IMP: Integrative Multi-species Prediction

Rattus norvegicus

12 known processes

Hbg1

hemoglobin, gamma A

(Aliases: Hbe1,Hbb-y)

Ensembl: ENSRNOG00000030879
Entrez: 94164
RGD: 620306
UniProtKB: O88754

Process Predictions
Disease Predictions

Hbg1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to inorganic substance	GO:0010035	377	0.531
regulation of nucleic acid templated transcription	GO:1903506	380	0.409	Mouse
response to extracellular stimulus	GO:0009991	380	0.314
transcription dna templated	GO:0006351	377	0.295	Mouse
oxoacid metabolic process	GO:0043436	290	0.294	Rat
tissue development	GO:0009888	252	0.288
response to metal ion	GO:0010038	253	0.263
positive regulation of signaling	GO:0023056	270	0.260
cellular response to lipid	GO:0071396	201	0.258
regulation of rna metabolic process	GO:0051252	391	0.249	Mouse
cellular response to endogenous stimulus	GO:0071495	377	0.245
response to estrogen	GO:0043627	232	0.208
response to nutrient	GO:0007584	248	0.204
epithelium development	GO:0060429	96	0.188
regulation of molecular function	GO:0065009	398	0.176
response to nutrient levels	GO:0031667	370	0.167
response to acid chemical	GO:0001101	222	0.166
cellular response to oxygen containing compound	GO:1901701	386	0.158
c21 steroid hormone biosynthetic process	GO:0006700	10	0.158
steroid metabolic process	GO:0008202	73	0.155
positive regulation of response to stimulus	GO:0048584	285	0.150
regulation of protein metabolic process	GO:0051246	289	0.150
positive regulation of gene expression	GO:0010628	244	0.144
lipid biosynthetic process	GO:0008610	128	0.144
transcription from rna polymerase ii promoter	GO:0006366	252	0.143	Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.140	Mouse
central nervous system development	GO:0007417	311	0.138
intracellular signal transduction	GO:0035556	314	0.136
cellular ketone metabolic process	GO:0042180	51	0.129
regulation of mapk cascade	GO:0043408	116	0.126
response to corticosteroid	GO:0031960	235	0.125
positive regulation of signal transduction	GO:0009967	175	0.123
positive regulation of biosynthetic process	GO:0009891	319	0.122
negative regulation of macromolecule metabolic process	GO:0010605	260	0.120	Mouse
positive regulation of cell proliferation	GO:0008284	249	0.117
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.112	Mouse
anatomical structure morphogenesis	GO:0009653	298	0.111
positive regulation of cell communication	GO:0010647	271	0.109
regulation of cell proliferation	GO:0042127	359	0.108
rna biosynthetic process	GO:0032774	380	0.107	Mouse
positive regulation of protein modification process	GO:0031401	142	0.106
mapk cascade	GO:0000165	140	0.105
rna metabolic process	GO:0016070	406	0.105	Mouse
negative regulation of cell death	GO:0060548	229	0.104
response to mechanical stimulus	GO:0009612	134	0.103
lipid metabolic process	GO:0006629	283	0.100
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.100
regulation of hormone levels	GO:0010817	187	0.096
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.096
cellular response to organonitrogen compound	GO:0071417	197	0.095
regulation of catalytic activity	GO:0050790	304	0.095
response to vitamin	GO:0033273	131	0.095
cellular component assembly	GO:0022607	360	0.094
carboxylic acid metabolic process	GO:0019752	289	0.091	Rat
regulation of cellular ketone metabolic process	GO:0010565	27	0.087
protein complex assembly	GO:0006461	263	0.085
macromolecular complex subunit organization	GO:0043933	339	0.084
regulation of rna biosynthetic process	GO:2001141	381	0.084	Mouse
cellular response to hormone stimulus	GO:0032870	247	0.083
female pregnancy	GO:0007565	122	0.082
carbohydrate derivative metabolic process	GO:1901135	346	0.079
