Rattus norvegicus

0 known processes

Map3k6

mitogen-activated protein kinase kinase kinase 6

Map3k6 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of apoptotic processGO:00429813350.088
apoptotic processGO:00069153810.074
regulation of cellular component organizationGO:00511283680.073
positive regulation of nitrogen compound metabolic processGO:00511733340.071
response to oxidative stressGO:00069791860.068
response to extracellular stimulusGO:00099913800.066
programmed cell deathGO:00125013920.065
response to lipopolysaccharideGO:00324961910.062
metal ion transportGO:00300012890.061
regulation of cell proliferationGO:00421273590.060
nucleic acid templated transcriptionGO:00976593790.058
negative regulation of metabolic processGO:00098923310.057
organic substance catabolic processGO:19015753160.051
defense responseGO:00069521940.049
regulation of cell differentiationGO:00455953200.048
positive regulation of biosynthetic processGO:00098913190.047
response to bacteriumGO:00096172000.046
negative regulation of cell deathGO:00605482290.045
response to external biotic stimulusGO:00432072210.044
organic acid metabolic processGO:00060822920.043
response to campGO:0051591910.042
gland developmentGO:00487321550.042
positive regulation of phosphorus metabolic processGO:00105622620.042
Human
response to inorganic substanceGO:00100353770.041
response to organophosphorusGO:00466831020.041
cellular response to nitrogen compoundGO:19016992100.041
regulation of rna metabolic processGO:00512523910.040
regulation of rna biosynthetic processGO:20011413810.039
neuron differentiationGO:00301823680.039
multicellular organismal reproductive processGO:00486092330.039
cellular component biogenesisGO:00440853680.039
transcription dna templatedGO:00063513770.038
response to metal ionGO:00100382530.038
regulation of cellular amine metabolic processGO:003323880.038
positive regulation of cell proliferationGO:00082842490.037
negative regulation of macromolecule metabolic processGO:00106052600.037
oxoacid metabolic processGO:00434362900.037
negative regulation of signalingGO:00230571570.036
macromolecular complex subunit organizationGO:00439333390.036
amine metabolic processGO:0009308380.036
cellular response to lipidGO:00713962010.036
response to nutrient levelsGO:00316673700.035
positive regulation of cellular component organizationGO:00511302000.035
rna biosynthetic processGO:00327743800.034
regulation of programmed cell deathGO:00430673410.034
regulation of cellular amino acid metabolic processGO:000652120.034
positive regulation of cellular biosynthetic processGO:00313282950.034
positive regulation of phosphate metabolic processGO:00459372620.033
Human
regulation of nucleic acid templated transcriptionGO:19035063800.033
carbohydrate derivative metabolic processGO:19011353460.033
cellular amine metabolic processGO:0044106380.033
cellular response to oxygen containing compoundGO:19017013860.033
response to peptideGO:19016522920.033
regulation of smooth muscle cell proliferationGO:0048660750.033
catabolic processGO:00090563510.033
positive regulation of multicellular organismal processGO:00512403870.032
negative regulation of biosynthetic processGO:00098901680.032
small gtpase mediated signal transductionGO:0007264360.031
cellular component assemblyGO:00226073600.031
smooth muscle cell proliferationGO:0048659770.030
regulation of cellular ketone metabolic processGO:0010565270.030
response to other organismGO:00517072200.030
positive regulation of molecular functionGO:00440932300.030
Human
response to oxygen levelsGO:00704822650.029
regulation of neuron differentiationGO:00456642080.029
cation transmembrane transportGO:00986552630.029
positive regulation of gene expressionGO:00106282440.029
regulation of cell projection organizationGO:00313441750.029
response to decreased oxygen levelsGO:00362932370.028
tissue developmentGO:00098882520.028
cellular catabolic processGO:00442482950.028
agingGO:00075682410.028
ras protein signal transductionGO:0007265290.028
single organism catabolic processGO:00447122830.028
positive regulation of developmental processGO:00510942830.028
response to biotic stimulusGO:00096072260.028
protein complex subunit organizationGO:00718223020.028
anatomical structure morphogenesisGO:00096532980.028
negative regulation of cell communicationGO:00106481580.028
regulation of phosphate metabolic processGO:00192203490.028
Human
macromolecule localizationGO:00330362520.028
transcription from rna polymerase ii promoterGO:00063662520.028
protein phosphorylationGO:00064683450.027
Human
cell projection organizationGO:00300303020.027
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
rna metabolic processGO:00160704060.027
cellular response to peptideGO:19016531330.027
response to purine containing compoundGO:00140741260.027
