Rattus norvegicus

5 known processes

Igfbp4

insulin-like growth factor binding protein 4

(Aliases: IGF-BP4,IBP4)

Igfbp4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nutrient levelsGO:00316673700.181
Rat
cellular response to hormone stimulusGO:00328702470.179
Rat
rna biosynthetic processGO:00327743800.139
response to extracellular stimulusGO:00099913800.129
Rat
regulation of rna biosynthetic processGO:20011413810.099
reproductive processGO:00224143720.097
Rat
cell motilityGO:00488702020.091
cellular component movementGO:00069282480.089
skeletal system developmentGO:0001501410.082
regulation of signal transductionGO:00099663180.082
Mouse
carboxylic acid metabolic processGO:00197522890.079
catabolic processGO:00090563510.075
regulation of nucleic acid templated transcriptionGO:19035063800.073
organic acid metabolic processGO:00060822920.072
regulation of phosphorylationGO:00423252480.072
Mouse
response to nutrientGO:00075842480.072
Rat
intracellular signal transductionGO:00355563140.069
Mouse Rat
transcription dna templatedGO:00063513770.068
cellular response to stressGO:00335542690.068
negative regulation of metabolic processGO:00098923310.067
regulation of multicellular organismal developmentGO:20000263760.067
response to ketoneGO:19016541820.066
oxoacid metabolic processGO:00434362900.066
response to corticosteroidGO:00319602350.065
Rat
cellular response to endogenous stimulusGO:00714953770.063
Rat
regulation of rna metabolic processGO:00512523910.062
regulation of transcription dna templatedGO:00063553740.062
tissue developmentGO:00098882520.061
Rat
positive regulation of nucleic acid templated transcriptionGO:19035081970.060
cellular response to oxygen containing compoundGO:19017013860.059
Rat
positive regulation of response to stimulusGO:00485842850.059
Mouse
positive regulation of developmental processGO:00510942830.058
regulation of transcription from rna polymerase ii promoterGO:00063572340.055
rna metabolic processGO:00160704060.053
positive regulation of macromolecule biosynthetic processGO:00105572470.051
regulation of response to stressGO:00801341260.050
regulation of phosphate metabolic processGO:00192203490.049
Mouse
anatomical structure morphogenesisGO:00096532980.048
positive regulation of cell communicationGO:00106472710.048
Mouse
nucleic acid templated transcriptionGO:00976593790.047
organic substance catabolic processGO:19015753160.047
regulation of phosphorus metabolic processGO:00511743490.046
Mouse
locomotionGO:00400112370.046
positive regulation of nitrogen compound metabolic processGO:00511733340.044
macromolecule localizationGO:00330362520.043
anterior posterior pattern specificationGO:000995210.043
regulation of protein modification processGO:00313991940.043
response to growth factorGO:00708481890.042
negative regulation of cellular metabolic processGO:00313242810.042
positive regulation of nucleobase containing compound metabolic processGO:00459353190.042
response to acid chemicalGO:00011012220.042
Rat
negative regulation of macromolecule metabolic processGO:00106052600.041
positive regulation of biosynthetic processGO:00098913190.041
regulation of intracellular signal transductionGO:19025312180.041
Mouse
response to monosaccharideGO:00342841590.041
negative regulation of gene expressionGO:00106291990.040
response to biotic stimulusGO:00096072260.040
regulation of apoptotic processGO:00429813350.040
single organism reproductive processGO:00447022970.040
response to inorganic substanceGO:00100353770.039
Rat
regulation of catalytic activityGO:00507903040.039
cellular amino acid metabolic processGO:00065201070.039
response to carbohydrateGO:00097431830.039
cellular response to external stimulusGO:00714961180.038
localization of cellGO:00516742020.038
transcription from rna polymerase ii promoterGO:00063662520.038
brain developmentGO:00074202470.037
positive regulation of cellular biosynthetic processGO:00313282950.037
positive regulation of rna biosynthetic processGO:19026801970.036
