| regulation of peptide secretion | GO:0002791 | 82 | 0.092 | |
| regulation of hormone secretion | GO:0046883 | 106 | 0.079 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.074 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.070 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.061 | |
| positive regulation of multicellular organismal process | GO:0051240 | 387 | 0.059 | |
| leukocyte activation | GO:0045321 | 76 | 0.058 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 242 | 0.054 | |
| response to bacterium | GO:0009617 | 200 | 0.051 | |
| chemical homeostasis | GO:0048878 | 292 | 0.050 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.046 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.046 | |
| adenylate cyclase modulating g protein coupled receptor signaling pathway | GO:0007188 | 51 | 0.046 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.046 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.045 | |
| secretion | GO:0046903 | 307 | 0.042 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.041 | |
| positive regulation of ion transport | GO:0043270 | 94 | 0.041 | |
| embryonic skeletal system development | GO:0048706 | 3 | 0.039 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.039 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.037 | |
| protein phosphorylation | GO:0006468 | 345 | 0.036 | |
| g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger | GO:0007187 | 55 | 0.035 | |
| positive regulation of signaling | GO:0023056 | 270 | 0.035 | |
| response to hypoxia | GO:0001666 | 231 | 0.034 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.034 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.033 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.033 | |
| camp metabolic process | GO:0046058 | 63 | 0.032 | |
| cellular calcium ion homeostasis | GO:0006874 | 160 | 0.031 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.031 | |
| negative regulation of immune system process | GO:0002683 | 39 | 0.030 | |
| intracellular transport | GO:0046907 | 185 | 0.030 | |
| immune system process | GO:0002376 | 204 | 0.029 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.029 | |
| single organism organelle organization | GO:1902589 | 180 | 0.029 | |
| programmed cell death | GO:0012501 | 392 | 0.029 | |
| cellular homeostasis | GO:0019725 | 252 | 0.029 | |
| regulation of peptide transport | GO:0090087 | 87 | 0.028 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.028 | |
| response to oxygen levels | GO:0070482 | 265 | 0.028 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.028 | |
| cyclic nucleotide metabolic process | GO:0009187 | 80 | 0.027 | |
| reproductive process | GO:0022414 | 372 | 0.027 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 162 | 0.027 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.027 | |
| cellular component assembly | GO:0022607 | 360 | 0.027 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.027 | |
| reactive oxygen species metabolic process | GO:0072593 | 37 | 0.027 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.026 | |
| amine metabolic process | GO:0009308 | 38 | 0.026 | |
| positive regulation of transport | GO:0051050 | 245 | 0.026 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.025 | |
| regulation of secretion by cell | GO:1903530 | 208 | 0.025 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 3 | 0.025 | |
| response to growth factor | GO:0070848 | 189 | 0.025 | |
| cellular ion homeostasis | GO:0006873 | 184 | 0.024 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.024 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.024 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 26 | 0.024 | |
| protein transport | GO:0015031 | 132 | 0.024 | |
| homeostatic process | GO:0042592 | 331 | 0.024 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.024 | |
| organelle organization | GO:0006996 | 266 | 0.024 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.023 | |
| cellular protein localization | GO:0034613 | 122 | 0.023 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.023 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.023 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.023 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.023 | |
| positive regulation of secretion by cell | GO:1903532 | 128 | 0.023 | |
| regulation of response to stress | GO:0080134 | 126 | 0.023 | |
| cell activation | GO:0001775 | 97 | 0.022 | |
| apoptotic process | GO:0006915 | 381 | 0.022 | |
| cellular response to growth factor stimulus | GO:0071363 | 162 | 0.022 | |
| response to peptide hormone | GO:0043434 | 278 | 0.022 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.022 | |
| cellular macromolecule localization | GO:0070727 | 122 | 0.022 | |
| monocarboxylic acid metabolic process | GO:0032787 | 152 | 0.022 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.022 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.022 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.021 | |
| divalent inorganic cation transport | GO:0072511 | 134 | 0.021 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.021 | |
| endomembrane system organization | GO:0010256 | 48 | 0.021 | |
| positive regulation of nervous system development | GO:0051962 | 178 | 0.021 | |
| divalent inorganic cation homeostasis | GO:0072507 | 165 | 0.021 | |
| negative regulation of secretion | GO:0051048 | 82 | 0.021 | |
