	GO:0001558	85	0.011
neuronal action potential	GO:0019228	35	0.011
regulation of cellular component organization	GO:0051128	368	0.011
cardiac chamber development	GO:0003205	1	0.011
purine containing compound metabolic process	GO:0072521	253	0.011
cellular response to stress	GO:0033554	269	0.011
regulation of ion transport	GO:0043269	245	0.011
phthalate metabolic process	GO:0018963	8	0.011
lipid storage	GO:0019915	1	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
alcohol metabolic process	GO:0006066	77	0.011
ribonucleoside metabolic process	GO:0009119	174	0.011
ossification	GO:0001503	70	0.011
chromosome segregation	GO:0007059	2	0.010
purine containing compound biosynthetic process	GO:0072522	85	0.010
regulation of establishment of protein localization	GO:0070201	69	0.010
ion homeostasis	GO:0050801	212	0.010
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.010
purine nucleotide biosynthetic process	GO:0006164	83	0.010
ribose phosphate biosynthetic process	GO:0046390	87	0.010
positive regulation of cellular component organization	GO:0051130	200	0.010
protein oligomerization	GO:0051259	191	0.010
positive regulation of nucleotide metabolic process	GO:0045981	91	0.010
kidney mesenchyme development	GO:0072074	2	0.010
reproductive system development	GO:0061458	128	0.010
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.010

Ugt1a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.021
inherited metabolic disorder	DOID:655	0.021
disease of anatomical entity	DOID:7	0.020
nervous system disease	DOID:863	0.020
cardiovascular system disease	DOID:1287	0.019
musculoskeletal system disease	DOID:17	0.010

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