Rattus norvegicus

24 known processes

Cyp2b12

cytochrome P450, family 2, subfamily b, polypeptide 12

Cyp2b12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to extracellular stimulusGO:00099913800.464
response to nutrientGO:00075842480.415
response to nutrient levelsGO:00316673700.361
response to oxygen levelsGO:00704822650.309
positive regulation of multicellular organismal processGO:00512403870.307
response to acid chemicalGO:00011012220.260
Rat
response to corticosteroidGO:00319602350.253
renin angiotensin regulation of aldosterone productionGO:000201830.246
tissue developmentGO:00098882520.242
multi organism reproductive processGO:00447032620.231
Rat
negative regulation of metabolic processGO:00098923310.228
response to decreased oxygen levelsGO:00362932370.206
response to xenobiotic stimulusGO:0009410230.206
Human Rat
response to purine containing compoundGO:00140741260.205
regulation of programmed cell deathGO:00430673410.201
central nervous system developmentGO:00074173110.180
regulation of multicellular organismal developmentGO:20000263760.172
oxoacid metabolic processGO:00434362900.163
response to hypoxiaGO:00016662310.162
response to glucocorticoidGO:00513842230.148
cation transportGO:00068123820.148
response to cytokineGO:00340972150.145
regulation of cell proliferationGO:00421273590.144
cellular response to oxygen containing compoundGO:19017013860.139
oxidation reduction processGO:00551143040.136
response to carbohydrateGO:00097431830.127
blood circulationGO:00080151830.126
negative regulation of macromolecule metabolic processGO:00106052600.126
cellular ketone metabolic processGO:0042180510.123
Human
negative regulation of cellular metabolic processGO:00313242810.118
intracellular transportGO:00469071850.116
ion homeostasisGO:00508012120.115
cellular response to hormone stimulusGO:00328702470.113
response to inorganic substanceGO:00100353770.113
Rat
response to other organismGO:00517072200.113
neurological system processGO:00508772190.109
carboxylic acid metabolic processGO:00197522890.109
ion transmembrane transportGO:00342203650.108
negative regulation of gene expressionGO:00106291990.107
cellular response to endogenous stimulusGO:00714953770.103
homeostatic processGO:00425923310.099
circulatory system processGO:00030131830.099
cellular response to lipidGO:00713962010.092
regulation of cell differentiationGO:00455953200.091
intracellular signal transductionGO:00355563140.089
response to woundingGO:00096112540.087
head developmentGO:00603222470.085
regulation of phosphorus metabolic processGO:00511743490.083
regulation of cell developmentGO:00602842630.081
regulation of cellular protein metabolic processGO:00322682670.081
peptidyl tyrosine modificationGO:0018212720.081
regulation of nervous system developmentGO:00519602640.080
multi multicellular organism processGO:00447061380.079
Rat
cellular homeostasisGO:00197252520.078
response to peptide hormoneGO:00434342780.077
Rat
regulation of protein metabolic processGO:00512462890.075
response to fatty acidGO:0070542650.073
single organism biosynthetic processGO:00447113420.072
transmission of nerve impulseGO:0019226420.072
response to biotic stimulusGO:00096072260.072
vascular process in circulatory systemGO:0003018960.071
response to organophosphorusGO:00466831020.071
single organism reproductive processGO:00447022970.071
behaviorGO:00076102050.071
regulation of systemic arterial blood pressureGO:0003073300.070
response to peptideGO:19016522920.069
Rat
regulation of cellular component organizationGO:00511283680.068
transmembrane transportGO:00550854120.066
regulation of hydrolase activityGO:00513361430.065
positive regulation of biosynthetic processGO:00098913190.065
female pregnancyGO:00075651220.064
Rat
multicellular organismal reproductive processGO:00486092330.064
response to vitaminGO:00332731310.062
response to estradiolGO:00323551640.061
cellular response to organonitrogen compoundGO:00714171970.061
intracellular protein transportGO:0006886790.061
response to campGO:0051591910.060
cellular chemical homeostasisGO:00550822470.060
regulation of signal transductionGO:00099663180.060
