IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Trim17

tripartite motif-containing 17

(Aliases: Rnf16)

RGD: 69290
Ensembl: ENSRNOG00000022983
Entrez: 64702
UniProtKB: Q9WV59

Process Predictions
Disease Predictions

Trim17 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
regulation of nucleic acid templated transcription	GO:1903506	380	0.160
regulation of phosphorus metabolic process	GO:0051174	349	0.148
anatomical structure morphogenesis	GO:0009653	298	0.142
brain development	GO:0007420	247	0.140
positive regulation of phosphorus metabolic process	GO:0010562	262	0.135
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.132
regulation of cellular localization	GO:0060341	263	0.118
regulation of hormone secretion	GO:0046883	106	0.103
organophosphate metabolic process	GO:0019637	370	0.101
tissue development	GO:0009888	252	0.096
neuron differentiation	GO:0030182	368	0.095
purine nucleotide biosynthetic process	GO:0006164	83	0.092
macromolecular complex subunit organization	GO:0043933	339	0.091
organic substance catabolic process	GO:1901575	316	0.090
positive regulation of biosynthetic process	GO:0009891	319	0.087
head development	GO:0060322	247	0.083
cellular calcium ion homeostasis	GO:0006874	160	0.081
macromolecular complex assembly	GO:0065003	273	0.079
single organism biosynthetic process	GO:0044711	342	0.077
negative regulation of transport	GO:0051051	136	0.076
regulation of apoptotic process	GO:0042981	335	0.074
negative regulation of cellular metabolic process	GO:0031324	281	0.074
negative regulation of cellular biosynthetic process	GO:0031327	161	0.073
negative regulation of apoptotic process	GO:0043066	181	0.069
signal release	GO:0023061	145	0.068
intracellular signal transduction	GO:0035556	314	0.067
negative regulation of programmed cell death	GO:0043069	183	0.066
negative regulation of gene expression	GO:0010629	199	0.066
positive regulation of molecular function	GO:0044093	230	0.066
regulation of intracellular signal transduction	GO:1902531	218	0.064
g protein coupled receptor signaling pathway	GO:0007186	242	0.064
cation homeostasis	GO:0055080	195	0.062
negative regulation of metabolic process	GO:0009892	331	0.062
neuron projection development	GO:0031175	273	0.061
protein complex assembly	GO:0006461	263	0.060
regulation of secretion	GO:0051046	224	0.059
regulation of programmed cell death	GO:0043067	341	0.059
cellular component morphogenesis	GO:0032989	155	0.056
regulation of transcription dna templated	GO:0006355	374	0.056
programmed cell death	GO:0012501	392	0.052
regulation of rna biosynthetic process	GO:2001141	381	0.052
hormone transport	GO:0009914	121	0.051
regulation of phosphate metabolic process	GO:0019220	349	0.049
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.048
neuron development	GO:0048666	286	0.048
cellular cation homeostasis	GO:0030003	180	0.048
cell part morphogenesis	GO:0032990	123	0.047
metal ion homeostasis	GO:0055065	186	0.047
cellular homeostasis	GO:0019725	252	0.047
transcription from rna polymerase ii promoter	GO:0006366	252	0.045
rna metabolic process	GO:0016070	406	0.045
regulation of nucleotide metabolic process	GO:0006140	117	0.045
organonitrogen compound biosynthetic process	GO:1901566	167	0.044
apoptotic process	GO:0006915	381	0.044
negative regulation of hormone secretion	GO:0046888	46	0.044
homeostatic process	GO:0042592	331	0.043
secretion by cell	GO:0032940	248	0.043
circulatory system process	GO:0003013	183	0.043
defense response	GO:0006952	194	0.042
ion homeostasis	GO:0050801	212	0.042
calcium ion homeostasis	GO:0055074	162	0.042
regulation of rna metabolic process	GO:0051252	391	0.041
central nervous system development	GO:0007417	311	0.041
