Rattus norvegicus

29 known processes

Klf5

Kruppel-like factor 5

(Aliases: bteb2,IKLF,Bteb2)

Klf5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transcription dna templatedGO:00063553740.164
Human Rat
transcription dna templatedGO:00063513770.156
Human Rat
regulation of nucleic acid templated transcriptionGO:19035063800.133
Human Rat
regulation of programmed cell deathGO:00430673410.131
negative regulation of cellular metabolic processGO:00313242810.120
Rat
transcription from rna polymerase ii promoterGO:00063662520.118
Human Rat
regulation of rna metabolic processGO:00512523910.117
Human Rat
programmed cell deathGO:00125013920.117
rna biosynthetic processGO:00327743800.116
Human Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.114
Human Rat
rna metabolic processGO:00160704060.110
Human Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.100
Human Rat
regulation of apoptotic processGO:00429813350.099
regulation of phosphate metabolic processGO:00192203490.097
Rat
positive regulation of gene expressionGO:00106282440.094
Human Rat
apoptotic processGO:00069153810.084
nucleic acid templated transcriptionGO:00976593790.081
Human Rat
positive regulation of rna biosynthetic processGO:19026801970.071
Human Rat
negative regulation of cellular biosynthetic processGO:00313271610.071
Rat
negative regulation of macromolecule metabolic processGO:00106052600.071
Rat
regulation of rna biosynthetic processGO:20011413810.070
Human Rat
neuron differentiationGO:00301823680.070
regulation of molecular functionGO:00650093980.069
Rat
negative regulation of programmed cell deathGO:00430691830.067
negative regulation of metabolic processGO:00098923310.066
Rat
cellular response to endogenous stimulusGO:00714953770.066
multi organism reproductive processGO:00447032620.065
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.063
Rat
negative regulation of macromolecule biosynthetic processGO:00105581480.060
Rat
regulation of phosphorylationGO:00423252480.059
Rat
cell cell signalingGO:00072673350.059
positive regulation of biosynthetic processGO:00098913190.059
Human Rat
response to decreased oxygen levelsGO:00362932370.056
cellular component biogenesisGO:00440853680.054
positive regulation of transcription dna templatedGO:00458931970.054
Human Rat
negative regulation of rna metabolic processGO:00512531230.053
Rat
reproductive processGO:00224143720.053
negative regulation of nucleobase containing compound metabolic processGO:00459341530.053
Rat
anatomical structure morphogenesisGO:00096532980.052
regulation of cell differentiationGO:00455953200.051
regulation of system processGO:00440572080.051
Rat
cell projection organizationGO:00300303020.051
protein phosphorylationGO:00064683450.050
positive regulation of nucleobase containing compound metabolic processGO:00459353190.049
Human Rat
positive regulation of cellular biosynthetic processGO:00313282950.048
Human Rat
response to inorganic substanceGO:00100353770.047
Rat
response to peptideGO:19016522920.047
regulation of multicellular organismal developmentGO:20000263760.047
regulation of protein metabolic processGO:00512462890.047
negative regulation of apoptotic processGO:00430661810.046
positive regulation of molecular functionGO:00440932300.046
positive regulation of multicellular organismal processGO:00512403870.046
neuron developmentGO:00486662860.045
regulation of cell developmentGO:00602842630.045
regulation of protein modification processGO:00313991940.044
cytoskeleton organizationGO:00070101110.044
positive regulation of programmed cell deathGO:00430681570.044
negative regulation of biosynthetic processGO:00098901680.044
Rat
neuron projection morphogenesisGO:00488121220.043
regulation of cell proliferationGO:00421273590.043
neuron projection developmentGO:00311752730.043
macromolecular complex subunit organizationGO:00439333390.043
cellular response to hormone stimulusGO:00328702470.042
positive regulation of developmental processGO:00510942830.042
single organism reproductive processGO:00447022970.041
negative regulation of gene expressionGO:00106291990.041
Rat
positive regulation of nucleic acid templated transcriptionGO:19035081970.041
Human Rat
response to hydrogen peroxideGO:0042542890.040
Rat
cellular ketone metabolic processGO:0042180510.039
circulatory system processGO:00030131830.039
positive regulation of macromolecule biosynthetic processGO:00105572470.039
Human Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.039
Rat
