Rattus norvegicus

19 known processes

Clcnkb

chloride channel Kb

(Aliases: Clcnk1l,Clck2,ClC-K2L)

Clcnkb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transmembrane transportGO:00986552630.508
anion transportGO:00068201780.365
regulation of ion transportGO:00432692450.284
Rat
regulation of system processGO:00440572080.253
metal ion transportGO:00300012890.243
cellular response to nitrogen compoundGO:19016992100.235
homeostatic processGO:00425923310.223
organophosphate metabolic processGO:00196373700.220
ion homeostasisGO:00508012120.205
ion transmembrane transportGO:00342203650.188
sodium ion transportGO:0006814820.175
blood circulationGO:00080151830.172
chemical homeostasisGO:00488782920.164
vascular process in circulatory systemGO:0003018960.163
sodium ion transmembrane transportGO:0035725670.154
agingGO:00075682410.145
response to purine containing compoundGO:00140741260.145
inorganic ion transmembrane transportGO:00986602290.141
cation homeostasisGO:00550801950.140
organonitrogen compound biosynthetic processGO:19015661670.137
monovalent inorganic cation transportGO:00156721720.135
cellular homeostasisGO:00197252520.132
tissue morphogenesisGO:0048729220.132
cellular cation homeostasisGO:00300031800.127
metal ion homeostasisGO:00550651860.122
circulatory system processGO:00030131830.121
cellular response to abiotic stimulusGO:0071214850.120
growthGO:00400071650.117
cation transportGO:00068123820.115
regulation of cellular component organizationGO:00511283680.110
cellular component biogenesisGO:00440853680.110
cellular response to oxygen containing compoundGO:19017013860.099
response to campGO:0051591910.098
response to organophosphorusGO:00466831020.096
apoptotic processGO:00069153810.095
cellular chemical homeostasisGO:00550822470.093
response to acid chemicalGO:00011012220.087
Rat
heart processGO:0003015570.083
regulation of cell proliferationGO:00421273590.080
cellular response to organonitrogen compoundGO:00714171970.080
cellular metal ion homeostasisGO:00068751720.079
inorganic cation transmembrane transportGO:00986622020.078
transmembrane transportGO:00550854120.077
cardiac muscle contractionGO:0060048270.075
central nervous system developmentGO:00074173110.073
regulation of homeostatic processGO:00328441010.073
response to inorganic substanceGO:00100353770.073
Rat
brain developmentGO:00074202470.072
cellular response to organic cyclic compoundGO:00714072020.072
single organism biosynthetic processGO:00447113420.068
cellular calcium ion homeostasisGO:00068741600.067
carboxylic acid metabolic processGO:00197522890.067
negative regulation of cell proliferationGO:00082851190.067
cellular divalent inorganic cation homeostasisGO:00725031620.067
neurological system processGO:00508772190.066
action potentialGO:0001508540.066
response to mechanical stimulusGO:00096121340.065
rhythmic processGO:00485111560.064
regulation of phosphate metabolic processGO:00192203490.064
single organism reproductive processGO:00447022970.063
cellular response to endogenous stimulusGO:00714953770.063
cell growthGO:00160491040.063
heart contractionGO:0060047570.061
urogenital system developmentGO:0001655780.061
Rat
reproductive processGO:00224143720.060
ovulation cycle processGO:0022602500.059
carboxylic acid transportGO:00469421150.058
regulation of phosphorus metabolic processGO:00511743490.058
organic acid biosynthetic processGO:0016053830.057
regulation of immune system processGO:00026821230.057
muscle contractionGO:0006936880.055
intracellular signal transductionGO:00355563140.055
regulation of multicellular organismal developmentGO:20000263760.055
organic anion transportGO:00157111320.053
immune system processGO:00023762040.053
sensory perceptionGO:00076001010.052
calcium ion transportGO:00068161310.052
organophosphate biosynthetic processGO:00904071430.050
regulation of heart contractionGO:0008016480.048
head developmentGO:00603222470.046
tissue developmentGO:00098882520.046
multi organism reproductive processGO:00447032620.046
regulation of metal ion transportGO:00109591180.045
regulation of anatomical structure sizeGO:00900661350.045
response to nutrient levelsGO:00316673700.043
divalent inorganic cation homeostasisGO:00725071650.043
small molecule biosynthetic processGO:00442831240.042
