IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Pcdha13

protocadherin alpha 13

(Aliases: Cnr5)

Entrez: 116742
RGD: 620751
UniProtKB: I6LBW4

Process Predictions
Disease Predictions

Pcdha13 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
neuron differentiation	GO:0030182	368	0.130
negative regulation of nervous system development	GO:0051961	79	0.102
cellular component morphogenesis	GO:0032989	155	0.075
axon development	GO:0061564	96	0.072
synaptic growth at neuromuscular junction	GO:0051124	1	0.071
neuron development	GO:0048666	286	0.069
inorganic ion transmembrane transport	GO:0098660	229	0.066
neuron projection development	GO:0031175	273	0.066
nucleotide metabolic process	GO:0009117	279	0.064
negative regulation of multicellular organismal process	GO:0051241	203	0.058
negative regulation of biosynthetic process	GO:0009890	168	0.058
cell projection morphogenesis	GO:0048858	123	0.057
regulation of axonogenesis	GO:0050770	37	0.056
cell part morphogenesis	GO:0032990	123	0.054
regulation of neuron projection development	GO:0010975	161	0.054
mesoderm development	GO:0007498	2	0.054
regulation of neurogenesis	GO:0050767	247	0.054
cell cell signaling	GO:0007267	335	0.051
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.048
cell morphogenesis involved in differentiation	GO:0000904	119	0.048
regulation of nervous system development	GO:0051960	264	0.047
cellular component biogenesis	GO:0044085	368	0.046
negative regulation of neurogenesis	GO:0050768	78	0.045
reproductive process	GO:0022414	372	0.045
synaptic transmission	GO:0007268	235	0.045
organonitrogen compound biosynthetic process	GO:1901566	167	0.042
positive regulation of multicellular organismal process	GO:0051240	387	0.042
rna metabolic process	GO:0016070	406	0.042
brain development	GO:0007420	247	0.042
purine ribonucleotide metabolic process	GO:0009150	227	0.042
negative regulation of cell development	GO:0010721	82	0.041
central nervous system development	GO:0007417	311	0.040
transcription dna templated	GO:0006351	377	0.040
nucleic acid templated transcription	GO:0097659	379	0.039
response to cytokine	GO:0034097	215	0.038
regulation of response to external stimulus	GO:0032101	106	0.038
regulation of rna metabolic process	GO:0051252	391	0.038
negative regulation of cell differentiation	GO:0045596	99	0.037
head development	GO:0060322	247	0.037
cell projection organization	GO:0030030	302	0.037
nucleobase containing small molecule metabolic process	GO:0055086	316	0.036
regulation of transcription dna templated	GO:0006355	374	0.036
regulation of nucleic acid templated transcription	GO:1903506	380	0.036
neuron projection morphogenesis	GO:0048812	122	0.036
positive regulation of cell development	GO:0010720	176	0.035
cellular catabolic process	GO:0044248	295	0.035
axonogenesis	GO:0007409	71	0.035
regulation of phosphate metabolic process	GO:0019220	349	0.034
protein complex biogenesis	GO:0070271	263	0.034
anterior posterior pattern specification	GO:0009952	1	0.034
negative regulation of developmental process	GO:0051093	125	0.034
macromolecular complex assembly	GO:0065003	273	0.034
synaptic vesicle localization	GO:0097479	24	0.033
regulation of multicellular organismal development	GO:2000026	376	0.033
positive regulation of nervous system development	GO:0051962	178	0.032
purine nucleotide biosynthetic process	GO:0006164	83	0.032
nucleoside phosphate metabolic process	GO:0006753	283	0.031
cerebral cortex tangential migration	GO:0021800	1	0.031
defecation	GO:0030421	1	0.031
carbohydrate derivative metabolic process	GO:1901135	346	0.031
cell motility	GO:0048870	202	0.031
apoptotic process	GO:0006915	381	0.030
ribonucleotide metabolic process	GO:0009259	231	0.030
regulation of cellular component organization	GO:0051128	368	0.030
cell morphogenesis	GO:0000902	142	0.030
negative regulation of cellular component organization	GO:0051129	83	0.030
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.030
positive regulation of cellular biosynthetic process	GO:0031328	295	0.030
organic acid metabolic process	GO:0006082	292	0.029
carboxylic acid biosynthetic process	GO:0046394	83	0.028
