Rattus norvegicus

43 known processes

Cdkn2a

cyclin-dependent kinase inhibitor 2A

(Aliases: Arf,MTS1,p16,INK4A,p19ARF,p16Cdkn2a)

Cdkn2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna biosynthetic processGO:20011413810.089
response to toxic substanceGO:00096361330.078
cation transmembrane transportGO:00986552630.077
regulation of nucleic acid templated transcriptionGO:19035063800.076
cellular response to endogenous stimulusGO:00714953770.076
single organism reproductive processGO:00447022970.069
response to growth factorGO:00708481890.068
transmembrane transportGO:00550854120.066
regulation of programmed cell deathGO:00430673410.065
programmed cell deathGO:00125013920.064
circulatory system processGO:00030131830.063
ion transmembrane transportGO:00342203650.062
cellular response to stressGO:00335542690.058
response to decreased oxygen levelsGO:00362932370.055
organophosphate metabolic processGO:00196373700.055
regulation of apoptotic processGO:00429813350.054
ribonucleotide metabolic processGO:00092592310.054
reproductive processGO:00224143720.052
developmental process involved in reproductionGO:00030061590.051
immune system processGO:00023762040.049
calcium ion homeostasisGO:00550741620.048
positive regulation of nucleobase containing compound metabolic processGO:00459353190.045
nucleotide metabolic processGO:00091172790.043
cellular component assemblyGO:00226073600.043
regulation of cell proliferationGO:00421273590.043
positive regulation of response to stimulusGO:00485842850.043
cardiovascular system developmentGO:00723581340.043
regulation of cellular component organizationGO:00511283680.042
positive regulation of macromolecule biosynthetic processGO:00105572470.042
response to oxygen levelsGO:00704822650.042
oxoacid metabolic processGO:00434362900.041
positive regulation of transportGO:00510502450.039
response to nutrient levelsGO:00316673700.039
g protein coupled receptor signaling pathwayGO:00071862420.039
positive regulation of cell deathGO:00109421840.039
cellular homeostasisGO:00197252520.039
negative regulation of macromolecule biosynthetic processGO:00105581480.039
axis specificationGO:000979840.038
nucleoside metabolic processGO:00091161790.037
positive regulation of nitrogen compound metabolic processGO:00511733340.036
response to corticosteroidGO:00319602350.036
intracellular signal transductionGO:00355563140.035
cation transportGO:00068123820.035
cell projection organizationGO:00300303020.035
anterior posterior pattern specificationGO:000995210.035
response to estrogenGO:00436272320.035
positive regulation of biosynthetic processGO:00098913190.034
multicellular organism reproductionGO:00325042330.034
response to nutrientGO:00075842480.033
carbohydrate derivative metabolic processGO:19011353460.033
protein localizationGO:00081041910.033
regulation of neurogenesisGO:00507672470.033
reproductionGO:00000032450.033
macromolecular complex subunit organizationGO:00439333390.033
secretionGO:00469033070.033
single organism biosynthetic processGO:00447113420.032
apoptotic processGO:00069153810.032
nucleobase containing small molecule metabolic processGO:00550863160.032
regulation of secretionGO:00510462240.032
homeostatic processGO:00425923310.032
reproductive structure developmentGO:00486081280.032
response to other organismGO:00517072200.032
nitrogen compound transportGO:00717052290.032
embryonic pattern specificationGO:000988010.031
cellular response to lipidGO:00713962010.031
localization of cellGO:00516742020.031
macromolecule localizationGO:00330362520.030
response to hypoxiaGO:00016662310.030
ribonucleotide biosynthetic processGO:0009260850.030
regulation of system processGO:00440572080.030
secretion by cellGO:00329402480.030
response to molecule of bacterial originGO:00022371940.029
vascular process in circulatory systemGO:0003018960.029
regulation of molecular functionGO:00650093980.029
response to glucocorticoidGO:00513842230.029
cellular component biogenesisGO:00440853680.029
synaptic transmissionGO:00072682350.028
nucleic acid templated transcriptionGO:00976593790.028
monovalent inorganic cation transportGO:00156721720.028
positive regulation of secretionGO:00510471400.028
cellular response to growth factor stimulusGO:00713631620.028
rna biosynthetic processGO:00327743800.027
