Rattus norvegicus

33 known processes

Pdha1

pyruvate dehydrogenase (lipoamide) alpha 1

(Aliases: MGC114215,MGC94854)

Pdha1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
acyl coa biosynthetic processGO:007161670.760
cofactor biosynthetic processGO:0051188280.711
acyl coa metabolic processGO:0006637280.702
carboxylic acid metabolic processGO:00197522890.656
sulfur compound biosynthetic processGO:0044272190.631
oxoacid metabolic processGO:00434362900.595
dicarboxylic acid metabolic processGO:0043648420.529
response to inorganic substanceGO:00100353770.403
coenzyme metabolic processGO:0006732860.296
single organism biosynthetic processGO:00447113420.290
regulation of phosphorus metabolic processGO:00511743490.238
organic acid metabolic processGO:00060822920.229
nitrogen compound transportGO:00717052290.206
cofactor metabolic processGO:0051186950.172
homeostatic processGO:00425923310.162
chemical homeostasisGO:00488782920.146
ribonucleoside metabolic processGO:00091191740.123
cellular homeostasisGO:00197252520.106
cation transportGO:00068123820.104
thioester metabolic processGO:0035383280.099
glycosyl compound metabolic processGO:19016571820.098
purine nucleoside metabolic processGO:00422781690.095
programmed cell deathGO:00125013920.091
nucleoside metabolic processGO:00091161790.083
purine ribonucleoside triphosphate metabolic processGO:00092051400.082
oxidative phosphorylationGO:000611940.082
energy derivation by oxidation of organic compoundsGO:0015980460.082
cellular response to oxygen containing compoundGO:19017013860.081
ribonucleoside triphosphate metabolic processGO:00091991410.081
nucleotide metabolic processGO:00091172790.080
negative regulation of molecular functionGO:00440921330.079
organophosphate metabolic processGO:00196373700.079
secretion by cellGO:00329402480.077
agingGO:00075682410.076
cellular respirationGO:0045333210.075
acetyl coa biosynthetic process from pyruvateGO:000608650.073
response to lipopolysaccharideGO:00324961910.066
protein phosphorylationGO:00064683450.064
sulfur compound metabolic processGO:0006790700.063
apoptotic processGO:00069153810.059
response to molecule of bacterial originGO:00022371940.058
purine ribonucleotide metabolic processGO:00091502270.057
response to peptideGO:19016522920.057
purine ribonucleoside metabolic processGO:00461281680.056
vesicle mediated transportGO:00161921810.056
purine nucleotide metabolic processGO:00061632290.055
cellular chemical homeostasisGO:00550822470.055
cell morphogenesisGO:00009021420.055
cellular response to hormone stimulusGO:00328702470.053
ion homeostasisGO:00508012120.053
response to insulinGO:00328681330.052
regulation of phosphate metabolic processGO:00192203490.052
oxidation reduction processGO:00551143040.052
cellular metal ion homeostasisGO:00068751720.051
nucleobase containing small molecule metabolic processGO:00550863160.050
transmembrane transportGO:00550854120.049
regulation of protein metabolic processGO:00512462890.049
protein dephosphorylationGO:0006470380.048
pyruvate metabolic processGO:0006090270.047
generation of precursor metabolites and energyGO:0006091620.047
response to oxidative stressGO:00069791860.047
rna biosynthetic processGO:00327743800.046
regulation of signal transductionGO:00099663180.046
circulatory system developmentGO:00723591340.046
2 oxoglutarate metabolic processGO:000610360.046
purine ribonucleoside monophosphate metabolic processGO:0009167840.045
purine containing compound metabolic processGO:00725212530.045
mitotic spindle organizationGO:000705220.045
p38mapk cascadeGO:003806610.045
growthGO:00400071650.043
nucleoside phosphate metabolic processGO:00067532830.043
ribonucleotide metabolic processGO:00092592310.041
positive regulation of secretion by cellGO:19035321280.041
purine nucleoside monophosphate metabolic processGO:0009126840.041
response to interleukin 1GO:0070555550.041
positive regulation of cell proliferationGO:00082842490.040
protein complex subunit organizationGO:00718223020.040
metal ion homeostasisGO:00550651860.040
acetyl coa biosynthetic processGO:000608560.040
cation homeostasisGO:00550801950.040
