Rattus norvegicus

166 known processes

Apoe

apolipoprotein E

(Aliases: APOEA)

Apoe biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo implantationGO:0007566150.389
regulation of glycoprotein metabolic processGO:190301860.348
response to nutrient levelsGO:00316673700.238
regulation of cell differentiationGO:00455953200.222
sensory organ developmentGO:0007423740.208
central nervous system developmentGO:00074173110.199
reproductive processGO:00224143720.199
single organism reproductive processGO:00447022970.190
single organism behaviorGO:00447081300.185
response to extracellular stimulusGO:00099913800.178
negative regulation of cell deathGO:00605482290.178
response to other organismGO:00517072200.178
tissue developmentGO:00098882520.174
response to glucocorticoidGO:00513842230.167
response to biotic stimulusGO:00096072260.157
regulation of cell proliferationGO:00421273590.152
response to metal ionGO:00100382530.138
cellular catabolic processGO:00442482950.135
regulation of multicellular organismal developmentGO:20000263760.126
response to woundingGO:00096112540.117
positive regulation of cell differentiationGO:00455972170.114
brain developmentGO:00074202470.114
response to chromateGO:004668730.112
extracellular fibril organizationGO:004320610.110
cell projection organizationGO:00300303020.109
response to estradiolGO:00323551640.109
head developmentGO:00603222470.107
development of primary sexual characteristicsGO:00451371070.104
agingGO:00075682410.098
reproductive structure developmentGO:00486081280.095
positive regulation of developmental processGO:00510942830.094
collagen catabolic processGO:003057420.093
developmental process involved in reproductionGO:00030061590.091
multi organism reproductive processGO:00447032620.090
multi multicellular organism processGO:00447061380.084
cellular amide metabolic processGO:0043603440.078
reproductive system developmentGO:00614581280.077
response to external biotic stimulusGO:00432072210.076
regulation of protein metabolic processGO:00512462890.076
rhythmic processGO:00485111560.074
neuron differentiationGO:00301823680.072
behaviorGO:00076102050.069
male gonad developmentGO:0008584590.069
male sex differentiationGO:0046661640.068
epithelium developmentGO:0060429960.064
salivary gland developmentGO:000743130.064
protein maturationGO:0051604680.064
positive regulation of neurogenesisGO:00507691650.064
positive regulation of nervous system developmentGO:00519621780.063
negative regulation of multicellular organismal metabolic processGO:004425240.062
negative regulation of cellular protein metabolic processGO:00322691060.062
catabolic processGO:00090563510.060
response to lead ionGO:0010288330.058
proteolysisGO:00065081750.057
neuron developmentGO:00486662860.054
response to campGO:0051591910.054
reproductionGO:00000032450.053
positive regulation of cell developmentGO:00107201760.052
response to organophosphorusGO:00466831020.052
response to inorganic substanceGO:00100353770.050
gonad developmentGO:00084061040.050
positive regulation of neuron projection developmentGO:0010976990.050
nitrogen compound transportGO:00717052290.050
multicellular organism reproductionGO:00325042330.050
development of primary male sexual characteristicsGO:0046546590.050
response to peptideGO:19016522920.049
regulation of ion transportGO:00432692450.048
response to ketoneGO:19016541820.048
regulation of establishment of planar polarityGO:009017520.048
response to corticosteroidGO:00319602350.047
anatomical structure morphogenesisGO:00096532980.046
eye developmentGO:0001654500.046
neurological system processGO:00508772190.046
regulation of myeloid cell differentiationGO:0045637120.045
circadian sleep wake cycleGO:0042745230.045
female pregnancyGO:00075651220.045
regulation of immune responseGO:0050776550.044
regulation of programmed cell deathGO:00430673410.044
negative regulation of developmental processGO:00510931250.042
response to purine containing compoundGO:00140741260.042
response to acid chemicalGO:00011012220.042
multicellular organismal catabolic processGO:004424320.040
response to estrogenGO:00436272320.040
negative regulation of response to stimulusGO:00485851550.040
negative regulation of cellular metabolic processGO:00313242810.040
circadian sleep wake cycle sleepGO:0050802210.039
circadian rhythmGO:0007623880.039
sexual reproductionGO:00199531480.039
negative regulation of protein metabolic processGO:00512481140.038
