Rattus norvegicus

108 known processes

Rnf4

ring finger protein 4

(Aliases: MGC72476)

Rnf4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell type specific apoptotic processGO:00972851340.514
regulation of protein transportGO:0051223680.457
cellular component biogenesisGO:00440853680.352
Human
single organism cellular localizationGO:19025801020.304
golgi vesicle transportGO:0048193220.291
regulation of secretionGO:00510462240.288
regulation of phosphorylationGO:00423252480.284
intracellular transportGO:00469071850.263
protein complex subunit organizationGO:00718223020.239
Human
actin myosin filament slidingGO:003327520.226
macromolecule localizationGO:00330362520.225
peristalsisGO:003043220.223
carboxylic acid metabolic processGO:00197522890.217
regulation of catalytic activityGO:00507903040.215
intracellular signal transductionGO:00355563140.208
growthGO:00400071650.207
behaviorGO:00076102050.201
release of cytochrome c from mitochondriaGO:000183680.197
positive regulation of response to stimulusGO:00485842850.195
regulation of kinase activityGO:00435491170.195
anatomical structure morphogenesisGO:00096532980.192
protein transportGO:00150311320.171
apoptotic processGO:00069153810.168
protein localizationGO:00081041910.164
positive regulation of signalingGO:00230562700.163
cognitionGO:0050890920.163
g protein coupled receptor signaling pathwayGO:00071862420.152
single organism intracellular transportGO:19025821660.151
mapk cascadeGO:00001651400.150
cellular protein localizationGO:00346131220.149
regulation of cellular localizationGO:00603412630.149
cellular component movementGO:00069282480.145
programmed cell deathGO:00125013920.144
secretionGO:00469033070.144
regulation of protein metabolic processGO:00512462890.143
organic acid metabolic processGO:00060822920.143
neuron developmentGO:00486662860.142
cellular response to stressGO:00335542690.136
positive regulation of signal transductionGO:00099671750.132
rhythmic behaviorGO:0007622240.129
macromolecular complex subunit organizationGO:00439333390.128
Human
cell cell signalingGO:00072673350.127
regulation of secretion by cellGO:19035302080.125
regulation of cellular component organizationGO:00511283680.124
Human
positive regulation of cell communicationGO:00106472710.119
protein complex assemblyGO:00064612630.119
Human
negative regulation of cellular metabolic processGO:00313242810.115
atp metabolic processGO:0046034720.113
signal transduction by phosphorylationGO:00230141440.113
regulation of intracellular signal transductionGO:19025312180.113
locomotionGO:00400112370.112
positive regulation of cell proliferationGO:00082842490.111
establishment of protein localizationGO:00451841410.110
positive regulation of phosphorus metabolic processGO:00105622620.109
ribonucleoprotein complex biogenesisGO:0022613100.108
activation of mapkkk activityGO:000018510.107
cellular macromolecule localizationGO:00707271220.106
macromolecular complex assemblyGO:00650032730.106
Human
regulation of cell cycleGO:0051726730.103
Human
response to inorganic substanceGO:00100353770.103
protein phosphorylationGO:00064683450.103
positive regulation of cell motilityGO:2000147970.102
positive regulation of macromolecule biosynthetic processGO:00105572470.101
regulation of apoptotic processGO:00429813350.098
cellular catabolic processGO:00442482950.097
Human
regulation of programmed cell deathGO:00430673410.096
neurological system processGO:00508772190.096
positive regulation of biosynthetic processGO:00098913190.096
positive regulation of phosphate metabolic processGO:00459372620.096
regulation of cell motilityGO:20001451310.096
reproductive processGO:00224143720.095
regulation of protein modification processGO:00313991940.093
positive regulation of protein metabolic processGO:00512471780.093
organic substance catabolic processGO:19015753160.092
Human
nucleobase containing small molecule metabolic processGO:00550863160.091
neuron apoptotic processGO:0051402880.091