positive regulation of cellular biosynthetic process	GO:0031328	295	0.041
ribose phosphate metabolic process	GO:0019693	235	0.041
regulation of multicellular organismal development	GO:2000026	376	0.041
single organism reproductive process	GO:0044702	297	0.041
locomotion	GO:0040011	237	0.040
transcription dna templated	GO:0006351	377	0.040
proteolysis	GO:0006508	175	0.039
gastrulation	GO:0007369	2	0.039
nucleotide metabolic process	GO:0009117	279	0.039
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.039
localization of cell	GO:0051674	202	0.039
positive regulation of response to stimulus	GO:0048584	285	0.039
cellular amine metabolic process	GO:0044106	38	0.038
metal ion transport	GO:0030001	289	0.038
negative regulation of response to stimulus	GO:0048585	155	0.038
organophosphate biosynthetic process	GO:0090407	143	0.038
cytosolic calcium ion homeostasis	GO:0051480	140	0.038
rna biosynthetic process	GO:0032774	380	0.037
regulation of catalytic activity	GO:0050790	304	0.037
regulation of cell migration	GO:0030334	128	0.037
divalent inorganic cation transport	GO:0072511	134	0.037
reproduction	GO:0000003	245	0.036
multicellular organism reproduction	GO:0032504	233	0.035
cellular component biogenesis	GO:0044085	368	0.035
regulation of anatomical structure morphogenesis	GO:0022603	141	0.034
nucleic acid templated transcription	GO:0097659	379	0.034
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.034
positive regulation of cell proliferation	GO:0008284	249	0.034
cellular carbohydrate metabolic process	GO:0044262	72	0.034
hormone secretion	GO:0046879	115	0.034
negative regulation of protein transport	GO:0051224	17	0.033
cellular response to oxygen containing compound	GO:1901701	386	0.033
protein complex biogenesis	GO:0070271	263	0.033
single organism organelle organization	GO:1902589	180	0.033
lipid metabolic process	GO:0006629	283	0.033
regulation of system process	GO:0044057	208	0.033
cardiovascular system development	GO:0072358	134	0.032
regulation of peptide transport	GO:0090087	87	0.032
positive regulation of phosphate metabolic process	GO:0045937	262	0.032
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.032
catabolic process	GO:0009056	351	0.032
positive regulation of phosphorylation	GO:0042327	177	0.031
regulation of cellular component organization	GO:0051128	368	0.031
cellular ion homeostasis	GO:0006873	184	0.031
oxidation reduction process	GO:0055114	304	0.031
macromolecule localization	GO:0033036	252	0.031
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.031
cellular response to endogenous stimulus	GO:0071495	377	0.031
negative regulation of macromolecule metabolic process	GO:0010605	260	0.031
divalent inorganic cation homeostasis	GO:0072507	165	0.030
peptide secretion	GO:0002790	86	0.030
reproductive process	GO:0022414	372	0.030
secretion	GO:0046903	307	0.030
cell projection organization	GO:0030030	302	0.030
positive regulation of programmed cell death	GO:0043068	157	0.030
carbohydrate derivative metabolic process	GO:1901135	346	0.029
regulation of hormone levels	GO:0010817	187	0.029
regulation of neuron projection development	GO:0010975	161	0.029
cation transport	GO:0006812	382	0.029
wound healing	GO:0042060	122	0.029
positive regulation of gene expression	GO:0010628	244	0.029
multicellular organismal reproductive process	GO:0048609	233	0.029
lipid biosynthetic process	GO:0008610	128	0.028
negative regulation of biosynthetic process	GO:0009890	168	0.028
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.028
single organism carbohydrate metabolic process	GO:0044723	118	0.028
blood circulation	GO:0008015	183	0.028
regulation of protein metabolic process	GO:0051246	289	0.028
organelle organization	GO:0006996	266	0.028
