IMP: Integrative Multi-species Prediction

Rattus norvegicus

204 known processes

Cdc42

cell division cycle 42 (GTP binding protein)

Ensembl: ENSRNOG00000013536
Entrez: 64465
RGD: 71043
UniProtKB: Q8CFN2

Process Predictions
Disease Predictions

Cdc42 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
apoptotic process	GO:0006915	381	0.623
programmed cell death	GO:0012501	392	0.549
negative regulation of cellular biosynthetic process	GO:0031327	161	0.432
cation transmembrane transport	GO:0098655	263	0.424
regulation of phosphorus metabolic process	GO:0051174	349	0.369
intracellular transport	GO:0046907	185	0.367
cellular response to insulin stimulus	GO:0032869	81	0.341
positive regulation of apoptotic process	GO:0043065	154	0.330
inorganic cation transmembrane transport	GO:0098662	202	0.313
macromolecular complex assembly	GO:0065003	273	0.308	Human Fly
regulation of apoptotic process	GO:0042981	335	0.306
cation transport	GO:0006812	382	0.306
intracellular signal transduction	GO:0035556	314	0.296
protein phosphorylation	GO:0006468	345	0.292	Mouse Fly
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.285
ribonucleotide metabolic process	GO:0009259	231	0.279	Mouse Rat Fly
organophosphate metabolic process	GO:0019637	370	0.257	Mouse Rat Fly
cellular response to peptide	GO:1901653	133	0.254
purine nucleoside catabolic process	GO:0006152	124	0.254	Mouse Rat Fly
regulation of molecular function	GO:0065009	398	0.248
rna biosynthetic process	GO:0032774	380	0.241
divalent metal ion transport	GO:0070838	132	0.239
regulation of nucleic acid templated transcription	GO:1903506	380	0.235
aromatic compound catabolic process	GO:0019439	168	0.231	Mouse Rat Fly
cellular response to nitrogen compound	GO:1901699	210	0.223
nucleoside catabolic process	GO:0009164	126	0.216	Mouse Rat Fly
regulation of protein phosphorylation	GO:0001932	183	0.212	Mouse Fly
positive regulation of molecular function	GO:0044093	230	0.210
positive regulation of protein metabolic process	GO:0051247	178	0.210	Mouse Fly
growth	GO:0040007	165	0.209	Mouse Fly
nucleobase containing small molecule metabolic process	GO:0055086	316	0.208	Mouse Rat Fly
metal ion transport	GO:0030001	289	0.207
ribonucleoside metabolic process	GO:0009119	174	0.204	Mouse Rat Fly
response to peptide hormone	GO:0043434	278	0.202
ion transmembrane transport	GO:0034220	365	0.200
positive regulation of developmental process	GO:0051094	283	0.198	Human
inorganic ion transmembrane transport	GO:0098660	229	0.198
regulation of cell cycle	GO:0051726	73	0.195	Human Mouse
regulation of programmed cell death	GO:0043067	341	0.195
regulation of transcription dna templated	GO:0006355	374	0.195
cellular macromolecule localization	GO:0070727	122	0.193
positive regulation of response to stimulus	GO:0048584	285	0.191
protein complex biogenesis	GO:0070271	263	0.185	Human Fly
organic substance catabolic process	GO:1901575	316	0.183	Mouse Rat Fly
nucleotide metabolic process	GO:0009117	279	0.175	Mouse Rat Fly
transmembrane transport	GO:0055085	412	0.172
regulation of catalytic activity	GO:0050790	304	0.172
nucleoside monophosphate catabolic process	GO:0009125	56	0.171
cell projection morphogenesis	GO:0048858	123	0.163	Fly
negative regulation of metabolic process	GO:0009892	331	0.162	Mouse
catabolic process	GO:0009056	351	0.161	Mouse Rat Fly
purine containing compound catabolic process	GO:0072523	138	0.160	Mouse Rat Fly
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.156
purine containing compound metabolic process	GO:0072521	253	0.153	Mouse Rat Fly
response to peptide	GO:1901652	292	0.151
positive regulation of cell death	GO:0010942	184	0.150
