Rattus norvegicus

160 known processes

Pias2

protein inhibitor of activated STAT, 2

(Aliases: Miz1)

Pias2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.156
regulation of programmed cell deathGO:00430673410.136
positive regulation of cellular protein metabolic processGO:00322701670.130
cellular catabolic processGO:00442482950.121
regulation of cellular protein metabolic processGO:00322682670.119
Yeast
transcription from rna polymerase ii promoterGO:00063662520.111
transcription dna templatedGO:00063513770.110
regulation of phosphorus metabolic processGO:00511743490.107
regulation of protein metabolic processGO:00512462890.104
Yeast
nucleic acid templated transcriptionGO:00976593790.103
programmed cell deathGO:00125013920.101
neuron differentiationGO:00301823680.101
regulation of molecular functionGO:00650093980.101
regulation of phosphate metabolic processGO:00192203490.097
regulation of nucleic acid templated transcriptionGO:19035063800.096
chromosome segregationGO:000705920.095
Yeast
protein phosphorylationGO:00064683450.092
regulation of signal transductionGO:00099663180.091
regulation of rna biosynthetic processGO:20011413810.084
positive regulation of cellular component organizationGO:00511302000.082
negative regulation of metabolic processGO:00098923310.081
Yeast
positive regulation of phosphorus metabolic processGO:00105622620.074
reproductive processGO:00224143720.073
negative regulation of cellular metabolic processGO:00313242810.073
Yeast
neuron projection developmentGO:00311752730.072
cellular response to endogenous stimulusGO:00714953770.071
organelle organizationGO:00069962660.070
regulation of catalytic activityGO:00507903040.069
regulation of cellular component organizationGO:00511283680.069
positive regulation of cell deathGO:00109421840.066
cellular response to peptideGO:19016531330.065
regulation of transcription dna templatedGO:00063553740.065
regulation of anatomical structure morphogenesisGO:00226031410.065
regulation of rna metabolic processGO:00512523910.064
negative regulation of programmed cell deathGO:00430691830.062
cellular response to stressGO:00335542690.061
positive regulation of apoptotic processGO:00430651540.061
positive regulation of biosynthetic processGO:00098913190.060
multi organism reproductive processGO:00447032620.059
regulation of apoptotic processGO:00429813350.059
organic substance catabolic processGO:19015753160.058
mesoderm developmentGO:000749820.058
positive regulation of programmed cell deathGO:00430681570.058
negative regulation of cell deathGO:00605482290.058
single organism reproductive processGO:00447022970.057
positive regulation of nitrogen compound metabolic processGO:00511733340.055
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.055
cellular component biogenesisGO:00440853680.055
regulation of protein modification processGO:00313991940.054
Yeast
positive regulation of protein modification processGO:00314011420.053
positive regulation of nucleobase containing compound metabolic processGO:00459353190.052
regulation of cell developmentGO:00602842630.052
response to oxygen levelsGO:00704822650.052
response to peptideGO:19016522920.052
negative regulation of macromolecule metabolic processGO:00106052600.051
Yeast
rna metabolic processGO:00160704060.051
catabolic processGO:00090563510.050
smad protein complex assemblyGO:000718310.049
somatic stem cell divisionGO:004810320.049
positive regulation of response to stimulusGO:00485842850.049
positive regulation of rna biosynthetic processGO:19026801970.048
regulation of transcription from rna polymerase ii promoterGO:00063572340.048
positive regulation of multicellular organismal processGO:00512403870.047
cell morphogenesis involved in differentiationGO:00009041190.047
response to peptide hormoneGO:00434342780.047
multicellular organismal reproductive processGO:00486092330.047
regulation of nervous system developmentGO:00519602640.046
positive regulation of protein metabolic processGO:00512471780.046
cellular response to organonitrogen compoundGO:00714171970.046
neuron developmentGO:00486662860.046
asymmetric stem cell divisionGO:009872220.045
regulation of cell differentiationGO:00455953200.045