negative regulation of metabolic process	GO:0009892	331	0.079	Mouse
regulation of multicellular organismal development	GO:2000026	376	0.079
response to wounding	GO:0009611	254	0.076
transmission of nerve impulse	GO:0019226	42	0.076
regulation of phosphorus metabolic process	GO:0051174	349	0.076
regulation of intracellular signal transduction	GO:1902531	218	0.075
chemical homeostasis	GO:0048878	292	0.075
positive regulation of cellular biosynthetic process	GO:0031328	295	0.074
apoptotic process	GO:0006915	381	0.073
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.073
regulation of cellular protein metabolic process	GO:0032268	267	0.073
positive regulation of immunoglobulin production	GO:0002639	4	0.072
positive regulation of protein metabolic process	GO:0051247	178	0.070
response to oxygen levels	GO:0070482	265	0.070
cellular homeostasis	GO:0019725	252	0.069
signal transduction by phosphorylation	GO:0023014	144	0.069
negative regulation of gene expression	GO:0010629	199	0.069	Mouse
cellular response to organic cyclic compound	GO:0071407	202	0.066
response to decreased oxygen levels	GO:0036293	237	0.065
immune response	GO:0006955	104	0.063
homeostatic process	GO:0042592	331	0.062
amine metabolic process	GO:0009308	38	0.062
cellular response to peptide	GO:1901653	133	0.062
positive regulation of molecular function	GO:0044093	230	0.061
cellular amino acid metabolic process	GO:0006520	107	0.059	Rat
regulation of programmed cell death	GO:0043067	341	0.059
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.058
regulation of apoptotic process	GO:0042981	335	0.057
organic acid metabolic process	GO:0006082	292	0.056	Rat
negative regulation of cellular biosynthetic process	GO:0031327	161	0.056	Mouse
positive regulation of rna metabolic process	GO:0051254	203	0.056
regulation of cellular amine metabolic process	GO:0033238	8	0.053
macromolecular complex assembly	GO:0065003	273	0.052
cellular component morphogenesis	GO:0032989	155	0.052
negative regulation of apoptotic process	GO:0043066	181	0.052
cellular amine metabolic process	GO:0044106	38	0.051
small molecule biosynthetic process	GO:0044283	124	0.051
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.051	Mouse
positive regulation of transcription dna templated	GO:0045893	197	0.051
organic substance catabolic process	GO:1901575	316	0.051
positive regulation of phosphorus metabolic process	GO:0010562	262	0.051
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.050
single organism reproductive process	GO:0044702	297	0.050
response to carbohydrate	GO:0009743	183	0.049
positive regulation of phosphorylation	GO:0042327	177	0.049
positive regulation of intracellular signal transduction	GO:1902533	138	0.049
response to peptide hormone	GO:0043434	278	0.048
negative regulation of rna metabolic process	GO:0051253	123	0.048	Mouse
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.048
positive regulation of cellular amine metabolic process	GO:0033240	3	0.048
protein complex subunit organization	GO:0071822	302	0.048
single organism biosynthetic process	GO:0044711	342	0.047
reproductive process	GO:0022414	372	0.047
regulation of phosphate metabolic process	GO:0019220	349	0.047
head development	GO:0060322	247	0.047
ossification	GO:0001503	70	0.047
response to estradiol	GO:0032355	164	0.047
regulation of transcription dna templated	GO:0006355	374	0.047	Mouse
alcohol metabolic process	GO:0006066	77	0.047
multi multicellular organism process	GO:0044706	138	0.046
regulation of immune system process	GO:0002682	123	0.046
epithelial cell differentiation	GO:0030855	71	0.046
cellular response to steroid hormone stimulus	GO:0071383	93	0.046
regulation of cellular amino acid metabolic process	GO:0006521	2	0.045
