Rattus norvegicus

30 known processes

Aurkb

aurora kinase B

(Aliases: Stk12,Aim1)

Aurkb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component biogenesisGO:00440853680.129
Human Fly
negative regulation of metabolic processGO:00098923310.094
Human
cell cycleGO:00070491010.090
negative regulation of macromolecule metabolic processGO:00106052600.082
Human
single organism reproductive processGO:00447022970.080
Fly
regulation of cellular component organizationGO:00511283680.079
Human
protein phosphorylationGO:00064683450.076
protein complex biogenesisGO:00702712630.073
Human Fly
chromosome segregationGO:000705920.071
Fly
protein complex subunit organizationGO:00718223020.071
Human Fly
regulation of cell proliferationGO:00421273590.069
meiotic cell cycle processGO:190304630.067
organic cyclic compound catabolic processGO:19013611750.065
catabolic processGO:00090563510.065
cell cycle checkpointGO:000007520.064
positive regulation of nitrogen compound metabolic processGO:00511733340.064
dna packagingGO:000632340.062
Fly
negative regulation of gene expressionGO:00106291990.061
Human
meiosis iGO:000712720.060
developmental process involved in reproductionGO:00030061590.059
Fly
male meiosisGO:000714010.059
regulation of rna biosynthetic processGO:20011413810.058
Human
reproductive processGO:00224143720.056
Fly
cellular catabolic processGO:00442482950.055
multicellular organism reproductionGO:00325042330.053
Fly
cellular component movementGO:00069282480.053
anatomical structure morphogenesisGO:00096532980.053
Fly
cellular component assemblyGO:00226073600.049
Human Fly
negative regulation of cellular metabolic processGO:00313242810.048
Human
transcription dna templatedGO:00063513770.047
Human
apoptotic processGO:00069153810.047
Human
organic substance catabolic processGO:19015753160.047
negative regulation of mitotic cell cycle phase transitionGO:190199130.045
rna metabolic processGO:00160704060.045
Human
organophosphate metabolic processGO:00196373700.045
reproductionGO:00000032450.044
Fly
negative regulation of nitrogen compound metabolic processGO:00511721610.044
Human
response to hypoxiaGO:00016662310.044
multi organism reproductive processGO:00447032620.042
Fly
regulation of molecular functionGO:00650093980.042
Human
reproductive system developmentGO:00614581280.042
rna biosynthetic processGO:00327743800.041
Human
regulation of cell differentiationGO:00455953200.041
Fly
nucleobase containing small molecule metabolic processGO:00550863160.039
protein complex assemblyGO:00064612630.039
Human Fly
regulation of multicellular organismal developmentGO:20000263760.039
Fly
negative regulation of cellular biosynthetic processGO:00313271610.039
Human
purine ribonucleotide metabolic processGO:00091502270.039
regulation of rna metabolic processGO:00512523910.039
Human
heterocycle catabolic processGO:00467001670.039
cellular nitrogen compound catabolic processGO:00442701630.038
nucleic acid templated transcriptionGO:00976593790.038
Human
regulation of catalytic activityGO:00507903040.038
negative regulation of cell cycle phase transitionGO:190198840.037
spindle organizationGO:000705120.037
Human Fly
macromolecule catabolic processGO:0009057580.037
carbohydrate derivative metabolic processGO:19011353460.037
lipid metabolic processGO:00066292830.036
positive regulation of macromolecule biosynthetic processGO:00105572470.036
agingGO:00075682410.036
cellular response to oxygen containing compoundGO:19017013860.036
rhythmic processGO:00485111560.035
positive regulation of developmental processGO:00510942830.035
protein localization to chromosome centromeric regionGO:007145910.034
Human
organic acid metabolic processGO:00060822920.034
response to ethanolGO:00454711620.034
negative regulation of rna biosynthetic processGO:19026791180.034
Human
negative regulation of transcription dna templatedGO:00458921160.034
Human
single organism catabolic processGO:00447122830.034
response to oxygen levelsGO:00704822650.033
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.033
Human
positive regulation of biosynthetic processGO:00098913190.033
reproductive structure developmentGO:00486081280.033
regulation of transcription dna templatedGO:00063553740.033
Human
macromolecular complex assemblyGO:00650032730.032
Human Fly
negative regulation of cell deathGO:00605482290.032
Human
cell projection organizationGO:00300303020.032
macromolecular complex subunit organizationGO:00439333390.032
Human Mouse Fly
single organism biosynthetic processGO:00447113420.032
regulation of protein metabolic processGO:00512462890.032
