Rattus norvegicus

57 known processes

Tdo2

tryptophan 2,3-dioxygenase

(Aliases: TO,Tdo)

Tdo2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.372
response to inorganic substanceGO:00100353770.350
aromatic amino acid family metabolic processGO:000907290.335
carboxylic acid biosynthetic processGO:0046394830.298
carboxylic acid metabolic processGO:00197522890.263
cellular amino acid metabolic processGO:00065201070.262
organic acid biosynthetic processGO:0016053830.257
cellular response to oxygen containing compoundGO:19017013860.247
cellular response to organonitrogen compoundGO:00714171970.240
response to nutrientGO:00075842480.235
response to corticosteroidGO:00319602350.218
response to extracellular stimulusGO:00099913800.214
organic substance catabolic processGO:19015753160.203
small molecule biosynthetic processGO:00442831240.197
response to metal ionGO:00100382530.178
response to bacteriumGO:00096172000.172
single organism biosynthetic processGO:00447113420.170
response to oxygen levelsGO:00704822650.170
cellular lipid metabolic processGO:00442552080.169
regulation of serine type peptidase activityGO:190257110.168
alpha amino acid metabolic processGO:1901605710.162
response to insulinGO:00328681330.162
aromatic amino acid family catabolic processGO:000907470.161
response to other organismGO:00517072200.160
cellular response to organic cyclic compoundGO:00714072020.153
response to peptide hormoneGO:00434342780.148
response to ketoneGO:19016541820.145
response to nutrient levelsGO:00316673700.145
catabolic processGO:00090563510.142
alkaloid metabolic processGO:000982030.142
response to decreased oxygen levelsGO:00362932370.133
response to molecule of bacterial originGO:00022371940.129
response to glucocorticoidGO:00513842230.128
cellular response to lipidGO:00713962010.128
response to lipopolysaccharideGO:00324961910.125
response to biotic stimulusGO:00096072260.123
homeostatic processGO:00425923310.122
urea metabolic processGO:001962750.121
cellular homeostasisGO:00197252520.119
anatomical structure morphogenesisGO:00096532980.118
negative regulation of protein metabolic processGO:00512481140.114
response to acid chemicalGO:00011012220.114
organonitrogen compound catabolic processGO:19015651790.111
exogenous drug catabolic processGO:004273810.110
response to external biotic stimulusGO:00432072210.107
chemical homeostasisGO:00488782920.106
inflammatory responseGO:00069541500.105
response to peptideGO:19016522920.102
cellular response to steroid hormone stimulusGO:0071383930.100
single organism catabolic processGO:00447122830.098
blood circulationGO:00080151830.098
organic acid metabolic processGO:00060822920.097
oxidation reduction processGO:00551143040.093
cellular response to hormone stimulusGO:00328702470.093
nitrogen cycle metabolic processGO:007194150.092
regulation of neurogenesisGO:00507672470.089
protein phosphorylationGO:00064683450.088
regulation of cell developmentGO:00602842630.087
positive regulation of neurogenesisGO:00507691650.079
cellular component biogenesisGO:00440853680.078
lipid metabolic processGO:00066292830.078
regulation of system processGO:00440572080.076
regulation of protein metabolic processGO:00512462890.075
alpha amino acid catabolic processGO:1901606200.074
response to starvationGO:0042594590.073
negative regulation of metabolic processGO:00098923310.071
isoprenoid metabolic processGO:0006720450.071
response to estrogenGO:00436272320.067
reproductive processGO:00224143720.067
intracellular signal transductionGO:00355563140.067
negative regulation of cellular protein metabolic processGO:00322691060.066
cellular chemical homeostasisGO:00550822470.066
regulation of nervous system developmentGO:00519602640.066
negative regulation of cellular metabolic processGO:00313242810.065
regulation of cellular ketone metabolic processGO:0010565270.065
regulation of protein phosphorylationGO:00019321830.064
halogenated hydrocarbon metabolic processGO:004219740.062
apoptotic processGO:00069153810.062
cellular response to alcoholGO:0097306870.062
ion homeostasisGO:00508012120.062
response to hypoxiaGO:00016662310.059
regulation of membrane potentialGO:00423911100.059
regulation of catalytic activityGO:00507903040.058
metal ion transportGO:00300012890.056
cellular amino acid biosynthetic processGO:0008652320.055
positive regulation of nervous system developmentGO:00519621780.055
negative regulation of molecular functionGO:00440921330.054
regulation of metal ion transportGO:00109591180.054
macromolecule localizationGO:00330362520.052
cellular response to endogenous stimulusGO:00714953770.050
response to glucoseGO:00097491360.050
multi organism reproductive processGO:00447032620.050