steroid biosynthetic process	GO:0006694	48	0.045
protein phosphorylation	GO:0006468	345	0.044
positive regulation of developmental process	GO:0051094	283	0.043
connective tissue development	GO:0061448	33	0.042
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.042
positive regulation of rna biosynthetic process	GO:1902680	197	0.041
programmed cell death	GO:0012501	392	0.041
multicellular organism reproduction	GO:0032504	233	0.041
regulation of protein phosphorylation	GO:0001932	183	0.040
positive regulation of protein phosphorylation	GO:0001934	135	0.039
multi organism reproductive process	GO:0044703	262	0.039
regeneration	GO:0031099	163	0.039
muscle system process	GO:0003012	115	0.039
purine ribonucleotide metabolic process	GO:0009150	227	0.038
positive regulation of transport	GO:0051050	245	0.037
positive regulation of phosphate metabolic process	GO:0045937	262	0.037
negative regulation of cellular metabolic process	GO:0031324	281	0.037	Mouse
regulation of protein modification process	GO:0031399	194	0.037
reproduction	GO:0000003	245	0.037
response to cadmium ion	GO:0046686	35	0.037
regulation of tube size	GO:0035150	89	0.037
anterior posterior pattern specification	GO:0009952	1	0.037
neuronal action potential	GO:0019228	35	0.036
negative regulation of response to stimulus	GO:0048585	155	0.036
cellular lipid metabolic process	GO:0044255	208	0.036
glycerolipid metabolic process	GO:0046486	67	0.036
peptidyl amino acid modification	GO:0018193	126	0.036
cellular response to mechanical stimulus	GO:0071260	48	0.036
response to fatty acid	GO:0070542	65	0.035
negative regulation of cell proliferation	GO:0008285	119	0.035
positive regulation of multicellular organismal process	GO:0051240	387	0.035
response to organophosphorus	GO:0046683	102	0.035
regulation of metal ion transport	GO:0010959	118	0.035
response to bacterium	GO:0009617	200	0.035
nucleobase containing small molecule metabolic process	GO:0055086	316	0.034
cell type specific apoptotic process	GO:0097285	134	0.034
positive regulation of catalytic activity	GO:0043085	184	0.033
positive regulation of cellular protein metabolic process	GO:0032270	167	0.033
response to growth factor	GO:0070848	189	0.033
behavior	GO:0007610	205	0.033
cell adhesion	GO:0007155	110	0.032
regulation of phosphorylation	GO:0042325	248	0.031
regulation of cellular component organization	GO:0051128	368	0.031
response to purine containing compound	GO:0014074	126	0.031
cation transport	GO:0006812	382	0.031
multicellular organismal reproductive process	GO:0048609	233	0.031
regulation of transferase activity	GO:0051338	123	0.031
response to ethanol	GO:0045471	162	0.031
response to biotic stimulus	GO:0009607	226	0.030
response to fungicide	GO:0060992	20	0.030
response to hydrogen peroxide	GO:0042542	89	0.030
regulation of ossification	GO:0030278	32	0.030
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.030	Mouse
monocarboxylic acid metabolic process	GO:0032787	152	0.030
androgen metabolic process	GO:0008209	14	0.030
cell projection organization	GO:0030030	302	0.029
purine containing compound metabolic process	GO:0072521	253	0.029
jak stat cascade	GO:0007259	26	0.029
developmental growth	GO:0048589	100	0.029
defense response	GO:0006952	194	0.029
cation homeostasis	GO:0055080	195	0.029
response to transition metal nanoparticle	GO:1990267	122	0.028
regulation of anatomical structure morphogenesis	GO:0022603	141	0.028
regulation of response to external stimulus	GO:0032101	106	0.028
immune system process	GO:0002376	204	0.028
cellular response to nitrogen compound	GO:1901699	210	0.028
response to peptide	GO:1901652	292	0.028
cell morphogenesis	GO:0000902	142	0.027
