Rattus norvegicus

54 known processes

Polb

polymerase (DNA directed), beta

Polb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of apoptotic processGO:00429813350.169
macromolecular complex subunit organizationGO:00439333390.156
macromolecular complex assemblyGO:00650032730.147
programmed cell deathGO:00125013920.133
apoptotic processGO:00069153810.132
cellular component biogenesisGO:00440853680.124
regulation of programmed cell deathGO:00430673410.112
organelle organizationGO:00069962660.109
cellular component assemblyGO:00226073600.106
protein complex subunit organizationGO:00718223020.104
protein complex assemblyGO:00064612630.097
negative regulation of cellular metabolic processGO:00313242810.095
protein complex biogenesisGO:00702712630.088
negative regulation of apoptotic processGO:00430661810.087
intracellular signal transductionGO:00355563140.087
macromolecule localizationGO:00330362520.083
rna metabolic processGO:00160704060.082
negative regulation of gene expressionGO:00106291990.074
positive regulation of transportGO:00510502450.073
response to oxygen levelsGO:00704822650.073
regulation of protein metabolic processGO:00512462890.071
negative regulation of programmed cell deathGO:00430691830.071
negative regulation of biosynthetic processGO:00098901680.070
negative regulation of cellular biosynthetic processGO:00313271610.070
rna biosynthetic processGO:00327743800.068
regulation of cellular localizationGO:00603412630.064
regulation of rna biosynthetic processGO:20011413810.063
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.062
negative regulation of cell deathGO:00605482290.061
negative regulation of metabolic processGO:00098923310.057
neurological system processGO:00508772190.055
regulation of cellular protein metabolic processGO:00322682670.054
single organism organelle organizationGO:19025891800.054
transcription from rna polymerase ii promoterGO:00063662520.054
regulation of multicellular organismal developmentGO:20000263760.054
protein phosphorylationGO:00064683450.053
establishment of protein localizationGO:00451841410.053
nucleic acid templated transcriptionGO:00976593790.053
oxoacid metabolic processGO:00434362900.051
negative regulation of nitrogen compound metabolic processGO:00511721610.051
regulation of signal transductionGO:00099663180.050
response to decreased oxygen levelsGO:00362932370.050
regulation of cell proliferationGO:00421273590.050
cellular response to oxygen containing compoundGO:19017013860.049
central nervous system developmentGO:00074173110.049
regulation of molecular functionGO:00650093980.049
cellular amino acid metabolic processGO:00065201070.048
negative regulation of signalingGO:00230571570.048
localization of cellGO:00516742020.046
single organism reproductive processGO:00447022970.046
organophosphate metabolic processGO:00196373700.046
negative regulation of macromolecule metabolic processGO:00106052600.046
transcription dna templatedGO:00063513770.045
positive regulation of nitrogen compound metabolic processGO:00511733340.044
negative regulation of transcription dna templatedGO:00458921160.044
reproductionGO:00000032450.044
secretionGO:00469033070.043
negative regulation of nucleic acid templated transcriptionGO:19035071170.042
multicellular organism reproductionGO:00325042330.042
neuron differentiationGO:00301823680.042
purine containing compound metabolic processGO:00725212530.042
regulation of phosphate metabolic processGO:00192203490.041
response to inorganic substanceGO:00100353770.041
nucleobase containing small molecule metabolic processGO:00550863160.041
regulation of nucleic acid templated transcriptionGO:19035063800.040
circulatory system developmentGO:00723591340.040
cell type specific apoptotic processGO:00972851340.039
multicellular organismal reproductive processGO:00486092330.039
response to nutrient levelsGO:00316673700.039
positive regulation of biosynthetic processGO:00098913190.038
regulation of transcription dna templatedGO:00063553740.038
regulation of protein localizationGO:0032880810.038
cellular component movementGO:00069282480.038
positive regulation of cell proliferationGO:00082842490.037
