Rattus norvegicus

0 known processes

Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

(Aliases: MGC72599)

Plekha4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.109
regulation of transcription dna templatedGO:00063553740.083
response to inorganic substanceGO:00100353770.061
programmed cell deathGO:00125013920.060
rna biosynthetic processGO:00327743800.059
negative regulation of cell deathGO:00605482290.058
regulation of programmed cell deathGO:00430673410.054
rna metabolic processGO:00160704060.052
positive regulation of nitrogen compound metabolic processGO:00511733340.051
transcription dna templatedGO:00063513770.050
response to nutrient levelsGO:00316673700.047
transmembrane transportGO:00550854120.045
nucleic acid templated transcriptionGO:00976593790.045
cation transportGO:00068123820.044
regulation of rna metabolic processGO:00512523910.044
oxoacid metabolic processGO:00434362900.044
regulation of protein metabolic processGO:00512462890.044
response to peptide hormoneGO:00434342780.044
regulation of apoptotic processGO:00429813350.044
cellular response to oxygen containing compoundGO:19017013860.043
reproductive processGO:00224143720.043
carboxylic acid metabolic processGO:00197522890.042
transcription from rna polymerase ii promoterGO:00063662520.041
response to external biotic stimulusGO:00432072210.040
positive regulation of response to stimulusGO:00485842850.039
carbohydrate derivative metabolic processGO:19011353460.039
regulation of molecular functionGO:00650093980.039
chemical homeostasisGO:00488782920.038
regulation of cellular amine metabolic processGO:003323880.037
positive regulation of gene expressionGO:00106282440.037
regulation of cell proliferationGO:00421273590.037
single organism biosynthetic processGO:00447113420.037
response to lipopolysaccharideGO:00324961910.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
cell motilityGO:00488702020.035
cellular component movementGO:00069282480.034
regulation of cell differentiationGO:00455953200.034
regulation of rna biosynthetic processGO:20011413810.034
cellular amine metabolic processGO:0044106380.033
positive regulation of cell communicationGO:00106472710.033
single organism reproductive processGO:00447022970.033
response to extracellular stimulusGO:00099913800.033
cellular response to nitrogen compoundGO:19016992100.032
cellular chemical homeostasisGO:00550822470.032
amine metabolic processGO:0009308380.032
positive regulation of biosynthetic processGO:00098913190.032
regulation of nucleic acid templated transcriptionGO:19035063800.032
response to bacteriumGO:00096172000.032
cellular amino acid metabolic processGO:00065201070.031
response to estrogenGO:00436272320.031
homeostatic processGO:00425923310.031
regulation of phosphate metabolic processGO:00192203490.031
cellular response to peptide hormone stimulusGO:00713751200.031
response to glucocorticoidGO:00513842230.031
positive regulation of cellular biosynthetic processGO:00313282950.031
positive regulation of cell proliferationGO:00082842490.031
regulation of intracellular signal transductionGO:19025312180.031
regulation of signal transductionGO:00099663180.031
rhythmic processGO:00485111560.030
response to peptideGO:19016522920.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.030
organophosphate metabolic processGO:00196373700.030
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
positive regulation of intracellular signal transductionGO:19025331380.029
nucleoside phosphate metabolic processGO:00067532830.029
catabolic processGO:00090563510.028
cation homeostasisGO:00550801950.028
cellular response to hormone stimulusGO:00328702470.028
negative regulation of metabolic processGO:00098923310.028
response to carbohydrateGO:00097431830.028
secretion by cellGO:00329402480.028
regulation of catalytic activityGO:00507903040.028
ion homeostasisGO:00508012120.028
immune system processGO:00023762040.028
cellular catabolic processGO:00442482950.028
response to other organismGO:00517072200.027
cellular homeostasisGO:00197252520.027
response to biotic stimulusGO:00096072260.027
positive regulation of macromolecule biosynthetic processGO:00105572470.027
cellular cation homeostasisGO:00300031800.026
response to corticosteroidGO:00319602350.026
regulation of cellular amino acid metabolic processGO:000652120.026
regulation of cellular ketone metabolic processGO:0010565270.026
