Rattus norvegicus

31 known processes

Polr1a

polymerase (RNA) I polypeptide A

(Aliases: Rpa1,Rpo1-4)

Polr1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.120
response to extracellular stimulusGO:00099913800.120
gland developmentGO:00487321550.086
regulation of rna biosynthetic processGO:20011413810.086
regulation of cell proliferationGO:00421273590.083
nucleobase containing small molecule metabolic processGO:00550863160.081
nucleic acid templated transcriptionGO:00976593790.073
regulation of nucleic acid templated transcriptionGO:19035063800.072
carbohydrate derivative metabolic processGO:19011353460.072
carboxylic acid metabolic processGO:00197522890.070
transcription from rna polymerase ii promoterGO:00063662520.064
response to peptide hormoneGO:00434342780.062
reproductive processGO:00224143720.062
ribonucleotide metabolic processGO:00092592310.061
regulation of transcription dna templatedGO:00063553740.059
cellular response to endogenous stimulusGO:00714953770.058
regulation of apoptotic processGO:00429813350.058
rna biosynthetic processGO:00327743800.058
cellular amino acid metabolic processGO:00065201070.053
organophosphate metabolic processGO:00196373700.053
ribose phosphate metabolic processGO:00196932350.053
positive regulation of multicellular organismal processGO:00512403870.053
cellular component movementGO:00069282480.051
alpha amino acid metabolic processGO:1901605710.050
macromolecule localizationGO:00330362520.049
secretionGO:00469033070.049
positive regulation of nitrogen compound metabolic processGO:00511733340.049
purine ribonucleoside monophosphate metabolic processGO:0009167840.048
transcription dna templatedGO:00063513770.048
nucleoside phosphate metabolic processGO:00067532830.047
macromolecular complex assemblyGO:00650032730.047
organic substance catabolic processGO:19015753160.045
single organism reproductive processGO:00447022970.045
intracellular signal transductionGO:00355563140.045
oxoacid metabolic processGO:00434362900.044
cellular response to oxygen containing compoundGO:19017013860.044
multi organism reproductive processGO:00447032620.044
regulation of multicellular organismal developmentGO:20000263760.043
single organism biosynthetic processGO:00447113420.043
regulation of rna metabolic processGO:00512523910.043
cellular component biogenesisGO:00440853680.040
glycosyl compound metabolic processGO:19016571820.040
regulation of cell differentiationGO:00455953200.040
ribonucleotide biosynthetic processGO:0009260850.040
negative regulation of metabolic processGO:00098923310.039
response to growth factorGO:00708481890.039
negative regulation of macromolecule metabolic processGO:00106052600.038
cellular response to growth factor stimulusGO:00713631620.038
regulation of transcription from rna polymerase ii promoterGO:00063572340.037
organophosphate biosynthetic processGO:00904071430.037
macromolecular complex subunit organizationGO:00439333390.037
regulation of neurogenesisGO:00507672470.037
head developmentGO:00603222470.037
cell motilityGO:00488702020.037
response to nutrient levelsGO:00316673700.036
negative regulation of cell deathGO:00605482290.036
response to nutrientGO:00075842480.035
cellular component assemblyGO:00226073600.035
cellular catabolic processGO:00442482950.035
apoptotic processGO:00069153810.035
cell migrationGO:00164771970.034
cellular response to organonitrogen compoundGO:00714171970.034
organic acid metabolic processGO:00060822920.034
response to peptideGO:19016522920.034
regulation of cellular component organizationGO:00511283680.033
catabolic processGO:00090563510.033
response to purine containing compoundGO:00140741260.033
gliogenesisGO:0042063930.033
cellular response to stressGO:00335542690.033
regulation of cell developmentGO:00602842630.033
response to oxygen levelsGO:00704822650.033
brain developmentGO:00074202470.033
negative regulation of biosynthetic processGO:00098901680.033
positive regulation of gene expressionGO:00106282440.033
heart morphogenesisGO:000300730.032
organelle organizationGO:00069962660.032
regenerationGO:00310991630.032
regulation of cellular localizationGO:00603412630.032
response to inorganic substanceGO:00100353770.032
negative regulation of nitrogen compound metabolic processGO:00511721610.032
negative regulation of gene expressionGO:00106291990.031
single organism catabolic processGO:00447122830.031
localization of cellGO:00516742020.031
central nervous system developmentGO:00074173110.031
negative regulation of programmed cell deathGO:00430691830.031
positive regulation of cellular biosynthetic processGO:00313282950.031
purine nucleotide metabolic processGO:00061632290.031
negative regulation of cellular metabolic processGO:00313242810.031
regulation of programmed cell deathGO:00430673410.030
positive regulation of neurogenesisGO:00507691650.030
protein phosphorylationGO:00064683450.030
organonitrogen compound biosynthetic processGO:19015661670.030
positive regulation of biosynthetic processGO:00098913190.029
