Rattus norvegicus

0 known processes

Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

(Aliases: MGC95161)

Smpdl3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442552080.170
Rat
monocarboxylic acid metabolic processGO:00327871520.160
response to external biotic stimulusGO:00432072210.148
carbohydrate derivative metabolic processGO:19011353460.147
lipid metabolic processGO:00066292830.141
Rat
fatty acid metabolic processGO:0006631990.120
organic substance catabolic processGO:19015753160.092
organic acid metabolic processGO:00060822920.091
inflammatory responseGO:00069541500.089
defense responseGO:00069521940.087
response to lipopolysaccharideGO:00324961910.087
single organism catabolic processGO:00447122830.083
response to other organismGO:00517072200.069
response to biotic stimulusGO:00096072260.067
regulation of cell proliferationGO:00421273590.059
secretionGO:00469033070.059
response to inorganic substanceGO:00100353770.058
response to bacteriumGO:00096172000.055
oxoacid metabolic processGO:00434362900.055
regulation of cellular component organizationGO:00511283680.053
anatomical structure morphogenesisGO:00096532980.053
carboxylic acid metabolic processGO:00197522890.052
secretion by cellGO:00329402480.051
response to molecule of bacterial originGO:00022371940.050
immune responseGO:00069551040.050
apoptotic processGO:00069153810.050
Rat
response to extracellular stimulusGO:00099913800.049
regulation of secretion by cellGO:19035302080.049
programmed cell deathGO:00125013920.048
Rat
hormone secretionGO:00468791150.048
activation of immune responseGO:0002253260.047
fatty acid derivative metabolic processGO:1901568380.047
regulation of hydrolase activityGO:00513361430.047
cellular response to lipidGO:00713962010.043
cofactor metabolic processGO:0051186950.043
regulation of protein metabolic processGO:00512462890.043
positive regulation of cell deathGO:00109421840.043
Rat
positive regulation of cell proliferationGO:00082842490.041
positive regulation of response to stimulusGO:00485842850.041
catabolic processGO:00090563510.040
monocarboxylic acid catabolic processGO:0072329280.040
response to metal ionGO:00100382530.039
regulation of catalytic activityGO:00507903040.039
carbohydrate metabolic processGO:00059751300.039
chemical homeostasisGO:00488782920.038
cell cell signalingGO:00072673350.037
response to peptide hormoneGO:00434342780.037
positive regulation of immune system processGO:0002684900.036
response to peptideGO:19016522920.036
positive regulation of signalingGO:00230562700.035
regulation of response to stressGO:00801341260.035
cellular ketone metabolic processGO:0042180510.034
regulation of cellular localizationGO:00603412630.034
regulation of multicellular organismal developmentGO:20000263760.033
positive regulation of multicellular organismal processGO:00512403870.033
ion homeostasisGO:00508012120.032
oxidation reduction processGO:00551143040.032
organophosphate metabolic processGO:00196373700.032
response to oxidative stressGO:00069791860.031
protein oligomerizationGO:00512591910.031
lipid catabolic processGO:0016042460.030
hormone transportGO:00099141210.030
response to transition metal nanoparticleGO:19902671220.030
intracellular signal transductionGO:00355563140.030
single organism biosynthetic processGO:00447113420.029
Rat
organonitrogen compound catabolic processGO:19015651790.029
leukocyte mediated immunityGO:0002443280.028
response to ethanolGO:00454711620.028
response to glucocorticoidGO:00513842230.027
positive regulation of developmental processGO:00510942830.027
regulation of hormone levelsGO:00108171870.027
lipid modificationGO:0030258520.026
nucleobase containing small molecule metabolic processGO:00550863160.026
nucleoside phosphate metabolic processGO:00067532830.026
organic acid catabolic processGO:0016054490.026
regulation of rna metabolic processGO:00512523910.026
fatty acid beta oxidationGO:0006635220.025
cellular catabolic processGO:00442482950.025
anion transportGO:00068201780.024
hexose metabolic processGO:0019318580.024
carboxylic acid catabolic processGO:0046395490.024
response to oxygen levelsGO:00704822650.024
regulation of programmed cell deathGO:00430673410.024
Rat
nucleotide metabolic processGO:00091172790.023
regulation of neurogenesisGO:00507672470.023
positive regulation of apoptotic processGO:00430651540.023
Rat
negative regulation of metabolic processGO:00098923310.023
single organism carbohydrate metabolic processGO:00447231180.023
homeostatic processGO:00425923310.023
