IMP: Integrative Multi-species Prediction

Rattus norvegicus

38 known processes

Aqp7

aquaporin 7

Entrez: 29171
Ensembl: ENSRNOG00000009686
RGD: 2145
UniProtKB: P56403

Process Predictions
Disease Predictions

Aqp7 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular lipid metabolic process	GO:0044255	208	0.667
fatty acid metabolic process	GO:0006631	99	0.488
response to peptide	GO:1901652	292	0.463
anion transport	GO:0006820	178	0.450	Rat
lipid oxidation	GO:0034440	30	0.449
carboxylic acid metabolic process	GO:0019752	289	0.372
organic acid metabolic process	GO:0006082	292	0.364
fatty acid oxidation	GO:0019395	29	0.331
lipid metabolic process	GO:0006629	283	0.322
carboxylic acid transport	GO:0046942	115	0.316	Rat
response to corticosteroid	GO:0031960	235	0.273
carboxylic acid biosynthetic process	GO:0046394	83	0.251
response to fatty acid	GO:0070542	65	0.245
monocarboxylic acid metabolic process	GO:0032787	152	0.240
oxoacid metabolic process	GO:0043436	290	0.238
response to peptide hormone	GO:0043434	278	0.214
response to insulin	GO:0032868	133	0.202
organic anion transport	GO:0015711	132	0.184	Rat
lipid biosynthetic process	GO:0008610	128	0.172
response to glucocorticoid	GO:0051384	223	0.166
organic acid transport	GO:0015849	116	0.161	Rat
small molecule biosynthetic process	GO:0044283	124	0.157
response to acid chemical	GO:0001101	222	0.157
cellular response to peptide hormone stimulus	GO:0071375	120	0.152
monocarboxylic acid transport	GO:0015718	52	0.146	Rat
response to metal ion	GO:0010038	253	0.146
response to nutrient	GO:0007584	248	0.144
fatty acid catabolic process	GO:0009062	26	0.141
androgen biosynthetic process	GO:0006702	10	0.139
cellular response to organonitrogen compound	GO:0071417	197	0.139
response to inorganic substance	GO:0010035	377	0.134
nitrogen compound transport	GO:0071705	229	0.123
secretion	GO:0046903	307	0.121	Rat
lipid catabolic process	GO:0016042	46	0.115
organic acid catabolic process	GO:0016054	49	0.110
response to monosaccharide	GO:0034284	159	0.108
female pregnancy	GO:0007565	122	0.101
regulation of hormone levels	GO:0010817	187	0.098
lipid modification	GO:0030258	52	0.091
transmembrane transport	GO:0055085	412	0.088
response to bacterium	GO:0009617	200	0.086
intestinal absorption	GO:0050892	3	0.082
single organism biosynthetic process	GO:0044711	342	0.079
homeostatic process	GO:0042592	331	0.079	Mouse
regulation of phagocytosis engulfment	GO:0060099	4	0.078
cellular response to insulin stimulus	GO:0032869	81	0.078
long chain fatty acid transport	GO:0015909	14	0.076
cellular chemical homeostasis	GO:0055082	247	0.075
cellular ketone metabolic process	GO:0042180	51	0.074
ion transmembrane transport	GO:0034220	365	0.072
protein homooligomerization	GO:0051260	91	0.070
response to nutrient levels	GO:0031667	370	0.070
catabolic process	GO:0009056	351	0.069
protein complex subunit organization	GO:0071822	302	0.068
glutathione transport	GO:0034635	2	0.068
gland development	GO:0048732	155	0.066
organic substance catabolic process	GO:1901575	316	0.064
response to external biotic stimulus	GO:0043207	221	0.063
fatty acid transport	GO:0015908	25	0.062
central nervous system development	GO:0007417	311	0.062
cellular catabolic process	GO:0044248	295	0.062
cellular lipid catabolic process	GO:0044242	37	0.061
cellular component assembly	GO:0022607	360	0.060
response to mineralocorticoid	GO:0051385	49	0.060
response to extracellular stimulus	GO:0009991	380	0.060
regulation of multicellular organismal development	GO:2000026	376	0.059
positive regulation of lipid catabolic process	GO:0050996	4	0.058
response to carbohydrate	GO:0009743	183	0.058
multicellular organismal reproductive process	GO:0048609	233	0.055