regulation of anatomical structure morphogenesisGO:00226031410.036
enzyme linked receptor protein signaling pathwayGO:00071671160.036
Mouse Rat
regulation of molecular functionGO:00650093980.035
cellular response to organic cyclic compoundGO:00714072020.035
positive regulation of multicellular organismal processGO:00512403870.034
cellular response to growth factor stimulusGO:00713631620.034
negative regulation of multicellular organismal processGO:00512412030.034
amine metabolic processGO:0009308380.034
renal system developmentGO:0072001670.033
homeostatic processGO:00425923310.033
ossificationGO:0001503700.033
vasculature developmentGO:0001944700.033
secretionGO:00469033070.032
positive regulation of phosphate metabolic processGO:00459372620.032
Mouse
regulation of cell motilityGO:20001451310.032
central nervous system developmentGO:00074173110.032
nucleotide metabolic processGO:00091172790.032
immune system processGO:00023762040.032
anion transportGO:00068201780.031
regulation of cellular localizationGO:00603412630.031
positive regulation of gene expressionGO:00106282440.031
regulation of cellular component organizationGO:00511283680.031
Mouse Rat
circulatory system developmentGO:00723591340.030
regulation of cellular amine metabolic processGO:003323880.030
response to cytokineGO:00340972150.030
positive regulation of cell deathGO:00109421840.030
kidney developmentGO:0001822670.029
embryonic skeletal system developmentGO:004870630.029
cellular response to organonitrogen compoundGO:00714171970.029
Rat
regulation of cellular protein metabolic processGO:00322682670.029
regulation of cellular ketone metabolic processGO:0010565270.029
single organism catabolic processGO:00447122830.028
rhythmic processGO:00485111560.028
regulation of cell migrationGO:00303341280.028
positive regulation of rna metabolic processGO:00512542030.028
multi multicellular organism processGO:00447061380.027
Rat
secretion by cellGO:00329402480.027
response to oxygen levelsGO:00704822650.027
nucleobase containing small molecule metabolic processGO:00550863160.027
positive regulation of cell proliferationGO:00082842490.027
regulation of programmed cell deathGO:00430673410.027
protein phosphorylationGO:00064683450.027
regulation of cellular amino acid metabolic processGO:000652120.026
ribose phosphate metabolic processGO:00196932350.026
regenerationGO:00310991630.026
Rat
ion transmembrane transportGO:00342203650.026
positive regulation of transportGO:00510502450.026
negative regulation of cellular biosynthetic processGO:00313271610.026
response to estradiolGO:00323551640.025
Rat
negative regulation of cell communicationGO:00106481580.025
positive regulation of phosphorus metabolic processGO:00105622620.025
Mouse
blood vessel developmentGO:0001568690.025
cardiovascular system developmentGO:00723581340.025
cellular catabolic processGO:00442482950.024
regulation of cell proliferationGO:00421273590.024
cellular component biogenesisGO:00440853680.024
response to peptideGO:19016522920.024
Rat
organic anion transportGO:00157111320.024
neuron developmentGO:00486662860.023
multicellular organism reproductionGO:00325042330.023
female pregnancyGO:00075651220.023
Rat
response to lipopolysaccharideGO:00324961910.023
programmed cell deathGO:00125013920.023
agingGO:00075682410.023
Rat
nucleoside phosphate metabolic processGO:00067532830.023
cellular response to cytokine stimulusGO:00713451270.023
response to glucoseGO:00097491360.023
cell growthGO:00160491040.023
Mouse Rat
carbohydrate metabolic processGO:00059751300.023
Mouse
protein localizationGO:00081041910.023
organophosphate metabolic processGO:00196373700.022
non canonical wnt signaling pathwayGO:003556730.022
positive regulation of programmed cell deathGO:00430681570.022
cell cell signalingGO:00072673350.022
response to woundingGO:00096112540.022
Rat
cellular component assemblyGO:00226073600.022
positive regulation of neuron projection developmentGO:0010976990.022
proteolysisGO:00065081750.021
response to hexoseGO:00097461440.021
carbohydrate derivative metabolic processGO:19011353460.021
