Rattus norvegicus

33 known processes

Pdha2

pyruvate dehydrogenase (lipoamide) alpha 2

(Aliases: Pdhal)

Pdha2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism reproductive processGO:00447022970.205
response to nutrient levelsGO:00316673700.194
response to extracellular stimulusGO:00099913800.194
cellular response to endogenous stimulusGO:00714953770.187
oxoacid metabolic processGO:00434362900.171
carboxylic acid metabolic processGO:00197522890.153
cellular response to organonitrogen compoundGO:00714171970.142
organic acid metabolic processGO:00060822920.135
response to campGO:0051591910.108
organic substance catabolic processGO:19015753160.104
catabolic processGO:00090563510.098
single organism biosynthetic processGO:00447113420.098
single organism catabolic processGO:00447122830.096
multicellular organism reproductionGO:00325042330.093
regulation of programmed cell deathGO:00430673410.093
negative regulation of nitrogen compound metabolic processGO:00511721610.093
regulation of multicellular organismal developmentGO:20000263760.090
metanephric comma shaped body morphogenesisGO:007227820.088
cellular response to growth factor stimulusGO:00713631620.085
nucleobase containing small molecule metabolic processGO:00550863160.085
purine containing compound metabolic processGO:00725212530.082
cellular response to stressGO:00335542690.082
programmed cell deathGO:00125013920.082
reproductive processGO:00224143720.079
cellular response to nitrogen compoundGO:19016992100.078
response to ketoneGO:19016541820.072
response to biotic stimulusGO:00096072260.070
positive regulation of apoptotic processGO:00430651540.069
response to organophosphorusGO:00466831020.068
cardiac ventricle developmentGO:000323110.066
response to nutrientGO:00075842480.063
organonitrogen compound biosynthetic processGO:19015661670.063
regulation of membrane repolarizationGO:006030610.063
response to external biotic stimulusGO:00432072210.060
nucleoside metabolic processGO:00091161790.059
brain developmentGO:00074202470.059
transmission of nerve impulseGO:0019226420.059
cellular response to peptide hormone stimulusGO:00713751200.058
cellular response to hormone stimulusGO:00328702470.058
developmental process involved in reproductionGO:00030061590.057
cellular response to insulin stimulusGO:0032869810.057
defense responseGO:00069521940.057
cellular response to cytokine stimulusGO:00713451270.056
gonad developmentGO:00084061040.056
response to glucocorticoidGO:00513842230.055
lipid biosynthetic processGO:00086101280.054
cellular catabolic processGO:00442482950.053
response to other organismGO:00517072200.052
response to chromateGO:004668730.049
positive regulation of cell proliferationGO:00082842490.049
positive regulation of signalingGO:00230562700.049
reproductive structure developmentGO:00486081280.048
response to amineGO:0014075460.048
renin angiotensin regulation of aldosterone productionGO:000201830.048
antral ovarian follicle growthGO:000154730.048
epithelium developmentGO:0060429960.046
reproductive system developmentGO:00614581280.045
tissue developmentGO:00098882520.045
multicellular organismal reproductive processGO:00486092330.045
central nervous system developmentGO:00074173110.045
chemical homeostasisGO:00488782920.045
response to cytokineGO:00340972150.045
nucleoside phosphate metabolic processGO:00067532830.044
rna metabolic processGO:00160704060.044
cellular response to oxygen containing compoundGO:19017013860.042
response to ethanolGO:00454711620.042
response to oxygen levelsGO:00704822650.041
neural crest cell migrationGO:000175510.041
g protein coupled receptor signaling pathwayGO:00071862420.041
neural crest cell differentiationGO:001403320.040
negative regulation of macromolecule metabolic processGO:00106052600.040
lipid metabolic processGO:00066292830.040
cellular component biogenesisGO:00440853680.039
secretionGO:00469033070.039
response to peptide hormoneGO:00434342780.039
neural crest cell developmentGO:001403220.038
cell cell signalingGO:00072673350.038
stress activated protein kinase signaling cascadeGO:0031098370.038
protein transportGO:00150311320.038
organophosphate biosynthetic processGO:00904071430.038
