Rattus norvegicus

159 known processes

Sema5a

sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Sema5a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of signal transductionGO:00099663180.094
intracellular signal transductionGO:00355563140.075
regulation of phosphorus metabolic processGO:00511743490.071
regulation of phosphate metabolic processGO:00192203490.070
protein phosphorylationGO:00064683450.070
cellular component movementGO:00069282480.062
cation transportGO:00068123820.059
regulation of phosphorylationGO:00423252480.057
divalent metal ion transportGO:00708381320.054
apoptotic processGO:00069153810.054
cellular component morphogenesisGO:00329891550.053
regulation of cellular protein metabolic processGO:00322682670.053
neuron differentiationGO:00301823680.050
positive regulation of phosphorylationGO:00423271770.050
positive regulation of phosphate metabolic processGO:00459372620.048
regulation of cellular component organizationGO:00511283680.047
regulation of cellular amine metabolic processGO:003323880.047
organic acid metabolic processGO:00060822920.044
regulation of cell differentiationGO:00455953200.043
regulation of cellular amino acid metabolic processGO:000652120.043
oxoacid metabolic processGO:00434362900.042
positive regulation of phosphorus metabolic processGO:00105622620.042
regulation of multicellular organismal developmentGO:20000263760.042
cellular amine metabolic processGO:0044106380.041
positive regulation of nitrogen compound metabolic processGO:00511733340.040
regulation of programmed cell deathGO:00430673410.039
cell projection morphogenesisGO:00488581230.039
cellular metal ion homeostasisGO:00068751720.039
regulation of canonical wnt signaling pathwayGO:006082840.038
positive regulation of cell communicationGO:00106472710.038
regulation of cell proliferationGO:00421273590.037
amine metabolic processGO:0009308380.037
cellular component biogenesisGO:00440853680.037
positive regulation of signal transductionGO:00099671750.037
g protein coupled receptor signaling pathwayGO:00071862420.037
programmed cell deathGO:00125013920.036
cell projection organizationGO:00300303020.036
cellular ketone metabolic processGO:0042180510.036
regulation of nervous system developmentGO:00519602640.036
regulation of protein modification processGO:00313991940.036
neuron projection developmentGO:00311752730.036
cell motilityGO:00488702020.035
regulation of neuron projection developmentGO:00109751610.035
calcium ion homeostasisGO:00550741620.035
positive regulation of cell migrationGO:0030335960.035
calcium ion transportGO:00068161310.035
cellular response to oxygen containing compoundGO:19017013860.035
cellular amino acid metabolic processGO:00065201070.034
ion homeostasisGO:00508012120.034
positive regulation of cell deathGO:00109421840.034
positive regulation of protein modification processGO:00314011420.034
positive regulation of signalingGO:00230562700.033
carboxylic acid metabolic processGO:00197522890.033
regulation of cell developmentGO:00602842630.033
cellular component assemblyGO:00226073600.033
single organism reproductive processGO:00447022970.032
positive regulation of response to stimulusGO:00485842850.032
biological adhesionGO:00226101100.032
central nervous system developmentGO:00074173110.032
metal ion homeostasisGO:00550651860.032
divalent inorganic cation homeostasisGO:00725071650.032
heart morphogenesisGO:000300730.031
negative regulation of canonical wnt signaling pathwayGO:009009040.031
regulation of protein metabolic processGO:00512462890.031
transmission of nerve impulseGO:0019226420.031
regulation of cellular ketone metabolic processGO:0010565270.031
negative regulation of cell proliferationGO:00082851190.031
positive regulation of multicellular organismal processGO:00512403870.030
anatomical structure morphogenesisGO:00096532980.030
rna biosynthetic processGO:00327743800.030
cell part morphogenesisGO:00329901230.030
neuron developmentGO:00486662860.030
regulation of neurogenesisGO:00507672470.030
negative regulation of cell communicationGO:00106481580.030
regulation of protein phosphorylationGO:00019321830.030
cytosolic calcium ion homeostasisGO:00514801400.030
regulation of cell morphogenesis involved in differentiationGO:0010769720.030
positive regulation of cell differentiationGO:00455972170.029
homeostatic processGO:00425923310.029
divalent inorganic cation transportGO:00725111340.029
transmembrane transportGO:00550854120.029
cell morphogenesisGO:00009021420.029
brain developmentGO:00074202470.028
response to nutrient levelsGO:00316673700.028
non canonical wnt signaling pathwayGO:003556730.028
chemical homeostasisGO:00488782920.028
positive regulation of molecular functionGO:00440932300.028
cellular ion homeostasisGO:00068731840.028
localization of cellGO:00516742020.028
