Rattus norvegicus

0 known processes

Adam3a

ADAM metallopeptidase domain 3A (cyritestin 1)

(Aliases: Adam3,tMDCI)

Adam3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of phosphorus metabolic processGO:00105622620.190
developmental growthGO:00485891000.184
regulation of cellular localizationGO:00603412630.182
reproductive processGO:00224143720.167
positive regulation of response to stimulusGO:00485842850.148
response to nutrient levelsGO:00316673700.141
urinary bladder smooth muscle contractionGO:001483240.128
regulation of molecular functionGO:00650093980.123
regulation of phosphorylationGO:00423252480.112
regulation of cell developmentGO:00602842630.108
regulation of secretionGO:00510462240.106
response to bacteriumGO:00096172000.103
regulation of hormone levelsGO:00108171870.097
regulation of protein metabolic processGO:00512462890.096
saliva secretionGO:004654130.094
regulation of epithelial cell proliferationGO:0050678490.090
response to radiationGO:00093141370.089
positive regulation of cell proliferationGO:00082842490.089
chemical homeostasisGO:00488782920.084
protein complex subunit organizationGO:00718223020.083
growthGO:00400071650.081
regulation of phosphate metabolic processGO:00192203490.079
macromolecule localizationGO:00330362520.079
g protein coupled receptor signaling pathwayGO:00071862420.078
secretion by cellGO:00329402480.078
regenerationGO:00310991630.074
sensory perceptionGO:00076001010.073
response to extracellular stimulusGO:00099913800.072
response to molecule of bacterial originGO:00022371940.070
regulation of phosphorus metabolic processGO:00511743490.070
regulation of multicellular organismal developmentGO:20000263760.069
regulation of cellular protein metabolic processGO:00322682670.066
reproductionGO:00000032450.065
multi organism reproductive processGO:00447032620.065
macromolecular complex subunit organizationGO:00439333390.064
urinary tract smooth muscle contractionGO:001484840.063
regulation of saliva secretionGO:004687730.063
somatostatin receptor signaling pathwayGO:003816940.060
ovulation cycleGO:0042698670.059
response to lipopolysaccharideGO:00324961910.057
negative regulation of cell deathGO:00605482290.056
positive regulation of cell communicationGO:00106472710.054
regulation of phosphatidylinositol dephosphorylationGO:006030410.054
regulation of response to external stimulusGO:00321011060.054
regulation of cell differentiationGO:00455953200.053
positive regulation of molecular functionGO:00440932300.052
intracellular signal transductionGO:00355563140.051
positive regulation of catalytic activityGO:00430851840.051
oxoacid metabolic processGO:00434362900.051
establishment of protein localizationGO:00451841410.050
response to hypoxiaGO:00016662310.050
cellular response to hormone stimulusGO:00328702470.050
regulation of secretion by cellGO:19035302080.049
response to glucocorticoidGO:00513842230.049
programmed cell deathGO:00125013920.048
positive regulation of protein metabolic processGO:00512471780.048
protein complex assemblyGO:00064612630.047
positive regulation of intracellular signal transductionGO:19025331380.047
positive regulation of epithelial cell proliferationGO:0050679320.047
protein phosphorylationGO:00064683450.046
cellular component assemblyGO:00226073600.046
response to estrogenGO:00436272320.045
response to biotic stimulusGO:00096072260.044
regulation of hormone secretionGO:00468831060.044
glycerolipid metabolic processGO:0046486670.043
regulation of signal transductionGO:00099663180.042
signal releaseGO:00230611450.040
protein complex biogenesisGO:00702712630.040
organelle organizationGO:00069962660.039
defecationGO:003042110.039
phasic smooth muscle contractionGO:001482130.039
positive regulation of transportGO:00510502450.038
regulation of nervous system developmentGO:00519602640.038
multicellular organism reproductionGO:00325042330.038
defense responseGO:00069521940.038
apoptotic processGO:00069153810.037
single organism reproductive processGO:00447022970.036
n methyl d aspartate receptor clusteringGO:009711420.036
positive regulation of cellular protein metabolic processGO:00322701670.036
cytoskeleton organizationGO:00070101110.036
regulation of protein phosphorylationGO:00019321830.035
response to alkaloidGO:00432791320.035
positive regulation of signal transductionGO:00099671750.035
metal ion homeostasisGO:00550651860.035
response to peptide hormoneGO:00434342780.034