negative regulation of cell differentiationGO:0045596990.042
carboxylic acid biosynthetic processGO:0046394830.042
regulation of endocytosisGO:0030100420.042
acid secretionGO:0046717480.042
organic acid metabolic processGO:00060822920.042
anatomical structure morphogenesisGO:00096532980.041
response to metal ionGO:00100382530.040
Rat
regulation of blood vessel sizeGO:0050880890.040
response to molecule of bacterial originGO:00022371940.040
response to extracellular stimulusGO:00099913800.040
response to estrogenGO:00436272320.039
negative regulation of cell developmentGO:0010721820.039
cognitionGO:0050890920.039
regulation of blood circulationGO:19035221100.038
defense responseGO:00069521940.038
macromolecular complex assemblyGO:00650032730.038
protein complex biogenesisGO:00702712630.038
behaviorGO:00076102050.038
cellular response to hormone stimulusGO:00328702470.038
regulation of programmed cell deathGO:00430673410.037
calcium ion transport into cytosolGO:0060402380.037
amine metabolic processGO:0009308380.037
renal system developmentGO:0072001670.037
Rat
multicellular organismal signalingGO:0035637440.037
multicellular organism reproductionGO:00325042330.037
regulation of membrane potentialGO:00423911100.036
purine ribonucleotide metabolic processGO:00091502270.036
cytosolic calcium ion homeostasisGO:00514801400.035
response to carbohydrateGO:00097431830.035
nucleoside phosphate metabolic processGO:00067532830.034
nitrogen compound transportGO:00717052290.034
response to vitaminGO:00332731310.033
cellular ion homeostasisGO:00068731840.033
response to external biotic stimulusGO:00432072210.033
organic acid transportGO:00158491160.033
ribose phosphate metabolic processGO:00196932350.033
regulation of molecular functionGO:00650093980.033
response to oxygen levelsGO:00704822650.033
fatty acid metabolic processGO:0006631990.032
cellular response to campGO:0071320260.032
regulation of organic acid transportGO:0032890350.031
response to hyperoxiaGO:0055093450.031
regulation of smooth muscle cell proliferationGO:0048660750.031
organ formationGO:004864530.031
regulation of phagocytosisGO:0050764130.031
regulation of fat cell proliferationGO:007034410.031
cellular response to mechanical stimulusGO:0071260480.031
regulation of muscle system processGO:0090257790.030
gonad developmentGO:00084061040.030
regulation of organelle organizationGO:0033043800.030
oxoacid metabolic processGO:00434362900.030
transmission of nerve impulseGO:0019226420.030
programmed cell deathGO:00125013920.030
cell communication involved in cardiac conductionGO:008606520.030
single organism catabolic processGO:00447122830.029
muscle cell proliferationGO:0033002840.029
response to growth factorGO:00708481890.029
cellular response to external stimulusGO:00714961180.029
nucleotide metabolic processGO:00091172790.029
reproductionGO:00000032450.028
regulation of blood pressureGO:0008217830.028
positive regulation of biosynthetic processGO:00098913190.028
cellular component assemblyGO:00226073600.027
fatty acid biosynthetic processGO:0006633330.027
response to oxidative stressGO:00069791860.027
response to lipopolysaccharideGO:00324961910.027
developmental process involved in reproductionGO:00030061590.027
positive regulation of synaptic transmission gabaergicGO:003223090.026
muscle system processGO:00030121150.026
purine nucleotide metabolic processGO:00061632290.026
positive regulation of cell deathGO:00109421840.026
small gtpase mediated signal transductionGO:0007264360.026
maintenance of locationGO:0051235170.026
peptide transportGO:0015833970.026
divalent inorganic cation transportGO:00725111340.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
response to insulinGO:00328681330.026
positive regulation of nitrogen compound metabolic processGO:00511733340.025
sequestering of calcium ionGO:005120880.025
regulation of tube sizeGO:0035150890.025
kidney developmentGO:0001822670.025
Rat
multicellular organismal reproductive processGO:00486092330.025
endocytosisGO:0006897840.024
cellular amine metabolic processGO:0044106380.024
protein complex subunit organizationGO:00718223020.024
regulation of neuron differentiationGO:00456642080.024
regulation of organ formationGO:000315620.024
macromolecular complex subunit organizationGO:00439333390.024