response to transition metal nanoparticle	GO:1990267	122	0.055
cellular response to lipid	GO:0071396	201	0.054
regulation of fatty acid metabolic process	GO:0019217	18	0.054
fatty acid beta oxidation	GO:0006635	22	0.054
reproduction	GO:0000003	245	0.053
positive regulation of secretion	GO:0051047	140	0.051
small molecule catabolic process	GO:0044282	59	0.050
response to lipopolysaccharide	GO:0032496	191	0.050
response to estrogen	GO:0043627	232	0.049
regulation of secretion	GO:0051046	224	0.049
organic hydroxy compound metabolic process	GO:1901615	115	0.049
regulation of secretion by cell	GO:1903530	208	0.048
cellular component biogenesis	GO:0044085	368	0.048
single organism reproductive process	GO:0044702	297	0.048
apoptotic process	GO:0006915	381	0.048
protein complex assembly	GO:0006461	263	0.047
response to ketone	GO:1901654	182	0.046
macromolecule localization	GO:0033036	252	0.046	Rat
response to biotic stimulus	GO:0009607	226	0.046
response to zinc ion	GO:0010043	39	0.046
monocarboxylic acid catabolic process	GO:0072329	28	0.045
lipid localization	GO:0010876	62	0.044	Rat
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.044
response to ethanol	GO:0045471	162	0.042
amide transport	GO:0042886	105	0.042
programmed cell death	GO:0012501	392	0.042
cellular response to endogenous stimulus	GO:0071495	377	0.042
single organism catabolic process	GO:0044712	283	0.041
glycerolipid metabolic process	GO:0046486	67	0.041
cellular response to external stimulus	GO:0071496	118	0.041
response to other organism	GO:0051707	220	0.040
sulfur amino acid metabolic process	GO:0000096	9	0.040
regulation of cellular localization	GO:0060341	263	0.039
monosaccharide metabolic process	GO:0005996	61	0.038
cellular response to peptide	GO:1901653	133	0.038
negative regulation of cell death	GO:0060548	229	0.037
carboxylic acid catabolic process	GO:0046395	49	0.037
hormone metabolic process	GO:0042445	69	0.037
response to estradiol	GO:0032355	164	0.036
response to vitamin	GO:0033273	131	0.036
cation transport	GO:0006812	382	0.035
protein complex biogenesis	GO:0070271	263	0.035
digestive system process	GO:0022600	24	0.034
cellular hormone metabolic process	GO:0034754	49	0.034
organophosphate metabolic process	GO:0019637	370	0.034
brain development	GO:0007420	247	0.033
macromolecular complex assembly	GO:0065003	273	0.033
positive regulation of fatty acid oxidation	GO:0046321	6	0.032
long chain fatty acid metabolic process	GO:0001676	32	0.032
regulation of ion transport	GO:0043269	245	0.032
acetate ester biosynthetic process	GO:1900620	2	0.032
response to osmotic stress	GO:0006970	42	0.032
head development	GO:0060322	247	0.032
learning or memory	GO:0007611	90	0.031
regulation of synaptic transmission	GO:0050804	141	0.031
cellular response to stress	GO:0033554	269	0.031
regulation of peptide transport	GO:0090087	87	0.030
negative regulation of transport	GO:0051051	136	0.030
alcohol metabolic process	GO:0006066	77	0.030
phospholipid biosynthetic process	GO:0008654	29	0.029
cellular homeostasis	GO:0019725	252	0.029
response to nicotine	GO:0035094	51	0.029
aging	GO:0007568	241	0.028
terpenoid metabolic process	GO:0006721	37	0.028
reactive oxygen species metabolic process	GO:0072593	37	0.028
positive regulation of transport	GO:0051050	245	0.027
response to growth factor	GO:0070848	189	0.027
sexual reproduction	GO:0019953	148	0.027
organic acid biosynthetic process	GO:0016053	83	0.027
response to oxygen levels	GO:0070482	265	0.027
reproductive process	GO:0022414	372	0.027
signal transduction by phosphorylation	GO:0023014	144	0.026
protein localization	GO:0008104	191	0.026
response to purine containing compound	GO:0014074	126	0.026
multi organism reproductive process	GO:0044703	262	0.026