purine ribonucleotide metabolic process	GO:0009150	227	0.150	Mouse Rat Fly
nucleoside phosphate metabolic process	GO:0006753	283	0.147	Mouse Rat Fly
cellular component morphogenesis	GO:0032989	155	0.147	Human Fly
response to corticosteroid	GO:0031960	235	0.145
positive regulation of transport	GO:0051050	245	0.143
ribonucleotide catabolic process	GO:0009261	136	0.142	Mouse Rat Fly
positive regulation of cellular protein metabolic process	GO:0032270	167	0.141	Mouse Fly
response to acid chemical	GO:0001101	222	0.135
regulation of protein kinase activity	GO:0045859	105	0.132	Mouse Fly
cellular response to stress	GO:0033554	269	0.131
ribonucleoside monophosphate catabolic process	GO:0009158	55	0.131
transcription dna templated	GO:0006351	377	0.129
cellular response to endogenous stimulus	GO:0071495	377	0.128
macromolecule localization	GO:0033036	252	0.126
protein complex subunit organization	GO:0071822	302	0.126
regulation of ion transport	GO:0043269	245	0.125
glycosyl compound catabolic process	GO:1901658	126	0.125	Mouse Rat Fly
regulation of protein metabolic process	GO:0051246	289	0.122	Mouse Fly
positive regulation of cell differentiation	GO:0045597	217	0.122	Human
purine nucleotide metabolic process	GO:0006163	229	0.122	Mouse Rat Fly
regulation of rna biosynthetic process	GO:2001141	381	0.121
calcium ion transport	GO:0006816	131	0.120
regulation of rna metabolic process	GO:0051252	391	0.118
regulation of phosphorylation	GO:0042325	248	0.118
cellular catabolic process	GO:0044248	295	0.118	Mouse Rat Fly
cellular response to oxygen containing compound	GO:1901701	386	0.118
organelle organization	GO:0006996	266	0.118
negative regulation of biosynthetic process	GO:0009890	168	0.116
positive regulation of protein modification process	GO:0031401	142	0.113	Mouse Fly
ribose phosphate metabolic process	GO:0019693	235	0.111	Mouse Rat Fly
response to light stimulus	GO:0009416	52	0.111
regulation of phosphate metabolic process	GO:0019220	349	0.111
nucleoside monophosphate metabolic process	GO:0009123	93	0.111
purine ribonucleoside catabolic process	GO:0046130	124	0.111	Mouse Rat Fly
protein localization to organelle	GO:0033365	57	0.110
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.109
macromolecular complex subunit organization	GO:0043933	339	0.108
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.105	Mouse Rat Fly
ribonucleoside catabolic process	GO:0042454	126	0.104	Mouse Rat Fly
cellular component biogenesis	GO:0044085	368	0.104	Human Mouse Fly
negative regulation of cellular metabolic process	GO:0031324	281	0.103
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.103
establishment of protein localization	GO:0045184	141	0.102
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.098
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.098	Mouse Rat Fly
cell morphogenesis involved in differentiation	GO:0000904	119	0.096	Human Fly
response to insulin	GO:0032868	133	0.095
regulation of actin cytoskeleton organization	GO:0032956	30	0.095	Fly
carbohydrate derivative metabolic process	GO:1901135	346	0.094	Mouse Rat Fly
positive regulation of multicellular organismal process	GO:0051240	387	0.093
regulation of cell proliferation	GO:0042127	359	0.093	Mouse
single organism intracellular transport	GO:1902582	166	0.093
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.092
anatomical structure morphogenesis	GO:0009653	298	0.092
response to glucocorticoid	GO:0051384	223	0.090
nucleic acid templated transcription	GO:0097659	379	0.090
cell cycle checkpoint	GO:0000075	2	0.090
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.089	Mouse Rat Fly
protein complex assembly	GO:0006461	263	0.089	Human Fly