single organism behaviorGO:00447081300.049
cellular component assemblyGO:00226073600.048
cellular response to campGO:0071320260.048
response to chromateGO:004668730.047
response to carbohydrateGO:00097431830.047
cellular response to alkaloidGO:0071312250.047
aromatic compound catabolic processGO:00194391680.047
negative regulation of cell deathGO:00605482290.046
defense responseGO:00069521940.046
regulation of neurological system processGO:0031644430.046
reactive oxygen species metabolic processGO:0072593370.045
negative regulation of macromolecule metabolic processGO:00106052600.045
response to estradiolGO:00323551640.045
cellular response to nitrogen compoundGO:19016992100.045
acute inflammatory responseGO:0002526580.045
regulation of lipid metabolic processGO:0019216680.044
regulation of cellular localizationGO:00603412630.044
calcitriol biosynthetic process from calciolGO:003637820.044
monocarboxylic acid biosynthetic processGO:0072330480.043
multi multicellular organism processGO:00447061380.043
multicellular organismal signalingGO:0035637440.042
divalent metal ion transportGO:00708381320.042
glycosyl compound metabolic processGO:19016571820.042
monocarboxylic acid metabolic processGO:00327871520.042
cellular ion homeostasisGO:00068731840.041
response to vitamin b6GO:003451610.041
programmed cell deathGO:00125013920.041
urea cycleGO:000005050.041
cellular hormone metabolic processGO:0034754490.040
regulation of cell differentiationGO:00455953200.040
alpha amino acid biosynthetic processGO:1901607230.040
regulation of protein modification processGO:00313991940.039
response to vitaminGO:00332731310.039
regulation of molecular functionGO:00650093980.039
cellular ketone metabolic processGO:0042180510.039
regulation of hydrolase activityGO:00513361430.039
positive regulation of multicellular organismal processGO:00512403870.038
negative regulation of peptidase activityGO:0010466380.038
circulatory system processGO:00030131830.037
positive regulation of response to stimulusGO:00485842850.037
regulation of cellular protein metabolic processGO:00322682670.036
response to cytokineGO:00340972150.036
peptidyl amino acid modificationGO:00181931260.036
regulation of phosphorylationGO:00423252480.035
secretionGO:00469033070.035
cellular response to peptide hormone stimulusGO:00713751200.035
positive regulation of molecular functionGO:00440932300.035
lipid localizationGO:0010876620.035
cellular response to glucocorticoid stimulusGO:0071385680.035
cation homeostasisGO:00550801950.034
cellular modified amino acid metabolic processGO:0006575610.034
response to fatty acidGO:0070542650.034
response to alkaloidGO:00432791320.034
cellular response to insulin stimulusGO:0032869810.034
cellular cation homeostasisGO:00300031800.033
positive regulation of cell developmentGO:00107201760.033
regulation of programmed cell deathGO:00430673410.033
behaviorGO:00076102050.032
regulation of blood pressureGO:0008217830.032
regulation of apoptotic processGO:00429813350.032
renin angiotensin regulation of aldosterone productionGO:000201830.032
neurological system processGO:00508772190.032
positive regulation of neuron projection developmentGO:0010976990.032
response to transition metal nanoparticleGO:19902671220.031
single organism intracellular transportGO:19025821660.031
intracellular transportGO:00469071850.031
transmission of nerve impulseGO:0019226420.031
regulation of reactive oxygen species metabolic processGO:2000377260.030
anion transportGO:00068201780.030
positive regulation of cellular component organizationGO:00511302000.029
negative regulation of gene expressionGO:00106291990.029
response to ethanolGO:00454711620.029
tissue developmentGO:00098882520.029
positive regulation of phosphorylationGO:00423271770.029
cation transportGO:00068123820.028
carbohydrate derivative metabolic processGO:19011353460.028
amine metabolic processGO:0009308380.028
multicellular organism reproductionGO:00325042330.028
regulation of serine type endopeptidase activityGO:190000310.028
regulation of intracellular signal transductionGO:19025312180.028
regulation of cellular amino acid metabolic processGO:000652120.028
regulation of protein maturationGO:1903317500.028
response to organophosphorusGO:00466831020.028
positive regulation of intracellular signal transductionGO:19025331380.027
female pregnancyGO:00075651220.027
response to reactive oxygen speciesGO:00003021200.027
purine containing compound metabolic processGO:00725212530.027
cellular response to stressGO:00335542690.026
proteolysisGO:00065081750.026
negative regulation of programmed cell deathGO:00430691830.026
response to corticosteroneGO:0051412400.026
regulation of response to woundingGO:1903034690.026
