Rattus norvegicus

13 known processes

Igsf1

immunoglobulin superfamily, member 1

(Aliases: Inhbp,MGC156568)

Igsf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.249
metal ion homeostasisGO:00550651860.195
cellular calcium ion homeostasisGO:00068741600.170
cation transportGO:00068123820.164
cellular response to endogenous stimulusGO:00714953770.159
oxoacid metabolic processGO:00434362900.155
cellular response to organonitrogen compoundGO:00714171970.154
cytosolic calcium ion homeostasisGO:00514801400.154
nitrogen compound transportGO:00717052290.148
organic acid transportGO:00158491160.138
organic acid metabolic processGO:00060822920.129
cellular cation homeostasisGO:00300031800.124
positive regulation of nitrogen compound metabolic processGO:00511733340.123
cation homeostasisGO:00550801950.122
positive regulation of cell differentiationGO:00455972170.120
cellular divalent inorganic cation homeostasisGO:00725031620.117
carboxylic acid transportGO:00469421150.112
reproductive processGO:00224143720.111
regulation of cell developmentGO:00602842630.103
single organism biosynthetic processGO:00447113420.102
tissue developmentGO:00098882520.098
cellular amino acid metabolic processGO:00065201070.098
neuron differentiationGO:00301823680.097
calcium ion homeostasisGO:00550741620.097
positive regulation of cellular biosynthetic processGO:00313282950.097
cellular response to hormone stimulusGO:00328702470.095
cellular chemical homeostasisGO:00550822470.094
rna metabolic processGO:00160704060.094
Human
regulation of apoptotic processGO:00429813350.092
positive regulation of biosynthetic processGO:00098913190.086
divalent inorganic cation homeostasisGO:00725071650.084
ion homeostasisGO:00508012120.083
locomotionGO:00400112370.083
cellular ion homeostasisGO:00068731840.083
ion transmembrane transportGO:00342203650.073
transmembrane transportGO:00550854120.071
divalent inorganic cation transportGO:00725111340.071
nucleic acid templated transcriptionGO:00976593790.069
Human
single organism carbohydrate metabolic processGO:00447231180.069
regulation of secretionGO:00510462240.068
negative regulation of cell deathGO:00605482290.068
negative regulation of apoptotic processGO:00430661810.067
carbohydrate biosynthetic processGO:0016051420.067
multicellular organism reproductionGO:00325042330.067
positive regulation of cell proliferationGO:00082842490.066
central nervous system developmentGO:00074173110.065
cellular modified amino acid metabolic processGO:0006575610.064
cellular homeostasisGO:00197252520.063
regulation of phosphorus metabolic processGO:00511743490.063
response to campGO:0051591910.062
multi organism reproductive processGO:00447032620.060
chemical homeostasisGO:00488782920.058
regulation of calcium ion transportGO:0051924770.057
response to purine containing compoundGO:00140741260.055
single organism reproductive processGO:00447022970.055
organonitrogen compound biosynthetic processGO:19015661670.054
intracellular signal transductionGO:00355563140.052
hormone transportGO:00099141210.052
neurotrophin productionGO:003289820.052
hormone secretionGO:00468791150.050
negative regulation of metabolic processGO:00098923310.050
nucleobase containing small molecule metabolic processGO:00550863160.050
regulation of secretion by cellGO:19035302080.050
amine metabolic processGO:0009308380.049
positive regulation of nucleobase containing compound metabolic processGO:00459353190.049
positive regulation of phosphorus metabolic processGO:00105622620.047
neuron projection developmentGO:00311752730.047
behaviorGO:00076102050.047
regulation of rna biosynthetic processGO:20011413810.047
Human
carbohydrate derivative metabolic processGO:19011353460.046
regulation of cell proliferationGO:00421273590.046
neuron developmentGO:00486662860.046
response to oxygen levelsGO:00704822650.046
cellular response to nitrogen compoundGO:19016992100.045
response to organophosphorusGO:00466831020.045
response to ketoneGO:19016541820.045
organophosphate metabolic processGO:00196373700.045
feeding behaviorGO:0007631530.044
renal system processGO:0003014400.044
carbohydrate metabolic processGO:00059751300.044
response to peptideGO:19016522920.044
