| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.138 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.116 | |
| aging | GO:0007568 | 241 | 0.104 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.095 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.088 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.075 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.070 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.070 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 2 | 0.069 | |
| immune system process | GO:0002376 | 204 | 0.068 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.066 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.064 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.059 | |
| negative regulation of protein metabolic process | GO:0051248 | 114 | 0.059 | |
| immune response | GO:0006955 | 104 | 0.058 | |
| transcription dna templated | GO:0006351 | 377 | 0.055 | |
| homeostatic process | GO:0042592 | 331 | 0.055 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.054 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.053 | |
| reproductive process | GO:0022414 | 372 | 0.051 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.049 | |
| protein dephosphorylation | GO:0006470 | 38 | 0.048 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.047 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.046 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.045 | |
| neuron differentiation | GO:0030182 | 368 | 0.045 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.044 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.042 | |
| protein phosphorylation | GO:0006468 | 345 | 0.040 | |
| regulation of molecular function | GO:0065009 | 398 | 0.039 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 106 | 0.039 | |
| positive regulation of signaling | GO:0023056 | 270 | 0.039 | |
| neurological system process | GO:0050877 | 219 | 0.038 | |
| regulation of jnk cascade | GO:0046328 | 19 | 0.036 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 35 | 0.036 | |
| axonogenesis | GO:0007409 | 71 | 0.036 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.035 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.035 | |
| neuron projection development | GO:0031175 | 273 | 0.034 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.034 | |
| secretion by cell | GO:0032940 | 248 | 0.033 | |
| behavior | GO:0007610 | 205 | 0.033 | |
| cell part morphogenesis | GO:0032990 | 123 | 0.033 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.033 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.033 | |
| neuron projection morphogenesis | GO:0048812 | 122 | 0.033 | |
| programmed cell death | GO:0012501 | 392 | 0.032 | |
| defense response | GO:0006952 | 194 | 0.032 | |
| organelle organization | GO:0006996 | 266 | 0.032 | |
| response to toxic substance | GO:0009636 | 133 | 0.031 | |
| cell growth | GO:0016049 | 104 | 0.030 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 141 | 0.030 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 116 | 0.030 | |
| protein localization to organelle | GO:0033365 | 57 | 0.029 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.029 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 119 | 0.029 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.029 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.028 | |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 8 | 0.028 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.028 | |
| single organism organelle organization | GO:1902589 | 180 | 0.027 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.027 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.027 | |
| cell morphogenesis involved in neuron differentiation | GO:0048667 | 106 | 0.027 | |
| single organism behavior | GO:0044708 | 130 | 0.027 | |
| cellular response to peptide | GO:1901653 | 133 | 0.027 | |
| cognition | GO:0050890 | 92 | 0.027 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.026 | |
| dephosphorylation | GO:0016311 | 98 | 0.026 | |
| response to inorganic substance | GO:0010035 | 377 | 0.026 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.026 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.025 | |
| peptidyl amino acid modification | GO:0018193 | 126 | 0.025 | |
| response to ethanol | GO:0045471 | 162 | 0.025 | |
| neuron death | GO:0070997 | 127 | 0.025 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.025 | |
| single organism reproductive process | GO:0044702 | 297 | 0.025 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.025 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.025 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.024 | |
| biological adhesion | GO:0022610 | 110 | 0.024 | |
| response to other organism | GO:0051707 | 220 | 0.024 | |
| response to corticosteroid | GO:0031960 | 235 | 0.024 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.024 | |
| axon development | GO:0061564 | 96 | 0.024 | |
| cellular component morphogenesis | GO:0032989 | 155 | 0.024 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.024 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.023 | |
| rna metabolic process | GO:0016070 | 406 | 0.023 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.023 | |
| multi multicellular organism process | GO:0044706 | 138 | 0.023 | |