multicellular organismal signalingGO:0035637440.059
cellular response to abiotic stimulusGO:0071214850.059
cell growthGO:00160491040.057
regulation of neurogenesisGO:00507672470.057
regulation of blood vessel sizeGO:0050880890.057
regulation of muscle system processGO:0090257790.056
cellular response to external stimulusGO:00714961180.056
cellular amino acid metabolic processGO:00065201070.056
agingGO:00075682410.056
Rat
peptidyl tyrosine phosphorylationGO:0018108720.056
secretionGO:00469033070.055
steroid metabolic processGO:0008202730.054
Human
anatomical structure morphogenesisGO:00096532980.054
chemical homeostasisGO:00488782920.054
growthGO:00400071650.054
organic acid metabolic processGO:00060822920.054
cell projection organizationGO:00300303020.053
positive regulation of nitrogen compound metabolic processGO:00511733340.053
positive regulation of cell proliferationGO:00082842490.053
reproductionGO:00000032450.052
regulation of cellular ketone metabolic processGO:0010565270.052
small gtpase mediated signal transductionGO:0007264360.052
positive regulation of developmental processGO:00510942830.051
regulation of blood circulationGO:19035221100.051
positive regulation of cellular biosynthetic processGO:00313282950.050
multicellular organism reproductionGO:00325042330.050
positive regulation of cell differentiationGO:00455972170.050
cardiovascular system developmentGO:00723581340.050
cellular cation homeostasisGO:00300031800.049
response to radiationGO:00093141370.049
Rat
cellular response to cytokine stimulusGO:00713451270.049
negative regulation of cell proliferationGO:00082851190.049
lipid metabolic processGO:00066292830.048
negative regulation of protein metabolic processGO:00512481140.048
negative regulation of cellular protein metabolic processGO:00322691060.047
cardiac muscle contractionGO:0060048270.047
establishment of protein localization to organelleGO:0072594440.046
sensory perceptionGO:00076001010.046
telencephalon developmentGO:0021537620.045
divalent inorganic cation transportGO:00725111340.044
positive regulation of molecular functionGO:00440932300.044
response to toxic substanceGO:00096361330.043
response to ethanolGO:00454711620.043
Rat
regulation of intracellular signal transductionGO:19025312180.043
cellular response to stressGO:00335542690.042
regulation of catalytic activityGO:00507903040.042
single organism behaviorGO:00447081300.042
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.042
positive regulation of phosphorylationGO:00423271770.041
reproductive processGO:00224143720.041
Rat
neuron developmentGO:00486662860.040
locomotionGO:00400112370.040
muscle system processGO:00030121150.040
brain developmentGO:00074202470.039
nucleobase containing small molecule metabolic processGO:00550863160.039
regulation of phosphorylationGO:00423252480.038
nucleocytoplasmic transportGO:0006913480.038
neuron differentiationGO:00301823680.038
regulation of calcium ion transportGO:0051924770.038
positive regulation of macromolecule biosynthetic processGO:00105572470.038
peptidyl amino acid modificationGO:00181931260.038
protein complex assemblyGO:00064612630.037
protein oligomerizationGO:00512591910.037
steroid biosynthetic processGO:0006694480.036
g protein coupled receptor signaling pathwayGO:00071862420.036
positive regulation of cellular amino acid metabolic processGO:004576410.036
regulation of cellular amino acid metabolic processGO:000652120.036
cellular response to organic cyclic compoundGO:00714072020.036
vasoconstrictionGO:0042310540.035
reactive oxygen species metabolic processGO:0072593370.035
circadian rhythmGO:0007623880.035
circulatory system developmentGO:00723591340.035
response to monosaccharideGO:00342841590.034
response to lipopolysaccharideGO:00324961910.034
protein transportGO:00150311320.034
positive regulation of phosphorus metabolic processGO:00105622620.034
metal ion transportGO:00300012890.033
proteolysisGO:00065081750.033
cellular protein localizationGO:00346131220.033
regulation of blood pressureGO:0008217830.033
regulation of tube sizeGO:0035150890.033
artery smooth muscle contractionGO:001482440.033