negative regulation of cellular metabolic processGO:00313242810.043
negative regulation of cellular biosynthetic processGO:00313271610.043
rna biosynthetic processGO:00327743800.043
Human
regulation of cellular localizationGO:00603412630.042
positive regulation of intracellular signal transductionGO:19025331380.042
negative regulation of nitrogen compound metabolic processGO:00511721610.042
homeostatic processGO:00425923310.042
positive regulation of macromolecule biosynthetic processGO:00105572470.042
anatomical structure morphogenesisGO:00096532980.042
peptidyl amino acid modificationGO:00181931260.042
positive regulation of phosphate metabolic processGO:00459372620.041
regulation of rna metabolic processGO:00512523910.041
Human
positive regulation of cytosolic calcium ion concentrationGO:00072041220.039
cellular component movementGO:00069282480.039
cellular amine metabolic processGO:0044106380.038
anion transportGO:00068201780.038
organic anion transportGO:00157111320.038
regulation of cellular amino acid metabolic processGO:000652120.037
cellular metal ion homeostasisGO:00068751720.037
positive regulation of protein metabolic processGO:00512471780.037
carbohydrate derivative biosynthetic processGO:19011371240.036
regulation of nucleic acid templated transcriptionGO:19035063800.036
Human
agingGO:00075682410.036
single organism catabolic processGO:00447122830.036
response to temperature stimulusGO:0009266940.036
transcription dna templatedGO:00063513770.036
Human
divalent metal ion transportGO:00708381320.036
regulation of programmed cell deathGO:00430673410.036
positive regulation of protein modification processGO:00314011420.035
response to extracellular stimulusGO:00099913800.035
head developmentGO:00603222470.035
response to acid chemicalGO:00011012220.035
response to hypoxiaGO:00016662310.035
intestinal absorptionGO:005089230.034
reproductionGO:00000032450.034
cellular ketone metabolic processGO:0042180510.034
positive regulation of calcium ion transportGO:0051928360.034
organic hydroxy compound metabolic processGO:19016151150.034
forebrain developmentGO:0030900980.034
cellular response to external stimulusGO:00714961180.034
regulation of blood vessel sizeGO:0050880890.034
cellular response to growth factor stimulusGO:00713631620.033
cellular response to oxygen containing compoundGO:19017013860.033
single organism intracellular transportGO:19025821660.033
purine containing compound metabolic processGO:00725212530.033
regulation of hormone secretionGO:00468831060.032
positive regulation of nucleic acid templated transcriptionGO:19035081970.032
regulation of metal ion transportGO:00109591180.032
regulation of phosphate metabolic processGO:00192203490.032
purine ribonucleotide metabolic processGO:00091502270.032
regulation of cell differentiationGO:00455953200.032
response to ethanolGO:00454711620.032
biological adhesionGO:00226101100.031
regulation of transcription from rna polymerase ii promoterGO:00063572340.030
regulation of cellular ketone metabolic processGO:0010565270.030
female pregnancyGO:00075651220.030
inflammatory responseGO:00069541500.030
regulation of molecular functionGO:00650093980.030
eye morphogenesisGO:004859240.030
negative regulation of programmed cell deathGO:00430691830.030
reproductive structure developmentGO:00486081280.029
calcium ion transportGO:00068161310.029
cell morphogenesis involved in differentiationGO:00009041190.029
cell cycleGO:00070491010.029
regulation of protein phosphorylationGO:00019321830.029
regulation of cellular amine metabolic processGO:003323880.029
cell cell signalingGO:00072673350.029
negative regulation of multicellular organismal processGO:00512412030.029
circadian rhythmGO:0007623880.028
response to nutrientGO:00075842480.028
negative regulation of macromolecule biosynthetic processGO:00105581480.028
glial cell differentiationGO:0010001650.028
programmed cell deathGO:00125013920.028
positive regulation of transcription dna templatedGO:00458931970.028
protein complex biogenesisGO:00702712630.028
nucleoside phosphate metabolic processGO:00067532830.028
response to ammonium ionGO:0060359710.027
tube developmentGO:0035295890.027
multicellular organismal reproductive processGO:00486092330.027