response to ethanolGO:00454711620.034
cell activationGO:0001775970.034
organophosphate metabolic processGO:00196373700.034
organic acid metabolic processGO:00060822920.033
single organism organelle organizationGO:19025891800.033
actin filament based processGO:0030029860.032
amine metabolic processGO:0009308380.032
regulation of metal ion transportGO:00109591180.031
blood circulationGO:00080151830.031
cellular amine metabolic processGO:0044106380.031
regulation of ion transmembrane transportGO:00347651210.031
regulation of protein transportGO:0051223680.031
negative regulation of transportGO:00510511360.031
single organism biosynthetic processGO:00447113420.031
positive regulation of protein transportGO:0051222410.030
regulation of protein modification processGO:00313991940.030
multi multicellular organism processGO:00447061380.030
homeostatic processGO:00425923310.030
gland developmentGO:00487321550.030
response to external biotic stimulusGO:00432072210.030
negative regulation of luteinizing hormone secretionGO:003368540.029
response to oxygen levelsGO:00704822650.029
regulation of protein localizationGO:0032880810.028
epithelial cell proliferationGO:0050673540.028
peristalsisGO:003043220.028
negative regulation of uterine smooth muscle contractionGO:007047320.027
regulation of ion transmembrane transporter activityGO:0032412480.027
organic hydroxy compound metabolic processGO:19016151150.027
phosphatidylinositol dephosphorylationGO:004685640.027
response to ketoneGO:19016541820.027
regulation of exocytosisGO:0017157370.027
neuron differentiationGO:00301823680.027
regulation of apoptotic processGO:00429813350.027
response to antibioticGO:0046677390.027
cellular component biogenesisGO:00440853680.027
regulation of growthGO:00400081050.027
positive regulation of long term synaptic potentiationGO:190027340.027
multicellular organismal reproductive processGO:00486092330.027
cellular response to endogenous stimulusGO:00714953770.026
macromolecular complex assemblyGO:00650032730.026
ion transmembrane transportGO:00342203650.026
protein oligomerizationGO:00512591910.026
protein heterooligomerizationGO:0051291890.026
cation homeostasisGO:00550801950.026
response to other organismGO:00517072200.026
cellular response to cytokine stimulusGO:00713451270.026
purine containing compound metabolic processGO:00725212530.025
response to light stimulusGO:0009416520.025
synaptic transmissionGO:00072682350.025
positive regulation of programmed cell deathGO:00430681570.025
protein localizationGO:00081041910.025
response to woundingGO:00096112540.025
negative regulation of response to stimulusGO:00485851550.025
ras protein signal transductionGO:0007265290.025
regulation of membrane potentialGO:00423911100.025
protein transportGO:00150311320.024
cellular response to nitrogen compoundGO:19016992100.024
lipid metabolic processGO:00066292830.024
regulation of hydrolase activityGO:00513361430.024
cell cell signalingGO:00072673350.024
nucleotide metabolic processGO:00091172790.024
nucleotide catabolic processGO:00091661390.024
cellular lipid metabolic processGO:00442552080.024
nitrogen compound transportGO:00717052290.024
positive regulation of saliva secretionGO:004687830.024
development of primary sexual characteristicsGO:00451371070.024
immune responseGO:00069551040.024
carbohydrate homeostasisGO:0033500750.023
cellular protein localizationGO:00346131220.023
somatostatin signaling pathwayGO:003817040.023
behavioral response to cocaineGO:004814860.023
peptidyl amino acid modificationGO:00181931260.023
secretionGO:00469033070.023
positive regulation of cellular component organizationGO:00511302000.023
positive regulation of serotonin secretionGO:001406410.023
immune system processGO:00023762040.023
forebrain developmentGO:0030900980.023
carboxylic acid metabolic processGO:00197522890.023
positive regulation of growthGO:0045927550.023
regulation of establishment of protein localizationGO:0070201690.022
inorganic ion transmembrane transportGO:00986602290.022
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.022
intracellular transportGO:00469071850.022
positive regulation of signalingGO:00230562700.022
hormone secretionGO:00468791150.022
ovulation cycle processGO:0022602500.022
cellular macromolecule localizationGO:00707271220.022
regulation of immune system processGO:00026821230.022
protein homooligomerizationGO:0051260910.021
anatomical structure morphogenesisGO:00096532980.021