fatty acid metabolic processGO:0006631990.026
reproductionGO:00000032450.026
organophosphate metabolic processGO:00196373700.026
organic hydroxy compound metabolic processGO:19016151150.025
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.025
positive regulation of neuron differentiationGO:00456661260.025
protein complex subunit organizationGO:00718223020.025
negative regulation of apoptotic processGO:00430661810.025
extracellular matrix constituent secretionGO:007027840.025
negative regulation of protein maturationGO:1903318470.025
regulation of inflammatory responseGO:0050727480.025
positive regulation of cell differentiationGO:00455972170.025
regulation of body fluid levelsGO:0050878900.025
response to xenobiotic stimulusGO:0009410230.025
cellular nitrogen compound catabolic processGO:00442701630.024
cellular catabolic processGO:00442482950.024
positive regulation of catalytic activityGO:00430851840.024
cellular response to corticosteroid stimulusGO:0071384690.024
gland developmentGO:00487321550.024
regulation of neuron projection developmentGO:00109751610.024
negative regulation of serine type peptidase activityGO:190257210.024
hepaticobiliary system developmentGO:0061008900.023
pteridine containing compound metabolic processGO:0042558140.023
cellular response to external stimulusGO:00714961180.023
regulation of cellular amine metabolic processGO:003323880.023
negative regulation of response to stimulusGO:00485851550.023
lipid transportGO:0006869610.023
cellular amine metabolic processGO:0044106380.023
cellular response to ketoneGO:1901655510.023
urogenital system developmentGO:0001655780.023
glucose homeostasisGO:0042593750.023
response to mineralocorticoidGO:0051385490.022
response to retinoic acidGO:0032526630.022
regulation of growthGO:00400081050.022
nitrogen compound transportGO:00717052290.022
neuronal action potentialGO:0019228350.021
negative regulation of nitrogen compound metabolic processGO:00511721610.021
organelle organizationGO:00069962660.021
regulation of multicellular organismal developmentGO:20000263760.021
peptidyl tyrosine phosphorylationGO:0018108720.021
heart contractionGO:0060047570.021
cytoplasmic transportGO:00164821150.021
circulatory system developmentGO:00723591340.021
cellular response to cytokine stimulusGO:00713451270.021
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.020
regulation of cellular catabolic processGO:00313291010.020
insecticide metabolic processGO:001714340.020
organophosphate catabolic processGO:00464341480.020
neuron deathGO:00709971270.020
nucleoside metabolic processGO:00091161790.020
tube developmentGO:0035295890.020
macromolecular complex subunit organizationGO:00439333390.020
negative regulation of catalytic activityGO:00430861030.020
positive regulation of cell deathGO:00109421840.020
single organism reproductive processGO:00447022970.020
regulation of cell proliferationGO:00421273590.020
negative regulation of proteolysisGO:0045861410.020
circadian rhythmGO:0007623880.020
regulation of phosphate metabolic processGO:00192203490.020
immune responseGO:00069551040.019
negative regulation of protein processingGO:0010955470.019
regulation of phosphorus metabolic processGO:00511743490.019
glycogen metabolic processGO:0005977230.019
agingGO:00075682410.019
response to monosaccharideGO:00342841590.019
peptide secretionGO:0002790860.019
positive regulation of signalingGO:00230562700.019
cellular response to oxygen levelsGO:0071453600.019
hormone metabolic processGO:0042445690.019
response to temperature stimulusGO:0009266940.018
activation of protein kinase activityGO:0032147470.018
4 nitrophenol metabolic processGO:001896010.018
protein complex biogenesisGO:00702712630.018
regulation of neuron deathGO:19012141150.018
response to purine containing compoundGO:00140741260.018
gamete generationGO:00072761240.018
regulation of lipid biosynthetic processGO:0046890380.018
regulation of catabolic processGO:00098941130.018
cellular response to acid chemicalGO:0071229750.018
cell type specific apoptotic processGO:00972851340.018
positive regulation of reactive oxygen species metabolic processGO:2000379160.018
positive regulation of cellular biosynthetic processGO:00313282950.018
negative regulation of neuron deathGO:1901215690.018
positive regulation of protein metabolic processGO:00512471780.018
vesicle mediated transportGO:00161921810.018
brain renin angiotensin systemGO:000203530.018
growthGO:00400071650.018
retinoid metabolic processGO:0001523240.018
terpenoid metabolic processGO:0006721370.018
positive regulation of biosynthetic processGO:00098913190.018
cellular amino acid catabolic processGO:0009063210.017