| response to wounding | GO:0009611 | 254 | 0.023 | |
| cell type specific apoptotic process | GO:0097285 | 134 | 0.022 | |
| learning or memory | GO:0007611 | 90 | 0.022 | |
| neuron development | GO:0048666 | 286 | 0.022 | |
| regulation of kinase activity | GO:0043549 | 117 | 0.022 | |
| regulation of catabolic process | GO:0009894 | 113 | 0.022 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 80 | 0.022 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.022 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.022 | |
| response to biotic stimulus | GO:0009607 | 226 | 0.022 | |
| mapk cascade | GO:0000165 | 140 | 0.022 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.022 | |
| cellular protein localization | GO:0034613 | 122 | 0.021 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.021 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.021 | |
| response to growth factor | GO:0070848 | 189 | 0.021 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.020 | |
| ion homeostasis | GO:0050801 | 212 | 0.020 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.020 | |
| reproduction | GO:0000003 | 245 | 0.020 | |
| cation transport | GO:0006812 | 382 | 0.019 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.019 | |
| regulation of protein localization | GO:0032880 | 81 | 0.019 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.019 | |
| positive regulation of growth | GO:0045927 | 55 | 0.019 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.019 | |
| cellular ion homeostasis | GO:0006873 | 184 | 0.019 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.019 | |
| amine metabolic process | GO:0009308 | 38 | 0.019 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 242 | 0.019 | |
| regulation of organelle organization | GO:0033043 | 80 | 0.019 | |
| positive regulation of secretion | GO:0051047 | 140 | 0.018 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.018 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.018 | |
| regulation of neuron death | GO:1901214 | 115 | 0.018 | |
| cellular component assembly | GO:0022607 | 360 | 0.018 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.018 | |
| positive regulation of transport | GO:0051050 | 245 | 0.018 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.018 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.018 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.018 | |
| negative regulation of molecular function | GO:0044092 | 133 | 0.018 | |
| cell morphogenesis | GO:0000902 | 142 | 0.018 | |
| negative regulation of cellular component organization | GO:0051129 | 83 | 0.018 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.017 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.017 | |
| central nervous system development | GO:0007417 | 311 | 0.017 | |
| cellular response to stress | GO:0033554 | 269 | 0.017 | |
| membrane organization | GO:0061024 | 94 | 0.017 | |
| growth | GO:0040007 | 165 | 0.017 | |
| secretion | GO:0046903 | 307 | 0.017 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.017 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 10 | 0.017 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.017 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 80 | 0.017 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.017 | |
| response to radiation | GO:0009314 | 137 | 0.016 | |
| regulation of stress activated mapk cascade | GO:0032872 | 23 | 0.016 | |
| proteolysis | GO:0006508 | 175 | 0.016 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.016 | |
| immune effector process | GO:0002252 | 53 | 0.016 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.016 | |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 23 | 0.016 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 162 | 0.016 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.016 | |
| head development | GO:0060322 | 247 | 0.016 | |
| cellular macromolecule localization | GO:0070727 | 122 | 0.016 | |
| positive regulation of cell death | GO:0010942 | 184 | 0.015 | |
| cell projection morphogenesis | GO:0048858 | 123 | 0.015 | |
| ras protein signal transduction | GO:0007265 | 29 | 0.015 | |
| muscle system process | GO:0003012 | 115 | 0.015 | |
| cellular response to growth factor stimulus | GO:0071363 | 162 | 0.015 | |
| regeneration | GO:0031099 | 163 | 0.015 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.015 | |
| muscle structure development | GO:0061061 | 87 | 0.015 | |
| negative regulation of stress activated protein kinase signaling cascade | GO:0070303 | 4 | 0.015 | |
| chemical homeostasis | GO:0048878 | 292 | 0.015 | |
| cellular lipid metabolic process | GO:0044255 | 208 | 0.014 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 37 | 0.014 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.014 | |
| chromosome segregation | GO:0007059 | 2 | 0.014 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.014 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.014 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.014 | |
| salivary gland development | GO:0007431 | 3 | 0.014 | |
| response to oxidative stress | GO:0006979 | 186 | 0.014 | |
| positive regulation of protein modification process | GO:0031401 | 142 | 0.014 | |
| cell projection organization | GO:0030030 | 302 | 0.013 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.013 | |
