Rattus norvegicus

0 known processes

Plk4

polo-like kinase 4 (Drosophila)

Plk4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein localization to chromosome centromeric regionGO:007145910.090
cellular component biogenesisGO:00440853680.088
Human Mouse Fly
cellular component assemblyGO:00226073600.086
Human Mouse Fly
protein complex biogenesisGO:00702712630.065
multi organism reproductive processGO:00447032620.060
Fly
regulation of multicellular organismal developmentGO:20000263760.058
cellular component movementGO:00069282480.057
reproductionGO:00000032450.056
Fly
macromolecule localizationGO:00330362520.054
single organism reproductive processGO:00447022970.054
Mouse Fly
regulation of molecular functionGO:00650093980.053
regulation of cell developmentGO:00602842630.053
development of primary sexual characteristicsGO:00451371070.053
negative regulation of metabolic processGO:00098923310.052
reproductive structure developmentGO:00486081280.052
Mouse
multicellular organism reproductionGO:00325042330.051
Fly
reproductive system developmentGO:00614581280.046
Mouse
cellular response to stressGO:00335542690.045
programmed cell deathGO:00125013920.045
protein complex subunit organizationGO:00718223020.045
Fly
single organism organelle organizationGO:19025891800.044
Human Mouse Fly
multicellular organismal reproductive processGO:00486092330.043
Fly
reproductive processGO:00224143720.043
Mouse Fly
negative regulation of cellular metabolic processGO:00313242810.042
regulation of transcription dna templatedGO:00063553740.042
gonad developmentGO:00084061040.042
protein complex assemblyGO:00064612630.041
regulation of cell differentiationGO:00455953200.041
agingGO:00075682410.040
anatomical structure morphogenesisGO:00096532980.039
Fly
developmental process involved in reproductionGO:00030061590.039
Mouse Fly
double strand break repairGO:000630210.039
cell motilityGO:00488702020.038
response to estradiolGO:00323551640.036
response to estrogenGO:00436272320.036
transcription dna templatedGO:00063513770.033
negative regulation of macromolecule metabolic processGO:00106052600.033
negative regulation of gene expressionGO:00106291990.033
regulation of neurogenesisGO:00507672470.033
regulation of apoptotic processGO:00429813350.033
rna biosynthetic processGO:00327743800.032
regulation of rna biosynthetic processGO:20011413810.032
negative regulation of cellular component organizationGO:0051129830.032
cellular response to oxygen containing compoundGO:19017013860.032
response to corticosteroidGO:00319602350.031
response to radiationGO:00093141370.031
transcription from rna polymerase ii promoterGO:00063662520.030
rna metabolic processGO:00160704060.030
neuron differentiationGO:00301823680.030
response to oxygen levelsGO:00704822650.030
intracellular transportGO:00469071850.029
positive regulation of cellular biosynthetic processGO:00313282950.029
positive regulation of cell proliferationGO:00082842490.029
regulation of cellular protein metabolic processGO:00322682670.028
cellular amine metabolic processGO:0044106380.028
organic substance catabolic processGO:19015753160.028
Fly
sex differentiationGO:00075481130.028
response to peptideGO:19016522920.027
central nervous system developmentGO:00074173110.027
response to peptide hormoneGO:00434342780.026
regulation of rna metabolic processGO:00512523910.026
regulation of cellular component organizationGO:00511283680.026
Human Fly
chromosome segregationGO:000705920.025
negative regulation of mitotic cell cycle phase transitionGO:190199130.025
rhythmic processGO:00485111560.025
cell cycle checkpointGO:000007520.025
protein phosphorylationGO:00064683450.024
Human Mouse Fly
response to nutrientGO:00075842480.024
carboxylic acid metabolic processGO:00197522890.024
histone serine phosphorylationGO:003540410.023
regulation of nervous system developmentGO:00519602640.023
response to ketoneGO:19016541820.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
negative regulation of cellular biosynthetic processGO:00313271610.023
regulation of nucleic acid templated transcriptionGO:19035063800.023
macromolecular complex subunit organizationGO:00439333390.023
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
apoptotic processGO:00069153810.022
oxoacid metabolic processGO:00434362900.022
response to other organismGO:00517072200.022
positive regulation of multicellular organismal processGO:00512403870.022
cell cycleGO:00070491010.022