intracellular transportGO:00469071850.037
negative regulation of rna metabolic processGO:00512531230.036
secretion by cellGO:00329402480.036
regulation of cellular ketone metabolic processGO:0010565270.036
catabolic processGO:00090563510.036
positive regulation of programmed cell deathGO:00430681570.036
protein oligomerizationGO:00512591910.035
nucleoside phosphate metabolic processGO:00067532830.035
regulation of cellular component organizationGO:00511283680.035
regulation of cellular amino acid metabolic processGO:000652120.035
positive regulation of developmental processGO:00510942830.035
organic substance catabolic processGO:19015753160.035
positive regulation of cell deathGO:00109421840.035
agingGO:00075682410.034
response to bacteriumGO:00096172000.034
developmental process involved in reproductionGO:00030061590.034
carboxylic acid metabolic processGO:00197522890.034
positive regulation of cellular protein metabolic processGO:00322701670.034
cardiovascular system developmentGO:00723581340.033
cell migrationGO:00164771970.033
positive regulation of multicellular organismal processGO:00512403870.033
cellular response to endogenous stimulusGO:00714953770.033
response to estrogenGO:00436272320.033
response to peptideGO:19016522920.033
amine metabolic processGO:0009308380.033
reproductive processGO:00224143720.033
cellular catabolic processGO:00442482950.033
axis specificationGO:000979840.032
response to lipopolysaccharideGO:00324961910.032
positive regulation of apoptotic processGO:00430651540.032
negative regulation of macromolecule biosynthetic processGO:00105581480.032
regulation of phosphorylationGO:00423252480.032
positive regulation of cellular component organizationGO:00511302000.032
cellular protein localizationGO:00346131220.032
chromosome segregationGO:000705920.031
response to woundingGO:00096112540.031
homeostatic processGO:00425923310.031
sexual reproductionGO:00199531480.031
response to temperature stimulusGO:0009266940.031
negative regulation of rna biosynthetic processGO:19026791180.031
cellular macromolecule localizationGO:00707271220.030
cellular response to organic cyclic compoundGO:00714072020.030
behaviorGO:00076102050.030
brain developmentGO:00074202470.030
locomotionGO:00400112370.029
regulation of protein transportGO:0051223680.029
cellular lipid metabolic processGO:00442552080.029
positive regulation of cell communicationGO:00106472710.029
protein transportGO:00150311320.029
cellular response to stressGO:00335542690.029
response to hypoxiaGO:00016662310.029
positive regulation of gene expressionGO:00106282440.029
regulation of intracellular signal transductionGO:19025312180.029
response to cytokineGO:00340972150.029
organic acid metabolic processGO:00060822920.028
regulation of transcription from rna polymerase ii promoterGO:00063572340.028
neuron projection developmentGO:00311752730.028
growthGO:00400071650.028
negative regulation of nucleobase containing compound metabolic processGO:00459341530.028
anterior posterior pattern specificationGO:000995210.028
regulation of rna metabolic processGO:00512523910.028
response to glucocorticoidGO:00513842230.028
carbohydrate derivative metabolic processGO:19011353460.028
cell cycleGO:00070491010.027
regulation of secretionGO:00510462240.027
response to insulinGO:00328681330.027
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.027
anatomical structure morphogenesisGO:00096532980.027
response to ethanolGO:00454711620.027
purine ribonucleotide metabolic processGO:00091502270.027
cellular amine metabolic processGO:0044106380.027
regulation of cell cycleGO:0051726730.027
response to toxic substanceGO:00096361330.027
ribonucleotide metabolic processGO:00092592310.027
response to peptide hormoneGO:00434342780.027
single organism catabolic processGO:00447122830.027
regulation of catalytic activityGO:00507903040.027
regulation of cell migrationGO:00303341280.027
positive regulation of protein metabolic processGO:00512471780.027
response to biotic stimulusGO:00096072260.027
regulation of phosphorus metabolic processGO:00511743490.026
response to extracellular stimulusGO:00099913800.026
cell motilityGO:00488702020.026
