IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Stip1

stress-induced phosphoprotein 1

Ensembl: ENSRNOG00000021164
Entrez: 192277
RGD: 621599
UniProtKB: O35814

Process Predictions
Disease Predictions

Stip1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein refolding	GO:0042026	3	1.000
chaperone mediated protein folding	GO:0061077	6	0.993
positive regulation of intracellular protein transport	GO:0090316	20	0.951
positive regulation of protein import into nucleus translocation	GO:0033160	7	0.912
positive regulation of protein binding	GO:0032092	9	0.899
positive regulation of nucleocytoplasmic transport	GO:0046824	17	0.874
de novo posttranslational protein folding	GO:0051084	2	0.869
response to heat	GO:0009408	60	0.849
chaperone mediated protein folding requiring cofactor	GO:0051085	2	0.843
macromolecule localization	GO:0033036	252	0.634
protein localization	GO:0008104	191	0.624
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.621	Yeast
protein complex subunit organization	GO:0071822	302	0.613
regulation of cardiac muscle contraction	GO:0055117	17	0.602
regulation of protein metabolic process	GO:0051246	289	0.584
protein transport	GO:0015031	132	0.581
protein folding	GO:0006457	12	0.559	Yeast
establishment of protein localization to organelle	GO:0072594	44	0.532
protein import	GO:0017038	37	0.508
de novo protein folding	GO:0006458	2	0.507
macromolecular complex subunit organization	GO:0043933	339	0.503
negative regulation of cellular metabolic process	GO:0031324	281	0.499
protein targeting	GO:0006605	61	0.492
positive regulation of multicellular organismal process	GO:0051240	387	0.448
programmed cell death	GO:0012501	392	0.437
regulation of programmed cell death	GO:0043067	341	0.434
nucleoside monophosphate metabolic process	GO:0009123	93	0.433	Yeast
cellular component assembly	GO:0022607	360	0.429
response to temperature stimulus	GO:0009266	94	0.414
positive regulation of cardiac muscle contraction	GO:0060452	4	0.411
detection of stimulus	GO:0051606	24	0.399
regulation of apoptotic process	GO:0042981	335	0.395
organelle organization	GO:0006996	266	0.389
single organism organelle organization	GO:1902589	180	0.388
single organism intracellular transport	GO:1902582	166	0.385
apoptotic process	GO:0006915	381	0.385
single organism nuclear import	GO:1902593	35	0.383
cell type specific apoptotic process	GO:0097285	134	0.380
protein import into nucleus	GO:0006606	35	0.374
cellular component biogenesis	GO:0044085	368	0.373
intracellular protein transport	GO:0006886	79	0.367
negative regulation of cell death	GO:0060548	229	0.359
positive regulation of protein localization to nucleus	GO:1900182	15	0.358
negative regulation of apoptotic process	GO:0043066	181	0.347
establishment of protein localization	GO:0045184	141	0.343
positive regulation of rna metabolic process	GO:0051254	203	0.342
organic substance catabolic process	GO:1901575	316	0.337	Yeast
nucleoside catabolic process	GO:0009164	126	0.323	Yeast
regulation of cellular component organization	GO:0051128	368	0.320
nuclear transport	GO:0051169	49	0.317
microtubule polymerization or depolymerization	GO:0031109	13	0.314
protein complex assembly	GO:0006461	263	0.313
macromolecular complex assembly	GO:0065003	273	0.307
muscle cell apoptotic process	GO:0010657	30	0.307
immune system process	GO:0002376	204	0.298
cell cycle	GO:0007049	101	0.296
regulation of myeloid cell apoptotic process	GO:0033032	6	0.295
regulation of nucleocytoplasmic transport	GO:0046822	28	0.294
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.289
protein localization to organelle	GO:0033365	57	0.279
purine ribonucleoside monophosphate catabolic process	GO:0009169	55	0.275	Yeast
purine nucleoside monophosphate catabolic process	GO:0009128	55	0.271	Yeast
negative regulation of macromolecule metabolic process	GO:0010605	260	0.269
positive regulation of lamellipodium assembly	GO:0010592	4	0.269
nucleoside triphosphate catabolic process	GO:0009143	123	0.265	Yeast