organelle organizationGO:00069962660.027
ion transmembrane transportGO:00342203650.027
response to glucocorticoidGO:00513842230.027
cellular ketone metabolic processGO:0042180510.027
positive regulation of apoptotic processGO:00430651540.027
regulation of transcription dna templatedGO:00063553740.026
regulation of transcription from rna polymerase ii promoterGO:00063572340.026
response to acid chemicalGO:00011012220.026
muscle cell proliferationGO:0033002840.026
vesicle mediated transportGO:00161921810.026
positive regulation of cell differentiationGO:00455972170.026
regulation of nervous system developmentGO:00519602640.026
response to estrogenGO:00436272320.026
transmembrane transportGO:00550854120.026
reproductive structure developmentGO:00486081280.026
secretionGO:00469033070.026
cellular response to endogenous stimulusGO:00714953770.026
cellular response to cytokine stimulusGO:00713451270.026
protein complex assemblyGO:00064612630.025
response to alkaloidGO:00432791320.025
cellular amino acid metabolic processGO:00065201070.025
regulation of phosphorus metabolic processGO:00511743490.025
Human
response to molecule of bacterial originGO:00022371940.025
negative regulation of cellular metabolic processGO:00313242810.025
carboxylic acid metabolic processGO:00197522890.025
positive regulation of smooth muscle cell proliferationGO:0048661510.025
ion homeostasisGO:00508012120.025
negative regulation of multicellular organismal processGO:00512412030.025
positive regulation of nervous system developmentGO:00519621780.024
response to peptide hormoneGO:00434342780.024
regulation of response to stressGO:00801341260.024
cellular homeostasisGO:00197252520.024
positive regulation of macromolecule biosynthetic processGO:00105572470.024
single organism biosynthetic processGO:00447113420.024
protein complex biogenesisGO:00702712630.024
localization of cellGO:00516742020.024
regulation of molecular functionGO:00650093980.024
Human
response to hypoxiaGO:00016662310.024
regulation of signal transductionGO:00099663180.023
Human
cation transportGO:00068123820.023
negative regulation of apoptotic processGO:00430661810.023
regulation of cell developmentGO:00602842630.023
g protein coupled receptor signaling pathwayGO:00071862420.023
positive regulation of cellular amine metabolic processGO:003324030.023
regulation of neuron projection developmentGO:00109751610.023
multicellular organism reproductionGO:00325042330.022
intracellular signal transductionGO:00355563140.022
Human
cell motilityGO:00488702020.022
single organism reproductive processGO:00447022970.022
response to nutrientGO:00075842480.022
cellular response to stressGO:00335542690.022
regulation of cellular protein metabolic processGO:00322682670.022
Human
positive regulation of cellular amino acid metabolic processGO:004576410.022
reproductionGO:00000032450.022
positive regulation of neurogenesisGO:00507691650.022
regulation of intracellular signal transductionGO:19025312180.022
Human
negative regulation of gene expressionGO:00106291990.022
monovalent inorganic cation transportGO:00156721720.022
macromolecular complex assemblyGO:00650032730.021
negative regulation of programmed cell deathGO:00430691830.021
immune system processGO:00023762040.021
signal transduction by phosphorylationGO:00230141440.021
Human
response to transition metal nanoparticleGO:19902671220.021
metal ion homeostasisGO:00550651860.021
negative regulation of cellular biosynthetic processGO:00313271610.021
positive regulation of cell deathGO:00109421840.021
positive regulation of neuron differentiationGO:00456661260.020
regulation of protein phosphorylationGO:00019321830.020
Human
regulation of neurogenesisGO:00507672470.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
nucleobase containing small molecule metabolic processGO:00550863160.020
multi organism reproductive processGO:00447032620.020
response to light stimulusGO:0009416520.020
response to ketoneGO:19016541820.020
positive regulation of catalytic activityGO:00430851840.020
Human
regulation of multicellular organismal developmentGO:20000263760.020
regulation of defense responseGO:0031347680.020
positive regulation of protein phosphorylationGO:00019341350.020
Human
neuron projection developmentGO:00311752730.019
response to corticosteroidGO:00319602350.019
reproductive processGO:00224143720.019
positive regulation of rna biosynthetic processGO:19026801970.019
response to interleukin 1GO:0070555550.019
cellular response to organonitrogen compoundGO:00714171970.019
cellular ion homeostasisGO:00068731840.019
regulation of ion transportGO:00432692450.019
regulation of protein metabolic processGO:00512462890.019
Human
nucleoside phosphate metabolic processGO:00067532830.019
response to woundingGO:00096112540.019
locomotionGO:00400112370.019