regulation of cellular protein metabolic processGO:00322682670.038
response to peptide hormoneGO:00434342780.038
regulation of nervous system developmentGO:00519602640.038
protein complex subunit organizationGO:00718223020.038
regulation of phosphorus metabolic processGO:00511743490.037
Rat
cellular response to stressGO:00335542690.037
Rat
regulation of cellular amino acid metabolic processGO:000652120.036
regulation of catalytic activityGO:00507903040.036
Rat
mapk cascadeGO:00001651400.036
Rat
regulation of neurogenesisGO:00507672470.035
cellular response to oxygen containing compoundGO:19017013860.035
positive regulation of rna metabolic processGO:00512542030.035
Human Rat
single organism organelle organizationGO:19025891800.034
positive regulation of cell deathGO:00109421840.034
blood circulationGO:00080151830.034
cell morphogenesis involved in neuron differentiationGO:00486671060.034
negative regulation of cell proliferationGO:00082851190.034
Rat
multicellular organism reproductionGO:00325042330.033
negative regulation of nucleic acid templated transcriptionGO:19035071170.033
Rat
synaptic growth at neuromuscular junctionGO:005112410.033
nitrogen compound transportGO:00717052290.032
cation transportGO:00068123820.032
positive regulation of phosphate metabolic processGO:00459372620.031
regulation of neuron projection developmentGO:00109751610.031
multicellular organismal reproductive processGO:00486092330.031
brain developmentGO:00074202470.030
positive regulation of response to stimulusGO:00485842850.030
positive regulation of apoptotic processGO:00430651540.030
cellular component morphogenesisGO:00329891550.030
actin filament based processGO:0030029860.030
circulatory system developmentGO:00723591340.030
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.029
response to oxidative stressGO:00069791860.029
Rat
wound healingGO:00420601220.029
Rat
oxoacid metabolic processGO:00434362900.029
organelle organizationGO:00069962660.029
negative regulation of cell deathGO:00605482290.028
metal ion transportGO:00300012890.028
response to hypoxiaGO:00016662310.028
protein complex biogenesisGO:00702712630.028
organic acid metabolic processGO:00060822920.028
tissue developmentGO:00098882520.028
negative regulation of response to stimulusGO:00485851550.028
Rat
negative regulation of nervous system developmentGO:0051961790.028
cellular component assemblyGO:00226073600.028
central nervous system developmentGO:00074173110.028
cell morphogenesis involved in differentiationGO:00009041190.027
regulation of cell projection organizationGO:00313441750.027
positive regulation of neurogenesisGO:00507691650.027
locomotionGO:00400112370.027
response to metal ionGO:00100382530.027
sexual reproductionGO:00199531480.027
cell morphogenesisGO:00009021420.027
positive regulation of cell communicationGO:00106472710.027
transmembrane transportGO:00550854120.027
positive regulation of protein metabolic processGO:00512471780.026
negative regulation of transcription dna templatedGO:00458921160.026
Rat
cellular component movementGO:00069282480.026
response to purine containing compoundGO:00140741260.026
negative regulation of cell differentiationGO:0045596990.026
actin cytoskeleton organizationGO:0030036730.026
regulation of signal transductionGO:00099663180.026
Rat
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
Human Rat
regulation of cellular component organizationGO:00511283680.026
regulation of neuron differentiationGO:00456642080.026
cellular amine metabolic processGO:0044106380.026
single organism biosynthetic processGO:00447113420.026
positive regulation of cell differentiationGO:00455972170.025
negative regulation of molecular functionGO:00440921330.025
response to acid chemicalGO:00011012220.025
Rat
cell motilityGO:00488702020.025
regulation of transferase activityGO:00513381230.025
Rat
response to oxygen levelsGO:00704822650.024
negative regulation of cell communicationGO:00106481580.024
Rat
positive regulation of cellular component organizationGO:00511302000.024
cellular chemical homeostasisGO:00550822470.024
regulation of protein phosphorylationGO:00019321830.024
cell type specific apoptotic processGO:00972851340.024
intracellular signal transductionGO:00355563140.024
Rat
gamete generationGO:00072761240.024
organophosphate metabolic processGO:00196373700.024
Rat
agingGO:00075682410.024
response to estrogenGO:00436272320.024
negative regulation of developmental processGO:00510931250.024
cytosolic calcium ion homeostasisGO:00514801400.023
