IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Crybg3

beta-gamma crystallin domain containing 3

(Aliases: RGD1305628)

Ensembl: ENSRNOG00000001687
Entrez: 288204
RGD: 1305628

Process Predictions
Disease Predictions

Crybg3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
positive regulation of transport	GO:0051050	245	0.148
reproductive process	GO:0022414	372	0.138
response to estrogen	GO:0043627	232	0.130
secretion by cell	GO:0032940	248	0.128
multicellular organism reproduction	GO:0032504	233	0.124
positive regulation of cell communication	GO:0010647	271	0.115
protein heterooligomerization	GO:0051291	89	0.106
positive regulation of multicellular organismal process	GO:0051240	387	0.106
regulation of hormone levels	GO:0010817	187	0.101
regulation of apoptotic process	GO:0042981	335	0.091
single organism reproductive process	GO:0044702	297	0.087
secretion	GO:0046903	307	0.085
hormone transport	GO:0009914	121	0.073
regulation of ion transport	GO:0043269	245	0.071
regulation of nucleic acid templated transcription	GO:1903506	380	0.069
positive regulation of nervous system development	GO:0051962	178	0.067
regulation of secretion	GO:0051046	224	0.067
protein phosphorylation	GO:0006468	345	0.066
response to inorganic substance	GO:0010035	377	0.063
regulation of cell proliferation	GO:0042127	359	0.058
positive regulation of developmental process	GO:0051094	283	0.058
aging	GO:0007568	241	0.053
reproduction	GO:0000003	245	0.047
multicellular organismal reproductive process	GO:0048609	233	0.046
neurological system process	GO:0050877	219	0.046
response to hypoxia	GO:0001666	231	0.045
ossification	GO:0001503	70	0.045
response to decreased oxygen levels	GO:0036293	237	0.045
blood vessel morphogenesis	GO:0048514	58	0.045
response to extracellular stimulus	GO:0009991	380	0.044
neuron death	GO:0070997	127	0.044
localization of cell	GO:0051674	202	0.043
nucleic acid templated transcription	GO:0097659	379	0.043
regulation of cell motility	GO:2000145	131	0.043
chemical homeostasis	GO:0048878	292	0.043
ion homeostasis	GO:0050801	212	0.043
cation transport	GO:0006812	382	0.042
negative regulation of long term synaptic potentiation	GO:1900272	1	0.042
negative regulation of chronic inflammatory response	GO:0002677	2	0.041
organic anion transport	GO:0015711	132	0.040
multi multicellular organism process	GO:0044706	138	0.040
response to wounding	GO:0009611	254	0.040
transcription from rna polymerase ii promoter	GO:0006366	252	0.039
apoptotic process	GO:0006915	381	0.039
positive regulation of cell proliferation	GO:0008284	249	0.038
cellular response to growth factor stimulus	GO:0071363	162	0.038
multi organism reproductive process	GO:0044703	262	0.038
cell cell signaling	GO:0007267	335	0.037
intracellular signal transduction	GO:0035556	314	0.036
response to nutrient levels	GO:0031667	370	0.036
response to external biotic stimulus	GO:0043207	221	0.036
response to growth factor	GO:0070848	189	0.035
defense response	GO:0006952	194	0.035
saliva secretion	GO:0046541	3	0.035
cellular ion homeostasis	GO:0006873	184	0.034
protein oligomerization	GO:0051259	191	0.034
action potential	GO:0001508	54	0.034
angioblast cell migration	GO:0035476	1	0.034
regulation of regulatory t cell differentiation	GO:0045589	2	0.033
regulation of protein metabolic process	GO:0051246	289	0.032
somatostatin receptor signaling pathway	GO:0038169	4	0.032
regulation of phosphorylation	GO:0042325	248	0.032
response to estradiol	GO:0032355	164	0.031
signal release	GO:0023061	145	0.031
neutrophil apoptotic process	GO:0001781	4	0.031
programmed cell death	GO:0012501	392	0.030
cellular component movement	GO:0006928	248	0.030
nitrogen compound transport	GO:0071705	229	0.030
response to bacterium	GO:0009617	200	0.030
hormone secretion	GO:0046879	115	0.029
regulation of transmembrane transport	GO:0034762	122	0.029
negative regulation of metabolic process	GO:0009892	331	0.028
ion transmembrane transport	GO:0034220	365	0.028