regulation of response to stress	GO:0080134	126	0.027
negative regulation of biosynthetic process	GO:0009890	168	0.027	Mouse
cellular ion homeostasis	GO:0006873	184	0.027
nucleic acid templated transcription	GO:0097659	379	0.027	Mouse
negative regulation of multicellular organismal process	GO:0051241	203	0.027
cellular response to growth factor stimulus	GO:0071363	162	0.027
nucleotide metabolic process	GO:0009117	279	0.026
ion homeostasis	GO:0050801	212	0.026
glial cell differentiation	GO:0010001	65	0.026
cellular response to abiotic stimulus	GO:0071214	85	0.026
negative regulation of molecular function	GO:0044092	133	0.026
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.026
signal release	GO:0023061	145	0.026
cellular component biogenesis	GO:0044085	368	0.026
developmental process involved in reproduction	GO:0003006	159	0.025
peptidyl tyrosine phosphorylation	GO:0018108	72	0.025
protein complex biogenesis	GO:0070271	263	0.025
cellular response to glucocorticoid stimulus	GO:0071385	68	0.025
response to external biotic stimulus	GO:0043207	221	0.025
skeletal system development	GO:0001501	41	0.024
heart morphogenesis	GO:0003007	3	0.024
positive regulation of cell differentiation	GO:0045597	217	0.024
cardiovascular system development	GO:0072358	134	0.024
striated muscle tissue development	GO:0014706	58	0.024
action potential	GO:0001508	54	0.024
organic hydroxy compound metabolic process	GO:1901615	115	0.023
secretion by cell	GO:0032940	248	0.023
negative regulation of cell differentiation	GO:0045596	99	0.023
positive regulation of cell development	GO:0010720	176	0.023
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.023
negative regulation of programmed cell death	GO:0043069	183	0.023
progesterone biosynthetic process	GO:0006701	3	0.023
positive regulation of immunoglobulin mediated immune response	GO:0002891	2	0.022
fatty acid metabolic process	GO:0006631	99	0.022
ribonucleotide metabolic process	GO:0009259	231	0.022
hormone mediated signaling pathway	GO:0009755	23	0.022
wound healing	GO:0042060	122	0.022
cellular response to corticosteroid stimulus	GO:0071384	69	0.021
response to monosaccharide	GO:0034284	159	0.021
nitrogen compound transport	GO:0071705	229	0.021
response to cytokine	GO:0034097	215	0.021
gland development	GO:0048732	155	0.021
regulation of cell differentiation	GO:0045595	320	0.021
regulation of blood vessel size	GO:0050880	89	0.021
regulation of system process	GO:0044057	208	0.021
cellular chemical homeostasis	GO:0055082	247	0.021
eye morphogenesis	GO:0048592	4	0.021
regulation of synaptic plasticity	GO:0048167	70	0.021
negative regulation of transcription dna templated	GO:0045892	116	0.020	Mouse
non canonical wnt signaling pathway	GO:0035567	3	0.020
immune effector process	GO:0002252	53	0.020
muscle cell differentiation	GO:0042692	52	0.020
immunoglobulin mediated immune response	GO:0016064	4	0.020
regulation of jun kinase activity	GO:0043506	10	0.020
brain development	GO:0007420	247	0.020
negative regulation of protein metabolic process	GO:0051248	114	0.020
negative regulation of cell communication	GO:0010648	158	0.020
multicellular organismal signaling	GO:0035637	44	0.020
regulation of neurogenesis	GO:0050767	247	0.020
gliogenesis	GO:0042063	93	0.020
neuron differentiation	GO:0030182	368	0.020
retina morphogenesis in camera type eye	GO:0060042	1	0.019
organ morphogenesis	GO:0009887	75	0.019
fractalkine metabolic process	GO:0050756	3	0.019
divalent inorganic cation homeostasis	GO:0072507	165	0.019
erk1 and erk2 cascade	GO:0070371	48	0.019
negative regulation of response to external stimulus	GO:0032102	37	0.019
cell projection morphogenesis	GO:0048858	123	0.019
positive regulation of neuron differentiation	GO:0045666	126	0.019