intracellular transportGO:00469071850.027
positive regulation of rna biosynthetic processGO:19026801970.027
rhythmic processGO:00485111560.027
neuron neuron synaptic transmissionGO:0007270600.027
calcium ion transmembrane transportGO:0070588700.027
negative regulation of phosphate metabolic processGO:0045936800.027
transcription from rna polymerase ii promoterGO:00063662520.027
cognitionGO:0050890920.027
neurological system processGO:00508772190.026
organophosphate biosynthetic processGO:00904071430.026
regulation of transcription dna templatedGO:00063553740.026
Human
positive regulation of rna metabolic processGO:00512542030.026
nicotinamide nucleotide metabolic processGO:0046496280.026
response to cytokineGO:00340972150.026
response to peptide hormoneGO:00434342780.026
cell morphogenesisGO:00009021420.025
response to woundingGO:00096112540.025
response to monosaccharideGO:00342841590.025
cell projection organizationGO:00300303020.025
positive regulation of transportGO:00510502450.025
sequestering of calcium ionGO:005120880.025
positive regulation of secretionGO:00510471400.025
amino acid transportGO:0006865700.025
regulation of cellular protein metabolic processGO:00322682670.025
negative regulation of gene expressionGO:00106291990.024
regulation of neurogenesisGO:00507672470.024
response to alkaloidGO:00432791320.024
protein tetramerizationGO:0051262380.024
regulation of body fluid levelsGO:0050878900.024
organic hydroxy compound transportGO:0015850770.024
protein complex subunit organizationGO:00718223020.024
regulation of anatomical structure morphogenesisGO:00226031410.023
regulation of protein metabolic processGO:00512462890.023
regulation of system processGO:00440572080.023
regulation of anion transportGO:0044070430.023
dicarboxylic acid transportGO:0006835340.023
peptidyl tyrosine phosphorylationGO:0018108720.023
phenol containing compound metabolic processGO:0018958300.023
protein complex assemblyGO:00064612630.022
cellular carbohydrate metabolic processGO:0044262720.022
regulation of excretionGO:0044062210.022
regulation of protein modification processGO:00313991940.022
development of primary sexual characteristicsGO:00451371070.022
pancreatic a cell differentiationGO:000331010.022
amine transportGO:0015837570.022
positive regulation of molecular functionGO:00440932300.022
response to transition metal nanoparticleGO:19902671220.022
skeletal muscle tissue developmentGO:0007519310.022
positive regulation of lipid biosynthetic processGO:0046889250.022
non canonical wnt signaling pathwayGO:003556730.022
response to decreased oxygen levelsGO:00362932370.022
secretionGO:00469033070.022
positive regulation of cellular protein metabolic processGO:00322701670.022
regulation of cellular component movementGO:00512701500.022
protein kinase c activating g protein coupled receptor signaling pathwayGO:0007205120.022
inner ear morphogenesisGO:004247210.022
cell motilityGO:00488702020.022
response to glucocorticoidGO:00513842230.022
multicellular organism growthGO:003526410.021
sensory organ developmentGO:0007423740.021
regulation of neuron deathGO:19012141150.021
neural crest cell differentiationGO:001403320.021
positive regulation of catalytic activityGO:00430851840.021
amide transportGO:00428861050.021
macromolecular complex subunit organizationGO:00439333390.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
gland developmentGO:00487321550.021
sequestering of metal ionGO:005123890.021
endocrine processGO:0050886320.020
synaptic transmissionGO:00072682350.020
axis specificationGO:000979840.020
response to metal ionGO:00100382530.020
regulation of neuron differentiationGO:00456642080.020
oxidation reduction processGO:00551143040.020
purine ribonucleotide biosynthetic processGO:0009152810.020
circulatory system processGO:00030131830.020
regulation of hormone levelsGO:00108171870.020
response to toxic substanceGO:00096361330.020
positive regulation of neurogenesisGO:00507691650.020
cellular glucan metabolic processGO:0006073230.020
secretion by cellGO:00329402480.020
cation transmembrane transportGO:00986552630.020
positive regulation of gene expressionGO:00106282440.020
positive regulation of cellular amine metabolic processGO:003324030.019