macromolecule localizationGO:00330362520.032
Human Fly
double strand break repairGO:000630210.032
nucleotide catabolic processGO:00091661390.032
organophosphate catabolic processGO:00464341480.031
growthGO:00400071650.031
chromosome condensationGO:003026130.031
Fly
oxoacid metabolic processGO:00434362900.031
programmed cell deathGO:00125013920.031
Human
regulation of phosphorus metabolic processGO:00511743490.031
multicellular organismal reproductive processGO:00486092330.031
Fly
regulation of phosphate metabolic processGO:00192203490.031
intracellular transportGO:00469071850.031
nucleobase containing compound catabolic processGO:00346551520.031
regulation of nervous system developmentGO:00519602640.030
Fly
carboxylic acid metabolic processGO:00197522890.030
neuron differentiationGO:00301823680.030
response to oxidative stressGO:00069791860.030
organonitrogen compound catabolic processGO:19015651790.030
spermatogenesisGO:0007283990.030
response to peptide hormoneGO:00434342780.030
negative regulation of nucleobase containing compound metabolic processGO:00459341530.029
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.029
Human
mitotic spindle organizationGO:000705220.029
Human Fly
positive regulation of multicellular organismal processGO:00512403870.028
cellular response to endogenous stimulusGO:00714953770.028
cellular response to stressGO:00335542690.028
regulation of synapse maturationGO:009012820.028
metaphase anaphase transition of mitotic cell cycleGO:000709110.028
cellular amino acid metabolic processGO:00065201070.028
regulation of catabolic processGO:00098941130.027
nucleoside phosphate metabolic processGO:00067532830.027
regulation of apoptotic processGO:00429813350.027
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.027
Human
regulation of phosphorylationGO:00423252480.026
positive regulation of molecular functionGO:00440932300.026
regulation of cellular protein metabolic processGO:00322682670.026
negative regulation of chromosome organizationGO:200125110.026
purine containing compound metabolic processGO:00725212530.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
positive regulation of cell proliferationGO:00082842490.025
response to metal ionGO:00100382530.025
nucleotide metabolic processGO:00091172790.025
positive regulation of cellular biosynthetic processGO:00313282950.025
nucleoside monophosphate metabolic processGO:0009123930.025
mitotic sister chromatid segregationGO:000007010.025
Fly
positive regulation of cellular component organizationGO:00511302000.025
regulation of cell growthGO:0001558850.025
proteolysisGO:00065081750.024
protein localizationGO:00081041910.024
Human Fly
regulation of nucleic acid templated transcriptionGO:19035063800.024
Human
positive regulation of gene expressionGO:00106282440.024
response to peptideGO:19016522920.024
tissue developmentGO:00098882520.024
negative regulation of biosynthetic processGO:00098901680.024
Human
central nervous system developmentGO:00074173110.024
positive regulation of rna metabolic processGO:00512542030.023
response to external biotic stimulusGO:00432072210.023
ribose phosphate metabolic processGO:00196932350.023
mitotic sister chromatid separationGO:005130610.023
aromatic compound catabolic processGO:00194391680.023
transcription from rna polymerase ii promoterGO:00063662520.023
Human
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
purine nucleoside monophosphate catabolic processGO:0009128550.022
cellular amine metabolic processGO:0044106380.022
positive regulation of protein modification processGO:00314011420.022
regulation of cell developmentGO:00602842630.022
Fly
metaphase anaphase transition of cell cycleGO:004478410.022
positive regulation of catabolic processGO:0009896780.022
male gamete generationGO:0048232990.022
carbohydrate derivative catabolic processGO:19011361470.022
ribonucleotide metabolic processGO:00092592310.021
cellular response to hormone stimulusGO:00328702470.021
purine ribonucleoside monophosphate metabolic processGO:0009167840.021
regulation of growthGO:00400081050.021
sex differentiationGO:00075481130.021
vesicle mediated transportGO:00161921810.021
regulation of signal transductionGO:00099663180.021
negative regulation of programmed cell deathGO:00430691830.020
Human
gamete generationGO:00072761240.020
Fly
regenerationGO:00310991630.020
regulation of neurogenesisGO:00507672470.020
Fly
positive regulation of cellular protein metabolic processGO:00322701670.020
purine nucleotide metabolic processGO:00061632290.020
response to estrogenGO:00436272320.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