response to mechanical stimulusGO:00096121340.017
organ regenerationGO:00311001010.017
cellular response to growth factor stimulusGO:00713631620.017
steroid biosynthetic processGO:0006694480.017
response to oxidative stressGO:00069791860.017
response to hexoseGO:00097461440.017
positive regulation of protein modification processGO:00314011420.017
energy derivation by oxidation of organic compoundsGO:0015980460.017
angiotensin mediated drinking behaviorGO:000305120.017
response to interferon gammaGO:0034341200.017
synaptic vesicle amine transportGO:001584230.017
protein maturationGO:0051604680.017
multicellular organismal reproductive processGO:00486092330.017
regulation of cellular component organizationGO:00511283680.016
ribonucleoside metabolic processGO:00091191740.016
steroid metabolic processGO:0008202730.016
positive regulation of lipid biosynthetic processGO:0046889250.016
liver developmentGO:0001889900.016
catenin import into nucleusGO:003541110.016
positive regulation of developmental processGO:00510942830.016
single organism carbohydrate metabolic processGO:00447231180.016
regulation of rna biosynthetic processGO:20011413810.016
response to light stimulusGO:0009416520.016
heart processGO:0003015570.016
nucleocytoplasmic transportGO:0006913480.016
cell growthGO:00160491040.016
vascular process in circulatory systemGO:0003018960.016
nucleobase containing compound catabolic processGO:00346551520.016
male gamete generationGO:0048232990.016
positive regulation of cell projection organizationGO:00313461110.016
intracellular protein transportGO:0006886790.016
protein transportGO:00150311320.015
regenerationGO:00310991630.015
carbohydrate derivative catabolic processGO:19011361470.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
muscle system processGO:00030121150.015
reactive nitrogen species metabolic processGO:200105710.015
negative regulation of signal transductionGO:0009968830.015
fatty acid transportGO:0015908250.015
positive regulation of nucleobase containing compound metabolic processGO:00459353190.015
monovalent inorganic cation transportGO:00156721720.015
ion transmembrane transportGO:00342203650.015
spermatogenesisGO:0007283990.015
positive regulation of cellular amine metabolic processGO:003324030.015
small molecule catabolic processGO:0044282590.015
negative regulation of transcription regulatory region dna bindingGO:200067820.014
negative regulation of vasculature developmentGO:1901343110.014
protein oligomerizationGO:00512591910.014
positive regulation of hormone secretionGO:0046887650.014
response to radiationGO:00093141370.014
regulation of nucleic acid templated transcriptionGO:19035063800.014
macromolecular complex assemblyGO:00650032730.014
linoleic acid metabolic processGO:004365140.014
glucan metabolic processGO:0044042230.014
cellular metal ion homeostasisGO:00068751720.014
synaptic transmissionGO:00072682350.014
icosanoid metabolic processGO:0006690380.014
divalent inorganic cation transportGO:00725111340.014
kidney developmentGO:0001822670.014
cellular response to reactive oxygen speciesGO:0034614550.014
sensory perceptionGO:00076001010.014
response to growth factorGO:00708481890.014
regulation of muscle system processGO:0090257790.014
head developmentGO:00603222470.014
lipid biosynthetic processGO:00086101280.014
negative regulation of rna metabolic processGO:00512531230.014
cardiovascular system developmentGO:00723581340.014
signal transduction by phosphorylationGO:00230141440.014
carboxylic acid catabolic processGO:0046395490.014
purine nucleoside metabolic processGO:00422781690.013
regulation of cell migrationGO:00303341280.013
axis specificationGO:000979840.013
glial cell differentiationGO:0010001650.013
negative regulation of endopeptidase activityGO:0010951360.013
cell cell signalingGO:00072673350.013
negative regulation of phosphate metabolic processGO:0045936800.013
secretion by cellGO:00329402480.013
regulation of secretionGO:00510462240.013
action potentialGO:0001508540.013
response to muscle activity involved in regulation of muscle adaptationGO:001487320.013
regulation of tube sizeGO:0035150890.013
cellular response to glucose stimulusGO:0071333650.013
positive regulation of programmed cell deathGO:00430681570.013
cellular polysaccharide metabolic processGO:0044264230.013
organic cyclic compound catabolic processGO:19013611750.013
positive regulation of cellular protein metabolic processGO:00322701670.013
nucleobase containing small molecule metabolic processGO:00550863160.013
carbohydrate homeostasisGO:0033500750.013
feeding behaviorGO:0007631530.013
cellular sodium ion homeostasisGO:000688340.013
central nervous system developmentGO:00074173110.013
sulfur compound metabolic processGO:0006790700.013