cell cell signalingGO:00072673350.027
ras protein signal transductionGO:0007265290.027
chemical homeostasisGO:00488782920.027
response to biotic stimulusGO:00096072260.027
single organism organelle organizationGO:19025891800.027
purine containing compound metabolic processGO:00725212530.027
single organism carbohydrate metabolic processGO:00447231180.027
cellular cation homeostasisGO:00300031800.027
regulation of phosphate metabolic processGO:00192203490.026
regulation of cellular catabolic processGO:00313291010.026
regulation of rna metabolic processGO:00512523910.026
positive regulation of cellular component organizationGO:00511302000.026
blood vessel developmentGO:0001568690.026
positive regulation of phosphorus metabolic processGO:00105622620.026
immune responseGO:00069551040.025
response to radiationGO:00093141370.025
central nervous system developmentGO:00074173110.025
anatomical structure morphogenesisGO:00096532980.025
catabolic processGO:00090563510.025
organophosphate biosynthetic processGO:00904071430.025
response to external biotic stimulusGO:00432072210.025
cellular macromolecule localizationGO:00707271220.025
regulation of transcription dna templatedGO:00063553740.025
cellular chemical homeostasisGO:00550822470.025
regulation of neuron differentiationGO:00456642080.025
negative regulation of metabolic processGO:00098923310.025
sex differentiationGO:00075481130.025
positive regulation of cell motilityGO:2000147970.024
response to ketoneGO:19016541820.024
cellular response to nitrogen compoundGO:19016992100.024
mapk cascadeGO:00001651400.024
neuron differentiationGO:00301823680.024
regulation of cell developmentGO:00602842630.024
positive regulation of cytosolic calcium ion concentrationGO:00072041220.024
cellular carbohydrate metabolic processGO:0044262720.024
cellular catabolic processGO:00442482950.024
defense responseGO:00069521940.024
cellular response to oxygen containing compoundGO:19017013860.024
positive regulation of ion transportGO:0043270940.024
motor neuron axon guidanceGO:000804510.023
organic acid metabolic processGO:00060822920.023
response to lipopolysaccharideGO:00324961910.023
neuron developmentGO:00486662860.023
regulation of protein localizationGO:0032880810.023
positive regulation of signalingGO:00230562700.023
embryonic axis specificationGO:000057810.023
nucleoside phosphate biosynthetic processGO:19012931020.023
blood circulationGO:00080151830.023
positive regulation of cell migrationGO:0030335960.023
positive regulation of cell communicationGO:00106472710.023
regulation of phosphorus metabolic processGO:00511743490.023
urogenital system developmentGO:0001655780.023
single organism behaviorGO:00447081300.022
negative regulation of multicellular organismal processGO:00512412030.022
positive regulation of purine nucleotide metabolic processGO:1900544910.022
regulation of cellular ketone metabolic processGO:0010565270.022
ribonucleoside triphosphate metabolic processGO:00091991410.022
regulation of blood circulationGO:19035221100.022
neuron projection developmentGO:00311752730.022
organic substance catabolic processGO:19015753160.022
cellular amine metabolic processGO:0044106380.022
regulation of cellular amino acid metabolic processGO:000652120.021
positive regulation of developmental processGO:00510942830.021
amine metabolic processGO:0009308380.021
positive regulation of cellular biosynthetic processGO:00313282950.021
response to bacteriumGO:00096172000.021
ribose phosphate metabolic processGO:00196932350.021
vasculature developmentGO:0001944700.021
organonitrogen compound biosynthetic processGO:19015661670.021
intracellular transportGO:00469071850.021
positive regulation of programmed cell deathGO:00430681570.021
behaviorGO:00076102050.021
forebrain developmentGO:0030900980.021
negative regulation of macromolecule metabolic processGO:00106052600.021
positive regulation of cell proliferationGO:00082842490.020
nucleoside phosphate metabolic processGO:00067532830.020
response to carbohydrateGO:00097431830.020
ribose phosphate biosynthetic processGO:0046390870.020
response to estradiolGO:00323551640.020
single organism catabolic processGO:00447122830.020
regulation of blood vessel sizeGO:0050880890.020
protein complex biogenesisGO:00702712630.020
regulation of cell migrationGO:00303341280.020