regulation of ion transport	GO:0043269	245	0.019
peptidyl tyrosine modification	GO:0018212	72	0.019
peptide secretion	GO:0002790	86	0.019
catabolic process	GO:0009056	351	0.019
circadian rhythm	GO:0007623	88	0.019
positive regulation of protein serine threonine kinase activity	GO:0071902	52	0.019
regulation of signal transduction	GO:0009966	318	0.019
sensory organ development	GO:0007423	74	0.018
response to alkaloid	GO:0043279	132	0.018
negative regulation of ion transport	GO:0043271	51	0.018
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.018
regulation of epithelial cell proliferation	GO:0050678	49	0.018
regulation of cytokine biosynthetic process	GO:0042035	3	0.018
androgen biosynthetic process	GO:0006702	10	0.018
calcium ion homeostasis	GO:0055074	162	0.018
organophosphate metabolic process	GO:0019637	370	0.018
response to muscle activity involved in regulation of muscle adaptation	GO:0014873	2	0.018
regulation of cell development	GO:0060284	263	0.018
response to mercury ion	GO:0046689	15	0.018
negative regulation of protein maturation	GO:1903318	47	0.018
organic acid biosynthetic process	GO:0016053	83	0.017
cellular response to external stimulus	GO:0071496	118	0.017
positive regulation of nervous system development	GO:0051962	178	0.017
organonitrogen compound biosynthetic process	GO:1901566	167	0.017
phosphatidylethanolamine metabolic process	GO:0046337	1	0.017
regulation of nervous system development	GO:0051960	264	0.017
organ regeneration	GO:0031100	101	0.017
myosin filament organization	GO:0031033	2	0.017
response to lipopolysaccharide	GO:0032496	191	0.017
hormone biosynthetic process	GO:0042446	25	0.017
response to food	GO:0032094	27	0.017
negative regulation of response to wounding	GO:1903035	23	0.017
positive regulation of protein kinase activity	GO:0045860	73	0.017
positive regulation of transferase activity	GO:0051347	81	0.017
negative regulation of developmental process	GO:0051093	125	0.017
regulation of neuron death	GO:1901214	115	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.017	Mouse
cell substrate adhesion	GO:0031589	29	0.016
positive regulation of mapk cascade	GO:0043410	92	0.016
eye development	GO:0001654	50	0.016
response to hypoxia	GO:0001666	231	0.016
cellular response to biotic stimulus	GO:0071216	59	0.016
tube development	GO:0035295	89	0.016
stress activated mapk cascade	GO:0051403	35	0.016
regulation of kinase activity	GO:0043549	117	0.016
anion transport	GO:0006820	178	0.016
negative regulation of catalytic activity	GO:0043086	103	0.015
biological adhesion	GO:0022610	110	0.015
neuron development	GO:0048666	286	0.015
leydig cell differentiation	GO:0033327	8	0.015
response to calcium ion	GO:0051592	59	0.015
nucleoside phosphate metabolic process	GO:0006753	283	0.015
neuron death	GO:0070997	127	0.015
proteolysis	GO:0006508	175	0.015
organic acid transport	GO:0015849	116	0.015
negative regulation of signal transduction	GO:0009968	83	0.015
metal ion homeostasis	GO:0055065	186	0.015
secretion	GO:0046903	307	0.015
sexual reproduction	GO:0019953	148	0.015
response to increased oxygen levels	GO:0036296	45	0.015
cell morphogenesis involved in differentiation	GO:0000904	119	0.015
cellular response to luteinizing hormone stimulus	GO:0071373	5	0.015
regulation of protein maturation	GO:1903317	50	0.014
regulation of cell cycle arrest	GO:0071156	2	0.014
glucocorticoid biosynthetic process	GO:0006704	5	0.014
cell part morphogenesis	GO:0032990	123	0.014
response to glucose	GO:0009749	136	0.014
regulation of cell migration	GO:0030334	128	0.014
positive regulation of cellular component organization	GO:0051130	200	0.014
divalent metal ion transport	GO:0070838	132	0.014