Human
organelle organizationGO:00069962660.020
Human Mouse Fly
response to corticosteroidGO:00319602350.020
positive regulation of triglyceride metabolic processGO:009020840.020
response to toxic substanceGO:00096361330.019
positive regulation of catalytic activityGO:00430851840.019
dna metabolic processGO:0006259960.019
Fly
response to insulinGO:00328681330.019
positive regulation of synapse maturationGO:009012920.019
protein catabolic processGO:0030163300.019
neuron developmentGO:00486662860.019
cellular component morphogenesisGO:00329891550.019
response to decreased oxygen levelsGO:00362932370.019
cerebellar purkinje cell layer morphogenesisGO:002169210.019
head developmentGO:00603222470.019
amine metabolic processGO:0009308380.019
regulation of meiotic cell cycleGO:005144530.018
single organism organelle organizationGO:19025891800.018
Human Mouse Fly
anatomical structure formation involved in morphogenesisGO:0048646830.018
Fly
response to organophosphorusGO:00466831020.018
negative regulation of apoptotic processGO:00430661810.018
Human
development of primary sexual characteristicsGO:00451371070.018
negative regulation of cellular protein metabolic processGO:00322691060.018
negative regulation of protein metabolic processGO:00512481140.018
cell growthGO:00160491040.018
cerebellar purkinje cell layer developmentGO:002168020.018
regulation of programmed cell deathGO:00430673410.017
Human
mitotic cell cycle checkpointGO:000709310.017
negative regulation of cell communicationGO:00106481580.017
sexual reproductionGO:00199531480.017
Fly
cytokinetic processGO:003250610.017
ribonucleoside metabolic processGO:00091191740.017
response to woundingGO:00096112540.017
ras protein signal transductionGO:0007265290.017
nucleoside phosphate catabolic processGO:19012921400.017
response to extracellular stimulusGO:00099913800.017
glycosyl compound catabolic processGO:19016581260.016
establishment of protein localizationGO:00451841410.016
regulation of cellular catabolic processGO:00313291010.016
positive regulation of growthGO:0045927550.016
negative regulation of nuclear divisionGO:005178410.016
response to biotic stimulusGO:00096072260.016
triglyceride metabolic processGO:0006641210.016
cellular response to nitrogen compoundGO:19016992100.016
small gtpase mediated signal transductionGO:0007264360.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
cellular protein localizationGO:00346131220.016
Human
cellular macromolecule localizationGO:00707271220.016
Human
protein maturationGO:0051604680.016
ribonucleotide catabolic processGO:00092611360.016
positive regulation of transcription dna templatedGO:00458931970.015
positive regulation of cellular amine metabolic processGO:003324030.015
gonad developmentGO:00084061040.015
regulation of chromosome segregationGO:005198310.015
epithelium developmentGO:0060429960.015
brain developmentGO:00074202470.015
protein oligomerizationGO:00512591910.015
cell cell signalingGO:00072673350.015
nucleoside triphosphate catabolic processGO:00091431230.015
regulation of mitotic sister chromatid separationGO:001096510.015
positive regulation of lipid catabolic processGO:005099640.015
nucleotide biosynthetic processGO:0009165980.015
ribonucleoside catabolic processGO:00424541260.015
regulation of cellular ketone metabolic processGO:0010565270.015
regulation of cellular amino acid metabolic processGO:000652120.015
negative regulation of rna metabolic processGO:00512531230.015
Human
positive regulation of cellular catabolic processGO:0031331710.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
regulation of cellular amine metabolic processGO:003323880.014
nucleoside triphosphate metabolic processGO:00091411440.014
cell cycle dna replicationGO:004478610.014
purine nucleoside catabolic processGO:00061521240.014
response to nutrient levelsGO:00316673700.014
negative regulation of signalingGO:00230571570.014
intracellular signal transductionGO:00355563140.014
carbohydrate derivative biosynthetic processGO:19011371240.014
purine ribonucleoside metabolic processGO:00461281680.014
single organism intracellular transportGO:19025821660.014
glycerolipid metabolic processGO:0046486670.014
positive regulation of phosphorus metabolic processGO:00105622620.014
response to reactive oxygen speciesGO:00003021200.014
neuron projection developmentGO:00311752730.014
regulation of cellular localizationGO:00603412630.014
nucleoside metabolic processGO:00091161790.014
purine nucleoside metabolic processGO:00422781690.014
centrosome cycleGO:000709810.014
Fly