programmed cell deathGO:00125013920.029
locomotionGO:00400112370.029
nucleoside phosphate biosynthetic processGO:19012931020.029
regulation of cellular ketone metabolic processGO:0010565270.028
negative regulation of nucleic acid templated transcriptionGO:19035071170.028
homeostatic processGO:00425923310.028
cellular response to peptide hormone stimulusGO:00713751200.028
cellular response to nitrogen compoundGO:19016992100.027
nucleotide metabolic processGO:00091172790.027
negative regulation of transcription dna templatedGO:00458921160.026
protein complex assemblyGO:00064612630.026
negative regulation of signalingGO:00230571570.026
negative regulation of multicellular organismal processGO:00512412030.026
developmental process involved in reproductionGO:00030061590.026
cellular ketone metabolic processGO:0042180510.026
response to woundingGO:00096112540.026
positive regulation of developmental processGO:00510942830.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
intracellular transportGO:00469071850.025
negative regulation of rna biosynthetic processGO:19026791180.025
ribonucleoside metabolic processGO:00091191740.025
protein localizationGO:00081041910.025
protein complex biogenesisGO:00702712630.025
purine containing compound metabolic processGO:00725212530.025
carbohydrate derivative biosynthetic processGO:19011371240.025
response to decreased oxygen levelsGO:00362932370.025
reproductionGO:00000032450.025
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.025
response to organophosphorusGO:00466831020.025
response to corticosteroidGO:00319602350.024
positive regulation of cell differentiationGO:00455972170.024
negative regulation of apoptotic processGO:00430661810.024
positive regulation of molecular functionGO:00440932300.024
negative regulation of nucleobase containing compound metabolic processGO:00459341530.024
reproductive structure developmentGO:00486081280.024
positive regulation of response to stimulusGO:00485842850.024
purine ribonucleotide metabolic processGO:00091502270.023
immune system processGO:00023762040.023
regulation of phosphate metabolic processGO:00192203490.023
positive regulation of rna metabolic processGO:00512542030.023
nucleoside monophosphate metabolic processGO:0009123930.023
purine ribonucleoside metabolic processGO:00461281680.023
dna metabolic processGO:0006259960.023
regulation of cellular component movementGO:00512701500.023
regulation of intracellular signal transductionGO:19025312180.023
nucleoside metabolic processGO:00091161790.023
positive regulation of rna biosynthetic processGO:19026801970.023
response to metal ionGO:00100382530.023
positive regulation of transcription dna templatedGO:00458931970.023
single organism intracellular transportGO:19025821660.023
positive regulation of cell proliferationGO:00082842490.023
nucleotide biosynthetic processGO:0009165980.023
anatomical structure morphogenesisGO:00096532980.023
regulation of nervous system developmentGO:00519602640.022
growthGO:00400071650.022
protein targetingGO:0006605610.022
regulation of phosphorus metabolic processGO:00511743490.022
cellular response to hormone stimulusGO:00328702470.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
protein complex subunit organizationGO:00718223020.021
regulation of signal transductionGO:00099663180.021
regulation of body fluid levelsGO:0050878900.021
regulation of cellular protein metabolic processGO:00322682670.021
purine containing compound biosynthetic processGO:0072522850.021
response to hypoxiaGO:00016662310.021
multicellular organismal reproductive processGO:00486092330.021
glial cell differentiationGO:0010001650.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
ribonucleoside triphosphate metabolic processGO:00091991410.021
response to glucocorticoidGO:00513842230.021
cellular chemical homeostasisGO:00550822470.020
ribonucleoside monophosphate metabolic processGO:0009161880.020
purine nucleotide biosynthetic processGO:0006164830.020
purine nucleoside metabolic processGO:00422781690.020
amine metabolic processGO:0009308380.020
chemical homeostasisGO:00488782920.020
neuron differentiationGO:00301823680.020
regulation of cellular amino acid metabolic processGO:000652120.020
cellular homeostasisGO:00197252520.020
regulation of secretion by cellGO:19035302080.020
reproductive system developmentGO:00614581280.020
cellular amine metabolic processGO:0044106380.020
negative regulation of cell proliferationGO:00082851190.020
negative regulation of cell communicationGO:00106481580.019
regulation of phosphorylationGO:00423252480.019
response to cytokineGO:00340972150.019
nucleoside triphosphate metabolic processGO:00091411440.019
rhythmic processGO:00485111560.019
cation transportGO:00068123820.019
gamete generationGO:00072761240.018
liver developmentGO:0001889900.018
response to radiationGO:00093141370.018
response to estradiolGO:00323551640.018
vesicle mediated transportGO:00161921810.018
purine ribonucleotide biosynthetic processGO:0009152810.018