negative regulation of neuron apoptotic process	GO:0043524	45	0.265
cytoskeleton organization	GO:0007010	111	0.254
regulation of molecular function	GO:0065009	398	0.248	Yeast
regulation of phosphorylation	GO:0042325	248	0.245
nucleoside monophosphate catabolic process	GO:0009125	56	0.243	Yeast
protein targeting to nucleus	GO:0044744	35	0.240
positive regulation of developmental process	GO:0051094	283	0.238
atp catabolic process	GO:0006200	54	0.234	Yeast
regulation of multicellular organismal development	GO:2000026	376	0.233
urogenital system development	GO:0001655	78	0.232
regulation of cellular protein metabolic process	GO:0032268	267	0.232
intracellular receptor signaling pathway	GO:0030522	35	0.229
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.225
regulation of protein modification process	GO:0031399	194	0.223
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.223	Yeast
chromosome segregation	GO:0007059	2	0.218
cellular catabolic process	GO:0044248	295	0.217	Yeast
regulation of nucleic acid templated transcription	GO:1903506	380	0.213
intracellular transport	GO:0046907	185	0.209
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.209
multicellular organismal movement	GO:0050879	17	0.208
positive regulation of cellular component biogenesis	GO:0044089	55	0.207
positive regulation of homeostatic process	GO:0032846	49	0.207
cellular macromolecule localization	GO:0070727	122	0.206
regulation of protein targeting	GO:1903533	28	0.205
negative regulation of programmed cell death	GO:0043069	183	0.203
regulation of organelle organization	GO:0033043	80	0.199
defense response	GO:0006952	194	0.199
regulation of protein localization	GO:0032880	81	0.198
regulation of microtubule polymerization	GO:0031113	8	0.198
regulation of catalytic activity	GO:0050790	304	0.196	Yeast
regulation of microtubule cytoskeleton organization	GO:0070507	14	0.195
protein complex biogenesis	GO:0070271	263	0.192
regulation of chromosome organization	GO:0033044	9	0.181
rna metabolic process	GO:0016070	406	0.181
cellular protein complex assembly	GO:0043623	44	0.180
rna biosynthetic process	GO:0032774	380	0.179
positive regulation of muscle contraction	GO:0045933	22	0.178
atp metabolic process	GO:0046034	72	0.177	Yeast
spindle organization	GO:0007051	2	0.175
aromatic compound catabolic process	GO:0019439	168	0.175	Yeast
regulation of vasculature development	GO:1901342	44	0.174
cell motility	GO:0048870	202	0.172
positive regulation of protein transport	GO:0051222	41	0.167
nucleoside phosphate catabolic process	GO:1901292	140	0.166	Yeast
regulation of protein import into nucleus	GO:0042306	24	0.165
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.163	Yeast
protein phosphorylation	GO:0006468	345	0.160
regulation of neuron differentiation	GO:0045664	208	0.159
regulation of neuron apoptotic process	GO:0043523	83	0.155
regulation of phosphate metabolic process	GO:0019220	349	0.155
regulation of cell development	GO:0060284	263	0.154
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.153	Yeast
positive regulation of gene expression	GO:0010628	244	0.153
blood vessel development	GO:0001568	69	0.152
positive regulation of phosphate metabolic process	GO:0045937	262	0.151
heart process	GO:0003015	57	0.148
organophosphate catabolic process	GO:0046434	148	0.143	Yeast
purine nucleotide catabolic process	GO:0006195	136	0.143	Yeast
purine containing compound metabolic process	GO:0072521	253	0.143	Yeast
developmental process involved in reproduction	GO:0003006	159	0.142
nucleoside phosphate metabolic process	GO:0006753	283	0.140	Yeast
regulation of cellular localization	GO:0060341	263	0.138
protein import into nucleus translocation	GO:0000060	9	0.137
positive regulation of protein modification process	GO:0031401	142	0.137
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.136
cellular macromolecule catabolic process	GO:0044265	29	0.135
positive regulation of molecular function	GO:0044093	230	0.134
positive regulation of biosynthetic process	GO:0009891	319	0.134