| response to estrogen | GO:0043627 | 232 | 0.013 | |
| regulation of cell morphogenesis | GO:0022604 | 77 | 0.013 | |
| positive regulation of secretion by cell | GO:1903532 | 128 | 0.013 | |
| metal ion transport | GO:0030001 | 289 | 0.013 | |
| protein localization | GO:0008104 | 191 | 0.013 | |
| neuron apoptotic process | GO:0051402 | 88 | 0.013 | |
| embryonic pattern specification | GO:0009880 | 1 | 0.013 | |
| epithelial cell proliferation | GO:0050673 | 54 | 0.013 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.013 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.013 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.013 | |
| brain development | GO:0007420 | 247 | 0.013 | |
| sexual reproduction | GO:0019953 | 148 | 0.013 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.013 | |
| stress activated mapk cascade | GO:0051403 | 35 | 0.013 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 1 | 0.013 | |
| reproductive structure development | GO:0048608 | 128 | 0.013 | |
| divalent inorganic cation homeostasis | GO:0072507 | 165 | 0.012 | |
| positive regulation of programmed cell death | GO:0043068 | 157 | 0.012 | |
| regulation of protein kinase activity | GO:0045859 | 105 | 0.012 | |
| cell activation | GO:0001775 | 97 | 0.012 | |
| cation homeostasis | GO:0055080 | 195 | 0.012 | |
| negative regulation of signal transduction | GO:0009968 | 83 | 0.012 | |
| response to insulin | GO:0032868 | 133 | 0.012 | |
| positive regulation of transcription factor import into nucleus | GO:0042993 | 4 | 0.012 | |
| negative regulation of cell differentiation | GO:0045596 | 99 | 0.012 | |
| metal ion homeostasis | GO:0055065 | 186 | 0.012 | |
| response to peptide | GO:1901652 | 292 | 0.012 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.012 | |
| smad protein complex assembly | GO:0007183 | 1 | 0.012 | |
| tissue development | GO:0009888 | 252 | 0.012 | |
| amine transport | GO:0015837 | 57 | 0.012 | |
| motor neuron axon guidance | GO:0008045 | 1 | 0.012 | |
| catabolic process | GO:0009056 | 351 | 0.012 | |
| female pregnancy | GO:0007565 | 122 | 0.012 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.012 | |
| negative regulation of protein modification process | GO:0031400 | 52 | 0.012 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.012 | |
| circulatory system development | GO:0072359 | 134 | 0.012 | |
| regulation of growth | GO:0040008 | 105 | 0.012 | |
| regulation of epithelial cell proliferation | GO:0050678 | 49 | 0.012 | |
| response to cytokine | GO:0034097 | 215 | 0.012 | |
| regulation of anatomical structure size | GO:0090066 | 135 | 0.012 | |
| regulation of intracellular protein transport | GO:0033157 | 34 | 0.012 | |
| jnk cascade | GO:0007254 | 28 | 0.012 | |
| lipid metabolic process | GO:0006629 | 283 | 0.012 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.012 | |
| mast cell chemotaxis | GO:0002551 | 4 | 0.011 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.011 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.011 | |
| negative regulation of transforming growth factor beta receptor signaling pathway | GO:0030512 | 2 | 0.011 | |
| intracellular transport | GO:0046907 | 185 | 0.011 | |
| regulation of neuron apoptotic process | GO:0043523 | 83 | 0.011 | |
| taxis | GO:0042330 | 67 | 0.011 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.011 | |
| inflammatory response | GO:0006954 | 150 | 0.011 | |
| regulation of secretion by cell | GO:1903530 | 208 | 0.011 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.011 | |
| protein transport | GO:0015031 | 132 | 0.011 | |
| jak stat cascade | GO:0007259 | 26 | 0.011 | |
| negative regulation of jnk cascade | GO:0046329 | 4 | 0.011 | |
| development of primary sexual characteristics | GO:0045137 | 107 | 0.011 | |
| positive regulation of cell differentiation | GO:0045597 | 217 | 0.011 | |
| transmembrane transport | GO:0055085 | 412 | 0.011 | |
| synaptic growth at neuromuscular junction | GO:0051124 | 1 | 0.011 | |
| regulation of ion transport | GO:0043269 | 245 | 0.011 | |
| response to peptide hormone | GO:0043434 | 278 | 0.011 | |
| regulation of cell development | GO:0060284 | 263 | 0.011 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.011 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.011 | |
| exocytosis | GO:0006887 | 60 | 0.011 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.011 | |
| lipid transport | GO:0006869 | 61 | 0.010 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.010 | |
| gamete generation | GO:0007276 | 124 | 0.010 | |
| negative regulation of cell development | GO:0010721 | 82 | 0.010 | |
| apoptotic process | GO:0006915 | 381 | 0.010 | |
| cellular catabolic process | GO:0044248 | 295 | 0.010 | |
| regulation of cell growth | GO:0001558 | 85 | 0.010 | |
| response to ketone | GO:1901654 | 182 | 0.010 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.010 | |
| response to external biotic stimulus | GO:0043207 | 221 | 0.010 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 27 | 0.010 | |
| regulation of intracellular transport | GO:0032386 | 65 | 0.010 | |
| response to reactive oxygen species | GO:0000302 | 120 | 0.010 | |
| positive regulation of mapk cascade | GO:0043410 | 92 | 0.010 | |