regulation of secretionGO:00510462240.039
cellular divalent inorganic cation homeostasisGO:00725031620.038
cellular response to endogenous stimulusGO:00714953770.038
regulation of secretion by cellGO:19035302080.038
metal ion transportGO:00300012890.038
multi organism reproductive processGO:00447032620.038
atp synthesis coupled electron transportGO:004277320.037
regulation of cellular protein metabolic processGO:00322682670.037
nucleoside triphosphate metabolic processGO:00091411440.037
negative regulation of phosphate metabolic processGO:0045936800.037
response to light stimulusGO:0009416520.037
spindle organizationGO:000705120.036
regulation of catalytic activityGO:00507903040.036
ion transmembrane transportGO:00342203650.035
cellular ion homeostasisGO:00068731840.035
ribonucleoside monophosphate metabolic processGO:0009161880.035
cellular response to stressGO:00335542690.034
regulation of rna metabolic processGO:00512523910.034
atp metabolic processGO:0046034720.034
regulation of apoptotic processGO:00429813350.033
positive regulation of response to stimulusGO:00485842850.033
reproductive processGO:00224143720.032
regenerationGO:00310991630.032
adult locomotory behaviorGO:000834440.032
response to peptide hormoneGO:00434342780.032
thioester biosynthetic processGO:003538470.031
cellular calcium ion homeostasisGO:00068741600.031
cellular cation homeostasisGO:00300031800.031
regulation of protein phosphorylationGO:00019321830.030
cell projection morphogenesisGO:00488581230.030
positive regulation of biosynthetic processGO:00098913190.029
neuron apoptotic processGO:0051402880.029
regulation of ion transportGO:00432692450.029
response to radiationGO:00093141370.029
secretionGO:00469033070.028
regulation of intracellular signal transductionGO:19025312180.028
positive regulation of signalingGO:00230562700.028
regulation of programmed cell deathGO:00430673410.028
regulation of cell proliferationGO:00421273590.028
cellular amino acid metabolic processGO:00065201070.028
ribose phosphate metabolic processGO:00196932350.027
regulation of protein modification processGO:00313991940.027
positive regulation of cell deathGO:00109421840.027
response to nutrient levelsGO:00316673700.027
negative regulation of phosphorus metabolic processGO:0010563800.027
negative regulation of protein metabolic processGO:00512481140.027
response to cytokineGO:00340972150.027
positive regulation of multicellular organismal processGO:00512403870.026
regulation of cellular component organizationGO:00511283680.026
negative regulation of gene expressionGO:00106291990.026
aspartate family amino acid biosynthetic processGO:000906740.026
positive regulation of secretionGO:00510471400.026
cellular response to reactive oxygen speciesGO:0034614550.026
nucleoside monophosphate metabolic processGO:0009123930.025
cellular response to peptide hormone stimulusGO:00713751200.025
regulation of kinase activityGO:00435491170.025
regulation of membrane potentialGO:00423911100.024
cell cell signalingGO:00072673350.024
regulation of phosphorylationGO:00423252480.024
positive regulation of cellular protein metabolic processGO:00322701670.024
carbohydrate derivative metabolic processGO:19011353460.024
negative regulation of cell communicationGO:00106481580.024
regulation of nucleotide metabolic processGO:00061401170.024
calcium ion homeostasisGO:00550741620.023
negative regulation of macromolecule metabolic processGO:00106052600.023
cellular response to oxidative stressGO:0034599760.023
multicellular organismal reproductive processGO:00486092330.023
cardiovascular system developmentGO:00723581340.023
positive regulation of programmed cell deathGO:00430681570.023
macromolecular complex assemblyGO:00650032730.023
neurotransmitter uptakeGO:000150430.023
regulation of transferase activityGO:00513381230.023
negative regulation of catalytic activityGO:00430861030.023
response to monosaccharideGO:00342841590.022
divalent inorganic cation homeostasisGO:00725071650.022
intracellular signal transductionGO:00355563140.022
negative regulation of metabolic processGO:00098923310.022
regulation of nucleic acid templated transcriptionGO:19035063800.022