negative regulation of protein metabolic processGO:00512481140.023
localization of cellGO:00516742020.023
regulation of cellular amine metabolic processGO:003323880.023
cellular response to growth factor stimulusGO:00713631620.023
positive regulation of signalingGO:00230562700.023
positive regulation of transportGO:00510502450.023
response to woundingGO:00096112540.023
Rat
metal ion homeostasisGO:00550651860.023
response to corticosteroidGO:00319602350.023
neurological system processGO:00508772190.023
mesoderm developmentGO:000749820.023
formation of primary germ layerGO:000170410.023
response to glucocorticoidGO:00513842230.022
cell migrationGO:00164771970.022
response to reactive oxygen speciesGO:00003021200.022
Rat
reproductionGO:00000032450.022
cell growthGO:00160491040.022
negative regulation of cell developmentGO:0010721820.022
negative regulation of multicellular organismal processGO:00512412030.022
Rat
positive regulation of cell proliferationGO:00082842490.022
positive regulation of phosphorus metabolic processGO:00105622620.022
positive regulation of nervous system developmentGO:00519621780.022
cellular lipid metabolic processGO:00442552080.022
Rat
purine ribonucleotide metabolic processGO:00091502270.021
lipid metabolic processGO:00066292830.021
Rat
macromolecular complex assemblyGO:00650032730.021
negative regulation of neurogenesisGO:0050768780.021
homeostatic processGO:00425923310.021
multi multicellular organism processGO:00447061380.021
sensory organ developmentGO:0007423740.021
inorganic cation transmembrane transportGO:00986622020.021
catabolic processGO:00090563510.021
cell projection morphogenesisGO:00488581230.021
positive regulation of catalytic activityGO:00430851840.021
muscle system processGO:00030121150.021
Rat
negative regulation of phosphorus metabolic processGO:0010563800.020
Rat
cardiovascular system developmentGO:00723581340.020
muscle contractionGO:0006936880.020
gastrulationGO:000736920.020
growthGO:00400071650.020
intracellular transportGO:00469071850.020
regulation of cellular ketone metabolic processGO:0010565270.020
carboxylic acid metabolic processGO:00197522890.020
response to extracellular stimulusGO:00099913800.020
response to ketoneGO:19016541820.020
heart morphogenesisGO:000300730.020
single organism behaviorGO:00447081300.020
amine metabolic processGO:0009308380.020
protein complex assemblyGO:00064612630.020
developmental process involved in reproductionGO:00030061590.019
female pregnancyGO:00075651220.019
gland developmentGO:00487321550.019
response to alkaloidGO:00432791320.019
axon developmentGO:0061564960.019
salivary gland morphogenesisGO:000743510.019
regulation of cellular component movementGO:00512701500.019
immune responseGO:00069551040.019
immune system processGO:00023762040.019
cellular amino acid metabolic processGO:00065201070.019
regulation of cellular localizationGO:00603412630.019
negative regulation of cellular protein metabolic processGO:00322691060.019
positive regulation of cell projection organizationGO:00313461110.019
carbohydrate derivative metabolic processGO:19011353460.019
negative regulation of phosphate metabolic processGO:0045936800.019
Rat
chemical homeostasisGO:00488782920.019
axis specificationGO:000979840.018
cellular protein localizationGO:00346131220.018
synaptic transmissionGO:00072682350.018
regulation of growthGO:00400081050.018
regulation of secretionGO:00510462240.018
regulation of membrane potentialGO:00423911100.018
positive regulation of protein modification processGO:00314011420.018
response to molecule of bacterial originGO:00022371940.018
positive regulation of cellular protein metabolic processGO:00322701670.018
positive regulation of cellular amine metabolic processGO:003324030.018
secretionGO:00469033070.018
cation transmembrane transportGO:00986552630.018
response to growth factorGO:00708481890.018
dephosphorylationGO:0016311980.018
signal transduction by phosphorylationGO:00230141440.018
Rat
regulation of cell growthGO:0001558850.018
ion transmembrane transportGO:00342203650.017
regulation of cellular component biogenesisGO:0044087860.017
epithelium developmentGO:0060429960.017
response to bacteriumGO:00096172000.017
cellular response to lipidGO:00713962010.017
Rat
cell part morphogenesisGO:00329901230.017
head developmentGO:00603222470.017
divalent inorganic cation transportGO:00725111340.017
cellular calcium ion homeostasisGO:00068741600.017
dna metabolic processGO:0006259960.017
regulation of protein kinase activityGO:00458591050.016