response to decreased oxygen levelsGO:00362932370.023
positive regulation of protein metabolic processGO:00512471780.022
regulation of cell differentiationGO:00455953200.022
purine nucleoside metabolic processGO:00422781690.022
protein complex assemblyGO:00064612630.022
reproductive processGO:00224143720.021
regulation of signal transductionGO:00099663180.021
purine containing compound metabolic processGO:00725212530.021
positive regulation of cell communicationGO:00106472710.021
heterocycle catabolic processGO:00467001670.021
tissue developmentGO:00098882520.021
amide transportGO:00428861050.020
insulin secretionGO:0030073690.020
response to nutrient levelsGO:00316673700.020
multicellular organismal reproductive processGO:00486092330.020
carboxylic acid biosynthetic processGO:0046394830.020
cellular response to biotic stimulusGO:0071216590.020
regulation of molecular functionGO:00650093980.020
reproductive system developmentGO:00614581280.020
cellular component assemblyGO:00226073600.020
multicellular organism reproductionGO:00325042330.020
regulation of cell developmentGO:00602842630.019
nitrogen compound transportGO:00717052290.019
lipid oxidationGO:0034440300.019
cellular homeostasisGO:00197252520.019
amine metabolic processGO:0009308380.019
response to temperature stimulusGO:0009266940.019
ribonucleoside metabolic processGO:00091191740.019
multi multicellular organism processGO:00447061380.019
central nervous system developmentGO:00074173110.019
peptide secretionGO:0002790860.019
regulation of peptide transportGO:0090087870.019
signal releaseGO:00230611450.018
immune effector processGO:0002252530.018
positive regulation of programmed cell deathGO:00430681570.018
Rat
cellular amine metabolic processGO:0044106380.018
growthGO:00400071650.018
organic cyclic compound catabolic processGO:19013611750.018
nucleotide catabolic processGO:00091661390.017
ribose phosphate metabolic processGO:00196932350.017
response to nutrientGO:00075842480.017
aromatic compound catabolic processGO:00194391680.017
regulation of insulin secretionGO:0050796650.017
regulation of defense responseGO:0031347680.017
gonad developmentGO:00084061040.017
protein complex biogenesisGO:00702712630.017
positive regulation of molecular functionGO:00440932300.017
calcium ion homeostasisGO:00550741620.017
circulatory system developmentGO:00723591340.017
regulation of cellular ketone metabolic processGO:0010565270.017
regulation of immune responseGO:0050776550.017
carnitine metabolic processGO:000943730.017
cellular chemical homeostasisGO:00550822470.017
cellular cation homeostasisGO:00300031800.017
cellular response to organic cyclic compoundGO:00714072020.017
regulation of immune system processGO:00026821230.017
positive regulation of immune responseGO:0050778420.017
positive regulation of cellular amine metabolic processGO:003324030.016
vesicle mediated transportGO:00161921810.016
cellular response to stressGO:00335542690.016
peptide hormone secretionGO:0030072840.016
endocytosisGO:0006897840.016
cellular response to oxygen containing compoundGO:19017013860.016
cellular nitrogen compound catabolic processGO:00442701630.016
unsaturated fatty acid metabolic processGO:0033559390.016
cognitionGO:0050890920.016
metal ion transportGO:00300012890.016
development of primary sexual characteristicsGO:00451371070.016
generation of precursor metabolites and energyGO:0006091620.016
regulation of lipid metabolic processGO:0019216680.016
long chain fatty acid metabolic processGO:0001676320.015
apoptotic signaling pathwayGO:0097190270.015
response to organophosphorusGO:00466831020.015
nucleoside bisphosphate metabolic processGO:003386510.015
reproductionGO:00000032450.015
regulation of ion transportGO:00432692450.015
proteolysisGO:00065081750.015
glycosyl compound metabolic processGO:19016571820.015
response to ketoneGO:19016541820.015
response to hypoxiaGO:00016662310.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
lipid localizationGO:0010876620.015
calcium ion transportGO:00068161310.015
regulation of peptide hormone secretionGO:0090276800.015
cellular calcium ion homeostasisGO:00068741600.015
peptide transportGO:0015833970.015
agingGO:00075682410.015
cellular amino acid metabolic processGO:00065201070.015
nucleic acid templated transcriptionGO:00976593790.015
monosaccharide metabolic processGO:0005996610.014
response to woundingGO:00096112540.014
cytokine biosynthetic processGO:004208930.014
positive regulation of hydrolase activityGO:0051345860.014
negative regulation of secretionGO:0051048820.014