positive regulation of secretion	GO:0051047	140	0.028
regulation of phosphorylation	GO:0042325	248	0.027
regulation of molecular function	GO:0065009	398	0.027
positive regulation of multicellular organismal process	GO:0051240	387	0.027
single organism catabolic process	GO:0044712	283	0.027
negative regulation of rna biosynthetic process	GO:1902679	118	0.027
cell morphogenesis involved in differentiation	GO:0000904	119	0.027
oxoacid metabolic process	GO:0043436	290	0.027
positive regulation of apoptotic process	GO:0043065	154	0.026
cellular metal ion homeostasis	GO:0006875	172	0.026
diencephalon development	GO:0021536	21	0.026
carboxylic acid metabolic process	GO:0019752	289	0.026
protein phosphorylation	GO:0006468	345	0.026
axon development	GO:0061564	96	0.026
regulation of metal ion transport	GO:0010959	118	0.026
regulation of cell differentiation	GO:0045595	320	0.025
regulation of neurogenesis	GO:0050767	247	0.025
regulation of protein phosphorylation	GO:0001932	183	0.025
nucleobase containing small molecule metabolic process	GO:0055086	316	0.025
regulation of peptide hormone secretion	GO:0090276	80	0.025
inflammatory response	GO:0006954	150	0.024
purine ribonucleotide biosynthetic process	GO:0009152	81	0.024
chemical homeostasis	GO:0048878	292	0.024
regulation of response to stress	GO:0080134	126	0.024
positive regulation of developmental process	GO:0051094	283	0.024
developmental process involved in reproduction	GO:0003006	159	0.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.023
cellular response to organonitrogen compound	GO:0071417	197	0.023
cell cell signaling	GO:0007267	335	0.023
response to decreased oxygen levels	GO:0036293	237	0.023
protein oligomerization	GO:0051259	191	0.022
response to radiation	GO:0009314	137	0.022
synaptic transmission	GO:0007268	235	0.022
protein heterooligomerization	GO:0051291	89	0.022
insulin secretion	GO:0030073	69	0.022
positive regulation of rna metabolic process	GO:0051254	203	0.022
regulation of signal transduction	GO:0009966	318	0.022
multi organism reproductive process	GO:0044703	262	0.022
regulation of cell proliferation	GO:0042127	359	0.021
carbohydrate derivative biosynthetic process	GO:1901137	124	0.021
cyclic nucleotide metabolic process	GO:0009187	80	0.021
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.021
response to hexose	GO:0009746	144	0.021
negative regulation of secretion	GO:0051048	82	0.021
regulation of cell motility	GO:2000145	131	0.021
cell projection morphogenesis	GO:0048858	123	0.020
amine metabolic process	GO:0009308	38	0.020
sexual reproduction	GO:0019953	148	0.020
regulation of cellular amino acid metabolic process	GO:0006521	2	0.020
regulation of cyclic nucleotide metabolic process	GO:0030799	51	0.020
cellular response to nitrogen compound	GO:1901699	210	0.020
neuronal action potential	GO:0019228	35	0.020
regulation of insulin secretion	GO:0050796	65	0.020
cellular component movement	GO:0006928	248	0.020
cellular lipid metabolic process	GO:0044255	208	0.020
negative regulation of signaling	GO:0023057	157	0.019
purine nucleotide metabolic process	GO:0006163	229	0.019
cell cycle	GO:0007049	101	0.019
positive regulation of protein metabolic process	GO:0051247	178	0.019
protein complex subunit organization	GO:0071822	302	0.019
regulation of cellular ketone metabolic process	GO:0010565	27	0.019
intracellular transport	GO:0046907	185	0.019
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.019
regulation of catabolic process	GO:0009894	113	0.019
transmission of nerve impulse	GO:0019226	42	0.019
cellular protein localization	GO:0034613	122	0.018
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.018
regulation of response to external stimulus	GO:0032101	106	0.018