muscle contractionGO:0006936880.032
calcium ion homeostasisGO:00550741620.032
cellular metal ion homeostasisGO:00068751720.032
response to dexamethasoneGO:0071548490.032
nucleoside phosphate metabolic processGO:00067532830.032
regulation of protein modification processGO:00313991940.032
positive regulation of signal transductionGO:00099671750.032
positive regulation of response to stimulusGO:00485842850.032
response to mechanical stimulusGO:00096121340.032
regulation of ion transportGO:00432692450.031
negative regulation of developmental processGO:00510931250.031
response to estrogenGO:00436272320.031
lipid biosynthetic processGO:00086101280.031
protein maturationGO:0051604680.031
programmed cell deathGO:00125013920.031
positive regulation of signalingGO:00230562700.031
regulation of molecular functionGO:00650093980.031
establishment of protein localizationGO:00451841410.030
regulation of phosphate metabolic processGO:00192203490.030
forebrain developmentGO:0030900980.030
negative regulation of protein maturationGO:1903318470.030
apoptotic processGO:00069153810.030
protein complex biogenesisGO:00702712630.029
positive regulation of phosphate metabolic processGO:00459372620.029
hepaticobiliary system developmentGO:0061008900.029
Rat
gland developmentGO:00487321550.029
Rat
regulation of metal ion transportGO:00109591180.029
positive regulation of cell deathGO:00109421840.029
regulation of neuron projection developmentGO:00109751610.029
cellular component morphogenesisGO:00329891550.029
catabolic processGO:00090563510.028
Human
cation homeostasisGO:00550801950.028
regulation of transferase activityGO:00513381230.028
neuron projection developmentGO:00311752730.028
defense responseGO:00069521940.027
regulation of kinase activityGO:00435491170.027
positive regulation of programmed cell deathGO:00430681570.027
single organism catabolic processGO:00447122830.027
regulation of cellular component movementGO:00512701500.027
cellular component movementGO:00069282480.027
striated muscle tissue developmentGO:0014706580.027
regulation of protein maturationGO:1903317500.027
cellular amine metabolic processGO:0044106380.026
regulation of apoptotic processGO:00429813350.026
heart morphogenesisGO:000300730.026
sexual reproductionGO:00199531480.026
regulation of cellular amine metabolic processGO:003323880.026
cellular divalent inorganic cation homeostasisGO:00725031620.026
regulation of cell growthGO:0001558850.026
regulation of protein phosphorylationGO:00019321830.025
cellular sodium ion homeostasisGO:000688340.025
calcium ion transportGO:00068161310.025
response to activityGO:0014823730.025
regulation of vasoconstrictionGO:0019229440.025
protein import into nucleusGO:0006606350.025
amine metabolic processGO:0009308380.025
cellular response to glucocorticoid stimulusGO:0071385680.025
positive regulation of cell communicationGO:00106472710.025
positive regulation of long term synaptic potentiationGO:190027340.025
positive regulation of cellular amine metabolic processGO:003324030.024
protein phosphorylationGO:00064683450.024
regulation of protein processingGO:0070613500.024
negative regulation of protein processingGO:0010955470.024
cardiocyte differentiationGO:0035051220.024
protein processingGO:0016485680.024
regulation of system processGO:00440572080.024
detection of stimulusGO:0051606240.024
response to hexoseGO:00097461440.024
metal ion homeostasisGO:00550651860.024
response to molecule of bacterial originGO:00022371940.024
regulation of anatomical structure sizeGO:00900661350.024
response to chromateGO:004668730.024
heart developmentGO:0007507720.024
regulation of cellular localizationGO:00603412630.023
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.023
cellular nitrogen compound catabolic processGO:00442701630.023
calcitriol biosynthetic process from calciolGO:003637820.023
regulation of neuron differentiationGO:00456642080.023
hormone metabolic processGO:0042445690.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
single organism cellular localizationGO:19025801020.023
negative regulation of multicellular organismal processGO:00512412030.022