positive regulation of response to stimulusGO:00485842850.019
Human
protein localizationGO:00081041910.019
response to toxic substanceGO:00096361330.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
inorganic cation transmembrane transportGO:00986622020.018
inflammatory responseGO:00069541500.018
dna metabolic processGO:0006259960.018
organic anion transportGO:00157111320.018
neurological system processGO:00508772190.018
homeostatic processGO:00425923310.018
positive regulation of cell projection organizationGO:00313461110.018
endocytosisGO:0006897840.018
central nervous system developmentGO:00074173110.018
response to ethanolGO:00454711620.017
glycosyl compound metabolic processGO:19016571820.017
response to glucoseGO:00097491360.017
purine nucleotide metabolic processGO:00061632290.017
positive regulation of signal transductionGO:00099671750.017
Human
regulation of purine nucleotide metabolic processGO:19005421150.017
nucleoside metabolic processGO:00091161790.017
secretion by cellGO:00329402480.017
cellular cation homeostasisGO:00300031800.017
purine containing compound metabolic processGO:00725212530.016
positive regulation of phosphorylationGO:00423271770.016
Human
regulation of catalytic activityGO:00507903040.016
Human
response to amineGO:0014075460.016
neuron developmentGO:00486662860.016
positive regulation of transportGO:00510502450.016
response to hexoseGO:00097461440.016
positive regulation of purine nucleotide metabolic processGO:1900544910.016
regulation of response to external stimulusGO:00321011060.016
positive regulation of cell developmentGO:00107201760.016
response to radiationGO:00093141370.016
female pregnancyGO:00075651220.016
regulation of response to woundingGO:1903034690.015
ribonucleotide metabolic processGO:00092592310.015
hair cycle processGO:002240520.015
cellular chemical homeostasisGO:00550822470.015
cation homeostasisGO:00550801950.015
single organism organelle organizationGO:19025891800.015
organonitrogen compound catabolic processGO:19015651790.015
cellular response to abiotic stimulusGO:0071214850.015
response to vitamin dGO:0033280340.015
rhythmic processGO:00485111560.015
positive regulation of nucleotide metabolic processGO:0045981910.015
reactive nitrogen species metabolic processGO:200105710.015
response to ionizing radiationGO:0010212590.015
response to carbohydrateGO:00097431830.015
regulation of synaptic transmissionGO:00508041410.015
urogenital system developmentGO:0001655780.015
regulation of locomotionGO:00400121480.015
cellular response to insulin stimulusGO:0032869810.014
hematopoietic progenitor cell differentiationGO:000224420.014
regulation of neuron deathGO:19012141150.014
purine containing compound biosynthetic processGO:0072522850.014
carbohydrate derivative biosynthetic processGO:19011371240.014
multicellular organismal signalingGO:0035637440.014
response to mechanical stimulusGO:00096121340.014
growthGO:00400071650.014
head developmentGO:00603222470.014
chemical homeostasisGO:00488782920.014
positive regulation of cell communicationGO:00106472710.014
Human
sodium ion transportGO:0006814820.014
positive regulation of programmed cell deathGO:00430681570.014
nucleotide metabolic processGO:00091172790.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
regulation of vesicle mediated transportGO:0060627810.014
ribose phosphate metabolic processGO:00196932350.014
positive regulation of neuron projection developmentGO:0010976990.014
defense response to gram negative bacteriumGO:005082930.014
reproductive system developmentGO:00614581280.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
cellular response to external stimulusGO:00714961180.014
positive regulation of rna metabolic processGO:00512542030.014
negative regulation of protein metabolic processGO:00512481140.014
cell type specific apoptotic processGO:00972851340.013
regulation of kinase activityGO:00435491170.013
Human
gliogenesisGO:0042063930.013
regulation of nucleotide metabolic processGO:00061401170.013
sexual reproductionGO:00199531480.013
regulation of gtpase activityGO:0043087570.013
negative regulation of cellular protein metabolic processGO:00322691060.013
organophosphate biosynthetic processGO:00904071430.013
negative regulation of response to stimulusGO:00485851550.013
negative regulation of rna metabolic processGO:00512531230.013
cellular response to lipopolysaccharideGO:0071222550.013
hair cycleGO:004263330.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
regulation of catabolic processGO:00098941130.013
cellular response to hormone stimulusGO:00328702470.013
cell migrationGO:00164771970.013
regulation of protein modification processGO:00313991940.013
Human
response to cytokineGO:00340972150.013
organophosphate metabolic processGO:00196373700.013
response to estradiolGO:00323551640.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