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.018
intracellular protein transport	GO:0006886	79	0.018
cell motility	GO:0048870	202	0.018
glucan metabolic process	GO:0044042	23	0.018
regulation of cellular carbohydrate metabolic process	GO:0010675	39	0.018
cellular catabolic process	GO:0044248	295	0.018
ribonucleotide biosynthetic process	GO:0009260	85	0.017
organ morphogenesis	GO:0009887	75	0.017
positive regulation of cardiac muscle cell proliferation	GO:0060045	4	0.017
positive regulation of rna biosynthetic process	GO:1902680	197	0.017
positive regulation of purine nucleotide biosynthetic process	GO:1900373	36	0.017
nitrogen compound transport	GO:0071705	229	0.017
neuron projection morphogenesis	GO:0048812	122	0.017
ovulation cycle	GO:0042698	67	0.017
negative regulation of cell communication	GO:0010648	158	0.017
response to ketone	GO:1901654	182	0.017
cellular ketone metabolic process	GO:0042180	51	0.017
nuclear transport	GO:0051169	49	0.017
response to glucose	GO:0009749	136	0.017
immune response	GO:0006955	104	0.017
regulation of nervous system development	GO:0051960	264	0.017
glucose metabolic process	GO:0006006	52	0.017
positive regulation of cell communication	GO:0010647	271	0.016
negative regulation of cell proliferation	GO:0008285	119	0.016
carbohydrate metabolic process	GO:0005975	130	0.016
positive regulation of cell differentiation	GO:0045597	217	0.016
small gtpase mediated signal transduction	GO:0007264	36	0.016
regulation of cell development	GO:0060284	263	0.016
regulation of purine nucleotide metabolic process	GO:1900542	115	0.016
cell morphogenesis	GO:0000902	142	0.016
l glutamate import	GO:0051938	2	0.016
positive regulation of catalytic activity	GO:0043085	184	0.016
tongue morphogenesis	GO:0043587	3	0.016
peptide hormone secretion	GO:0030072	84	0.015
cellular component assembly	GO:0022607	360	0.015
protein transport	GO:0015031	132	0.015
reproductive system development	GO:0061458	128	0.015
negative regulation of innate immune response	GO:0045824	4	0.015
regulation of angiogenesis	GO:0045765	39	0.015
phospholipid biosynthetic process	GO:0008654	29	0.015
negative regulation of camp metabolic process	GO:0030815	14	0.015
nucleoside phosphate metabolic process	GO:0006753	283	0.015
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.015
cyclic purine nucleotide metabolic process	GO:0052652	62	0.015
protein import into nucleus	GO:0006606	35	0.015
response to inorganic substance	GO:0010035	377	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.015
response to estrogen	GO:0043627	232	0.015
ion transmembrane transport	GO:0034220	365	0.015
dna metabolic process	GO:0006259	96	0.015
negative regulation of cell death	GO:0060548	229	0.015
positive regulation of signal transduction	GO:0009967	175	0.015
positive regulation of cell death	GO:0010942	184	0.015
lipid transport	GO:0006869	61	0.015
gonad development	GO:0008406	104	0.015
growth	GO:0040007	165	0.015
positive regulation of transcription dna templated	GO:0045893	197	0.015
ribonucleotide metabolic process	GO:0009259	231	0.014
regulation of membrane potential	GO:0042391	110	0.014
muscle structure development	GO:0061061	87	0.014
nucleotide biosynthetic process	GO:0009165	98	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.014
response to oxygen levels	GO:0070482	265	0.014
cytoplasmic transport	GO:0016482	115	0.014
regulation of purine nucleotide biosynthetic process	GO:1900371	46	0.014
protein import	GO:0017038	37	0.014
neuropeptide signaling pathway	GO:0007218	29	0.014
protein processing	GO:0016485	68	0.014
regulation of cellular amine metabolic process	GO:0033238	8	0.014
cellular amino acid metabolic process	GO:0006520	107	0.014
mitotic cell cycle	GO:0000278	49	0.014
