Rattus norvegicus

38 known processes

Smpd2

sphingomyelin phosphodiesterase 2, neutral membrane

(Aliases: nSMase)

Smpd2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.089
positive regulation of nucleobase containing compound metabolic processGO:00459353190.070
regulation of rna biosynthetic processGO:20011413810.065
catabolic processGO:00090563510.063
organophosphate metabolic processGO:00196373700.063
organic substance catabolic processGO:19015753160.062
regulation of molecular functionGO:00650093980.062
organelle organizationGO:00069962660.062
purine containing compound metabolic processGO:00725212530.060
intracellular signal transductionGO:00355563140.059
single organism biosynthetic processGO:00447113420.058
apoptotic processGO:00069153810.055
regulation of phosphate metabolic processGO:00192203490.053
nucleic acid templated transcriptionGO:00976593790.052
positive regulation of cellular biosynthetic processGO:00313282950.052
regulation of phosphorus metabolic processGO:00511743490.051
regulation of rna metabolic processGO:00512523910.051
organic acid metabolic processGO:00060822920.051
regulation of transcription dna templatedGO:00063553740.050
neuron developmentGO:00486662860.050
positive regulation of nitrogen compound metabolic processGO:00511733340.049
programmed cell deathGO:00125013920.047
nucleoside phosphate metabolic processGO:00067532830.046
cellular response to stressGO:00335542690.046
anatomical structure morphogenesisGO:00096532980.046
ribonucleotide metabolic processGO:00092592310.046
rna biosynthetic processGO:00327743800.044
carbohydrate derivative metabolic processGO:19011353460.044
purine nucleotide metabolic processGO:00061632290.043
nucleotide metabolic processGO:00091172790.042
neuron differentiationGO:00301823680.042
positive regulation of cell communicationGO:00106472710.042
intracellular transportGO:00469071850.041
purine ribonucleoside metabolic processGO:00461281680.041
positive regulation of molecular functionGO:00440932300.040
nucleoside metabolic processGO:00091161790.040
cellular response to oxygen containing compoundGO:19017013860.040
positive regulation of transportGO:00510502450.039
nucleobase containing small molecule metabolic processGO:00550863160.039
cation transportGO:00068123820.039
protein phosphorylationGO:00064683450.039
single organism organelle organizationGO:19025891800.039
organic cyclic compound catabolic processGO:19013611750.038
positive regulation of gene expressionGO:00106282440.037
cellular amino acid metabolic processGO:00065201070.037
glycosyl compound metabolic processGO:19016571820.037
regulation of protein modification processGO:00313991940.036
aromatic compound catabolic processGO:00194391680.036
regulation of cellular protein metabolic processGO:00322682670.036
transmembrane transportGO:00550854120.036
positive regulation of biosynthetic processGO:00098913190.036
reproductive processGO:00224143720.036
purine ribonucleotide metabolic processGO:00091502270.036
positive regulation of catalytic activityGO:00430851840.036
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
positive regulation of signalingGO:00230562700.035
regulation of catalytic activityGO:00507903040.035
ribonucleotide catabolic processGO:00092611360.035
positive regulation of macromolecule biosynthetic processGO:00105572470.035
regulation of protein metabolic processGO:00512462890.034
transcription dna templatedGO:00063513770.034
regulation of cellular amino acid metabolic processGO:000652120.034
regulation of nucleic acid templated transcriptionGO:19035063800.034
chemical homeostasisGO:00488782920.034
regulation of phosphorylationGO:00423252480.034
cellular ketone metabolic processGO:0042180510.033
heterocycle catabolic processGO:00467001670.033
positive regulation of response to stimulusGO:00485842850.033
single organism catabolic processGO:00447122830.033
cellular catabolic processGO:00442482950.033
ribonucleoside triphosphate metabolic processGO:00091991410.033
neuron projection developmentGO:00311752730.033
regulation of cell proliferationGO:00421273590.032
purine ribonucleotide catabolic processGO:00091541360.032
purine nucleoside metabolic processGO:00422781690.032
amine metabolic processGO:0009308380.032
cellular component biogenesisGO:00440853680.032
response to peptideGO:19016522920.032
negative regulation of nitrogen compound metabolic processGO:00511721610.031
actin filament based processGO:0030029860.031
organonitrogen compound catabolic processGO:19015651790.031
negative regulation of macromolecule metabolic processGO:00106052600.031
cell projection organizationGO:00300303020.031