regulation of establishment of protein localizationGO:0070201690.091
embryonic pattern specificationGO:000988010.089
protein complex biogenesisGO:00702712630.088
Human
positive regulation of cell deathGO:00109421840.085
single organism organelle organizationGO:19025891800.084
Human
regulation of neuron apoptotic processGO:0043523830.084
circadian sleep wake cycleGO:0042745230.083
monocarboxylic acid metabolic processGO:00327871520.083
positive regulation of protein transportGO:0051222410.083
regulation of molecular functionGO:00650093980.082
regulation of protein phosphorylationGO:00019321830.081
signal releaseGO:00230611450.081
anterior posterior pattern specificationGO:000995210.076
immune system processGO:00023762040.073
ribonucleoside triphosphate catabolic processGO:00092031220.073
regulation of cellular protein metabolic processGO:00322682670.072
regulation of protein kinase activityGO:00458591050.072
positive regulation of programmed cell deathGO:00430681570.072
secretion by cellGO:00329402480.072
regulation of phosphorus metabolic processGO:00511743490.071
response to alkaloidGO:00432791320.070
positive regulation of neuron apoptotic processGO:0043525330.069
cellular amino acid metabolic processGO:00065201070.068
regulation of hydrolase activityGO:00513361430.067
circadian sleep wake cycle sleepGO:0050802210.066
positive regulation of phosphorylationGO:00423271770.066
sexual reproductionGO:00199531480.065
positive regulation of transportGO:00510502450.065
positive regulation of neuron deathGO:1901216430.065
positive regulation of nitrogen compound metabolic processGO:00511733340.063
small gtpase mediated signal transductionGO:0007264360.063
regulation of microtubule polymerizationGO:003111380.062
positive regulation of small gtpase mediated signal transductionGO:005105790.062
jak stat cascadeGO:0007259260.061
transcription dna templatedGO:00063513770.061
synaptic growth at neuromuscular junctionGO:005112410.060
positive regulation of molecular functionGO:00440932300.059
catabolic processGO:00090563510.058
Human
cellular component assemblyGO:00226073600.057
Human
single organism behaviorGO:00447081300.057
neuron deathGO:00709971270.057
positive regulation of actin filament polymerizationGO:003083850.057
oxoacid metabolic processGO:00434362900.055
regulation of behaviorGO:0050795610.055
positive regulation of cellular biosynthetic processGO:00313282950.054
positive regulation of catalytic activityGO:00430851840.054
response to extracellular stimulusGO:00099913800.054
regulation of hormone levelsGO:00108171870.053
reproductionGO:00000032450.053
single organism reproductive processGO:00447022970.053
response to interleukin 13GO:003596230.052
positive regulation of nucleobase containing compound metabolic processGO:00459353190.052
positive regulation of dendritic spine morphogenesisGO:006100330.051
positive regulation of transcription dna templatedGO:00458931970.051
regulation of nervous system developmentGO:00519602640.051
regulation of cell migrationGO:00303341280.051
rna biosynthetic processGO:00327743800.050
positive regulation of cellular protein metabolic processGO:00322701670.050
regulation of lymphocyte migrationGO:200040110.050
chromosome segregationGO:000705920.049
positive regulation of hydrolase activityGO:0051345860.049
tissue developmentGO:00098882520.048
negative regulation of apoptotic processGO:00430661810.048
organophosphate metabolic processGO:00196373700.047
adult locomotory behaviorGO:000834440.047
rna metabolic processGO:00160704060.047
positive regulation of protein modification processGO:00314011420.047
vesicle fusion with golgi apparatusGO:004828040.046
regulation of cell proliferationGO:00421273590.045
cellular component morphogenesisGO:00329891550.045
regulation of multicellular organismal developmentGO:20000263760.045
positive regulation of apoptotic processGO:00430651540.044
cytoplasmic transportGO:00164821150.044