positive regulation of developmental processGO:00510942830.027
reproductive processGO:00224143720.027
cell migrationGO:00164771970.027
organic substance catabolic processGO:19015753160.027
head developmentGO:00603222470.027
catabolic processGO:00090563510.027
cation homeostasisGO:00550801950.027
cellular cation homeostasisGO:00300031800.027
regulation of kinase activityGO:00435491170.027
positive regulation of gene expressionGO:00106282440.026
positive regulation of cytosolic calcium ion concentrationGO:00072041220.026
establishment of tissue polarityGO:000716420.026
locomotionGO:00400112370.026
response to peptideGO:19016522920.026
urogenital system developmentGO:0001655780.026
regulation of intracellular signal transductionGO:19025312180.026
regulation of neuron differentiationGO:00456642080.026
multicellular organismal reproductive processGO:00486092330.026
nucleobase containing small molecule metabolic processGO:00550863160.026
reproductionGO:00000032450.026
metal ion transportGO:00300012890.025
positive regulation of cellular amine metabolic processGO:003324030.025
cell adhesionGO:00071551100.025
cellular chemical homeostasisGO:00550822470.025
ribonucleotide metabolic processGO:00092592310.025
regulation of apoptotic processGO:00429813350.025
regulation of cell projection organizationGO:00313441750.025
negative regulation of gene expressionGO:00106291990.025
regulation of catalytic activityGO:00507903040.024
positive regulation of cell developmentGO:00107201760.024
small gtpase mediated signal transductionGO:0007264360.024
protein localizationGO:00081041910.024
axonogenesisGO:0007409710.024
regulation of molecular functionGO:00650093980.024
positive regulation of protein phosphorylationGO:00019341350.024
cell morphogenesis involved in neuron differentiationGO:00486671060.024
positive regulation of catalytic activityGO:00430851840.024
ion transmembrane transportGO:00342203650.024
positive regulation of cellular protein metabolic processGO:00322701670.023
mapk cascadeGO:00001651400.023
multi organism reproductive processGO:00447032620.023
carbohydrate derivative metabolic processGO:19011353460.023
wnt signaling pathway planar cell polarity pathwayGO:006007120.023
cellular response to lipidGO:00713962010.023
single organism intracellular transportGO:19025821660.023
synapse organizationGO:0050808460.023
inorganic cation transmembrane transportGO:00986622020.023
tissue developmentGO:00098882520.023
positive regulation of protein metabolic processGO:00512471780.023
positive regulation of cellular component organizationGO:00511302000.022
positive regulation of cellular amino acid metabolic processGO:004576410.022
negative regulation of metabolic processGO:00098923310.022
positive regulation of programmed cell deathGO:00430681570.022
positive regulation of locomotionGO:00400171020.022
regulation of anatomical structure morphogenesisGO:00226031410.022
response to inorganic substanceGO:00100353770.022
regenerationGO:00310991630.022
negative regulation of signalingGO:00230571570.021
positive regulation of neurogenesisGO:00507691650.021
response to extracellular stimulusGO:00099913800.021
regulation of membrane potentialGO:00423911100.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
positive regulation of cell proliferationGO:00082842490.021
single organism catabolic processGO:00447122830.021
signal transduction by phosphorylationGO:00230141440.021
positive regulation of nervous system developmentGO:00519621780.021
regulation of proteasomal protein catabolic processGO:006113640.020
negative regulation of cellular metabolic processGO:00313242810.020
motor neuron axon guidanceGO:000804510.020
negative regulation of multicellular organismal processGO:00512412030.020
positive regulation of biosynthetic processGO:00098913190.020
response to cytokineGO:00340972150.020
regulation of neuron deathGO:19012141150.020
cellular calcium ion homeostasisGO:00068741600.020
gastrulationGO:000736920.020
regulation of cellular component movementGO:00512701500.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
negative regulation of macromolecule metabolic processGO:00106052600.019
positive regulation of intracellular signal transductionGO:19025331380.019
cellular protein localizationGO:00346131220.019
cellular response to steroid hormone stimulusGO:0071383930.019
regulation of metal ion transportGO:00109591180.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
protein complex subunit organizationGO:00718223020.019
proteolysisGO:00065081750.019
regulation of cellular response to stressGO:0080135490.019
cellular response to endogenous stimulusGO:00714953770.019
nucleic acid templated transcriptionGO:00976593790.019
regulation of transcription dna templatedGO:00063553740.019
salivary gland developmentGO:000743130.018
regulation of establishment of planar polarityGO:009017520.018