positive regulation of programmed cell death	GO:0043068	157	0.086
divalent inorganic cation transport	GO:0072511	134	0.086
positive regulation of phosphorus metabolic process	GO:0010562	262	0.086
positive regulation of biosynthetic process	GO:0009891	319	0.085
purine containing compound biosynthetic process	GO:0072522	85	0.084
positive regulation of phosphate metabolic process	GO:0045937	262	0.084
response to bacterium	GO:0009617	200	0.084
purine ribonucleoside monophosphate catabolic process	GO:0009169	55	0.083
response to external biotic stimulus	GO:0043207	221	0.083
regulation of calcium ion transmembrane transport	GO:1903169	18	0.080
muscle contraction	GO:0006936	88	0.079
regulation of calcium ion transport	GO:0051924	77	0.079
proteolysis	GO:0006508	175	0.079
cytoskeleton organization	GO:0007010	111	0.078
nucleotide catabolic process	GO:0009166	139	0.076	Mouse Rat Fly
negative regulation of transcription dna templated	GO:0045892	116	0.075
negative regulation of rna biosynthetic process	GO:1902679	118	0.075
cellular response to peptide hormone stimulus	GO:0071375	120	0.074
developmental growth	GO:0048589	100	0.074	Fly
regulation of protein modification process	GO:0031399	194	0.074	Mouse Fly
response to biotic stimulus	GO:0009607	226	0.074
cellular response to hormone stimulus	GO:0032870	247	0.073
regulation of cellular protein metabolic process	GO:0032268	267	0.073	Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	27	0.071
response to oxygen levels	GO:0070482	265	0.071
positive regulation of cell communication	GO:0010647	271	0.070
rna metabolic process	GO:0016070	406	0.069
regulation of intracellular signal transduction	GO:1902531	218	0.069
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.068
cell part morphogenesis	GO:0032990	123	0.068	Fly
cytoplasmic transport	GO:0016482	115	0.068
cell type specific apoptotic process	GO:0097285	134	0.067
cell activation	GO:0001775	97	0.067
neuron differentiation	GO:0030182	368	0.067	Mouse Fly
positive regulation of signaling	GO:0023056	270	0.067
nuclear import	GO:0051170	35	0.066
cell morphogenesis	GO:0000902	142	0.066	Human Fly
atp catabolic process	GO:0006200	54	0.065
negative regulation of gene expression	GO:0010629	199	0.065	Mouse
regulation of metal ion transport	GO:0010959	118	0.065
synaptic growth at neuromuscular junction	GO:0051124	1	0.065	Fly
positive regulation of signal transduction	GO:0009967	175	0.065
purine nucleoside monophosphate catabolic process	GO:0009128	55	0.064
response to radiation	GO:0009314	137	0.063
cell projection organization	GO:0030030	302	0.063	Human Mouse Fly
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.063	Fly
actin filament based process	GO:0030029	86	0.063
regulation of hydrolase activity	GO:0051336	143	0.062
regulation of cellular localization	GO:0060341	263	0.062
protein oligomerization	GO:0051259	191	0.061
synaptic transmission	GO:0007268	235	0.061
regulation of response to stress	GO:0080134	126	0.061
purine ribonucleoside metabolic process	GO:0046128	168	0.061	Mouse Rat Fly
dna packaging	GO:0006323	4	0.061
positive regulation of nervous system development	GO:0051962	178	0.061
cellular homeostasis	GO:0019725	252	0.060
cellular response to organonitrogen compound	GO:0071417	197	0.060
response to purine containing compound	GO:0014074	126	0.060
reproduction	GO:0000003	245	0.060	Fly
response to molecule of bacterial origin	GO:0002237	194	0.059
positive regulation of protein phosphorylation	GO:0001934	135	0.059	Mouse Fly
response to other organism	GO:0051707	220	0.059
cellular nitrogen compound catabolic process	GO:0044270	163	0.058	Mouse Rat Fly