muscle structure developmentGO:0061061870.019
peptide transportGO:0015833970.019
purine nucleotide metabolic processGO:00061632290.019
positive regulation of protein kinase activityGO:0045860730.019
neuron deathGO:00709971270.019
multi multicellular organism processGO:00447061380.019
regulation of protein kinase activityGO:00458591050.019
neural crest cell migrationGO:000175510.019
regenerationGO:00310991630.019
regulation of intracellular signal transductionGO:19025312180.019
negative regulation of nervous system developmentGO:0051961790.019
nucleotide biosynthetic processGO:0009165980.019
positive regulation of secretion by cellGO:19035321280.019
hexose metabolic processGO:0019318580.019
nucleoside catabolic processGO:00091641260.019
defense responseGO:00069521940.019
maintenance of locationGO:0051235170.019
embryo implantationGO:0007566150.019
cellular component morphogenesisGO:00329891550.018
muscle tissue developmentGO:0060537580.018
glucose homeostasisGO:0042593750.018
cellular response to peptide hormone stimulusGO:00713751200.018
positive regulation of phosphorylationGO:00423271770.018
response to carbohydrateGO:00097431830.018
organic substance catabolic processGO:19015753160.018
positive regulation of developmental processGO:00510942830.018
cellular response to stressGO:00335542690.018
positive regulation of signal transductionGO:00099671750.018
nucleoside phosphate biosynthetic processGO:19012931020.018
regulation of nervous system developmentGO:00519602640.018
cellular polysaccharide metabolic processGO:0044264230.018
cellular amino acid biosynthetic processGO:0008652320.018
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
response to nutrient levelsGO:00316673700.017
immune effector processGO:0002252530.017
synaptic transmission gabaergicGO:0051932220.017
ribose phosphate metabolic processGO:00196932350.017
nucleotide metabolic processGO:00091172790.017
enzyme linked receptor protein signaling pathwayGO:00071671160.017
neural crest cell developmentGO:001403220.017
negative regulation of signalingGO:00230571570.017
melanocyte differentiationGO:003031820.017
learning or memoryGO:0007611900.017
regulation of respiratory gaseous exchangeGO:004357620.017
gamete generationGO:00072761240.017
steroid biosynthetic processGO:0006694480.017
monosaccharide metabolic processGO:0005996610.017
catecholamine transportGO:0051937370.017
signal releaseGO:00230611450.017
lipid transportGO:0006869610.017
endocrine hormone secretionGO:0060986210.017
peptide secretionGO:0002790860.017
axon developmentGO:0061564960.017
purine nucleotide biosynthetic processGO:0006164830.017
g protein coupled receptor signaling pathwayGO:00071862420.016
cytosolic calcium ion transportGO:0060401390.016
single organism carbohydrate catabolic processGO:0044724400.016
developmental process involved in reproductionGO:00030061590.016
negative regulation of follicle stimulating hormone secretionGO:004688230.016
negative regulation of response to stimulusGO:00485851550.016
anterior posterior pattern specificationGO:000995210.016
positive regulation of mapk cascadeGO:0043410920.016
regulation of locomotionGO:00400121480.016
regulation of cyclic nucleotide biosynthetic processGO:0030802450.016
negative regulation of cell proliferationGO:00082851190.016
anion transmembrane transportGO:0098656770.016
regulation of ion homeostasisGO:2000021630.016
alpha amino acid metabolic processGO:1901605710.016
organelle organizationGO:00069962660.016
cellular response to tumor necrosis factorGO:0071356460.016
neuron projection morphogenesisGO:00488121220.016
organ morphogenesisGO:0009887750.016
cellular response to peptideGO:19016531330.016
cardiovascular system developmentGO:00723581340.016
response to insulinGO:00328681330.016
catecholamine biosynthetic processGO:004242390.016
protein phosphorylationGO:00064683450.016
negative regulation of biosynthetic processGO:00098901680.015
lipid metabolic processGO:00066292830.015
positive regulation of peptide secretionGO:0002793520.015
circulatory system developmentGO:00723591340.015
response to growth factorGO:00708481890.015
ribose phosphate biosynthetic processGO:0046390870.015
response to estrogenGO:00436272320.015
regulation of synaptic transmissionGO:00508041410.015