protein oligomerizationGO:00512591910.016
axonogenesisGO:0007409710.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
nucleotide metabolic processGO:00091172790.016
response to cytokineGO:00340972150.016
Rat
nucleoside phosphate metabolic processGO:00067532830.016
nucleobase containing small molecule metabolic processGO:00550863160.016
negative regulation of neuron differentiationGO:0045665620.016
response to organophosphorusGO:00466831020.016
anterior posterior pattern specificationGO:000995210.016
regulation of anatomical structure sizeGO:00900661350.016
regulation of canonical wnt signaling pathwayGO:006082840.016
response to toxic substanceGO:00096361330.016
ras protein signal transductionGO:0007265290.016
purine ribonucleoside metabolic processGO:00461281680.016
response to biotic stimulusGO:00096072260.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
negative regulation of catalytic activityGO:00430861030.015
oxidation reduction processGO:00551143040.015
positive regulation of cell developmentGO:00107201760.015
inorganic ion transmembrane transportGO:00986602290.015
negative regulation of rna biosynthetic processGO:19026791180.015
Rat
divalent inorganic cation homeostasisGO:00725071650.015
protein heterooligomerizationGO:0051291890.015
regulation of hydrolase activityGO:00513361430.015
ribose phosphate metabolic processGO:00196932350.015
regulation of cell motilityGO:20001451310.015
cellular macromolecule localizationGO:00707271220.015
response to mechanical stimulusGO:00096121340.015
developmental growthGO:00485891000.015
positive regulation of phosphorylationGO:00423271770.015
cellular ion homeostasisGO:00068731840.015
regulation of blood pressureGO:0008217830.015
single organism intracellular transportGO:19025821660.015
spermatogenesisGO:0007283990.015
purine nucleotide metabolic processGO:00061632290.015
positive regulation of cellular amino acid metabolic processGO:004576410.014
reproductive system developmentGO:00614581280.014
proteolysisGO:00065081750.014
protein transportGO:00150311320.014
regulation of protein serine threonine kinase activityGO:0071900640.014
positive regulation of neuron differentiationGO:00456661260.014
regulation of kinase activityGO:00435491170.014
Rat
ribonucleotide catabolic processGO:00092611360.014
ribonucleotide metabolic processGO:00092592310.014
negative regulation of signalingGO:00230571570.014
Rat
cellular homeostasisGO:00197252520.014
chemosensory behaviorGO:000763520.014
macromolecule localizationGO:00330362520.014
cellular response to organic cyclic compoundGO:00714072020.014
salivary gland developmentGO:000743130.014
signal releaseGO:00230611450.014
cell cycleGO:00070491010.014
response to external biotic stimulusGO:00432072210.014
male gamete generationGO:0048232990.013
response to other organismGO:00517072200.013
secretion by cellGO:00329402480.013
single organism catabolic processGO:00447122830.013
cellular response to peptide hormone stimulusGO:00713751200.013
behaviorGO:00076102050.013
response to monosaccharideGO:00342841590.013
organic substance catabolic processGO:19015753160.013
organic cyclic compound catabolic processGO:19013611750.013
cellular response to nitrogen compoundGO:19016992100.013
lipid biosynthetic processGO:00086101280.013
sequestering of calcium ionGO:005120880.013
ion homeostasisGO:00508012120.013
regulation of mapk cascadeGO:00434081160.013
Rat
calcium ion homeostasisGO:00550741620.013
nucleoside metabolic processGO:00091161790.013
heart contractionGO:0060047570.013
positive regulation of neuron projection developmentGO:0010976990.013
positive regulation of mapk cascadeGO:0043410920.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
small gtpase mediated signal transductionGO:0007264360.013
response to glucoseGO:00097491360.013
cytoplasmic transportGO:00164821150.013
cellular response to insulin stimulusGO:0032869810.013
muscle structure developmentGO:0061061870.013
synapse organizationGO:0050808460.013
neuron deathGO:00709971270.013
response to campGO:0051591910.013
negative regulation of protein phosphorylationGO:0001933440.013
response to lipopolysaccharideGO:00324961910.013
protein localizationGO:00081041910.012
positive regulation of cell migrationGO:0030335960.012
neuron apoptotic processGO:0051402880.012
g protein coupled receptor signaling pathwayGO:00071862420.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
positive regulation of secretion by cellGO:19035321280.012