negative regulation of signal transductionGO:0009968830.022
response to gonadotropinGO:0034698340.022
hormone biosynthetic processGO:0042446250.022
cytoplasmic transportGO:00164821150.022
cellular response to campGO:0071320260.022
regulation of reactive oxygen species metabolic processGO:2000377260.022
long chain fatty acid metabolic processGO:0001676320.022
organophosphate metabolic processGO:00196373700.022
positive regulation of renin secretion into blood streamGO:190013510.022
heterocycle catabolic processGO:00467001670.022
regulation of protein kinase activityGO:00458591050.021
organic cyclic compound catabolic processGO:19013611750.021
rhythmic processGO:00485111560.021
response to reactive oxygen speciesGO:00003021200.021
Rat
positive regulation of protein phosphorylationGO:00019341350.021
protein localization to nucleusGO:0034504390.021
negative regulation of proteolysisGO:0045861410.021
multicellular organism growthGO:003526410.021
regulation of the force of heart contraction by chemical signalGO:000305720.021
striated muscle cell developmentGO:0055002260.021
negative regulation of uterine smooth muscle contractionGO:007047320.021
purine containing compound metabolic processGO:00725212530.021
protein localizationGO:00081041910.020
response to growth factorGO:00708481890.020
regulation of peptidase activityGO:0052547550.020
response to vitamin dGO:0033280340.020
striated muscle contractionGO:0006941440.020
positive regulation of cell developmentGO:00107201760.020
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.020
negative regulation of response to stimulusGO:00485851550.020
cellular response to reactive oxygen speciesGO:0034614550.020
immune responseGO:00069551040.020
regulation of phospholipase activityGO:0010517120.020
cation transmembrane transportGO:00986552630.019
positive regulation of transferase activityGO:0051347810.019
positive regulation of transportGO:00510502450.019
cellular catabolic processGO:00442482950.019
Human
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.019
organic substance catabolic processGO:19015753160.018
muscle tissue developmentGO:0060537580.018
connective tissue developmentGO:0061448330.018
jak stat cascadeGO:0007259260.018
organic acid biosynthetic processGO:0016053830.018
positive regulation of blood circulationGO:1903524650.018
negative regulation of catalytic activityGO:00430861030.018
regulation of nucleic acid templated transcriptionGO:19035063800.018
positive regulation of extracellular matrix organizationGO:190305540.018
cellular lipid metabolic processGO:00442552080.018
cellular response to peptide hormone stimulusGO:00713751200.018
reactive oxygen species biosynthetic processGO:190340980.017
positive regulation of protein kinase activityGO:0045860730.017
negative regulation of neurogenesisGO:0050768780.017
positive regulation of the force of heart contraction by epinephrineGO:000305910.017
gliogenesisGO:0042063930.017
regulation of neurological system processGO:0031644430.017
cellular response to nitrogen compoundGO:19016992100.017
cellular response to insulin stimulusGO:0032869810.017
regulation of catabolic processGO:00098941130.017
negative regulation of chronic inflammatory responseGO:000267720.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
developmental growthGO:00485891000.017
renal system process involved in regulation of systemic arterial blood pressureGO:0003071140.017
positive regulation of transcription factor import into nucleusGO:004299340.017
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressureGO:000202510.017
response to insulinGO:00328681330.017
Rat
small molecule biosynthetic processGO:00442831240.017
insecticide metabolic processGO:001714340.017
cellular ion homeostasisGO:00068731840.017
neuronal action potentialGO:0019228350.016
ossificationGO:0001503700.016
regulation of endopeptidase activityGO:0052548510.016
ras protein signal transductionGO:0007265290.016
regulation of cyclic nucleotide metabolic processGO:0030799510.016
single organism intracellular transportGO:19025821660.016
response to glucoseGO:00097491360.016
negative regulation of peptidase activityGO:0010466380.016
