IMP: Integrative Multi-species Prediction

Rattus norvegicus

37 known processes

Cyp2j4

cytochrome P450, family 2, subfamily j, polypeptide 4

(Aliases: CYP2J2)

Entrez: 65210
RGD: 620007
Ensembl: ENSRNOG00000031004
UniProtKB: Q5BKA2

Process Predictions
Disease Predictions

Cyp2j4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
carboxylic acid metabolic process	GO:0019752	289	0.589
monocarboxylic acid metabolic process	GO:0032787	152	0.410
lipid metabolic process	GO:0006629	283	0.384
organic acid metabolic process	GO:0006082	292	0.376
fatty acid metabolic process	GO:0006631	99	0.322
oxoacid metabolic process	GO:0043436	290	0.292
cellular lipid metabolic process	GO:0044255	208	0.257
oxidation reduction process	GO:0055114	304	0.209
retinal metabolic process	GO:0042574	3	0.153
single organism biosynthetic process	GO:0044711	342	0.124
response to extracellular stimulus	GO:0009991	380	0.121
cellular catabolic process	GO:0044248	295	0.082
steroid metabolic process	GO:0008202	73	0.075
small molecule biosynthetic process	GO:0044283	124	0.071
gland development	GO:0048732	155	0.069	Rat
response to nutrient levels	GO:0031667	370	0.067
cellular component biogenesis	GO:0044085	368	0.067
cation transport	GO:0006812	382	0.065
transmembrane transport	GO:0055085	412	0.062
catabolic process	GO:0009056	351	0.062
homeostatic process	GO:0042592	331	0.060
central nervous system development	GO:0007417	311	0.060
protein complex subunit organization	GO:0071822	302	0.054
cellular response to nitrogen compound	GO:1901699	210	0.053
ion transmembrane transport	GO:0034220	365	0.053
monocarboxylic acid catabolic process	GO:0072329	28	0.053
response to peptide hormone	GO:0043434	278	0.052	Rat
nucleobase containing small molecule metabolic process	GO:0055086	316	0.050
lipid oxidation	GO:0034440	30	0.049
regulation of hormone levels	GO:0010817	187	0.048
protein complex assembly	GO:0006461	263	0.048
terpenoid metabolic process	GO:0006721	37	0.047
multicellular organismal reproductive process	GO:0048609	233	0.047
cellular component assembly	GO:0022607	360	0.046
cellular ketone metabolic process	GO:0042180	51	0.046
anion transport	GO:0006820	178	0.045
response to ketone	GO:1901654	182	0.044	Rat
head development	GO:0060322	247	0.044
organic acid biosynthetic process	GO:0016053	83	0.043
organic hydroxy compound metabolic process	GO:1901615	115	0.043	Rat
isoprenoid metabolic process	GO:0006720	45	0.041
multicellular organism reproduction	GO:0032504	233	0.041
liver development	GO:0001889	90	0.040	Rat
cellular response to organonitrogen compound	GO:0071417	197	0.040
fatty acid catabolic process	GO:0009062	26	0.039
macromolecular complex subunit organization	GO:0043933	339	0.039
inner medullary collecting duct development	GO:0072061	1	0.039
diterpenoid metabolic process	GO:0016101	33	0.038
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.038
unsaturated fatty acid metabolic process	GO:0033559	39	0.038
carbohydrate derivative metabolic process	GO:1901135	346	0.038
organelle organization	GO:0006996	266	0.037
response to oxidative stress	GO:0006979	186	0.037	Rat
nucleotide metabolic process	GO:0009117	279	0.037
small molecule catabolic process	GO:0044282	59	0.037
naphthalene metabolic process	GO:0018931	2	0.037	Rat
chemical homeostasis	GO:0048878	292	0.036
lipid biosynthetic process	GO:0008610	128	0.035
organic acid transport	GO:0015849	116	0.035
cellular response to external stimulus	GO:0071496	118	0.035
response to inorganic substance	GO:0010035	377	0.035	Rat
nucleoside phosphate metabolic process	GO:0006753	283	0.035
response to glucocorticoid	GO:0051384	223	0.034
protein complex biogenesis	GO:0070271	263	0.034
macromolecular complex assembly	GO:0065003	273	0.034
reproductive process	GO:0022414	372	0.033
linoleic acid metabolic process	GO:0043651	4	0.033	Human
response to peptide	GO:1901652	292	0.033	Rat
cellular response to lipid	GO:0071396	201	0.033
fatty acid derivative metabolic process	GO:1901568	38	0.032
response to metal ion	GO:0010038	253	0.032	Rat
carboxylic acid biosynthetic process	GO:0046394	83	0.032
regulation of cellular ketone metabolic process	GO:0010565	27	0.032
response to ethanol	GO:0045471	162	0.032	Rat
response to corticosteroid	GO:0031960	235	0.031
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.031
regulation of cell proliferation	GO:0042127	359	0.030