negative regulation of cellular component organization	GO:0051129	83	0.133
regulation of rna biosynthetic process	GO:2001141	381	0.129
muscle system process	GO:0003012	115	0.129
nucleotide catabolic process	GO:0009166	139	0.129	Yeast
microtubule polymerization	GO:0046785	9	0.126
negative regulation of metabolic process	GO:0009892	331	0.119	Yeast
regulation of protein kinase activity	GO:0045859	105	0.117
proteolysis	GO:0006508	175	0.114
regulation of anatomical structure morphogenesis	GO:0022603	141	0.112
anatomical structure morphogenesis	GO:0009653	298	0.112
regulation of cellular component biogenesis	GO:0044087	86	0.111
positive regulation of cell development	GO:0010720	176	0.110
regulation of nervous system development	GO:0051960	264	0.110
circulatory system process	GO:0003013	183	0.110
single organism reproductive process	GO:0044702	297	0.109
cellular macromolecular complex assembly	GO:0034622	58	0.109
neuron apoptotic process	GO:0051402	88	0.107
sensory perception	GO:0007600	101	0.107
regulation of protein transport	GO:0051223	68	0.105
response to unfolded protein	GO:0006986	6	0.104
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.104	Yeast
response to cytokine	GO:0034097	215	0.104
cation transport	GO:0006812	382	0.103
metal ion transport	GO:0030001	289	0.101
regulation of system process	GO:0044057	208	0.100
neuron projection morphogenesis	GO:0048812	122	0.100
cellular protein localization	GO:0034613	122	0.100
response to estrogen	GO:0043627	232	0.099
nuclear import	GO:0051170	35	0.097
response to radiation	GO:0009314	137	0.097
transcription dna templated	GO:0006351	377	0.097
chromosome organization	GO:0051276	36	0.097
cellular nitrogen compound catabolic process	GO:0044270	163	0.096	Yeast
regulation of cell projection organization	GO:0031344	175	0.096
positive regulation of transport	GO:0051050	245	0.095
neuron death	GO:0070997	127	0.092
vasculature development	GO:0001944	70	0.092
positive regulation of organelle organization	GO:0010638	48	0.091
positive regulation of response to stimulus	GO:0048584	285	0.090
positive regulation of protein metabolic process	GO:0051247	178	0.087
reproductive structure development	GO:0048608	128	0.086
regulation of microtubule polymerization or depolymerization	GO:0031110	12	0.085
regulation of cell proliferation	GO:0042127	359	0.085
dna replication	GO:0006260	37	0.083
response to osmotic stress	GO:0006970	42	0.083
carbohydrate derivative metabolic process	GO:1901135	346	0.083	Yeast
immune response	GO:0006955	104	0.082
single fertilization	GO:0007338	3	0.082
detection of visible light	GO:0009584	3	0.081
positive regulation of cellular protein metabolic process	GO:0032270	167	0.079
neuron migration	GO:0001764	21	0.079
protein polymerization	GO:0051258	22	0.079
nucleocytoplasmic transport	GO:0006913	48	0.078
negative regulation of cellular protein metabolic process	GO:0032269	106	0.077
catabolic process	GO:0009056	351	0.077	Yeast
negative regulation of rna metabolic process	GO:0051253	123	0.076
regulation of neurogenesis	GO:0050767	247	0.075
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.075
cellular component morphogenesis	GO:0032989	155	0.074
positive regulation of cellular catabolic process	GO:0031331	71	0.074
locomotion	GO:0040011	237	0.073
blood circulation	GO:0008015	183	0.073
regulation of muscle contraction	GO:0006937	53	0.072
single organism catabolic process	GO:0044712	283	0.072	Yeast
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.072
microtubule based process	GO:0007017	36	0.071
transmembrane transport	GO:0055085	412	0.071
mitochondrion organization	GO:0007005	35	0.071
protein localization to mitochondrion	GO:0070585	7	0.070
glycosyl compound metabolic process	GO:1901657	182	0.070	Yeast
reproductive process	GO:0022414	372	0.069
skeletal muscle contraction	GO:0003009	17	0.068
regulation of cell differentiation	GO:0045595	320	0.067
regulation of muscle system process	GO:0090257	79	0.067
regulation of phosphorus metabolic process	GO:0051174	349	0.066