forebrain developmentGO:0030900980.018
agingGO:00075682410.018
cellular modified amino acid metabolic processGO:0006575610.018
response to insulinGO:00328681330.018
positive regulation of nervous system developmentGO:00519621780.018
single organism organelle organizationGO:19025891800.018
regulation of catalytic activityGO:00507903040.018
response to ketoneGO:19016541820.018
cellular response to peptideGO:19016531330.018
negative regulation of developmental processGO:00510931250.018
response to oxidative stressGO:00069791860.017
positive regulation of cellular amine metabolic processGO:003324030.017
ribose phosphate biosynthetic processGO:0046390870.017
embryonic pattern specificationGO:000988010.017
inflammatory responseGO:00069541500.017
positive regulation of cell developmentGO:00107201760.017
cell type specific apoptotic processGO:00972851340.017
neurological system processGO:00508772190.017
positive regulation of programmed cell deathGO:00430681570.017
urogenital system developmentGO:0001655780.017
response to bacteriumGO:00096172000.017
protein oligomerizationGO:00512591910.017
regulation of membrane potentialGO:00423911100.017
positive regulation of phosphorus metabolic processGO:00105622620.017
positive regulation of phosphate metabolic processGO:00459372620.017
aromatic compound catabolic processGO:00194391680.017
anterior posterior pattern specificationGO:000995210.016
cellular macromolecule localizationGO:00707271220.016
regulation of molecular functionGO:00650093980.016
establishment of protein localizationGO:00451841410.016
positive regulation of cell deathGO:00109421840.016
nitrogen compound transportGO:00717052290.016
cellular amino acid biosynthetic processGO:0008652320.016
cellular response to insulin stimulusGO:0032869810.016
purine nucleoside monophosphate metabolic processGO:0009126840.016
positive regulation of protein metabolic processGO:00512471780.016
cellular protein localizationGO:00346131220.015
microtubule organizing center organizationGO:003102310.015
cytoplasmic transportGO:00164821150.015
response to lipopolysaccharideGO:00324961910.015
response to external biotic stimulusGO:00432072210.015
leukocyte activationGO:0045321760.015
hormone transportGO:00099141210.015
regulation of neuron differentiationGO:00456642080.015
neuron developmentGO:00486662860.015
positive regulation of transportGO:00510502450.015
female pregnancyGO:00075651220.015
regulation of mapk cascadeGO:00434081160.015
regulation of anatomical structure morphogenesisGO:00226031410.015
cellular response to cytokine stimulusGO:00713451270.015
heterocycle catabolic processGO:00467001670.015
regulation of protein modification processGO:00313991940.015
nucleobase containing compound catabolic processGO:00346551520.015
multicellular organism reproductionGO:00325042330.015
negative regulation of response to stimulusGO:00485851550.015
cell fate determinationGO:000170920.015
response to reactive oxygen speciesGO:00003021200.015
cell growthGO:00160491040.015
response to acid chemicalGO:00011012220.015
gastrulationGO:000736920.015
positive regulation of signalingGO:00230562700.014
axis specificationGO:000979840.014
protein transportGO:00150311320.014
regulation of protein phosphorylationGO:00019321830.014
cardiac chamber developmentGO:000320510.014
eye morphogenesisGO:004859240.014
secretion by tissueGO:0032941370.014
chromosome segregationGO:000705920.014
response to vitaminGO:00332731310.014
purine containing compound catabolic processGO:00725231380.014
hepaticobiliary system developmentGO:0061008900.014
response to toxic substanceGO:00096361330.014
ras protein signal transductionGO:0007265290.014
developmental growthGO:00485891000.014
tube developmentGO:0035295890.014
response to estrogenGO:00436272320.014
blood circulationGO:00080151830.014
negative regulation of cellular biosynthetic processGO:00313271610.014
intracellular protein transportGO:0006886790.014
regulation of protein transportGO:0051223680.014
organonitrogen compound catabolic processGO:19015651790.014
response to molecule of bacterial originGO:00022371940.014
organ regenerationGO:00311001010.014
positive regulation of intracellular signal transductionGO:19025331380.014
regulation of mesenchymal cell proliferationGO:001046440.013
positive regulation of cellular protein metabolic processGO:00322701670.013
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
single organism cellular localizationGO:19025801020.013
regulation of cellular amine metabolic processGO:003323880.013
negative regulation of cell developmentGO:0010721820.013
negative regulation of transportGO:00510511360.013
secretion by cellGO:00329402480.013
organic cyclic compound catabolic processGO:19013611750.013
response to biotic stimulusGO:00096072260.013
negative regulation of neurogenesisGO:0050768780.013
renal system developmentGO:0072001670.013
response to carbohydrateGO:00097431830.013
negative regulation of cell cycle phase transitionGO:190198840.013