cellular response to oxygen containing compound	GO:1901701	386	0.029
cellular amine metabolic process	GO:0044106	38	0.029
protein homooligomerization	GO:0051260	91	0.029
single organism reproductive process	GO:0044702	297	0.029
alcohol metabolic process	GO:0006066	77	0.028
cellular response to stress	GO:0033554	269	0.028
single organism catabolic process	GO:0044712	283	0.028
cofactor metabolic process	GO:0051186	95	0.028
cellular response to hormone stimulus	GO:0032870	247	0.028
carboxylic acid transport	GO:0046942	115	0.027
organophosphate metabolic process	GO:0019637	370	0.027
organic anion transport	GO:0015711	132	0.027
neuron projection development	GO:0031175	273	0.027
purine containing compound metabolic process	GO:0072521	253	0.027
neuron differentiation	GO:0030182	368	0.027
dicarboxylic acid metabolic process	GO:0043648	42	0.026
multi organism reproductive process	GO:0044703	262	0.026
regulation of molecular function	GO:0065009	398	0.025
purine ribonucleotide metabolic process	GO:0009150	227	0.025
reproduction	GO:0000003	245	0.025
lipid catabolic process	GO:0016042	46	0.025
hormone metabolic process	GO:0042445	69	0.025
heterocycle catabolic process	GO:0046700	167	0.024
response to acid chemical	GO:0001101	222	0.024	Rat
cation transmembrane transport	GO:0098655	263	0.024
hepaticobiliary system development	GO:0061008	90	0.024	Rat
cellular hormone metabolic process	GO:0034754	49	0.024
olfactory learning	GO:0008355	1	0.024
benzene containing compound metabolic process	GO:0042537	22	0.024
ribonucleotide metabolic process	GO:0009259	231	0.024
response to bacterium	GO:0009617	200	0.024
drug catabolic process	GO:0042737	1	0.023
regulation of phosphate metabolic process	GO:0019220	349	0.023
brain development	GO:0007420	247	0.023
glycosyl compound metabolic process	GO:1901657	182	0.023
regulation of nervous system development	GO:0051960	264	0.023
cellular response to peptide hormone stimulus	GO:0071375	120	0.022
regulation of cellular amino acid metabolic process	GO:0006521	2	0.022
response to biotic stimulus	GO:0009607	226	0.022
response to carbohydrate	GO:0009743	183	0.022
organic substance catabolic process	GO:1901575	316	0.022
cellular amino acid metabolic process	GO:0006520	107	0.022
monocarboxylic acid biosynthetic process	GO:0072330	48	0.021
protein phosphorylation	GO:0006468	345	0.021
positive regulation of transport	GO:0051050	245	0.021
heart morphogenesis	GO:0003007	3	0.021
multi multicellular organism process	GO:0044706	138	0.020
amine metabolic process	GO:0009308	38	0.020
response to nutrient	GO:0007584	248	0.020
response to toxic substance	GO:0009636	133	0.020
inflammatory response	GO:0006954	150	0.019
developmental process involved in reproduction	GO:0003006	159	0.019
cellular homeostasis	GO:0019725	252	0.019
blood circulation	GO:0008015	183	0.019
cell projection organization	GO:0030030	302	0.019
lipid modification	GO:0030258	52	0.019
organic cyclic compound catabolic process	GO:1901361	175	0.019
positive regulation of nervous system development	GO:0051962	178	0.019
response to alkaloid	GO:0043279	132	0.019
response to monosaccharide	GO:0034284	159	0.019
purine nucleotide metabolic process	GO:0006163	229	0.019
response to estrogen	GO:0043627	232	0.019
regulation of apoptotic process	GO:0042981	335	0.019
response to decreased oxygen levels	GO:0036293	237	0.018
ribose phosphate metabolic process	GO:0019693	235	0.018
response to radiation	GO:0009314	137	0.018	Rat
biphenyl metabolic process	GO:0018879	10	0.018
anatomical structure morphogenesis	GO:0009653	298	0.018
regulation of programmed cell death	GO:0043067	341	0.018
steroid biosynthetic process	GO:0006694	48	0.018
positive regulation of cellular amine metabolic process	GO:0033240	3	0.018
cellular response to organic cyclic compound	GO:0071407	202	0.018
response to transition metal nanoparticle	GO:1990267	122	0.018
cellular lipid catabolic process	GO:0044242	37	0.018
telencephalon development	GO:0021537	62	0.018
response to wounding	GO:0009611	254	0.018
cellular response to endogenous stimulus	GO:0071495	377	0.018
regulation of ion transport	GO:0043269	245	0.018
regulation of signal transduction	GO:0009966	318	0.017
negative regulation of metabolic process	GO:0009892	331	0.017
positive regulation of cell death	GO:0010942	184	0.017
response to oxygen levels	GO:0070482	265	0.017