regulation of defense response	GO:0031347	68	0.065
regulation of establishment of protein localization	GO:0070201	69	0.063
single organism cellular localization	GO:1902580	102	0.063
dna metabolic process	GO:0006259	96	0.063
positive regulation of protein serine threonine kinase activity	GO:0071902	52	0.063
cell projection morphogenesis	GO:0048858	123	0.063
single organism biosynthetic process	GO:0044711	342	0.062
protein catabolic process	GO:0030163	30	0.062
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.062
regulation of response to stress	GO:0080134	126	0.062
reproductive system development	GO:0061458	128	0.061
regulation of hydrolase activity	GO:0051336	143	0.061
cardiovascular system development	GO:0072358	134	0.061
regulation of angiogenesis	GO:0045765	39	0.061
localization of cell	GO:0051674	202	0.060
regulation of neuron death	GO:1901214	115	0.060
growth	GO:0040007	165	0.059
regulation of microtubule based process	GO:0032886	14	0.059
transcription from rna polymerase ii promoter	GO:0006366	252	0.059
negative regulation of cell differentiation	GO:0045596	99	0.059
regulation of protein phosphorylation	GO:0001932	183	0.059
neuron development	GO:0048666	286	0.059
chemotaxis	GO:0006935	66	0.058
regulation of nucleotide catabolic process	GO:0030811	65	0.058
ribonucleoprotein complex biogenesis	GO:0022613	10	0.057
cellular response to stress	GO:0033554	269	0.057
positive regulation of cytoplasmic transport	GO:1903651	32	0.056
regulation of transcription dna templated	GO:0006355	374	0.056
negative regulation of protein metabolic process	GO:0051248	114	0.056
ribonucleotide metabolic process	GO:0009259	231	0.055	Yeast
mitochondrial transport	GO:0006839	19	0.055
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.055
positive regulation of cellular biosynthetic process	GO:0031328	295	0.054
embryo implantation	GO:0007566	15	0.054
cellular component movement	GO:0006928	248	0.054
cellular response to organic cyclic compound	GO:0071407	202	0.053
reproduction	GO:0000003	245	0.053
positive regulation of transferase activity	GO:0051347	81	0.052
double strand break repair	GO:0006302	1	0.052
peptidyl amino acid modification	GO:0018193	126	0.051
negative regulation of cell proliferation	GO:0008285	119	0.051
positive regulation of catalytic activity	GO:0043085	184	0.051
positive regulation of lymphocyte mediated immunity	GO:0002708	7	0.051
cell morphogenesis involved in differentiation	GO:0000904	119	0.050
organophosphate metabolic process	GO:0019637	370	0.050	Yeast
nucleic acid templated transcription	GO:0097659	379	0.050
response to extracellular stimulus	GO:0009991	380	0.050
regulation of metal ion transport	GO:0010959	118	0.049
isotype switching to igg isotypes	GO:0048291	1	0.049
organonitrogen compound catabolic process	GO:1901565	179	0.049	Yeast
immune effector process	GO:0002252	53	0.048
regulation of adaptive immune response	GO:0002819	8	0.048
mitotic spindle organization	GO:0007052	2	0.048
glycosyl compound catabolic process	GO:1901658	126	0.047	Yeast
rhythmic process	GO:0048511	156	0.047
negative regulation of transcription dna templated	GO:0045892	116	0.047
response to alkaloid	GO:0043279	132	0.047
positive regulation of programmed cell death	GO:0043068	157	0.047
regulation of protein localization to nucleus	GO:1900180	25	0.046
heterocycle catabolic process	GO:0046700	167	0.046	Yeast
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.046	Yeast
regulation of blood circulation	GO:1903522	110	0.046
ribonucleotide catabolic process	GO:0009261	136	0.046	Yeast
purine nucleoside metabolic process	GO:0042278	169	0.046	Yeast
cell projection organization	GO:0030030	302	0.046
cellular response to oxidative stress	GO:0034599	76	0.046
response to topologically incorrect protein	GO:0035966	8	0.046
ribonucleoside metabolic process	GO:0009119	174	0.045	Yeast
ribonucleoprotein complex subunit organization	GO:0071826	8	0.045
cellular response to heat	GO:0034605	9	0.044
vascular process in circulatory system	GO:0003018	96	0.044