cytoskeleton organizationGO:00070101110.026
positive regulation of molecular functionGO:00440932300.026
regulation of neuron apoptotic processGO:0043523830.026
neuron apoptotic processGO:0051402880.026
response to glucoseGO:00097491360.025
rhythmic processGO:00485111560.025
positive regulation of response to stimulusGO:00485842850.025
learning or memoryGO:0007611900.025
positive regulation of cellular biosynthetic processGO:00313282950.025
regulation of protein modification processGO:00313991940.025
response to radiationGO:00093141370.025
cellular response to hormone stimulusGO:00328702470.025
purine ribonucleotide biosynthetic processGO:0009152810.024
ribonucleoside metabolic processGO:00091191740.024
neuron developmentGO:00486662860.024
response to nutrientGO:00075842480.024
regulation of cell differentiationGO:00455953200.024
purine nucleotide metabolic processGO:00061632290.024
cellular ketone metabolic processGO:0042180510.024
response to metal ionGO:00100382530.023
response to growth factorGO:00708481890.023
synaptic transmissionGO:00072682350.023
regulation of neuron deathGO:19012141150.023
ribose phosphate metabolic processGO:00196932350.023
response to hydrogen peroxideGO:0042542890.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
cell growthGO:00160491040.023
negative regulation of signal transductionGO:0009968830.023
regulation of cellular amine metabolic processGO:003323880.023
cell cell signalingGO:00072673350.022
peptidyl amino acid modificationGO:00181931260.022
tissue developmentGO:00098882520.022
nucleoside monophosphate metabolic processGO:0009123930.022
head developmentGO:00603222470.021
lipid metabolic processGO:00066292830.021
single organism biosynthetic processGO:00447113420.021
heterocycle catabolic processGO:00467001670.021
response to other organismGO:00517072200.021
dephosphorylationGO:0016311980.021
spindle organizationGO:000705120.021
single organism intracellular transportGO:19025821660.021
negative regulation of response to stimulusGO:00485851550.020
axon developmentGO:0061564960.020
positive regulation of phosphorus metabolic processGO:00105622620.020
nucleotide metabolic processGO:00091172790.020
positive regulation of locomotionGO:00400171020.020
negative regulation of cell communicationGO:00106481580.020
cytoplasmic transportGO:00164821150.020
regulation of secretion by cellGO:19035302080.020
cell cycle checkpointGO:000007520.020
response to external biotic stimulusGO:00432072210.020
response to reactive oxygen speciesGO:00003021200.020
gamete generationGO:00072761240.020
negative regulation of mitotic cell cycle phase transitionGO:190199130.020
nucleoside catabolic processGO:00091641260.020
regulation of anatomical structure sizeGO:00900661350.019
multi organism reproductive processGO:00447032620.019
response to heatGO:0009408600.019
regulation of lipid metabolic processGO:0019216680.019
response to molecule of bacterial originGO:00022371940.019
positive regulation of signalingGO:00230562700.019
proteolysisGO:00065081750.019
glycosyl compound metabolic processGO:19016571820.019
establishment of organelle localizationGO:0051656370.019
purine nucleoside triphosphate metabolic processGO:00091441410.019
actin filament based processGO:0030029860.019
embryonic pattern specificationGO:000988010.019
response to estradiolGO:00323551640.019
muscle system processGO:00030121150.019
spermatogenesisGO:0007283990.018
cellular nitrogen compound catabolic processGO:00442701630.018
negative regulation of molecular functionGO:00440921330.018
regulation of protein phosphorylationGO:00019321830.018
apoptotic signaling pathwayGO:0097190270.018
regulation of establishment of protein localizationGO:0070201690.018
multicellular organism growthGO:003526410.018
positive regulation of cellular component movementGO:00512721020.018
regulation of cellular component movementGO:00512701500.018
response to acid chemicalGO:00011012220.018
protein localizationGO:00081041910.018
regulation of cell developmentGO:00602842630.018
cellular response to abiotic stimulusGO:0071214850.018
defense responseGO:00069521940.018
single organism cellular localizationGO:19025801020.017