response to inorganic substanceGO:00100353770.015
positive regulation of hormone secretionGO:0046887650.015
regulation of phosphorylationGO:00423252480.015
regulation of catalytic activityGO:00507903040.015
response to molecule of bacterial originGO:00022371940.015
catabolic processGO:00090563510.015
ras protein signal transductionGO:0007265290.015
release of sequestered calcium ion into cytosolGO:0051209250.015
positive regulation of protein phosphorylationGO:00019341350.015
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.015
response to mechanical stimulusGO:00096121340.015
acute inflammatory responseGO:0002526580.015
regulation of behaviorGO:0050795610.015
hair cell differentiationGO:003531520.015
regulation of homotypic cell cell adhesionGO:003411040.014
negative regulation of macromolecule metabolic processGO:00106052600.014
regulation of signal transductionGO:00099663180.014
peptidyl tyrosine modificationGO:0018212720.014
glycosyl compound catabolic processGO:19016581260.014
spermatogenesisGO:0007283990.014
blood circulationGO:00080151830.014
regulation of homeostatic processGO:00328441010.014
carbohydrate catabolic processGO:0016052400.014
carboxylic acid biosynthetic processGO:0046394830.014
male gamete generationGO:0048232990.014
regulation of peptide hormone secretionGO:0090276800.014
positive regulation of neuron migrationGO:200122420.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
negative regulation of hormone secretionGO:0046888460.014
response to external biotic stimulusGO:00432072210.014
metal ion transportGO:00300012890.014
camera type eye developmentGO:0043010480.014
negative regulation of neuron deathGO:1901215690.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
striated muscle tissue developmentGO:0014706580.014
positive regulation of transferase activityGO:0051347810.014
response to bacteriumGO:00096172000.014
cellular response to cytokine stimulusGO:00713451270.014
columnar cuboidal epithelial cell differentiationGO:000206580.014
camera type eye morphogenesisGO:004859320.014
reactive nitrogen species metabolic processGO:200105710.014
wound healingGO:00420601220.014
regulation of canonical wnt signaling pathwayGO:006082840.014
negative regulation of neurogenesisGO:0050768780.013
organic cyclic compound catabolic processGO:19013611750.013
potassium ion transmembrane transportGO:0071805710.013
regulation of growthGO:00400081050.013
respiratory gaseous exchangeGO:000758540.013
response to coldGO:0009409290.013
single organism behaviorGO:00447081300.013
regulation of peptide transportGO:0090087870.013
regulation of kinase activityGO:00435491170.013
gliogenesisGO:0042063930.013
negative regulation of smooth muscle contractionGO:004598670.013
cyclic nucleotide biosynthetic processGO:0009190630.013
apoptotic processGO:00069153810.013
regulation of transferase activityGO:00513381230.013
nucleoside triphosphate catabolic processGO:00091431230.013
negative regulation of transportGO:00510511360.013
response to lipopolysaccharideGO:00324961910.013
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.013
monocarboxylic acid metabolic processGO:00327871520.013
regulation of peptide secretionGO:0002791820.013
catecholamine secretionGO:0050432330.013
negative regulation of protein metabolic processGO:00512481140.013
positive regulation of cell communicationGO:00106472710.013
nucleoside monophosphate metabolic processGO:0009123930.013
reproductive system developmentGO:00614581280.013
purine nucleoside metabolic processGO:00422781690.013
positive regulation of blood circulationGO:1903524650.013
regulation of heart contractionGO:0008016480.013
carbohydrate derivative catabolic processGO:19011361470.013
positive regulation of receptor activityGO:200027340.013
negative regulation of developmental processGO:00510931250.013
cellular response to mechanical stimulusGO:0071260480.013
neuromuscular processGO:005090520.012
organophosphate catabolic processGO:00464341480.012
cellular catabolic processGO:00442482950.012
auditory receptor cell differentiationGO:004249120.012
pyridine containing compound metabolic processGO:0072524320.012
glycosyl compound metabolic processGO:19016571820.012