neutral lipid metabolic process	GO:0006638	21	0.026
response to calcium ion	GO:0051592	59	0.026
cell cell signaling	GO:0007267	335	0.026
developmental process involved in reproduction	GO:0003006	159	0.025
positive regulation of cell communication	GO:0010647	271	0.025
monocarboxylic acid biosynthetic process	GO:0072330	48	0.025
regulation of body fluid levels	GO:0050878	90	0.025	Mouse
response to hexose	GO:0009746	144	0.025
peptide transport	GO:0015833	97	0.025
cognition	GO:0050890	92	0.025
isoprenoid metabolic process	GO:0006720	45	0.025
regulation of lipid catabolic process	GO:0050994	12	0.025
cellular response to acid chemical	GO:0071229	75	0.024
single organism behavior	GO:0044708	130	0.024
fatty acid biosynthetic process	GO:0006633	33	0.024
regulation of cellular ketone metabolic process	GO:0010565	27	0.024
macromolecular complex subunit organization	GO:0043933	339	0.024
anatomical structure morphogenesis	GO:0009653	298	0.023
carbohydrate metabolic process	GO:0005975	130	0.023
cellular response to low density lipoprotein particle stimulus	GO:0071404	3	0.023
response to vitamin e	GO:0033197	24	0.023
acylglycerol metabolic process	GO:0006639	21	0.023
cellular response to nitrogen compound	GO:1901699	210	0.022
ion homeostasis	GO:0050801	212	0.022
positive regulation of signaling	GO:0023056	270	0.022
amino acid transport	GO:0006865	70	0.022
regulation of apoptotic process	GO:0042981	335	0.022
fatty acid transmembrane transport	GO:1902001	3	0.022
choline transport	GO:0015871	4	0.022
triglyceride metabolic process	GO:0006641	21	0.022
cellular amino acid metabolic process	GO:0006520	107	0.021
response to alkaloid	GO:0043279	132	0.021
regulation of programmed cell death	GO:0043067	341	0.021
positive regulation of phagocytosis engulfment	GO:0060100	4	0.021
regeneration	GO:0031099	163	0.021
blood circulation	GO:0008015	183	0.021
organic hydroxy compound transport	GO:0015850	77	0.021
positive regulation of cellular component organization	GO:0051130	200	0.021
negative regulation of apoptotic process	GO:0043066	181	0.020
lipid storage	GO:0019915	1	0.020
establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	1	0.020
defense response to gram positive bacterium	GO:0050830	2	0.020
amine metabolic process	GO:0009308	38	0.020
ras protein signal transduction	GO:0007265	29	0.020
regulation of anatomical structure morphogenesis	GO:0022603	141	0.020
cellular response to molecule of bacterial origin	GO:0071219	56	0.020
muscle contraction	GO:0006936	88	0.020
positive regulation of fatty acid metabolic process	GO:0045923	14	0.020
positive regulation of developmental process	GO:0051094	283	0.019
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.019
cellular modified amino acid metabolic process	GO:0006575	61	0.019
single organism carbohydrate metabolic process	GO:0044723	118	0.019
organ induction	GO:0001759	1	0.019
cellular amine metabolic process	GO:0044106	38	0.019
g protein coupled receptor signaling pathway	GO:0007186	242	0.019
cation transmembrane transport	GO:0098655	263	0.019
muscle structure development	GO:0061061	87	0.019
biological adhesion	GO:0022610	110	0.019
protein oligomerization	GO:0051259	191	0.018
cellular response to hormone stimulus	GO:0032870	247	0.018
retinoid metabolic process	GO:0001523	24	0.018
response to wounding	GO:0009611	254	0.018
response to glucose	GO:0009749	136	0.018
organophosphate biosynthetic process	GO:0090407	143	0.018
synaptic transmission	GO:0007268	235	0.018
negative regulation of innate immune response	GO:0045824	4	0.018
telencephalon development	GO:0021537	62	0.018
vitamin a metabolic process	GO:0006776	2	0.018
regulation of catalytic activity	GO:0050790	304	0.018