| macromolecule localization | GO:0033036 | 252 | 0.021 | |
| response to reactive oxygen species | GO:0000302 | 120 | 0.020 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.020 | |
| cellular metal ion homeostasis | GO:0006875 | 172 | 0.020 | |
| positive regulation of protein phosphorylation | GO:0001934 | 135 | 0.020 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.020 | |
| positive regulation of protein modification process | GO:0031401 | 142 | 0.020 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.019 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.019 | |
| defense response | GO:0006952 | 194 | 0.019 | |
| positive regulation of cell differentiation | GO:0045597 | 217 | 0.019 | |
| multi multicellular organism process | GO:0044706 | 138 | 0.019 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.019 | |
| calcium ion transport | GO:0006816 | 131 | 0.019 | |
| response to other organism | GO:0051707 | 220 | 0.019 | |
| negative regulation of developmental process | GO:0051093 | 125 | 0.019 | |
| response to external biotic stimulus | GO:0043207 | 221 | 0.019 | |
| response to inorganic substance | GO:0010035 | 377 | 0.019 | |
| signal transduction by phosphorylation | GO:0023014 | 144 | 0.019 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.019 | |
| cellular response to cytokine stimulus | GO:0071345 | 127 | 0.018 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.018 | |
| cation homeostasis | GO:0055080 | 195 | 0.018 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.018 | |
| negative regulation of transport | GO:0051051 | 136 | 0.018 | |
| central nervous system development | GO:0007417 | 311 | 0.018 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.018 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.018 | |
| regulation of secretion | GO:0051046 | 224 | 0.018 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.018 | |
| metal ion transport | GO:0030001 | 289 | 0.018 | |
| head development | GO:0060322 | 247 | 0.018 | |
| cyclic purine nucleotide metabolic process | GO:0052652 | 62 | 0.018 | |
| regulation of response to external stimulus | GO:0032101 | 106 | 0.018 | |
| regulation of ion transport | GO:0043269 | 245 | 0.018 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.018 | |
| peptide secretion | GO:0002790 | 86 | 0.017 | |
| negative regulation of signal transduction | GO:0009968 | 83 | 0.017 | |
| signal release | GO:0023061 | 145 | 0.017 | |
| regulation of molecular function | GO:0065009 | 398 | 0.017 | |
| cellular response to stress | GO:0033554 | 269 | 0.017 | |
| cation transport | GO:0006812 | 382 | 0.017 | |
| transcription dna templated | GO:0006351 | 377 | 0.017 | |
| regulation of peptide hormone secretion | GO:0090276 | 80 | 0.017 | |
| regulation of cytokine production | GO:0001817 | 56 | 0.017 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.017 | |
| reproduction | GO:0000003 | 245 | 0.017 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.016 | |
| regulation of cell development | GO:0060284 | 263 | 0.016 | |
| protein localization | GO:0008104 | 191 | 0.016 | |
| regulation of calcium ion transport | GO:0051924 | 77 | 0.016 | |
| establishment of protein localization | GO:0045184 | 141 | 0.016 | |
| myeloid leukocyte differentiation | GO:0002573 | 20 | 0.016 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.016 | |
| cellular response to external stimulus | GO:0071496 | 118 | 0.016 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.016 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.016 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.016 | |
| lipid metabolic process | GO:0006629 | 283 | 0.015 | |
| negative regulation of secretion by cell | GO:1903531 | 72 | 0.015 | |
| secretion by cell | GO:0032940 | 248 | 0.015 | |
| calcium ion homeostasis | GO:0055074 | 162 | 0.015 | |
| peptide hormone secretion | GO:0030072 | 84 | 0.015 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.015 | |
| rna metabolic process | GO:0016070 | 406 | 0.015 | |
| development of primary sexual characteristics | GO:0045137 | 107 | 0.015 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.015 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.014 | |
| telencephalon development | GO:0021537 | 62 | 0.014 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 4 | 0.014 | |
| ion homeostasis | GO:0050801 | 212 | 0.014 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.014 | |
| response to glucose | GO:0009749 | 136 | 0.014 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.014 | |
| regulation of hydrolase activity | GO:0051336 | 143 | 0.014 | |
| positive regulation of locomotion | GO:0040017 | 102 | 0.014 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.014 | |
| response to lipopolysaccharide | GO:0032496 | 191 | 0.014 | |
| actin filament based process | GO:0030029 | 86 | 0.014 | |
| positive regulation of cell development | GO:0010720 | 176 | 0.014 | |
| hormone transport | GO:0009914 | 121 | 0.014 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.014 | |
| cellular response to low density lipoprotein particle stimulus | GO:0071404 | 3 | 0.014 | |
| response to corticosteroid | GO:0031960 | 235 | 0.014 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.014 | |
| small molecule biosynthetic process | GO:0044283 | 124 | 0.014 | |
| circulatory system development | GO:0072359 | 134 | 0.014 | |