response to monosaccharideGO:00342841590.024
specification of organ identityGO:001009220.024
regulation of ion homeostasisGO:2000021630.024
eye developmentGO:0001654500.023
muscle structure developmentGO:0061061870.023
protein oligomerizationGO:00512591910.023
positive regulation of macromolecule biosynthetic processGO:00105572470.023
ureteric bud developmentGO:0001657140.023
positive regulation of cellular component organizationGO:00511302000.023
epithelium developmentGO:0060429960.023
cardiac conductionGO:006133720.022
single organism intracellular transportGO:19025821660.022
regulation of transcription dna templatedGO:00063553740.022
regulation of cytoskeleton organizationGO:0051493490.022
positive regulation of muscle contractionGO:0045933220.022
sequestering of metal ionGO:005123890.022
regulation of signal transductionGO:00099663180.022
neuron projection developmentGO:00311752730.022
organic hydroxy compound metabolic processGO:19016151150.021
locomotionGO:00400112370.021
response to tumor necrosis factorGO:0034612560.021
intracellular transportGO:00469071850.021
leukotriene biosynthetic processGO:001937030.021
regulation of ion transmembrane transportGO:00347651210.020
Rat
sodium ion homeostasisGO:0055078230.020
response to other organismGO:00517072200.020
response to calcium ionGO:0051592590.020
Rat
localization of cellGO:00516742020.020
response to decreased oxygen levelsGO:00362932370.020
divalent metal ion transportGO:00708381320.020
positive regulation of apoptotic processGO:00430651540.020
cellular component movementGO:00069282480.020
response to osmotic stressGO:0006970420.020
nucleobase containing small molecule metabolic processGO:00550863160.020
camera type eye developmentGO:0043010480.019
response to ketoneGO:19016541820.019
regulation of cellular amino acid metabolic processGO:000652120.019
lens development in camera type eyeGO:0002088130.019
g protein coupled receptor signaling pathwayGO:00071862420.019
positive regulation of developmental processGO:00510942830.019
development of primary sexual characteristicsGO:00451371070.019
positive regulation of biomineral tissue developmentGO:007016940.019
regulation of apoptotic processGO:00429813350.019
positive regulation of phosphorus metabolic processGO:00105622620.019
negative regulation of kidney developmentGO:009018520.019
positive regulation of signalingGO:00230562700.019
protein complex assemblyGO:00064612630.018
cell migrationGO:00164771970.018
regulation of cellular protein metabolic processGO:00322682670.018
positive regulation of fat cell proliferationGO:007034610.018
steroid hormone mediated signaling pathwayGO:004340180.018
lipid biosynthetic processGO:00086101280.018
organonitrogen compound catabolic processGO:19015651790.018
transcription from rna polymerase ii promoterGO:00063662520.018
micturitionGO:006007340.018
negative regulation of nervous system developmentGO:0051961790.018
positive regulation of multicellular organismal processGO:00512403870.018
single organismal cell cell adhesionGO:0016337420.018
regulation of rna biosynthetic processGO:20011413810.018
striated muscle contractionGO:0006941440.018
regulation of sodium ion transmembrane transporter activityGO:200064940.018
negative regulation of secretionGO:0051048820.018
positive regulation of molecular functionGO:00440932300.017
regulation of nervous system developmentGO:00519602640.017
regulation of sodium ion transportGO:0002028210.017
response to cytokineGO:00340972150.017
reproductive structure developmentGO:00486081280.017
ribonucleoside metabolic processGO:00091191740.017
chemosensory behaviorGO:000763520.016
cytosolic calcium ion transportGO:0060401390.016
negative regulation of transporter activityGO:0032410130.016
organic hydroxy compound biosynthetic processGO:1901617510.016
regulation of cellular component biogenesisGO:0044087860.016
tube developmentGO:0035295890.016
Rat
response to nutrientGO:00075842480.016
regulation of heart rateGO:0002027160.016
smooth muscle cell proliferationGO:0048659770.016
renal system processGO:0003014400.016
behavioral response to nicotineGO:003509520.016
regulation of cardiac muscle contractionGO:0055117170.016
embryo developmentGO:0009790490.016
reproductive system developmentGO:00614581280.016
negative regulation of signal transductionGO:0009968830.016