rna biosynthetic processGO:00327743800.037
rhythmic processGO:00485111560.037
purine nucleotide metabolic processGO:00061632290.036
response to lipopolysaccharideGO:00324961910.036
heart morphogenesisGO:000300730.036
membrane repolarizationGO:008600910.035
neurological system processGO:00508772190.035
macromolecular complex assemblyGO:00650032730.035
protein localizationGO:00081041910.035
negative regulation of metabolic processGO:00098923310.035
cation homeostasisGO:00550801950.034
anatomical structure morphogenesisGO:00096532980.034
artery smooth muscle contractionGO:001482440.034
developmental growthGO:00485891000.034
cellular response to peptideGO:19016531330.034
regulation of rna metabolic processGO:00512523910.034
head developmentGO:00603222470.033
growthGO:00400071650.033
response to purine containing compoundGO:00140741260.033
organonitrogen compound catabolic processGO:19015651790.033
development of primary sexual characteristicsGO:00451371070.033
macromolecular complex subunit organizationGO:00439333390.033
organic acid biosynthetic processGO:0016053830.032
cellular amino acid metabolic processGO:00065201070.032
negative regulation of rna metabolic processGO:00512531230.032
cellular divalent inorganic cation homeostasisGO:00725031620.032
regulation of cell proliferationGO:00421273590.032
ion homeostasisGO:00508012120.032
regulation of secretionGO:00510462240.032
protein targetingGO:0006605610.031
protein complex assemblyGO:00064612630.031
monocarboxylic acid metabolic processGO:00327871520.031
negative regulation of cellular biosynthetic processGO:00313271610.031
cellular response to organic cyclic compoundGO:00714072020.030
regulation of rna biosynthetic processGO:20011413810.030
positive regulation of cell deathGO:00109421840.030
regulation of nucleic acid templated transcriptionGO:19035063800.030
amine metabolic processGO:0009308380.030
regulation of molecular functionGO:00650093980.029
cellular response to campGO:0071320260.029
nucleotide biosynthetic processGO:0009165980.029
aromatic compound catabolic processGO:00194391680.029
intracellular signal transductionGO:00355563140.029
positive regulation of programmed cell deathGO:00430681570.029
gamete generationGO:00072761240.029
feeding behaviorGO:0007631530.028
negative regulation of macromolecule biosynthetic processGO:00105581480.028
circulatory system developmentGO:00723591340.028
organophosphate catabolic processGO:00464341480.028
intracellular protein transportGO:0006886790.028
regulation of apoptotic processGO:00429813350.027
purine nucleotide biosynthetic processGO:0006164830.027
establishment of protein localization to organelleGO:0072594440.027
homeostatic processGO:00425923310.027
nucleotide metabolic processGO:00091172790.026
response to decreased oxygen levelsGO:00362932370.026
heterocycle catabolic processGO:00467001670.026
positive regulation of developmental processGO:00510942830.026
negative regulation of gene expressionGO:00106291990.026
muscle structure developmentGO:0061061870.025
regulation of catalytic activityGO:00507903040.025
response to activityGO:0014823730.025
carbohydrate derivative catabolic processGO:19011361470.025
monocarboxylic acid biosynthetic processGO:0072330480.025
apoptotic processGO:00069153810.025
multi organism reproductive processGO:00447032620.025
intracellular transportGO:00469071850.025
negative regulation of transcription dna templatedGO:00458921160.025
response to estrogenGO:00436272320.024
cardiovascular system developmentGO:00723581340.024
response to inorganic substanceGO:00100353770.024
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.024
immune system processGO:00023762040.024
positive regulation of biosynthetic processGO:00098913190.024
proteolysisGO:00065081750.024
axis specificationGO:000979840.024
positive regulation of nitrogen compound metabolic processGO:00511733340.023
protein complex subunit organizationGO:00718223020.023
response to testosteroneGO:0033574550.023
response to mineralocorticoidGO:0051385490.023
regulation of phosphate metabolic processGO:00192203490.023
cellular lipid metabolic processGO:00442552080.022
regulation of phosphorus metabolic processGO:00511743490.022