mapk cascade	GO:0000165	140	0.058
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.058
regulation of neuron differentiation	GO:0045664	208	0.057	Fly
response to inorganic substance	GO:0010035	377	0.057
regulation of actin filament based process	GO:0032970	42	0.057	Fly
organophosphate catabolic process	GO:0046434	148	0.056	Mouse Rat Fly
glycosyl compound metabolic process	GO:1901657	182	0.056	Mouse Rat Fly
response to hypoxia	GO:0001666	231	0.056
purine ribonucleotide catabolic process	GO:0009154	136	0.054	Mouse Rat Fly
regulation of protein transport	GO:0051223	68	0.054
regulation of signal transduction	GO:0009966	318	0.053
regulation of cell development	GO:0060284	263	0.052	Human Fly
regulation of cellular amine metabolic process	GO:0033238	8	0.051
organic cyclic compound catabolic process	GO:1901361	175	0.051	Mouse Rat Fly
establishment of neuroblast polarity	GO:0045200	1	0.050	Fly
regulation of cellular component organization	GO:0051128	368	0.050
negative regulation of programmed cell death	GO:0043069	183	0.050
neuron projection development	GO:0031175	273	0.050	Fly
regulation of organelle organization	GO:0033043	80	0.049	Human Mouse Fly
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.049
nucleoside triphosphate catabolic process	GO:0009143	123	0.049	Mouse Rat Fly
regulation of secretion by cell	GO:1903530	208	0.048
response to carbohydrate	GO:0009743	183	0.048
negative regulation of apoptotic process	GO:0043066	181	0.047
positive regulation of cellular component organization	GO:0051130	200	0.046
regulation of transporter activity	GO:0032409	50	0.046
cardiovascular system development	GO:0072358	134	0.046
negative regulation of protein metabolic process	GO:0051248	114	0.046
positive regulation of catalytic activity	GO:0043085	184	0.046
leukocyte activation	GO:0045321	76	0.046
nucleoside phosphate biosynthetic process	GO:1901293	102	0.045
regulation of calcium ion transmembrane transporter activity	GO:1901019	17	0.045
chromosome segregation	GO:0007059	2	0.045	Human
muscle system process	GO:0003012	115	0.045
negative regulation of macromolecule metabolic process	GO:0010605	260	0.044	Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.044	Mouse Rat Fly
cellular calcium ion homeostasis	GO:0006874	160	0.044
cellular protein localization	GO:0034613	122	0.044
circulatory system development	GO:0072359	134	0.044
heterocycle catabolic process	GO:0046700	167	0.044	Mouse Rat Fly
exocytosis	GO:0006887	60	0.043
protein transport	GO:0015031	132	0.043
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.043
regulation of mapk cascade	GO:0043408	116	0.043
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.043
inflammatory response	GO:0006954	150	0.042
dephosphorylation	GO:0016311	98	0.042
positive regulation of intracellular signal transduction	GO:1902533	138	0.042
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.041
secretion	GO:0046903	307	0.041
response to monosaccharide	GO:0034284	159	0.041
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.041	Mouse Rat Fly
single organism biosynthetic process	GO:0044711	342	0.041
calcium ion transmembrane transport	GO:0070588	70	0.040
purine nucleotide catabolic process	GO:0006195	136	0.039	Mouse Rat Fly
t cell activation	GO:0042110	29	0.039
smad protein complex assembly	GO:0007183	1	0.039
immune system process	GO:0002376	204	0.038	Mouse Rat Fly
purine nucleoside metabolic process	GO:0042278	169	0.038	Mouse Rat Fly
response to oxidative stress	GO:0006979	186	0.038
response to estrogen	GO:0043627	232	0.038
positive regulation of transferase activity	GO:0051347	81	0.038	Mouse Fly
regulation of nucleotide metabolic process	GO:0006140	117	0.036