regulation of signal transduction	GO:0009966	318	0.028
cellular ketone metabolic process	GO:0042180	51	0.028
regulation of locomotion	GO:0040012	148	0.028
regulation of cellular ketone metabolic process	GO:0010565	27	0.028
ribose phosphate metabolic process	GO:0019693	235	0.028
regulation of neuron differentiation	GO:0045664	208	0.028
purine nucleotide metabolic process	GO:0006163	229	0.027
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.027
axon guidance	GO:0007411	24	0.027
positive regulation of neuron migration	GO:2001224	2	0.026
intracellular signal transduction	GO:0035556	314	0.026
transmembrane transport	GO:0055085	412	0.026
regulation of molecular function	GO:0065009	398	0.025
cellular component movement	GO:0006928	248	0.025
rna biosynthetic process	GO:0032774	380	0.025
neuromuscular process	GO:0050905	2	0.025
positive regulation of gene expression	GO:0010628	244	0.025
cellular amino acid metabolic process	GO:0006520	107	0.025
behavior	GO:0007610	205	0.025
single organism organelle organization	GO:1902589	180	0.025
negative regulation of neuron differentiation	GO:0045665	62	0.025
positive regulation of neurogenesis	GO:0050769	165	0.024
single organism reproductive process	GO:0044702	297	0.024
olfactory bulb interneuron differentiation	GO:0021889	1	0.024
negative regulation of neuron projection development	GO:0010977	46	0.024
positive regulation of developmental process	GO:0051094	283	0.024
negative regulation of gene expression	GO:0010629	199	0.024
locomotion	GO:0040011	237	0.024
regulation of cell projection organization	GO:0031344	175	0.024
multicellular organism growth	GO:0035264	1	0.023
regulation of rna biosynthetic process	GO:2001141	381	0.023
ribose phosphate biosynthetic process	GO:0046390	87	0.023
positive regulation of cellular component organization	GO:0051130	200	0.023
hormone transport	GO:0009914	121	0.023
regulation of cellular amino acid metabolic process	GO:0006521	2	0.023
motor neuron axon guidance	GO:0008045	1	0.023
dendrite development	GO:0016358	72	0.022
single organismal cell cell adhesion	GO:0016337	42	0.022
single organism biosynthetic process	GO:0044711	342	0.022
spinal cord development	GO:0021510	27	0.022
ribonucleotide biosynthetic process	GO:0009260	85	0.022
small molecule biosynthetic process	GO:0044283	124	0.022
carbohydrate derivative biosynthetic process	GO:1901137	124	0.022
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.022
carboxylic acid metabolic process	GO:0019752	289	0.021
protein heterooligomerization	GO:0051291	89	0.021
cellular amine metabolic process	GO:0044106	38	0.021
organic cyclic compound catabolic process	GO:1901361	175	0.021
biological adhesion	GO:0022610	110	0.021
axon midline choice point recognition	GO:0016199	2	0.021
negative regulation of response to stimulus	GO:0048585	155	0.021
response to wounding	GO:0009611	254	0.021
positive regulation of neuron projection development	GO:0010976	99	0.021
insulin secretion	GO:0030073	69	0.021
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.020
vesicle mediated transport	GO:0016192	181	0.020
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.020
negative regulation of macromolecule metabolic process	GO:0010605	260	0.020
multicellular organism reproduction	GO:0032504	233	0.020
central nervous system neuron differentiation	GO:0021953	17	0.020
amine metabolic process	GO:0009308	38	0.020
neurological system process	GO:0050877	219	0.020
negative regulation of rna metabolic process	GO:0051253	123	0.020
regulation of apoptotic process	GO:0042981	335	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.020
growth	GO:0040007	165	0.020
oxoacid metabolic process	GO:0043436	290	0.020
purine ribonucleotide biosynthetic process	GO:0009152	81	0.019
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.019
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.019
negative regulation of transcription dna templated	GO:0045892	116	0.019
organonitrogen compound catabolic process	GO:1901565	179	0.019
ion transmembrane transport	GO:0034220	365	0.019
protein complex subunit organization	GO:0071822	302	0.019
peptidyl amino acid modification	GO:0018193	126	0.019