regulation of body fluid levels	GO:0050878	90	0.014
positive regulation of serotonin secretion	GO:0014064	1	0.014
myoblast fusion	GO:0007520	2	0.014
cellular response to stress	GO:0033554	269	0.014
carbohydrate derivative biosynthetic process	GO:1901137	124	0.014
regulation of peptide secretion	GO:0002791	82	0.014
protein oligomerization	GO:0051259	191	0.014
ras protein signal transduction	GO:0007265	29	0.014
spindle organization	GO:0007051	2	0.014
response to activity	GO:0014823	73	0.014
cellular response to acid chemical	GO:0071229	75	0.014
regulation of cell cycle	GO:0051726	73	0.014
cellular response to gonadotropin stimulus	GO:0071371	17	0.014
bmp signaling pathway	GO:0030509	4	0.013
skeletal muscle tissue development	GO:0007519	31	0.013
spermatogenesis	GO:0007283	99	0.013
programmed necrotic cell death	GO:0097300	2	0.013
regulation of protein processing	GO:0070613	50	0.013
carbohydrate metabolic process	GO:0005975	130	0.013
cellular response to dexamethasone stimulus	GO:0071549	36	0.013
response to corticosterone	GO:0051412	40	0.013
cellular response to glucose stimulus	GO:0071333	65	0.013
single organism behavior	GO:0044708	130	0.013
aging	GO:0007568	241	0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.013
regulation of lipid biosynthetic process	GO:0046890	38	0.013
response to mineralocorticoid	GO:0051385	49	0.013
cellular response to metal ion	GO:0071248	55	0.013
embryonic skeletal system development	GO:0048706	3	0.013
male sex differentiation	GO:0046661	64	0.013
regulation of cellular response to stress	GO:0080135	49	0.013
striated muscle cell development	GO:0055002	26	0.013
muscle tissue development	GO:0060537	58	0.013
potassium ion transport	GO:0006813	97	0.013
wnt signaling pathway	GO:0016055	17	0.013
cellular response to inorganic substance	GO:0071241	65	0.013
regulation of erk1 and erk2 cascade	GO:0070372	41	0.013
carboxylic acid biosynthetic process	GO:0046394	83	0.013
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.013
somatic diversification of immune receptors via germline recombination within a single locus	GO:0002562	2	0.013
negative regulation of signaling	GO:0023057	157	0.013
gonad development	GO:0008406	104	0.013
regulation of blood pressure	GO:0008217	83	0.012
regulation of cellular localization	GO:0060341	263	0.012
response to ammonium ion	GO:0060359	71	0.012
regulation of immunoglobulin production	GO:0002637	4	0.012
gamete generation	GO:0007276	124	0.012
regulation of fatty acid metabolic process	GO:0019217	18	0.012
cell cell signaling	GO:0007267	335	0.012
negative regulation of rna biosynthetic process	GO:1902679	118	0.012	Mouse
regulation of map kinase activity	GO:0043405	53	0.012
organic hydroxy compound transport	GO:0015850	77	0.012
positive regulation of map kinase activity	GO:0043406	46	0.012
positive regulation of secretion by cell	GO:1903532	128	0.012
nucleoside monophosphate metabolic process	GO:0009123	93	0.012
cellular response to camp	GO:0071320	26	0.012
purine containing compound biosynthetic process	GO:0072522	85	0.012
cellular calcium ion homeostasis	GO:0006874	160	0.012
innate immune response	GO:0045087	35	0.012
positive regulation of isotype switching	GO:0045830	1	0.012
glucose homeostasis	GO:0042593	75	0.012
regulation of organelle organization	GO:0033043	80	0.012
extracellular matrix constituent secretion	GO:0070278	4	0.012
hormone transport	GO:0009914	121	0.012
regulation of ion homeostasis	GO:2000021	63	0.012
positive regulation of hormone secretion	GO:0046887	65	0.012
positive regulation of cell projection organization	GO:0031346	111	0.012
heart development	GO:0007507	72	0.012
camera type eye development	GO:0043010	48	0.012
forebrain development	GO:0030900	98	0.012