Human Mouse Fly
brain developmentGO:00074202470.022
regulation of catalytic activityGO:00507903040.021
positive regulation of biosynthetic processGO:00098913190.021
response to metal ionGO:00100382530.021
positive regulation of developmental processGO:00510942830.021
response to extracellular stimulusGO:00099913800.021
carbohydrate derivative metabolic processGO:19011353460.021
positive regulation of molecular functionGO:00440932300.021
gamete generationGO:00072761240.021
Fly
response to ethanolGO:00454711620.020
negative regulation of cell deathGO:00605482290.020
negative regulation of biosynthetic processGO:00098901680.020
regenerationGO:00310991630.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
regulation of proteasomal protein catabolic processGO:006113640.020
cellular amino acid metabolic processGO:00065201070.020
cellular ketone metabolic processGO:0042180510.019
negative regulation of macromolecule biosynthetic processGO:00105581480.019
metaphase anaphase transition of cell cycleGO:004478410.019
asymmetric protein localizationGO:000810520.019
positive regulation of nervous system developmentGO:00519621780.019
organic acid metabolic processGO:00060822920.018
response to inorganic substanceGO:00100353770.018
response to acid chemicalGO:00011012220.018
dna metabolic processGO:0006259960.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
dna packagingGO:000632340.018
sexual reproductionGO:00199531480.018
Fly
positive regulation of cell differentiationGO:00455972170.017
regulation of signal transductionGO:00099663180.017
regulation of cellular ketone metabolic processGO:0010565270.017
response to glucocorticoidGO:00513842230.017
organelle organizationGO:00069962660.017
Human Mouse Fly
response to hypoxiaGO:00016662310.017
regulation of cellular amine metabolic processGO:003323880.017
cell projection organizationGO:00300303020.017
Fly
growthGO:00400071650.017
negative regulation of programmed cell deathGO:00430691830.017
regulation of protein metabolic processGO:00512462890.016
Fly
spermatogenesisGO:0007283990.016
Fly
negative regulation of chromosome organizationGO:200125110.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
metaphase anaphase transition of mitotic cell cycleGO:000709110.016
regulation of programmed cell deathGO:00430673410.016
amine metabolic processGO:0009308380.016
positive regulation of gene expressionGO:00106282440.016
protein oligomerizationGO:00512591910.016
head developmentGO:00603222470.016
macromolecular complex assemblyGO:00650032730.016
regulation of cell proliferationGO:00421273590.016
positive regulation of cellular component organizationGO:00511302000.015
Human
neuron developmentGO:00486662860.015
cytoskeleton organizationGO:00070101110.015
Human Mouse Fly
chemical homeostasisGO:00488782920.015
nucleic acid templated transcriptionGO:00976593790.015
cellular response to endogenous stimulusGO:00714953770.015
negative regulation of cell cycle phase transitionGO:190198840.015
cerebellar cortex morphogenesisGO:002169620.015
cerebellar cortex formationGO:002169720.015
response to molecule of bacterial originGO:00022371940.015
regulation of cellular amino acid metabolic processGO:000652120.015
cell cell signalingGO:00072673350.015
regulation of protein localizationGO:0032880810.014
response to external biotic stimulusGO:00432072210.014
positive regulation of transportGO:00510502450.014
locomotionGO:00400112370.014
response to decreased oxygen levelsGO:00362932370.014
cellular response to lipidGO:00713962010.014
regulation of protein modification processGO:00313991940.014
cellular response to organonitrogen compoundGO:00714171970.014
development of primary female sexual characteristicsGO:0046545560.014
male gamete generationGO:0048232990.014
Fly
negative regulation of rna biosynthetic processGO:19026791180.014
localization of cellGO:00516742020.014
intracellular signal transductionGO:00355563140.014
negative regulation of molecular functionGO:00440921330.013
positive regulation of catalytic activityGO:00430851840.013
response to nutrient levelsGO:00316673700.013
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.013
regulation of neuron differentiationGO:00456642080.013
response to vitaminGO:00332731310.013
positive regulation of signalingGO:00230562700.013
hindbrain morphogenesisGO:002157520.013
purine ribonucleotide catabolic processGO:00091541360.013
ovulation cycle processGO:0022602500.013
cellular response to organic cyclic compoundGO:00714072020.013