nucleoside metabolic process	GO:0009116	179	0.017
gliogenesis	GO:0042063	93	0.017
circulatory system process	GO:0003013	183	0.017
ribonucleoside metabolic process	GO:0009119	174	0.017
cellular chemical homeostasis	GO:0055082	247	0.017
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.017
regulation of cell development	GO:0060284	263	0.017
axis specification	GO:0009798	4	0.016
epithelial cell differentiation	GO:0030855	71	0.016
metal ion homeostasis	GO:0055065	186	0.016
neuron development	GO:0048666	286	0.016
regulation of catalytic activity	GO:0050790	304	0.016
sorbitol biosynthetic process	GO:0006061	1	0.016
tissue development	GO:0009888	252	0.016
exogenous drug catabolic process	GO:0042738	1	0.016
naphthalene containing compound metabolic process	GO:0090420	2	0.016	Rat
defense response	GO:0006952	194	0.016
neural crest cell differentiation	GO:0014033	2	0.016
ion homeostasis	GO:0050801	212	0.016
positive regulation of phosphorus metabolic process	GO:0010562	262	0.015
nucleic acid templated transcription	GO:0097659	379	0.015
amino acid transport	GO:0006865	70	0.015
organic hydroxy compound transport	GO:0015850	77	0.015
intracellular signal transduction	GO:0035556	314	0.015
single organism behavior	GO:0044708	130	0.015
intracellular transport	GO:0046907	185	0.015
response to vitamin	GO:0033273	131	0.015
fatty acid oxidation	GO:0019395	29	0.015
smooth muscle cell proliferation	GO:0048659	77	0.015
icosanoid biosynthetic process	GO:0046456	18	0.015
nitrogen compound transport	GO:0071705	229	0.015
lauric acid metabolic process	GO:0048252	4	0.015
response to glucose	GO:0009749	136	0.015
retinoid metabolic process	GO:0001523	24	0.015
programmed cell death	GO:0012501	392	0.015
response to starvation	GO:0042594	59	0.015
immune response	GO:0006955	104	0.015
regulation of anatomical structure size	GO:0090066	135	0.014
cellular response to ketone	GO:1901655	51	0.014
response to other organism	GO:0051707	220	0.014
choline transport	GO:0015871	4	0.014
regulation of cellular amine metabolic process	GO:0033238	8	0.014
nucleotide biosynthetic process	GO:0009165	98	0.014
single organism carbohydrate metabolic process	GO:0044723	118	0.014
organophosphate biosynthetic process	GO:0090407	143	0.014
ras protein signal transduction	GO:0007265	29	0.014
cellular response to peptide	GO:1901653	133	0.014
multicellular organism growth	GO:0035264	1	0.014
lipid transport	GO:0006869	61	0.014
regulation of phosphorylation	GO:0042325	248	0.014
response to mechanical stimulus	GO:0009612	134	0.014
small gtpase mediated signal transduction	GO:0007264	36	0.014
reproductive structure development	GO:0048608	128	0.014
regulation of protein modification process	GO:0031399	194	0.014
cellular response to cytokine stimulus	GO:0071345	127	0.014
regeneration	GO:0031099	163	0.014
cellular response to corticosteroid stimulus	GO:0071384	69	0.014
response to molecule of bacterial origin	GO:0002237	194	0.014
immune system process	GO:0002376	204	0.014
purine nucleoside metabolic process	GO:0042278	169	0.014
organ regeneration	GO:0031100	101	0.013
regulation of phosphorus metabolic process	GO:0051174	349	0.013
female pregnancy	GO:0007565	122	0.013
regulation of response to stress	GO:0080134	126	0.013
response to insulin	GO:0032868	133	0.013	Rat
epithelium development	GO:0060429	96	0.013
monovalent inorganic cation transport	GO:0015672	172	0.013
forebrain development	GO:0030900	98	0.013
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.013
cellular nitrogen compound catabolic process	GO:0044270	163	0.013
positive regulation of molecular function	GO:0044093	230	0.013
regulation of body fluid levels	GO:0050878	90	0.013
cellular response to molecule of bacterial origin	GO:0071219	56	0.013
regulation of smooth muscle cell proliferation	GO:0048660	75	0.013
carboxylic acid catabolic process	GO:0046395	49	0.013
positive regulation of cell proliferation	GO:0008284	249	0.013
icosanoid metabolic process	GO:0006690	38	0.013
sexual reproduction	GO:0019953	148	0.013
cellular component morphogenesis	GO:0032989	155	0.013
positive regulation of neurogenesis	GO:0050769	165	0.013
positive regulation of gene expression	GO:0010628	244	0.013
organonitrogen compound biosynthetic process	GO:1901566	167	0.013	Rat
calcium ion homeostasis	GO:0055074	162	0.013
sorbitol metabolic process	GO:0006060	1	0.013