heart development	GO:0007507	72	0.036	Mouse
regulation of immune response	GO:0050776	55	0.036
muscle structure development	GO:0061061	87	0.036
guanosine containing compound metabolic process	GO:1901068	74	0.036	Mouse Rat Fly
positive regulation of cellular biosynthetic process	GO:0031328	295	0.035
aging	GO:0007568	241	0.035
single organism organelle organization	GO:1902589	180	0.035
regulation of ion transmembrane transporter activity	GO:0032412	48	0.035
multicellular organism growth	GO:0035264	1	0.034	Mouse
neuron apoptotic process	GO:0051402	88	0.034
nucleotide biosynthetic process	GO:0009165	98	0.034
cellular ketone metabolic process	GO:0042180	51	0.034
purine nucleotide biosynthetic process	GO:0006164	83	0.034
regulation of response to wounding	GO:1903034	69	0.033	Fly
myeloid leukocyte activation	GO:0002274	36	0.033
establishment of protein localization to organelle	GO:0072594	44	0.033
chromosome organization	GO:0051276	36	0.033
regulation of response to external stimulus	GO:0032101	106	0.033
heart morphogenesis	GO:0003007	3	0.033
negative regulation of transport	GO:0051051	136	0.033
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.033	Human Fly
regeneration	GO:0031099	163	0.032
asymmetric stem cell division	GO:0098722	2	0.032	Fly
cell cell signaling	GO:0007267	335	0.032
cellular amine metabolic process	GO:0044106	38	0.032
peptidyl amino acid modification	GO:0018193	126	0.032	Mouse
vesicle mediated transport	GO:0016192	181	0.032	Fly
nitrogen compound transport	GO:0071705	229	0.032
negative regulation of cell death	GO:0060548	229	0.032
positive regulation of cellular amine metabolic process	GO:0033240	3	0.032
neuron projection morphogenesis	GO:0048812	122	0.032	Fly
guanosine containing compound catabolic process	GO:1901069	71	0.031	Mouse Rat Fly
response to wounding	GO:0009611	254	0.031	Fly
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.031
response to decreased oxygen levels	GO:0036293	237	0.031
cell cycle	GO:0007049	101	0.030	Human Mouse
response to lipopolysaccharide	GO:0032496	191	0.030
calcium ion homeostasis	GO:0055074	162	0.030
regulation of kinase activity	GO:0043549	117	0.030	Mouse Fly
single organism reproductive process	GO:0044702	297	0.030	Fly
cation homeostasis	GO:0055080	195	0.030
protein maturation	GO:0051604	68	0.030
protein localization	GO:0008104	191	0.029
regulation of proteolysis	GO:0030162	66	0.029
response to metal ion	GO:0010038	253	0.029
vesicle localization	GO:0051648	33	0.029
transcription from rna polymerase ii promoter	GO:0006366	252	0.029
positive regulation of transcription dna templated	GO:0045893	197	0.029
regulation of ion transmembrane transport	GO:0034765	121	0.028
small gtpase mediated signal transduction	GO:0007264	36	0.028	Fly
positive regulation of mapk cascade	GO:0043410	92	0.028
regulation of purine nucleotide biosynthetic process	GO:1900371	46	0.028
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	41	0.028	Human
nucleoside phosphate catabolic process	GO:1901292	140	0.028	Mouse Rat Fly
positive regulation of cell proliferation	GO:0008284	249	0.028	Mouse
heat acclimation	GO:0010286	1	0.028
carbohydrate derivative catabolic process	GO:1901136	147	0.028	Mouse Rat Fly
cell cycle process	GO:0022402	57	0.028	Human Mouse
response to cytokine	GO:0034097	215	0.027
protein heterooligomerization	GO:0051291	89	0.027
divalent inorganic cation homeostasis	GO:0072507	165	0.027
cellular component movement	GO:0006928	248	0.027
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.027
carbohydrate derivative biosynthetic process	GO:1901137	124	0.027
negative regulation of cell proliferation	GO:0008285	119	0.027