positive regulation of cell differentiationGO:00455972170.021
small molecule catabolic processGO:0044282590.021
cellular protein localizationGO:00346131220.021
protein complex assemblyGO:00064612630.021
blood vessel morphogenesisGO:0048514580.021
positive regulation of cell projection organizationGO:00313461110.021
macromolecular complex assemblyGO:00650032730.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
regulation of protein metabolic processGO:00512462890.021
response to metal ionGO:00100382530.020
Rat
mesenchymal cell proliferationGO:001046340.020
monosaccharide metabolic processGO:0005996610.020
Mouse
positive regulation of nervous system developmentGO:00519621780.020
macromolecular complex subunit organizationGO:00439333390.020
response to vitaminGO:00332731310.020
regulation of neuron projection developmentGO:00109751610.020
cellular response to extracellular stimulusGO:0031668730.020
cellular response to nitrogen compoundGO:19016992100.020
Rat
response to glucocorticoidGO:00513842230.020
Rat
cell migrationGO:00164771970.020
negative regulation of protein metabolic processGO:00512481140.020
regulation of locomotionGO:00400121480.019
protein oligomerizationGO:00512591910.019
organonitrogen compound catabolic processGO:19015651790.019
single organism carbohydrate metabolic processGO:00447231180.019
Mouse
regulation of neuron deathGO:19012141150.019
chemical homeostasisGO:00488782920.019
carboxylic acid catabolic processGO:0046395490.019
cellular response to steroid hormone stimulusGO:0071383930.019
cellular ketone metabolic processGO:0042180510.019
positive regulation of cellular amine metabolic processGO:003324030.019
multi organism reproductive processGO:00447032620.019
Rat
positive regulation of protein phosphorylationGO:00019341350.019
female sex differentiationGO:0046660590.019
positive regulation of protein transportGO:0051222410.019
protein complex subunit organizationGO:00718223020.019
regulation of canonical wnt signaling pathwayGO:006082840.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.019
Mouse Rat
insulin like growth factor receptor signaling pathwayGO:004800930.019
Mouse
positive regulation of cell migrationGO:0030335960.019
cellular response to peptideGO:19016531330.018
Rat
reproductionGO:00000032450.018
negative regulation of signalingGO:00230571570.018
intracellular transportGO:00469071850.018
neuron projection developmentGO:00311752730.018
behaviorGO:00076102050.018
positive regulation of apoptotic processGO:00430651540.018
response to decreased oxygen levelsGO:00362932370.018
negative regulation of biosynthetic processGO:00098901680.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
regulation of transferase activityGO:00513381230.018
regulation of secretionGO:00510462240.017
neuron differentiationGO:00301823680.017
response to transforming growth factor betaGO:0071559460.017
positive regulation of cell motilityGO:2000147970.017
ribonucleotide metabolic processGO:00092592310.017
growthGO:00400071650.017
Mouse Rat
cellular chemical homeostasisGO:00550822470.017
mapk cascadeGO:00001651400.017
Mouse
regulation of mapk cascadeGO:00434081160.017
Mouse
regulation of odontogenesis of dentin containing toothGO:004248720.017
positive regulation of cellular component organizationGO:00511302000.017
cellular carbohydrate metabolic processGO:0044262720.017
Mouse
cellular amine metabolic processGO:0044106380.017
positive regulation of molecular functionGO:00440932300.017
regulation of protein phosphorylationGO:00019321830.017
cellular nitrogen compound catabolic processGO:00442701630.017
response to molecule of bacterial originGO:00022371940.017
regulation of cell developmentGO:00602842630.017
response to peptide hormoneGO:00434342780.016
Rat
purine ribonucleotide metabolic processGO:00091502270.016
regulation of establishment of planar polarityGO:009017520.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
ribonucleoside metabolic processGO:00091191740.016
endocytosisGO:0006897840.016