positive regulation of secretionGO:00510471400.044
carbohydrate derivative metabolic processGO:19011353460.043
regulation of signal transductionGO:00099663180.043
cellular response to endogenous stimulusGO:00714953770.042
mitotic spindle organizationGO:000705220.042
regulation of protein secretionGO:0050708280.042
positive regulation of intracellular signal transductionGO:19025331380.042
negative regulation of metabolic processGO:00098923310.041
synaptic transmissionGO:00072682350.041
organelle assemblyGO:0070925220.040
Human
olfactory learningGO:000835510.040
vesicle mediated transportGO:00161921810.040
metal ion transportGO:00300012890.040
proteolysisGO:00065081750.039
Human
regulation of transferase activityGO:00513381230.039
response to cocaineGO:0042220390.039
positive regulation of cell migrationGO:0030335960.039
organ morphogenesisGO:0009887750.039
negative regulation of programmed cell deathGO:00430691830.039
sensory perceptionGO:00076001010.038
developmental process involved in reproductionGO:00030061590.038
exit from mitosisGO:001045810.038
axis specificationGO:000979840.038
localization of cellGO:00516742020.038
cation homeostasisGO:00550801950.038
learning or memoryGO:0007611900.038
wound healingGO:00420601220.037
nucleoside metabolic processGO:00091161790.037
protein oligomerizationGO:00512591910.036
response to biotic stimulusGO:00096072260.036
protein targetingGO:0006605610.035
regulation of leukocyte migrationGO:0002685240.035
positive regulation of protein phosphorylationGO:00019341350.034
membrane organizationGO:0061024940.034
multi organism reproductive processGO:00447032620.034
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.034
ras protein signal transductionGO:0007265290.034
protein maturationGO:0051604680.034
regulation of nucleic acid templated transcriptionGO:19035063800.033
meiotic cell cycle processGO:190304630.033
macroautophagyGO:001623640.033
negative regulation of cell deathGO:00605482290.032
cellular response to nutrient levelsGO:0031669600.031
regulation of interleukin 1 beta secretionGO:005070630.031
purine ribonucleotide metabolic processGO:00091502270.031
positive regulation of mapk cascadeGO:0043410920.031
positive regulation of secretion by cellGO:19035321280.030
regulation of lymphocyte chemotaxisGO:190162310.030
regulation of cellular component biogenesisGO:0044087860.030
Human
brain developmentGO:00074202470.030
negative regulation of signalingGO:00230571570.030
nuclear transportGO:0051169490.030
organelle organizationGO:00069962660.030
Human
positive regulation of cellular amino acid metabolic processGO:004576410.029
positive regulation of protein polymerizationGO:0032273100.029
ribose phosphate metabolic processGO:00196932350.029
cytoskeleton organizationGO:00070101110.029
Human
cell projection organizationGO:00300303020.029
multicellular organismal reproductive processGO:00486092330.029
nucleoside triphosphate catabolic processGO:00091431230.029
regulation of circadian sleep wake cycleGO:0042749180.029
regulation of cellular component movementGO:00512701500.028
small molecule biosynthetic processGO:00442831240.028
response to other organismGO:00517072200.028
rhythmic processGO:00485111560.028
cell motilityGO:00488702020.028
circadian rhythmGO:0007623880.028
cellular response to external stimulusGO:00714961180.028
lipid metabolic processGO:00066292830.028
defense responseGO:00069521940.028
regulation of protein serine threonine kinase activityGO:0071900640.028
circulatory system developmentGO:00723591340.027
embryonic axis specificationGO:000057810.027
regulation of cellular ketone metabolic processGO:0010565270.027
regulation of neuron differentiationGO:00456642080.027
leukocyte chemotaxisGO:0030595220.027
cell projection morphogenesisGO:00488581230.027
regulation of cell developmentGO:00602842630.027
protein localization to organelleGO:0033365570.027
regulation of circadian sleep wake cycle sleepGO:0045187180.026