c21 steroid hormone metabolic process	GO:0008207	14	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.012
intracellular protein transport	GO:0006886	79	0.012
positive regulation of apoptotic process	GO:0043065	154	0.012
regulation of response to wounding	GO:1903034	69	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
organophosphate biosynthetic process	GO:0090407	143	0.011
syncytium formation	GO:0006949	4	0.011
purine nucleotide metabolic process	GO:0006163	229	0.011
response to follicle stimulating hormone	GO:0032354	18	0.011
regulation of stem cell differentiation	GO:2000736	2	0.011
cellular nitrogen compound catabolic process	GO:0044270	163	0.011
ribose phosphate biosynthetic process	GO:0046390	87	0.011
protein autophosphorylation	GO:0046777	66	0.011
organelle organization	GO:0006996	266	0.011
positive regulation of kinase activity	GO:0033674	77	0.011
neuron projection morphogenesis	GO:0048812	122	0.011
cytoskeleton organization	GO:0007010	111	0.011
cellular cation homeostasis	GO:0030003	180	0.011
muscle cell development	GO:0055001	26	0.011
fibrinolysis	GO:0042730	2	0.011
cellular response to lipopolysaccharide	GO:0071222	55	0.011
b cell mediated immunity	GO:0019724	4	0.011
response to lead ion	GO:0010288	33	0.011
male gamete generation	GO:0048232	99	0.011
response to glucocorticoid	GO:0051384	223	0.011
response to axon injury	GO:0048678	59	0.011
axis specification	GO:0009798	4	0.011
cognition	GO:0050890	92	0.011
neurological system process	GO:0050877	219	0.011
renal system process	GO:0003014	40	0.011
neuron projection development	GO:0031175	273	0.011
positive regulation of programmed cell death	GO:0043068	157	0.011
cellular response to alcohol	GO:0097306	87	0.011
negative regulation of protein processing	GO:0010955	47	0.011
skeletal system morphogenesis	GO:0048705	12	0.011
cellular modified amino acid metabolic process	GO:0006575	61	0.010	Rat
regulation of muscle system process	GO:0090257	79	0.010
development of primary male sexual characteristics	GO:0046546	59	0.010
male gonad development	GO:0008584	59	0.010
ribose phosphate metabolic process	GO:0019693	235	0.010
vascular process in circulatory system	GO:0003018	96	0.010
regulation of membrane potential	GO:0042391	110	0.010
regulation of isotype switching	GO:0045191	1	0.010
platelet aggregation	GO:0070527	4	0.010
muscle structure development	GO:0061061	87	0.010
female sex differentiation	GO:0046660	59	0.010
dendrite development	GO:0016358	72	0.010
reproductive system development	GO:0061458	128	0.010
growth	GO:0040007	165	0.010
cellular macromolecular complex assembly	GO:0034622	58	0.010
circulatory system process	GO:0003013	183	0.010
regulation of protein serine threonine kinase activity	GO:0071900	64	0.010
cellular response to reactive oxygen species	GO:0034614	55	0.010
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	4	0.010
positive regulation of hydrolase activity	GO:0051345	86	0.010
mitotic cell cycle phase transition	GO:0044772	20	0.010
regulation of stress activated protein kinase signaling cascade	GO:0070302	23	0.010

Hbg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.029
disease of anatomical entity	DOID:7	0.024
musculoskeletal system disease	DOID:17	0.024
steroid inherited metabolic disorder	DOID:1701	0.019
lipid metabolism disorder	DOID:3146	0.019
inherited metabolic disorder	DOID:655	0.019
congenital adrenal hyperplasia	DOID:0050811	0.019
urinary system disease	DOID:18	0.011
kidney disease	DOID:557	0.011
renal tubular transport disease	DOID:447	0.011
connective tissue disease	DOID:65	0.011
nervous system disease	DOID:863	0.010
immune system disease	DOID:2914	0.010

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