regulation of molecular functionGO:00650093980.022
regulation of cellular amino acid metabolic processGO:000652120.022
regulation of p38mapk cascadeGO:190074410.022
aerobic respirationGO:0009060130.022
centrosome organizationGO:005129710.021
negative regulation of cellular component organizationGO:0051129830.021
regulation of peptide transportGO:0090087870.021
fatty acid metabolic processGO:0006631990.021
positive regulation of cell communicationGO:00106472710.021
positive regulation of intracellular signal transductionGO:19025331380.021
regulation of anatomical structure morphogenesisGO:00226031410.021
regulation of cellular amine metabolic processGO:003323880.021
negative regulation of cellular biosynthetic processGO:00313271610.021
microtubule organizing center organizationGO:003102310.021
neuron deathGO:00709971270.020
response to bacteriumGO:00096172000.020
double strand break repairGO:000630210.020
positive regulation of dna recombinationGO:004591110.020
regulation of purine nucleotide metabolic processGO:19005421150.020
female pregnancyGO:00075651220.020
alpha amino acid metabolic processGO:1901605710.020
amide transportGO:00428861050.020
negative regulation of cellular metabolic processGO:00313242810.020
negative regulation of cellular protein metabolic processGO:00322691060.019
anatomical structure morphogenesisGO:00096532980.019
heart developmentGO:0007507720.019
response to hydrogen peroxideGO:0042542890.019
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.019
acetyl coa metabolic processGO:0006084170.018
positive regulation of cellular biosynthetic processGO:00313282950.018
cellular response to peptideGO:19016531330.018
response to extracellular stimulusGO:00099913800.018
response to transition metal nanoparticleGO:19902671220.018
positive regulation of hydrolase activityGO:0051345860.018
negative regulation of neurogenesisGO:0050768780.018
negative regulation of endopeptidase activityGO:0010951360.018
response to carbohydrateGO:00097431830.018
protein autophosphorylationGO:0046777660.017
negative regulation of transportGO:00510511360.017
regulation of hydrolase activityGO:00513361430.017
cellular response to organonitrogen compoundGO:00714171970.017
regulation of cellular localizationGO:00603412630.017
reproductionGO:00000032450.017
negative regulation of cell deathGO:00605482290.017
single organism intracellular transportGO:19025821660.016
organophosphate catabolic processGO:00464341480.016
glucose homeostasisGO:0042593750.016
rna metabolic processGO:00160704060.016
cell redox homeostasisGO:004545410.016
inflammatory responseGO:00069541500.016
carboxylic acid catabolic processGO:0046395490.016
regulation of multicellular organismal developmentGO:20000263760.016
calcium ion transportGO:00068161310.016
cation transmembrane transportGO:00986552630.016
small gtpase mediated signal transductionGO:0007264360.016
single organism behaviorGO:00447081300.016
cellular amide metabolic processGO:0043603440.016
divalent metal ion transportGO:00708381320.016
tissue developmentGO:00098882520.016
regulation of transcription dna templatedGO:00063553740.015
response to decreased oxygen levelsGO:00362932370.015
response to external biotic stimulusGO:00432072210.015
maternal process involved in female pregnancyGO:0060135380.015
cellular protein localizationGO:00346131220.015
cellular response to insulin stimulusGO:0032869810.015
nucleic acid transportGO:005065730.015
protein oligomerizationGO:00512591910.015
wnt signaling pathwayGO:0016055170.015
response to nutrientGO:00075842480.015
dephosphorylationGO:0016311980.015
cellular component biogenesisGO:00440853680.015
peptide transportGO:0015833970.015
macromolecular complex subunit organizationGO:00439333390.015
posttranscriptional regulation of gene expressionGO:0010608370.015
positive regulation of molecular functionGO:00440932300.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
monocarboxylic acid metabolic processGO:00327871520.014
positive regulation of developmental processGO:00510942830.014
intracellular transportGO:00469071850.014
neurological system processGO:00508772190.014