response to nutrientGO:00075842480.038
single organism catabolic processGO:00447122830.037
regulation of cellular protein metabolic processGO:00322682670.037
positive regulation of cell proliferationGO:00082842490.035
negative regulation of molecular functionGO:00440921330.035
sex differentiationGO:00075481130.035
negative regulation of multicellular organismal processGO:00512412030.034
response to carbohydrateGO:00097431830.033
neuron projection developmentGO:00311752730.033
cell projection morphogenesisGO:00488581230.033
tissue remodelingGO:0048771400.032
negative regulation of macromolecule metabolic processGO:00106052600.032
regulation of immune system processGO:00026821230.032
negative regulation of metabolic processGO:00098923310.031
protein processingGO:0016485680.031
negative regulation of collagen metabolic processGO:001071340.031
chemical homeostasisGO:00488782920.031
response to bacteriumGO:00096172000.030
negative regulation of innate immune responseGO:004582440.030
neuronal action potentialGO:0019228350.030
response to vitaminGO:00332731310.030
positive regulation of response to stimulusGO:00485842850.030
regulation of neurogenesisGO:00507672470.029
response to hydrogen peroxideGO:0042542890.029
rhythmic behaviorGO:0007622240.029
positive regulation of multicellular organismal processGO:00512403870.029
complement activationGO:0006956110.029
homeostatic processGO:00425923310.029
regulation of nervous system developmentGO:00519602640.028
negative regulation of protein processingGO:0010955470.028
regulation of anatomical structure morphogenesisGO:00226031410.028
regulation of neuron projection developmentGO:00109751610.028
regulation of protein processingGO:0070613500.027
cellular response to stressGO:00335542690.027
response to monosaccharideGO:00342841590.027
heart morphogenesisGO:000300730.026
positive regulation of cell projection organizationGO:00313461110.026
response to molecule of bacterial originGO:00022371940.026
regulation of neuron differentiationGO:00456642080.026
elastin metabolic processGO:005154110.026
negative regulation of protein maturationGO:1903318470.025
multicellular organismal reproductive processGO:00486092330.025
response to hypoxiaGO:00016662310.025
gamete generationGO:00072761240.025
programmed cell deathGO:00125013920.025
localization of cellGO:00516742020.025
carbohydrate derivative metabolic processGO:19011353460.024
negative regulation of apoptotic processGO:00430661810.024
cellular response to oxidative stressGO:0034599760.024
defense responseGO:00069521940.024
negative regulation of peptidase activityGO:0010466380.023
negative regulation of programmed cell deathGO:00430691830.023
negative regulation of immune system processGO:0002683390.023
regulation of molecular functionGO:00650093980.022
positive regulation of neuron differentiationGO:00456661260.022
negative regulation of endopeptidase activityGO:0010951360.022
regulation of catabolic processGO:00098941130.021
cellular response to endogenous stimulusGO:00714953770.021
response to lipopolysaccharideGO:00324961910.021
acute inflammatory responseGO:0002526580.021
regulation of fibrinolysisGO:005191720.021
respiratory system developmentGO:0060541450.021
regulation of proteolysisGO:0030162660.021
cellular component movementGO:00069282480.020
regulation of cell developmentGO:00602842630.020
cell killingGO:0001906130.020
cellular chemical homeostasisGO:00550822470.020
regulation of metal ion transportGO:00109591180.020
lipid transportGO:0006869610.020
regulation of protein maturationGO:1903317500.020
kidney developmentGO:0001822670.020
negative regulation of proteolysisGO:0045861410.020
negative regulation of gene expressionGO:00106291990.020
circadian sleep wake cycle processGO:0022410210.020
spermatogenesisGO:0007283990.020
regulation of defense responseGO:0031347680.019
regulation of cellular catabolic processGO:00313291010.019
organic substance catabolic processGO:19015753160.019
regulation of cell projection organizationGO:00313441750.018
axon developmentGO:0061564960.018
activation of immune responseGO:0002253260.018
hair cycle processGO:002240520.017
regulation of blood pressureGO:0008217830.017
neuron projection morphogenesisGO:00488121220.017
response to oxygen levelsGO:00704822650.017
cell morphogenesisGO:00009021420.017
regulation of cellular component organizationGO:00511283680.017
response to decreased oxygen levelsGO:00362932370.017
cell motilityGO:00488702020.017