dephosphorylationGO:0016311980.045
ribonucleoside metabolic processGO:00091191740.045
regulation of protein phosphorylationGO:00019321830.044
cellular response to nitrogen compoundGO:19016992100.044
regulation of neurogenesisGO:00507672470.044
regulation of catabolic processGO:00098941130.044
regulation of hydrolase activityGO:00513361430.043
regulation of neuron projection developmentGO:00109751610.043
protein complex assemblyGO:00064612630.043
positive regulation of molecular functionGO:00440932300.043
regulation of multicellular organismal developmentGO:20000263760.043
cellular protein localizationGO:00346131220.043
proteolysisGO:00065081750.042
positive regulation of transcription dna templatedGO:00458931970.042
positive regulation of rna metabolic processGO:00512542030.042
macromolecule localizationGO:00330362520.042
cation transportGO:00068123820.042
Rat
positive regulation of cellular biosynthetic processGO:00313282950.041
positive regulation of phosphate metabolic processGO:00459372620.041
organophosphate metabolic processGO:00196373700.041
cellular component movementGO:00069282480.040
macromolecular complex subunit organizationGO:00439333390.039
multicellular organism reproductionGO:00325042330.039
cellular component morphogenesisGO:00329891550.039
intracellular transportGO:00469071850.038
negative regulation of biosynthetic processGO:00098901680.038
neuron projection morphogenesisGO:00488121220.038
response to estrogenGO:00436272320.038
macromolecular complex assemblyGO:00650032730.038
embryonic pattern specificationGO:000988010.037
mapk cascadeGO:00001651400.037
single organism intracellular transportGO:19025821660.037
protein transportGO:00150311320.037
protein localizationGO:00081041910.037
response to growth factorGO:00708481890.037
cellular amino acid metabolic processGO:00065201070.037
carbohydrate derivative metabolic processGO:19011353460.037
apoptotic processGO:00069153810.036
single organism organelle organizationGO:19025891800.036
negative regulation of rna biosynthetic processGO:19026791180.036
positive regulation of macromolecule biosynthetic processGO:00105572470.036
cellular response to growth factor stimulusGO:00713631620.036
establishment of protein localizationGO:00451841410.036
cellular response to oxygen containing compoundGO:19017013860.035
cell morphogenesisGO:00009021420.035
regulation of transforming growth factor beta3 productionGO:003291020.035
positive regulation of cell projection organizationGO:00313461110.035
signal transduction by phosphorylationGO:00230141440.035
nucleobase containing small molecule metabolic processGO:00550863160.035
mitotic cell cycleGO:0000278490.035
cytoskeleton organizationGO:00070101110.035
negative regulation of cell communicationGO:00106481580.035
cell migrationGO:00164771970.035
rna biosynthetic processGO:00327743800.034
anatomical structure morphogenesisGO:00096532980.034
vesicle mediated transportGO:00161921810.034
cellular component assemblyGO:00226073600.034
negative regulation of gene expressionGO:00106291990.034
Yeast
negative regulation of nitrogen compound metabolic processGO:00511721610.034
regulation of phosphorylationGO:00423252480.033
response to cytokineGO:00340972150.033
response to hypoxiaGO:00016662310.033
sexual reproductionGO:00199531480.033
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.033
behaviorGO:00076102050.033
negative regulation of signalingGO:00230571570.032
negative regulation of nucleic acid templated transcriptionGO:19035071170.032
developmental process involved in reproductionGO:00030061590.032
cell projection organizationGO:00300303020.032
inorganic ion transmembrane transportGO:00986602290.032
Rat
purine containing compound metabolic processGO:00725212530.031
response to carbohydrateGO:00097431830.031
regulation of cellular catabolic processGO:00313291010.031
response to insulinGO:00328681330.031
protein complex biogenesisGO:00702712630.031
cellular response to peptide hormone stimulusGO:00713751200.031
gamete generationGO:00072761240.031
cellular response to insulin stimulusGO:0032869810.031
negative regulation of response to stimulusGO:00485851550.030
positive regulation of gene expressionGO:00106282440.030