cellular response to nitrogen compoundGO:19016992100.014
positive regulation of protein metabolic processGO:00512471780.014
regulation of rna biosynthetic processGO:20011413810.014
response to activityGO:0014823730.014
response to reactive oxygen speciesGO:00003021200.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
central nervous system developmentGO:00074173110.014
protein complex assemblyGO:00064612630.014
negative regulation of phosphorylationGO:0042326570.014
single organism organelle organizationGO:19025891800.014
anion transportGO:00068201780.014
organic anion transportGO:00157111320.014
single organism reproductive processGO:00447022970.014
signal releaseGO:00230611450.013
cell part morphogenesisGO:00329901230.013
nucleic acid templated transcriptionGO:00976593790.013
amine metabolic processGO:0009308380.013
negative regulation of cell differentiationGO:0045596990.013
multicellular organism reproductionGO:00325042330.013
organ regenerationGO:00311001010.013
cellular amine metabolic processGO:0044106380.013
response to other organismGO:00517072200.013
positive regulation of ion transportGO:0043270940.013
cellular ketone metabolic processGO:0042180510.013
response to hypoxiaGO:00016662310.013
muscle system processGO:00030121150.013
anion transmembrane transportGO:0098656770.013
ras protein signal transductionGO:0007265290.012
nucleocytoplasmic transportGO:0006913480.012
positive regulation of immune system processGO:0002684900.012
response to glucocorticoidGO:00513842230.012
protein complex biogenesisGO:00702712630.012
cell projection organizationGO:00300303020.012
action potentialGO:0001508540.012
adenine nucleotide transportGO:005150320.012
positive regulation of nitrogen compound metabolic processGO:00511733340.012
regulation of anatomical structure sizeGO:00900661350.012
regulation of neurogenesisGO:00507672470.012
negative regulation of cell developmentGO:0010721820.012
sexual reproductionGO:00199531480.012
regulation of atp biosynthetic processGO:200116920.012
regulation of protein kinase activityGO:00458591050.012
cellular response to alcoholGO:0097306870.012
positive regulation of rna metabolic processGO:00512542030.012
organic hydroxy compound transportGO:0015850770.011
response to corticosteroidGO:00319602350.011
synaptic transmissionGO:00072682350.011
cellular response to carbohydrate stimulusGO:0071322720.011
negative regulation of cell cycle phase transitionGO:190198840.011
anatomical structure homeostasisGO:0060249290.011
response to biotic stimulusGO:00096072260.011
behaviorGO:00076102050.011
autophagic cell deathGO:004810240.011
response to growth factorGO:00708481890.011
cell adhesionGO:00071551100.011
response to toxic substanceGO:00096361330.011
programmed necrotic cell deathGO:009730020.011
transcription from rna polymerase ii promoterGO:00063662520.011
negative regulation of apoptotic processGO:00430661810.011
negative regulation of protein phosphorylationGO:0001933440.011
regulation of neuron projection developmentGO:00109751610.011
immune system processGO:00023762040.011
regulation of blood vessel endothelial cell migrationGO:004353540.011
rhythmic processGO:00485111560.011
necroptotic processGO:007026620.011
macromolecule localizationGO:00330362520.011
positive regulation of cell developmentGO:00107201760.010
cellular macromolecule localizationGO:00707271220.010
biological adhesionGO:00226101100.010
response to hexoseGO:00097461440.010
negative regulation of programmed cell deathGO:00430691830.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
chromosome segregationGO:000705920.010
response to glucoseGO:00097491360.010

Pdha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
amino acid metabolic disorderDOID:925200.291
disease of metabolismDOID:001466700.291
inherited metabolic disorderDOID:65500.291
organic acidemiaDOID:006015900.291
nervous system diseaseDOID:86300.057
disease of anatomical entityDOID:700.057
eye diseaseDOID:561400.019
eye and adnexa diseaseDOID:149200.019
sensory system diseaseDOID:005015500.019
retinal diseaseDOID:567900.013
maple syrup urine diseaseDOID:926900.011