organic hydroxy compound metabolic process	GO:1901615	115	0.028
response to oxygen levels	GO:0070482	265	0.028
transmembrane transport	GO:0055085	412	0.027
tube development	GO:0035295	89	0.027
regulation of hormone secretion	GO:0046883	106	0.027
cellular response to endogenous stimulus	GO:0071495	377	0.027
regulation of cellular protein metabolic process	GO:0032268	267	0.027
response to peptide hormone	GO:0043434	278	0.027
organ regeneration	GO:0031100	101	0.026
forebrain development	GO:0030900	98	0.026
ovulation cycle	GO:0042698	67	0.026
cellular calcium ion homeostasis	GO:0006874	160	0.026
calcium ion homeostasis	GO:0055074	162	0.025
cellular component biogenesis	GO:0044085	368	0.025
brain development	GO:0007420	247	0.025
divalent inorganic cation homeostasis	GO:0072507	165	0.025
response to peptide	GO:1901652	292	0.025
positive regulation of protein metabolic process	GO:0051247	178	0.024
positive regulation of gene expression	GO:0010628	244	0.024
positive regulation of signaling	GO:0023056	270	0.024
positive regulation of secretion by cell	GO:1903532	128	0.024
acute inflammatory response	GO:0002526	58	0.024
regulation of multicellular organismal development	GO:2000026	376	0.024
positive regulation of rna metabolic process	GO:0051254	203	0.024
central nervous system development	GO:0007417	311	0.023
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.023
inorganic ion transmembrane transport	GO:0098660	229	0.023
regulation of cell differentiation	GO:0045595	320	0.023
negative regulation of gene expression	GO:0010629	199	0.023
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.023
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.023
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	51	0.023
negative regulation of secretion by cell	GO:1903531	72	0.023
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.023
rna metabolic process	GO:0016070	406	0.022
positive regulation of cell differentiation	GO:0045597	217	0.022
regulation of cellular localization	GO:0060341	263	0.022
positive regulation of cell development	GO:0010720	176	0.022
cellular cation homeostasis	GO:0030003	180	0.022
rna biosynthetic process	GO:0032774	380	0.022
positive regulation of programmed cell death	GO:0043068	157	0.022
wound healing	GO:0042060	122	0.022
negative regulation of apoptotic process	GO:0043066	181	0.022
regulation of programmed cell death	GO:0043067	341	0.021
erk1 and erk2 cascade	GO:0070371	48	0.021
regulation of cell development	GO:0060284	263	0.021
gland development	GO:0048732	155	0.021
positive regulation of neurogenesis	GO:0050769	165	0.021
muscle contraction	GO:0006936	88	0.021
sensory perception	GO:0007600	101	0.021
cation homeostasis	GO:0055080	195	0.021
chronic inflammatory response to non antigenic stimulus	GO:0002545	1	0.021
positive regulation of peptide secretion	GO:0002793	52	0.020
regulation of nervous system development	GO:0051960	264	0.020
female pregnancy	GO:0007565	122	0.020
g protein coupled receptor signaling pathway	GO:0007186	242	0.020
regulation of peptide hormone secretion	GO:0090276	80	0.020
anion transport	GO:0006820	178	0.020
homeostatic process	GO:0042592	331	0.020
adenylate cyclase inhibiting opioid receptor signaling pathway	GO:0031635	2	0.020
response to molecule of bacterial origin	GO:0002237	194	0.020
negative regulation of cell death	GO:0060548	229	0.020
regulation of saliva secretion	GO:0046877	3	0.020
response to toxic substance	GO:0009636	133	0.020
growth	GO:0040007	165	0.019
regulation of response to wounding	GO:1903034	69	0.019
cardiovascular system development	GO:0072358	134	0.019
transcription dna templated	GO:0006351	377	0.019
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.019
cellular response to organic cyclic compound	GO:0071407	202	0.019
gamete generation	GO:0007276	124	0.019
negative regulation of secretion	GO:0051048	82	0.019
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity	GO:2000311	11	0.018