retina morphogenesis in camera type eyeGO:006004210.016
ovulation cycleGO:0042698670.016
mesenchymal to epithelial transitionGO:006023130.016
regulation of excretionGO:0044062210.016
purine containing compound metabolic processGO:00725212530.016
response to hypoxiaGO:00016662310.016
protein localizationGO:00081041910.016
cytoplasmic transportGO:00164821150.016
learning or memoryGO:0007611900.015
positive regulation of gene expressionGO:00106282440.015
monovalent inorganic cation homeostasisGO:0055067360.015
hair cycle processGO:002240520.015
phospholipid biosynthetic processGO:0008654290.015
hormone transportGO:00099141210.015
single organism cell adhesionGO:0098602460.015
nephron tubule developmentGO:0072080120.015
carbohydrate derivative catabolic processGO:19011361470.015
positive regulation of blood circulationGO:1903524650.015
axis specificationGO:000979840.015
rna biosynthetic processGO:00327743800.015
neuronal action potentialGO:0019228350.015
negative regulation of transportGO:00510511360.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
actin filament based movementGO:0030048160.015
organ morphogenesisGO:0009887750.015
response to electrical stimulusGO:0051602560.015
positive regulation of endocytosisGO:0045807280.015
regulation of phosphorylationGO:00423252480.015
circadian rhythmGO:0007623880.015
tissue remodelingGO:0048771400.015
ribonucleotide biosynthetic processGO:0009260850.014
myeloid leukocyte differentiationGO:0002573200.014
phospholipid metabolic processGO:0006644610.014
response to glucoseGO:00097491360.014
organ growthGO:0035265240.014
multi multicellular organism processGO:00447061380.014
lipid metabolic processGO:00066292830.014
negative regulation of cell communicationGO:00106481580.014
proteolysisGO:00065081750.014
regulation of amino acid transportGO:0051955250.014
biological adhesionGO:00226101100.014
response to estradiolGO:00323551640.014
single organism behaviorGO:00447081300.014
membrane organizationGO:0061024940.014
regulation of cell differentiationGO:00455953200.014
cellular response to gonadotropin stimulusGO:0071371170.014
cellular ketone metabolic processGO:0042180510.014
actin filament based processGO:0030029860.014
actin mediated cell contractionGO:0070252120.014
regulation of calcium ion transmembrane transportGO:1903169180.014
negative regulation of metanephros developmentGO:007221720.014
negative regulation of hormone secretionGO:0046888460.014
cardiac muscle cell contractionGO:0086003100.013
ribonucleotide metabolic processGO:00092592310.013
alpha amino acid metabolic processGO:1901605710.013
response to hexoseGO:00097461440.013
brown fat cell proliferationGO:007034220.013
positive regulation of cell proliferationGO:00082842490.013
regulation of inflammatory responseGO:0050727480.013
potassium ion transmembrane transportGO:0071805710.013
odontogenesisGO:0042476320.013
cell activationGO:0001775970.013
positive regulation of epithelial cell proliferationGO:0050679320.013
cellular response to drugGO:0035690300.013
dna metabolic processGO:0006259960.013
mesonephric tubule developmentGO:0072164140.013
regulation of cell projection organizationGO:00313441750.013
positive regulation of programmed cell deathGO:00430681570.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
ras protein signal transductionGO:0007265290.013
male mating behaviorGO:006017930.013
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.012
response to increased oxygen levelsGO:0036296450.012
kidney epithelium developmentGO:0072073190.012
morphogenesis of an epitheliumGO:0002009200.012
vasoconstrictionGO:0042310540.012
regulation of cellular amine metabolic processGO:003323880.012
camp metabolic processGO:0046058630.012
nucleotide biosynthetic processGO:0009165980.012
protein tetramerizationGO:0051262380.012
cellular modified amino acid metabolic processGO:0006575610.012
negative regulation of intracellular signal transductionGO:1902532380.012
nucleoside phosphate catabolic processGO:19012921400.012
glycerophospholipid metabolic processGO:0006650470.012
regulation of membrane repolarizationGO:006030610.012
regulation of secretionGO:00510462240.012
leukocyte differentiationGO:0002521300.012
sensory perception of painGO:0019233730.012
regulation of peptide hormone secretionGO:0090276800.012