nucleoside phosphate biosynthetic processGO:19012931020.022
inflammatory responseGO:00069541500.022
response to amino acidGO:0043200750.022
regulation of transcription dna templatedGO:00063553740.022
response to cocaineGO:0042220390.022
negative regulation of rna biosynthetic processGO:19026791180.022
sexual reproductionGO:00199531480.022
response to toxic substanceGO:00096361330.021
muscle cell differentiationGO:0042692520.021
protein localization to organelleGO:0033365570.021
cellular amine metabolic processGO:0044106380.021
regulation of system processGO:00440572080.021
female gonad developmentGO:0008585530.021
cellular hormone metabolic processGO:0034754490.021
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
fatty acid metabolic processGO:0006631990.021
response to corticosteroneGO:0051412400.021
development of primary female sexual characteristicsGO:0046545560.021
organic cyclic compound catabolic processGO:19013611750.021
nuclear transportGO:0051169490.020
hormone metabolic processGO:0042445690.020
metanephric s shaped body morphogenesisGO:007228420.020
cell growthGO:00160491040.020
regulation of protein metabolic processGO:00512462890.020
small molecule biosynthetic processGO:00442831240.020
negative regulation of cellular metabolic processGO:00313242810.020
response to growth factorGO:00708481890.020
cardiac muscle tissue developmentGO:0048738260.020
cellular protein localizationGO:00346131220.020
circadian rhythmGO:0007623880.020
localization of cellGO:00516742020.020
metanephric part of ureteric bud developmentGO:003550210.020
negative regulation of apoptotic processGO:00430661810.020
cardiac muscle cell developmentGO:0055013160.020
regulation of blood vessel sizeGO:0050880890.019
purine containing compound catabolic processGO:00725231380.019
response to amphetamineGO:0001975250.019
response to transition metal nanoparticleGO:19902671220.019
cellular response to lipidGO:00713962010.019
peptide biosynthetic processGO:004304330.019
regenerationGO:00310991630.019
nitrogen compound transportGO:00717052290.019
mitotic sister chromatid separationGO:005130610.019
response to peptideGO:19016522920.019
ribonucleotide biosynthetic processGO:0009260850.019
reproductionGO:00000032450.019
cellular chemical homeostasisGO:00550822470.019
vascular process in circulatory systemGO:0003018960.019
sex differentiationGO:00075481130.019
organ growthGO:0035265240.018
positive regulation of cell differentiationGO:00455972170.018
regulation of catabolic processGO:00098941130.018
regulation of blood volume by renal aldosteroneGO:000201710.018
ribose phosphate metabolic processGO:00196932350.018
protein oligomerizationGO:00512591910.018
regulation of ion transportGO:00432692450.018
response to vitaminGO:00332731310.018
epithelial cell proliferationGO:0050673540.018
salivary gland developmentGO:000743130.018
oxidation reduction processGO:00551143040.018
response to corticosteroidGO:00319602350.017
cellular metal ion homeostasisGO:00068751720.017
cellular nitrogen compound catabolic processGO:00442701630.017
heart growthGO:0060419200.017
spermatogenesisGO:0007283990.017
negative regulation of molecular functionGO:00440921330.017
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.017
protein complex biogenesisGO:00702712630.017
secretion by cellGO:00329402480.017
cellular macromolecule localizationGO:00707271220.017
ribose phosphate biosynthetic processGO:0046390870.017
comma shaped body morphogenesisGO:007204920.017
purine ribonucleotide biosynthetic processGO:0009152810.017
negative regulation of programmed cell deathGO:00430691830.017
regulation of ion homeostasisGO:2000021630.017
carboxylic acid biosynthetic processGO:0046394830.017
purine ribonucleoside catabolic processGO:00461301240.017
cardiac cell developmentGO:0055006160.017
carbohydrate derivative metabolic processGO:19011353460.017
response to metal ionGO:00100382530.016
muscle tissue developmentGO:0060537580.016
striated muscle tissue developmentGO:0014706580.016
positive regulation of multicellular organismal processGO:00512403870.016
purine containing compound biosynthetic processGO:0072522850.016
organic anion transportGO:00157111320.016