negative regulation of cellular protein metabolic processGO:00322691060.017
negative regulation of cell cycle phase transitionGO:190198840.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
small gtpase mediated signal transductionGO:0007264360.017
positive regulation of macromolecule biosynthetic processGO:00105572470.017
neuron deathGO:00709971270.017
regulation of neurogenesisGO:00507672470.017
synaptic growth at neuromuscular junctionGO:005112410.017
negative regulation of cell proliferationGO:00082851190.017
reproductive structure developmentGO:00486081280.017
ribose phosphate biosynthetic processGO:0046390870.017
embryonic skeletal system developmentGO:004870630.017
regulation of locomotionGO:00400121480.017
cellular response to lipidGO:00713962010.017
regulation of membrane potentialGO:00423911100.017
positive regulation of phosphorylationGO:00423271770.017
immune system processGO:00023762040.017
muscle structure developmentGO:0061061870.017
purine nucleoside metabolic processGO:00422781690.017
cognitionGO:0050890920.017
regulation of anatomical structure morphogenesisGO:00226031410.016
regulation of system processGO:00440572080.016
nuclear transportGO:0051169490.016
ras protein signal transductionGO:0007265290.016
single organism behaviorGO:00447081300.016
response to corticosteroidGO:00319602350.016
g protein coupled receptor signaling pathwayGO:00071862420.016
negative regulation of transportGO:00510511360.016
negative regulation of multicellular organismal processGO:00512412030.016
endocytosisGO:0006897840.016
organic cyclic compound catabolic processGO:19013611750.016
positive regulation of secretion by cellGO:19035321280.016
cellular response to growth factor stimulusGO:00713631620.016
nucleotide biosynthetic processGO:0009165980.016
cellular response to organonitrogen compoundGO:00714171970.016
cell projection organizationGO:00300303020.016
nucleoside phosphate biosynthetic processGO:19012931020.016
cell part morphogenesisGO:00329901230.015
vesicle mediated transportGO:00161921810.015
positive regulation of protein modification processGO:00314011420.015
regulation of hydrolase activityGO:00513361430.015
cellular response to external stimulusGO:00714961180.015
purine ribonucleoside monophosphate metabolic processGO:0009167840.015
purine ribonucleoside metabolic processGO:00461281680.015
membrane organizationGO:0061024940.015
sex differentiationGO:00075481130.015
regulation of proteolysisGO:0030162660.015
positive regulation of cell migrationGO:0030335960.015
embryonic axis specificationGO:000057810.015
development of primary sexual characteristicsGO:00451371070.015
nucleoside triphosphate metabolic processGO:00091411440.015
positive regulation of secretionGO:00510471400.015
response to alkaloidGO:00432791320.014
response to oxidative stressGO:00069791860.014
nucleotide catabolic processGO:00091661390.014
cellular response to insulin stimulusGO:0032869810.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
nucleobase containing compound catabolic processGO:00346551520.014
positive regulation of cell projection organizationGO:00313461110.014
reproductive system developmentGO:00614581280.014
negative regulation of protein metabolic processGO:00512481140.014
circulatory system processGO:00030131830.014
positive regulation of cell motilityGO:2000147970.014
monocarboxylic acid metabolic processGO:00327871520.014
nucleoside metabolic processGO:00091161790.014
regulation of cellular component biogenesisGO:0044087860.014
protein maturationGO:0051604680.014
regulation of response to external stimulusGO:00321011060.014
cell projection morphogenesisGO:00488581230.014
negative regulation of neuron apoptotic processGO:0043524450.014
carbohydrate derivative biosynthetic processGO:19011371240.014
regulation of mapk cascadeGO:00434081160.013
cation transportGO:00068123820.013
cytoskeleton dependent cytokinesisGO:006164020.013
tube developmentGO:0035295890.013
regulation of cell motilityGO:20001451310.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
dna metabolic processGO:0006259960.013
positive regulation of cellular amine metabolic processGO:003324030.013
inflammatory responseGO:00069541500.013