response to toxic substanceGO:00096361330.026
triglyceride homeostasisGO:007032820.026
developmental growthGO:00485891000.026
lipid localizationGO:0010876620.026
carboxylic acid biosynthetic processGO:0046394830.025
regulation of dendritic spine morphogenesisGO:006100160.025
response to external biotic stimulusGO:00432072210.025
dna metabolic processGO:0006259960.025
response to oxidative stressGO:00069791860.025
gamete generationGO:00072761240.025
single organism catabolic processGO:00447122830.025
enzyme linked receptor protein signaling pathwayGO:00071671160.024
positive regulation of cellular component movementGO:00512721020.024
glial cell proliferationGO:0014009170.024
regulation of rna biosynthetic processGO:20011413810.024
neuron differentiationGO:00301823680.024
tube developmentGO:0035295890.024
protein processingGO:0016485680.024
response to temperature stimulusGO:0009266940.024
neuron projection developmentGO:00311752730.024
regulation of system processGO:00440572080.024
regulation of cellular amino acid metabolic processGO:000652120.024
regulation of neuron deathGO:19012141150.023
amine metabolic processGO:0009308380.023
arp2 3 complex mediated actin nucleationGO:003431420.023
cellular ion homeostasisGO:00068731840.023
regulation of smoothened signaling pathwayGO:000858920.023
homeostatic processGO:00425923310.023
embryo developmentGO:0009790490.022
nucleobase containing compound catabolic processGO:00346551520.022
response to nutrient levelsGO:00316673700.022
regulation of dendrite developmentGO:0050773590.022
cellular amine metabolic processGO:0044106380.022
cell cycleGO:00070491010.022
Human
phenol containing compound metabolic processGO:0018958300.022
positive regulation of catabolic processGO:0009896780.022
purine ribonucleoside triphosphate metabolic processGO:00092051400.022
regulation of nucleotide metabolic processGO:00061401170.022
protein homooligomerizationGO:0051260910.022
microtubule cytoskeleton organizationGO:0000226250.022
Human
purine nucleotide metabolic processGO:00061632290.022
response to osmotic stressGO:0006970420.021
heterocycle catabolic processGO:00467001670.021
regulation of mapk cascadeGO:00434081160.021
potassium ion transportGO:0006813970.021
muscle system processGO:00030121150.021
innate immune responseGO:0045087350.021
positive regulation of interleukin 1 secretionGO:005071630.021
peptidyl amino acid modificationGO:00181931260.021
cell morphogenesisGO:00009021420.021
circadian behaviorGO:0048512240.021
cellular ketone metabolic processGO:0042180510.021
protein import into nucleusGO:0006606350.021
nucleoside monophosphate metabolic processGO:0009123930.020
nucleoside catabolic processGO:00091641260.020
nucleoside phosphate metabolic processGO:00067532830.020
head developmentGO:00603222470.020
carbohydrate derivative catabolic processGO:19011361470.020
regulation of cell differentiationGO:00455953200.020
organonitrogen compound catabolic processGO:19015651790.020
actin filament cappingGO:005169320.020
purine ribonucleoside metabolic processGO:00461281680.020
negative regulation of cell communicationGO:00106481580.020
regulation of protein complex assemblyGO:0043254330.020
Human
regulation of phosphate metabolic processGO:00192203490.019
multicellular organism growthGO:003526410.019
response to oxygen levelsGO:00704822650.019
positive regulation of apoptotic signaling pathwayGO:200123560.019
positive regulation of gene expressionGO:00106282440.019
regulation of meiotic cell cycleGO:005144530.019
cellular response to abiotic stimulusGO:0071214850.019
positive regulation of developmental processGO:00510942830.019
protein geranylgeranylationGO:001834440.019
positive regulation of cell differentiationGO:00455972170.019
heart morphogenesisGO:000300730.019
ncrna processingGO:003447030.019
response to nicotineGO:0035094510.018
multicellular organism reproductionGO:00325042330.018
dendrite morphogenesisGO:0048813430.018
cell growthGO:00160491040.018