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.018
oxoacid metabolic process	GO:0043436	290	0.018
positive regulation of hormone secretion	GO:0046887	65	0.018
negative regulation of biosynthetic process	GO:0009890	168	0.018
carboxylic acid transport	GO:0046942	115	0.018
tryptophan catabolic process	GO:0006569	5	0.018
cellular metal ion homeostasis	GO:0006875	172	0.018
organic acid metabolic process	GO:0006082	292	0.018
monovalent inorganic cation transport	GO:0015672	172	0.018
digestive system process	GO:0022600	24	0.018
positive regulation of biosynthetic process	GO:0009891	319	0.018
negative regulation of cellular metabolic process	GO:0031324	281	0.018
regulation of anion transport	GO:0044070	43	0.018
regulation of homeostatic process	GO:0032844	101	0.017
head development	GO:0060322	247	0.017
circulatory system process	GO:0003013	183	0.017
regulation of membrane potential	GO:0042391	110	0.017
metanephric tubule morphogenesis	GO:0072173	2	0.017
positive regulation of cellular protein metabolic process	GO:0032270	167	0.017
t cell tolerance induction	GO:0002517	3	0.017
blood circulation	GO:0008015	183	0.017
peptide hormone secretion	GO:0030072	84	0.017
negative regulation of response to stimulus	GO:0048585	155	0.017
response to lipopolysaccharide	GO:0032496	191	0.017
negative regulation of transport	GO:0051051	136	0.017
macromolecular complex subunit organization	GO:0043933	339	0.017
rhythmic process	GO:0048511	156	0.016
urinary bladder smooth muscle contraction	GO:0014832	4	0.016
regulation of neuron death	GO:1901214	115	0.016
response to histamine	GO:0034776	3	0.016
proteolysis	GO:0006508	175	0.016
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.016
somatostatin signaling pathway	GO:0038170	4	0.016
protein complex biogenesis	GO:0070271	263	0.016
positive regulation of apoptotic process	GO:0043065	154	0.016
peptide secretion	GO:0002790	86	0.016
calcium ion transport	GO:0006816	131	0.016
regulation of organic acid transport	GO:0032890	35	0.015
catabolic process	GO:0009056	351	0.015
vasculature development	GO:0001944	70	0.015
lipid metabolic process	GO:0006629	283	0.015
cellular chemical homeostasis	GO:0055082	247	0.015
response to alkaloid	GO:0043279	132	0.015
response to cytokine	GO:0034097	215	0.015
divalent inorganic cation transport	GO:0072511	134	0.015
cellular homeostasis	GO:0019725	252	0.015
response to interleukin 15	GO:0070672	4	0.015
regulation of rna metabolic process	GO:0051252	391	0.015
cell proliferation in forebrain	GO:0021846	3	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.015
regulation of blood circulation	GO:1903522	110	0.015
cell type specific apoptotic process	GO:0097285	134	0.015
response to mechanical stimulus	GO:0009612	134	0.015
cellular modified amino acid metabolic process	GO:0006575	61	0.015
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.015
cellular amine metabolic process	GO:0044106	38	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.015
positive regulation of response to stimulus	GO:0048584	285	0.014
cellular response to stress	GO:0033554	269	0.014
positive regulation of action potential	GO:0045760	8	0.014
g protein coupled purinergic nucleotide receptor signaling pathway	GO:0035589	3	0.014
peristalsis	GO:0030432	2	0.014
regulation of ion transmembrane transport	GO:0034765	121	0.014
inorganic cation transmembrane transport	GO:0098662	202	0.014
positive regulation of fat cell proliferation	GO:0070346	1	0.014
regulation of signal transduction	GO:0009966	318	0.014
amino acid transport	GO:0006865	70	0.014
negative regulation of macromolecule metabolic process	GO:0010605	260	0.014
positive regulation of intracellular signal transduction	GO:1902533	138	0.013
peptide transport	GO:0015833	97	0.013
regeneration	GO:0031099	163	0.013
regulation of receptor activity	GO:0010469	29	0.013
positive regulation of secretion	GO:0051047	140	0.013
negative regulation of programmed cell death	GO:0043069	183	0.013