muscle contractionGO:0006936880.013
peptide secretionGO:0002790860.013
protein heterooligomerizationGO:0051291890.013
response to transition metal nanoparticleGO:19902671220.013
blood circulationGO:00080151830.013
eye morphogenesisGO:004859240.013
positive regulation of signal transductionGO:00099671750.013
intracellular protein transportGO:0006886790.013
purine nucleoside monophosphate metabolic processGO:0009126840.013
regulation of cell projection organizationGO:00313441750.013
oxidation reduction processGO:00551143040.013
response to monosaccharideGO:00342841590.013
actin cytoskeleton organizationGO:0030036730.013
single organism carbohydrate metabolic processGO:00447231180.012
gastrulationGO:000736920.012
mitotic cell cycle checkpointGO:000709310.012
positive regulation of protein transportGO:0051222410.012
purine nucleotide catabolic processGO:00061951360.012
regulation of hormone levelsGO:00108171870.012
positive regulation of rna metabolic processGO:00512542030.012
positive regulation of cell differentiationGO:00455972170.012
negative regulation of catalytic activityGO:00430861030.012
male gamete generationGO:0048232990.012
aromatic compound catabolic processGO:00194391680.012
ovulation cycleGO:0042698670.012
signal releaseGO:00230611450.012
response to antibioticGO:0046677390.012
regulation of vesicle mediated transportGO:0060627810.012
response to carbohydrateGO:00097431830.012
protein processingGO:0016485680.012
nitrogen compound transportGO:00717052290.012
cellular response to peptide hormone stimulusGO:00713751200.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
positive regulation of catalytic activityGO:00430851840.012
regulation of actin filament based processGO:0032970420.012
purine ribonucleotide catabolic processGO:00091541360.011
organonitrogen compound biosynthetic processGO:19015661670.011
organophosphate biosynthetic processGO:00904071430.011
dna integrity checkpointGO:003157020.011
maintenance of locationGO:0051235170.011
cell morphogenesisGO:00009021420.011
regulation of protein processingGO:0070613500.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
chemical homeostasisGO:00488782920.011
negative regulation of developmental processGO:00510931250.011
purine containing compound biosynthetic processGO:0072522850.011
metal ion transportGO:00300012890.011
mitotic cell cycleGO:0000278490.011
ribonucleotide biosynthetic processGO:0009260850.011
negative regulation of neuron deathGO:1901215690.011
positive regulation of phosphate metabolic processGO:00459372620.011
reactive oxygen species metabolic processGO:0072593370.011
ion transmembrane transportGO:00342203650.011
mitotic spindle organizationGO:000705220.011
regulation of cellular component sizeGO:0032535510.011
cellular carbohydrate metabolic processGO:0044262720.011
regulation of nervous system developmentGO:00519602640.011
positive regulation of organelle organizationGO:0010638480.011
regulation of catabolic processGO:00098941130.011
cell morphogenesis involved in differentiationGO:00009041190.011
positive regulation of nervous system developmentGO:00519621780.011
striated muscle contractionGO:0006941440.011
regulation of cytokine biosynthetic processGO:004203530.011
nucleocytoplasmic transportGO:0006913480.011
lipid biosynthetic processGO:00086101280.011
response to light stimulusGO:0009416520.011
organelle localizationGO:0051640550.011
positive regulation of protein phosphorylationGO:00019341350.011
regulation of cell growthGO:0001558850.011
regulation of epithelial cell proliferationGO:0050678490.011
single organism membrane organizationGO:0044802740.010
organophosphate catabolic processGO:00464341480.010
eye developmentGO:0001654500.010
response to vitaminGO:00332731310.010
glycosyl compound catabolic processGO:19016581260.010
regulation of ion transportGO:00432692450.010
striated muscle tissue developmentGO:0014706580.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
response to amino acidGO:0043200750.010
regulation of smooth muscle cell proliferationGO:0048660750.010

Polb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.012
organ system cancerDOID:005068600.012
sensory system diseaseDOID:005015500.012