regulation of phosphorus metabolic process	GO:0051174	349	0.019
multicellular organismal reproductive process	GO:0048609	233	0.019
cell adhesion	GO:0007155	110	0.019
protein phosphorylation	GO:0006468	345	0.019
nucleotide biosynthetic process	GO:0009165	98	0.019
neuromuscular synaptic transmission	GO:0007274	2	0.019
homeostatic process	GO:0042592	331	0.019
positive regulation of phosphorus metabolic process	GO:0010562	262	0.019
regulation of cell development	GO:0060284	263	0.019
regulation of dendrite development	GO:0050773	59	0.019
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.018
nucleoside phosphate biosynthetic process	GO:1901293	102	0.018
single organism membrane organization	GO:0044802	74	0.018
regulation of hormone levels	GO:0010817	187	0.018
positive regulation of cell differentiation	GO:0045597	217	0.018
positive regulation of cell projection organization	GO:0031346	111	0.018
reproduction	GO:0000003	245	0.018
regulation of cellular amine metabolic process	GO:0033238	8	0.018
tangential migration from the subventricular zone to the olfactory bulb	GO:0022028	1	0.018
macromolecular complex subunit organization	GO:0043933	339	0.018
cation transmembrane transport	GO:0098655	263	0.018
response to inorganic substance	GO:0010035	377	0.018
cellular component assembly	GO:0022607	360	0.018
organelle localization	GO:0051640	55	0.018
multicellular organismal signaling	GO:0035637	44	0.017
axon choice point recognition	GO:0016198	2	0.017
developmental growth	GO:0048589	100	0.017
camera type eye development	GO:0043010	48	0.017
calcium mediated signaling using intracellular calcium source	GO:0035584	1	0.017
gastrulation	GO:0007369	2	0.017
negative regulation of metabolic process	GO:0009892	331	0.017
response to acid chemical	GO:0001101	222	0.017
positive regulation of cellular amine metabolic process	GO:0033240	3	0.016
organic substance catabolic process	GO:1901575	316	0.016
cellular response to endogenous stimulus	GO:0071495	377	0.016
regulation of cellular component movement	GO:0051270	150	0.016
positive regulation of transport	GO:0051050	245	0.016
transmission of nerve impulse	GO:0019226	42	0.015
rhythmic process	GO:0048511	156	0.015
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.015
regulation of anatomical structure size	GO:0090066	135	0.015
neuron projection extension	GO:1990138	26	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.015
heart morphogenesis	GO:0003007	3	0.015
neuron neuron synaptic transmission	GO:0007270	60	0.015
protein complex assembly	GO:0006461	263	0.015
sexual reproduction	GO:0019953	148	0.015
amino acid transport	GO:0006865	70	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.015
cellular response to oxygen containing compound	GO:1901701	386	0.015
regulation of membrane potential	GO:0042391	110	0.015
actin crosslink formation	GO:0051764	3	0.015
negative regulation of programmed cell death	GO:0043069	183	0.015
cell migration	GO:0016477	197	0.015
glial cell differentiation	GO:0010001	65	0.014
synapse assembly	GO:0007416	29	0.014
regulation of programmed cell death	GO:0043067	341	0.014
regulation of hormone secretion	GO:0046883	106	0.014
positive regulation of rna biosynthetic process	GO:1902680	197	0.014
anion transport	GO:0006820	178	0.014
cyclic nucleotide metabolic process	GO:0009187	80	0.014
cell growth	GO:0016049	104	0.014
nitrogen compound transport	GO:0071705	229	0.014
regulation of ion transport	GO:0043269	245	0.014
catabolic process	GO:0009056	351	0.014
regulation of nucleotide metabolic process	GO:0006140	117	0.014
action potential	GO:0001508	54	0.014
positive regulation of neuron differentiation	GO:0045666	126	0.014
negative regulation of cell projection organization	GO:0031345	50	0.014
purine containing compound biosynthetic process	GO:0072522	85	0.014
programmed cell death	GO:0012501	392	0.014
purine containing compound metabolic process	GO:0072521	253	0.014
negative regulation of cell death	GO:0060548	229	0.014
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.014
protein oligomerization	GO:0051259	191	0.014
hair cycle	GO:0042633	3	0.013
synaptic vesicle transport	GO:0048489	23	0.013