eye developmentGO:0001654500.016
cellular response to external stimulusGO:00714961180.016
fatty acid biosynthetic processGO:0006633330.016
behaviorGO:00076102050.016
purine ribonucleoside monophosphate metabolic processGO:0009167840.016
multi multicellular organism processGO:00447061380.016
cognitionGO:0050890920.016
negative regulation of protein metabolic processGO:00512481140.016
cellular component assemblyGO:00226073600.015
response to herbicideGO:0009635160.015
negative regulation of biosynthetic processGO:00098901680.015
circulatory system processGO:00030131830.015
multicellular organismal signalingGO:0035637440.015
negative regulation of cell communicationGO:00106481580.015
purine ribonucleoside metabolic processGO:00461281680.015
response to carbohydrateGO:00097431830.015
response to hypoxiaGO:00016662310.015
single organism cell adhesionGO:0098602460.015
establishment of protein localizationGO:00451841410.015
response to molecule of bacterial originGO:00022371940.015
muscle organ developmentGO:0007517500.015
regulation of cellular ketone metabolic processGO:0010565270.015
regulation of intracellular signal transductionGO:19025312180.015
positive regulation of cell communicationGO:00106472710.015
transcription dna templatedGO:00063513770.015
epithelial cell differentiationGO:0030855710.015
positive regulation of cellular amine metabolic processGO:003324030.014
synaptic transmissionGO:00072682350.014
regulation of cellular catabolic processGO:00313291010.014
cellular response to glucocorticoid stimulusGO:0071385680.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
response to insulinGO:00328681330.014
neuronal action potentialGO:0019228350.014
anterior posterior pattern specificationGO:000995210.014
regulation of serine type peptidase activityGO:190257110.014
muscle tissue morphogenesisGO:006041510.014
chylomicron remodelingGO:003437110.014
liver developmentGO:0001889900.014
cell differentiation involved in kidney developmentGO:006100540.014
regulation of cellular component organizationGO:00511283680.014
nephric duct developmentGO:007217610.014
cellular sodium ion homeostasisGO:000688340.014
gastrulationGO:000736920.014
regulation of nervous system developmentGO:00519602640.014
cardiac conductionGO:006133720.014
s shaped body morphogenesisGO:007205020.014
adrenal gland developmentGO:0030325110.014
telencephalon developmentGO:0021537620.014
choline transportGO:001587140.014
regulation of purine nucleotide metabolic processGO:19005421150.014
cellular response to corticosteroid stimulusGO:0071384690.014
protein importGO:0017038370.014
ribonucleotide catabolic processGO:00092611360.014
drinking behaviorGO:0042756110.014
biological adhesionGO:00226101100.014
nuclear importGO:0051170350.014
chromosome segregationGO:000705920.014
ribonucleotide metabolic processGO:00092592310.013
regulation of kinase activityGO:00435491170.013
response to dexamethasoneGO:0071548490.013
positive regulation of catalytic activityGO:00430851840.013
response to follicle stimulating hormoneGO:0032354180.013
regulation of epithelial cell proliferationGO:0050678490.013
negative regulation of multicellular organismal processGO:00512412030.013
response to bacteriumGO:00096172000.013
single organismal cell cell adhesionGO:0016337420.013
regulation of cellular protein metabolic processGO:00322682670.013
negative regulation of cell cycle phase transitionGO:190198840.013
response to acid chemicalGO:00011012220.013
organophosphate metabolic processGO:00196373700.013
purine nucleoside biosynthetic processGO:0042451210.013
positive regulation of cell developmentGO:00107201760.013
cell adhesionGO:00071551100.013
embryonic pattern specificationGO:000988010.013
mapk cascadeGO:00001651400.013
positive regulation of growthGO:0045927550.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
regulation of transferase activityGO:00513381230.013
muscle organ morphogenesisGO:004864410.013
anion transportGO:00068201780.013
response to gonadotropinGO:0034698340.013
cellular ketone metabolic processGO:0042180510.012
regulation of long term neuronal synaptic plasticityGO:0048169150.012
regulation of cellular amino acid metabolic processGO:000652120.012