| multicellular organism growth | GO:0035264 | 1 | 0.014 | |
| regulation of insulin secretion | GO:0050796 | 65 | 0.014 | |
| regulation of protein transport | GO:0051223 | 68 | 0.014 | |
| neuron differentiation | GO:0030182 | 368 | 0.014 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.014 | |
| developmental induction | GO:0031128 | 2 | 0.014 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.013 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 140 | 0.013 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.013 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 37 | 0.013 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.013 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.013 | |
| carbohydrate metabolic process | GO:0005975 | 130 | 0.013 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.013 | |
| single organism cellular localization | GO:1902580 | 102 | 0.013 | |
| ras protein signal transduction | GO:0007265 | 29 | 0.013 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.013 | |
| response to transforming growth factor beta | GO:0071559 | 46 | 0.013 | |
| regulation of nucleotide metabolic process | GO:0006140 | 117 | 0.013 | |
| maintenance of location | GO:0051235 | 17 | 0.013 | |
| insulin secretion | GO:0030073 | 69 | 0.013 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.013 | |
| regulation of cell activation | GO:0050865 | 50 | 0.013 | |
| response to hexose | GO:0009746 | 144 | 0.013 | |
| regulation of defense response | GO:0031347 | 68 | 0.012 | |
| cellular carbohydrate metabolic process | GO:0044262 | 72 | 0.012 | |
| cytokine production | GO:0001816 | 61 | 0.012 | |
| lipid biosynthetic process | GO:0008610 | 128 | 0.012 | |
| cytoskeleton organization | GO:0007010 | 111 | 0.012 | |
| adenylate cyclase inhibiting g protein coupled receptor signaling pathway | GO:0007193 | 19 | 0.012 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.012 | |
| amide transport | GO:0042886 | 105 | 0.012 | |
| t cell homeostasis | GO:0043029 | 2 | 0.012 | |
| regulation of cell projection organization | GO:0031344 | 175 | 0.012 | |
| positive regulation of immune response | GO:0050778 | 42 | 0.012 | |
| defense response to gram negative bacterium | GO:0050829 | 3 | 0.012 | |
| negative regulation of natural killer cell mediated immunity | GO:0002716 | 4 | 0.012 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.012 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.012 | |
| ossification | GO:0001503 | 70 | 0.012 | |
| negative regulation of cell differentiation | GO:0045596 | 99 | 0.012 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.012 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.012 | |
| regulation of homeostatic process | GO:0032844 | 101 | 0.011 | |
| catabolic process | GO:0009056 | 351 | 0.011 | |
| positive regulation of secretion | GO:0051047 | 140 | 0.011 | |
| digestion | GO:0007586 | 26 | 0.011 | |
| negative regulation of hormone secretion | GO:0046888 | 46 | 0.011 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.011 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.011 | |
| regulation of ion transmembrane transport | GO:0034765 | 121 | 0.011 | |
| sequestering of metal ion | GO:0051238 | 9 | 0.011 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.011 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.011 | |
| regulation of leukocyte activation | GO:0002694 | 45 | 0.011 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.011 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.011 | |
| myeloid leukocyte activation | GO:0002274 | 36 | 0.011 | |
| regulation of catabolic process | GO:0009894 | 113 | 0.011 | |
| reproductive system development | GO:0061458 | 128 | 0.011 | |
| locomotion | GO:0040011 | 237 | 0.011 | |
| actin cytoskeleton organization | GO:0030036 | 73 | 0.011 | |
| mapk cascade | GO:0000165 | 140 | 0.011 | |
| response to peptide | GO:1901652 | 292 | 0.011 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.011 | |
| regulation of body fluid levels | GO:0050878 | 90 | 0.011 | |
| protein targeting | GO:0006605 | 61 | 0.011 | |
| calcium ion transport into cytosol | GO:0060402 | 38 | 0.011 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.011 | |
| regulation of catecholamine secretion | GO:0050433 | 32 | 0.011 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 141 | 0.011 | |
| embryonic skeletal system morphogenesis | GO:0048704 | 3 | 0.011 | |
| action potential | GO:0001508 | 54 | 0.011 | |
| epithelial cell proliferation | GO:0050673 | 54 | 0.011 | |
| cellular protein complex assembly | GO:0043623 | 44 | 0.011 | |
| spermatogenesis | GO:0007283 | 99 | 0.011 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.011 | |
| regulation of muscle tissue development | GO:1901861 | 25 | 0.011 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.011 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.010 | |
| peptide transport | GO:0015833 | 97 | 0.010 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.010 | |
| brain development | GO:0007420 | 247 | 0.010 | |
| localization of cell | GO:0051674 | 202 | 0.010 | |
| regulation of establishment of protein localization | GO:0070201 | 69 | 0.010 | |
| response to food | GO:0032094 | 27 | 0.010 | |
| cellular component movement | GO:0006928 | 248 | 0.010 | |
| aromatic amino acid family metabolic process | GO:0009072 | 9 | 0.010 | |
| transmission of nerve impulse | GO:0019226 | 42 | 0.010 | |