negative regulation of vasculature developmentGO:1901343110.016
limbic system developmentGO:0021761380.016
protein importGO:0017038370.016
synaptic transmissionGO:00072682350.016
cardiac cell developmentGO:0055006160.016
negative regulation of epithelial cell proliferationGO:0050680160.016
cellular response to mechanical stimulusGO:0071260480.016
positive regulation of cellular protein metabolic processGO:00322701670.016
negative regulation of cellular biosynthetic processGO:00313271610.016
regulation of lipid metabolic processGO:0019216680.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.016
regulation of cell activationGO:0050865500.016
negative regulation of signalingGO:00230571570.016
regulation of cell projection organizationGO:00313441750.015
response to oxidative stressGO:00069791860.015
Rat
anterior posterior pattern specificationGO:000995210.015
organophosphate biosynthetic processGO:00904071430.015
tonic smooth muscle contractionGO:001482040.015
nuclear importGO:0051170350.015
localization of cellGO:00516742020.015
cellular response to interleukin 1GO:0071347370.015
response to bacteriumGO:00096172000.015
aromatic compound catabolic processGO:00194391680.015
gamete generationGO:00072761240.015
negative regulation of transcription dna templatedGO:00458921160.015
response to antibioticGO:0046677390.015
regulation of cellular catabolic processGO:00313291010.015
positive regulation of immune system processGO:0002684900.015
divalent metal ion transportGO:00708381320.015
muscle cell developmentGO:0055001260.015
positive regulation of hydrolase activityGO:0051345860.015
positive regulation of neuron differentiationGO:00456661260.015
regulation of synaptic plasticityGO:0048167700.015
organic hydroxy compound transportGO:0015850770.015
positive regulation of apoptotic processGO:00430651540.015
response to corticosteroneGO:0051412400.015
positive regulation of catalytic activityGO:00430851840.014
reactive nitrogen species metabolic processGO:200105710.014
phenol containing compound biosynthetic processGO:004618990.014
Rat
positive regulation of protein modification processGO:00314011420.014
negative regulation of cell communicationGO:00106481580.014
positive regulation of lipid biosynthetic processGO:0046889250.014
drug catabolic processGO:004273710.014
Human
protein homooligomerizationGO:0051260910.014
response to interleukin 1GO:0070555550.014
cardiac muscle tissue developmentGO:0048738260.014
cognitionGO:0050890920.014
positive regulation of kinase activityGO:0033674770.014
regulation of proteolysisGO:0030162660.014
rho protein signal transductionGO:0007266110.014
nucleic acid templated transcriptionGO:00976593790.014
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
t cell tolerance inductionGO:000251730.014
divalent inorganic cation homeostasisGO:00725071650.014
ribose phosphate metabolic processGO:00196932350.014
purine nucleoside metabolic processGO:00422781690.014
extracellular matrix constituent secretionGO:007027840.014
protein localization to organelleGO:0033365570.013
cytokine productionGO:0001816610.013
muscle structure developmentGO:0061061870.013
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.013
triglyceride metabolic processGO:0006641210.013
Rat
cellular response to growth factor stimulusGO:00713631620.013
nuclear transportGO:0051169490.013
maintenance of locationGO:0051235170.013
positive regulation of immunoglobulin productionGO:000263940.013
male gamete generationGO:0048232990.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
spermatogenesisGO:0007283990.013
cellular response to corticosteroid stimulusGO:0071384690.013
response to alkaloidGO:00432791320.013
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.013
organonitrogen compound catabolic processGO:19015651790.013
urinary tract smooth muscle contractionGO:001484840.013
positive regulation of the force of heart contraction by chemical signalGO:000309920.013
monocarboxylic acid metabolic processGO:00327871520.013
regulation of immunoglobulin productionGO:000263740.013
taxisGO:0042330670.013
negative regulation of biosynthetic processGO:00098901680.013