regulation of cell projection organization	GO:0031344	175	0.018
response to decreased oxygen levels	GO:0036293	237	0.018
developmental induction	GO:0031128	2	0.018
acyl coa metabolic process	GO:0006637	28	0.018
one carbon compound transport	GO:0019755	5	0.018
multicellular organism growth	GO:0035264	1	0.018
regulation of fatty acid oxidation	GO:0046320	10	0.017
negative regulation of secretion	GO:0051048	82	0.017
behavior	GO:0007610	205	0.017
cytosolic calcium ion homeostasis	GO:0051480	140	0.017
vitamin d receptor signaling pathway	GO:0070561	1	0.017
positive regulation of cell projection organization	GO:0031346	111	0.017
circulatory system process	GO:0003013	183	0.017
multi multicellular organism process	GO:0044706	138	0.017
regulation of blood pressure	GO:0008217	83	0.017
peptide hormone secretion	GO:0030072	84	0.017
antral ovarian follicle growth	GO:0001547	3	0.017
regulation of anion transport	GO:0044070	43	0.017
heterocycle catabolic process	GO:0046700	167	0.017
cellular response to fatty acid	GO:0071398	29	0.017
innate immune response	GO:0045087	35	0.017
cytoskeleton organization	GO:0007010	111	0.017
regulation of cation channel activity	GO:2001257	23	0.016
regulation of transmembrane transporter activity	GO:0022898	49	0.016
regulation of lipid metabolic process	GO:0019216	68	0.016
response to amino acid	GO:0043200	75	0.016
digestion	GO:0007586	26	0.016
positive regulation of ion transport	GO:0043270	94	0.016
regulation of catabolic process	GO:0009894	113	0.016
nucleobase containing small molecule metabolic process	GO:0055086	316	0.016
lipid transport	GO:0006869	61	0.016	Rat
negative regulation of programmed cell death	GO:0043069	183	0.016
response to mechanical stimulus	GO:0009612	134	0.016
neuron differentiation	GO:0030182	368	0.016
oxidation reduction process	GO:0055114	304	0.015
cellular metal ion homeostasis	GO:0006875	172	0.015
hormone transport	GO:0009914	121	0.015
tripeptide transport	GO:0042939	2	0.015
response to molecule of fungal origin	GO:0002238	3	0.015
insulin secretion	GO:0030073	69	0.015
monovalent inorganic cation transport	GO:0015672	172	0.015
sulfur compound metabolic process	GO:0006790	70	0.015
metal ion transport	GO:0030001	289	0.015
positive regulation of cell proliferation	GO:0008284	249	0.015
epithelium development	GO:0060429	96	0.015
chemical homeostasis	GO:0048878	292	0.015	Mouse
positive regulation of hormone secretion	GO:0046887	65	0.015
response to molecule of bacterial origin	GO:0002237	194	0.014
positive regulation of blood coagulation	GO:0030194	4	0.014
response to activity	GO:0014823	73	0.014
cellular response to nutrient levels	GO:0031669	60	0.014
innate immune response activating signal transduction	GO:0002758	9	0.014
neurological system process	GO:0050877	219	0.014
positive regulation of organic acid transport	GO:0032892	22	0.014
establishment of protein localization	GO:0045184	141	0.014
regulation of insulin secretion	GO:0050796	65	0.014
response to starvation	GO:0042594	59	0.014
hexose metabolic process	GO:0019318	58	0.014
specification of organ identity	GO:0010092	2	0.013
multicellular organism reproduction	GO:0032504	233	0.013
lateral ventricle development	GO:0021670	1	0.013
positive regulation of fatty acid beta oxidation	GO:0032000	4	0.013
regulation of necroptotic process	GO:0060544	2	0.013
cofactor metabolic process	GO:0051186	95	0.013
regulation of signal transduction	GO:0009966	318	0.013
cell projection organization	GO:0030030	302	0.013
regulation of fat cell proliferation	GO:0070344	1	0.013
regulation of blood circulation	GO:1903522	110	0.013
sodium ion transport	GO:0006814	82	0.013
leukocyte cell cell adhesion	GO:0007159	4	0.013
negative regulation of signaling	GO:0023057	157	0.013