small molecule biosynthetic processGO:00442831240.013
centrosome organizationGO:005129710.013
organophosphate catabolic processGO:00464341480.013
cellular response to lipidGO:00713962010.013
embryonic skeletal system developmentGO:004870630.013
regulation of protein metabolic processGO:00512462890.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
response to campGO:0051591910.013
amide transportGO:00428861050.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
mapk cascadeGO:00001651400.013
negative regulation of signal transductionGO:0009968830.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
regulation of dna metabolic processGO:0051052600.013
cell projection organizationGO:00300303020.013
positive regulation of signal transductionGO:00099671750.013
neuron projection developmentGO:00311752730.012
cellular response to oxidative stressGO:0034599760.012
small gtpase mediated signal transductionGO:0007264360.012
tissue developmentGO:00098882520.012
positive regulation of protein phosphorylationGO:00019341350.012
epithelium developmentGO:0060429960.012
glycosyl compound catabolic processGO:19016581260.012
regulation of cell migrationGO:00303341280.012
cell activationGO:0001775970.012
response to transition metal nanoparticleGO:19902671220.012
positive regulation of cell communicationGO:00106472710.012
sexual reproductionGO:00199531480.012
regulation of locomotionGO:00400121480.012
response to glucoseGO:00097491360.012
cation transmembrane transportGO:00986552630.012
transmembrane transportGO:00550854120.012
cellular response to reactive oxygen speciesGO:0034614550.012
circulatory system developmentGO:00723591340.012
multicellular organismal signalingGO:0035637440.012
b cell differentiationGO:003018320.012
response to monosaccharideGO:00342841590.012
peptidyl amino acid modificationGO:00181931260.012
ribonucleoside catabolic processGO:00424541260.012
synaptic growth at neuromuscular junctionGO:005112410.011
positive regulation of apoptotic processGO:00430651540.011
cellular ion homeostasisGO:00068731840.011
response to other organismGO:00517072200.011
mitochondrion organizationGO:0007005350.011
organic acid biosynthetic processGO:0016053830.011
regulation of protein kinase activityGO:00458591050.011
neuronal action potentialGO:0019228350.011
regulation of establishment of protein localizationGO:0070201690.011
cellular lipid metabolic processGO:00442552080.011
regulation of hormone levelsGO:00108171870.011
response to alkaloidGO:00432791320.011
positive regulation of protein modification processGO:00314011420.011
peptide transportGO:0015833970.011
carboxylic acid biosynthetic processGO:0046394830.011
circulatory system processGO:00030131830.011
metal ion transportGO:00300012890.011
kidney developmentGO:0001822670.011
response to mechanical stimulusGO:00096121340.011
negative regulation of molecular functionGO:00440921330.011
appendage morphogenesisGO:003510740.011
signal releaseGO:00230611450.011
cardiovascular system developmentGO:00723581340.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
cell adhesionGO:00071551100.011
ribonucleotide catabolic processGO:00092611360.011
nuclear transportGO:0051169490.011
lipid storageGO:001991510.011
nucleoside monophosphate biosynthetic processGO:0009124280.011
calcium ion homeostasisGO:00550741620.011
purine nucleoside monophosphate biosynthetic processGO:0009127200.011
adult locomotory behaviorGO:000834440.011
regulation of nucleotide metabolic processGO:00061401170.010
multicellular organism growthGO:003526410.010
nucleoside triphosphate catabolic processGO:00091431230.010
biological adhesionGO:00226101100.010
proteolysisGO:00065081750.010
cellular component morphogenesisGO:00329891550.010
nucleobase biosynthetic processGO:004611220.010
positive regulation of neuron differentiationGO:00456661260.010
cellular response to organic cyclic compoundGO:00714072020.010
negative regulation of rna metabolic processGO:00512531230.010
response to hexoseGO:00097461440.010
cell cell signalingGO:00072673350.010
camera type eye morphogenesisGO:004859320.010
multi multicellular organism processGO:00447061380.010
nucleotide catabolic processGO:00091661390.010
cellular nitrogen compound catabolic processGO:00442701630.010
ion homeostasisGO:00508012120.010
spermatogenesisGO:0007283990.010
negative regulation of neuron differentiationGO:0045665620.010
chromosome organizationGO:0051276360.010
metal ion homeostasisGO:00550651860.010
nucleoside phosphate catabolic processGO:19012921400.010
positive regulation of catalytic activityGO:00430851840.010
regulation of anatomical structure sizeGO:00900661350.010
anatomical structure formation involved in morphogenesisGO:0048646830.010

Polr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.024
disease of anatomical entityDOID:700.024
musculoskeletal system diseaseDOID:1700.016
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
disease of metabolismDOID:001466700.012
organ system cancerDOID:005068600.012
central nervous system diseaseDOID:33100.011