regulation of cellular component organizationGO:00511283680.021
organonitrogen compound biosynthetic processGO:19015661670.021
regulation of developmental growthGO:0048638450.021
cellular response to steroid hormone stimulusGO:0071383930.021
developmental process involved in reproductionGO:00030061590.021
ion homeostasisGO:00508012120.021
positive regulation of phosphorylationGO:00423271770.021
positive regulation of adenylate cyclase activityGO:0045762120.021
response to estradiolGO:00323551640.021
regulation of response to stressGO:00801341260.021
development of primary female sexual characteristicsGO:0046545560.021
regulation of transporter activityGO:0032409500.021
carbohydrate derivative biosynthetic processGO:19011371240.021
wound healingGO:00420601220.021
negative regulation of multicellular organismal processGO:00512412030.021
regulation of cell proliferationGO:00421273590.021
organonitrogen compound catabolic processGO:19015651790.020
response to reactive oxygen speciesGO:00003021200.020
hormone transportGO:00099141210.020
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.020
cellular component movementGO:00069282480.020
positive regulation of multicellular organismal processGO:00512403870.020
positive regulation of cyclase activityGO:0031281150.020
transmembrane transportGO:00550854120.020
ribonucleotide biosynthetic processGO:0009260850.020
response to metal ionGO:00100382530.020
positive regulation of protein kinase activityGO:0045860730.020
cellular response to oxygen containing compoundGO:19017013860.020
organ regenerationGO:00311001010.020
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.020
multicellular organism growthGO:003526410.020
cellular chemical homeostasisGO:00550822470.020
regulation of kinase activityGO:00435491170.020
insulin secretionGO:0030073690.020
response to decreased oxygen levelsGO:00362932370.019
regulation of feeding behaviorGO:0060259140.019
regulation of catalytic activityGO:00507903040.019
regulation of purine nucleotide biosynthetic processGO:1900371460.019
calcium ion homeostasisGO:00550741620.019
organic substance catabolic processGO:19015753160.019
lipid localizationGO:0010876620.019
diaphragm contractionGO:000208620.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
sex differentiationGO:00075481130.019
cellular amino acid metabolic processGO:00065201070.019
neurological system processGO:00508772190.019
glycerophospholipid metabolic processGO:0006650470.018
negative regulation of follicle stimulating hormone secretionGO:004688230.018
response to inorganic substanceGO:00100353770.018
adult locomotory behaviorGO:000834440.018
regulation of cellular amine metabolic processGO:003323880.018
gamete generationGO:00072761240.018
negative regulation of response to external stimulusGO:0032102370.018
regulation of purine nucleotide metabolic processGO:19005421150.018
locomotory exploration behaviorGO:003564110.018
regulation of intracellular signal transductionGO:19025312180.018
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.018
response to glucoseGO:00097491360.018
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189240.018
response to purine containing compoundGO:00140741260.017
positive regulation of secretion by cellGO:19035321280.017
intracellular protein transportGO:0006886790.017
regulation of peptide hormone secretionGO:0090276800.017
positive regulation of transferase activityGO:0051347810.017
cellular response to organonitrogen compoundGO:00714171970.017
gastric motilityGO:003548230.017
negative regulation of hormone secretionGO:0046888460.017
agingGO:00075682410.017
neuron deathGO:00709971270.017
glucose homeostasisGO:0042593750.017
catabolic processGO:00090563510.017
regulation of lyase activityGO:0051339220.017
heart morphogenesisGO:000300730.017
positive regulation of hormone secretionGO:0046887650.017
acute inflammatory responseGO:0002526580.017
positive regulation of the force of heart contraction by epinephrineGO:000305910.017
cytoplasmic transportGO:00164821150.017
nucleoside metabolic processGO:00091161790.016
response to peptideGO:19016522920.016
rho protein signal transductionGO:0007266110.016
positive regulation of developmental processGO:00510942830.016
small gtpase mediated signal transductionGO:0007264360.016
regulation of the force of heart contraction by chemical signalGO:000305720.016
neuropeptide signaling pathwayGO:0007218290.016