negative regulation of secretion by cell	GO:1903531	72	0.014
peptide transport	GO:0015833	97	0.014
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.014
gamete generation	GO:0007276	124	0.014
regulation of cell cycle	GO:0051726	73	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.014
purine ribonucleotide metabolic process	GO:0009150	227	0.014
negative regulation of molecular function	GO:0044092	133	0.014
myelination	GO:0042552	39	0.014
regulation of establishment of protein localization	GO:0070201	69	0.014
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
purine containing compound biosynthetic process	GO:0072522	85	0.014
protein maturation	GO:0051604	68	0.013
positive regulation of transport	GO:0051050	245	0.013
response to purine containing compound	GO:0014074	126	0.013
cofactor metabolic process	GO:0051186	95	0.013
regulation of ion transport	GO:0043269	245	0.013
negative regulation of rna metabolic process	GO:0051253	123	0.013
sensory perception	GO:0007600	101	0.013
forebrain neuron development	GO:0021884	3	0.013
negative regulation of protein metabolic process	GO:0051248	114	0.013
regulation of cellular component movement	GO:0051270	150	0.013
vascular process in circulatory system	GO:0003018	96	0.013
reactive nitrogen species metabolic process	GO:2001057	1	0.013
purine containing compound metabolic process	GO:0072521	253	0.013
monocarboxylic acid metabolic process	GO:0032787	152	0.013
nuclear import	GO:0051170	35	0.013
ras protein signal transduction	GO:0007265	29	0.013
fertilization	GO:0009566	3	0.013
cellular chemical homeostasis	GO:0055082	247	0.013
axonogenesis	GO:0007409	71	0.013
cellular response to oxygen levels	GO:0071453	60	0.013
regulation of protein targeting	GO:1903533	28	0.013
metanephric tubule morphogenesis	GO:0072173	2	0.013
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	51	0.013
reactive oxygen species metabolic process	GO:0072593	37	0.013
response to oxidative stress	GO:0006979	186	0.013
regulation of cell morphogenesis	GO:0022604	77	0.013
negative regulation of multicellular organismal process	GO:0051241	203	0.012
calcium ion transport	GO:0006816	131	0.012
response to estradiol	GO:0032355	164	0.012
striated muscle tissue development	GO:0014706	58	0.012
positive regulation of protein kinase b signaling	GO:0051897	10	0.012
regulation of protein import into nucleus	GO:0042306	24	0.012
sequestering of calcium ion	GO:0051208	8	0.012
regulation of camp metabolic process	GO:0030814	43	0.012
phospholipid metabolic process	GO:0006644	61	0.012
regulation of intracellular transport	GO:0032386	65	0.012
regulation of nucleotide biosynthetic process	GO:0030808	47	0.012
regulation of cell projection organization	GO:0031344	175	0.012
regulation of synaptic transmission	GO:0050804	141	0.012
negative regulation of phosphorus metabolic process	GO:0010563	80	0.012
nucleocytoplasmic transport	GO:0006913	48	0.012
cell cycle process	GO:0022402	57	0.012
visual learning	GO:0008542	8	0.012
regulation of g0 to g1 transition	GO:0070316	3	0.012
aromatic compound catabolic process	GO:0019439	168	0.012
carbohydrate biosynthetic process	GO:0016051	42	0.012
negative regulation of long term synaptic potentiation	GO:1900272	1	0.012
negative regulation of phosphate metabolic process	GO:0045936	80	0.012
response to activity	GO:0014823	73	0.012
positive regulation of cyclic nucleotide metabolic process	GO:0030801	37	0.012
peptidyl amino acid modification	GO:0018193	126	0.012
circadian rhythm	GO:0007623	88	0.012
positive regulation of intracellular signal transduction	GO:1902533	138	0.012
anatomical structure homeostasis	GO:0060249	29	0.012
maintenance of location	GO:0051235	17	0.012
negative regulation of transcription dna templated	GO:0045892	116	0.012