regulation of ion transportGO:00432692450.018
regulation of cell morphogenesisGO:0022604770.018
taxisGO:0042330670.018
cellular response to stressGO:00335542690.018
regulation of cell growthGO:0001558850.018
protein oligomerizationGO:00512591910.018
sexual reproductionGO:00199531480.018
negative regulation of cell differentiationGO:0045596990.018
kidney developmentGO:0001822670.018
action potentialGO:0001508540.018
macromolecular complex assemblyGO:00650032730.018
positive regulation of cellular biosynthetic processGO:00313282950.018
positive regulation of cell motilityGO:2000147970.017
positive regulation of neuron projection developmentGO:0010976990.017
response to ethanolGO:00454711620.017
positive regulation of cell projection organizationGO:00313461110.017
macromolecule localizationGO:00330362520.017
response to metal ionGO:00100382530.017
macromolecular complex subunit organizationGO:00439333390.017
response to estradiolGO:00323551640.017
regulation of neuron apoptotic processGO:0043523830.016
regulation of transferase activityGO:00513381230.016
multicellular organism reproductionGO:00325042330.016
neurological system processGO:00508772190.016
purine containing compound metabolic processGO:00725212530.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
cellular macromolecule localizationGO:00707271220.016
circulatory system developmentGO:00723591340.016
neuronal action potentialGO:0019228350.016
nucleoside phosphate metabolic processGO:00067532830.016
response to glucocorticoidGO:00513842230.016
organic hydroxy compound metabolic processGO:19016151150.016
gliogenesisGO:0042063930.016
peptidyl amino acid modificationGO:00181931260.016
positive regulation of kinase activityGO:0033674770.016
nucleotide metabolic processGO:00091172790.016
cellular catabolic processGO:00442482950.016
muscle system processGO:00030121150.016
adult locomotory behaviorGO:000834440.016
cellular response to alcoholGO:0097306870.015
ras protein signal transductionGO:0007265290.015
transcription dna templatedGO:00063513770.015
secretionGO:00469033070.015
epithelium developmentGO:0060429960.015
organophosphate metabolic processGO:00196373700.015
organelle organizationGO:00069962660.015
synaptic growth at neuromuscular junctionGO:005112410.015
heart developmentGO:0007507720.015
regulation of mapk cascadeGO:00434081160.015
chromosome segregationGO:000705920.015
bmp signaling pathwayGO:003050940.015
establishment of planar polarityGO:000173610.015
protein complex biogenesisGO:00702712630.015
actin filament based processGO:0030029860.014
multicellular organismal signalingGO:0035637440.014
regulation of cellular localizationGO:00603412630.014
membrane organizationGO:0061024940.014
eye morphogenesisGO:004859240.014
cellular response to corticosteroid stimulusGO:0071384690.014
protein complex assemblyGO:00064612630.014
regulation of secretionGO:00510462240.014
immune responseGO:00069551040.014
regulation of response to stressGO:00801341260.014
regulation of stem cell differentiationGO:200073620.014
organonitrogen compound catabolic processGO:19015651790.014
axon developmentGO:0061564960.014
dendrite developmentGO:0016358720.014
cellular response to hormone stimulusGO:00328702470.014
positive regulation of neuron differentiationGO:00456661260.014
nucleobase containing compound catabolic processGO:00346551520.014
positive regulation of apoptotic processGO:00430651540.014
cell type specific apoptotic processGO:00972851340.014
circulatory system processGO:00030131830.014
cytoplasmic transportGO:00164821150.013
ribose phosphate metabolic processGO:00196932350.013
regulation of cell motilityGO:20001451310.013
negative regulation of developmental processGO:00510931250.013
axis specificationGO:000979840.013
single organism organelle organizationGO:19025891800.013
positive regulation of transferase activityGO:0051347810.013
regulation of locomotionGO:00400121480.013
response to peptide hormoneGO:00434342780.013
gland developmentGO:00487321550.013
cell cell signalingGO:00072673350.013
response to corticosteroidGO:00319602350.013
mesoderm developmentGO:000749820.013
regulation of rna metabolic processGO:00512523910.013
neuromuscular processGO:005090520.013
intracellular transportGO:00469071850.013
response to oxygen levelsGO:00704822650.013
tube developmentGO:0035295890.013
positive regulation of mapk cascadeGO:0043410920.013
organic cyclic compound catabolic processGO:19013611750.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
gamete generationGO:00072761240.013
regulation of anatomical structure sizeGO:00900661350.013
axon guidanceGO:0007411240.013
regulation of cell migrationGO:00303341280.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
negative regulation of cellular component organizationGO:0051129830.013