multi organism reproductive process	GO:0044703	262	0.013
neuron projection guidance	GO:0097485	24	0.013
cellular response to lipid	GO:0071396	201	0.013
ion homeostasis	GO:0050801	212	0.013
establishment of organelle localization	GO:0051656	37	0.013
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.013
protein localization to membrane	GO:0072657	36	0.013
peptide hormone secretion	GO:0030072	84	0.013
positive regulation of phosphate metabolic process	GO:0045937	262	0.013
regulation of purine nucleotide metabolic process	GO:1900542	115	0.013
membrane organization	GO:0061024	94	0.013
negative regulation of cellular biosynthetic process	GO:0031327	161	0.013
metal ion transport	GO:0030001	289	0.013
regulation of secretion	GO:0051046	224	0.013
establishment of vesicle localization	GO:0051650	31	0.013
postnatal olfactory bulb interneuron migration	GO:0021827	1	0.013
response to ammonium ion	GO:0060359	71	0.013
positive regulation of cell proliferation	GO:0008284	249	0.012
response to extracellular stimulus	GO:0009991	380	0.012
regulation of growth	GO:0040008	105	0.012
actin filament based process	GO:0030029	86	0.012
localization of cell	GO:0051674	202	0.012
appendage morphogenesis	GO:0035107	4	0.012
regulation of homotypic cell cell adhesion	GO:0034110	4	0.012
protein tetramerization	GO:0051262	38	0.012
neural crest cell differentiation	GO:0014033	2	0.012
negative regulation of apoptotic process	GO:0043066	181	0.012
anion transmembrane transport	GO:0098656	77	0.012
cellular response to nitrogen compound	GO:1901699	210	0.012
regulation of protein metabolic process	GO:0051246	289	0.012
cyclic purine nucleotide metabolic process	GO:0052652	62	0.012
acid secretion	GO:0046717	48	0.012
startle response	GO:0001964	2	0.012
ras protein signal transduction	GO:0007265	29	0.012
positive regulation of rna metabolic process	GO:0051254	203	0.012
regulation of response to stress	GO:0080134	126	0.012
male mating behavior	GO:0060179	3	0.012
anatomical structure morphogenesis	GO:0009653	298	0.012
amide transport	GO:0042886	105	0.012
regulation of axon extension	GO:0030516	24	0.011
regulation of cell proliferation	GO:0042127	359	0.011
establishment of synaptic vesicle localization	GO:0097480	23	0.011
camp metabolic process	GO:0046058	63	0.011
cation transport	GO:0006812	382	0.011
organophosphate biosynthetic process	GO:0090407	143	0.011
regulation of cell growth	GO:0001558	85	0.011
epithelium development	GO:0060429	96	0.011
negative regulation of dopamine secretion	GO:0033602	4	0.011
signal release	GO:0023061	145	0.011
macroautophagy	GO:0016236	4	0.011
regulation of cell differentiation	GO:0045595	320	0.011
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.011
aging	GO:0007568	241	0.011
positive regulation of signaling	GO:0023056	270	0.011
transcription from rna polymerase ii promoter	GO:0006366	252	0.011
single organism catabolic process	GO:0044712	283	0.011
regulation of cell cycle	GO:0051726	73	0.011
positive regulation of cell communication	GO:0010647	271	0.011
lens fiber cell differentiation	GO:0070306	3	0.011
gamete generation	GO:0007276	124	0.010
synaptic vesicle endocytosis	GO:0048488	4	0.010
anatomical structure maturation	GO:0071695	2	0.010
respiratory system process	GO:0003016	3	0.010
eye morphogenesis	GO:0048592	4	0.010
regulation of insulin secretion	GO:0050796	65	0.010
calcium ion transmembrane transport	GO:0070588	70	0.010
response to nutrient levels	GO:0031667	370	0.010
neuronal action potential	GO:0019228	35	0.010
purine nucleoside metabolic process	GO:0042278	169	0.010
secretion	GO:0046903	307	0.010
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.010
circulatory system process	GO:0003013	183	0.010
regulation of developmental growth	GO:0048638	45	0.010
positive regulation of molecular function	GO:0044093	230	0.010
dicarboxylic acid transport	GO:0006835	34	0.010

Pcdha13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.013
disease of anatomical entity	DOID:7	0.013
disease of cellular proliferation	DOID:14566	0.011
musculoskeletal system disease	DOID:17	0.011
cancer	DOID:162	0.011
organ system cancer	DOID:0050686	0.011

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