negative regulation of rna metabolic processGO:00512531230.030
ribonucleotide metabolic processGO:00092592310.030
circulatory system developmentGO:00723591340.030
negative regulation of multicellular organismal processGO:00512412030.030
bmp signaling pathwayGO:003050940.030
cellular ketone metabolic processGO:0042180510.030
actin filament based processGO:0030029860.030
purine ribonucleotide metabolic processGO:00091502270.030
response to inorganic substanceGO:00100353770.029
neurological system processGO:00508772190.029
regulation of cell projection organizationGO:00313441750.029
cell motilityGO:00488702020.029
positive regulation of cell differentiationGO:00455972170.029
biological adhesionGO:00226101100.029
cellular response to hormone stimulusGO:00328702470.029
chemotaxisGO:0006935660.029
cardiovascular system developmentGO:00723581340.029
negative regulation of transcription dna templatedGO:00458921160.028
nucleoside phosphate metabolic processGO:00067532830.028
reproductionGO:00000032450.028
positive regulation of phosphorylationGO:00423271770.028
small gtpase mediated signal transductionGO:0007264360.028
cell type specific apoptotic processGO:00972851340.028
positive regulation of developmental processGO:00510942830.028
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.028
metal ion transportGO:00300012890.028
Rat
carbohydrate derivative catabolic processGO:19011361470.028
purine nucleotide catabolic processGO:00061951360.028
negative regulation of nucleobase containing compound metabolic processGO:00459341530.028
response to nutrient levelsGO:00316673700.028
locomotionGO:00400112370.028
g protein coupled receptor signaling pathwayGO:00071862420.027
renal system developmentGO:0072001670.027
positive regulation of catalytic activityGO:00430851840.027
regulation of cell cycleGO:0051726730.027
regulation of intracellular signal transductionGO:19025312180.027
organonitrogen compound catabolic processGO:19015651790.027
cell cycleGO:00070491010.027
positive regulation of signalingGO:00230562700.027
cell part morphogenesisGO:00329901230.027
response to decreased oxygen levelsGO:00362932370.027
organic acid metabolic processGO:00060822920.026
single organism catabolic processGO:00447122830.026
actin cytoskeleton organizationGO:0030036730.026
response to monosaccharideGO:00342841590.026
protein complex subunit organizationGO:00718223020.025
response to ketoneGO:19016541820.025
cation transmembrane transportGO:00986552630.025
Rat
negative regulation of macromolecule biosynthetic processGO:00105581480.025
tissue developmentGO:00098882520.025
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.025
regulation of cellular localizationGO:00603412630.025
spindle organizationGO:000705120.025
protein refoldingGO:004202630.025
regulation of cellular amino acid metabolic processGO:000652120.025
negative regulation of cellular biosynthetic processGO:00313271610.024
regulation of cellular response to stressGO:0080135490.024
axis specificationGO:000979840.024
homeostatic processGO:00425923310.024
protein localization to organelleGO:0033365570.024
positive regulation of cell communicationGO:00106472710.024
brain developmentGO:00074202470.024
oxoacid metabolic processGO:00434362900.024
regulation of transferase activityGO:00513381230.024
positive regulation of hydrolase activityGO:0051345860.024
transmembrane transportGO:00550854120.024
Rat
ribose phosphate metabolic processGO:00196932350.024
embryonic axis specificationGO:000057810.024
cellular amine metabolic processGO:0044106380.024
cellular chemical homeostasisGO:00550822470.024
amine metabolic processGO:0009308380.024
response to nutrientGO:00075842480.024
cytoplasmic transportGO:00164821150.023
cellular macromolecule localizationGO:00707271220.023
regulation of cellular amine metabolic processGO:003323880.023
regulation of cellular ketone metabolic processGO:0010565270.023
carboxylic acid metabolic processGO:00197522890.023
negative regulation of molecular functionGO:00440921330.023
ion transmembrane transportGO:00342203650.023
Rat
calcium ion transportGO:00068161310.023
regulation of neuron differentiationGO:00456642080.023
peptidyl amino acid modificationGO:00181931260.023