cellular response to alcoholGO:0097306870.013
rho protein signal transductionGO:0007266110.013
negative regulation of catalytic activityGO:00430861030.013
cytoskeleton organizationGO:00070101110.013
blood circulationGO:00080151830.013
development of primary sexual characteristicsGO:00451371070.013
positive regulation of transcription dna templatedGO:00458931970.012
cellular response to oxidative stressGO:0034599760.012
peptidyl amino acid modificationGO:00181931260.012
molting cycle processGO:002240420.012
response to retinoic acidGO:0032526630.012
ribonucleotide biosynthetic processGO:0009260850.012
intracellular transportGO:00469071850.012
regulation of metal ion transportGO:00109591180.012
cellular response to molecule of bacterial originGO:0071219560.012
negative regulation of transportGO:00510511360.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
neuron deathGO:00709971270.012
negative regulation of transcription dna templatedGO:00458921160.012
gamete generationGO:00072761240.012
reactive oxygen species metabolic processGO:0072593370.012
regulation of fat cell differentiationGO:004559830.012
positive regulation of protein modification processGO:00314011420.012
Human
regulation of ras protein signal transductionGO:0046578450.012
divalent inorganic cation homeostasisGO:00725071650.012
response to growth factorGO:00708481890.012
inorganic ion transmembrane transportGO:00986602290.012
neuronal action potentialGO:0019228350.012
response to hydrogen peroxideGO:0042542890.012
cellular metal ion homeostasisGO:00068751720.012
purine ribonucleoside metabolic processGO:00461281680.012
regulation of protein kinase activityGO:00458591050.012
Human
reactive oxygen species biosynthetic processGO:190340980.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
axis specificationGO:000979840.011
positive regulation of cellular protein metabolic processGO:00322701670.011
Human
female gonad developmentGO:0008585530.011
behaviorGO:00076102050.011
tissue remodelingGO:0048771400.011
response to reactive oxygen speciesGO:00003021200.011
cellular response to organic cyclic compoundGO:00714072020.011
organic acid transportGO:00158491160.011
cell cycle checkpointGO:000007520.011
positive regulation of gtpase activityGO:0043547470.011
cellular calcium ion homeostasisGO:00068741600.011
transmission of nerve impulseGO:0019226420.011
response to activityGO:0014823730.011
regulation of neuron apoptotic processGO:0043523830.011
organic cyclic compound catabolic processGO:19013611750.011
regenerationGO:00310991630.011
developmental process involved in reproductionGO:00030061590.011
cellular response to peptide hormone stimulusGO:00713751200.011
regulation of phosphorylationGO:00423252480.011
Human
molting cycleGO:004230330.011
organonitrogen compound biosynthetic processGO:19015661670.011
regulation of cellular component movementGO:00512701500.011
regulation of endocytosisGO:0030100420.011
positive regulation of defense responseGO:0031349370.011
divalent inorganic cation transportGO:00725111340.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
anion transportGO:00068201780.011
regulation of purine nucleotide catabolic processGO:0033121650.011
wound healingGO:00420601220.011
multi multicellular organism processGO:00447061380.011
salivary gland developmentGO:000743130.011
protein oligomerizationGO:00512591910.011
proteolysisGO:00065081750.011
negative regulation of molecular functionGO:00440921330.010
multicellular organism growthGO:003526410.010
regulation of dna metabolic processGO:0051052600.010
regulation of cellular localizationGO:00603412630.010
guanosine containing compound catabolic processGO:1901069710.010
positive regulation of signalingGO:00230562700.010
Human
muscle structure developmentGO:0061061870.010
regulation of membrane potentialGO:00423911100.010
negative regulation of signal transductionGO:0009968830.010
negative regulation of hormone secretionGO:0046888460.010
regulation of cellular catabolic processGO:00313291010.010
purine ribonucleotide catabolic processGO:00091541360.010
hair follicle developmentGO:000194220.010
carbohydrate derivative catabolic processGO:19011361470.010
positive regulation of catabolic processGO:0009896780.010
neuromuscular processGO:005090520.010
regulation of small gtpase mediated signal transductionGO:0051056480.010
calcium ion homeostasisGO:00550741620.010
regulation of dendrite developmentGO:0050773590.010
bmp signaling pathwayGO:003050940.010
regulation of secretionGO:00510462240.010

Map3k6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.020
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
retinal diseaseDOID:567900.016
eye diseaseDOID:561400.016
eye and adnexa diseaseDOID:149200.016
disease of metabolismDOID:001466700.012
central nervous system diseaseDOID:33100.012