positive regulation of jak stat cascadeGO:0046427190.013
cellular response to peptideGO:19016531330.013
myosin filament assemblyGO:003103410.012
cellular response to nutrient levelsGO:0031669600.012
neuron deathGO:00709971270.012
cellular modified amino acid metabolic processGO:0006575610.012
regulation of lipid biosynthetic processGO:0046890380.012
regulation of anatomical structure morphogenesisGO:00226031410.012
negative regulation of phosphorus metabolic processGO:0010563800.012
response to muscle activity involved in regulation of muscle adaptationGO:001487320.012
smooth muscle contractionGO:0006939370.012
nucleotide biosynthetic processGO:0009165980.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.012
response to metal ionGO:00100382530.012
Rat
fertilizationGO:000956630.012
nucleobase containing compound catabolic processGO:00346551520.012
cell type specific apoptotic processGO:00972851340.012
response to ketoneGO:19016541820.012
Rat
organic hydroxy compound metabolic processGO:19016151150.012
Rat
mapk cascadeGO:00001651400.012
positive regulation of lipid metabolic processGO:0045834330.012
defense response to gram negative bacteriumGO:005082930.012
regulation of immune system processGO:00026821230.012
regulation of tolerance induction dependent upon immune responseGO:000265210.012
cellular calcium ion homeostasisGO:00068741600.012
regulation of transmembrane transportGO:00347621220.012
positive regulation of growthGO:0045927550.012
macromolecule localizationGO:00330362520.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
purine containing compound biosynthetic processGO:0072522850.011
negative regulation of nervous system developmentGO:0051961790.011
cellular response to steroid hormone stimulusGO:0071383930.011
respiratory system processGO:000301630.011
positive regulation of interferon gamma productionGO:003272920.011
negative regulation of phosphorylationGO:0042326570.011
regulation of dendrite developmentGO:0050773590.011
regulation of body fluid levelsGO:0050878900.011
protein targeting to nucleusGO:0044744350.011
positive regulation of intracellular signal transductionGO:19025331380.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
monocarboxylic acid biosynthetic processGO:0072330480.011
liver developmentGO:0001889900.011
Rat
response to external biotic stimulusGO:00432072210.011
positive regulation of neurogenesisGO:00507691650.011
norepinephrine secretionGO:0048243160.011
carbohydrate homeostasisGO:0033500750.011
regulation of membrane potentialGO:00423911100.011
cardiac muscle cell developmentGO:0055013160.011
inflammatory responseGO:00069541500.011
renin secretion into blood streamGO:000200110.011
cell activationGO:0001775970.011
nucleotide metabolic processGO:00091172790.011
astrocyte developmentGO:001400240.011
axon developmentGO:0061564960.011
epithelial cell differentiationGO:0030855710.011
regulation of mapk cascadeGO:00434081160.011
negative regulation of protein phosphorylationGO:0001933440.011
urogenital system developmentGO:0001655780.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
vasodilationGO:0042311440.011
hippocampus developmentGO:0021766300.011
cell morphogenesisGO:00009021420.011
purine nucleotide biosynthetic processGO:0006164830.010
muscle cell differentiationGO:0042692520.010
sleepGO:0030431300.010
response to retinoic acidGO:0032526630.010
regulation of renin secretion into blood streamGO:190013310.010
action potentialGO:0001508540.010
norepinephrine transportGO:0015874180.010
sulfur compound metabolic processGO:0006790700.010
cell motilityGO:00488702020.010
protein targetingGO:0006605610.010
regulation of dna metabolic processGO:0051052600.010
endocrine processGO:0050886320.010
erk1 and erk2 cascadeGO:0070371480.010

Cyp2b12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.043
musculoskeletal system diseaseDOID:1700.041
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.033
inherited metabolic disorderDOID:65500.026
congenital adrenal hyperplasiaDOID:005081100.026
lipid metabolism disorderDOID:314600.026
steroid inherited metabolic disorderDOID:170100.026
connective tissue diseaseDOID:6500.023