negative regulation of phosphorylationGO:0042326570.013
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.013
regulation of peptidase activityGO:0052547550.013
cellular component movementGO:00069282480.013
positive regulation of phosphorus metabolic processGO:00105622620.013
response to toxic substanceGO:00096361330.013
response to amphetamineGO:0001975250.013
localization of cellGO:00516742020.012
negative regulation of hydrolase activityGO:0051346520.012
chemotaxisGO:0006935660.012
response to vitamin aGO:0033189360.012
carbohydrate metabolic processGO:00059751300.012
heart morphogenesisGO:000300730.012
g protein coupled receptor signaling pathwayGO:00071862420.012
positive regulation of extracellular matrix organizationGO:190305540.012
regulation of proteolysisGO:0030162660.012
regulation of anatomical structure sizeGO:00900661350.012
organic acid catabolic processGO:0016054490.012
regulation of transferase activityGO:00513381230.012
regulation of hormone levelsGO:00108171870.012
purine nucleotide metabolic processGO:00061632290.012
cellular response to peptideGO:19016531330.012
regulation of ion transportGO:00432692450.012
response to lead ionGO:0010288330.012
chlorinated hydrocarbon metabolic processGO:004219640.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
diterpenoid metabolic processGO:0016101330.012
nucleoside phosphate catabolic processGO:19012921400.012
regulation of calcium ion transportGO:0051924770.012
regulation of response to external stimulusGO:00321011060.012
protein tetramerizationGO:0051262380.012
monovalent inorganic cation homeostasisGO:0055067360.012
response to activityGO:0014823730.012
protein processingGO:0016485680.012
organonitrogen compound biosynthetic processGO:19015661670.012
positive regulation of behaviorGO:0048520380.012
cellular response to oxidative stressGO:0034599760.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
positive regulation of mapk cascadeGO:0043410920.012
ossificationGO:0001503700.012
positive regulation of immunoglobulin productionGO:000263940.011
response to campGO:0051591910.011
nucleotide metabolic processGO:00091172790.011
drug catabolic processGO:004273710.011
regulation of renal sodium excretionGO:0035813200.011
regulation of epithelial cell proliferationGO:0050678490.011
negative regulation of protein phosphorylationGO:0001933440.011
cellular glucan metabolic processGO:0006073230.011
cellular response to xenobiotic stimulusGO:0071466190.011
positive regulation of signal transductionGO:00099671750.011
glucose metabolic processGO:0006006520.011
negative regulation of phosphorus metabolic processGO:0010563800.011
single organism cellular localizationGO:19025801020.011
response to foodGO:0032094270.011
positive regulation of cellular catabolic processGO:0031331710.011
metal ion homeostasisGO:00550651860.011
regulation of signal transductionGO:00099663180.011
hexose metabolic processGO:0019318580.011
cofactor metabolic processGO:0051186950.011
cellular response to carbohydrate stimulusGO:0071322720.011
cytokine productionGO:0001816610.011
response to vitamin eGO:0033197240.011
telencephalon developmentGO:0021537620.011
calcium ion transportGO:00068161310.011
regulation of cell projection organizationGO:00313441750.011
regulation of defense responseGO:0031347680.011
regulation of blood circulationGO:19035221100.011
negative regulation of cellular amine metabolic processGO:003323930.011
negative regulation of cell communicationGO:00106481580.011
regulation of response to stressGO:00801341260.011
regulation of cell growthGO:0001558850.011
establishment of protein localizationGO:00451841410.011
negative regulation of multicellular organismal processGO:00512412030.011
brain developmentGO:00074202470.010
locomotionGO:00400112370.010
nuclear transportGO:0051169490.010
negative regulation of collagen biosynthetic processGO:003296640.010
estrogen metabolic processGO:0008210110.010
myelinationGO:0042552390.010
transmembrane transportGO:00550854120.010
positive regulation of nitrogen compound metabolic processGO:00511733340.010
regulation of protein processingGO:0070613500.010
coenzyme metabolic processGO:0006732860.010
positive regulation of lipid metabolic processGO:0045834330.010
lipid storageGO:001991510.010
fatty acid derivative metabolic processGO:1901568380.010
response to amineGO:0014075460.010

Tdo2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.025
inherited metabolic disorderDOID:65500.019
disease of anatomical entityDOID:700.018
cardiovascular system diseaseDOID:128700.018
vascular diseaseDOID:17800.014
hypertensionDOID:1076300.013
essential hypertensionDOID:1082500.013
artery diseaseDOID:005082800.013