response to metal ionGO:00100382530.018
response to bacteriumGO:00096172000.018
actin filament based processGO:0030029860.017
regulation of protein localizationGO:0032880810.017
feeding behaviorGO:0007631530.017
positive regulation of dna metabolic processGO:0051054390.017
neuron projection morphogenesisGO:00488121220.017
cellular nitrogen compound catabolic processGO:00442701630.017
cellular response to peptideGO:19016531330.017
regulation of cell morphogenesisGO:0022604770.017
spindle organizationGO:000705120.017
Human
regulation of protein polymerizationGO:0032271190.017
regulation of anatomical structure sizeGO:00900661350.017
nucleoside monophosphate catabolic processGO:0009125560.017
regulation of hormone secretionGO:00468831060.017
blood circulationGO:00080151830.017
positive regulation of protein acetylationGO:190198530.017
response to cytokineGO:00340972150.016
glycosyl compound catabolic processGO:19016581260.016
cellular cation homeostasisGO:00300031800.016
rna localizationGO:000640340.016
organophosphate catabolic processGO:00464341480.016
response to hydrogen peroxideGO:0042542890.016
cellular response to extracellular stimulusGO:0031668730.015
single organism biosynthetic processGO:00447113420.015
negative regulation of protein metabolic processGO:00512481140.015
regulation of actin nucleationGO:005112520.015
activation of protein kinase activityGO:0032147470.015
regulation of synaptic transmissionGO:00508041410.015
apoptotic mitochondrial changesGO:0008637100.015
positive regulation of release of cytochrome c from mitochondriaGO:009020030.015
nucleotide metabolic processGO:00091172790.015
positive regulation of cellular component biogenesisGO:0044089550.015
positive regulation of erk1 and erk2 cascadeGO:0070374290.015
agingGO:00075682410.015
nucleic acid templated transcriptionGO:00976593790.015
memoryGO:0007613540.015
mast cell migrationGO:009753140.015
negative regulation of macromolecule metabolic processGO:00106052600.015
nucleotide catabolic processGO:00091661390.014
organic cyclic compound catabolic processGO:19013611750.014
regulation of peptidase activityGO:0052547550.014
positive regulation of kinase activityGO:0033674770.014
hemidesmosome assemblyGO:003158110.014
positive regulation of cellular component organizationGO:00511302000.014
response to ammonium ionGO:0060359710.014
reproductive structure developmentGO:00486081280.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
regulation of muscle cell apoptotic processGO:0010660260.014
protein secretionGO:0009306340.014
regulation of microtubule polymerization or depolymerizationGO:0031110120.014
smooth muscle cell proliferationGO:0048659770.014
peptidyl tyrosine phosphorylationGO:0018108720.014
positive regulation of smooth muscle cell proliferationGO:0048661510.014
cellular lipid metabolic processGO:00442552080.014
regulation of protein stabilityGO:003164760.014
olfactory behaviorGO:004204820.014
positive regulation of intracellular transportGO:0032388390.014
cell migrationGO:00164771970.014
negative regulation of molecular functionGO:00440921330.014
modification dependent protein catabolic processGO:0019941140.014
Human
positive regulation of mitochondrion organizationGO:001082240.014
dendrite developmentGO:0016358720.013
mitotic cell cycleGO:0000278490.013
reactive oxygen species biosynthetic processGO:190340980.013
cellular response to organic cyclic compoundGO:00714072020.013
positive regulation of protein secretionGO:0050714190.013
ion homeostasisGO:00508012120.013
regulation of cytoskeleton organizationGO:0051493490.013
Human
immune effector processGO:0002252530.013
aromatic compound catabolic processGO:00194391680.013
regulation of endopeptidase activityGO:0052548510.013
peptidyl tyrosine modificationGO:0018212720.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
regulation of intracellular transportGO:0032386650.013
cell part morphogenesisGO:00329901230.013
ribonucleotide metabolic processGO:00092592310.013