cellular ion homeostasisGO:00068731840.026
response to acid chemicalGO:00011012220.026
regulation of cellular component organizationGO:00511283680.026
protein phosphorylationGO:00064683450.026
positive regulation of developmental processGO:00510942830.026
response to radiationGO:00093141370.026
apoptotic processGO:00069153810.026
regulation of phosphorus metabolic processGO:00511743490.025
positive regulation of phosphorus metabolic processGO:00105622620.025
cellular component biogenesisGO:00440853680.025
cellular response to cytokine stimulusGO:00713451270.025
positive regulation of rna biosynthetic processGO:19026801970.025
localization of cellGO:00516742020.025
secretionGO:00469033070.025
cellular ketone metabolic processGO:0042180510.024
metal ion transportGO:00300012890.024
response to molecule of bacterial originGO:00022371940.024
lipid metabolic processGO:00066292830.024
regulation of response to stressGO:00801341260.023
cellular response to stressGO:00335542690.023
reproductionGO:00000032450.023
g protein coupled receptor signaling pathwayGO:00071862420.023
cell migrationGO:00164771970.023
response to insulinGO:00328681330.023
purine nucleotide metabolic processGO:00061632290.023
tissue developmentGO:00098882520.023
regulation of cellular protein metabolic processGO:00322682670.023
positive regulation of signalingGO:00230562700.023
cellular component assemblyGO:00226073600.023
inorganic ion transmembrane transportGO:00986602290.023
positive regulation of cell differentiationGO:00455972170.023
macromolecular complex subunit organizationGO:00439333390.023
divalent inorganic cation homeostasisGO:00725071650.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
agingGO:00075682410.022
organelle organizationGO:00069962660.022
negative regulation of programmed cell deathGO:00430691830.021
single organism catabolic processGO:00447122830.021
regulation of multicellular organismal developmentGO:20000263760.021
regulation of hormone levelsGO:00108171870.021
regulation of cellular component movementGO:00512701500.021
response to oxidative stressGO:00069791860.021
regulation of phosphorylationGO:00423252480.021
ion transmembrane transportGO:00342203650.021
regulation of immune system processGO:00026821230.021
cellular response to peptideGO:19016531330.021
negative regulation of cellular metabolic processGO:00313242810.021
response to growth factorGO:00708481890.020
regulation of protein modification processGO:00313991940.020
cation transmembrane transportGO:00986552630.020
positive regulation of transportGO:00510502450.020
macromolecular complex assemblyGO:00650032730.020
inorganic cation transmembrane transportGO:00986622020.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
response to cytokineGO:00340972150.020
locomotionGO:00400112370.020
macromolecule localizationGO:00330362520.020
ras protein signal transductionGO:0007265290.020
multicellular organism reproductionGO:00325042330.020
single organism intracellular transportGO:19025821660.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
positive regulation of phosphorylationGO:00423271770.019
defense responseGO:00069521940.019
intracellular transportGO:00469071850.019
neuron projection developmentGO:00311752730.019
metal ion homeostasisGO:00550651860.019
nucleotide metabolic processGO:00091172790.019
response to metal ionGO:00100382530.019
regulation of metal ion transportGO:00109591180.019
purine ribonucleotide metabolic processGO:00091502270.019
behaviorGO:00076102050.019
cellular response to endogenous stimulusGO:00714953770.019
response to nutrientGO:00075842480.019
single organism organelle organizationGO:19025891800.019
response to woundingGO:00096112540.019
cell projection organizationGO:00300303020.019
organic acid metabolic processGO:00060822920.018
regulation of cell developmentGO:00602842630.018
positive regulation of protein metabolic processGO:00512471780.018
monovalent inorganic cation transportGO:00156721720.018
enzyme linked receptor protein signaling pathwayGO:00071671160.018
cell cell signalingGO:00072673350.018
cellular lipid metabolic processGO:00442552080.018
central nervous system developmentGO:00074173110.018
glycosyl compound metabolic processGO:19016571820.018
response to ethanolGO:00454711620.018
cytosolic calcium ion homeostasisGO:00514801400.017
organic substance catabolic processGO:19015753160.017
wound healingGO:00420601220.017