regulation of cellular component organizationGO:00511283680.030
negative regulation of cellular metabolic processGO:00313242810.030
regulation of intracellular signal transductionGO:19025312180.030
homeostatic processGO:00425923310.029
regulation of apoptotic processGO:00429813350.029
cellular amine metabolic processGO:0044106380.029
cellular component movementGO:00069282480.029
regulation of cellular amine metabolic processGO:003323880.029
transcription from rna polymerase ii promoterGO:00063662520.029
regulation of cellular ketone metabolic processGO:0010565270.029
purine containing compound catabolic processGO:00725231380.028
ribose phosphate metabolic processGO:00196932350.028
purine ribonucleoside catabolic processGO:00461301240.028
cellular nitrogen compound catabolic processGO:00442701630.028
negative regulation of metabolic processGO:00098923310.028
purine nucleoside triphosphate metabolic processGO:00091441410.028
regulation of signal transductionGO:00099663180.027
ribonucleoside metabolic processGO:00091191740.027
nucleoside triphosphate metabolic processGO:00091411440.027
negative regulation of macromolecule biosynthetic processGO:00105581480.027
oxoacid metabolic processGO:00434362900.027
response to nutrient levelsGO:00316673700.027
positive regulation of cellular protein metabolic processGO:00322701670.027
regulation of multicellular organismal developmentGO:20000263760.027
response to extracellular stimulusGO:00099913800.026
macromolecular complex assemblyGO:00650032730.026
store operated calcium entryGO:000211520.026
regulation of kinase activityGO:00435491170.025
nucleoside phosphate catabolic processGO:19012921400.025
secretionGO:00469033070.025
macromolecular complex subunit organizationGO:00439333390.025
cellular component assemblyGO:00226073600.025
nucleobase containing compound catabolic processGO:00346551520.024
carbohydrate derivative catabolic processGO:19011361470.024
reproductionGO:00000032450.024
protein complex subunit organizationGO:00718223020.024
cellular response to hormone stimulusGO:00328702470.024
positive regulation of phosphorus metabolic processGO:00105622620.024
negative regulation of nucleic acid templated transcriptionGO:19035071170.024
positive regulation of phosphate metabolic processGO:00459372620.024
metal ion transportGO:00300012890.023
protein localizationGO:00081041910.023
positive regulation of multicellular organismal processGO:00512403870.023
agingGO:00075682410.023
positive regulation of rna metabolic processGO:00512542030.023
single organism reproductive processGO:00447022970.023
central nervous system developmentGO:00074173110.023
regulation of cell differentiationGO:00455953200.023
response to ketoneGO:19016541820.023
multicellular organism reproductionGO:00325042330.023
response to biotic stimulusGO:00096072260.023
negative regulation of cellular biosynthetic processGO:00313271610.022
negative regulation of gene expressionGO:00106291990.022
negative regulation of molecular functionGO:00440921330.022
regulation of membrane potentialGO:00423911100.022
multicellular organismal reproductive processGO:00486092330.022
glycosyl compound catabolic processGO:19016581260.022
macromolecule localizationGO:00330362520.022
response to other organismGO:00517072200.022
ribonucleoside catabolic processGO:00424541260.021
ribonucleoside triphosphate catabolic processGO:00092031220.021
regulation of protein kinase activityGO:00458591050.021
positive regulation of cellular amine metabolic processGO:003324030.021
purine nucleotide catabolic processGO:00061951360.021
protein complex assemblyGO:00064612630.021
multi organism reproductive processGO:00447032620.021
regulation of transferase activityGO:00513381230.021
purine nucleoside catabolic processGO:00061521240.021
ion transmembrane transportGO:00342203650.021
regulation of programmed cell deathGO:00430673410.020
negative regulation of rna biosynthetic processGO:19026791180.020
positive regulation of transcription dna templatedGO:00458931970.020
purine ribonucleoside triphosphate metabolic processGO:00092051400.020
response to cytokineGO:00340972150.020
positive regulation of signal transductionGO:00099671750.020
cellular homeostasisGO:00197252520.020
response to inorganic substanceGO:00100353770.020
cytoskeleton organizationGO:00070101110.020
protein complex biogenesisGO:00702712630.020
carboxylic acid metabolic processGO:00197522890.020
single organism intracellular transportGO:19025821660.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
negative regulation of cell communicationGO:00106481580.019
cell cell signalingGO:00072673350.019
brain developmentGO:00074202470.019
defense responseGO:00069521940.019