anatomical structure formation involved in morphogenesisGO:0048646830.012
tube formationGO:003514830.012
regulation of protein maturationGO:1903317500.012
rna processingGO:0006396220.012
myeloid leukocyte activationGO:0002274360.012
vesicle organizationGO:0016050290.012
cellular response to growth factor stimulusGO:00713631620.012
lipid transportGO:0006869610.012
purine nucleoside monophosphate metabolic processGO:0009126840.012
regulation of chemotaxisGO:0050920290.012
maintenance of locationGO:0051235170.012
protein polymerizationGO:0051258220.012
response to reactive oxygen speciesGO:00003021200.012
muscle structure developmentGO:0061061870.012
mitotic cell cycle processGO:1903047350.012
regulation of protein processingGO:0070613500.012
cardiovascular system developmentGO:00723581340.012
establishment of protein localization to organelleGO:0072594440.012
ribonucleoside catabolic processGO:00424541260.012
atp catabolic processGO:0006200540.012
transmembrane transportGO:00550854120.012
lipid storageGO:001991510.012
positive regulation of rna biosynthetic processGO:19026801970.012
regulation of dna metabolic processGO:0051052600.012
carbohydrate derivative biosynthetic processGO:19011371240.012
regulation of locomotionGO:00400121480.012
positive regulation of response to external stimulusGO:0032103510.012
regulation of actin filament based processGO:0032970420.012
ribonucleoside monophosphate catabolic processGO:0009158550.012
regulation of canonical wnt signaling pathwayGO:006082840.012
syncytium formationGO:000694940.012
cellular homeostasisGO:00197252520.012
myoblast fusionGO:000752020.012
positive regulation of cell developmentGO:00107201760.011
cellular response to oxygen containing compoundGO:19017013860.011
regulation of protein oligomerizationGO:003245920.011
secondary metabolic processGO:0019748150.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126910.011
cell cycle checkpointGO:000007520.011
positive regulation of cytoskeleton organizationGO:0051495260.011
necroptotic processGO:007026620.011
erbb signaling pathwayGO:0038127230.011
syncytium formation by plasma membrane fusionGO:000076830.011
establishment of organelle localizationGO:0051656370.011
negative regulation of dopamine secretionGO:003360240.011
protein targeting to nucleusGO:0044744350.011
cytosolic calcium ion homeostasisGO:00514801400.011
positive regulation of camp metabolic processGO:0030816310.011
heart developmentGO:0007507720.011
negative regulation of cellular protein metabolic processGO:00322691060.011
cation transportGO:00068123820.011
hormone metabolic processGO:0042445690.011
regulation of membrane potentialGO:00423911100.011
cofactor metabolic processGO:0051186950.011
positive regulation of rna metabolic processGO:00512542030.011
positive regulation of transferase activityGO:0051347810.011
cell morphogenesis involved in differentiationGO:00009041190.011
positive regulation of immune system processGO:0002684900.010
regulation of rna metabolic processGO:00512523910.010
purine containing compound metabolic processGO:00725212530.010
cellular metal ion homeostasisGO:00068751720.010
negative regulation of neuron apoptotic processGO:0043524450.010
eye morphogenesisGO:004859240.010
sex differentiationGO:00075481130.010
positive regulation of protein kinase activityGO:0045860730.010
regulation of retinal cell programmed cell deathGO:004666810.010
purine nucleotide catabolic processGO:00061951360.010
positive regulation of intracellular protein transportGO:0090316200.010

Rnf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
colon cancerDOID:21900.028
intestinal cancerDOID:1015500.028
gastrointestinal system cancerDOID:311900.028
colorectal cancerDOID:925600.028
organ system cancerDOID:005068600.028
disease of cellular proliferationDOID:1456600.028
cancerDOID:16200.028
large intestine cancerDOID:567200.028
colon carcinomaDOID:152000.028
chromosomal diseaseDOID:008001400.012