regulation of ion homeostasis	GO:2000021	63	0.013
regulation of ion transmembrane transporter activity	GO:0032412	48	0.012
linoleic acid metabolic process	GO:0043651	4	0.012
cellular ion homeostasis	GO:0006873	184	0.012
regulation of phosphate metabolic process	GO:0019220	349	0.012
pyruvate metabolic process	GO:0006090	27	0.012
cellular response to organic cyclic compound	GO:0071407	202	0.012
cytokine secretion	GO:0050663	15	0.012
proteolysis	GO:0006508	175	0.012
positive regulation of multicellular organismal process	GO:0051240	387	0.012
memory	GO:0007613	54	0.012
response to corticosterone	GO:0051412	40	0.012
carnitine transport	GO:0015879	1	0.012
muscle system process	GO:0003012	115	0.012
alcohol biosynthetic process	GO:0046165	38	0.012
phosphatidylcholine biosynthetic process	GO:0006656	5	0.012
cellular response to lipopolysaccharide	GO:0071222	55	0.012
response to herbicide	GO:0009635	16	0.012
maintenance of location	GO:0051235	17	0.012
positive regulation of hemostasis	GO:1900048	4	0.012
neuron projection development	GO:0031175	273	0.012
acetyl coa metabolic process	GO:0006084	17	0.012
regulation of cellular amine metabolic process	GO:0033238	8	0.012
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.011
positive regulation of phosphorus metabolic process	GO:0010562	262	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
regulation of peptide hormone secretion	GO:0090276	80	0.011
anion transmembrane transport	GO:0098656	77	0.011
spermatogenesis	GO:0007283	99	0.011
inorganic ion transmembrane transport	GO:0098660	229	0.011
cation homeostasis	GO:0055080	195	0.011
cellular response to oxygen containing compound	GO:1901701	386	0.011
regulation of molecular function	GO:0065009	398	0.011
reactive oxygen species biosynthetic process	GO:1903409	8	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
cellular response to vitamin e	GO:0071306	3	0.011
carbohydrate phosphorylation	GO:0046835	16	0.011
regulation of response to stress	GO:0080134	126	0.011
positive regulation of cellular amine metabolic process	GO:0033240	3	0.011
peptide secretion	GO:0002790	86	0.011
intracellular signal transduction	GO:0035556	314	0.011
cellular cation homeostasis	GO:0030003	180	0.011
defense response to gram negative bacterium	GO:0050829	3	0.011
signal release	GO:0023061	145	0.011
organonitrogen compound biosynthetic process	GO:1901566	167	0.011
developmental growth	GO:0048589	100	0.011
cellular response to metal ion	GO:0071248	55	0.011
negative regulation of pancreatic stellate cell proliferation	GO:2000230	1	0.011
regulation of nervous system development	GO:0051960	264	0.010
cellular macromolecule localization	GO:0070727	122	0.010
reproductive structure development	GO:0048608	128	0.010
cytoplasmic transport	GO:0016482	115	0.010
calcium ion homeostasis	GO:0055074	162	0.010
secretion by cell	GO:0032940	248	0.010
locomotion	GO:0040011	237	0.010
mrna transcription	GO:0009299	2	0.010
regulation of transmembrane transport	GO:0034762	122	0.010
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.010

Aqp7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
overnutrition	DOID:654	0.257
acquired metabolic disease	DOID:0060158	0.257
nutrition disease	DOID:374	0.257
disease of metabolism	DOID:0014667	0.257
obesity	DOID:9970	0.086
muscle tissue disease	DOID:66	0.039
musculoskeletal system disease	DOID:17	0.039
disease of anatomical entity	DOID:7	0.039
muscular disease	DOID:0080000	0.039
myopathy	DOID:423	0.039
lipodystrophy	DOID:811	0.033
integumentary system disease	DOID:16	0.033
skin disease	DOID:37	0.033
muscular dystrophy	DOID:9884	0.025
nervous system disease	DOID:863	0.017
central nervous system disease	DOID:331	0.017

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