response to lipopolysaccharide	GO:0032496	191	0.013
negative regulation of signaling	GO:0023057	157	0.013
response to growth factor	GO:0070848	189	0.013
behavior	GO:0007610	205	0.012
cardiac chamber development	GO:0003205	1	0.012
regulation of multicellular organismal development	GO:2000026	376	0.012
regulation of purine nucleotide metabolic process	GO:1900542	115	0.012
negative regulation of macromolecule metabolic process	GO:0010605	260	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
response to hypoxia	GO:0001666	231	0.012
response to cytokine	GO:0034097	215	0.012
cell cycle	GO:0007049	101	0.012
regulation of response to wounding	GO:1903034	69	0.012
reproductive system development	GO:0061458	128	0.012
nucleoside phosphate biosynthetic process	GO:1901293	102	0.012
coenzyme metabolic process	GO:0006732	86	0.012
transcription dna templated	GO:0006351	377	0.012
positive regulation of rna metabolic process	GO:0051254	203	0.012
positive regulation of smooth muscle cell proliferation	GO:0048661	51	0.012
regulation of system process	GO:0044057	208	0.012
muscle cell proliferation	GO:0033002	84	0.012
anion transmembrane transport	GO:0098656	77	0.012
negative regulation of cell communication	GO:0010648	158	0.012
regulation of nucleotide metabolic process	GO:0006140	117	0.012
cellular response to oxidative stress	GO:0034599	76	0.012
regulation of secretion	GO:0051046	224	0.012
positive regulation of response to stimulus	GO:0048584	285	0.012
glial cell differentiation	GO:0010001	65	0.012
regulation of ion transmembrane transport	GO:0034765	121	0.012
protein oligomerization	GO:0051259	191	0.011
peptidyl amino acid modification	GO:0018193	126	0.011
carbohydrate metabolic process	GO:0005975	130	0.011
aromatic compound catabolic process	GO:0019439	168	0.011
dna metabolic process	GO:0006259	96	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.011
response to purine containing compound	GO:0014074	126	0.011
response to testosterone	GO:0033574	55	0.011	Rat
regulation of response to external stimulus	GO:0032101	106	0.011
sex differentiation	GO:0007548	113	0.011
alditol metabolic process	GO:0019400	4	0.011
c21 steroid hormone metabolic process	GO:0008207	14	0.011
positive regulation of cellular biosynthetic process	GO:0031328	295	0.011
chemosensory behavior	GO:0007635	2	0.011
gamete generation	GO:0007276	124	0.011
amide transport	GO:0042886	105	0.011
positive regulation of protein metabolic process	GO:0051247	178	0.011
intestinal absorption	GO:0050892	3	0.011
urogenital system development	GO:0001655	78	0.011
negative regulation of cell death	GO:0060548	229	0.011
cellular response to lipopolysaccharide	GO:0071222	55	0.011
proteolysis	GO:0006508	175	0.011
cytoplasmic transport	GO:0016482	115	0.011
sensory perception	GO:0007600	101	0.011
regulation of protein phosphorylation	GO:0001932	183	0.011
hormone transport	GO:0009914	121	0.011
regulation of neuron differentiation	GO:0045664	208	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.011
reactive nitrogen species metabolic process	GO:2001057	1	0.011
positive regulation of phosphorylation	GO:0042327	177	0.010
positive regulation of rna biosynthetic process	GO:1902680	197	0.010
vascular process in circulatory system	GO:0003018	96	0.010
positive regulation of catabolic process	GO:0009896	78	0.010
single organism intracellular transport	GO:1902582	166	0.010
organic acid catabolic process	GO:0016054	49	0.010
regulation of cellular catabolic process	GO:0031329	101	0.010
purine ribonucleoside metabolic process	GO:0046128	168	0.010
embryonic pattern specification	GO:0009880	1	0.010
positive regulation of programmed cell death	GO:0043068	157	0.010
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.010
regulation of cell differentiation	GO:0045595	320	0.010
positive regulation of nucleotide metabolic process	GO:0045981	91	0.010
salivary gland development	GO:0007431	3	0.010
progesterone metabolic process	GO:0042448	8	0.010
apoptotic process	GO:0006915	381	0.010
regulation of neurogenesis	GO:0050767	247	0.010
neural crest cell development	GO:0014032	2	0.010

Cyp2j4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.019
disease of anatomical entity	DOID:7	0.017
nervous system disease	DOID:863	0.017
inherited metabolic disorder	DOID:655	0.012
central nervous system disease	DOID:331	0.010

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