positive regulation of transcription dna templated	GO:0045893	197	0.013
vesicle mediated transport	GO:0016192	181	0.013
regulatory t cell differentiation	GO:0045066	2	0.013
negative regulation of defecation	GO:2000293	1	0.013
response to ammonium ion	GO:0060359	71	0.013
anion transmembrane transport	GO:0098656	77	0.013
telencephalon development	GO:0021537	62	0.013
response to blue light	GO:0009637	1	0.013
positive regulation of cell death	GO:0010942	184	0.013
amine metabolic process	GO:0009308	38	0.013
negative regulation of amine transport	GO:0051953	24	0.013
negative regulation of neutrophil apoptotic process	GO:0033030	3	0.013
positive regulation of protein phosphorylation	GO:0001934	135	0.012
response to transition metal nanoparticle	GO:1990267	122	0.012
circadian sleep wake cycle wakefulness	GO:0042746	2	0.012
reproductive system development	GO:0061458	128	0.012
negative regulation of cell proliferation	GO:0008285	119	0.012
cellular response to cytokine stimulus	GO:0071345	127	0.012
sleep	GO:0030431	30	0.012
response to other organism	GO:0051707	220	0.012
regulation of response to external stimulus	GO:0032101	106	0.012
regulation of rna biosynthetic process	GO:2001141	381	0.012
cellular response to oxygen containing compound	GO:1901701	386	0.012
cell migration	GO:0016477	197	0.012
neural precursor cell proliferation	GO:0061351	23	0.012
regulation of defense response	GO:0031347	68	0.012
positive regulation of phosphorylation	GO:0042327	177	0.012
immune system process	GO:0002376	204	0.012
regulation of molecular function	GO:0065009	398	0.012
cellular response to histamine	GO:0071420	3	0.011
developmental process involved in reproduction	GO:0003006	159	0.011
macromolecular complex assembly	GO:0065003	273	0.011
positive regulation of signal transduction	GO:0009967	175	0.011
carboxylic acid metabolic process	GO:0019752	289	0.011
male gamete generation	GO:0048232	99	0.011
inflammatory response	GO:0006954	150	0.011
metal ion transport	GO:0030001	289	0.011
behavior	GO:0007610	205	0.011
positive regulation of blood circulation	GO:1903524	65	0.011
negative regulation of cell communication	GO:0010648	158	0.011
regulation of cellular ketone metabolic process	GO:0010565	27	0.011
response to radiation	GO:0009314	137	0.011
positive regulation of leukocyte apoptotic process	GO:2000108	1	0.011
cation transmembrane transport	GO:0098655	263	0.011
regulation of cellular amine metabolic process	GO:0033238	8	0.011
copulation	GO:0007620	17	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.011
tumor necrosis factor biosynthetic process	GO:0042533	1	0.011
regulation of phosphorus metabolic process	GO:0051174	349	0.011
negative regulation of catalytic activity	GO:0043086	103	0.011
negative regulation of chronic inflammatory response to non antigenic stimulus	GO:0002881	1	0.010
regulation of secretion by cell	GO:1903530	208	0.010
response to hexose	GO:0009746	144	0.010
synaptic transmission gabaergic	GO:0051932	22	0.010
cellular response to external stimulus	GO:0071496	118	0.010
positive regulation of cellular biosynthetic process	GO:0031328	295	0.010
metal ion homeostasis	GO:0055065	186	0.010
positive regulation of leukocyte activation	GO:0002696	30	0.010
vascular process in circulatory system	GO:0003018	96	0.010
organelle organization	GO:0006996	266	0.010
positive regulation of saliva secretion	GO:0046878	3	0.010
response to acid chemical	GO:0001101	222	0.010
metanephric epithelium development	GO:0072207	4	0.010

Crybg3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of mental health	DOID:150	0.016
substance related disorder	DOID:303	0.016
sensory system disease	DOID:0050155	0.012
eye disease	DOID:5614	0.012
blindness	DOID:1432	0.012
disease of anatomical entity	DOID:7	0.012
retinal disease	DOID:5679	0.012
nervous system disease	DOID:863	0.012
eye and adnexa disease	DOID:1492	0.012
integumentary system disease	DOID:16	0.010

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