regulation of blood circulationGO:19035221100.012
regulation of homeostatic processGO:00328441010.012
regulation of protein kinase activityGO:00458591050.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
response to methanolGO:003398610.012
positive regulation of response to stimulusGO:00485842850.012
positive regulation of molecular functionGO:00440932300.012
positive regulation of cell growthGO:0030307440.012
cyclic nucleotide metabolic processGO:0009187800.012
nucleobase containing compound catabolic processGO:00346551520.012
single organism cellular localizationGO:19025801020.012
hepaticobiliary system developmentGO:0061008900.012
cardiac muscle tissue growthGO:0055017200.012
phthalate metabolic processGO:001896380.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
negative regulation of cell proliferationGO:00082851190.012
response to fatty acidGO:0070542650.012
chemokine metabolic processGO:005075530.012
negative regulation of peptidase activityGO:0010466380.012
positive regulation of signal transductionGO:00099671750.012
fertilizationGO:000956630.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
cell communication involved in cardiac conductionGO:008606520.011
cellular response to extracellular stimulusGO:0031668730.011
negative regulation of developmental processGO:00510931250.011
regulation of neurogenesisGO:00507672470.011
purine ribonucleotide metabolic processGO:00091502270.011
regulation of map kinase activityGO:0043405530.011
cellular homeostasisGO:00197252520.011
positive regulation of transportGO:00510502450.011
transmembrane transportGO:00550854120.011
organelle organizationGO:00069962660.011
cytokine productionGO:0001816610.011
positive regulation of transferase activityGO:0051347810.011
negative regulation of cellular protein metabolic processGO:00322691060.011
amine transportGO:0015837570.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
negative regulation of growthGO:0045926370.011
calcium ion homeostasisGO:00550741620.011
cellular lipid catabolic processGO:0044242370.011
regulation of protein serine threonine kinase activityGO:0071900640.011
immune responseGO:00069551040.011
positive regulation of intracellular signal transductionGO:19025331380.011
reactive nitrogen species metabolic processGO:200105710.011
negative regulation of catalytic activityGO:00430861030.011
cell cycle checkpointGO:000007520.011
cardiac chamber developmentGO:000320510.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
fractalkine metabolic processGO:005075630.011
cytoplasmic transportGO:00164821150.011
nucleoside phosphate catabolic processGO:19012921400.011
regulation of secretion by cellGO:19035302080.011
renal system process involved in regulation of systemic arterial blood pressureGO:0003071140.011
adult locomotory behaviorGO:000834440.011
response to fungicideGO:0060992200.011
regulation of proteolysisGO:0030162660.011
tissue remodelingGO:0048771400.010
protein homooligomerizationGO:0051260910.010
heart developmentGO:0007507720.010
response to cadmium ionGO:0046686350.010
regulation of signal transductionGO:00099663180.010
positive regulation of transcription dna templatedGO:00458931970.010
lipid localizationGO:0010876620.010
cellular component morphogenesisGO:00329891550.010
very low density lipoprotein particle remodelingGO:003437210.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
ionotropic glutamate receptor signaling pathwayGO:0035235340.010
cgmp catabolic processGO:004606960.010
negative regulation of neuron differentiationGO:0045665620.010
response to zinc ionGO:0010043390.010
nucleocytoplasmic transportGO:0006913480.010
positive regulation of protein serine threonine kinase activityGO:0071902520.010
epithelial cell differentiation involved in kidney developmentGO:003585030.010

Pdha2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.024
disease of metabolismDOID:001466700.024
lipid metabolism disorderDOID:314600.023
steroid inherited metabolic disorderDOID:170100.023
congenital adrenal hyperplasiaDOID:005081100.023
disease of cellular proliferationDOID:1456600.016
urinary system diseaseDOID:1800.016
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.014