cell projection assembly	GO:0030031	21	0.026	Human Mouse Fly
regulation of neuron projection development	GO:0010975	161	0.026	Fly
wound healing	GO:0042060	122	0.026	Fly
regulation of anatomical structure size	GO:0090066	135	0.026	Fly
response to extracellular stimulus	GO:0009991	380	0.026
response to hydrogen peroxide	GO:0042542	89	0.026
regulation of muscle system process	GO:0090257	79	0.026
positive regulation of neurogenesis	GO:0050769	165	0.026
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.026
positive regulation of neuron projection development	GO:0010976	99	0.026
nuclear transport	GO:0051169	49	0.026
macromolecule catabolic process	GO:0009057	58	0.025	Mouse
response to antibiotic	GO:0046677	39	0.025
mitotic cell cycle phase transition	GO:0044772	20	0.025
establishment or maintenance of neuroblast polarity	GO:0045196	1	0.025	Fly
ras protein signal transduction	GO:0007265	29	0.025	Fly
homeostatic process	GO:0042592	331	0.025	Rat
protein autophosphorylation	GO:0046777	66	0.025
reproductive process	GO:0022414	372	0.025	Fly
positive regulation of phosphorylation	GO:0042327	177	0.025
sexual reproduction	GO:0019953	148	0.025	Fly
nucleobase containing compound catabolic process	GO:0034655	152	0.024	Mouse Rat Fly
regulation of dendrite morphogenesis	GO:0048814	33	0.024
blood circulation	GO:0008015	183	0.024	Mouse
mitotic cell cycle process	GO:1903047	35	0.024	Mouse
positive regulation of immune response	GO:0050778	42	0.024
dendrite morphogenesis	GO:0048813	43	0.024	Fly
mitotic dna damage checkpoint	GO:0044773	1	0.024
neuron death	GO:0070997	127	0.024
lymphocyte activation	GO:0046649	43	0.024
organophosphate biosynthetic process	GO:0090407	143	0.024
cellular response to abiotic stimulus	GO:0071214	85	0.024
regulation of dna metabolic process	GO:0051052	60	0.024
protein import into nucleus	GO:0006606	35	0.024
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.024
organonitrogen compound catabolic process	GO:1901565	179	0.023	Mouse Rat Fly
positive regulation of cell development	GO:0010720	176	0.023	Human
cellular amino acid metabolic process	GO:0006520	107	0.023
regulation of developmental growth	GO:0048638	45	0.023	Fly
response to reactive oxygen species	GO:0000302	120	0.023
striated muscle tissue development	GO:0014706	58	0.023	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	106	0.023
regulation of transmembrane transport	GO:0034762	122	0.023
purine ribonucleotide biosynthetic process	GO:0009152	81	0.022
chaperone mediated protein folding	GO:0061077	6	0.022
response to ethanol	GO:0045471	162	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.022	Mouse Rat Fly
cellular ion homeostasis	GO:0006873	184	0.022
negative regulation of mitotic cell cycle phase transition	GO:1901991	3	0.022
organonitrogen compound biosynthetic process	GO:1901566	167	0.022
muscle tissue development	GO:0060537	58	0.022	Mouse
response to increased oxygen levels	GO:0036296	45	0.022
regulation of cellular ketone metabolic process	GO:0010565	27	0.022
heart contraction	GO:0060047	57	0.022	Mouse
positive regulation of purine nucleotide biosynthetic process	GO:1900373	36	0.022
regulation of cell migration	GO:0030334	128	0.022
negative regulation of molecular function	GO:0044092	133	0.022
negative regulation of cell cycle phase transition	GO:1901988	4	0.022
hormone transport	GO:0009914	121	0.021
positive regulation of nucleotide metabolic process	GO:0045981	91	0.021
activation of protein kinase activity	GO:0032147	47	0.021
regulation of cell projection organization	GO:0031344	175	0.021	Human Fly
nucleocytoplasmic transport	GO:0006913	48	0.021
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.021