purine ribonucleotide metabolic processGO:00091502270.014
regulation of dna metabolic processGO:0051052600.014
negative regulation of macromolecule metabolic processGO:00106052600.014
synaptic transmissionGO:00072682350.014
g protein coupled receptor signaling pathwayGO:00071862420.013
response to fatty acidGO:0070542650.013
regulation of peptide secretionGO:0002791820.013
cellular response to molecule of bacterial originGO:0071219560.013
positive regulation of signal transductionGO:00099671750.013
regulation of apoptotic processGO:00429813350.013
Rat
negative regulation of gene expressionGO:00106291990.013
positive regulation of phosphorylationGO:00423271770.013
small molecule catabolic processGO:0044282590.013
lymphocyte mediated immunityGO:0002449140.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
positive regulation of defense responseGO:0031349370.013
response to estradiolGO:00323551640.013
regulation of phosphorus metabolic processGO:00511743490.013
urogenital system developmentGO:0001655780.013
response to cytokineGO:00340972150.013
ossificationGO:0001503700.013
immune system processGO:00023762040.013
neurological system processGO:00508772190.013
ribonucleotide metabolic processGO:00092592310.013
lipid transportGO:0006869610.013
myeloid leukocyte activationGO:0002274360.012
small molecule biosynthetic processGO:00442831240.012
positive regulation of lipid metabolic processGO:0045834330.012
action potentialGO:0001508540.012
negative regulation of transportGO:00510511360.012
female pregnancyGO:00075651220.012
steroid metabolic processGO:0008202730.012
cellular response to lipopolysaccharideGO:0071222550.012
regulation of secretionGO:00510462240.012
response to campGO:0051591910.012
positive regulation of cellular component organizationGO:00511302000.012
cell type specific apoptotic processGO:00972851340.012
positive regulation of nervous system developmentGO:00519621780.012
protein complex subunit organizationGO:00718223020.012
negative regulation of cell deathGO:00605482290.012
immune response regulating signaling pathwayGO:0002764190.012
macromolecular complex assemblyGO:00650032730.012
protein processingGO:0016485680.012
icosanoid metabolic processGO:0006690380.012
negative regulation of programmed cell deathGO:00430691830.012
transmission of nerve impulseGO:0019226420.012
cation transportGO:00068123820.012
divalent inorganic cation transportGO:00725111340.012
positive regulation of catalytic activityGO:00430851840.012
fatty acid oxidationGO:0019395290.012
organ regenerationGO:00311001010.012
response to estrogenGO:00436272320.011
purine containing compound catabolic processGO:00725231380.011
regulation of phosphate metabolic processGO:00192203490.011
purine ribonucleoside metabolic processGO:00461281680.011
regulation of cellular protein metabolic processGO:00322682670.011
cellular modified amino acid metabolic processGO:0006575610.011
cellular ion homeostasisGO:00068731840.011
regulation of cellular amino acid metabolic processGO:000652120.011
cation homeostasisGO:00550801950.011
regulation of blood circulationGO:19035221100.011
reproductive structure developmentGO:00486081280.011
transcription from rna polymerase ii promoterGO:00063662520.011
acetate ester biosynthetic processGO:190062020.011
positive regulation of biosynthetic processGO:00098913190.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
divalent inorganic cation homeostasisGO:00725071650.011
response to reactive oxygen speciesGO:00003021200.010
positive regulation of jak stat cascadeGO:0046427190.010
innate immune response activating signal transductionGO:000275890.010
circulatory system processGO:00030131830.010
positive regulation of cellular protein metabolic processGO:00322701670.010
negative regulation of cellular metabolic processGO:00313242810.010
positive regulation of transportGO:00510502450.010
multicellular organism growthGO:003526410.010
nucleoside metabolic processGO:00091161790.010
ras protein signal transductionGO:0007265290.010
regulation of transcription from rna polymerase ii promoterGO:00063572340.010
sex differentiationGO:00075481130.010
regulation of protein phosphorylationGO:00019321830.010
regulation of ion homeostasisGO:2000021630.010

Smpdl3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.072
inherited metabolic disorderDOID:65500.066
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.047
lipid storage diseaseDOID:945500.020
lysosomal storage diseaseDOID:321100.020
sensory system diseaseDOID:005015500.020
central nervous system diseaseDOID:33100.012