regulation of striated muscle contraction	GO:0006942	21	0.044
myeloid cell apoptotic process	GO:0033028	6	0.044
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.044
mitotic cell cycle	GO:0000278	49	0.044
cell cell signaling	GO:0007267	335	0.043
positive regulation of blood circulation	GO:1903524	65	0.043
sexual reproduction	GO:0019953	148	0.043
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.043
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.043	Yeast
positive regulation of phosphorus metabolic process	GO:0010562	262	0.043
negative regulation of gene expression	GO:0010629	199	0.043
nucleoside triphosphate metabolic process	GO:0009141	144	0.042	Yeast
regulation of retinal cell programmed cell death	GO:0046668	1	0.042
positive regulation of protein import into nucleus	GO:0042307	14	0.042
positive regulation of apoptotic process	GO:0043065	154	0.042
regulation of kinase activity	GO:0043549	117	0.042
cell migration	GO:0016477	197	0.042
response to light stimulus	GO:0009416	52	0.041
nucleotide metabolic process	GO:0009117	279	0.041	Yeast
angiogenesis	GO:0001525	53	0.041
homeostatic process	GO:0042592	331	0.041
response to nutrient	GO:0007584	248	0.041
cytoplasmic transport	GO:0016482	115	0.041
response to wounding	GO:0009611	254	0.041
response to ammonium ion	GO:0060359	71	0.041
carbohydrate derivative catabolic process	GO:1901136	147	0.041	Yeast
regulation of signal transduction	GO:0009966	318	0.040
response to purine containing compound	GO:0014074	126	0.040
circulatory system development	GO:0072359	134	0.040
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.040	Yeast
macromolecule catabolic process	GO:0009057	58	0.039
detection of abiotic stimulus	GO:0009582	13	0.039
regulation of intracellular transport	GO:0032386	65	0.039
regulation of response to external stimulus	GO:0032101	106	0.039
organic cyclic compound catabolic process	GO:1901361	175	0.038	Yeast
positive regulation of immune system process	GO:0002684	90	0.038
leukocyte mediated cytotoxicity	GO:0001909	10	0.038
regulation of transferase activity	GO:0051338	123	0.037
regulation of anatomical structure size	GO:0090066	135	0.037
intracellular signal transduction	GO:0035556	314	0.037
response to decreased oxygen levels	GO:0036293	237	0.037
er associated ubiquitin dependent protein catabolic process	GO:0030433	1	0.037
protein localization to nucleus	GO:0034504	39	0.037
eye morphogenesis	GO:0048592	4	0.036
purine ribonucleoside metabolic process	GO:0046128	168	0.036	Yeast
detection of external stimulus	GO:0009581	13	0.035
chlorinated hydrocarbon metabolic process	GO:0042196	4	0.035
cell morphogenesis	GO:0000902	142	0.035
positive regulation of phosphorylation	GO:0042327	177	0.035
regulation of peptidase activity	GO:0052547	55	0.035
regulation of homeostatic process	GO:0032844	101	0.034
response to hypoxia	GO:0001666	231	0.034
positive regulation of cell death	GO:0010942	184	0.034
sensory perception of light stimulus	GO:0050953	3	0.034
ribonucleoside catabolic process	GO:0042454	126	0.033	Yeast
negative regulation of cellular biosynthetic process	GO:0031327	161	0.033
response to cadmium ion	GO:0046686	35	0.033
blood vessel morphogenesis	GO:0048514	58	0.033
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.032
musculoskeletal movement	GO:0050881	17	0.032
response to reactive oxygen species	GO:0000302	120	0.032
regulation of heart contraction	GO:0008016	48	0.032
regulation of intracellular protein transport	GO:0033157	34	0.032
response to metal ion	GO:0010038	253	0.031
protein oligomerization	GO:0051259	191	0.031
regulation of ion transport	GO:0043269	245	0.031
regulation of dna metabolic process	GO:0051052	60	0.031
regulation of tube size	GO:0035150	89	0.031
cellular amine metabolic process	GO:0044106	38	0.031
divalent inorganic cation transport	GO:0072511	134	0.031
cell redox homeostasis	GO:0045454	1	0.031
axon development	GO:0061564	96	0.031
regulation of intracellular signal transduction	GO:1902531	218	0.030