small gtpase mediated signal transductionGO:0007264360.020
regulation of protein transportGO:0051223680.020
bmp signaling pathwayGO:003050940.019
regulation of cellular component movementGO:00512701500.019
transmission of nerve impulseGO:0019226420.019
regulation of synaptic transmissionGO:00508041410.019
lipid metabolic processGO:00066292830.019
response to vitaminGO:00332731310.019
establishment of protein localizationGO:00451841410.019
positive regulation of transcription dna templatedGO:00458931970.019
negative regulation of cellular metabolic processGO:00313242810.019
regulation of cell differentiationGO:00455953200.019
response to cytokineGO:00340972150.019
positive regulation of rna metabolic processGO:00512542030.019
locomotionGO:00400112370.019
purine nucleoside triphosphate catabolic processGO:00091461220.018
regulation of secretion by cellGO:19035302080.018
cellular ketone metabolic processGO:0042180510.018
organelle organizationGO:00069962660.018
organophosphate catabolic processGO:00464341480.018
circulatory system developmentGO:00723591340.018
response to metal ionGO:00100382530.018
embryonic skeletal system morphogenesisGO:004870430.018
cellular macromolecular complex assemblyGO:0034622580.018
positive regulation of erk1 and erk2 cascadeGO:0070374290.018
single organism cellular localizationGO:19025801020.018
hepaticobiliary system developmentGO:0061008900.018
regulation of catalytic activityGO:00507903040.018
regulation of multicellular organismal developmentGO:20000263760.018
rna metabolic processGO:00160704060.018
sexual reproductionGO:00199531480.017
ossificationGO:0001503700.017
cellular component movementGO:00069282480.017
positive regulation of gene expressionGO:00106282440.017
regulation of neuron projection developmentGO:00109751610.017
muscle tissue developmentGO:0060537580.017
multi organism reproductive processGO:00447032620.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
positive regulation of signal transductionGO:00099671750.017
regulation of immune responseGO:0050776550.017
cell migrationGO:00164771970.017
enzyme linked receptor protein signaling pathwayGO:00071671160.017
purine ribonucleotide metabolic processGO:00091502270.017
negative regulation of gene expressionGO:00106291990.017
positive regulation of cell differentiationGO:00455972170.017
positive regulation of molecular functionGO:00440932300.017
renal system processGO:0003014400.017
regulation of cyclic nucleotide biosynthetic processGO:0030802450.017
purine nucleoside metabolic processGO:00422781690.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
transcription from rna polymerase ii promoterGO:00063662520.017
dendrite morphogenesisGO:0048813430.017
negative regulation of cell differentiationGO:0045596990.017
positive regulation of multicellular organismal processGO:00512403870.017
protein complex assemblyGO:00064612630.016
multicellular organismal reproductive processGO:00486092330.016
purine ribonucleoside metabolic processGO:00461281680.016
dendrite developmentGO:0016358720.016
protein complex subunit organizationGO:00718223020.016
organ regenerationGO:00311001010.016
rhythmic processGO:00485111560.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
cellular protein localizationGO:00346131220.016
organic acid transportGO:00158491160.016
regulation of purine nucleotide metabolic processGO:19005421150.016
carbohydrate derivative biosynthetic processGO:19011371240.016
cellular response to organonitrogen compoundGO:00714171970.016
muscle system processGO:00030121150.016
brain developmentGO:00074202470.016
cellular calcium ion homeostasisGO:00068741600.016
cellular response to organic cyclic compoundGO:00714072020.016
response to ionizing radiationGO:0010212590.016
regulation of hormone levelsGO:00108171870.016
ribonucleoside metabolic processGO:00091191740.016
carbohydrate derivative catabolic processGO:19011361470.015
regulation of establishment of protein localizationGO:0070201690.015
positive regulation of neuron differentiationGO:00456661260.015
regulation of purine nucleotide biosynthetic processGO:1900371460.015
response to transition metal nanoparticleGO:19902671220.015
membrane organizationGO:0061024940.015
embryonic skeletal system developmentGO:004870630.015
cation homeostasisGO:00550801950.015