synaptic transmissionGO:00072682350.014
positive regulation of phosphate metabolic processGO:00459372620.014
glycosyl compound metabolic processGO:19016571820.014
purine ribonucleoside monophosphate catabolic processGO:0009169550.014
cell morphogenesisGO:00009021420.014
circadian rhythmGO:0007623880.013
axis specificationGO:000979840.013
cytoplasmic transportGO:00164821150.013
response to transition metal nanoparticleGO:19902671220.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
regulation of mitotic sister chromatid segregationGO:003304710.013
negative regulation of molecular functionGO:00440921330.013
Human
chromosome separationGO:005130410.013
purine containing compound catabolic processGO:00725231380.013
protein processingGO:0016485680.013
peptidyl amino acid modificationGO:00181931260.013
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.013
sensory organ developmentGO:0007423740.013
intracellular protein transportGO:0006886790.013
negative regulation of cell proliferationGO:00082851190.013
cellular ketone metabolic processGO:0042180510.013
positive regulation of cell differentiationGO:00455972170.012
organophosphate biosynthetic processGO:00904071430.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
protein targetingGO:0006605610.012
response to glucocorticoidGO:00513842230.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
regulation of protein modification processGO:00313991940.012
cellular response to insulin stimulusGO:0032869810.012
nucleoside catabolic processGO:00091641260.012
cell part morphogenesisGO:00329901230.012
dna integrity checkpointGO:003157020.012
response to cadmium ionGO:0046686350.012
regulation of sister chromatid segregationGO:003304510.012
purine nucleoside monophosphate metabolic processGO:0009126840.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114510.012
response to bacteriumGO:00096172000.012
cellular response to reactive oxygen speciesGO:0034614550.012
cilium morphogenesisGO:006027120.012
homeostatic processGO:00425923310.012
regulation of transferase activityGO:00513381230.012
response to campGO:0051591910.012
regulation of proteolysisGO:0030162660.012
ribonucleoside triphosphate catabolic processGO:00092031220.012
positive regulation of cardiac muscle cell proliferationGO:006004540.011
regulation of cell projection organizationGO:00313441750.011
positive regulation of transportGO:00510502450.011
chromosome organizationGO:0051276360.011
Mouse Fly
positive regulation of synaptic plasticityGO:003191530.011
atp metabolic processGO:0046034720.011
neurological system processGO:00508772190.011
mitotic cell cycleGO:0000278490.011
Human Fly
cerebellar cortex formationGO:002169720.011
positive regulation of protein metabolic processGO:00512471780.011
tetrahydrofolate metabolic processGO:004665390.011
negative regulation of response to stimulusGO:00485851550.011
positive regulation of proteasomal protein catabolic processGO:190180030.011
actin filament based processGO:0030029860.011
microtubule organizing center organizationGO:003102310.011
Fly
regulation of neuron projection developmentGO:00109751610.011
nucleoside phosphate biosynthetic processGO:19012931020.011
pyrimidine nucleobase metabolic processGO:000620680.011
regulation of kinase activityGO:00435491170.011
dephosphorylationGO:0016311980.011
regulation of hydrolase activityGO:00513361430.011
positive regulation of dna metabolic processGO:0051054390.011
cardiovascular system developmentGO:00723581340.011
epithelial cell differentiationGO:0030855710.010
centrosome organizationGO:005129710.010
Fly
histone serine phosphorylationGO:003540410.010
Mouse
response to ketoneGO:19016541820.010
regulation of membrane potentialGO:00423911100.010
muscle cell differentiationGO:0042692520.010
positive regulation of phosphorylationGO:00423271770.010
protein localization to organelleGO:0033365570.010
Human
ribonucleoside monophosphate metabolic processGO:0009161880.010
metaphase plate congressionGO:005131010.010
microtubule anchoringGO:003445310.010
positive regulation of nervous system developmentGO:00519621780.010
regulation of organelle organizationGO:0033043800.010
Human
response to nutrientGO:00075842480.010
regulation of proteasomal protein catabolic processGO:006113640.010
protein transportGO:00150311320.010

Aurkb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.010
colorectal cancerDOID:925600.010
organ system cancerDOID:005068600.010
cancerDOID:16200.010
large intestine cancerDOID:567200.010
gastrointestinal system cancerDOID:311900.010
colon cancerDOID:21900.010
intestinal cancerDOID:1015500.010