positive regulation of jak stat cascadeGO:0046427190.016
cellular response to stressGO:00335542690.016
glycosyl compound metabolic processGO:19016571820.016
neurotransmitter gated ion channel clusteringGO:007257830.016
negative regulation of programmed cell deathGO:00430691830.016
single organism cellular localizationGO:19025801020.016
monocarboxylic acid transportGO:0015718520.016
cardiac muscle cell contractionGO:0086003100.016
multicellular organismal response to stressGO:0033555250.016
response to corticosteroidGO:00319602350.016
negative regulation of defecationGO:200029310.016
positive regulation of protein modification processGO:00314011420.016
alcohol metabolic processGO:0006066770.016
negative regulation of calcium ion importGO:009028120.016
regulation of cell activationGO:0050865500.016
organelle localizationGO:0051640550.015
positive regulation of organelle organizationGO:0010638480.015
cellular metal ion homeostasisGO:00068751720.015
positive regulation of the force of heart contraction by norepinephrineGO:000306110.015
tumor necrosis factor biosynthetic processGO:004253310.015
regulation of organelle organizationGO:0033043800.015
response to hexoseGO:00097461440.015
regulation of transmembrane transportGO:00347621220.015
peptide transportGO:0015833970.015
negative regulation of secretion by cellGO:1903531720.015
neuromuscular synaptic transmissionGO:000727420.015
regulation of neurogenesisGO:00507672470.015
positive regulation of leukocyte degranulationGO:004330240.015
cell morphogenesisGO:00009021420.014
cellular response to peptide hormone stimulusGO:00713751200.014
positive regulation of secretionGO:00510471400.014
ribonucleoside metabolic processGO:00091191740.014
central nervous system developmentGO:00074173110.014
phospholipase c activating serotonin receptor signaling pathwayGO:000720820.014
regulation of transmembrane transporter activityGO:0022898490.014
regulation of neuron apoptotic processGO:0043523830.014
regulation of neurological system processGO:0031644430.014
serotonin receptor signaling pathwayGO:0007210100.014
regulation of cellular amino acid metabolic processGO:000652120.014
response to increased oxygen levelsGO:0036296450.014
lipid transportGO:0006869610.014
neuron projection developmentGO:00311752730.014
regulation of defecationGO:200029210.014
coenzyme metabolic processGO:0006732860.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressureGO:000202510.014
positive regulation of apoptotic processGO:00430651540.014
single organism catabolic processGO:00447122830.014
positive regulation of protein phosphorylationGO:00019341350.014
nucleoside phosphate metabolic processGO:00067532830.014
negative regulation of developmental processGO:00510931250.014
purine ribonucleotide metabolic processGO:00091502270.014
response to axon injuryGO:0048678590.014
exocytosisGO:0006887600.014
single organism behaviorGO:00447081300.014
peptidyl tyrosine phosphorylationGO:0018108720.014
negative regulation of smooth muscle contractionGO:004598670.014
positive regulation of cell deathGO:00109421840.014
peptide secretionGO:0002790860.014
regulation of synaptic plasticityGO:0048167700.014
ribonucleotide catabolic processGO:00092611360.014
neuromuscular processGO:005090520.014
cellular response to alkaloidGO:0071312250.013
positive regulation of purine nucleotide biosynthetic processGO:1900373360.013
response to fatty acidGO:0070542650.013
cellular response to drugGO:0035690300.013
amide transportGO:00428861050.013
positive regulation of gene expressionGO:00106282440.013
response to electrical stimulusGO:0051602560.013
positive regulation of the force of heart contraction by chemical signalGO:000309920.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
regulation of glutamate receptor signaling pathwayGO:1900449170.013
positive regulation of renin secretion into blood streamGO:190013510.013
regulation of sensory perception of painGO:0051930290.013
single organism membrane organizationGO:0044802740.013
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.013
regulation of nucleotide metabolic processGO:00061401170.013
vasoconstrictionGO:0042310540.013
nuclear transportGO:0051169490.013
positive regulation of cellular biosynthetic processGO:00313282950.013
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
rhythmic processGO:00485111560.013
response to painGO:0048265110.013
cellular response to hexose stimulusGO:0071331650.013