regulation of cellular component organizationGO:00511283680.012
brain developmentGO:00074202470.012
single organism organelle organizationGO:19025891800.012
purine containing compound biosynthetic processGO:0072522850.012
behavioral response to nicotineGO:003509520.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
response to testosteroneGO:0033574550.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
hepaticobiliary system developmentGO:0061008900.012
cellular component biogenesisGO:00440853680.012
cyclic nucleotide metabolic processGO:0009187800.012
cellular response to organic cyclic compoundGO:00714072020.012
regulation of endocrine processGO:0044060210.012
positive regulation of amine transportGO:0051954260.012
response to hexoseGO:00097461440.012
cellular response to biotic stimulusGO:0071216590.012
regulation of ion transmembrane transportGO:00347651210.012
positive regulation of kinase activityGO:0033674770.012
ribonucleotide biosynthetic processGO:0009260850.012
hematopoietic progenitor cell differentiationGO:000224420.012
mechanoreceptor differentiationGO:004249020.012
cellular nitrogen compound catabolic processGO:00442701630.012
nucleotide catabolic processGO:00091661390.012
regulation of catabolic processGO:00098941130.012
purine ribonucleoside monophosphate metabolic processGO:0009167840.012
microtubule cytoskeleton organizationGO:0000226250.012
immune system processGO:00023762040.011
cell type specific apoptotic processGO:00972851340.011
skeletal system developmentGO:0001501410.011
cytoplasmic transportGO:00164821150.011
endocrine system developmentGO:0035270300.011
positive regulation of neuron differentiationGO:00456661260.011
regulation of cell cycleGO:0051726730.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
reactive oxygen species biosynthetic processGO:190340980.011
inner ear receptor cell differentiationGO:006011320.011
ribonucleoside monophosphate metabolic processGO:0009161880.011
positive regulation of response to stimulusGO:00485842850.011
growthGO:00400071650.011
organic acid biosynthetic processGO:0016053830.011
positive regulation of cell developmentGO:00107201760.011
negative regulation of innate immune responseGO:004582440.011
negative regulation of cell developmentGO:0010721820.011
norepinephrine transportGO:0015874180.011
cellular response to molecule of bacterial originGO:0071219560.011
kidney developmentGO:0001822670.011
heart contractionGO:0060047570.011
regulation of neurotrophin productionGO:003289920.011
purine nucleotide catabolic processGO:00061951360.011
response to vitaminGO:00332731310.011
astrocyte developmentGO:001400240.011
purine ribonucleotide catabolic processGO:00091541360.011
regulation of mapk cascadeGO:00434081160.011
negative regulation of cell communicationGO:00106481580.011
mapk cascadeGO:00001651400.011
response to calcium ionGO:0051592590.011
response to amineGO:0014075460.011
microtubule based processGO:0007017360.011
neuron fate commitmentGO:004866340.011
protein heterooligomerizationGO:0051291890.011
second messenger mediated signalingGO:0019932510.011
cellular response to abiotic stimulusGO:0071214850.011
rho protein signal transductionGO:0007266110.010
inorganic cation transmembrane transportGO:00986622020.010
calcium ion transport into cytosolGO:0060402380.010
regulation of ion transmembrane transporter activityGO:0032412480.010
neurotransmitter uptakeGO:000150430.010
norepinephrine secretionGO:0048243160.010
negative regulation of secretion by cellGO:1903531720.010
nucleobase containing compound catabolic processGO:00346551520.010
central nervous system neuron differentiationGO:0021953170.010
renal sodium excretionGO:0035812200.010
monocarboxylic acid transportGO:0015718520.010

Igsf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.091
disease of anatomical entityDOID:700.091
disease of metabolismDOID:001466700.026
inherited metabolic disorderDOID:65500.024
sensory system diseaseDOID:005015500.018
eye and adnexa diseaseDOID:149200.018
central nervous system diseaseDOID:33100.016
carbohydrate metabolic disorderDOID:297800.016
usher syndromeDOID:005043900.014
cardiovascular system diseaseDOID:128700.014
brain diseaseDOID:93600.013
musculoskeletal system diseaseDOID:1700.012