multicellular organismal reproductive processGO:00486092330.016
regulation of growthGO:00400081050.016
Mouse Rat
nitrogen compound transportGO:00717052290.016
protein complex biogenesisGO:00702712630.016
regulation of secretion by cellGO:19035302080.016
purine nucleoside metabolic processGO:00422781690.016
regulation of hormone levelsGO:00108171870.016
cellular response to nutrient levelsGO:0031669600.016
regulation of anatomical structure sizeGO:00900661350.016
positive regulation of ion transportGO:0043270940.016
purine nucleotide metabolic processGO:00061632290.016
gland developmentGO:00487321550.016
positive regulation of cell developmentGO:00107201760.016
establishment of tissue polarityGO:000716420.016
apoptotic processGO:00069153810.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
negative regulation of cell deathGO:00605482290.016
ovulation cycleGO:0042698670.016
divalent inorganic cation transportGO:00725111340.015
response to other organismGO:00517072200.015
cellular macromolecule localizationGO:00707271220.015
single organism biosynthetic processGO:00447113420.015
regulation of stem cell differentiationGO:200073620.015
positive regulation of phosphorylationGO:00423271770.015
Mouse
small gtpase mediated signal transductionGO:0007264360.015
wnt signaling pathway planar cell polarity pathwayGO:006007120.015
organic acid transportGO:00158491160.015
lipid metabolic processGO:00066292830.015
single organism intracellular transportGO:19025821660.015
embryonic skeletal system morphogenesisGO:004870430.015
monocarboxylic acid metabolic processGO:00327871520.015
response to oxidative stressGO:00069791860.015
glycosyl compound metabolic processGO:19016571820.015
negative regulation of response to stimulusGO:00485851550.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
ras protein signal transductionGO:0007265290.015
protein maturationGO:0051604680.015
response to temperature stimulusGO:0009266940.015
cellular response to insulin stimulusGO:0032869810.015
Rat
gastrulationGO:000736920.015
regulation of cell differentiationGO:00455953200.014
negative regulation of phosphate metabolic processGO:0045936800.014
regulation of fat cell differentiationGO:004559830.014
organic cyclic compound catabolic processGO:19013611750.014
negative regulation of fibrinolysisGO:005191820.014
purine ribonucleoside metabolic processGO:00461281680.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
cellular response to acid chemicalGO:0071229750.014
cellular response to alcoholGO:0097306870.014
cell projection organizationGO:00300303020.014
adult locomotory behaviorGO:000834440.014
cellular response to peptide hormone stimulusGO:00713751200.014
Rat
cell adhesionGO:00071551100.014
regulation of response to external stimulusGO:00321011060.014
response to heatGO:0009408600.014
positive regulation of signal transductionGO:00099671750.014
Mouse
regulation of mesenchymal cell proliferationGO:001046440.014
lipid transportGO:0006869610.014
cation transportGO:00068123820.014
carboxylic acid transportGO:00469421150.014
regulation of cellular response to growth factor stimulusGO:0090287150.014
regulation of protein transportGO:0051223680.014
signal transduction by phosphorylationGO:00230141440.014
Mouse
urogenital system developmentGO:0001655780.014
oxidation reduction processGO:00551143040.014
regulation of body fluid levelsGO:0050878900.013
gamete generationGO:00072761240.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
protein transportGO:00150311320.013
nucleoside phosphate catabolic processGO:19012921400.013
positive regulation of protein metabolic processGO:00512471780.013
regulation of cellular component movementGO:00512701500.013
vesicle mediated transportGO:00161921810.013
response to estrogenGO:00436272320.013
Rat
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
heterocycle catabolic processGO:00467001670.013
cell cell signaling involved in cell fate commitmentGO:004516820.013
multicellular organism growthGO:003526410.013
vascular process in circulatory systemGO:0003018960.013