regulation of cyclase activityGO:0031279210.013
ribose phosphate metabolic processGO:00196932350.013
activation of protein kinase activityGO:0032147470.012
fertilizationGO:000956630.012
regulation of adenylate cyclase activityGO:0045761180.012
female pregnancyGO:00075651220.012
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.012
regulation of response to woundingGO:1903034690.012
response to testosteroneGO:0033574550.012
spermatogenesisGO:0007283990.012
negative adaptation of signaling pathwayGO:0022401100.012
kidney developmentGO:0001822670.012
protein processingGO:0016485680.012
male gamete generationGO:0048232990.012
epithelium developmentGO:0060429960.012
regulation of regulated secretory pathwayGO:190330570.012
exploration behaviorGO:003564010.012
cellular calcium ion homeostasisGO:00068741600.012
metal ion transportGO:00300012890.012
regulation of insulin secretionGO:0050796650.012
regulation of neuron deathGO:19012141150.012
cytokine mediated signaling pathwayGO:0019221430.012
response to tumor necrosis factorGO:0034612560.012
positive regulation of cell motilityGO:2000147970.012
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.012
cellular component morphogenesisGO:00329891550.012
cyclic purine nucleotide metabolic processGO:0052652620.012
neurotransmitter transportGO:0006836420.012
positive regulation of response to foodGO:003209730.012
negative regulation of response to woundingGO:1903035230.012
proteolysisGO:00065081750.012
cellular response to growth factor stimulusGO:00713631620.011
purine nucleoside metabolic processGO:00422781690.011
carbohydrate derivative catabolic processGO:19011361470.011
positive regulation of cell differentiationGO:00455972170.011
vesicle mediated transportGO:00161921810.011
ossificationGO:0001503700.011
negative regulation of blood vessel morphogenesisGO:2000181100.011
negative regulation of camp metabolic processGO:0030815140.011
defense response to gram negative bacteriumGO:005082930.011
regulation of defense responseGO:0031347680.011
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.011
female gonad developmentGO:0008585530.011
regulation of vasoconstrictionGO:0019229440.011
sequestering of metal ionGO:005123890.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
cellular response to glucocorticoid stimulusGO:0071385680.011
negative regulation of natural killer cell mediated immunityGO:000271640.011
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.011
regulation of synaptic vesicle exocytosisGO:200030060.011
positive regulation of protein secretionGO:0050714190.011
positive regulation of hydrolase activityGO:0051345860.011
micturitionGO:006007340.011
cell projection organizationGO:00300303020.011
response to indole 3 methanolGO:007168020.011
negative regulation of cyclic nucleotide metabolic processGO:0030800150.011
negative regulation of cellular protein metabolic processGO:00322691060.011
regulation of renin secretion into blood streamGO:190013310.011
response to morphineGO:0043278270.011
cation transportGO:00068123820.011
purine ribonucleoside metabolic processGO:00461281680.011
regulation of ossificationGO:0030278320.011
response to nutrientGO:00075842480.010
cellular catabolic processGO:00442482950.010
gonad developmentGO:00084061040.010
jak stat cascadeGO:0007259260.010
nucleobase containing compound catabolic processGO:00346551520.010
carboxylic acid transportGO:00469421150.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
brain renin angiotensin systemGO:000203530.010
positive regulation of nervous system developmentGO:00519621780.010
cellular response to carbohydrate stimulusGO:0071322720.010
triglyceride homeostasisGO:007032820.010
regulation of camp metabolic processGO:0030814430.010
sleepGO:0030431300.010
neuron developmentGO:00486662860.010
regulation of sensory perceptionGO:0051931290.010
leukocyte activationGO:0045321760.010
gtp metabolic processGO:0046039720.010
organophosphate catabolic processGO:00464341480.010
positive regulation of cellular amine metabolic processGO:003324030.010
ribonucleoside catabolic processGO:00424541260.010

Adam3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.019
disease of anatomical entityDOID:700.019
sensory system diseaseDOID:005015500.015
eye and adnexa diseaseDOID:149200.015
nervous system diseaseDOID:86300.015
eye diseaseDOID:561400.015
retinal degenerationDOID:846600.015
retinal diseaseDOID:567900.015
connective tissue diseaseDOID:6500.012