organophosphate biosynthetic processGO:00904071430.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
nucleotide catabolic processGO:00091661390.019
nucleoside catabolic processGO:00091641260.019
organophosphate catabolic processGO:00464341480.019
developmental process involved in reproductionGO:00030061590.019
response to external biotic stimulusGO:00432072210.019
response to oxidative stressGO:00069791860.018
positive regulation of phosphorylationGO:00423271770.018
cell migrationGO:00164771970.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
regulation of cell developmentGO:00602842630.018
negative regulation of cell deathGO:00605482290.018
negative regulation of apoptotic processGO:00430661810.018
neurological system processGO:00508772190.018
positive regulation of cellular amino acid metabolic processGO:004576410.017
lipid metabolic processGO:00066292830.017
embryonic pattern specificationGO:000988010.017
cellular response to cytokine stimulusGO:00713451270.017
negative regulation of transcription dna templatedGO:00458921160.017
negative regulation of rna metabolic processGO:00512531230.017
chromosome segregationGO:000705920.017
response to nutrientGO:00075842480.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
regulation of cellular localizationGO:00603412630.017
negative regulation of protein metabolic processGO:00512481140.017
regulation of neurogenesisGO:00507672470.017
positive regulation of protein metabolic processGO:00512471780.017
establishment of protein localizationGO:00451841410.017
response to woundingGO:00096112540.017
tissue developmentGO:00098882520.017
gamete generationGO:00072761240.017
cell morphogenesisGO:00009021420.017
response to hypoxiaGO:00016662310.017
response to peptide hormoneGO:00434342780.017
response to purine containing compoundGO:00140741260.017
negative regulation of signalingGO:00230571570.016
purine nucleoside monophosphate metabolic processGO:0009126840.016
positive regulation of rna biosynthetic processGO:19026801970.016
locomotionGO:00400112370.016
response to decreased oxygen levelsGO:00362932370.016
regulation of protein phosphorylationGO:00019321830.016
small gtpase mediated signal transductionGO:0007264360.016
regulation of response to stressGO:00801341260.016
negative regulation of response to stimulusGO:00485851550.015
response to estrogenGO:00436272320.015
response to ethanolGO:00454711620.015
single organism carbohydrate metabolic processGO:00447231180.015
response to insulinGO:00328681330.015
single organism cellular localizationGO:19025801020.015
response to oxygen levelsGO:00704822650.015
nucleoside triphosphate catabolic processGO:00091431230.015
cellular component morphogenesisGO:00329891550.015
response to bacteriumGO:00096172000.015
positive regulation of protein modification processGO:00314011420.015
cellular chemical homeostasisGO:00550822470.015
cellular response to nitrogen compoundGO:19016992100.015
metal ion homeostasisGO:00550651860.015
positive regulation of catabolic processGO:0009896780.015
cell projection morphogenesisGO:00488581230.015
positive regulation of neurogenesisGO:00507691650.014
axis specificationGO:000979840.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
membrane organizationGO:0061024940.014
cellular response to endogenous stimulusGO:00714953770.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
regulation of catabolic processGO:00098941130.014
response to acid chemicalGO:00011012220.014
negative regulation of programmed cell deathGO:00430691830.014
carbohydrate metabolic processGO:00059751300.014
negative regulation of cellular protein metabolic processGO:00322691060.014
response to vitaminGO:00332731310.014
regulation of response to external stimulusGO:00321011060.014
cell cycleGO:00070491010.014
regulation of cell projection organizationGO:00313441750.014
positive regulation of cell proliferationGO:00082842490.014
regulation of system processGO:00440572080.014
positive regulation of cellular component organizationGO:00511302000.014
regulation of nucleotide metabolic processGO:00061401170.014
organonitrogen compound biosynthetic processGO:19015661670.014
response to organophosphorusGO:00466831020.014
response to growth factorGO:00708481890.014
positive regulation of developmental processGO:00510942830.014
positive regulation of hydrolase activityGO:0051345860.014
divalent inorganic cation homeostasisGO:00725071650.013
regulation of fat cell differentiationGO:004559830.013
positive regulation of protein phosphorylationGO:00019341350.013
proteolysisGO:00065081750.013
monovalent inorganic cation transportGO:00156721720.013
cellular response to growth factor stimulusGO:00713631620.013