positive regulation of signal transductionGO:00099671750.017
immune responseGO:00069551040.017
cellular calcium ion homeostasisGO:00068741600.017
regenerationGO:00310991630.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
positive regulation of cellular amine metabolic processGO:003324030.017
cellular response to organonitrogen compoundGO:00714171970.017
calcium ion homeostasisGO:00550741620.017
purine containing compound metabolic processGO:00725212530.016
positive regulation of cell developmentGO:00107201760.016
regulation of system processGO:00440572080.016
positive regulation of transcription dna templatedGO:00458931970.016
negative regulation of innate immune responseGO:004582440.016
divalent inorganic cation transportGO:00725111340.016
proteolysisGO:00065081750.016
positive regulation of nervous system developmentGO:00519621780.016
response to hexoseGO:00097461440.016
regulation of hormone secretionGO:00468831060.016
multicellular organismal reproductive processGO:00486092330.016
regulation of cell motilityGO:20001451310.016
nucleobase containing small molecule metabolic processGO:00550863160.016
negative regulation of macromolecule metabolic processGO:00106052600.016
carbohydrate derivative catabolic processGO:19011361470.016
anatomical structure morphogenesisGO:00096532980.016
regulation of response to external stimulusGO:00321011060.016
regulation of cellular localizationGO:00603412630.016
protein complex assemblyGO:00064612630.016
multi organism reproductive processGO:00447032620.015
nitrogen compound transportGO:00717052290.015
negative regulation of cellular biosynthetic processGO:00313271610.015
neuron differentiationGO:00301823680.015
protein complex subunit organizationGO:00718223020.015
vesicle mediated transportGO:00161921810.015
positive regulation of multicellular organismal processGO:00512403870.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
regulation of cell migrationGO:00303341280.015
amide transportGO:00428861050.015
positive regulation of cellular protein metabolic processGO:00322701670.015
cellular response to lipidGO:00713962010.015
neuron developmentGO:00486662860.015
ribose phosphate metabolic processGO:00196932350.015
negative regulation of secretionGO:0051048820.015
response to monosaccharideGO:00342841590.015
regulation of nervous system developmentGO:00519602640.015
positive regulation of phosphate metabolic processGO:00459372620.015
regulation of response to woundingGO:1903034690.014
positive regulation of molecular functionGO:00440932300.014
protein complex biogenesisGO:00702712630.014
aromatic compound catabolic processGO:00194391680.014
positive regulation of rna metabolic processGO:00512542030.014
response to glucoseGO:00097491360.014
positive regulation of cellular component organizationGO:00511302000.014
inflammatory responseGO:00069541500.014
negative regulation of gene expressionGO:00106291990.014
purine ribonucleoside catabolic processGO:00461301240.014
response to vitaminGO:00332731310.014
ribonucleotide metabolic processGO:00092592310.014
neurological system processGO:00508772190.014
regulation of ion transportGO:00432692450.014
sodium ion transportGO:0006814820.014
protein localizationGO:00081041910.014
negative regulation of rna metabolic processGO:00512531230.014
response to oxygen levelsGO:00704822650.014
blood vessel developmentGO:0001568690.014
regulation of locomotionGO:00400121480.014
cellular response to growth factor stimulusGO:00713631620.014
organophosphate biosynthetic processGO:00904071430.014
synaptic transmissionGO:00072682350.013
oxidation reduction processGO:00551143040.013
peptidyl tyrosine phosphorylationGO:0018108720.013
regulation of synaptic transmissionGO:00508041410.013
negative regulation of apoptotic processGO:00430661810.013
positive regulation of neuron differentiationGO:00456661260.013
signal releaseGO:00230611450.013
small gtpase mediated signal transductionGO:0007264360.013
positive regulation of neurogenesisGO:00507691650.013
regulation of protein phosphorylationGO:00019321830.013
regulation of anatomical structure morphogenesisGO:00226031410.013
ribonucleoside metabolic processGO:00091191740.013
regulation of purine nucleotide metabolic processGO:19005421150.013
regulation of defense responseGO:0031347680.013
cell activationGO:0001775970.013
regulation of secretionGO:00510462240.013
reproductive system developmentGO:00614581280.013