response to retinoic acidGO:0032526630.017
response to reactive oxygen speciesGO:00003021200.017
epithelial cell differentiationGO:0030855710.016
immune system processGO:00023762040.016
regulation of catalytic activityGO:00507903040.016
carbohydrate derivative catabolic processGO:19011361470.016
positive regulation of nitrogen compound metabolic processGO:00511733340.016
hormone metabolic processGO:0042445690.015
dna replicationGO:0006260370.015
endocytosisGO:0006897840.015
organic acid metabolic processGO:00060822920.015
apoptotic processGO:00069153810.015
cardiovascular system developmentGO:00723581340.015
mapk cascadeGO:00001651400.015
ossificationGO:0001503700.015
multicellular organismal signalingGO:0035637440.014
male gamete generationGO:0048232990.014
regulation of apoptotic processGO:00429813350.014
regulation of peptidase activityGO:0052547550.014
renal system developmentGO:0072001670.014
sleepGO:0030431300.014
cytosolic calcium ion homeostasisGO:00514801400.014
cellular response to oxygen containing compoundGO:19017013860.014
organ morphogenesisGO:0009887750.014
immune effector processGO:0002252530.014
response to potassium ionGO:003586490.014
macromolecule catabolic processGO:0009057580.014
cellular response to gonadotropin stimulusGO:0071371170.013
circadian behaviorGO:0048512240.013
cellular homeostasisGO:00197252520.013
gland developmentGO:00487321550.013
inflammatory responseGO:00069541500.013
cellular calcium ion homeostasisGO:00068741600.013
regulation of proteasomal protein catabolic processGO:006113640.013
cell type specific apoptotic processGO:00972851340.013
neuromuscular processGO:005090520.013
response to insulinGO:00328681330.013
rna localizationGO:000640340.013
nucleobase containing small molecule metabolic processGO:00550863160.013
immunoglobulin mediated immune responseGO:001606440.013
regulation of endopeptidase activityGO:0052548510.012
sulfur compound metabolic processGO:0006790700.012
cellular hormone metabolic processGO:0034754490.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
response to toxic substanceGO:00096361330.012
negative regulation of catalytic activityGO:00430861030.012
metal ion transportGO:00300012890.012
response to hexoseGO:00097461440.012
cellular response to lipidGO:00713962010.012
cell part morphogenesisGO:00329901230.012
metal ion homeostasisGO:00550651860.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.012
innate immune responseGO:0045087350.012
cellular response to alcoholGO:0097306870.012
response to oxidative stressGO:00069791860.012
response to amino acidGO:0043200750.011
negative regulation of cell proliferationGO:00082851190.011
cellular amino acid metabolic processGO:00065201070.011
cellular response to hormone stimulusGO:00328702470.011
regulation of tolerance induction to nonself antigenGO:000265510.011
negative regulation of myeloid cell differentiationGO:004563830.011
organelle organizationGO:00069962660.011
ion homeostasisGO:00508012120.011
purine ribonucleotide metabolic processGO:00091502270.011
organelle inheritanceGO:004830820.011
immune responseGO:00069551040.011
ear developmentGO:0043583210.011
glutamine family amino acid metabolic processGO:0009064150.011
astrocyte developmentGO:001400240.011
monovalent inorganic cation transportGO:00156721720.011
cellular response to follicle stimulating hormone stimulusGO:0071372130.011
isoprenoid metabolic processGO:0006720450.010
molting cycleGO:004230330.010
b cell mediated immunityGO:001972440.010
cellular response to molecule of bacterial originGO:0071219560.010
cellular response to nitrogen compoundGO:19016992100.010
cation transportGO:00068123820.010
positive regulation of programmed cell deathGO:00430681570.010
blood circulationGO:00080151830.010
cellular macromolecule catabolic processGO:0044265290.010
response to antibioticGO:0046677390.010

Apoe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.242
nervous system diseaseDOID:86300.118
sensory system diseaseDOID:005015500.118
disease of anatomical entityDOID:700.118
eye and adnexa diseaseDOID:149200.118
eye diseaseDOID:561400.079
degeneration of macula and posterior poleDOID:200700.079
macular degenerationDOID:444800.079
retinal diseaseDOID:567900.079
retinal degenerationDOID:846600.079
age related macular degenerationDOID:1087100.079
acquired metabolic diseaseDOID:006015800.053
inherited metabolic disorderDOID:65500.035
lysosomal storage diseaseDOID:321100.012
metal metabolism disorderDOID:89600.011