secretion by cellGO:00329402480.013
regulation of hydrolase activityGO:00513361430.013
response to transition metal nanoparticleGO:19902671220.013
regulation of defense responseGO:0031347680.013
positive regulation of nucleoside metabolic processGO:0045979550.013
sexual reproductionGO:00199531480.013
regulation of neuron deathGO:19012141150.013
regulation of cellular component movementGO:00512701500.013
response to lipopolysaccharideGO:00324961910.013
single organism membrane organizationGO:0044802740.013
negative regulation of catalytic activityGO:00430861030.013
axon developmentGO:0061564960.013
ion homeostasisGO:00508012120.013
anterior posterior pattern specificationGO:000995210.013
regulation of ion transportGO:00432692450.012
heart morphogenesisGO:000300730.012
cellular macromolecule localizationGO:00707271220.012
action potentialGO:0001508540.012
cell motilityGO:00488702020.012
positive regulation of intracellular signal transductionGO:19025331380.012
regulation of anatomical structure sizeGO:00900661350.012
gastrulationGO:000736920.012
regulation of purine nucleotide metabolic processGO:19005421150.012
positive regulation of cell developmentGO:00107201760.012
regulation of nervous system developmentGO:00519602640.012
nucleoside monophosphate metabolic processGO:0009123930.012
localization of cellGO:00516742020.012
gland developmentGO:00487321550.012
cellular carbohydrate metabolic processGO:0044262720.012
cation homeostasisGO:00550801950.012
positive regulation of apoptotic processGO:00430651540.012
chemosensory behaviorGO:000763520.012
actin cytoskeleton organizationGO:0030036730.012
head developmentGO:00603222470.012
regulation of cell migrationGO:00303341280.012
vesicle mediated transportGO:00161921810.012
ribonucleoside monophosphate metabolic processGO:0009161880.012
cell adhesionGO:00071551100.012
oxidation reduction processGO:00551143040.012
response to carbohydrateGO:00097431830.012
positive regulation of secretion by cellGO:19035321280.012
cellular response to lipidGO:00713962010.012
positive regulation of cell deathGO:00109421840.012
response to metal ionGO:00100382530.011
immune effector processGO:0002252530.011
regulation of neuron projection developmentGO:00109751610.011
divalent inorganic cation transportGO:00725111340.011
nitrogen compound transportGO:00717052290.011
cellular response to external stimulusGO:00714961180.011
response to reactive oxygen speciesGO:00003021200.011
cell cycle checkpointGO:000007520.011
regulation of metal ion transportGO:00109591180.011
cytosolic calcium ion homeostasisGO:00514801400.011
carbohydrate derivative biosynthetic processGO:19011371240.011
dephosphorylationGO:0016311980.011
regulation of neuron differentiationGO:00456642080.011
regulation of immune system processGO:00026821230.011
immune system processGO:00023762040.011
g protein coupled receptor signaling pathwayGO:00071862420.011
intracellular protein transportGO:0006886790.011
ras protein signal transductionGO:0007265290.011
cellular protein localizationGO:00346131220.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
gtp metabolic processGO:0046039720.011
cellular response to organic cyclic compoundGO:00714072020.011
cell part morphogenesisGO:00329901230.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
negative regulation of innate immune responseGO:004582440.011
cellular metal ion homeostasisGO:00068751720.011
behaviorGO:00076102050.011
positive regulation of cellular catabolic processGO:0031331710.011
negative regulation of phosphate metabolic processGO:0045936800.011
muscle system processGO:00030121150.011
divalent metal ion transportGO:00708381320.011
calcium ion transportGO:00068161310.010
protein transportGO:00150311320.010
reactive oxygen species biosynthetic processGO:190340980.010
positive regulation of programmed cell deathGO:00430681570.010
response to hydrogen peroxideGO:0042542890.010
purine ribonucleoside monophosphate metabolic processGO:0009167840.010
positive regulation of neuron differentiationGO:00456661260.010
male gamete generationGO:0048232990.010
anion transportGO:00068201780.010
positive regulation of nervous system developmentGO:00519621780.010
cellular response to organonitrogen compoundGO:00714171970.010
lipid storageGO:001991510.010
defense response to gram negative bacteriumGO:005082930.010
negative regulation of multicellular organismal processGO:00512412030.010
muscle contractionGO:0006936880.010

Smpd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
sensory system diseaseDOID:005015500.016
musculoskeletal system diseaseDOID:1700.014
central nervous system diseaseDOID:33100.011