organic acid biosynthetic process	GO:0016053	83	0.030
negative regulation of molecular function	GO:0044092	133	0.030	Yeast
t cell mediated immunity	GO:0002456	7	0.029
nucleobase containing small molecule metabolic process	GO:0055086	316	0.029	Yeast
toxin transport	GO:1901998	3	0.029
cell activation	GO:0001775	97	0.029
divalent metal ion transport	GO:0070838	132	0.029
response to atp	GO:0033198	13	0.029
negative regulation of biosynthetic process	GO:0009890	168	0.029
purine ribonucleotide metabolic process	GO:0009150	227	0.028	Yeast
ribose phosphate metabolic process	GO:0019693	235	0.028	Yeast
response to oxygen levels	GO:0070482	265	0.028
visual perception	GO:0007601	3	0.028
cardiac chamber development	GO:0003205	1	0.028
negative regulation of phosphorus metabolic process	GO:0010563	80	0.028
organelle fission	GO:0048285	25	0.027
sex differentiation	GO:0007548	113	0.027
establishment of protein localization to membrane	GO:0090150	16	0.027
positive regulation of protein phosphorylation	GO:0001934	135	0.027
proteolysis involved in cellular protein catabolic process	GO:0051603	19	0.027
cellular response to dna damage stimulus	GO:0006974	19	0.027
multi organism reproductive process	GO:0044703	262	0.027
protein transmembrane transport	GO:0071806	2	0.027
actin filament based process	GO:0030029	86	0.027
response to nutrient levels	GO:0031667	370	0.026
purine ribonucleotide catabolic process	GO:0009154	136	0.026	Yeast
purine nucleotide metabolic process	GO:0006163	229	0.026	Yeast
neuron recognition	GO:0008038	9	0.025
male sex differentiation	GO:0046661	64	0.025
nucleoside metabolic process	GO:0009116	179	0.025	Yeast
response to peptide hormone	GO:0043434	278	0.025
regulation of rna metabolic process	GO:0051252	391	0.025
positive regulation of signal transduction	GO:0009967	175	0.025
positive regulation of lamellipodium organization	GO:1902745	4	0.025
positive regulation of transcription dna templated	GO:0045893	197	0.025
regulation of cysteine type endopeptidase activity	GO:2000116	32	0.025
protein ubiquitination	GO:0016567	28	0.025
regulation of cell morphogenesis	GO:0022604	77	0.024
heart contraction	GO:0060047	57	0.024
cellular response to oxygen containing compound	GO:1901701	386	0.024
embryonic appendage morphogenesis	GO:0035113	4	0.024
organelle localization	GO:0051640	55	0.024
negative regulation of rna biosynthetic process	GO:1902679	118	0.024
protein localization to membrane	GO:0072657	36	0.024
negative regulation of cell development	GO:0010721	82	0.024
inflammatory response	GO:0006954	150	0.024
gland development	GO:0048732	155	0.024
protein processing	GO:0016485	68	0.023
regulation of response to wounding	GO:1903034	69	0.023
regulation of immune system process	GO:0002682	123	0.023
multicellular organism growth	GO:0035264	1	0.023
positive regulation of dna metabolic process	GO:0051054	39	0.023
dna damage response detection of dna damage	GO:0042769	2	0.023
muscle contraction	GO:0006936	88	0.023
positive regulation of neuron differentiation	GO:0045666	126	0.023
cell part morphogenesis	GO:0032990	123	0.023
axonogenesis	GO:0007409	71	0.023
purine nucleoside catabolic process	GO:0006152	124	0.023	Yeast
regulation of leukocyte mediated immunity	GO:0002703	19	0.022
positive regulation of cell size	GO:0045793	8	0.022
positive regulation of cell projection organization	GO:0031346	111	0.022
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.022
protein homooligomerization	GO:0051260	91	0.022
regulation of cell migration	GO:0030334	128	0.022
positive regulation of heart contraction	GO:0045823	15	0.021
regulation of immune response	GO:0050776	55	0.021
ovulation cycle	GO:0042698	67	0.021
regulation of jnk cascade	GO:0046328	19	0.021
response to starvation	GO:0042594	59	0.021
necroptotic process	GO:0070266	2	0.021
regulation of cell size	GO:0008361	37	0.021
positive regulation of transcription initiation from rna polymerase ii promoter	GO:0060261	3	0.020
negative regulation of multicellular organismal process	GO:0051241	203	0.020