cell motilityGO:00488702020.015
inorganic ion transmembrane transportGO:00986602290.015
kidney developmentGO:0001822670.015
glycosyl compound metabolic processGO:19016571820.015
positive regulation of nucleoside metabolic processGO:0045979550.015
heart developmentGO:0007507720.015
lipid biosynthetic processGO:00086101280.015
head developmentGO:00603222470.015
positive regulation of phosphate metabolic processGO:00459372620.015
neuronal action potentialGO:0019228350.015
hormone secretionGO:00468791150.015
macromolecular complex assemblyGO:00650032730.015
positive regulation of cell developmentGO:00107201760.015
carbohydrate metabolic processGO:00059751300.015
negative regulation of molecular functionGO:00440921330.014
negative regulation of cell proliferationGO:00082851190.014
inorganic cation transmembrane transportGO:00986622020.014
peptide transportGO:0015833970.014
dna metabolic processGO:0006259960.014
negative regulation of neuron differentiationGO:0045665620.014
regulation of hormone secretionGO:00468831060.014
positive regulation of cellular amine metabolic processGO:003324030.014
positive regulation of blood circulationGO:1903524650.014
purine nucleotide biosynthetic processGO:0006164830.014
cyclic nucleotide biosynthetic processGO:0009190630.014
regulation of cell projection organizationGO:00313441750.014
response to peptideGO:19016522920.014
chromosome segregationGO:000705920.014
organ formationGO:004864530.014
cellular response to hormone stimulusGO:00328702470.014
actin cytoskeleton organizationGO:0030036730.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
renal system developmentGO:0072001670.014
cellular response to transforming growth factor beta stimulusGO:0071560410.014
regulation of locomotionGO:00400121480.014
gliogenesisGO:0042063930.014
negative regulation of programmed cell deathGO:00430691830.014
purine nucleotide metabolic processGO:00061632290.014
response to extracellular stimulusGO:00099913800.014
negative regulation of developmental processGO:00510931250.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
nucleotide biosynthetic processGO:0009165980.013
epithelium developmentGO:0060429960.013
biological adhesionGO:00226101100.013
organic hydroxy compound transportGO:0015850770.013
vitamin d biosynthetic processGO:004236820.013
negative regulation of rna biosynthetic processGO:19026791180.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
intracellular protein transportGO:0006886790.013
positive regulation of rna biosynthetic processGO:19026801970.013
anion transportGO:00068201780.013
organic cyclic compound catabolic processGO:19013611750.013
response to amino acidGO:0043200750.013
regulation of homotypic cell cell adhesionGO:003411040.013
purine ribonucleotide catabolic processGO:00091541360.013
nucleoside triphosphate metabolic processGO:00091411440.013
regulation of nucleotide metabolic processGO:00061401170.013
amide transportGO:00428861050.013
oxidation reduction processGO:00551143040.013
development of primary sexual characteristicsGO:00451371070.013
protein transportGO:00150311320.013
muscle contractionGO:0006936880.013
gonad developmentGO:00084061040.013
cellular lipid metabolic processGO:00442552080.013
purine nucleoside catabolic processGO:00061521240.012
metal ion homeostasisGO:00550651860.012
cellular metal ion homeostasisGO:00068751720.012
small molecule biosynthetic processGO:00442831240.012
purine containing compound catabolic processGO:00725231380.012
response to interleukin 1GO:0070555550.012
positive regulation of nucleotide catabolic processGO:0030813530.012
regulation of catabolic processGO:00098941130.012
signal releaseGO:00230611450.012
response to organophosphorusGO:00466831020.012
camp metabolic processGO:0046058630.012
metal ion transportGO:00300012890.012
regulation of nervous system developmentGO:00519602640.012
ion homeostasisGO:00508012120.012
regulation of cellular localizationGO:00603412630.012
axon developmentGO:0061564960.012
regulation of catecholamine secretionGO:0050433320.012
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.012
aromatic compound catabolic processGO:00194391680.012
negative regulation of rna metabolic processGO:00512531230.012
peptide hormone secretionGO:0030072840.012
regenerationGO:00310991630.012