single organism cellular localization	GO:1902580	102	0.021
mitotic cell cycle	GO:0000278	49	0.021	Mouse
regulation of nucleoside metabolic process	GO:0009118	66	0.021
secretion by cell	GO:0032940	248	0.021
regulation of purine nucleotide catabolic process	GO:0033121	65	0.021
signal transduction by phosphorylation	GO:0023014	144	0.021
response to transition metal nanoparticle	GO:1990267	122	0.021
regulation of cellular amino acid metabolic process	GO:0006521	2	0.020
circulatory system process	GO:0003013	183	0.020	Mouse
spermatogenesis	GO:0007283	99	0.020	Fly
positive regulation of catabolic process	GO:0009896	78	0.020
organelle localization	GO:0051640	55	0.020
tissue development	GO:0009888	252	0.020	Mouse Fly
cell growth	GO:0016049	104	0.020
positive regulation of rna metabolic process	GO:0051254	203	0.020
dna integrity checkpoint	GO:0031570	2	0.020
cellular component assembly	GO:0022607	360	0.020	Human Mouse Fly
regulation of muscle contraction	GO:0006937	53	0.020
protein localization to nucleus	GO:0034504	39	0.019
cellular response to glucocorticoid stimulus	GO:0071385	68	0.019
response to heat	GO:0009408	60	0.019
metal ion homeostasis	GO:0055065	186	0.019
neuronal stem cell division	GO:0036445	1	0.019	Fly
positive regulation of neuron differentiation	GO:0045666	126	0.019
positive regulation of cellular catabolic process	GO:0031331	71	0.019
chemical homeostasis	GO:0048878	292	0.019
regulation of protein serine threonine kinase activity	GO:0071900	64	0.019
intracellular protein transport	GO:0006886	79	0.019
cytosolic calcium ion homeostasis	GO:0051480	140	0.019
organ regeneration	GO:0031100	101	0.019
positive regulation of kinase activity	GO:0033674	77	0.019	Mouse Fly
positive regulation of protein kinase activity	GO:0045860	73	0.019	Fly
response to glucose	GO:0009749	136	0.018
defense response	GO:0006952	194	0.018	Fly
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.018
regulation of purine nucleotide metabolic process	GO:1900542	115	0.018
negative regulation of catalytic activity	GO:0043086	103	0.018
regulation of transmembrane transporter activity	GO:0022898	49	0.018
regulation of adenylate cyclase activity	GO:0045761	18	0.018
negative regulation of response to stimulus	GO:0048585	155	0.018
glial cell differentiation	GO:0010001	65	0.018
response to alkaloid	GO:0043279	132	0.018
positive regulation of secretion	GO:0051047	140	0.018
protein targeting	GO:0006605	61	0.018
positive regulation of rna biosynthetic process	GO:1902680	197	0.017
regulation of neuron death	GO:1901214	115	0.017
developmental process involved in reproduction	GO:0003006	159	0.017	Fly
cell cycle phase transition	GO:0044770	21	0.017
mitochondrion organization	GO:0007005	35	0.017
nucleoside metabolic process	GO:0009116	179	0.017	Mouse Rat Fly
cellular response to organic cyclic compound	GO:0071407	202	0.017
response to growth factor	GO:0070848	189	0.017
negative regulation of rna metabolic process	GO:0051253	123	0.017
response to nutrient	GO:0007584	248	0.017
molting cycle	GO:0042303	3	0.017	Mouse
cell migration	GO:0016477	197	0.017	Zebrafish Mouse Rat Fly
reactive oxygen species metabolic process	GO:0072593	37	0.017
dna metabolic process	GO:0006259	96	0.017
response to hyperoxia	GO:0055093	45	0.017
multicellular organismal reproductive process	GO:0048609	233	0.017	Fly
organic acid metabolic process	GO:0006082	292	0.017
monovalent inorganic cation transport	GO:0015672	172	0.017
response to nutrient levels	GO:0031667	370	0.017
negative regulation of protein maturation	GO:1903318	47	0.017
regulation of intracellular transport	GO:0032386	65	0.017