regulation of homeostatic processGO:00328441010.013
cellular cation homeostasisGO:00300031800.013
positive regulation of cell communicationGO:00106472710.013
positive regulation of cellular amine metabolic processGO:003324030.013
positive regulation of protein phosphorylationGO:00019341350.013
cell migrationGO:00164771970.013
cell growthGO:00160491040.013
neurological system processGO:00508772190.013
regulation of cell projection organizationGO:00313441750.013
positive regulation of nitrogen compound metabolic processGO:00511733340.013
response to cytokineGO:00340972150.013
regulation of microtubule based processGO:0032886140.013
Human Fly
negative regulation of transcription dna templatedGO:00458921160.013
cellular macromolecule localizationGO:00707271220.013
peptidyl amino acid modificationGO:00181931260.013
cellular ion homeostasisGO:00068731840.012
g protein coupled receptor signaling pathwayGO:00071862420.012
developmental growthGO:00485891000.012
triglyceride catabolic processGO:001943330.012
nucleotide metabolic processGO:00091172790.012
heterocycle catabolic processGO:00467001670.012
regulation of phosphorus metabolic processGO:00511743490.012
cellular response to hormone stimulusGO:00328702470.012
behaviorGO:00076102050.012
regulation of chromosome segregationGO:005198310.012
cell cycle dna replicationGO:004478610.012
positive regulation of rna metabolic processGO:00512542030.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
cellular lipid metabolic processGO:00442552080.012
negative regulation of protein metabolic processGO:00512481140.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
Fly
nucleobase containing compound catabolic processGO:00346551520.012
cellular response to external stimulusGO:00714961180.012
negative regulation of apoptotic processGO:00430661810.012
cerebellar purkinje cell layer morphogenesisGO:002169210.012
cerebellum morphogenesisGO:002158720.012
cerebellar purkinje cell layer developmentGO:002168020.012
positive regulation of neuron differentiationGO:00456661260.012
nucleosome organizationGO:003472810.012
regulation of cellular localizationGO:00603412630.012
positive regulation of phosphorylationGO:00423271770.011
regulation of cellular catabolic processGO:00313291010.011
positive regulation of neurogenesisGO:00507691650.011
organophosphate metabolic processGO:00196373700.011
regulation of neuron projection developmentGO:00109751610.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
ion transmembrane transportGO:00342203650.011
response to purine containing compoundGO:00140741260.011
ovulation cycleGO:0042698670.011
negative regulation of cell communicationGO:00106481580.011
circulatory system processGO:00030131830.011
female sex differentiationGO:0046660590.011
nucleobase containing small molecule metabolic processGO:00550863160.011
mitotic cell cycle checkpointGO:000709310.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
response to insulinGO:00328681330.011
dna recombinationGO:000631030.011
regulation of growthGO:00400081050.011
defense responseGO:00069521940.011
cellular homeostasisGO:00197252520.011
response to lipopolysaccharideGO:00324961910.011
cytoplasmic transportGO:00164821150.011
positive regulation of response to stimulusGO:00485842850.011
cellular process involved in reproduction in multicellular organismGO:0022412350.011
Fly
regulation of phosphorylationGO:00423252480.011
organophosphate catabolic processGO:00464341480.011
microtubule cytoskeleton organizationGO:0000226250.011
Human Mouse Fly
neuron deathGO:00709971270.011
regulation of intracellular signal transductionGO:19025312180.010
regulation of sister chromatid segregationGO:003304510.010
oxidation reduction processGO:00551143040.010
organonitrogen compound catabolic processGO:19015651790.010
positive regulation of rna biosynthetic processGO:19026801970.010
homeostatic processGO:00425923310.010
nucleoside phosphate metabolic processGO:00067532830.010
positive regulation of protein metabolic processGO:00512471780.010
Fly
regulation of mitotic sister chromatid segregationGO:003304710.010
catabolic processGO:00090563510.010
Fly
ion homeostasisGO:00508012120.010
proteolysisGO:00065081750.010
negative regulation of cellular protein metabolic processGO:00322691060.010
cellular response to abiotic stimulusGO:0071214850.010

Plk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.014
disease of anatomical entityDOID:700.014