positive regulation of protein kinase activity	GO:0045860	73	0.020
histone modification	GO:0016570	30	0.020
dna templated transcription initiation	GO:0006352	4	0.020
purine containing compound catabolic process	GO:0072523	138	0.020	Yeast
response to inorganic substance	GO:0010035	377	0.020
neurological system process	GO:0050877	219	0.020
ribonucleoside monophosphate catabolic process	GO:0009158	55	0.020	Yeast
muscle structure development	GO:0061061	87	0.019
positive regulation of intracellular transport	GO:0032388	39	0.019
nucleobase containing compound catabolic process	GO:0034655	152	0.019	Yeast
taxis	GO:0042330	67	0.019
developmental growth	GO:0048589	100	0.019
multicellular organism reproduction	GO:0032504	233	0.019
cardiac muscle contraction	GO:0060048	27	0.019
regulation of protein processing	GO:0070613	50	0.018
placenta development	GO:0001890	22	0.018
positive regulation of hydrolase activity	GO:0051345	86	0.018
cellular response to topologically incorrect protein	GO:0035967	3	0.018
regulation of protein serine threonine kinase activity	GO:0071900	64	0.017
somatic recombination of immunoglobulin genes involved in immune response	GO:0002204	1	0.017
prostate gland development	GO:0030850	9	0.017
organelle assembly	GO:0070925	22	0.017
response to ethanol	GO:0045471	162	0.017
regulation of ubiquitin protein transferase activity	GO:0051438	1	0.017
cellular response to lipid	GO:0071396	201	0.017
covalent chromatin modification	GO:0016569	30	0.017
regulation of protein complex assembly	GO:0043254	33	0.017
chromatin assembly or disassembly	GO:0006333	1	0.017
regulation of t cell mediated immunity	GO:0002709	6	0.017
cellular amino acid metabolic process	GO:0006520	107	0.017
g protein coupled receptor signaling pathway	GO:0007186	242	0.017
positive regulation of kinase activity	GO:0033674	77	0.017
microtubule anchoring	GO:0034453	1	0.017
positive regulation of catabolic process	GO:0009896	78	0.017
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.017
neurotransmitter secretion	GO:0007269	33	0.017
negative regulation of protein modification process	GO:0031400	52	0.017
calcium ion transport	GO:0006816	131	0.017
positive regulation of signaling	GO:0023056	270	0.016
chromatin modification	GO:0016568	33	0.016
cellular response to inorganic substance	GO:0071241	65	0.016
neuron differentiation	GO:0030182	368	0.016
transmission of nerve impulse	GO:0019226	42	0.016
negative regulation of developmental process	GO:0051093	125	0.016
gliogenesis	GO:0042063	93	0.016
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.016	Yeast
cell fate determination	GO:0001709	2	0.015
carboxylic acid metabolic process	GO:0019752	289	0.015
negative regulation of microtubule polymerization or depolymerization	GO:0031111	6	0.015
negative regulation of protein phosphorylation	GO:0001933	44	0.015
regulation of protein maturation	GO:1903317	50	0.015
antigen receptor mediated signaling pathway	GO:0050851	1	0.015
positive regulation of rna biosynthetic process	GO:1902680	197	0.015
carbohydrate derivative biosynthetic process	GO:1901137	124	0.015
cellular protein catabolic process	GO:0044257	19	0.014
negative regulation of neuron death	GO:1901215	69	0.014
gonad development	GO:0008406	104	0.014
negative regulation of catalytic activity	GO:0043086	103	0.014	Yeast
regulation of cellular amino acid metabolic process	GO:0006521	2	0.014
mrna splicing via spliceosome	GO:0000398	7	0.014
kidney development	GO:0001822	67	0.014
myeloid leukocyte activation	GO:0002274	36	0.014
negative regulation of endopeptidase activity	GO:0010951	36	0.014
cellular response to reactive oxygen species	GO:0034614	55	0.014
fertilization	GO:0009566	3	0.014
regulation of cellular component size	GO:0032535	51	0.014
secretion by cell	GO:0032940	248	0.014

Stip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.040
disease of anatomical entity	DOID:7	0.040
central nervous system disease	DOID:331	0.025

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