small molecule biosynthetic processGO:00442831240.013
cellular metal ion homeostasisGO:00068751720.012
positive regulation of nucleotide metabolic processGO:0045981910.012
actin filament based processGO:0030029860.012
nucleoside catabolic processGO:00091641260.012
regulation of cell morphogenesisGO:0022604770.012
regulation of neurogenesisGO:00507672470.012
cellular response to organic cyclic compoundGO:00714072020.012
hormone transportGO:00099141210.012
regulation of neuron projection developmentGO:00109751610.012
single organism behaviorGO:00447081300.012
sexual reproductionGO:00199531480.012
anion transportGO:00068201780.012
regulation of hydrolase activityGO:00513361430.012
positive regulation of cellular component movementGO:00512721020.012
gastrulationGO:000736920.012
protein oligomerizationGO:00512591910.012
regulation of membrane potentialGO:00423911100.012
positive regulation of programmed cell deathGO:00430681570.012
cellular nitrogen compound catabolic processGO:00442701630.012
negative regulation of transportGO:00510511360.012
b cell differentiationGO:003018320.012
eye morphogenesisGO:004859240.012
carbohydrate derivative biosynthetic processGO:19011371240.012
positive regulation of catalytic activityGO:00430851840.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
organic cyclic compound catabolic processGO:19013611750.012
response to ketoneGO:19016541820.012
negative regulation of response to stimulusGO:00485851550.012
negative regulation of cellular protein metabolic processGO:00322691060.011
positive regulation of protein modification processGO:00314011420.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
divalent metal ion transportGO:00708381320.011
organophosphate catabolic processGO:00464341480.011
neuronal action potentialGO:0019228350.011
negative regulation of transcription dna templatedGO:00458921160.011
development of primary female sexual characteristicsGO:0046545560.011
heterocycle catabolic processGO:00467001670.011
cellular response to insulin stimulusGO:0032869810.011
reproductive structure developmentGO:00486081280.011
axis specificationGO:000979840.011
cell morphogenesisGO:00009021420.011
purine ribonucleoside metabolic processGO:00461281680.011
nucleobase containing compound catabolic processGO:00346551520.011
mapk cascadeGO:00001651400.011
response to estradiolGO:00323551640.011
circulatory system processGO:00030131830.011
negative regulation of molecular functionGO:00440921330.011
glycosyl compound catabolic processGO:19016581260.011
purine containing compound catabolic processGO:00725231380.011
nucleoside triphosphate catabolic processGO:00091431230.011
establishment of protein localizationGO:00451841410.011
regulation of secretion by cellGO:19035302080.011
circulatory system developmentGO:00723591340.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
positive regulation of cell deathGO:00109421840.011
adult locomotory behaviorGO:000834440.011
multicellular organismal signalingGO:0035637440.011
skeletal system developmentGO:0001501410.011
ribonucleoside triphosphate metabolic processGO:00091991410.010
response to decreased oxygen levelsGO:00362932370.010
negative regulation of multicellular organismal processGO:00512412030.010
cellular component morphogenesisGO:00329891550.010
positive regulation of neuron projection developmentGO:0010976990.010
purine nucleoside catabolic processGO:00061521240.010
protein homooligomerizationGO:0051260910.010
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.010
purine ribonucleotide catabolic processGO:00091541360.010
regulation of nucleotide metabolic processGO:00061401170.010
ribonucleoside catabolic processGO:00424541260.010
organic anion transportGO:00157111320.010
membrane organizationGO:0061024940.010
nucleoside metabolic processGO:00091161790.010
carbohydrate metabolic processGO:00059751300.010
sodium ion transmembrane transportGO:0035725670.010
ossificationGO:0001503700.010
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.010
negative regulation of secretion by cellGO:1903531720.010

Plekha4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.024
disease of anatomical entityDOID:700.024
muscular diseaseDOID:008000000.020
myopathyDOID:42300.020
musculoskeletal system diseaseDOID:1700.020
muscle tissue diseaseDOID:6600.020
sensory system diseaseDOID:005015500.011
disease of metabolismDOID:001466700.010
eye and adnexa diseaseDOID:149200.010