positive regulation of protein kinase activityGO:0045860730.013
regulation of fat cell differentiationGO:004559830.012
response to vitaminGO:00332731310.012
regulation of synaptic transmissionGO:00508041410.012
positive regulation of cellular component movementGO:00512721020.012
negative regulation of cell developmentGO:0010721820.012
carbohydrate metabolic processGO:00059751300.012
regulation of calcium ion transportGO:0051924770.012
organ formationGO:004864530.012
cell growthGO:00160491040.012
cellular response to cytokine stimulusGO:00713451270.012
axon midline choice point recognitionGO:001619920.012
chemotaxisGO:0006935660.012
growthGO:00400071650.012
aromatic compound catabolic processGO:00194391680.012
response to decreased oxygen levelsGO:00362932370.012
tissue morphogenesisGO:0048729220.012
rna metabolic processGO:00160704060.012
peptidyl tyrosine phosphorylationGO:0018108720.012
epithelial cell differentiationGO:0030855710.012
response to growth factorGO:00708481890.012
forebrain developmentGO:0030900980.012
positive regulation of nucleotide metabolic processGO:0045981910.012
positive regulation of ion transportGO:0043270940.012
regulation of hormone levelsGO:00108171870.012
response to lipopolysaccharideGO:00324961910.012
hair cycle processGO:002240520.011
formation of primary germ layerGO:000170410.011
morphogenesis of a polarized epitheliumGO:000173810.011
glycosyl compound metabolic processGO:19016571820.011
hair follicle developmentGO:000194220.011
establishment of protein localizationGO:00451841410.011
morphogenesis of embryonic epitheliumGO:001633130.011
single organism cell adhesionGO:0098602460.011
cardiac chamber developmentGO:000320510.011
response to radiationGO:00093141370.011
cytoskeleton organizationGO:00070101110.011
negative regulation of protein metabolic processGO:00512481140.011
negative regulation of molecular functionGO:00440921330.011
positive regulation of rna biosynthetic processGO:19026801970.011
negative regulation of neuron differentiationGO:0045665620.011
carbohydrate derivative catabolic processGO:19011361470.011
response to molecule of bacterial originGO:00022371940.011
neuron projection morphogenesisGO:00488121220.011
regulation of hydrolase activityGO:00513361430.011
anion transportGO:00068201780.011
protein heterooligomerizationGO:0051291890.011
male gamete generationGO:0048232990.011
spindle organizationGO:000705120.011
nucleotide catabolic processGO:00091661390.011
negative regulation of cell deathGO:00605482290.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
agingGO:00075682410.011
negative regulation of response to stimulusGO:00485851550.011
positive regulation of transportGO:00510502450.011
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.011
developmental process involved in reproductionGO:00030061590.011
neuron projection guidanceGO:0097485240.011
positive regulation of catabolic processGO:0009896780.011
peptidyl tyrosine modificationGO:0018212720.011
cerebral cortex cell migrationGO:002179540.011
reproductive structure developmentGO:00486081280.011
cellular response to glucocorticoid stimulusGO:0071385680.011
cell cycle checkpointGO:000007520.011
positive regulation of protein serine threonine kinase activityGO:0071902520.011
response to purine containing compoundGO:00140741260.011
regulation of bmp signaling pathwayGO:003051020.011
purine nucleotide metabolic processGO:00061632290.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
protein transportGO:00150311320.010
negative regulation of signal transductionGO:0009968830.010
synaptic transmissionGO:00072682350.010
negative regulation of nervous system developmentGO:0051961790.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
cellular nitrogen compound catabolic processGO:00442701630.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
neuron deathGO:00709971270.010
regulation of catabolic processGO:00098941130.010
response to carbohydrateGO:00097431830.010
regulation of ossificationGO:0030278320.010
carbohydrate derivative biosynthetic processGO:19011371240.010
spermatogenesisGO:0007283990.010
actin cytoskeleton organizationGO:0030036730.010
response to temperature stimulusGO:0009266940.010
cellular response to organic cyclic compoundGO:00714072020.010
inorganic ion transmembrane transportGO:00986602290.010
rhythmic processGO:00485111560.010
hair cycleGO:004263330.010
female sex differentiationGO:0046660590.010
response to hypoxiaGO:00016662310.010
activation of protein kinase activityGO:0032147470.010
cardiac ventricle developmentGO:000323110.010
cardiovascular system developmentGO:00723581340.010
cerebral cortex tangential migrationGO:002180010.010

Sema5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.012
central nervous system diseaseDOID:33100.012
organ system cancerDOID:005068600.011
urinary system diseaseDOID:1800.011