regulation of cell migrationGO:00303341280.012
positive regulation of signal transductionGO:00099671750.012
epithelial cell differentiationGO:0030855710.012
actin filament organizationGO:0007015420.012
embryonic pattern specificationGO:000988010.012
neuronal action potentialGO:0019228350.012
erythrocyte differentiationGO:003021810.012
forebrain developmentGO:0030900980.012
cellular cation homeostasisGO:00300031800.012
heart developmentGO:0007507720.012
cellular nitrogen compound catabolic processGO:00442701630.012
negative regulation of protein modification processGO:0031400520.012
intracellular protein transportGO:0006886790.012
rhythmic processGO:00485111560.012
organonitrogen compound catabolic processGO:19015651790.012
glycosyl compound metabolic processGO:19016571820.012
regulation of neuron apoptotic processGO:0043523830.012
purine containing compound metabolic processGO:00725212530.012
organic hydroxy compound metabolic processGO:19016151150.012
positive regulation of protein phosphorylationGO:00019341350.012
cation homeostasisGO:00550801950.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.012
regulation of stem cell differentiationGO:200073620.012
negative regulation of transportGO:00510511360.012
nucleobase containing compound catabolic processGO:00346551520.011
purine nucleoside metabolic processGO:00422781690.011
neural crest cell developmentGO:001403220.011
cardiac muscle contractionGO:0060048270.011
organophosphate biosynthetic processGO:00904071430.011
motor neuron axon guidanceGO:000804510.011
protein processingGO:0016485680.011
neural crest cell differentiationGO:001403320.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
protein homooligomerizationGO:0051260910.011
muscle cell proliferationGO:0033002840.011
Rat
regulation of smooth muscle cell proliferationGO:0048660750.011
Rat
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
negative regulation of signal transductionGO:0009968830.011
Rat
negative regulation of osteoblast differentiationGO:004566820.011
regulation of fat cell differentiationGO:004559830.011
organ formationGO:004864530.011
single organism carbohydrate metabolic processGO:00447231180.011
regulation of tube sizeGO:0035150890.011
cellular carbohydrate metabolic processGO:0044262720.011
reactive oxygen species biosynthetic processGO:190340980.011
regulation of hormone secretionGO:00468831060.011
organ morphogenesisGO:0009887750.011
carbohydrate derivative catabolic processGO:19011361470.011
positive regulation of blood circulationGO:1903524650.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
regulation of secretion by cellGO:19035302080.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
reactive nitrogen species metabolic processGO:200105710.011
negative regulation of neuron deathGO:1901215690.011
response to nutrient levelsGO:00316673700.011
heart processGO:0003015570.011
positive regulation of transferase activityGO:0051347810.011
nucleoside phosphate catabolic processGO:19012921400.011
response to progesteroneGO:0032570480.011
heart valve morphogenesisGO:000317910.011
regulation of blood vessel sizeGO:0050880890.010
eye morphogenesisGO:004859240.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
rho protein signal transductionGO:0007266110.010
regenerationGO:00310991630.010
action potentialGO:0001508540.010
embryonic skeletal system developmentGO:004870630.010
regulation of catabolic processGO:00098941130.010
negative regulation of cellular component organizationGO:0051129830.010
regulation of embryonic developmentGO:004599520.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
single organism cellular localizationGO:19025801020.010
positive regulation of kinase activityGO:0033674770.010
response to estradiolGO:00323551640.010
regulation of organelle organizationGO:0033043800.010
striated muscle contractionGO:0006941440.010
inner ear morphogenesisGO:004247210.010
gonad developmentGO:00084061040.010
regulation of sequence specific dna binding transcription factor activityGO:0051090350.010
calcium ion transportGO:00068161310.010
regulation of mesenchymal cell proliferationGO:001046440.010
small molecule biosynthetic processGO:00442831240.010
positive regulation of catabolic processGO:0009896780.010
response to transforming growth factor betaGO:0071559460.010

Klf5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
central nervous system diseaseDOID:33100.013
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.011
musculoskeletal system diseaseDOID:1700.011