cellular response to lipidGO:00713962010.012
mesonephros developmentGO:0001823140.012
multicellular organismal homeostasisGO:0048871490.012
molting cycleGO:004230330.012
organ inductionGO:000175910.012
cell adhesionGO:00071551100.012
regulation of nucleotide metabolic processGO:00061401170.012
response to anoxiaGO:003405940.012
cellular response to acid chemicalGO:0071229750.012
neuron developmentGO:00486662860.012
negative regulation of calcium ion transport into cytosolGO:001052340.012
cellular amino acid metabolic processGO:00065201070.012
amino acid transportGO:0006865700.011
cellular amide metabolic processGO:0043603440.011
response to peptide hormoneGO:00434342780.011
nucleic acid templated transcriptionGO:00976593790.011
regulation of actin filament based processGO:0032970420.011
cellular modified amino acid biosynthetic processGO:0042398180.011
cellular response to growth factor stimulusGO:00713631620.011
cell differentiation involved in kidney developmentGO:006100540.011
positive regulation of ion transportGO:0043270940.011
regulation of cell developmentGO:00602842630.011
thyroid gland developmentGO:003087810.011
regulation of defense responseGO:0031347680.011
regulation of protein metabolic processGO:00512462890.011
regulation of cellular ketone metabolic processGO:0010565270.011
response to gonadotropinGO:0034698340.011
leukocyte cell cell adhesionGO:000715940.011
calcium ion homeostasisGO:00550741620.011
lipid transportGO:0006869610.011
response to activityGO:0014823730.011
carbohydrate derivative metabolic processGO:19011353460.011
regulation of anion transportGO:0044070430.011
Rat
negative regulation of multicellular organismal processGO:00512412030.011
negative regulation of neuron differentiationGO:0045665620.011
regulation of vesicle mediated transportGO:0060627810.011
regulation of body fluid levelsGO:0050878900.011
Rat
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.011
protein phosphorylationGO:00064683450.011
cardiovascular system developmentGO:00723581340.011
positive regulation of cellular amine metabolic processGO:003324030.011
regulation of cyclic nucleotide metabolic processGO:0030799510.011
gastrulationGO:000736920.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
rna metabolic processGO:00160704060.011
phagocytosisGO:0006909170.011
negative regulation of ion transportGO:0043271510.011
positive regulation of cellular component biogenesisGO:0044089550.011
embryonic pattern specificationGO:000988010.011
cellular nitrogen compound catabolic processGO:00442701630.011
cellular response to stressGO:00335542690.011
positive regulation of rna metabolic processGO:00512542030.011
negative regulation of response to stimulusGO:00485851550.011
negative regulation of homeostatic processGO:0032845470.011
positive regulation of peptide hormone secretionGO:0090277500.011
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.011
cellular response to insulin stimulusGO:0032869810.011
negative regulation of organic acid transportGO:0032891140.011
reactive oxygen species biosynthetic processGO:190340980.010
regulation of behaviorGO:0050795610.010
reactive oxygen species metabolic processGO:0072593370.010
positive regulation of phosphorylationGO:00423271770.010
developmental growthGO:00485891000.010
positive regulation of smooth muscle contractionGO:0045987180.010
metanephric epithelium developmentGO:007220740.010
coronary vasculature morphogenesisGO:006097730.010
regulation of locomotionGO:00400121480.010
organic substance catabolic processGO:19015753160.010
rho protein signal transductionGO:0007266110.010
nucleobase containing compound catabolic processGO:00346551520.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
grooming behaviorGO:000762540.010

Clcnkb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.515
Human
urinary system diseaseDOID:1800.515
Human
kidney diseaseDOID:55700.497
Human
renal tubular transport diseaseDOID:44700.388
Human
nervous system diseaseDOID:86300.097
sensory system diseaseDOID:005015500.097
eye diseaseDOID:561400.048
eye and adnexa diseaseDOID:149200.048
retinal diseaseDOID:567900.048
retinal degenerationDOID:846600.031
endocrine system diseaseDOID:2800.023
musculoskeletal system diseaseDOID:1700.010
retinitis pigmentosaDOID:1058400.010