cell adhesionGO:00071551100.023
positive regulation of cellular amine metabolic processGO:003324030.022
heterocycle catabolic processGO:00467001670.022
negative regulation of apoptotic processGO:00430661810.022
regulation of protein phosphatase type 2a activityGO:003404720.022
response to glucoseGO:00097491360.022
response to ethanolGO:00454711620.022
ras protein signal transductionGO:0007265290.022
regulation of locomotionGO:00400121480.022
cell projection morphogenesisGO:00488581230.022
positive regulation of signal transductionGO:00099671750.022
regulation of cell morphogenesis involved in differentiationGO:0010769720.022
positive regulation of biomineral tissue developmentGO:007016940.021
inorganic cation transmembrane transportGO:00986622020.021
Rat
cellular homeostasisGO:00197252520.021
cellular response to organic cyclic compoundGO:00714072020.021
negative regulation of cell proliferationGO:00082851190.021
cell morphogenesis involved in neuron differentiationGO:00486671060.021
regulation of cell migrationGO:00303341280.021
chemical homeostasisGO:00488782920.020
regulation of cell proliferationGO:00421273590.020
purine ribonucleotide catabolic processGO:00091541360.020
cardiac ventricle developmentGO:000323110.020
purine ribonucleoside metabolic processGO:00461281680.020
urogenital system developmentGO:0001655780.020
positive regulation of cell developmentGO:00107201760.020
regulation of bmp signaling pathwayGO:003051020.020
response to other organismGO:00517072200.020
organophosphate catabolic processGO:00464341480.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.019
cellular nitrogen compound catabolic processGO:00442701630.019
blood circulationGO:00080151830.019
neuronal stem cell divisionGO:003644510.019
response to woundingGO:00096112540.019
metal ion homeostasisGO:00550651860.019
cellular response to cytokine stimulusGO:00713451270.019
glycosyl compound metabolic processGO:19016571820.019
purine ribonucleoside catabolic processGO:00461301240.019
localization of cellGO:00516742020.019
ribonucleoside catabolic processGO:00424541260.019
gastrulationGO:000736920.018
response to extracellular stimulusGO:00099913800.018
transforming growth factor beta3 productionGO:003290720.018
regulation of neuron deathGO:19012141150.018
regulation of cell morphogenesisGO:0022604770.018
regulation of response to stressGO:00801341260.018
protein dephosphorylationGO:0006470380.018
response to radiationGO:00093141370.018
positive regulation of transferase activityGO:0051347810.018
nucleoside phosphate catabolic processGO:19012921400.018
response to mechanical stimulusGO:00096121340.018
response to hexoseGO:00097461440.018
endocytosisGO:0006897840.017
response to toxic substanceGO:00096361330.017
wound healingGO:00420601220.017
positive regulation of neurogenesisGO:00507691650.017
regulation of kinase activityGO:00435491170.017
cell cycle checkpointGO:000007520.017
p38mapk cascadeGO:003806610.017
nucleobase containing compound catabolic processGO:00346551520.017
centrosome organizationGO:005129710.017
nucleoside metabolic processGO:00091161790.017
organic cyclic compound catabolic processGO:19013611750.017
purine containing compound biosynthetic processGO:0072522850.017
response to biotic stimulusGO:00096072260.017
nucleoside triphosphate catabolic processGO:00091431230.017
negative regulation of mitotic cell cycle phase transitionGO:190199130.017
heart developmentGO:0007507720.016
nucleotide catabolic processGO:00091661390.016
macromolecule catabolic processGO:0009057580.016
defense responseGO:00069521940.016
central nervous system developmentGO:00074173110.016
multicellular organism growthGO:003526410.016
nucleoside catabolic processGO:00091641260.016
actin filament organizationGO:0007015420.016
negative regulation of cellular component organizationGO:0051129830.016
dendrite developmentGO:0016358720.016
response to external biotic stimulusGO:00432072210.016
purine nucleotide metabolic processGO:00061632290.016
negative regulation of signal transductionGO:0009968830.016
taxisGO:0042330670.016
agingGO:00075682410.016
regulation of response to external stimulusGO:00321011060.016
anterior posterior pattern specificationGO:000995210.016