regulation of peptide secretion	GO:0002791	82	0.012
reactive oxygen species biosynthetic process	GO:1903409	8	0.011
response to hypoxia	GO:0001666	231	0.011
circulatory system development	GO:0072359	134	0.011
regulation of hydrolase activity	GO:0051336	143	0.011
reproductive structure development	GO:0048608	128	0.011
regulation of proteolysis	GO:0030162	66	0.011
regulation of smooth muscle cell proliferation	GO:0048660	75	0.011
organic acid metabolic process	GO:0006082	292	0.011
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.011
development of primary female sexual characteristics	GO:0046545	56	0.011
positive regulation of organelle organization	GO:0010638	48	0.011
divalent metal ion transport	GO:0070838	132	0.011
defense response to gram negative bacterium	GO:0050829	3	0.011
multi multicellular organism process	GO:0044706	138	0.011
regulation of cell growth	GO:0001558	85	0.011
positive regulation of ion transport	GO:0043270	94	0.011
regulation of dna metabolic process	GO:0051052	60	0.011
fat cell proliferation	GO:0070341	2	0.011
regulation of organelle organization	GO:0033043	80	0.011
single organism nuclear import	GO:1902593	35	0.011
positive regulation of cellular component organization	GO:0051130	200	0.011
regulation of cellular catabolic process	GO:0031329	101	0.011
coronary vasculature morphogenesis	GO:0060977	3	0.011
regulation of organ formation	GO:0003156	2	0.011
nucleoside phosphate biosynthetic process	GO:1901293	102	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.011
positive regulation of protein phosphorylation	GO:0001934	135	0.011
positive regulation of secretion by cell	GO:1903532	128	0.011
tolerance induction dependent upon immune response	GO:0002461	2	0.011
generation of precursor metabolites and energy	GO:0006091	62	0.011
developmental induction	GO:0031128	2	0.011
amide transport	GO:0042886	105	0.011
regulation of blood circulation	GO:1903522	110	0.011
ribose phosphate biosynthetic process	GO:0046390	87	0.011
cellular polysaccharide metabolic process	GO:0044264	23	0.011
single organism intracellular transport	GO:1902582	166	0.011
spermatogenesis	GO:0007283	99	0.011
regulation of epithelial cell proliferation	GO:0050678	49	0.010
cellular response to stress	GO:0033554	269	0.010
endoplasmic reticulum membrane organization	GO:0090158	1	0.010
negative regulation of intracellular signal transduction	GO:1902532	38	0.010
positive regulation of neuron differentiation	GO:0045666	126	0.010
organic hydroxy compound biosynthetic process	GO:1901617	51	0.010
regulation of cellular protein metabolic process	GO:0032268	267	0.010
positive regulation of cellular protein metabolic process	GO:0032270	167	0.010
phototransduction visible light	GO:0007603	2	0.010
cellular macromolecule localization	GO:0070727	122	0.010
epithelial cell proliferation	GO:0050673	54	0.010
skeletal system development	GO:0001501	41	0.010
neurological system process	GO:0050877	219	0.010
transmembrane transport	GO:0055085	412	0.010
glandular epithelial cell differentiation	GO:0002067	4	0.010
cyclic nucleotide biosynthetic process	GO:0009190	63	0.010
angiogenesis involved in coronary vascular morphogenesis	GO:0060978	3	0.010
cellular response to hypoxia	GO:0071456	51	0.010
positive regulation of neuron projection development	GO:0010976	99	0.010
regulation of growth	GO:0040008	105	0.010

Trim17 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
eye and adnexa disease	DOID:1492	0.145
nervous system disease	DOID:863	0.145
disease of anatomical entity	DOID:7	0.145
sensory system disease	DOID:0050155	0.145
eye disease	DOID:5614	0.120
retinal disease	DOID:5679	0.050
retinal degeneration	DOID:8466	0.012

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