peptidyl amino acid modificationGO:00181931260.013
transmembrane transportGO:00550854120.013
positive regulation of neuron differentiationGO:00456661260.013
neuron deathGO:00709971270.013
single organism behaviorGO:00447081300.013
positive regulation of protein modification processGO:00314011420.013
wound healingGO:00420601220.013
Rat
regulation of cellular component biogenesisGO:0044087860.013
hexose metabolic processGO:0019318580.012
Mouse
regulation of cell growthGO:0001558850.012
Mouse Rat
nucleoside triphosphate metabolic processGO:00091411440.012
eye morphogenesisGO:004859240.012
regulation of cell projection organizationGO:00313441750.012
anion transmembrane transportGO:0098656770.012
positive regulation of intracellular signal transductionGO:19025331380.012
Mouse
cellular response to transforming growth factor beta stimulusGO:0071560410.012
nucleoside catabolic processGO:00091641260.012
response to retinoic acidGO:0032526630.012
Rat
positive regulation of signalingGO:00230562700.012
Mouse
regulation of protein localizationGO:0032880810.012
morphogenesis of a polarized epitheliumGO:000173810.012
purine ribonucleoside catabolic processGO:00461301240.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
neurological system processGO:00508772190.012
intracellular protein transportGO:0006886790.012
response to bacteriumGO:00096172000.012
appendage morphogenesisGO:003510740.012
response to alkaloidGO:00432791320.012
negative regulation of catalytic activityGO:00430861030.012
regulation of immune system processGO:00026821230.012
circulatory system processGO:00030131830.012
biological adhesionGO:00226101100.012
embryonic pattern specificationGO:000988010.012
reactive oxygen species metabolic processGO:0072593370.012
regulation of kinase activityGO:00435491170.011
response to mechanical stimulusGO:00096121340.011
Rat
positive regulation of catalytic activityGO:00430851840.011
development of primary female sexual characteristicsGO:0046545560.011
response to transition metal nanoparticleGO:19902671220.011
head developmentGO:00603222470.011
organonitrogen compound biosynthetic processGO:19015661670.011
negative regulation of developmental processGO:00510931250.011
nucleoside metabolic processGO:00091161790.011
connective tissue developmentGO:0061448330.011
response to interleukin 1GO:0070555550.011
heart morphogenesisGO:000300730.011
cellular response to lipidGO:00713962010.011
purine nucleotide catabolic processGO:00061951360.011
glucose metabolic processGO:0006006520.011
Mouse
embryonic cranial skeleton morphogenesisGO:004870120.011
regulation of cell sizeGO:0008361370.011
syncytium formation by plasma membrane fusionGO:000076830.011
cellular response to abiotic stimulusGO:0071214850.011
regulation of ion transportGO:00432692450.011
positive regulation of mesenchymal cell proliferationGO:000205340.010
negative regulation of phosphorus metabolic processGO:0010563800.010
ion homeostasisGO:00508012120.010
amino acid transportGO:0006865700.010
negative regulation of molecular functionGO:00440921330.010
regulation of reactive oxygen species metabolic processGO:2000377260.010
axis specificationGO:000979840.010
regulation of cellular response to stressGO:0080135490.010
smooth muscle cell proliferationGO:0048659770.010
regulation of defense responseGO:0031347680.010
blood circulationGO:00080151830.010
sexual reproductionGO:00199531480.010
tissue remodelingGO:0048771400.010
cellular cation homeostasisGO:00300031800.010
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.010
positive regulation of locomotionGO:00400171020.010
negative regulation of canonical wnt signaling pathwayGO:009009040.010

Igfbp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.018
bone diseaseDOID:008000100.018
connective tissue diseaseDOID:6500.018
disease of anatomical entityDOID:700.018
nervous system diseaseDOID:86300.015
bone development diseaseDOID:008000600.013
disease of metabolismDOID:001466700.013
central nervous system diseaseDOID:33100.011