negative regulation of protein metabolic processGO:00512481140.016
Yeast
posttranscriptional regulation of gene expressionGO:0010608370.016
developmental growthGO:00485891000.015
guanosine containing compound metabolic processGO:1901068740.015
rhythmic processGO:00485111560.015
positive regulation of cell proliferationGO:00082842490.015
positive regulation of protein serine threonine kinase activityGO:0071902520.015
growthGO:00400071650.015
regulation of growthGO:00400081050.015
synaptic growth at neuromuscular junctionGO:005112410.015
regulation of proteolysisGO:0030162660.015
purine nucleoside catabolic processGO:00061521240.015
negative regulation of transportGO:00510511360.015
neuron apoptotic processGO:0051402880.015
cardiac chamber developmentGO:000320510.015
camp metabolic processGO:0046058630.015
response to metal ionGO:00100382530.015
muscle system processGO:00030121150.015
single organism cellular localizationGO:19025801020.015
regulation of system processGO:00440572080.015
stem cell divisionGO:001714540.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
positive regulation of bone mineralizationGO:003050140.015
aromatic compound catabolic processGO:00194391680.015
negative regulation of cell cycle phase transitionGO:190198840.015
axon developmentGO:0061564960.015
response to corticosteroidGO:00319602350.015
dna metabolic processGO:0006259960.015
protein modification by small protein conjugationGO:0032446310.015
Yeast
positive regulation of mapk cascadeGO:0043410920.015
transforming growth factor beta receptor signaling pathwayGO:0007179180.014
response to bacteriumGO:00096172000.014
secretion by cellGO:00329402480.014
regulation of stem cell differentiationGO:200073620.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
regulation of stress activated protein kinase signaling cascadeGO:0070302230.014
regulation of cellular component biogenesisGO:0044087860.014
ribonucleotide catabolic processGO:00092611360.014
protein oligomerizationGO:00512591910.014
response to transforming growth factor betaGO:0071559460.014
circulatory system processGO:00030131830.014
purine nucleoside triphosphate catabolic processGO:00091461220.014
cognitionGO:0050890920.014
regulation of purine nucleotide metabolic processGO:19005421150.014
cellular response to transforming growth factor beta stimulusGO:0071560410.014
kidney developmentGO:0001822670.014
cellular response to external stimulusGO:00714961180.014
negative regulation of phosphorus metabolic processGO:0010563800.014
regulation of cellular component movementGO:00512701500.014
cellular response to steroid hormone stimulusGO:0071383930.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
regulation of protein serine threonine kinase activityGO:0071900640.013
nucleoside triphosphate metabolic processGO:00091411440.013
glycosyl compound catabolic processGO:19016581260.013
regulation of nucleotide metabolic processGO:00061401170.013
response to lipopolysaccharideGO:00324961910.013
regulation of mapk cascadeGO:00434081160.013
regulation of ion transportGO:00432692450.013
purine containing compound catabolic processGO:00725231380.013
muscle tissue developmentGO:0060537580.013
positive regulation of protein kinase activityGO:0045860730.013
negative regulation of phosphate metabolic processGO:0045936800.013
positive regulation of neuron differentiationGO:00456661260.013
cellular response to lipidGO:00713962010.013
organic hydroxy compound metabolic processGO:19016151150.013
alpha amino acid metabolic processGO:1901605710.013
synapse organizationGO:0050808460.013
cell cycle processGO:0022402570.013
regulation of protein kinase activityGO:00458591050.013
cell fate determinationGO:000170920.013
positive regulation of transforming growth factor beta3 productionGO:003291620.013
regulation of activin receptor signaling pathwayGO:003292510.012
protein autophosphorylationGO:0046777660.012
positive regulation of catabolic processGO:0009896780.012
positive regulation of neuron projection developmentGO:0010976990.012
organophosphate biosynthetic processGO:00904071430.012
positive regulation of cellular component movementGO:00512721020.012
secretionGO:00469033070.012