negative regulation of neurogenesisGO:0050768780.012
positive regulation of catabolic processGO:0009896780.012
transcription dna templatedGO:00063513770.012
salivary gland developmentGO:000743130.012
gtp metabolic processGO:0046039720.012
rho protein signal transductionGO:0007266110.012
regulation of blood pressureGO:0008217830.012
organonitrogen compound catabolic processGO:19015651790.012
regulation of cell motilityGO:20001451310.012
carbohydrate catabolic processGO:0016052400.012
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.012
learning or memoryGO:0007611900.012
regulation of organ formationGO:000315620.012
carboxylic acid metabolic processGO:00197522890.011
negative regulation of cellular biosynthetic processGO:00313271610.011
cellular ion homeostasisGO:00068731840.011
regulation of nucleoside metabolic processGO:0009118660.011
saliva secretionGO:004654130.011
cyclic purine nucleotide metabolic processGO:0052652620.011
involuntary skeletal muscle contractionGO:000301120.011
cellular protein complex assemblyGO:0043623440.011
regulation of nucleotide biosynthetic processGO:0030808470.011
neurological system processGO:00508772190.011
camp biosynthetic processGO:0006171470.011
positive regulation of purine nucleotide catabolic processGO:0033123530.011
negative regulation of biosynthetic processGO:00098901680.011
positive regulation of the force of heart contraction by norepinephrineGO:000306110.011
circadian rhythmGO:0007623880.011
response to acid chemicalGO:00011012220.011
cognitionGO:0050890920.011
cell cycle checkpointGO:000007520.011
regulation of hydrolase activityGO:00513361430.011
purine ribonucleotide biosynthetic processGO:0009152810.011
regulation of nucleotide catabolic processGO:0030811650.011
proteolysisGO:00065081750.011
cytoplasmic transportGO:00164821150.011
positive regulation of renin secretion into blood streamGO:190013510.011
neuron neuron synaptic transmissionGO:0007270600.011
gland developmentGO:00487321550.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
regulation of intracellular signal transductionGO:19025312180.011
reproductive system developmentGO:00614581280.011
purine ribonucleoside catabolic processGO:00461301240.011
response to ethanolGO:00454711620.011
hematopoietic progenitor cell differentiationGO:000224420.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
positive regulation of intracellular signal transductionGO:19025331380.011
regulation of anatomical structure sizeGO:00900661350.011
exocytosisGO:0006887600.011
regulation of peptide transportGO:0090087870.011
positive regulation of nucleotide metabolic processGO:0045981910.011
catecholamine transportGO:0051937370.010
nucleobase containing compound catabolic processGO:00346551520.010
platelet aggregationGO:007052740.010
response to inorganic substanceGO:00100353770.010
regulation of cellular amine metabolic processGO:003323880.010
purine containing compound biosynthetic processGO:0072522850.010
negative regulation of transportGO:00510511360.010
regulation of cell adhesionGO:0030155520.010
positive regulation of apoptotic processGO:00430651540.010
cell morphogenesisGO:00009021420.010
regulation of body fluid levelsGO:0050878900.010
memoryGO:0007613540.010
regulation of ion transportGO:00432692450.010
response to peptide hormoneGO:00434342780.010
regulation of gluconeogenesisGO:000611140.010
potassium ion transportGO:0006813970.010
response to transforming growth factor betaGO:0071559460.010
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.010
negative regulation of nervous system developmentGO:0051961790.010
positive regulation of neurogenesisGO:00507691650.010
negative regulation of uterine smooth muscle contractionGO:007047320.010
cellular divalent inorganic cation homeostasisGO:00725031620.010
single organism intracellular transportGO:19025821660.010
tube developmentGO:0035295890.010
positive regulation of catalytic activityGO:00430851840.010
regulation of bmp signaling pathwayGO:003051020.010
carboxylic acid biosynthetic processGO:0046394830.010
regulation of signal transductionGO:00099663180.010

Cdkn2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.023
disease of metabolismDOID:001466700.023
disease of anatomical entityDOID:700.018
nervous system diseaseDOID:86300.018
sensory system diseaseDOID:005015500.011