positive regulation of cell projection organization	GO:0031346	111	0.017	Human Fly
organic hydroxy compound transport	GO:0015850	77	0.016
carboxylic acid metabolic process	GO:0019752	289	0.016
regulation of nucleotide biosynthetic process	GO:0030808	47	0.016
protein modification by small protein conjugation or removal	GO:0070647	35	0.016
calcium ion transport into cytosol	GO:0060402	38	0.016
regulation of cell morphogenesis	GO:0022604	77	0.016	Human Fly
ubiquitin dependent protein catabolic process	GO:0006511	14	0.016
protein processing	GO:0016485	68	0.016
regulation of anatomical structure morphogenesis	GO:0022603	141	0.016	Human Fly
embryonic axis specification	GO:0000578	1	0.016
amine metabolic process	GO:0009308	38	0.016
negative regulation of secretion by cell	GO:1903531	72	0.016
muscle organ development	GO:0007517	50	0.016
ion homeostasis	GO:0050801	212	0.016
protein sumoylation	GO:0016925	4	0.016
regulation of neurogenesis	GO:0050767	247	0.016	Fly
cellular response to growth factor stimulus	GO:0071363	162	0.015
regulation of hormone levels	GO:0010817	187	0.015
cellular cation homeostasis	GO:0030003	180	0.015
multicellular organismal homeostasis	GO:0048871	49	0.015	Rat
cytokine mediated signaling pathway	GO:0019221	43	0.015
ribonucleotide biosynthetic process	GO:0009260	85	0.015
positive regulation of growth	GO:0045927	55	0.015
cyclic nucleotide biosynthetic process	GO:0009190	63	0.015
establishment of vesicle localization	GO:0051650	31	0.015
regulation of cellular catabolic process	GO:0031329	101	0.015
regulation of cell motility	GO:2000145	131	0.015
pigment biosynthetic process	GO:0046148	4	0.015
modification dependent macromolecule catabolic process	GO:0043632	14	0.015
regulation of cellular component biogenesis	GO:0044087	86	0.015	Human Fly
brain development	GO:0007420	247	0.015	Human
cellular metal ion homeostasis	GO:0006875	172	0.014
positive regulation of dna metabolic process	GO:0051054	39	0.014
multi organism reproductive process	GO:0044703	262	0.014	Fly
actin cytoskeleton organization	GO:0030036	73	0.014
organelle assembly	GO:0070925	22	0.014
neuron development	GO:0048666	286	0.014	Fly
sequestering of calcium ion	GO:0051208	8	0.014
atp metabolic process	GO:0046034	72	0.014
reactive oxygen species biosynthetic process	GO:1903409	8	0.014
reproductive structure development	GO:0048608	128	0.014
epithelium development	GO:0060429	96	0.014	Mouse Fly
rho protein signal transduction	GO:0007266	11	0.013	Fly
cell adhesion	GO:0007155	110	0.013	Human Mouse
negative regulation of protein processing	GO:0010955	47	0.013
embryonic pattern specification	GO:0009880	1	0.013
positive regulation of purine nucleotide catabolic process	GO:0033123	53	0.013
regulation of blood circulation	GO:1903522	110	0.013
embryo development	GO:0009790	49	0.013	Zebrafish Fly
protein modification by small protein conjugation	GO:0032446	31	0.013
sodium ion transmembrane transport	GO:0035725	67	0.013
innate immune response	GO:0045087	35	0.013	Fly
regulation of growth	GO:0040008	105	0.013	Fly
protein polyubiquitination	GO:0000209	3	0.013
regulation of transferase activity	GO:0051338	123	0.013	Mouse Fly
dna damage checkpoint	GO:0000077	2	0.013
regulation of peptidase activity	GO:0052547	55	0.013
cyclic purine nucleotide metabolic process	GO:0052652	62	0.013
positive regulation of dendrite morphogenesis	GO:0050775	21	0.012
negative regulation of cell communication	GO:0010648	158	0.012
response to mechanical stimulus	GO:0009612	134	0.012
development of primary sexual characteristics	GO:0045137	107	0.012

Cdc42 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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