negative regulation of nervous system developmentGO:0051961790.012
response to estradiolGO:00323551640.012
positive regulation of transportGO:00510502450.012
transmission of nerve impulseGO:0019226420.012
positive regulation of jnk cascadeGO:0046330130.012
purine nucleoside metabolic processGO:00422781690.012
protein catabolic processGO:0030163300.012
regulation of dendrite morphogenesisGO:0048814330.012
lipid metabolic processGO:00066292830.012
head developmentGO:00603222470.012
regulation of anatomical structure sizeGO:00900661350.012
positive regulation of locomotionGO:00400171020.012
positive regulation of protein phosphorylationGO:00019341350.012
protein targetingGO:0006605610.012
single organism behaviorGO:00447081300.012
cellular macromolecular complex assemblyGO:0034622580.012
regulation of dna metabolic processGO:0051052600.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
response to molecule of bacterial originGO:00022371940.012
guanosine containing compound catabolic processGO:1901069710.012
regulation of cytokine productionGO:0001817560.012
eye morphogenesisGO:004859240.012
common partner smad protein phosphorylationGO:000718210.012
response to alkaloidGO:00432791320.012
signal releaseGO:00230611450.012
divalent metal ion transportGO:00708381320.012
positive regulation of cellular catabolic processGO:0031331710.012
neuron deathGO:00709971270.012
protein importGO:0017038370.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.012
positive regulation of cell motilityGO:2000147970.011
divalent inorganic cation transportGO:00725111340.011
regulation of secretion by cellGO:19035302080.011
muscle structure developmentGO:0061061870.011
positive regulation of cellular component biogenesisGO:0044089550.011
gtp catabolic processGO:0006184710.011
protein modification by small protein conjugation or removalGO:0070647350.011
Yeast
rho protein signal transductionGO:0007266110.011
cellular process involved in reproduction in multicellular organismGO:0022412350.011
single organism biosynthetic processGO:00447113420.011
mitotic cell cycle processGO:1903047350.011
nitrogen compound transportGO:00717052290.011
response to transition metal nanoparticleGO:19902671220.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424340.011
cellular cation homeostasisGO:00300031800.011
atp catabolic processGO:0006200540.011
spermatogenesisGO:0007283990.011
apoptotic signaling pathwayGO:0097190270.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296830.011
nucleotide biosynthetic processGO:0009165980.011
synaptic transmissionGO:00072682350.011
memoryGO:0007613540.011
response to glucocorticoidGO:00513842230.011
nucleotide metabolic processGO:00091172790.011
muscle contractionGO:0006936880.011
learning or memoryGO:0007611900.011
defense response to gram negative bacteriumGO:005082930.011
positive regulation of intracellular signal transductionGO:19025331380.011
cell cycle phase transitionGO:0044770210.011
regulation of peptidase activityGO:0052547550.011
stress activated mapk cascadeGO:0051403350.011
positive regulation of cytokine productionGO:0001819420.011
male gamete generationGO:0048232990.010
positive regulation of nervous system developmentGO:00519621780.010
axonogenesisGO:0007409710.010
positive regulation of response to external stimulusGO:0032103510.010
anion transportGO:00068201780.010
nucleoside monophosphate metabolic processGO:0009123930.010
microtubule organizing center organizationGO:003102310.010
cellular calcium ion homeostasisGO:00068741600.010
heart processGO:0003015570.010
activation of cysteine type endopeptidase activityGO:009720240.010
cellular response to alcoholGO:0097306870.010
dna integrity checkpointGO:003157020.010
regulation of secretionGO:00510462240.010
response to acid chemicalGO:00011012220.010
negative regulation of catalytic activityGO:00430861030.010
positive regulation of kinase activityGO:0033674770.010

Pias2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
disease of metabolismDOID:001466700.019
sensory system diseaseDOID:005015500.015
inherited metabolic disorderDOID:65500.015
musculoskeletal system diseaseDOID:1700.011
central nervous system diseaseDOID:33100.011